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VPRPLKLYRAAIETAAFADGIGVDNISVMEHHGSEDGYLPQPFTMAGGMAAVTKHARLLIGAVVLPLHDP VLVAEQIAIADLMSGGRINVTFGAGYVASEFAMFGKSLADRAKLMDSGIETIIRALRGETFEADGRPVCV RPLPIQKPEEIILVGGGVKASARRAARFGLGFLPMVPDLVDVYLEECRKHGREPGLYFRPMLIPISIHLC EDPERGWAAIERHAIHVITEYAKWAEQEGDASNSPFKSLTDPAVLRQAGLFAAWTPDDLLARVPDVVDRS GFAFQPLLGGLSPEEGWKSLKQLEQTMPKLKAAIAALD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1265 | - | - | 100% (318) | hypothetical protein MUL_1265 |
| M. ulcerans Agy99 | MUL_4877 | - | 7e-45 | 35.83% (307) | hypothetical protein MUL_4877 |
| M. ulcerans Agy99 | MUL_1043 | - | 3e-18 | 33.72% (172) | hypothetical protein MUL_1043 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3106c | - | 2e-13 | 31.91% (141) | hypothetical protein Mb3106c |
| M. gilvum PYR-GCK | Mflv_1590 | - | 4e-19 | 34.50% (171) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3079c | - | 2e-13 | 31.91% (141) | hypothetical protein Rv3079c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0366 | - | 6e-16 | 31.41% (191) | hypothetical protein MAB_0366 |
| M. marinum M | MMAR_3375 | - | 1e-178 | 98.72% (313) | hypothetical protein MMAR_3375 |
| M. avium 104 | MAV_2133 | - | 2e-47 | 35.37% (311) | hypothetical protein MAV_2133 |
| M. smegmatis MC2 155 | MSMEG_0654 | - | 5e-18 | 33.93% (168) | hypothetical protein MSMEG_0654 |
| M. thermoresistible (build 8) | TH_3375 | - | 2e-26 | 28.57% (322) | PUTATIVE putative conserved hypothetical protein |
| M. vanbaalenii PYR-1 | Mvan_5167 | - | 3e-18 | 35.67% (171) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1590|M.gilvum_PYR-GCK -----MQLVFPLPHMLRLPAMSQP-WEGSVTGADQTRMAKCADAWGYDMI
Mvan_5167|M.vanbaalenii_PYR-1 -----MRLVFALPHMLRLPAMSQP-WEASVTGADQTRMARCADQWGYDMI
MSMEG_0654|M.smegmatis_MC2_155 MKEFGMKLVFNLPHMLRLKAMMQP-WEAEVTGADQTRMVKCADRWGYDMI
Mb3106c|M.bovis_AF2122/97 -------MQFGVLTFVTDEGIGP----AELGAALEHRGFESLFLAEHTHI
Rv3079c|M.tuberculosis_H37Rv -------MQFGVLTFVTDEGIGP----AELGAALEHRGFESLFLAEHTHI
MUL_1265|M.ulcerans_Agy99 ---------------MPRP-------LKLYRAAIET--AAFADGIGVDNI
MMAR_3375|M.marinum_M ----MRTIETTVSFDMRAPEWGAP-TAELYRAAIEM--AAFADGIGVDNI
MAV_2133|M.avium_104 --------MYTLRFDMRDPEWAAP-PADLYAAAPEM--AAWAEEHGGLAA
MAB_0366|M.abscessus_ATCC_1997 -------MKIGVVAPVELGVTAEPDKILEFARAAERLGFSEISVVEHAVV
TH_3375|M.thermoresistible__bu -------VGLGALTAQTRSGTAAE---STEALTMLLDTCVLAEDEGLDSA
:
Mflv_1590|M.gilvum_PYR-GCK AVPEHFVIP----AEHVELSGPHYLQSTVAQAYLAGATERIRLNSCITVL
Mvan_5167|M.vanbaalenii_PYR-1 AVPEHFVIP----AEHVELSGPHYLQSTVAQAYLAGATERIRLNSCITVL
MSMEG_0654|M.smegmatis_MC2_155 AVPEHFVIP----NEHVELSGPHYLQSTVAQAYIAGATERIMLNSCITVL
Mb3106c|M.bovis_AF2122/97 PVNTQSPYPG---GGPIPEKYYRTLDPFVALAAAAATTQSLVLGTGIALI
Rv3079c|M.tuberculosis_H37Rv PVNTQSPYPG---GGPIPEKYYRTLDPFVALAAAAATTQSLVLGTGIALI
MUL_1265|M.ulcerans_Agy99 SVMEHHGSE-----------DGYLPQPFTMAGGMAAVTKHARLLIGAVVL
MMAR_3375|M.marinum_M SVMEHHGSE-----------DGYLPQPFTMAGGMAAVTKHARLLIGAVVL
MAV_2133|M.avium_104 VLCEHHGSE-----------DGYLPSPFLLASAVAARTQRLALSL-ILIL
MAB_0366|M.abscessus_ATCC_1997 IGDTQSTYPYSPTGQSHLPDDIDIPDPLELLSFVAAATTTLGLSTGVLVL
TH_3375|M.thermoresistible__bu WVAEHHFAA-----------DGFLSSPMTVLAALSQRTSRIRLSTNVMIG
: .. . : * * :
Mflv_1590|M.gilvum_PYR-GCK PLQHPIVLAKALATADWMSGGRMMVTFGVGWLKGEFDALGVPFRERGRIA
Mvan_5167|M.vanbaalenii_PYR-1 PLQHPVVLAKALATADWMSGGRMMVTFGVGWLQGEFEALGVPFRERGRMA
MSMEG_0654|M.smegmatis_MC2_155 PLQHPIVLAKALATADWMSSGRMMVTFGVGWLQREFELLGVPFHERGRMA
Mb3106c|M.bovis_AF2122/97 PERDPIVTAKEVASLDLVSQGRFRFGVGVGWLREEVANHGVDPAVRGRVI
Rv3079c|M.tuberculosis_H37Rv PERDPIVTAKEVASLDLVSQGRFRFGVGVGWLREEVANHGVDPAVRGRVI
MUL_1265|M.ulcerans_Agy99 PLHDPVLVAEQIAIADLMSGGRINVTFGAGYVASEFAMFGKSLADRAKLM
MMAR_3375|M.marinum_M PLHDPVLVAEQIAIADLMSGGRINVTFGAGYVASEFAMFGKSLADRAKLM
MAV_2133|M.avium_104 PFYEPVRLAEDMAVLDIISNGRASYILALGYRPEEFEHFGVPIKKRGRLC
MAB_0366|M.abscessus_ATCC_1997 PDHHPVVLAKRLATLDRLSRGRLRICAGVGWMREEIEACGGDFDRRGRAA
TH_3375|M.thermoresistible__bu PLYDPIRLAEDAAVVDQLSRGRLMLGLGLGYRDVEFAGLGRRRQERGRRL
* .*: *: * * :* ** . *: *. * *.:
Mflv_1590|M.gilvum_PYR-GCK DEYLAAIVELWTSD-SPSFDGRYVSFDEIAFEPKPVQRPHLPIWIGGDAD
Mvan_5167|M.vanbaalenii_PYR-1 DEYLAVIKELWTSD-APSFEGKYVSFREVAFEPKPVQKPHLPIWIGGDAD
MSMEG_0654|M.smegmatis_MC2_155 DEYLAAIVELWTSD-SPKFEGRYVSFGDIAFEPKPVQKPHLPIFIGGDAD
Mb3106c|M.bovis_AF2122/97 DERLRAIIEIWTQE-QAEFHGTYVDFDPIYCWPKPVTKPYPPLYVGGGP-
Rv3079c|M.tuberculosis_H37Rv DERLRAIIEIWTQE-QAEFHGTYVDFDPIYCWPKPVTKPYPPLYVGGGP-
MUL_1265|M.ulcerans_Agy99 DSGIETIIRALRGE-TFEADGR-----PVCVRPLPIQKPEEIILVGGGVK
MMAR_3375|M.marinum_M DSGIETIIRALRGE-TFEADGR-----PVCVRPLPIQKPEEIILVGGGVK
MAV_2133|M.avium_104 DEKLALLRRLLAGE-TVVEDGR-----RITVTPRPLTPGGPGLMWGGGTI
MAB_0366|M.abscessus_ATCC_1997 DEAIAVMRALWSTDGPTSHDGEFYSFRNAYSYPKPVRPQGVPLYIGGHSK
TH_3375|M.thermoresistible__bu DDLINVLRQAWSGK-PVEHHGLG-TYKTPPVTPLPFQQDGPPVLVGAFAE
*. : : . .* * *. : *.
Mflv_1590|M.gilvum_PYR-GCK AALRRAAKYASGWWSFLTPPDK-IAERVEFIKSQD---------------
Mvan_5167|M.vanbaalenii_PYR-1 AALRRAAKYASGWWSFLTPPEK-LAERLDFIKSQP---------------
MSMEG_0654|M.smegmatis_MC2_155 AALRRAARYASGWWSFLTPPEK-LAERIDFIKSQP---------------
Mb3106c|M.bovis_AF2122/97 ANFPRIARLNAGWIAISPSPQR-LSGPLQRLRAMA---------------
Rv3079c|M.tuberculosis_H37Rv ANFPRIARLNAGWIAISPSPQR-LSGPLQRLRAMA---------------
MUL_1265|M.ulcerans_Agy99 ASARRAARFGLGFLP--MVPDL-VDVYLEECRKHGREPG-LYFRPMLIPI
MMAR_3375|M.marinum_M ASARRAARFGLGFLP--MVPDL-VDVYLEECRKHGREPG-LYFRPMLIPI
MAV_2133|M.avium_104 AAARRAGRYGLGMLGNANAPGI-QEAYEEACREHGHPPGPTMFPDRNTPS
MAB_0366|M.abscessus_ATCC_1997 AAARRAGRLGSGFQPLGLVGDD-LTAAVGVMRAAAVDAG-----------
TH_3375|M.thermoresistible__bu AGLRRAVRLGNGWLAPELRHWRGLEKRVAALGLDSRTDP------FHVAV
* * : *
Mflv_1590|M.gilvum_PYR-GCK ----GYDGRPFDVVHGLGTNRVGEGHVAQKDPHARPGMSAAEIAD-KLNW
Mvan_5167|M.vanbaalenii_PYR-1 ----DYDGRPFDVVHGLGTNRVGEGHVAQHDPDARPGMSAAEIVD-RLSW
MSMEG_0654|M.smegmatis_MC2_155 ----EYDGRAFDVVHGMATTRVGEGHTVRDDPNARPGMSAQEIID-RLSW
Mb3106c|M.bovis_AF2122/97 ----GGDVP---------------------VTVCQWGEAAAKDLE-GYRH
Rv3079c|M.tuberculosis_H37Rv ----GGDVP---------------------VTVCQWGEAAAKDLE-GYRH
MUL_1265|M.ulcerans_Agy99 SIHLCEDPERGWAAIERHAIHVITEYAKWAEQEGDASNSPFKSLT-DPAV
MMAR_3375|M.marinum_M SIHLCEDPERGWAAIERHAIHVITEYAKWAEQEGDASNSPFKSLT-DPAV
MAV_2133|M.avium_104 VVFVAEDVDQAWKEIGEHLLHDVRTYAAWNP--GDETTAGFSHVN-TIDE
MAB_0366|M.abscessus_ATCC_1997 -----RDPRGLDLVLG-----------------HGLHRVDQAALD-QAAH
TH_3375|M.thermoresistible__bu TVNAFVAARDAWETVRPGVAHVAGQYRSWLVESGDLPALEGKEFEYEADE
Mflv_1590|M.gilvum_PYR-GCK LGEQGVTVSAVPIPKVSGVEEYLDYAQWVIEEIRPQVR------------
Mvan_5167|M.vanbaalenii_PYR-1 LGAQGVTVSAVPIPKVRGVEEYLDYAQWVIEEIKPQVP------------
MSMEG_0654|M.smegmatis_MC2_155 LGEQGVTVSAVPLPPVRGVDEYLDYAQWVIEEIKPQVP------------
Mb3106c|M.bovis_AF2122/97 LGVERVLLELPTEPRDP-TLRYLDKLQAELARLA----------------
Rv3079c|M.tuberculosis_H37Rv LGVERVLLELPTEPRDP-TLRYLDKLQAELARLA----------------
MUL_1265|M.ulcerans_Agy99 LRQAGLFAAWTPDDLLARVPDVVDRSGFAFQPLLGGLSPEEGWK------
MMAR_3375|M.marinum_M LRQAGLFAAWTPDDLLARVPDMVDRSGFAFQPLLGGLSPEEGWK------
MAV_2133|M.avium_104 LRETG--TSHVIISVPEAISRVKAGQVLNLSPLCGGLPPDIAWP------
MAB_0366|M.abscessus_ATCC_1997 AGAGRMLLSASR--RATTLEAVLEEMAGCATRLELGGPR-----------
TH_3375|M.thermoresistible__bu TGKPPQFVAGTPEQCVAQLRPWWRILARLPEHVQPHLILGMTFPGVSREA
:
Mflv_1590|M.gilvum_PYR-GCK --------------------
Mvan_5167|M.vanbaalenii_PYR-1 --------------------
MSMEG_0654|M.smegmatis_MC2_155 --------------------
Mb3106c|M.bovis_AF2122/97 --------------------
Rv3079c|M.tuberculosis_H37Rv --------------------
MUL_1265|M.ulcerans_Agy99 SLKQLEQTMPKLKAAIAALD
MMAR_3375|M.marinum_M SLKLLEQTMPKLKAAIAALD
MAV_2133|M.avium_104 YLKRVGEVV--LPEALGH--
MAB_0366|M.abscessus_ATCC_1997 --------------------
TH_3375|M.thermoresistible__bu TFESVRLLAREVVPALNAEE