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M. bovis AF2122 / 97 Mb0857c (PE_PGRS14)

annotation: PE-PGRS family protein
coordinates: 928739 - 931234
length: 831
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 Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0857cPE_PGRS14-100% (831)PE-PGRS family protein
M. bovis AF2122 / 97Mb3537PE_PGRS530.047.43% (972) PE-PGRS family protein
M. bovis AF2122 / 97Mb3543PE_PGRS570.047.97% (934) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_5091-1e-13946.07% (738) triple helix repeat-containing collagen
M. tuberculosis H37RvRv0834cPE_PGRS140.094.22% (882) PE-PGRS family protein
M. leprae Br4923MLBr_01183-5e-1440.62% (96) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-2e-4836.14% (487) hypothetical protein MAB_4284c
M. marinum MMMAR_0492-0.055.76% (868) PE-PGRS family protein
M. avium 104MAV_4827-4e-2441.27% (189) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-1e-12040.62% (810) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-1e-4139.61% (308) PUTATIVE -
M. ulcerans Agy99MUL_0572-0.049.34% (906) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-1e-13543.98% (764) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Mb0857c|M.bovis_AF2122/97           --------------------------------------------------
Rv0834c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0492|M.marinum_M               --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb0857c|M.bovis_AF2122/97           --------------------------------------------------
Rv0834c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0492|M.marinum_M               --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb0857c|M.bovis_AF2122/97           ---------------------------------------MSFVI-AAPDL
Rv0834c|M.tuberculosis_H37Rv        ---------------------------------------MSFVI-AAPDL
MMAR_0492|M.marinum_M               ---------------------------------------MSGVI-AALDT
MLBr_01183|M.leprae_Br4923          ---------------------------------------MPLFLNAEPQA
MUL_0572|M.ulcerans_Agy99           ---------------------------------------MSYVV-AIPDM
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------MSIIDFILNLFRDP
MAV_4827|M.avium_104                -------------------------------------MNIVLGVSMAPSS
                                                                                      

Mb0857c|M.bovis_AF2122/97           ------------------------------------------VAMATEDL
Rv0834c|M.tuberculosis_H37Rv        ------------------------------------------VAMATEDL
MMAR_0492|M.marinum_M               ------------------------------------------LTAAATDV
MLBr_01183|M.leprae_Br4923          ------------------------------------------LTAAANTL
MUL_0572|M.ulcerans_Agy99           ------------------------------------------LASAAADV
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      ------------------------------------------VDGDGGSG
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------------VEAASYVA
MAV_4827|M.avium_104                ------------------------------------------IQMVVLEG
                                                                              :       

Mb0857c|M.bovis_AF2122/97           AG---------------------------------------IGASLTAAN
Rv0834c|M.tuberculosis_H37Rv        AG---------------------------------------IGASLTAAN
MMAR_0492|M.marinum_M               AG---------------------------------------LGAAINAAN
MLBr_01183|M.leprae_Br4923          EG---------------------------------------LSAATVASN
MUL_0572|M.ulcerans_Agy99           AG---------------------------------------IGSSVGAAN
Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1       S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu      GR----------------------------------------TGLFSKLS
MAB_4284c|M.abscessus_ATCC_199      DP---------------------------------------EAALANAGL
MAV_4827|M.avium_104                EY--------------------------------------ADGATVEEDA
                                                                                      

Mb0857c|M.bovis_AF2122/97           AAAAVPTSGLLAAAGDEVSAAIAALFSSHGQQYQAMSAQAAAFHARFVQA
Rv0834c|M.tuberculosis_H37Rv        AAAAVPTSGLLAAAGDEVSAAIAALFSSHGQQYQAMSAQAAAFHARFVQA
MMAR_0492|M.marinum_M               AAAAVSTTRLMAAAGDEVSAAIAALFSDHALQYQAVSAEAVAFHGRFVQA
MLBr_01183|M.leprae_Br4923          AAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQS
MUL_0572|M.ulcerans_Agy99           TAAVGATTGVMAAADDEVSVAIAALFSGHGQAYQAISAQAAAFHDQFLRA
Mflv_5091|M.gilvum_PYR-GCK          QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1       QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155      DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu      RGGDGGDGGLGGNGGHGGGTGIISLLSLAGNGGNGGNGYRTTDN-NALDG
MAB_4284c|M.abscessus_ATCC_199      SAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQ
MAV_4827|M.avium_104                IDVTGADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAA
                                                                                      

Mb0857c|M.bovis_AF2122/97           LAGAMGAYAAAEAANASPLQTLEQGLLGAINAPAAALSGRPFIGNGTNGA
Rv0834c|M.tuberculosis_H37Rv        LAGAMGAYAAAEAANASPLQTLEQGLLGAINAPAAALSGRPFIGNGTNGA
MMAR_0492|M.marinum_M               LTGGVQMYAAAETANTASLQTLGQDLLGMVNAPAAAVLGRPLIGNGTNGA
MLBr_01183|M.leprae_Br4923          LLTSSSAYAGTETANHDSL-------------------------------
MUL_0572|M.ulcerans_Agy99           LTGAGGAYAAAEAANASPLQAAEQEVLAVINAPTNALLGRPLIGNGTDGL
Mflv_5091|M.gilvum_PYR-GCK          GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1       GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155      LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu      GHGGNGGNVGFFSLFNLG--------------------------------
MAB_4284c|M.abscessus_ATCC_199      PDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN
MAV_4827|M.avium_104                ALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTAT
                                                                                      

Mb0857c|M.bovis_AF2122/97           PGTGEAGGPGGWLLGNGGNGGSGAPGQTGGAGGAAG-----------LLG
Rv0834c|M.tuberculosis_H37Rv        PGTGEAGGPGGWLLGNGGNGGSGAPGQTGGAGGAAG-----------LLG
MMAR_0492|M.marinum_M               PGSGDAGGPGGLLFGNGGNGGSGSAGMAGGAGGSAG-----------LIG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           AGTGAAGGAGGLLWGNGGNGGSGAAGQAGGAGGAAG-----------LIG
Mflv_5091|M.gilvum_PYR-GCK          VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1       VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155      GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu      --------------GAGGWGGSGVDGVDVVGGNPDG--------------
MAB_4284c|M.abscessus_ATCC_199      RGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGP----------IASG
MAV_4827|M.avium_104                LAVVETSDGSIPDVYKQQIRAESYGDAAGQLSAMVAG-------------
                                                                                      

Mb0857c|M.bovis_AF2122/97           HGGTGGAGGTG-ASGGKGGTGGWLWGSGGAGGAGGSGGGSGGAGGNALMF
Rv0834c|M.tuberculosis_H37Rv        HGGTGGAGGTG-ASGGKGGTGGWLWGSGGAGGAGGSGGGSGGAGGNALMF
MMAR_0492|M.marinum_M               NGGAGGAGGAD-AAGGPGGAGGWLWGGGGAG-------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           TGGAGGMGGAGGGAGGMGGSGGWLLGNGGAGGAGGVGCAG----------
Mflv_5091|M.gilvum_PYR-GCK          VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1       VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155      VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      QGSTAVNGDVRDSNIINADHGSNVGVDQSQTRVG----------------
MAV_4827|M.avium_104                ------------LEKLESLPGGLLLVGSGVDVAP----------------
                                                                                      

Mb0857c|M.bovis_AF2122/97           GIGGNGGAGGAASGVGNGGVGGAGGAGGALVAIG--------GAGGAGGA
Rv0834c|M.tuberculosis_H37Rv        GIGGNGGAGGAASGVGNGGVGGAGGAGGALVAIG--------GAGGAGGA
MMAR_0492|M.marinum_M               ------GLGGAASGAGNGGAGGAGGAGGAFIAIG--------GVGGDGGA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           VSGGVGGTGGNAMLFGNGGAGGMGGAG-ADGAVG--------AAGTAGTS
Mflv_5091|M.gilvum_PYR-GCK          AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1       AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155      AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------------------------------GDY
MAV_4827|M.avium_104                -------------------------------------------LKQVLQT
                                                                                      

Mb0857c|M.bovis_AF2122/97           ATTGTGGAGGAGSNALGLFLGLGGSGGQ-GGDSAMGSGGAGGAGGSGGAA
Rv0834c|M.tuberculosis_H37Rv        ATTGTGGAGGAGSNALGLFLGLGGSGGQ-GGDSAMGSGGAGGAGGSGGAA
MMAR_0492|M.marinum_M               ASSGTGGVGGAGGNADGLIVSLGGAGGH-GGDATTGIGGAGGAGGMATAR
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           TSAGGVGGAGWDATAAGVLAATGGDGGDSGGGGAGGNGGAGGAGGHGSAL
Mflv_5091|M.gilvum_PYR-GCK          GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ-
Mvan_1264|M.vanbaalenii_PYR-1       QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ-
MSMEG_0868|M.smegmatis_MC2_155      TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      TNVSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTTNTE
MAV_4827|M.avium_104                TTFLDVSVAEEPETALARGAALAAANAPLFASSTAALAYAQDPGTGAVDQ
                                                                                      

Mb0857c|M.bovis_AF2122/97           SPFGIDIGIGGAGGHGGAGTNGGAGGAGGAGGSSGTVFALD---------
Rv0834c|M.tuberculosis_H37Rv        SPFGIDIGIGGAGGHGGAGTNGGAGGAGGAGGSSGTVFALD---------
MMAR_0492|M.marinum_M               IPAGINFNVGGAGGHGGAGATGGAGGGGGSAYSG--YVGIA---------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           FGADGANGNGGAGGAGGNPGAPGNGGTGGVGPDAATSGGMG---------
Mflv_5091|M.gilvum_PYR-GCK          ---GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG---------
Mvan_1264|M.vanbaalenii_PYR-1       ---GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG---------
MSMEG_0868|M.smegmatis_MC2_155      S--GADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASG
TH_3810|M.thermoresistible__bu      ---GTPGAHGESHTPGVYTDRQGEDGEDGTG-------------------
MAB_4284c|M.abscessus_ATCC_199      IGSHNQANIGTSTSAGGSAAVGGNAGLAGNAG------------------
MAV_4827|M.avium_104                YSLPDYLYVPVDPEPGDDELAYSAVGEEDAESPTVVIEKLFLP-------
                                                                                      

Mb0857c|M.bovis_AF2122/97           ---------LSWGGAGGNGGAATTGTGG-----------------AGGTG
Rv0834c|M.tuberculosis_H37Rv        ---------LSWGGAGGNGGAATTGTGG-----------------AGGTG
MMAR_0492|M.marinum_M               ---------FGQGGAGGIGGAASTGMAG-----------------AGGSG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           ---------GTGGDPGAVGGRGNSGAAGG---------------AGAVAG
Mflv_5091|M.gilvum_PYR-GCK          ----LQGGKGGDGGAGGKGGDADSMGS------------------AGATG
Mvan_1264|M.vanbaalenii_PYR-1       ----LQGGQGGDGGTGGTGGDATSMGE------------------AGATG
MSMEG_0868|M.smegmatis_MC2_155      TAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------LAGNAGLAGNAGLAGNAG----------------------
MAV_4827|M.avium_104                --------------EDSEPRRRPVLLVG----------------------
                                                                                      

Mb0857c|M.bovis_AF2122/97           GFAVAPDFIGFGAAYGGAGGLGGAATG-AGGTGGTGGVGAGG--------
Rv0834c|M.tuberculosis_H37Rv        GFAVAPDFIGFGAAYGGAGGLGGAATG-AGGTGGTGGVGAGG--------
MMAR_0492|M.marinum_M               GSCVAFDFVGFAAAHGGAGGTGGAATG-VGATAGAAGSGGLG--------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           ASGAAGTIIAGNGGNGGAGGAGYAADGPAGPAIGNGGDGGHG--------
Mflv_5091|M.gilvum_PYR-GCK          GKGGNGGNGGRGGLFG---------------KGGNAGNGAD---------
Mvan_1264|M.vanbaalenii_PYR-1       GKGGNGGNGGRGSLFG---------------RGGNAGNGGN---------
MSMEG_0868|M.smegmatis_MC2_155      AVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPN
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------------------LAGNAGLAGN---------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb0857c|M.bovis_AF2122/97           -----------FAALGVGVGGAGGAGGAATETGGIGGAGGLG--------
Rv0834c|M.tuberculosis_H37Rv        -----------FAALGVGVGGAGGAGGAATETGGIGGAGGLG--------
MMAR_0492|M.marinum_M               -----------VAIVGSGVGGVGGVGGAATGAG-----------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           -----------GAGGFYGNGGAGGAGGNSAPGGGTGGNGGTGG-------
Mflv_5091|M.gilvum_PYR-GCK          -------------GGTGGAGGAGGTGG-TGGAGGTGG-------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------GGTGGNGGNGGTGG-TGGNGGTGG-------------
MSMEG_0868|M.smegmatis_MC2_155      GPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHST
TH_3810|M.thermoresistible__bu      ----------------TGIGGRGGNGGSSSGTHPMAE-------------
MAB_4284c|M.abscessus_ATCC_199      -------------AGLAGNAGLAGNAGLAGNAGLAGN-------------
MAV_4827|M.avium_104                ----------------SGLAVVGISAVLALEIALAIG-------------
                                                                                      

Mb0857c|M.bovis_AF2122/97           -----VGLLGGAGGAGGPGGAASAGSGGHGGTGGDALGLIGAGIGGVGGV
Rv0834c|M.tuberculosis_H37Rv        -----VGLLGGAGGAGGPGGAASAGSGGHGGTGGDALGLIGAGIGGVGGV
MMAR_0492|M.marinum_M               ---------------------ATAAAGGAGGLG---LAAVGSGTGGAGGA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           ----DSGAMGSSGGRGGDGGVGTNGGAGGGGGNATSYGTANATGGAGGDG
Mflv_5091|M.gilvum_PYR-GCK          ----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1       ----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155      GQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGG
TH_3810|M.thermoresistible__bu      ---------------DGEHVKALDGRPGLDGGNGSHGGNGGHGGRGGFLG
MAB_4284c|M.abscessus_ATCC_199      --------------AGLAGNAGLAGNAGLAGNAG----LAGNAGLAGNAG
MAV_4827|M.avium_104                --------------IRTTGTVALQPTPNQHLIVPTEQAPAPPPVQASAPQ
                                                                                      

Mb0857c|M.bovis_AF2122/97           GGAATDTGGNGGAGGS--GTGLLGGVGGAGGHGGG-------ASVGTGGS
Rv0834c|M.tuberculosis_H37Rv        GGAATDTGGNGGAGGS--GTGLLGGVGGAGGHGGG-------ASVGTGGS
MMAR_0492|M.marinum_M               GGVGAGTGGAGGAGAH--GFGLLSGTAGAGGAGGA-------ASAGTGGA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           GTGSTGNGGSGGDGGN--GGTGHGGGGGPGGTAIN-------YGAGDAFG
Mflv_5091|M.gilvum_PYR-GCK          KGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1       KGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155      RGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGN
TH_3810|M.thermoresistible__bu      IGGSGGWGGHGGNGGDTDADGGNGGDGGNGGS------------AGRGGT
MAB_4284c|M.abscessus_ATCC_199      LAGNAGLAGNAGLAGN-AGLAGNAGLAGNAGLAGN--------AAVAGNA
MAV_4827|M.avium_104                PKISVPEPVAAPKPLSPPVAAPLPAAPPPAAPPLP---------EAPPIP
                                                                                      

Mb0857c|M.bovis_AF2122/97           GGAG----------GDGFGFVGAGGNGGNAGTGVGVNGANGG--------
Rv0834c|M.tuberculosis_H37Rv        GGAG----------GDGFGFVGAGGNGGNAGTGVGVNGANGG--------
MMAR_0492|M.marinum_M               GGLG----------GTGFGLIAAGGDGGGAGTGVGSNGGDGG--------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           GAAG----------KGGTGVVGGNGGSGGAAYNYGTGNATGA--------
Mflv_5091|M.gilvum_PYR-GCK          GGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG--------
Mvan_1264|M.vanbaalenii_PYR-1       GGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG--------
MSMEG_0868|M.smegmatis_MC2_155      GGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATV
TH_3810|M.thermoresistible__bu      GGLR---------------------------GVFGINGGNGR--------
MAB_4284c|M.abscessus_ATCC_199      AVAG--------------------------NAAVAGNAAVGG--------
MAV_4827|M.avium_104                AAPP----------------------------VVPVPVVVPP--------
                                                                                      

Mb0857c|M.bovis_AF2122/97           ----------NGGSATGALAAVG---------------------------
Rv0834c|M.tuberculosis_H37Rv        ----------NGGSATGALAAVG---------------------------
MMAR_0492|M.marinum_M               ----------GGGGAHAVLAAIA---------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           ----------GGSSGSGGAASVPNSASTA-----------------TATS
Mflv_5091|M.gilvum_PYR-GCK          ---------TGGTGGQGG-LGGGGGTG-----------------------
Mvan_1264|M.vanbaalenii_PYR-1       ---------TGGTGGQGG-LGGVGGTG-----------------------
MSMEG_0868|M.smegmatis_MC2_155      IGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATD
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------------------VL
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb0857c|M.bovis_AF2122/97           GAGAAGGDATSGTGGFGGAGGSARG--LIFALGGAGAAGGDASTGVGGPG
Rv0834c|M.tuberculosis_H37Rv        GAGAAGGDATSGTGGFGGAGGSARG--LIFALGGAGAAGGDASTGVGGPG
MMAR_0492|M.marinum_M               GSGGQGQAGTSGFGGFGGSGGSAES--LFFSIGGAGGAGGDASTGGGGLG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           GSGGAGGDGTDGGNGGSGGFAFTFG--TGNIIAGVGGGGGTGSTGVGGIG
Mflv_5091|M.gilvum_PYR-GCK          GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFG
Mvan_1264|M.vanbaalenii_PYR-1       GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFG
MSMEG_0868|M.smegmatis_MC2_155      GHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNG
TH_3810|M.thermoresistible__bu      --AGLGGRGXXXXGGGVG---------------AAVRSGNGVFSGGGGTP
MAB_4284c|M.abscessus_ATCC_199      NTGVSGAIGGSSHVGGAINESLGGS----GSVGGSTAVGGGAHTGVGGGV
MAV_4827|M.avium_104                --VPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVG
                                                                                      

Mb0857c|M.bovis_AF2122/97           GPGGTGTASSPFGIAIAIGGAGAQGGAGTSG-ATGGAGGDGVFEGIAVLG
Rv0834c|M.tuberculosis_H37Rv        GPGGTGTASSPFGIAIAIGGAGAQGGAGTSG-ATGGAGGDGVFEGIAVLG
MMAR_0492|M.marinum_M               GNGGVAVAHSPIGIDIGIGGAGGHGGSGTSG-ADGGAGGVSISEGIFAID
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           GSGGGADINNGAFTVVPQGGAGGHGGDGATDGGAGGAGGFTEIDSSASVI
Mflv_5091|M.gilvum_PYR-GCK          GSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAG
Mvan_1264|M.vanbaalenii_PYR-1       GVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAG
MSMEG_0868|M.smegmatis_MC2_155      GDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGS
TH_3810|M.thermoresistible__bu      SAGFGVPTTIQFPAGSCTSRAVSREGIMPSSRAASARAGAACASSTSRSR
MAB_4284c|M.abscessus_ATCC_199      STGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGS
MAV_4827|M.avium_104                GTVPQSPPQHQTPPGEGTPPKPDGPGNYGGGHVPTPGAGGSGGSGGGHVP
                                                                                      

Mb0857c|M.bovis_AF2122/97           LGFGGAAGAGG-AATGDGATGGAGGFGGAG-AGIANFLGFSVLHGGAGGA
Rv0834c|M.tuberculosis_H37Rv        LGFGGAAGAGG-AATGDGATGGAGGFGGAG-AGIANFLGFSVLHGGAGGA
MMAR_0492|M.marinum_M               VNLGGAGGDGGTATTGTAGSGGNGGFVEN-----FDFFGFGVAHGGDGGS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           AATGGAGGDGGSGGTGRGGTGG-GGTGGGG-TGGGGGVGINNGSGEAIGG
Mflv_5091|M.gilvum_PYR-GCK          KAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGA
Mvan_1264|M.vanbaalenii_PYR-1       TAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGS
MSMEG_0868|M.smegmatis_MC2_155      TLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGD
TH_3810|M.thermoresistible__bu      RSFCCSRA------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      HVGGGISESLGGSGSVGGSTAVGGGAHTG--VGGGVNTGVGVGSHVGGGI
MAV_4827|M.avium_104                TPGAGGSGGSGGGHVPTPGTGGPGGTGGSG--------GGHVPTPGAGTP
                                                                                      

Mb0857c|M.bovis_AF2122/97           GGTATGTGGNGGAGGGGGLSSPVILGIGIG--------------------
Rv0834c|M.tuberculosis_H37Rv        GGTATGTGGNGGAGGGGGLSSPVILGIGIGGAGGDGGGALGVLGGMGGDG
MMAR_0492|M.marinum_M               GGAASGAGGIGGAGGNGGSGTTPLFGAYSGGAGGDGGAATG-TGGAGGNG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           APGAGGTGAVGGDGGQGGAAYSYGTGDATGSAGAAGTAGTTGVGGTGGAG
Mflv_5091|M.gilvum_PYR-GCK          TGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAG
Mvan_1264|M.vanbaalenii_PYR-1       AGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAG
MSMEG_0868|M.smegmatis_MC2_155      GGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      SESLGGSGSVGGSTAVGG--------------------------------
MAV_4827|M.avium_104                GGSGGGHLPFPGAG------------------------------------
                                                                                      

Mb0857c|M.bovis_AF2122/97           ----------------------------GAGGNGGDALGLVGVGGNGGNA
Rv0834c|M.tuberculosis_H37Rv        GDGGEAVAVGIAVGGAGGAGGAAPTGNGGAGGNGGDALGLVGVGGNGGNA
MMAR_0492|M.marinum_M               GAGGAASGLGVGIGGAGGHGGAAPTGNGGSGGAGAGGLGLIGAGGNGGDA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           GAAYTLN------------GASTATATGGIGGNGGDGGTANGSNGGNGGA
Mflv_5091|M.gilvum_PYR-GCK          KAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-----
Mvan_1264|M.vanbaalenii_PYR-1       KAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-----
MSMEG_0868|M.smegmatis_MC2_155      WVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVW
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------GAHTSAINDALGGSGSVGGSTAVGGGAHTSA
MAV_4827|M.avium_104                ------------------------STPGGSGGGHLPTPGAGTPGG-----
                                                                                      

Mb0857c|M.bovis_AF2122/97           G-----TGFGANTGGNGGDTTIVVN----GMLAPSTLGYGGNG---VNGG
Rv0834c|M.tuberculosis_H37Rv        G-----TGFGANTGGNGGDTTIVVN----GMLAPSTLGYGGNGGNGVNGG
MMAR_0492|M.marinum_M               G-----AGVAAADGGDGGNAGLVIN----GTYEASPYGNGGNGGNGVNGG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           GGYASTTGTGTASVGNGGRGGDGTA----TVATGGTGGVGGNAHAPAGSP
Mflv_5091|M.gilvum_PYR-GCK          ------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGA
Mvan_1264|M.vanbaalenii_PYR-1       ------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGA
MSMEG_0868|M.smegmatis_MC2_155      KSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGS
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      IN-------ESMNSSINASHSSSMN-----ESFGSSMGSHGAAGTGFEAQ
MAV_4827|M.avium_104                -----------GLGGFGGGHAPAPG--------GGLGGGGGHAPAPGGGL
                                                                                      

Mb0857c|M.bovis_AF2122/97           A-GGTGGKAG--VFG-APGQNGLP-----
Rv0834c|M.tuberculosis_H37Rv        A-GGTGGKAG--VFG-APGQNGLP-----
MMAR_0492|M.marinum_M               S-GGKGGSAG--QVGGTPGQNGSP-----
MLBr_01183|M.leprae_Br4923          -----------------------------
MUL_0572|M.ulcerans_Agy99           V-PGVGGKGGNPGPGGKPGPNGADGIVV-
Mflv_5091|M.gilvum_PYR-GCK          G--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1       G--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155      GNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu      -----------------------------
MAB_4284c|M.abscessus_ATCC_199      G--HAQGHASETAHTTLPGAEHH------
MAV_4827|M.avium_104                G--GFGGGHSGGGLGGLGGGHK-------