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MSFVIAAPDLVAMATEDLAGIGASLTAANAAAAVPTSGLLAAAGDEVSAAIAALFSSHGQQYQAMSAQAA AFHARFVQALAGAMGAYAAAEAANASPLQTLEQGLLGAINAPAAALSGRPFIGNGTNGAPGTGEAGGPGG WLLGNGGNGGSGAPGQTGGAGGAAGLLGHGGTGGAGGTGASGGKGGTGGWLWGSGGAGGAGGSGGGSGGA GGNALMFGIGGNGGAGGAASGVGNGGVGGAGGAGGALVAIGGAGGAGGAATTGTGGAGGAGSNALGLFLG LGGSGGQGGDSAMGSGGAGGAGGSGGAASPFGIDIGIGGAGGHGGAGTNGGAGGAGGAGGSSGTVFALDL SWGGAGGNGGAATTGTGGAGGTGGFAVAPDFIGFGAAYGGAGGLGGAATGAGGTGGTGGVGAGGFAALGV GVGGAGGAGGAATETGGIGGAGGLGVGLLGGAGGAGGPGGAASAGSGGHGGTGGDALGLIGAGIGGVGGV GGAATDTGGNGGAGGSGTGLLGGVGGAGGHGGGASVGTGGSGGAGGDGFGFVGAGGNGGNAGTGVGVNGA NGGNGGSATGALAAVGGAGAAGGDATSGTGGFGGAGGSARGLIFALGGAGAAGGDASTGVGGPGGPGGTG TASSPFGIAIAIGGAGAQGGAGTSGATGGAGGDGVFEGIAVLGLGFGGAAGAGGAATGDGATGGAGGFGG AGAGIANFLGFSVLHGGAGGAGGTATGTGGNGGAGGGGGLSSPVILGIGIGGAGGNGGDALGLVGVGGNG GNAGTGFGANTGGNGGDTTIVVNGMLAPSTLGYGGNGVNGGAGGTGGKAGVFGAPGQNGLP
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0857c | PE_PGRS14 | - | 100% (831) | PE-PGRS family protein |
M. bovis AF2122 / 97 | Mb3537 | PE_PGRS53 | 0.0 | 47.43% (972) | PE-PGRS family protein |
M. bovis AF2122 / 97 | Mb3543 | PE_PGRS57 | 0.0 | 47.97% (934) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_5091 | - | 1e-139 | 46.07% (738) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv0834c | PE_PGRS14 | 0.0 | 94.22% (882) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 5e-14 | 40.62% (96) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 2e-48 | 36.14% (487) | hypothetical protein MAB_4284c |
M. marinum M | MMAR_0492 | - | 0.0 | 55.76% (868) | PE-PGRS family protein |
M. avium 104 | MAV_4827 | - | 4e-24 | 41.27% (189) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-120 | 40.62% (810) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 1e-41 | 39.61% (308) | PUTATIVE - |
M. ulcerans Agy99 | MUL_0572 | - | 0.0 | 49.34% (906) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-135 | 43.98% (764) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment Mb0857c|M.bovis_AF2122/97 -------------------------------------------------- Rv0834c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0492|M.marinum_M -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb0857c|M.bovis_AF2122/97 -------------------------------------------------- Rv0834c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0492|M.marinum_M -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP-- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb0857c|M.bovis_AF2122/97 ---------------------------------------MSFVI-AAPDL Rv0834c|M.tuberculosis_H37Rv ---------------------------------------MSFVI-AAPDL MMAR_0492|M.marinum_M ---------------------------------------MSGVI-AALDT MLBr_01183|M.leprae_Br4923 ---------------------------------------MPLFLNAEPQA MUL_0572|M.ulcerans_Agy99 ---------------------------------------MSYVV-AIPDM Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP MAV_4827|M.avium_104 -------------------------------------MNIVLGVSMAPSS Mb0857c|M.bovis_AF2122/97 ------------------------------------------VAMATEDL Rv0834c|M.tuberculosis_H37Rv ------------------------------------------VAMATEDL MMAR_0492|M.marinum_M ------------------------------------------LTAAATDV MLBr_01183|M.leprae_Br4923 ------------------------------------------LTAAANTL MUL_0572|M.ulcerans_Agy99 ------------------------------------------LASAAADV Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu ------------------------------------------VDGDGGSG MAB_4284c|M.abscessus_ATCC_199 ------------------------------------------VEAASYVA MAV_4827|M.avium_104 ------------------------------------------IQMVVLEG : Mb0857c|M.bovis_AF2122/97 AG---------------------------------------IGASLTAAN Rv0834c|M.tuberculosis_H37Rv AG---------------------------------------IGASLTAAN MMAR_0492|M.marinum_M AG---------------------------------------LGAAINAAN MLBr_01183|M.leprae_Br4923 EG---------------------------------------LSAATVASN MUL_0572|M.ulcerans_Agy99 AG---------------------------------------IGSSVGAAN Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA TH_3810|M.thermoresistible__bu GR----------------------------------------TGLFSKLS MAB_4284c|M.abscessus_ATCC_199 DP---------------------------------------EAALANAGL MAV_4827|M.avium_104 EY--------------------------------------ADGATVEEDA Mb0857c|M.bovis_AF2122/97 AAAAVPTSGLLAAAGDEVSAAIAALFSSHGQQYQAMSAQAAAFHARFVQA Rv0834c|M.tuberculosis_H37Rv AAAAVPTSGLLAAAGDEVSAAIAALFSSHGQQYQAMSAQAAAFHARFVQA MMAR_0492|M.marinum_M AAAAVSTTRLMAAAGDEVSAAIAALFSDHALQYQAVSAEAVAFHGRFVQA MLBr_01183|M.leprae_Br4923 AAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQS MUL_0572|M.ulcerans_Agy99 TAAVGATTGVMAAADDEVSVAIAALFSGHGQAYQAISAQAAAFHDQFLRA Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG TH_3810|M.thermoresistible__bu RGGDGGDGGLGGNGGHGGGTGIISLLSLAGNGGNGGNGYRTTDN-NALDG MAB_4284c|M.abscessus_ATCC_199 SAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQ MAV_4827|M.avium_104 IDVTGADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAA Mb0857c|M.bovis_AF2122/97 LAGAMGAYAAAEAANASPLQTLEQGLLGAINAPAAALSGRPFIGNGTNGA Rv0834c|M.tuberculosis_H37Rv LAGAMGAYAAAEAANASPLQTLEQGLLGAINAPAAALSGRPFIGNGTNGA MMAR_0492|M.marinum_M LTGGVQMYAAAETANTASLQTLGQDLLGMVNAPAAAVLGRPLIGNGTNGA MLBr_01183|M.leprae_Br4923 LLTSSSAYAGTETANHDSL------------------------------- MUL_0572|M.ulcerans_Agy99 LTGAGGAYAAAEAANASPLQAAEQEVLAVINAPTNALLGRPLIGNGTDGL Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG TH_3810|M.thermoresistible__bu GHGGNGGNVGFFSLFNLG-------------------------------- MAB_4284c|M.abscessus_ATCC_199 PDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN MAV_4827|M.avium_104 ALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTAT Mb0857c|M.bovis_AF2122/97 PGTGEAGGPGGWLLGNGGNGGSGAPGQTGGAGGAAG-----------LLG Rv0834c|M.tuberculosis_H37Rv PGTGEAGGPGGWLLGNGGNGGSGAPGQTGGAGGAAG-----------LLG MMAR_0492|M.marinum_M PGSGDAGGPGGLLFGNGGNGGSGSAGMAGGAGGSAG-----------LIG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 AGTGAAGGAGGLLWGNGGNGGSGAAGQAGGAGGAAG-----------LIG Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT TH_3810|M.thermoresistible__bu --------------GAGGWGGSGVDGVDVVGGNPDG-------------- MAB_4284c|M.abscessus_ATCC_199 RGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGP----------IASG MAV_4827|M.avium_104 LAVVETSDGSIPDVYKQQIRAESYGDAAGQLSAMVAG------------- Mb0857c|M.bovis_AF2122/97 HGGTGGAGGTG-ASGGKGGTGGWLWGSGGAGGAGGSGGGSGGAGGNALMF Rv0834c|M.tuberculosis_H37Rv HGGTGGAGGTG-ASGGKGGTGGWLWGSGGAGGAGGSGGGSGGAGGNALMF MMAR_0492|M.marinum_M NGGAGGAGGAD-AAGGPGGAGGWLWGGGGAG------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 TGGAGGMGGAGGGAGGMGGSGGWLLGNGGAGGAGGVGCAG---------- Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG---------------- Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG---------------- MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 QGSTAVNGDVRDSNIINADHGSNVGVDQSQTRVG---------------- MAV_4827|M.avium_104 ------------LEKLESLPGGLLLVGSGVDVAP---------------- Mb0857c|M.bovis_AF2122/97 GIGGNGGAGGAASGVGNGGVGGAGGAGGALVAIG--------GAGGAGGA Rv0834c|M.tuberculosis_H37Rv GIGGNGGAGGAASGVGNGGVGGAGGAGGALVAIG--------GAGGAGGA MMAR_0492|M.marinum_M ------GLGGAASGAGNGGAGGAGGAGGAFIAIG--------GVGGDGGA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 VSGGVGGTGGNAMLFGNGGAGGMGGAG-ADGAVG--------AAGTAGTS Mflv_5091|M.gilvum_PYR-GCK AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG Mvan_1264|M.vanbaalenii_PYR-1 AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -----------------------------------------------GDY MAV_4827|M.avium_104 -------------------------------------------LKQVLQT Mb0857c|M.bovis_AF2122/97 ATTGTGGAGGAGSNALGLFLGLGGSGGQ-GGDSAMGSGGAGGAGGSGGAA Rv0834c|M.tuberculosis_H37Rv ATTGTGGAGGAGSNALGLFLGLGGSGGQ-GGDSAMGSGGAGGAGGSGGAA MMAR_0492|M.marinum_M ASSGTGGVGGAGGNADGLIVSLGGAGGH-GGDATTGIGGAGGAGGMATAR MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 TSAGGVGGAGWDATAAGVLAATGGDGGDSGGGGAGGNGGAGGAGGHGSAL Mflv_5091|M.gilvum_PYR-GCK GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ- Mvan_1264|M.vanbaalenii_PYR-1 QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ- MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 TNVSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTTNTE MAV_4827|M.avium_104 TTFLDVSVAEEPETALARGAALAAANAPLFASSTAALAYAQDPGTGAVDQ Mb0857c|M.bovis_AF2122/97 SPFGIDIGIGGAGGHGGAGTNGGAGGAGGAGGSSGTVFALD--------- Rv0834c|M.tuberculosis_H37Rv SPFGIDIGIGGAGGHGGAGTNGGAGGAGGAGGSSGTVFALD--------- MMAR_0492|M.marinum_M IPAGINFNVGGAGGHGGAGATGGAGGGGGSAYSG--YVGIA--------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 FGADGANGNGGAGGAGGNPGAPGNGGTGGVGPDAATSGGMG--------- Mflv_5091|M.gilvum_PYR-GCK ---GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG--------- Mvan_1264|M.vanbaalenii_PYR-1 ---GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG--------- MSMEG_0868|M.smegmatis_MC2_155 S--GADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASG TH_3810|M.thermoresistible__bu ---GTPGAHGESHTPGVYTDRQGEDGEDGTG------------------- MAB_4284c|M.abscessus_ATCC_199 IGSHNQANIGTSTSAGGSAAVGGNAGLAGNAG------------------ MAV_4827|M.avium_104 YSLPDYLYVPVDPEPGDDELAYSAVGEEDAESPTVVIEKLFLP------- Mb0857c|M.bovis_AF2122/97 ---------LSWGGAGGNGGAATTGTGG-----------------AGGTG Rv0834c|M.tuberculosis_H37Rv ---------LSWGGAGGNGGAATTGTGG-----------------AGGTG MMAR_0492|M.marinum_M ---------FGQGGAGGIGGAASTGMAG-----------------AGGSG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 ---------GTGGDPGAVGGRGNSGAAGG---------------AGAVAG Mflv_5091|M.gilvum_PYR-GCK ----LQGGKGGDGGAGGKGGDADSMGS------------------AGATG Mvan_1264|M.vanbaalenii_PYR-1 ----LQGGQGGDGGTGGTGGDATSMGE------------------AGATG MSMEG_0868|M.smegmatis_MC2_155 TAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----------LAGNAGLAGNAGLAGNAG---------------------- MAV_4827|M.avium_104 --------------EDSEPRRRPVLLVG---------------------- Mb0857c|M.bovis_AF2122/97 GFAVAPDFIGFGAAYGGAGGLGGAATG-AGGTGGTGGVGAGG-------- Rv0834c|M.tuberculosis_H37Rv GFAVAPDFIGFGAAYGGAGGLGGAATG-AGGTGGTGGVGAGG-------- MMAR_0492|M.marinum_M GSCVAFDFVGFAAAHGGAGGTGGAATG-VGATAGAAGSGGLG-------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 ASGAAGTIIAGNGGNGGAGGAGYAADGPAGPAIGNGGDGGHG-------- Mflv_5091|M.gilvum_PYR-GCK GKGGNGGNGGRGGLFG---------------KGGNAGNGAD--------- Mvan_1264|M.vanbaalenii_PYR-1 GKGGNGGNGGRGSLFG---------------RGGNAGNGGN--------- MSMEG_0868|M.smegmatis_MC2_155 AVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPN TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------LAGNAGLAGN--------- MAV_4827|M.avium_104 -------------------------------------------------- Mb0857c|M.bovis_AF2122/97 -----------FAALGVGVGGAGGAGGAATETGGIGGAGGLG-------- Rv0834c|M.tuberculosis_H37Rv -----------FAALGVGVGGAGGAGGAATETGGIGGAGGLG-------- MMAR_0492|M.marinum_M -----------VAIVGSGVGGVGGVGGAATGAG----------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 -----------GAGGFYGNGGAGGAGGNSAPGGGTGGNGGTGG------- Mflv_5091|M.gilvum_PYR-GCK -------------GGTGGAGGAGGTGG-TGGAGGTGG------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------GGTGGNGGNGGTGG-TGGNGGTGG------------- MSMEG_0868|M.smegmatis_MC2_155 GPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHST TH_3810|M.thermoresistible__bu ----------------TGIGGRGGNGGSSSGTHPMAE------------- MAB_4284c|M.abscessus_ATCC_199 -------------AGLAGNAGLAGNAGLAGNAGLAGN------------- MAV_4827|M.avium_104 ----------------SGLAVVGISAVLALEIALAIG------------- Mb0857c|M.bovis_AF2122/97 -----VGLLGGAGGAGGPGGAASAGSGGHGGTGGDALGLIGAGIGGVGGV Rv0834c|M.tuberculosis_H37Rv -----VGLLGGAGGAGGPGGAASAGSGGHGGTGGDALGLIGAGIGGVGGV MMAR_0492|M.marinum_M ---------------------ATAAAGGAGGLG---LAAVGSGTGGAGGA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 ----DSGAMGSSGGRGGDGGVGTNGGAGGGGGNATSYGTANATGGAGGDG Mflv_5091|M.gilvum_PYR-GCK ----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGG Mvan_1264|M.vanbaalenii_PYR-1 ----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGG MSMEG_0868|M.smegmatis_MC2_155 GQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGG TH_3810|M.thermoresistible__bu ---------------DGEHVKALDGRPGLDGGNGSHGGNGGHGGRGGFLG MAB_4284c|M.abscessus_ATCC_199 --------------AGLAGNAGLAGNAGLAGNAG----LAGNAGLAGNAG MAV_4827|M.avium_104 --------------IRTTGTVALQPTPNQHLIVPTEQAPAPPPVQASAPQ Mb0857c|M.bovis_AF2122/97 GGAATDTGGNGGAGGS--GTGLLGGVGGAGGHGGG-------ASVGTGGS Rv0834c|M.tuberculosis_H37Rv GGAATDTGGNGGAGGS--GTGLLGGVGGAGGHGGG-------ASVGTGGS MMAR_0492|M.marinum_M GGVGAGTGGAGGAGAH--GFGLLSGTAGAGGAGGA-------ASAGTGGA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 GTGSTGNGGSGGDGGN--GGTGHGGGGGPGGTAIN-------YGAGDAFG Mflv_5091|M.gilvum_PYR-GCK KGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGT Mvan_1264|M.vanbaalenii_PYR-1 KGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGT MSMEG_0868|M.smegmatis_MC2_155 RGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGN TH_3810|M.thermoresistible__bu IGGSGGWGGHGGNGGDTDADGGNGGDGGNGGS------------AGRGGT MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAGN-AGLAGNAGLAGNAGLAGN--------AAVAGNA MAV_4827|M.avium_104 PKISVPEPVAAPKPLSPPVAAPLPAAPPPAAPPLP---------EAPPIP Mb0857c|M.bovis_AF2122/97 GGAG----------GDGFGFVGAGGNGGNAGTGVGVNGANGG-------- Rv0834c|M.tuberculosis_H37Rv GGAG----------GDGFGFVGAGGNGGNAGTGVGVNGANGG-------- MMAR_0492|M.marinum_M GGLG----------GTGFGLIAAGGDGGGAGTGVGSNGGDGG-------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 GAAG----------KGGTGVVGGNGGSGGAAYNYGTGNATGA-------- Mflv_5091|M.gilvum_PYR-GCK GGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG-------- Mvan_1264|M.vanbaalenii_PYR-1 GGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG-------- MSMEG_0868|M.smegmatis_MC2_155 GGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATV TH_3810|M.thermoresistible__bu GGLR---------------------------GVFGINGGNGR-------- MAB_4284c|M.abscessus_ATCC_199 AVAG--------------------------NAAVAGNAAVGG-------- MAV_4827|M.avium_104 AAPP----------------------------VVPVPVVVPP-------- Mb0857c|M.bovis_AF2122/97 ----------NGGSATGALAAVG--------------------------- Rv0834c|M.tuberculosis_H37Rv ----------NGGSATGALAAVG--------------------------- MMAR_0492|M.marinum_M ----------GGGGAHAVLAAIA--------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 ----------GGSSGSGGAASVPNSASTA-----------------TATS Mflv_5091|M.gilvum_PYR-GCK ---------TGGTGGQGG-LGGGGGTG----------------------- Mvan_1264|M.vanbaalenii_PYR-1 ---------TGGTGGQGG-LGGVGGTG----------------------- MSMEG_0868|M.smegmatis_MC2_155 IGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATD TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------------------------------------------VL MAV_4827|M.avium_104 -------------------------------------------------- Mb0857c|M.bovis_AF2122/97 GAGAAGGDATSGTGGFGGAGGSARG--LIFALGGAGAAGGDASTGVGGPG Rv0834c|M.tuberculosis_H37Rv GAGAAGGDATSGTGGFGGAGGSARG--LIFALGGAGAAGGDASTGVGGPG MMAR_0492|M.marinum_M GSGGQGQAGTSGFGGFGGSGGSAES--LFFSIGGAGGAGGDASTGGGGLG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 GSGGAGGDGTDGGNGGSGGFAFTFG--TGNIIAGVGGGGGTGSTGVGGIG Mflv_5091|M.gilvum_PYR-GCK GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFG Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFG MSMEG_0868|M.smegmatis_MC2_155 GHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNG TH_3810|M.thermoresistible__bu --AGLGGRGXXXXGGGVG---------------AAVRSGNGVFSGGGGTP MAB_4284c|M.abscessus_ATCC_199 NTGVSGAIGGSSHVGGAINESLGGS----GSVGGSTAVGGGAHTGVGGGV MAV_4827|M.avium_104 --VPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVG Mb0857c|M.bovis_AF2122/97 GPGGTGTASSPFGIAIAIGGAGAQGGAGTSG-ATGGAGGDGVFEGIAVLG Rv0834c|M.tuberculosis_H37Rv GPGGTGTASSPFGIAIAIGGAGAQGGAGTSG-ATGGAGGDGVFEGIAVLG MMAR_0492|M.marinum_M GNGGVAVAHSPIGIDIGIGGAGGHGGSGTSG-ADGGAGGVSISEGIFAID MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 GSGGGADINNGAFTVVPQGGAGGHGGDGATDGGAGGAGGFTEIDSSASVI Mflv_5091|M.gilvum_PYR-GCK GSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAG Mvan_1264|M.vanbaalenii_PYR-1 GVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAG MSMEG_0868|M.smegmatis_MC2_155 GDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGS TH_3810|M.thermoresistible__bu SAGFGVPTTIQFPAGSCTSRAVSREGIMPSSRAASARAGAACASSTSRSR MAB_4284c|M.abscessus_ATCC_199 STGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGS MAV_4827|M.avium_104 GTVPQSPPQHQTPPGEGTPPKPDGPGNYGGGHVPTPGAGGSGGSGGGHVP Mb0857c|M.bovis_AF2122/97 LGFGGAAGAGG-AATGDGATGGAGGFGGAG-AGIANFLGFSVLHGGAGGA Rv0834c|M.tuberculosis_H37Rv LGFGGAAGAGG-AATGDGATGGAGGFGGAG-AGIANFLGFSVLHGGAGGA MMAR_0492|M.marinum_M VNLGGAGGDGGTATTGTAGSGGNGGFVEN-----FDFFGFGVAHGGDGGS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 AATGGAGGDGGSGGTGRGGTGG-GGTGGGG-TGGGGGVGINNGSGEAIGG Mflv_5091|M.gilvum_PYR-GCK KAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGA Mvan_1264|M.vanbaalenii_PYR-1 TAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGS MSMEG_0868|M.smegmatis_MC2_155 TLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGD TH_3810|M.thermoresistible__bu RSFCCSRA------------------------------------------ MAB_4284c|M.abscessus_ATCC_199 HVGGGISESLGGSGSVGGSTAVGGGAHTG--VGGGVNTGVGVGSHVGGGI MAV_4827|M.avium_104 TPGAGGSGGSGGGHVPTPGTGGPGGTGGSG--------GGHVPTPGAGTP Mb0857c|M.bovis_AF2122/97 GGTATGTGGNGGAGGGGGLSSPVILGIGIG-------------------- Rv0834c|M.tuberculosis_H37Rv GGTATGTGGNGGAGGGGGLSSPVILGIGIGGAGGDGGGALGVLGGMGGDG MMAR_0492|M.marinum_M GGAASGAGGIGGAGGNGGSGTTPLFGAYSGGAGGDGGAATG-TGGAGGNG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 APGAGGTGAVGGDGGQGGAAYSYGTGDATGSAGAAGTAGTTGVGGTGGAG Mflv_5091|M.gilvum_PYR-GCK TGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAG Mvan_1264|M.vanbaalenii_PYR-1 AGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAG MSMEG_0868|M.smegmatis_MC2_155 GGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 SESLGGSGSVGGSTAVGG-------------------------------- MAV_4827|M.avium_104 GGSGGGHLPFPGAG------------------------------------ Mb0857c|M.bovis_AF2122/97 ----------------------------GAGGNGGDALGLVGVGGNGGNA Rv0834c|M.tuberculosis_H37Rv GDGGEAVAVGIAVGGAGGAGGAAPTGNGGAGGNGGDALGLVGVGGNGGNA MMAR_0492|M.marinum_M GAGGAASGLGVGIGGAGGHGGAAPTGNGGSGGAGAGGLGLIGAGGNGGDA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 GAAYTLN------------GASTATATGGIGGNGGDGGTANGSNGGNGGA Mflv_5091|M.gilvum_PYR-GCK KAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG----- Mvan_1264|M.vanbaalenii_PYR-1 KAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG----- MSMEG_0868|M.smegmatis_MC2_155 WVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVW TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------GAHTSAINDALGGSGSVGGSTAVGGGAHTSA MAV_4827|M.avium_104 ------------------------STPGGSGGGHLPTPGAGTPGG----- Mb0857c|M.bovis_AF2122/97 G-----TGFGANTGGNGGDTTIVVN----GMLAPSTLGYGGNG---VNGG Rv0834c|M.tuberculosis_H37Rv G-----TGFGANTGGNGGDTTIVVN----GMLAPSTLGYGGNGGNGVNGG MMAR_0492|M.marinum_M G-----AGVAAADGGDGGNAGLVIN----GTYEASPYGNGGNGGNGVNGG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 GGYASTTGTGTASVGNGGRGGDGTA----TVATGGTGGVGGNAHAPAGSP Mflv_5091|M.gilvum_PYR-GCK ------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGA Mvan_1264|M.vanbaalenii_PYR-1 ------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGA MSMEG_0868|M.smegmatis_MC2_155 KSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGS TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 IN-------ESMNSSINASHSSSMN-----ESFGSSMGSHGAAGTGFEAQ MAV_4827|M.avium_104 -----------GLGGFGGGHAPAPG--------GGLGGGGGHAPAPGGGL Mb0857c|M.bovis_AF2122/97 A-GGTGGKAG--VFG-APGQNGLP----- Rv0834c|M.tuberculosis_H37Rv A-GGTGGKAG--VFG-APGQNGLP----- MMAR_0492|M.marinum_M S-GGKGGSAG--QVGGTPGQNGSP----- MLBr_01183|M.leprae_Br4923 ----------------------------- MUL_0572|M.ulcerans_Agy99 V-PGVGGKGGNPGPGGKPGPNGADGIVV- Mflv_5091|M.gilvum_PYR-GCK G--GAGGSGGSGGSGGSGGSGGAAGDSDD Mvan_1264|M.vanbaalenii_PYR-1 G--GAGGSGGSGGSGGAGGSGGAAGDSD- MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGNGGNGGADGTPGTAGTTGANNP TH_3810|M.thermoresistible__bu ----------------------------- MAB_4284c|M.abscessus_ATCC_199 G--HAQGHASETAHTTLPGAEHH------ MAV_4827|M.avium_104 G--GFGGGHSGGGLGGLGGGHK-------