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KFVDNAQVAVLAAAKDMLRRGLVEGTAGNISARCADGNLVITPSSVDYADMTLDDLVQVDADGTVLHAKA GRAPSTEMHLHLACYQAFDDIGSVIHSHPVWATMFAIAHQPIPACIDEFAVYCGGDVRCAEYAASGTPEV GRNAVAALQGRAAALIANHGLVAVGPRPDKVLHVTALVERTAQIVWGARALGGPVPIPEDVNRNFAGVYA YLRANPM*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0822 | fucA | - | 100% (218) | L-fuculose-phosphate aldolase |
| M. ulcerans Agy99 | MUL_3144 | araD | 2e-10 | 23.08% (195) | ribulose-5-phosphate 4-epimerase, AraD |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0748c | fucA | 1e-107 | 85.32% (218) | L-fuculose-phosphate aldolase |
| M. gilvum PYR-GCK | Mflv_0622 | - | 7e-08 | 23.22% (211) | class II aldolase/adducin family protein |
| M. tuberculosis H37Rv | Rv0727c | fucA | 1e-107 | 85.32% (218) | L-fuculose-phosphate aldolase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2912c | - | 1e-12 | 29.73% (185) | aldolase |
| M. marinum M | MMAR_1064 | fucA | 1e-125 | 100.00% (218) | L-fuculose-1-phosphate aldolase FucA |
| M. avium 104 | MAV_4439 | - | 1e-105 | 84.79% (217) | L-fuculose-phosphate aldolase |
| M. smegmatis MC2 155 | MSMEG_1714 | - | 2e-23 | 35.57% (194) | L-ribulose-5-phosphate 4-epimerase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0451 | - | 2e-12 | 27.87% (183) | hypothetical protein Mvan_0451 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0748c|M.bovis_AF2122/97 ---------------------------------MNFVDDPESAVLAAAKD
Rv0727c|M.tuberculosis_H37Rv ---------------------------------MNFVDAPESAVLAAAKD
MUL_0822|M.ulcerans_Agy99 ---------------------------------MKFVDNAQVAVLAAAKD
MMAR_1064|M.marinum_M ---------------------------------MKFVDNAQVAVLAAAKD
MAV_4439|M.avium_104 ---------------------------------MKFVDDPEQAVLDAAKD
MSMEG_1714|M.smegmatis_MC2_155 --------------------------MSVTTEIDAVIRQLRKQVCDLHAE
MAB_2912c|M.abscessus_ATCC_199 MTSGNVVAGEELSAYMVGSADGVQLGPAAAETVTQERERRLRELAAAFRI
Mvan_0451|M.vanbaalenii_PYR-1 MTS---TMHDSKSDLMRRALDGLSR------NVTESSLTLREKLAVTCRA
Mflv_0622|M.gilvum_PYR-GCK ---------------------------MSSTPSGAGLDTERHAIALACRV
:
Mb0748c|M.bovis_AF2122/97 MLRRGLVEGTAGNISARRSDGN-VVIT--PSSVDYAEMLLHDLVLVDAGG
Rv0727c|M.tuberculosis_H37Rv MLRRGLVEGTAGNISARRSDGN-VVIT--PSSVDYAEMLLHDLVLVDAGG
MUL_0822|M.ulcerans_Agy99 MLRRGLVEGTAGNISARCADGN-LVIT--PSSVDYADMTLDDLVQVDADG
MMAR_1064|M.marinum_M MLRRGLVEGTAGNISARCADGN-LVIT--PSSVDYADMTLDDLVQVDADG
MAV_4439|M.avium_104 MLRRGLVEGTAGNISARRSDGN-IVIT--PSSVDYRDMQLDDLVLIDPAG
MSMEG_1714|M.smegmatis_MC2_155 LTRYQLVIWTAGNVSARVPDRD-LMIIK-PSGVDYDSMTPEQMVVCDLHG
MAB_2912c|M.abscessus_ATCC_199 FGTFGFSEGVAGHITVRDPEFPDTFWVN-PFGMNFRHITVSDLIQVDHDG
Mvan_0451|M.vanbaalenii_PYR-1 LFDAGHDSGLAGQITAR-AEAPGTYYTQ-RLGLGFDEITAGNLLLVDEDL
Mflv_0622|M.gilvum_PYR-GCK LAARDLAPGILGHISLRVDRDRLLIRCRGPRERGLAFTSAEDIRMVTLDG
: *::: * . ::
Mb0748c|M.bovis_AF2122/97 AVLHAK---DGRSPSTELNLHLACYRAFDDIGSVIHSHPVWATMFAVAHE
Rv0727c|M.tuberculosis_H37Rv AVLHAK---DGRSPSTELNLHLACYRAFDDIGSVIHSHPVWATMFAVAHE
MUL_0822|M.ulcerans_Agy99 TVLHAK---AGRAPSTEMHLHLACYQAFDDIGSVIHSHPVWATMFAIAHQ
MMAR_1064|M.marinum_M TVLHAK---AGRAPSTEMHLHLACYQAFDDIGSVIHSHPVWATMFAIAHQ
MAV_4439|M.avium_104 SVLQAA---QGRSPSTEMQLHLACFAAFDDIGCVIHSHPVWATMFAIAHQ
MSMEG_1714|M.smegmatis_MC2_155 ELVDG-----DLAPSSDTAAHAYVYRHMPEVGGVVHTHSTYATAWAARGE
MAB_2912c|M.abscessus_ATCC_199 NVITG----SRPVNRAAFCIHSEVHKARPDVIAAAHAHSVHGKAFSSLGQ
Mvan_0451|M.vanbaalenii_PYR-1 KVLDG----EGMAN-PANRFHSWIYRARPDVNCIVHTHPFHVAALSMLEV
Mflv_0622|M.gilvum_PYR-GCK TAGGKGELDDGYQPPNELPLHTEVLRTRRDVNAVVHAHPEAVVAADLAGL
* :: *:*.
Mb0748c|M.bovis_AF2122/97 PIPACIDEFAI----YCGGDVRCTEY-AASGTPEVGRNAVRALEGRA--A
Rv0727c|M.tuberculosis_H37Rv PIPACIDEFAI----YCGGDVRCTEY-AASGTPEVGRNAVRALEGRA--A
MUL_0822|M.ulcerans_Agy99 PIPACIDEFAV----YCGGDVRCAEY-AASGTPEVGRNAVAALQGRA--A
MMAR_1064|M.marinum_M PIPACIDEFAV----YCGGDVRCAEY-AASGTPEVGRNAVAALQGRA--A
MAV_4439|M.avium_104 SIPACIDEFAV----YCGGDVRCAEY-AASGSPDVGANAVKALQGRG--A
MSMEG_1714|M.smegmatis_MC2_155 AIPCVLTMIAD----EFGGDIPVGPF-ALIGDDSIGRGIVETLQHSNSRA
MAB_2912c|M.abscessus_ATCC_199 PLLPITQDACA----FYQDHAVYTDYRGVVGDLEEGRAIGSALGPAK--A
Mvan_0451|M.vanbaalenii_PYR-1 PLVVSQMDIAP----LYGDCAFLPDWPGVPVGNEEGEIISAALGDKK--A
Mflv_0622|M.gilvum_PYR-GCK AVRPIVGAFDIPGFRLAAAGVPVYRRGVLVRNRQLAQEMVAAMADRP--V
.: . . :: .
Mb0748c|M.bovis_AF2122/97 ALIANHGLVAVGPRPDQVLRVTALVERTAQIVWGARALG-GPVPIPEDVC
Rv0727c|M.tuberculosis_H37Rv ALIANHGLVAVGPRPDQVLRVTALVERTAQIVWGARALG-GPVPIPEDVC
MUL_0822|M.ulcerans_Agy99 ALIANHGLVAVGPRPDKVLHVTALVERTAQIVWGARALG-GPVPIPEDVN
MMAR_1064|M.marinum_M ALIANHGLVAVGPRPDKVLHVTALVERTAQIVWGARALG-GPVPIPEDVN
MAV_4439|M.avium_104 ALIANHGLVAVGPRPDKVLHITALVERTAQIVWGARALG-GPVPIPEDVN
MSMEG_1714|M.smegmatis_MC2_155 VLMRNHGPFTVGRDARDAVKAAVMVEDVARTVHISRQLG-TPDVIPPADV
MAB_2912c|M.abscessus_ATCC_199 VILQNHGLLTVGHSVAEAAWWFITMERSCQAQLLAMAAG-EPRTIDHDTA
Mvan_0451|M.vanbaalenii_PYR-1 ILLAHHGHVVAGASVEEACSLAMLVERGAKLQLAAMAAG-TIAPLPDRLA
Mflv_0622|M.gilvum_PYR-GCK VVLRAHGLTSAADTVERAVLQAISVDTISRLSLQIASAGGTLADLPDADA
:: ** .. . :: .: * :
Mb0748c|M.bovis_AF2122/97 RNFTGVYGY------------------LRANPL-----
Rv0727c|M.tuberculosis_H37Rv RNFTGVYGY------------------LRANPL-----
MUL_0822|M.ulcerans_Agy99 RNFAGVYAY------------------LRANPM-----
MMAR_1064|M.marinum_M RNFAGVYAY------------------LRANPM-----
MAV_4439|M.avium_104 RNFAAVYGY------------------LRANP------
MSMEG_1714|M.smegmatis_MC2_155 RRLFDRYQN------------------VYGQPQASQEG
MAB_2912c|M.abscessus_ATCC_199 VSVYNQIGTP---VAGWFQFQPLWDDVIRTAPEALH--
Mvan_0451|M.vanbaalenii_PYR-1 REAHDWTLTP---KRSQANFAYYARRALANHPDALDR-
Mflv_0622|M.gilvum_PYR-GCK AELPDLGNAFNETIAWRHELARLETHGLSCHPSEKRSS
: *