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M. marinum M MMAR_2248 (-)

annotation: PE-PGRS family protein
coordinates: 2704661 - 2705977
length: 438

SAVLVVAPEALSAAAANIAGIGSSLGAANAAAVTPTTTVLAAGTDEVSGAIATLFCGYARDYQNLSTQLA
DFHQQFLQALTGSANSYTAAEAANTNPLQALEQQLLAAINAPTQTLLGRPLIGNGANGAPGQNGADGGLL
WGNGGTGGTGDATHPAGGNGGNAGLIGNGGAGGTGYSPASPSGANGGAGGIGGRGGSLFGSGGAGGDGGA
GAGGTSPGGQSAGAGGNGGSGGATGLCGTGGAGGSGGVGGKGGSSGATASLGGIGGSGGAGGDGGWMYGD
GGAGGAGGKGGTGGQGLGIGGIGGDGGGGGDGGAGGNGGWVVGNGGIAGAGGHGGTAGSGGQSSGNADGG
DGGTGGAGGTSGRLLGSAGDGGGGGDGGLSVGPHSGRGAGGGGGGGGSALLIGNGGNGGAGGTGLPDGTG
GNGGTGGLLFGTPGMHG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2248--100% (438)PE-PGRS family protein
M. marinum MMMAR_2596-e-15358.30% (506) PE-PGRS family protein
M. marinum MMMAR_2053-e-13952.71% (516) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1476cPE_PGRS261e-14858.08% (489) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-9e-7650.63% (318) triple helix repeat-containing collagen
M. tuberculosis H37RvRv1441cPE_PGRS261e-14760.26% (468) PE-PGRS family protein
M. leprae Br4923MLBr_01183-1e-1237.37% (99) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-9e-3733.33% (366) hypothetical protein MAB_4284c
M. avium 104MAV_4827-3e-2445.61% (171) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-9e-5638.07% (457) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-9e-4340.65% (310) PUTATIVE -
M. ulcerans Agy99MUL_1837-0.078.31% (438) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-6e-7649.86% (345) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_2248|M.marinum_M               --------------------------------------------------
MUL_1837|M.ulcerans_Agy99           --------------------------------------------------
Mb1476c|M.bovis_AF2122/97           --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MMAR_2248|M.marinum_M               --------------------------------------------------
MUL_1837|M.ulcerans_Agy99           --------------------------------------------------
Mb1476c|M.bovis_AF2122/97           --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MMAR_2248|M.marinum_M               --------------------------------------------------
MUL_1837|M.ulcerans_Agy99           --------------------------------------------------
Mb1476c|M.bovis_AF2122/97           --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------MSIIDFILNLFRDP
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MMAR_2248|M.marinum_M               --------------------------------------------------
MUL_1837|M.ulcerans_Agy99           --------------------------------------------------
Mb1476c|M.bovis_AF2122/97           --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------------------------------VEAASYVADP
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MMAR_2248|M.marinum_M               --------------------------------------------------
MUL_1837|M.ulcerans_Agy99           --------------------------------------------------
Mb1476c|M.bovis_AF2122/97           --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1       S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      EAA-------------------------------------LANAGLSAVS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ------------------------------------------MNIVLGVS
                                                                                      

MMAR_2248|M.marinum_M               ------MSAVLVVAPEALSAAAANIAGIGSSLGAANAAAVTPTT-TVLAA
MUL_1837|M.ulcerans_Agy99           ------MSVVLVVAPEALSAAAANIAGIGSSLGAANAAAATPTT-TVLAA
Mb1476c|M.bovis_AF2122/97           ------MSNVMVVP-GMLSAAAADVASIGAALSAANGAAAPTTA-GVLAA
Rv1441c|M.tuberculosis_H37Rv        ------MSNVMVVP-GMLSAAAADVASIGAALSAANGAAAPTTA-GVLAA
Mflv_5091|M.gilvum_PYR-GCK          QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNG-GNGLG
Mvan_1264|M.vanbaalenii_PYR-1       QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNG-GNGLG
MSMEG_0868|M.smegmatis_MC2_155      DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNG-GVGWA
TH_3810|M.thermoresistible__bu      -------------------------------------------------V
MAB_4284c|M.abscessus_ATCC_199      AAQVGAVMPVVAESVASNYGYQSQWVNTGN----PIHDLSGNLQ-NYYAA
MLBr_01183|M.leprae_Br4923          -------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPP
MAV_4827|M.avium_104                MAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGT
                                                                                      

MMAR_2248|M.marinum_M               --GTDEVSGAIATLFCGYARDYQNLSTQLADFHQQFLQALTGSANSYTAA
MUL_1837|M.ulcerans_Agy99           --GTDEISTTIATLFCGYARDYQNLSTQLASFHQQFLQALTGSANSYTAA
Mb1476c|M.bovis_AF2122/97           --GADEVSAAIASLFSGYARDYQALSAQMARFHQQFVQALTASVGSYAAA
Rv1441c|M.tuberculosis_H37Rv        --GADEVSAAIASLFSGYARDYQALSAQMARFHQQFVQALTASVGSYAAA
Mflv_5091|M.gilvum_PYR-GCK          --GGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATG
Mvan_1264|M.vanbaalenii_PYR-1       --SGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATG
MSMEG_0868|M.smegmatis_MC2_155      --GLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGG
TH_3810|M.thermoresistible__bu      --DGDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGG
MAB_4284c|M.abscessus_ATCC_199      --QPDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVD
MLBr_01183|M.leprae_Br4923          --AADDVSILLAHFFSGHGRQYQAH------------------ASQGATN
MAV_4827|M.avium_104                REGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAA
                                           .                                          

MMAR_2248|M.marinum_M               EAANTNPLQALEQQLLAAINAPTQTLLGRPLIGNGANG------------
MUL_1837|M.ulcerans_Agy99           EAANTNPLQALEQQLLAAINAPTQTLLGRPLIGNGANG------------
Mb1476c|M.bovis_AF2122/97           EAANASPLQALEQQVLAAINAPTQTLLGRPLIGNGADG------------
Rv1441c|M.tuberculosis_H37Rv        EAANASPLQALEQQVLAAINAPTQTLLGRPLIGNGADG------------
Mflv_5091|M.gilvum_PYR-GCK          ATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG------------
Mvan_1264|M.vanbaalenii_PYR-1       ATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG------------
MSMEG_0868|M.smegmatis_MC2_155      GTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGP
TH_3810|M.thermoresistible__bu      GTGIIS--------------------LLSLAGNGGNGG------------
MAB_4284c|M.abscessus_ATCC_199      SFNRGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGP----------I
MLBr_01183|M.leprae_Br4923          HQDLIQSL---------------------LTSSSAYAG------------
MAV_4827|M.avium_104                LAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIPD------------
                                                                      .  .            

MMAR_2248|M.marinum_M               -----APGQNGADGGLLWGN------------------------------
MUL_1837|M.ulcerans_Agy99           -----APGQNGADGGLLWG-------------------------------
Mb1476c|M.bovis_AF2122/97           -----LPGQNGGAGGLLWGN------------------------------
Rv1441c|M.tuberculosis_H37Rv        -----LPGQNGGAGGLLWGN------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG-------------
Mvan_1264|M.vanbaalenii_PYR-1       --AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG-------------
MSMEG_0868|M.smegmatis_MC2_155      NVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTV
TH_3810|M.thermoresistible__bu      ---NGYRTTDNNALDGGHGG------------------------------
MAB_4284c|M.abscessus_ATCC_199      ASGQGSTAVNGDVRDSNIIN------------------------------
MLBr_01183|M.leprae_Br4923          -----TETANHDSL------------------------------------
MAV_4827|M.avium_104                ----VYKQQIRAESYGDAAG------------------------------
                                                                                      

MMAR_2248|M.marinum_M               ----------------------------------------------GGTG
MUL_1837|M.ulcerans_Agy99           ------------------------------------------------TG
Mb1476c|M.bovis_AF2122/97           ----------------------------------------------GGNG
Rv1441c|M.tuberculosis_H37Rv        ----------------------------------------------GGNG
Mflv_5091|M.gilvum_PYR-GCK          ---AVGAAGAAG------TVGTAGATGGTG---------------TGANG
Mvan_1264|M.vanbaalenii_PYR-1       ---AIGTAGVAG------AAGTAGATGGTG---------------VGGNG
MSMEG_0868|M.smegmatis_MC2_155      DGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDG
TH_3810|M.thermoresistible__bu      ---------------------------------------------NGGNV
MAB_4284c|M.abscessus_ATCC_199      -------------------------------------------ADHGSNV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------------------------------------QLSAMVA
                                                                                      

MMAR_2248|M.marinum_M               GTGDATHPAG---------------------GNGGNAGLIG---------
MUL_1837|M.ulcerans_Agy99           GTGDATHPAG---------------------GNGGNAGLIG---------
Mb1476c|M.bovis_AF2122/97           GAGDAAHPNG---------------------GNGGDAGMFG---------
Rv1441c|M.tuberculosis_H37Rv        GAGDAAHPNG---------------------GNGGDAGMFG---------
Mflv_5091|M.gilvum_PYR-GCK          GAGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVG
Mvan_1264|M.vanbaalenii_PYR-1       GAGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIG
MSMEG_0868|M.smegmatis_MC2_155      GHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMG
TH_3810|M.thermoresistible__bu      GFFSLFNLGG--------------------AGGWGGSGVDG---------
MAB_4284c|M.abscessus_ATCC_199      GVDQSQTRVGGDYTN---------------VSGHGSADIDKSVTVVDDHS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GLEKLESLPGGLLLVG---------------SGVDVAPLKQVLQTTTFLD
                                                                                      

MMAR_2248|M.marinum_M               --------------------------------------------------
MUL_1837|M.ulcerans_Agy99           --------------------------------------------------
Mb1476c|M.bovis_AF2122/97           --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG--------
Mvan_1264|M.vanbaalenii_PYR-1       GQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG--------
MSMEG_0868|M.smegmatis_MC2_155      EIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKAS
TH_3810|M.thermoresistible__bu      ------------VDVVGGNP------------------------------
MAB_4284c|M.abscessus_ATCC_199      QRNTTNINDSFNTDRSTNIGSGNTTNTEIGSHN-----------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                VSVAEEPETALARGAALAAANAPLFASSTAALAY----------------
                                                                                      

MMAR_2248|M.marinum_M               -------------------------------------------------N
MUL_1837|M.ulcerans_Agy99           -------------------------------------------------N
Mb1476c|M.bovis_AF2122/97           -------------------------------------------------N
Rv1441c|M.tuberculosis_H37Rv        -------------------------------------------------N
Mflv_5091|M.gilvum_PYR-GCK          -----LQGGKGGDGGAGGKGGDADSMGS------------------AGAT
Mvan_1264|M.vanbaalenii_PYR-1       -----LQGGQGGDGGTGGTGGDATSMGE------------------AGAT
MSMEG_0868|M.smegmatis_MC2_155      GTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASAN
TH_3810|M.thermoresistible__bu      ------------DGGTPG------------------------------AH
MAB_4284c|M.abscessus_ATCC_199      ----------QANIGTS------------------------------TSA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------------------------------------------AQD
                                                                                      

MMAR_2248|M.marinum_M               GGAGGTGYSPASPSGAN---------------------------------
MUL_1837|M.ulcerans_Agy99           GGAGGTGYSPATGTGAG---------------------------------
Mb1476c|M.bovis_AF2122/97           GGAGGAGYSPAAGTGAA---------------------------------
Rv1441c|M.tuberculosis_H37Rv        GGAGGAGYSPAAGTGAA---------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GGKGGNGGNGGRGGLFG---------------KGGNAGNGAD--------
Mvan_1264|M.vanbaalenii_PYR-1       GGKGGNGGNGGRGSLFG---------------RGGNAGNGGN--------
MSMEG_0868|M.smegmatis_MC2_155      GAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDP
TH_3810|M.thermoresistible__bu      GESHTPGVYTDRQ-------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GGSAAVGGNAGLAGNAG---------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PGTGAVDQYSLPDYLYVP--------------------------------
                                                                                      

MMAR_2248|M.marinum_M               -----------------GGAGGIGGRGGSLFGSGGAGG------------
MUL_1837|M.ulcerans_Agy99           -----------------GGAGGSGGRGGFFFGSGGAGG------------
Mb1476c|M.bovis_AF2122/97           -----------------GGAGGAGGAGGWLSGNGGAGG------------
Rv1441c|M.tuberculosis_H37Rv        -----------------GGAGGAGGAGGWLSGNGGAGG------------
Mflv_5091|M.gilvum_PYR-GCK          --------------GGTGGAGGAGGTGG-TGGAGGTGG------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------GGTGGNGGNGGTGG-TGGNGGTGG------------
MSMEG_0868|M.smegmatis_MC2_155      NGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHS
TH_3810|M.thermoresistible__bu      ------------------GEDGEDGTGTGIGGRGGNGG------------
MAB_4284c|M.abscessus_ATCC_199      ----------------LAGNAGLAGNAGLAGNAGLAGN------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------------VDPEPGDDELAYSAVGEEDAESPTVVIEKLFLP-
                                                                                      

MMAR_2248|M.marinum_M               -----DGGAGAGGTSPGG-------QSAGAGGNGGSG----GATGLCGTG
MUL_1837|M.ulcerans_Agy99           -----DGGASAGGTSPGG-------QSAGAGGNGGSG----GATGLCGTG
Mb1476c|M.bovis_AF2122/97           -----NGGTGASGADGGGGLPPVPASPGGNGGGGGAG----GAAGMFGTG
Rv1441c|M.tuberculosis_H37Rv        -----NGGTGASGADGGGGLPPVPASPGGNGGGGDAG----GAAGMFGTG
Mflv_5091|M.gilvum_PYR-GCK          -----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1       -----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155      TGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDG
TH_3810|M.thermoresistible__bu      ----SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNG
MAB_4284c|M.abscessus_ATCC_199      ---AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLA----GNAGLAGNA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --EDSEPRRRPVLLVGSGLAVVGISAVLALEIALAIGIRTTGTVALQPTP
                                                                                      

MMAR_2248|M.marinum_M               GAGGSGGVGGKGGS---------SGATASLGGIG------------GSGG
MUL_1837|M.ulcerans_Agy99           GAGG-----GKGGS---------SGATASLGGIG------------GSGG
Mb1476c|M.bovis_AF2122/97           GAGGTGGDGGAGGAGD----SPNSGANGARGGDG------------GNGA
Rv1441c|M.tuberculosis_H37Rv        GAGGTGGDGGAGGAGD----SPNSGANGARGGDG------------GNGA
Mflv_5091|M.gilvum_PYR-GCK          GKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1       GKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGG
MSMEG_0868|M.smegmatis_MC2_155      GRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGG
TH_3810|M.thermoresistible__bu      GHGGRGGFLGIGGSG-------GWGGHGGNGGD-----------TDADGG
MAB_4284c|M.abscessus_ATCC_199      GLAGNAGLAGNAGLAG----NAGLAGNAGLAGNAG--------LAGNAGL
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                NQHLIVPTEQAPAPPPVQASAPQPKISVPEPVAAPKPLSPPVAAPLPAAP
                                                                                      

MMAR_2248|M.marinum_M               AGGDG-----------GWMYGDGGAGG-----------------------
MUL_1837|M.ulcerans_Agy99           AGGDG-----------GWMYGDGGAGG-----------------------
Mb1476c|M.bovis_AF2122/97           AGGAG-----------GRLFGNGGAGG-----------------------
Rv1441c|M.tuberculosis_H37Rv        AGGAG-----------GRLFGNGGAGG-----------------------
Mflv_5091|M.gilvum_PYR-GCK          TGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG-------
Mvan_1264|M.vanbaalenii_PYR-1       TGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG-------
MSMEG_0868|M.smegmatis_MC2_155      NGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRAT
TH_3810|M.thermoresistible__bu      NGGDG---------------GNGGSAG-----------------------
MAB_4284c|M.abscessus_ATCC_199      AGNAG-------------LAGNAGLAG-----------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PPAAP-----------PLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPV
                                                                                      

MMAR_2248|M.marinum_M               ----------AG---GKGGTGGQGLGIG----------------------
MUL_1837|M.ulcerans_Agy99           ----------AG---GKGGTGGQGLGIG----------------------
Mb1476c|M.bovis_AF2122/97           ----------NGGTAGQGGDGGTALGAG----------------------
Rv1441c|M.tuberculosis_H37Rv        ----------NGGTAGQGGDGGTALGAG----------------------
Mflv_5091|M.gilvum_PYR-GCK          ----------TGGTGGQGG-LGGGGGTG----------------------
Mvan_1264|M.vanbaalenii_PYR-1       ----------TGGTGGQGG-LGGVGGTG----------------------
MSMEG_0868|M.smegmatis_MC2_155      VIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTAT
TH_3810|M.thermoresistible__bu      ----------RGGTGGLRGVFGINGGNG----------------------
MAB_4284c|M.abscessus_ATCC_199      ----------NAAVAGNAAVAGNAAVAG----------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PDPVSPPQLLAPPRLSVPQPVQPPVRVP----------------------
                                                                                      

MMAR_2248|M.marinum_M               ----GIGGDGGGGGDGGAG---GNGGW----------VVGNGGIAGAGGH
MUL_1837|M.ulcerans_Agy99           ----GIGGDGGGGGDGGAG---GNGGW----------VVGNG--------
Mb1476c|M.bovis_AF2122/97           ----GIGGDGGTGGAGGTGGTAGIGGS----------SAGAGGAGGDGGA
Rv1441c|M.tuberculosis_H37Rv        ----GIGGDGGTGGAGGTGGTAGIGGS----------SAGAGGAGGDGGA
Mflv_5091|M.gilvum_PYR-GCK          -GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGF
Mvan_1264|M.vanbaalenii_PYR-1       -GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGF
MSMEG_0868|M.smegmatis_MC2_155      DGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGN
TH_3810|M.thermoresistible__bu      --RAGLGGRGXXXXGGGVGAAVRSG---------------NGVFSGGGGT
MAB_4284c|M.abscessus_ATCC_199      --NAAVGGVLNTGVSGAIGGSSHVG---------GAINESLGGSGSVGGS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -QPPSPPQVGGTVPQSPPQHQTPPGEG-----TPPKPDGPGNYGGGHVPT
                                                                                      

MMAR_2248|M.marinum_M               GGTAGSGGQSSGNA-DGGDGGTGGAGG---------------------TS
MUL_1837|M.ulcerans_Agy99           --------------------------------------------------
Mb1476c|M.bovis_AF2122/97           GGNGGGSSMIGGKGGTGGNGGVGGTGG---------------------AS
Rv1441c|M.tuberculosis_H37Rv        GGTGGGSSMIGGKGGTGGNGGVGGTGG---------------------AS
Mflv_5091|M.gilvum_PYR-GCK          GGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSA
Mvan_1264|M.vanbaalenii_PYR-1       GGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSA
MSMEG_0868|M.smegmatis_MC2_155      GGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYG
TH_3810|M.thermoresistible__bu      PSAGFGVPTTIQFPAGSCTSRAVSREG-----------------------
MAB_4284c|M.abscessus_ATCC_199      TAVGGGAHTGVGGGVSTGVGVGSHVGG--------------------GIS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PGAGGSGGSGGGHVPTPGAGGSGGSGG---------------------GH
                                                                                      

MMAR_2248|M.marinum_M               GRLLGSAGDGGGGGDGGLS-------------------------------
MUL_1837|M.ulcerans_Agy99           -----------GGGDGGLS-------------------------------
Mb1476c|M.bovis_AF2122/97           ALTIGNGSSAGAGGAGGAGGTGGTGGYI-------------ESLDGKGQA
Rv1441c|M.tuberculosis_H37Rv        ALTIGNGSSAGAGGAGGAGGTGGTGGYI-------------ESLDGKGQA
Mflv_5091|M.gilvum_PYR-GCK          GKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAG
Mvan_1264|M.vanbaalenii_PYR-1       GTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQG
MSMEG_0868|M.smegmatis_MC2_155      STLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGG
TH_3810|M.thermoresistible__bu      -IMPSSRAASARAG---------------------------AACASSTSR
MAB_4284c|M.abscessus_ATCC_199      ESLGGSGSVGGSTAVGGGAHTGVGGGVS----------TGVGVGSHVGGG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                VPTPGTGGPGGTGGSGGGHVPTPGAGTP-----------------GGSGG
                                                                                      

MMAR_2248|M.marinum_M               -VGPHSGRGAGGGGG-------------------GGGSALLIGNGGNGGA
MUL_1837|M.ulcerans_Agy99           -VGPHSGRGAGGGGG-------------------GGGSALLIGNGGNGGA
Mb1476c|M.bovis_AF2122/97           GNGGNGGNGAAGGAG-------------------GGGTG-AGGNGGAGGN
Rv1441c|M.tuberculosis_H37Rv        GNGGNGGNGAAGGAG-------------------GGGTG-AGGNGGAGGN
Mflv_5091|M.gilvum_PYR-GCK          ATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAA
Mvan_1264|M.vanbaalenii_PYR-1       SAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAA
MSMEG_0868|M.smegmatis_MC2_155      DGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGAD
TH_3810|M.thermoresistible__bu      SRRSFCCSRA----------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ISESLGGSGSVGGSTAVG---------GGAHTGVGGGVNTGVGVGSHVGG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GHLPFPGAGSTPGGS-------------------GGGHLPTPGAGTPGGG
                                                                                      

MMAR_2248|M.marinum_M               GG------------------------------------------------
MUL_1837|M.ulcerans_Agy99           GG------------------------------------------------
Mb1476c|M.bovis_AF2122/97           GG------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv        GG------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG----
Mvan_1264|M.vanbaalenii_PYR-1       GKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG----
MSMEG_0868|M.smegmatis_MC2_155      GWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSV
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GISESLGGSGSVG-------GSTAVGGGAHTSAINDALGGSGSVGG----
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                LGGFG---------------------------------------------
                                                                                      

MMAR_2248|M.marinum_M               -------------------------------------TGLP------DGT
MUL_1837|M.ulcerans_Agy99           -------------------------------------TGLP------EGT
Mb1476c|M.bovis_AF2122/97           -------------------------------------DGGPSQGGGNPGF
Rv1441c|M.tuberculosis_H37Rv        -------------------------------------DGGPSQGGGNPGF
Mflv_5091|M.gilvum_PYR-GCK          -------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGG
Mvan_1264|M.vanbaalenii_PYR-1       -------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGG
MSMEG_0868|M.smegmatis_MC2_155      WKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------STAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSHGAAG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------------------------------GGHAPAPGGGLGGGGG
                                                                                      

MMAR_2248|M.marinum_M               GGNGGTGG-----------LLFGTPGMHG-
MUL_1837|M.ulcerans_Agy99           GGTGGTGG-----------LLFGTPGMHG-
Mb1476c|M.bovis_AF2122/97           GGDGGTGGPGGVGVPDGIGGANGAQGKHG-
Rv1441c|M.tuberculosis_H37Rv        GGDGGTGGPGGVGVPDGIGGANGAQGKHG-
Mflv_5091|M.gilvum_PYR-GCK          AG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1       AG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155      SGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu      ------------------------------
MAB_4284c|M.abscessus_ATCC_199      TGFEAQGHAQGHASETAHTTLPGAEHH---
MLBr_01183|M.leprae_Br4923          ------------------------------
MAV_4827|M.avium_104                HAPAPGGGLGGFGGGHSGGGLGGLGGGHK-