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SVVLVVAPEALSAAAANIAGIGSSLGAANAAAATPTTTVLAAGTDEISTTIATLFCGYARDYQNLSTQLA SFHQQFLQALTGSANSYTAAEAANTNPLQALEQQLLAAINAPTQTLLGRPLIGNGANGAPGQNGADGGLL WGTGGTGDATHPAGGNGGNAGLIGNGGAGGTGYSPATGTGAGGGAGGSGGRGGFFFGSGGAGGDGGASAG GTSPGGQSAGAGGNGGSGGATGLCGTGGAGGGKGGSSGATASLGGIGGSGGAGGDGGWMYGDGGAGGAGG KGGTGGQGLGIGGIGGDGGGGGDGGAGGNGGWVVGNGGGGDGGLSVGPHSGRGAGGGGGGGGSALLIGNG GNGGAGGTGLPEGTGGTGGTGGLLFGTPGMHG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1837 | - | - | 100% (383) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_1838 | - | e-148 | 70.92% (392) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_3292 | - | e-116 | 56.68% (404) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1476c | PE_PGRS26 | 1e-132 | 61.02% (413) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 2e-61 | 52.67% (262) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1441c | PE_PGRS26 | 1e-131 | 60.77% (413) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 2e-13 | 38.46% (91) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 1e-28 | 32.54% (338) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_2248 | - | 0.0 | 83.56% (438) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 2e-23 | 44.38% (169) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 5e-53 | 41.36% (353) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 7e-39 | 39.71% (277) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_3867 | - | 3e-62 | 40.79% (407) | PE-PGRS family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_1837|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2248|M.marinum_M --------------------------------------------------
Mb1476c|M.bovis_AF2122/97 --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mvan_3867|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_1837|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2248|M.marinum_M --------------------------------------------------
Mb1476c|M.bovis_AF2122/97 --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mvan_3867|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_1837|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2248|M.marinum_M --------------------------------------------------
Mb1476c|M.bovis_AF2122/97 --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mvan_3867|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_1837|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2248|M.marinum_M --------------------------------------------------
Mb1476c|M.bovis_AF2122/97 --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mvan_3867|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------VEAASYVADP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_1837|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2248|M.marinum_M --------------------------------------------------
Mb1476c|M.bovis_AF2122/97 --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mvan_3867|M.vanbaalenii_PYR-1 --------------------------------------------MPHPIL
MAB_4284c|M.abscessus_ATCC_199 EAALAN--------AGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATA
MUL_1837|M.ulcerans_Agy99 -----------------MSVVLVVAPEALSAAAANIAG------------
MMAR_2248|M.marinum_M -----------------MSAVLVVAPEALSAAAANIAG------------
Mb1476c|M.bovis_AF2122/97 -----------------MSNVMVVP-GMLSAAAADVAS------------
Rv1441c|M.tuberculosis_H37Rv -----------------MSNVMVVP-GMLSAAAADVAS------------
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNG---GLFGGNGGNGGNG
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNA---GLFG-NGGNGGVG
TH_3810|M.thermoresistible__bu -----------------------VDGDGGSGGRT---GLFS---------
Mvan_3867|M.vanbaalenii_PYR-1 ATAMAVGIAATAGAGALGDAPPTVNVTANKHVSA---TRLT---------
MAB_4284c|M.abscessus_ATCC_199 NPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDN---DFLSHNDTDFASH
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 SAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALR---------
MUL_1837|M.ulcerans_Agy99 --------------------IGSSLGAANAAAATPTTTVLAAGTDEISTT
MMAR_2248|M.marinum_M --------------------IGSSLGAANAAAVTPTTTVLAAGTDEVSGA
Mb1476c|M.bovis_AF2122/97 --------------------IGAALSAANGAAAPTTAGVLAAGADEVSAA
Rv1441c|M.tuberculosis_H37Rv --------------------IGAALSAANGAAAPTTAGVLAAGADEVSAA
Mflv_5091|M.gilvum_PYR-GCK LGGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATG
MSMEG_0868|M.smegmatis_MC2_155 WAGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGG
TH_3810|M.thermoresistible__bu ----------------KLSRGGDGGDGGLG-------------GNGGHGG
Mvan_3867|M.vanbaalenii_PYR-1 -AVVTPNALYSAAPASDVVVLGAHGSLAVGEPRGVPQAGALAGASRAVPG
MAB_4284c|M.abscessus_ATCC_199 NPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDGAVAVG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -DALAARRIDNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLA
MUL_1837|M.ulcerans_Agy99 IATLFCGYARDYQNLSTQLASFHQQFLQALTGSANSYT------------
MMAR_2248|M.marinum_M IATLFCGYARDYQNLSTQLADFHQQFLQALTGSANSYT------------
Mb1476c|M.bovis_AF2122/97 IASLFSGYARDYQALSAQMARFHQQFVQALTASVGSYA------------
Rv1441c|M.tuberculosis_H37Rv IASLFSGYARDYQALSAQMARFHQQFVQALTASVGSYA------------
Mflv_5091|M.gilvum_PYR-GCK ATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG------------
MSMEG_0868|M.smegmatis_MC2_155 GTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGP
TH_3810|M.thermoresistible__bu GTGIIS--------------------LLSLAGNGGNGG------------
Mvan_3867|M.vanbaalenii_PYR-1 GLELSTGLATSRVHPLPERVNTDIEMVSAPTTSGPALR------------
MAB_4284c|M.abscessus_ATCC_199 GSNSGPIASGQGSTAVNGDVRDSNIINADHGSNVGVDQ------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VVETSDGSIPDVYKQQIRAESYGDAAGQLSAMVAGLEKLES---------
MUL_1837|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2248|M.marinum_M --------------------------------------------------
Mb1476c|M.bovis_AF2122/97 --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --AVG--SAGAAGEAGETGTWGNAGLPGKAGDAGGAG----AVGAAG---
MSMEG_0868|M.smegmatis_MC2_155 NVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTV
TH_3810|M.thermoresistible__bu ---------------------------------------------NG---
Mvan_3867|M.vanbaalenii_PYR-1 --------------------------------------------LGRATT
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------SQTRVGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------------------------------------LPGGLLL
MUL_1837|M.ulcerans_Agy99 -AAEAANTNPLQALEQQLLAAINAPT------------------------
MMAR_2248|M.marinum_M -AAEAANTNPLQALEQQLLAAINAPT------------------------
Mb1476c|M.bovis_AF2122/97 -AAEAANASPLQALEQQVLAAINAPT------------------------
Rv1441c|M.tuberculosis_H37Rv -AAEAANASPLQALEQQVLAAINAPT------------------------
Mflv_5091|M.gilvum_PYR-GCK AAGTVGTAGATGGTG----TGANGGAGGVG-----GVGGTGAAGAAGGAG
MSMEG_0868|M.smegmatis_MC2_155 DGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDG
TH_3810|M.thermoresistible__bu -YRTTDNNALDGGHG------GNGGN------------------------
Mvan_3867|M.vanbaalenii_PYR-1 PSVGSTGPAGAAAPGLFSLLIGNGDE------------------------
MAB_4284c|M.abscessus_ATCC_199 DYTNVSGHGSADIDKSVTVVDDHSQRNTTN--------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VGSGVDVAPLKQVLQTTTFLDVSVAE------------------------
MUL_1837|M.ulcerans_Agy99 -----QTLLGRPLIG---------------NGANGAPGQNGADGGLLWG-
MMAR_2248|M.marinum_M -----QTLLGRPLIG---------------NGANGAPGQNGADGGLLWGN
Mb1476c|M.bovis_AF2122/97 -----QTLLGRPLIG---------------NGADGLPGQNGGAGGLLWGN
Rv1441c|M.tuberculosis_H37Rv -----QTLLGRPLIG---------------NGADGLPGQNGGAGGLLWGN
Mflv_5091|M.gilvum_PYR-GCK ------GLGETGTTG--------------GAGGVGGQGTAGGTGGVGGIG
MSMEG_0868|M.smegmatis_MC2_155 GHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMG
TH_3810|M.thermoresistible__bu -----VGFFSLFNLG--------------GAGGWGGSGVDG---------
Mvan_3867|M.vanbaalenii_PYR-1 -----PGENGGWLIG---------------NGADGGPGQDGGRGGLLFGN
MAB_4284c|M.abscessus_ATCC_199 ---INDSFNTDRSTN---------------IGSGNTTNTEIGSHNQANIG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------EPETALARG-------------AALAAANAPLFASSTAALAYAQ
MUL_1837|M.ulcerans_Agy99 ------------------------------TGGTG---------------
MMAR_2248|M.marinum_M ----------------------------GGTGGTG---------------
Mb1476c|M.bovis_AF2122/97 ----------------------------GGNGGAG---------------
Rv1441c|M.tuberculosis_H37Rv ----------------------------GGNGGAG---------------
Mflv_5091|M.gilvum_PYR-GCK -----------------------GAGSTGAVGG-----------VGGKGI
MSMEG_0868|M.smegmatis_MC2_155 EIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKAS
TH_3810|M.thermoresistible__bu ---------------------------VDVVGG-----------------
Mvan_3867|M.vanbaalenii_PYR-1 ----------------------------GGRGG-----------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------TSTSAGG-----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------------------------DPGTGAVDQYS------------
MUL_1837|M.ulcerans_Agy99 -------DATHPAGGNGG-------------------------------N
MMAR_2248|M.marinum_M -------DATHPAGGNGG-------------------------------N
Mb1476c|M.bovis_AF2122/97 -------DAAHPNGGNGG-------------------------------D
Rv1441c|M.tuberculosis_H37Rv -------DAAHPNGGNGG-------------------------------D
Mflv_5091|M.gilvum_PYR-GCK QGGQGLQGGKGGDGGAGGKGGDADSMGS------------------AGAT
MSMEG_0868|M.smegmatis_MC2_155 GTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASAN
TH_3810|M.thermoresistible__bu ----------NPDGGTPG------------------------------AH
Mvan_3867|M.vanbaalenii_PYR-1 --------DALTSGGPAGRG----------------------------GD
MAB_4284c|M.abscessus_ATCC_199 ---------SAAVGGNAGLAGNAG----------------------LAGN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -LPDYLYVPVDPEPGDDELAYS------------------------AVGE
MUL_1837|M.ulcerans_Agy99 AGLIGNGGAGGTGYSPAT--------------------------------
MMAR_2248|M.marinum_M AGLIGNGGAGGTGYSPAS--------------------------------
Mb1476c|M.bovis_AF2122/97 AGMFGNGGAGGAGYSPAA--------------------------------
Rv1441c|M.tuberculosis_H37Rv AGMFGNGGAGGAGYSPAA--------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGKGGNGGNGGRGGLFG---------------KGGNAGNG----------
MSMEG_0868|M.smegmatis_MC2_155 GAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDP
TH_3810|M.thermoresistible__bu GESHTPGVYTDRQ-------------------------------------
Mvan_3867|M.vanbaalenii_PYR-1 AGLFGNGGDGGTGFVSS---------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAGLAG---------------------------------
MLBr_01183|M.leprae_Br4923 MPLFLNAEPQALTAAANT--------------------------------
MAV_4827|M.avium_104 EDAESPTVVIEKLFLPED--------------------------------
MUL_1837|M.ulcerans_Agy99 ----------------------GTGAGGGAGGSGGRGG------------
MMAR_2248|M.marinum_M ----------------------PSGANGGAGGIGGRGG------------
Mb1476c|M.bovis_AF2122/97 ----------------------GTGAAGGAGGAGGAGG------------
Rv1441c|M.tuberculosis_H37Rv ----------------------GTGAAGGAGGAGGAGG------------
Mflv_5091|M.gilvum_PYR-GCK ------------ADGGTGGAGGAGGTGG-TGGAGGTGG------------
MSMEG_0868|M.smegmatis_MC2_155 NGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHS
TH_3810|M.thermoresistible__bu ------------------GEDGEDGTGTGIGGRGGNGG------------
Mvan_3867|M.vanbaalenii_PYR-1 -------------------AAGTNAASGGTGGAGGNGG------------
MAB_4284c|M.abscessus_ATCC_199 -------------------NAGLAGNAGLAGNAGLAGN------------
MLBr_01183|M.leprae_Br4923 ----------------------LEGLSAATVASNAAAA------------
MAV_4827|M.avium_104 -------------SEPRRRPVLLVGSGLAVVGISAVLALEIALAIG----
. .
MUL_1837|M.ulcerans_Agy99 ----FFFGSGGAGGDGG-------ASAGGTSPGG-------QSAGAGGNG
MMAR_2248|M.marinum_M ----SLFGSGGAGGDGG-------AGAGGTSPGG-------QSAGAGGNG
Mb1476c|M.bovis_AF2122/97 ----WLSGNGGAGGNGG-------TGASGADGGGGLPPVPASPGGNGGGG
Rv1441c|M.tuberculosis_H37Rv ----WLSGNGGAGGNGG-------TGASGADGGGGLPPVPASPGGNGGGG
Mflv_5091|M.gilvum_PYR-GCK -----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 TGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDG
TH_3810|M.thermoresistible__bu ----SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNG
Mvan_3867|M.vanbaalenii_PYR-1 ----LLMGDGGKGGTGGRAISAEGPANGGNGGRGGNAGVLGGDAGGGGDG
MAB_4284c|M.abscessus_ATCC_199 ---AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG
MLBr_01183|M.leprae_Br4923 ----QLTTEIAPPAADDVS----ILLAHFFSGHG------RQYQAHASQG
MAV_4827|M.avium_104 ---IRTTGTVALQPTPNQHLIVPTEQAPAPPPVQASAPQPKISVPEPVAA
.
MUL_1837|M.ulcerans_Agy99 GSGGATGLCGTGGAG-------G-----GKGGS--------------SGA
MMAR_2248|M.marinum_M GSGGATGLCGTGGAG-------GSGGVGGKGGS--------------SGA
Mb1476c|M.bovis_AF2122/97 GAGGAAGMFGTGGAG-------GTGGDGGAGGAGD---------SPNSGA
Rv1441c|M.tuberculosis_H37Rv DAGGAAGMFGTGGAG-------GTGGDGGAGGAGD---------SPNSGA
Mflv_5091|M.gilvum_PYR-GCK GKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGG
TH_3810|M.thermoresistible__bu GHGGRGGFLGIGGSG-------GWGGHGGNGGD-----------TDADGG
Mvan_3867|M.vanbaalenii_PYR-1 GRGYSEKGPASGGAG-------GAGAAASTVGNG---------GSGGKGG
MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAGLAGNAG-----LAGNAGLAGNAGLAG--------NAAVAGN
MLBr_01183|M.leprae_Br4923 ATNHQDLIQSLLTSS------------SAYAGT-------------ETAN
MAV_4827|M.avium_104 PKPLSPPVAAPLPAAP-----PPAAPPLPEAPPIPAAPPVVPVPVVVPPV
:.
MUL_1837|M.ulcerans_Agy99 TASLG---------------GIGG--------------------------
MMAR_2248|M.marinum_M TASLG---------------GIGG--------------------------
Mb1476c|M.bovis_AF2122/97 NGARG---------------GDGG--------------------------
Rv1441c|M.tuberculosis_H37Rv NGARG---------------GDGG--------------------------
Mflv_5091|M.gilvum_PYR-GCK TGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG-------
MSMEG_0868|M.smegmatis_MC2_155 NGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRAT
TH_3810|M.thermoresistible__bu NGGDG---------------GNGGSAG-----------------------
Mvan_3867|M.vanbaalenii_PYR-1 SAQG----------------AGSANGG-----------------------
MAB_4284c|M.abscessus_ATCC_199 AAVAG----------NAAVAGNAAVGG-----------------------
MLBr_01183|M.leprae_Br4923 HDSL----------------------------------------------
MAV_4827|M.avium_104 PVPVP--------------VRIPVPDP-----------------------
MUL_1837|M.ulcerans_Agy99 ----------SGGAGGDGGWMYGDGGAG----------------------
MMAR_2248|M.marinum_M ----------SGGAGGDGGWMYGDGGAG----------------------
Mb1476c|M.bovis_AF2122/97 ----------NGAAGGAGGRLFGNGGAG----------------------
Rv1441c|M.tuberculosis_H37Rv ----------NGAAGGAGGRLFGNGGAG----------------------
Mflv_5091|M.gilvum_PYR-GCK ----------TGGTGGQGG-LGGGGGTG----------------------
MSMEG_0868|M.smegmatis_MC2_155 VIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTAT
TH_3810|M.thermoresistible__bu ----------RGGTGGLRGVFGINGGNG----------------------
Mvan_3867|M.vanbaalenii_PYR-1 ----------AGGSGGAGGFVSGDGGAG----------------------
MAB_4284c|M.abscessus_ATCC_199 -------VLNTGVSGAIGGSSHVGGAIN----------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------VSPPQLLAPPRLSVPQPVQP---------------------
MUL_1837|M.ulcerans_Agy99 ----GAG---GKGGTGGQG----------------LGIGGIGGDGGGGGD
MMAR_2248|M.marinum_M ----GAG---GKGGTGGQG----------------LGIGGIGGDGGGGGD
Mb1476c|M.bovis_AF2122/97 ----GNGGTAGQGGDGGTA----------------LGAGGIGGDGGTGGA
Rv1441c|M.tuberculosis_H37Rv ----GNGGTAGQGGDGGTA----------------LGAGGIGGDGGTGGA
Mflv_5091|M.gilvum_PYR-GCK -GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGF
MSMEG_0868|M.smegmatis_MC2_155 DGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGN
TH_3810|M.thermoresistible__bu --RAGLGGRGXXXXGGGVG---------------AAVRSGNGVFSGGGGT
Mvan_3867|M.vanbaalenii_PYR-1 -GGGGTALSAAGTGSGGSG-----------------GDGGNARGAGGGGR
MAB_4284c|M.abscessus_ATCC_199 ESLGGSGSVGGSTAVGGGAH--------------TGVGGGVSTGVGVGSH
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --PVRVPQPPSPPQVGGTVP---------------QSPPQHQTPPGEGTP
MUL_1837|M.ulcerans_Agy99 GGAG---GNGGWVVGNG---------------------------------
MMAR_2248|M.marinum_M GGAG---GNGGWVVGNGGIAGAGGHGGT------------------AGSG
Mb1476c|M.bovis_AF2122/97 GGTGGTAGIGGSSAGAGGAGGDGGAGGN------------------GGGS
Rv1441c|M.tuberculosis_H37Rv GGTGGTAGIGGSSAGAGGAGGDGGAGGT------------------GGGS
Mflv_5091|M.gilvum_PYR-GCK GGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSA
MSMEG_0868|M.smegmatis_MC2_155 GGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYG
TH_3810|M.thermoresistible__bu PSAGFGVPTTIQFPAGSCTSRAVSREG-----------------------
Mvan_3867|M.vanbaalenii_PYR-1 GGVGALGQSKDARGFGG-VGGAGGRSG-----------------------
MAB_4284c|M.abscessus_ATCC_199 VGGGISESLGGSGSVGGSTAVGGGAHTG-------------------VGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PKPDGPGNYGGGHVPTPGAGGSGGSGGG--------------------HV
MUL_1837|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2248|M.marinum_M GQSSGNA-DGGDGGTGGAG-----------------GTSGRLLGSAGDGG
Mb1476c|M.bovis_AF2122/97 SMIGGKGGTGGNGGVGGTG-----------------GASALTIGNGSSAG
Rv1441c|M.tuberculosis_H37Rv SMIGGKGGTGGNGGVGGTG-----------------GASALTIGNGSSAG
Mflv_5091|M.gilvum_PYR-GCK GKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAG
MSMEG_0868|M.smegmatis_MC2_155 STLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGG
TH_3810|M.thermoresistible__bu -IMPSSRAASARAG---------------------------AACASSTSR
Mvan_3867|M.vanbaalenii_PYR-1 -VTGTGGAGGAGGS----------------------GVSDTLDAAGGSGG
MAB_4284c|M.abscessus_ATCC_199 GVSTGVGVGSHVGG----------------------GISESLGGSGSVGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PTPGAGGSGGSGGG------------------------HVPTPGTGGPGG
MUL_1837|M.ulcerans_Agy99 GGGDGGLS--------------------------------VGPHSGRGAG
MMAR_2248|M.marinum_M GGGDGGLS--------------------------------VGPHSGRGAG
Mb1476c|M.bovis_AF2122/97 AGGAGGAGGTGGTGG-------------YIESLDGKGQAGNGGNGGNGAA
Rv1441c|M.tuberculosis_H37Rv AGGAGGAGGTGGTGG-------------YIESLDGKGQAGNGGNGGNGAA
Mflv_5091|M.gilvum_PYR-GCK ATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAA
MSMEG_0868|M.smegmatis_MC2_155 DGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGAD
TH_3810|M.thermoresistible__bu SRRSFCCSRA----------------------------------------
Mvan_3867|M.vanbaalenii_PYR-1 DGGDGSRGGIGGTGG-------------AAHSKSGNAQGGFAGDGGTGSR
MAB_4284c|M.abscessus_ATCC_199 STAVGGGAHTGVGGG----------VNTGVGVGSHVGGGISESLGGSGSV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 TGGSGGGHVPTPGAG-------------TPGGSGGGHLPFPGAGSTPGGS
MUL_1837|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2248|M.marinum_M --------------------------------------------------
Mb1476c|M.bovis_AF2122/97 --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG----
MSMEG_0868|M.smegmatis_MC2_155 GWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSV
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mvan_3867|M.vanbaalenii_PYR-1 -----------------------GSGGDGGDGGIGTSTTGKG--------
MAB_4284c|M.abscessus_ATCC_199 G----------------------GSTAVGGGAHTSAINDALGGSGS----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 G-------------------------------------------------
MUL_1837|M.ulcerans_Agy99 ---------------GGGGGGGSALLIGNGGNGGAGGTGLP------EGT
MMAR_2248|M.marinum_M ---------------GGGGGGGSALLIGNGGNGGAGGTGLP------DGT
Mb1476c|M.bovis_AF2122/97 ---------------GGAGGGGTG-AGGNGGAGGNGGDGGPSQGGGNPGF
Rv1441c|M.tuberculosis_H37Rv ---------------GGAGGGGTG-AGGNGGAGGNGGDGGPSQGGGNPGF
Mflv_5091|M.gilvum_PYR-GCK -------------AGGEGGEGGDGGKGGAG--AEGGAGGGGGAGGSGAGG
MSMEG_0868|M.smegmatis_MC2_155 WKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mvan_3867|M.vanbaalenii_PYR-1 -------------RGGNGGNGGGGIRAAPVGKAAKARRAAAVAEATAPAP
MAB_4284c|M.abscessus_ATCC_199 -------------VGGSTAVGGGAHTSAINESMNSSINASHSSSMNESFG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------GGHLPTPGAGTPGGGLGGFGGGHAPAPGGGLGGGGG
MUL_1837|M.ulcerans_Agy99 GGTGGTGG-----------LLFGTPGMHG--------
MMAR_2248|M.marinum_M GGNGGTGG-----------LLFGTPGMHG--------
Mb1476c|M.bovis_AF2122/97 GGDGGTGGPGGVGVPDGIGGANGAQGKHG--------
Rv1441c|M.tuberculosis_H37Rv GGDGGTGGPGGVGVPDGIGGANGAQGKHG--------
Mflv_5091|M.gilvum_PYR-GCK AG--GAGGSGGSGGSGGSGGSGGAAGDSDD-------
MSMEG_0868|M.smegmatis_MC2_155 SGNGGNGGNGGNGGADGTPGTAGTTGANNP-------
TH_3810|M.thermoresistible__bu -------------------------------------
Mvan_3867|M.vanbaalenii_PYR-1 DGVVSLGPAYAQSRSATNALCCNEFSCAVTNSSEW--
MAB_4284c|M.abscessus_ATCC_199 SSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH
MLBr_01183|M.leprae_Br4923 -------------------------------------
MAV_4827|M.avium_104 HAPAPGGGLGGFGGGHSGGGLGGLGGGHK--------