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SAVLVVAPEALSAAAANIAGIGSSLGAANAAAVTPTTTVLAAGTDEVSGAIATLFCGYARDYQNLSTQLA DFHQQFLQALTGSANSYTAAEAANTNPLQALEQQLLAAINAPTQTLLGRPLIGNGANGAPGQNGADGGLL WGNGGTGGTGDATHPAGGNGGNAGLIGNGGAGGTGYSPASPSGANGGAGGIGGRGGSLFGSGGAGGDGGA GAGGTSPGGQSAGAGGNGGSGGATGLCGTGGAGGSGGVGGKGGSSGATASLGGIGGSGGAGGDGGWMYGD GGAGGAGGKGGTGGQGLGIGGIGGDGGGGGDGGAGGNGGWVVGNGGIAGAGGHGGTAGSGGQSSGNADGG DGGTGGAGGTSGRLLGSAGDGGGGGDGGLSVGPHSGRGAGGGGGGGGSALLIGNGGNGGAGGTGLPDGTG GNGGTGGLLFGTPGMHG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_2248 | - | - | 100% (438) | PE-PGRS family protein |
M. marinum M | MMAR_2596 | - | e-153 | 58.30% (506) | PE-PGRS family protein |
M. marinum M | MMAR_2053 | - | e-139 | 52.71% (516) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1476c | PE_PGRS26 | 1e-148 | 58.08% (489) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 9e-76 | 50.63% (318) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv1441c | PE_PGRS26 | 1e-147 | 60.26% (468) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 1e-12 | 37.37% (99) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 9e-37 | 33.33% (366) | hypothetical protein MAB_4284c |
M. avium 104 | MAV_4827 | - | 3e-24 | 45.61% (171) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 9e-56 | 38.07% (457) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 9e-43 | 40.65% (310) | PUTATIVE - |
M. ulcerans Agy99 | MUL_1837 | - | 0.0 | 78.31% (438) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 6e-76 | 49.86% (345) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_2248|M.marinum_M -------------------------------------------------- MUL_1837|M.ulcerans_Agy99 -------------------------------------------------- Mb1476c|M.bovis_AF2122/97 -------------------------------------------------- Rv1441c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2248|M.marinum_M -------------------------------------------------- MUL_1837|M.ulcerans_Agy99 -------------------------------------------------- Mb1476c|M.bovis_AF2122/97 -------------------------------------------------- Rv1441c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP-- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2248|M.marinum_M -------------------------------------------------- MUL_1837|M.ulcerans_Agy99 -------------------------------------------------- Mb1476c|M.bovis_AF2122/97 -------------------------------------------------- Rv1441c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2248|M.marinum_M -------------------------------------------------- MUL_1837|M.ulcerans_Agy99 -------------------------------------------------- Mb1476c|M.bovis_AF2122/97 -------------------------------------------------- Rv1441c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------VEAASYVADP MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2248|M.marinum_M -------------------------------------------------- MUL_1837|M.ulcerans_Agy99 -------------------------------------------------- Mb1476c|M.bovis_AF2122/97 -------------------------------------------------- Rv1441c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 EAA-------------------------------------LANAGLSAVS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ------------------------------------------MNIVLGVS MMAR_2248|M.marinum_M ------MSAVLVVAPEALSAAAANIAGIGSSLGAANAAAVTPTT-TVLAA MUL_1837|M.ulcerans_Agy99 ------MSVVLVVAPEALSAAAANIAGIGSSLGAANAAAATPTT-TVLAA Mb1476c|M.bovis_AF2122/97 ------MSNVMVVP-GMLSAAAADVASIGAALSAANGAAAPTTA-GVLAA Rv1441c|M.tuberculosis_H37Rv ------MSNVMVVP-GMLSAAAADVASIGAALSAANGAAAPTTA-GVLAA Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNG-GNGLG Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNG-GNGLG MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNG-GVGWA TH_3810|M.thermoresistible__bu -------------------------------------------------V MAB_4284c|M.abscessus_ATCC_199 AAQVGAVMPVVAESVASNYGYQSQWVNTGN----PIHDLSGNLQ-NYYAA MLBr_01183|M.leprae_Br4923 -------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPP MAV_4827|M.avium_104 MAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGT MMAR_2248|M.marinum_M --GTDEVSGAIATLFCGYARDYQNLSTQLADFHQQFLQALTGSANSYTAA MUL_1837|M.ulcerans_Agy99 --GTDEISTTIATLFCGYARDYQNLSTQLASFHQQFLQALTGSANSYTAA Mb1476c|M.bovis_AF2122/97 --GADEVSAAIASLFSGYARDYQALSAQMARFHQQFVQALTASVGSYAAA Rv1441c|M.tuberculosis_H37Rv --GADEVSAAIASLFSGYARDYQALSAQMARFHQQFVQALTASVGSYAAA Mflv_5091|M.gilvum_PYR-GCK --GGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATG Mvan_1264|M.vanbaalenii_PYR-1 --SGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATG MSMEG_0868|M.smegmatis_MC2_155 --GLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGG TH_3810|M.thermoresistible__bu --DGDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGG MAB_4284c|M.abscessus_ATCC_199 --QPDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVD MLBr_01183|M.leprae_Br4923 --AADDVSILLAHFFSGHGRQYQAH------------------ASQGATN MAV_4827|M.avium_104 REGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAA . MMAR_2248|M.marinum_M EAANTNPLQALEQQLLAAINAPTQTLLGRPLIGNGANG------------ MUL_1837|M.ulcerans_Agy99 EAANTNPLQALEQQLLAAINAPTQTLLGRPLIGNGANG------------ Mb1476c|M.bovis_AF2122/97 EAANASPLQALEQQVLAAINAPTQTLLGRPLIGNGADG------------ Rv1441c|M.tuberculosis_H37Rv EAANASPLQALEQQVLAAINAPTQTLLGRPLIGNGADG------------ Mflv_5091|M.gilvum_PYR-GCK ATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG------------ Mvan_1264|M.vanbaalenii_PYR-1 ATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG------------ MSMEG_0868|M.smegmatis_MC2_155 GTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGP TH_3810|M.thermoresistible__bu GTGIIS--------------------LLSLAGNGGNGG------------ MAB_4284c|M.abscessus_ATCC_199 SFNRGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGP----------I MLBr_01183|M.leprae_Br4923 HQDLIQSL---------------------LTSSSAYAG------------ MAV_4827|M.avium_104 LAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIPD------------ . . MMAR_2248|M.marinum_M -----APGQNGADGGLLWGN------------------------------ MUL_1837|M.ulcerans_Agy99 -----APGQNGADGGLLWG------------------------------- Mb1476c|M.bovis_AF2122/97 -----LPGQNGGAGGLLWGN------------------------------ Rv1441c|M.tuberculosis_H37Rv -----LPGQNGGAGGLLWGN------------------------------ Mflv_5091|M.gilvum_PYR-GCK --AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG------------- Mvan_1264|M.vanbaalenii_PYR-1 --AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG------------- MSMEG_0868|M.smegmatis_MC2_155 NVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTV TH_3810|M.thermoresistible__bu ---NGYRTTDNNALDGGHGG------------------------------ MAB_4284c|M.abscessus_ATCC_199 ASGQGSTAVNGDVRDSNIIN------------------------------ MLBr_01183|M.leprae_Br4923 -----TETANHDSL------------------------------------ MAV_4827|M.avium_104 ----VYKQQIRAESYGDAAG------------------------------ MMAR_2248|M.marinum_M ----------------------------------------------GGTG MUL_1837|M.ulcerans_Agy99 ------------------------------------------------TG Mb1476c|M.bovis_AF2122/97 ----------------------------------------------GGNG Rv1441c|M.tuberculosis_H37Rv ----------------------------------------------GGNG Mflv_5091|M.gilvum_PYR-GCK ---AVGAAGAAG------TVGTAGATGGTG---------------TGANG Mvan_1264|M.vanbaalenii_PYR-1 ---AIGTAGVAG------AAGTAGATGGTG---------------VGGNG MSMEG_0868|M.smegmatis_MC2_155 DGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDG TH_3810|M.thermoresistible__bu ---------------------------------------------NGGNV MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------ADHGSNV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------QLSAMVA MMAR_2248|M.marinum_M GTGDATHPAG---------------------GNGGNAGLIG--------- MUL_1837|M.ulcerans_Agy99 GTGDATHPAG---------------------GNGGNAGLIG--------- Mb1476c|M.bovis_AF2122/97 GAGDAAHPNG---------------------GNGGDAGMFG--------- Rv1441c|M.tuberculosis_H37Rv GAGDAAHPNG---------------------GNGGDAGMFG--------- Mflv_5091|M.gilvum_PYR-GCK GAGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVG Mvan_1264|M.vanbaalenii_PYR-1 GAGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIG MSMEG_0868|M.smegmatis_MC2_155 GHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMG TH_3810|M.thermoresistible__bu GFFSLFNLGG--------------------AGGWGGSGVDG--------- MAB_4284c|M.abscessus_ATCC_199 GVDQSQTRVGGDYTN---------------VSGHGSADIDKSVTVVDDHS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GLEKLESLPGGLLLVG---------------SGVDVAPLKQVLQTTTFLD MMAR_2248|M.marinum_M -------------------------------------------------- MUL_1837|M.ulcerans_Agy99 -------------------------------------------------- Mb1476c|M.bovis_AF2122/97 -------------------------------------------------- Rv1441c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-------- Mvan_1264|M.vanbaalenii_PYR-1 GQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-------- MSMEG_0868|M.smegmatis_MC2_155 EIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKAS TH_3810|M.thermoresistible__bu ------------VDVVGGNP------------------------------ MAB_4284c|M.abscessus_ATCC_199 QRNTTNINDSFNTDRSTNIGSGNTTNTEIGSHN----------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 VSVAEEPETALARGAALAAANAPLFASSTAALAY---------------- MMAR_2248|M.marinum_M -------------------------------------------------N MUL_1837|M.ulcerans_Agy99 -------------------------------------------------N Mb1476c|M.bovis_AF2122/97 -------------------------------------------------N Rv1441c|M.tuberculosis_H37Rv -------------------------------------------------N Mflv_5091|M.gilvum_PYR-GCK -----LQGGKGGDGGAGGKGGDADSMGS------------------AGAT Mvan_1264|M.vanbaalenii_PYR-1 -----LQGGQGGDGGTGGTGGDATSMGE------------------AGAT MSMEG_0868|M.smegmatis_MC2_155 GTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASAN TH_3810|M.thermoresistible__bu ------------DGGTPG------------------------------AH MAB_4284c|M.abscessus_ATCC_199 ----------QANIGTS------------------------------TSA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -----------------------------------------------AQD MMAR_2248|M.marinum_M GGAGGTGYSPASPSGAN--------------------------------- MUL_1837|M.ulcerans_Agy99 GGAGGTGYSPATGTGAG--------------------------------- Mb1476c|M.bovis_AF2122/97 GGAGGAGYSPAAGTGAA--------------------------------- Rv1441c|M.tuberculosis_H37Rv GGAGGAGYSPAAGTGAA--------------------------------- Mflv_5091|M.gilvum_PYR-GCK GGKGGNGGNGGRGGLFG---------------KGGNAGNGAD-------- Mvan_1264|M.vanbaalenii_PYR-1 GGKGGNGGNGGRGSLFG---------------RGGNAGNGGN-------- MSMEG_0868|M.smegmatis_MC2_155 GAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDP TH_3810|M.thermoresistible__bu GESHTPGVYTDRQ------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GGSAAVGGNAGLAGNAG--------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 PGTGAVDQYSLPDYLYVP-------------------------------- MMAR_2248|M.marinum_M -----------------GGAGGIGGRGGSLFGSGGAGG------------ MUL_1837|M.ulcerans_Agy99 -----------------GGAGGSGGRGGFFFGSGGAGG------------ Mb1476c|M.bovis_AF2122/97 -----------------GGAGGAGGAGGWLSGNGGAGG------------ Rv1441c|M.tuberculosis_H37Rv -----------------GGAGGAGGAGGWLSGNGGAGG------------ Mflv_5091|M.gilvum_PYR-GCK --------------GGTGGAGGAGGTGG-TGGAGGTGG------------ Mvan_1264|M.vanbaalenii_PYR-1 --------------GGTGGNGGNGGTGG-TGGNGGTGG------------ MSMEG_0868|M.smegmatis_MC2_155 NGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHS TH_3810|M.thermoresistible__bu ------------------GEDGEDGTGTGIGGRGGNGG------------ MAB_4284c|M.abscessus_ATCC_199 ----------------LAGNAGLAGNAGLAGNAGLAGN------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------------VDPEPGDDELAYSAVGEEDAESPTVVIEKLFLP- MMAR_2248|M.marinum_M -----DGGAGAGGTSPGG-------QSAGAGGNGGSG----GATGLCGTG MUL_1837|M.ulcerans_Agy99 -----DGGASAGGTSPGG-------QSAGAGGNGGSG----GATGLCGTG Mb1476c|M.bovis_AF2122/97 -----NGGTGASGADGGGGLPPVPASPGGNGGGGGAG----GAAGMFGTG Rv1441c|M.tuberculosis_H37Rv -----NGGTGASGADGGGGLPPVPASPGGNGGGGDAG----GAAGMFGTG Mflv_5091|M.gilvum_PYR-GCK -----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTG Mvan_1264|M.vanbaalenii_PYR-1 -----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTG MSMEG_0868|M.smegmatis_MC2_155 TGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDG TH_3810|M.thermoresistible__bu ----SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNG MAB_4284c|M.abscessus_ATCC_199 ---AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLA----GNAGLAGNA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --EDSEPRRRPVLLVGSGLAVVGISAVLALEIALAIGIRTTGTVALQPTP MMAR_2248|M.marinum_M GAGGSGGVGGKGGS---------SGATASLGGIG------------GSGG MUL_1837|M.ulcerans_Agy99 GAGG-----GKGGS---------SGATASLGGIG------------GSGG Mb1476c|M.bovis_AF2122/97 GAGGTGGDGGAGGAGD----SPNSGANGARGGDG------------GNGA Rv1441c|M.tuberculosis_H37Rv GAGGTGGDGGAGGAGD----SPNSGANGARGGDG------------GNGA Mflv_5091|M.gilvum_PYR-GCK GKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGG Mvan_1264|M.vanbaalenii_PYR-1 GKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGG MSMEG_0868|M.smegmatis_MC2_155 GRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGG TH_3810|M.thermoresistible__bu GHGGRGGFLGIGGSG-------GWGGHGGNGGD-----------TDADGG MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAG----NAGLAGNAGLAGNAG--------LAGNAGL MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 NQHLIVPTEQAPAPPPVQASAPQPKISVPEPVAAPKPLSPPVAAPLPAAP MMAR_2248|M.marinum_M AGGDG-----------GWMYGDGGAGG----------------------- MUL_1837|M.ulcerans_Agy99 AGGDG-----------GWMYGDGGAGG----------------------- Mb1476c|M.bovis_AF2122/97 AGGAG-----------GRLFGNGGAGG----------------------- Rv1441c|M.tuberculosis_H37Rv AGGAG-----------GRLFGNGGAGG----------------------- Mflv_5091|M.gilvum_PYR-GCK TGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG------- Mvan_1264|M.vanbaalenii_PYR-1 TGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG------- MSMEG_0868|M.smegmatis_MC2_155 NGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRAT TH_3810|M.thermoresistible__bu NGGDG---------------GNGGSAG----------------------- MAB_4284c|M.abscessus_ATCC_199 AGNAG-------------LAGNAGLAG----------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 PPAAP-----------PLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPV MMAR_2248|M.marinum_M ----------AG---GKGGTGGQGLGIG---------------------- MUL_1837|M.ulcerans_Agy99 ----------AG---GKGGTGGQGLGIG---------------------- Mb1476c|M.bovis_AF2122/97 ----------NGGTAGQGGDGGTALGAG---------------------- Rv1441c|M.tuberculosis_H37Rv ----------NGGTAGQGGDGGTALGAG---------------------- Mflv_5091|M.gilvum_PYR-GCK ----------TGGTGGQGG-LGGGGGTG---------------------- Mvan_1264|M.vanbaalenii_PYR-1 ----------TGGTGGQGG-LGGVGGTG---------------------- MSMEG_0868|M.smegmatis_MC2_155 VIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTAT TH_3810|M.thermoresistible__bu ----------RGGTGGLRGVFGINGGNG---------------------- MAB_4284c|M.abscessus_ATCC_199 ----------NAAVAGNAAVAGNAAVAG---------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 PDPVSPPQLLAPPRLSVPQPVQPPVRVP---------------------- MMAR_2248|M.marinum_M ----GIGGDGGGGGDGGAG---GNGGW----------VVGNGGIAGAGGH MUL_1837|M.ulcerans_Agy99 ----GIGGDGGGGGDGGAG---GNGGW----------VVGNG-------- Mb1476c|M.bovis_AF2122/97 ----GIGGDGGTGGAGGTGGTAGIGGS----------SAGAGGAGGDGGA Rv1441c|M.tuberculosis_H37Rv ----GIGGDGGTGGAGGTGGTAGIGGS----------SAGAGGAGGDGGA Mflv_5091|M.gilvum_PYR-GCK -GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGF Mvan_1264|M.vanbaalenii_PYR-1 -GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGF MSMEG_0868|M.smegmatis_MC2_155 DGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGN TH_3810|M.thermoresistible__bu --RAGLGGRGXXXXGGGVGAAVRSG---------------NGVFSGGGGT MAB_4284c|M.abscessus_ATCC_199 --NAAVGGVLNTGVSGAIGGSSHVG---------GAINESLGGSGSVGGS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -QPPSPPQVGGTVPQSPPQHQTPPGEG-----TPPKPDGPGNYGGGHVPT MMAR_2248|M.marinum_M GGTAGSGGQSSGNA-DGGDGGTGGAGG---------------------TS MUL_1837|M.ulcerans_Agy99 -------------------------------------------------- Mb1476c|M.bovis_AF2122/97 GGNGGGSSMIGGKGGTGGNGGVGGTGG---------------------AS Rv1441c|M.tuberculosis_H37Rv GGTGGGSSMIGGKGGTGGNGGVGGTGG---------------------AS Mflv_5091|M.gilvum_PYR-GCK GGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSA Mvan_1264|M.vanbaalenii_PYR-1 GGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSA MSMEG_0868|M.smegmatis_MC2_155 GGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYG TH_3810|M.thermoresistible__bu PSAGFGVPTTIQFPAGSCTSRAVSREG----------------------- MAB_4284c|M.abscessus_ATCC_199 TAVGGGAHTGVGGGVSTGVGVGSHVGG--------------------GIS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 PGAGGSGGSGGGHVPTPGAGGSGGSGG---------------------GH MMAR_2248|M.marinum_M GRLLGSAGDGGGGGDGGLS------------------------------- MUL_1837|M.ulcerans_Agy99 -----------GGGDGGLS------------------------------- Mb1476c|M.bovis_AF2122/97 ALTIGNGSSAGAGGAGGAGGTGGTGGYI-------------ESLDGKGQA Rv1441c|M.tuberculosis_H37Rv ALTIGNGSSAGAGGAGGAGGTGGTGGYI-------------ESLDGKGQA Mflv_5091|M.gilvum_PYR-GCK GKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAG Mvan_1264|M.vanbaalenii_PYR-1 GTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQG MSMEG_0868|M.smegmatis_MC2_155 STLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGG TH_3810|M.thermoresistible__bu -IMPSSRAASARAG---------------------------AACASSTSR MAB_4284c|M.abscessus_ATCC_199 ESLGGSGSVGGSTAVGGGAHTGVGGGVS----------TGVGVGSHVGGG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 VPTPGTGGPGGTGGSGGGHVPTPGAGTP-----------------GGSGG MMAR_2248|M.marinum_M -VGPHSGRGAGGGGG-------------------GGGSALLIGNGGNGGA MUL_1837|M.ulcerans_Agy99 -VGPHSGRGAGGGGG-------------------GGGSALLIGNGGNGGA Mb1476c|M.bovis_AF2122/97 GNGGNGGNGAAGGAG-------------------GGGTG-AGGNGGAGGN Rv1441c|M.tuberculosis_H37Rv GNGGNGGNGAAGGAG-------------------GGGTG-AGGNGGAGGN Mflv_5091|M.gilvum_PYR-GCK ATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAA Mvan_1264|M.vanbaalenii_PYR-1 SAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAA MSMEG_0868|M.smegmatis_MC2_155 DGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGAD TH_3810|M.thermoresistible__bu SRRSFCCSRA---------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ISESLGGSGSVGGSTAVG---------GGAHTGVGGGVNTGVGVGSHVGG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GHLPFPGAGSTPGGS-------------------GGGHLPTPGAGTPGGG MMAR_2248|M.marinum_M GG------------------------------------------------ MUL_1837|M.ulcerans_Agy99 GG------------------------------------------------ Mb1476c|M.bovis_AF2122/97 GG------------------------------------------------ Rv1441c|M.tuberculosis_H37Rv GG------------------------------------------------ Mflv_5091|M.gilvum_PYR-GCK GKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG---- Mvan_1264|M.vanbaalenii_PYR-1 GKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG---- MSMEG_0868|M.smegmatis_MC2_155 GWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSV TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GISESLGGSGSVG-------GSTAVGGGAHTSAINDALGGSGSVGG---- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 LGGFG--------------------------------------------- MMAR_2248|M.marinum_M -------------------------------------TGLP------DGT MUL_1837|M.ulcerans_Agy99 -------------------------------------TGLP------EGT Mb1476c|M.bovis_AF2122/97 -------------------------------------DGGPSQGGGNPGF Rv1441c|M.tuberculosis_H37Rv -------------------------------------DGGPSQGGGNPGF Mflv_5091|M.gilvum_PYR-GCK -------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGG Mvan_1264|M.vanbaalenii_PYR-1 -------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGG MSMEG_0868|M.smegmatis_MC2_155 WKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------STAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSHGAAG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------------------------------GGHAPAPGGGLGGGGG MMAR_2248|M.marinum_M GGNGGTGG-----------LLFGTPGMHG- MUL_1837|M.ulcerans_Agy99 GGTGGTGG-----------LLFGTPGMHG- Mb1476c|M.bovis_AF2122/97 GGDGGTGGPGGVGVPDGIGGANGAQGKHG- Rv1441c|M.tuberculosis_H37Rv GGDGGTGGPGGVGVPDGIGGANGAQGKHG- Mflv_5091|M.gilvum_PYR-GCK AG--GAGGSGGSGGSGGSGGSGGAAGDSDD Mvan_1264|M.vanbaalenii_PYR-1 AG--GAGGSGGSGGSGGAGGSGGAAGDSD- MSMEG_0868|M.smegmatis_MC2_155 SGNGGNGGNGGNGGADGTPGTAGTTGANNP TH_3810|M.thermoresistible__bu ------------------------------ MAB_4284c|M.abscessus_ATCC_199 TGFEAQGHAQGHASETAHTTLPGAEHH--- MLBr_01183|M.leprae_Br4923 ------------------------------ MAV_4827|M.avium_104 HAPAPGGGLGGFGGGHSGGGLGGLGGGHK-