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SNGKPNILVIWGDDIGITNLSCYSDGLMGYRTPHIDRIANEGMRFTDAYGEQSCTAGRAAFISGQSVYRT GMSKVGMPDSDIGWSGQDPTIADLLKPLGYATGQFGKNHLGDRNKHLPTVHGFDEFFGNLCHLNAEEEPE LPDYPKSDRFPVLAELNRPRGVLRCWATEEVSDEPDDPKYGPVGKQRIVDTGPLTKQRMETIDDETTEAC VDFIKRQAAADTPFFVWMNMTHMHLRTHTKPESVGQAGVWQSPYHDTMIDHDRNVGQLLDALDELGIAQD TIVIYSTDNGPHANTWPDGATTPFRSEKNTNWEGALRIPEMIRWPGKISAGVVSNEIIQHHDRLPTFLAA AGEPDIIEKLKKGHKISVRGDDKEFKVHLDAFNLLPYLTGEVEESPRQGFIYFSDDCDVLGIRFHNWKIV FQEQRCQGTLQVWAEPFIPLRVPKIFNLRTDPYERADITSNTYYDWFLDHDFIAFYGTAICTQFLETFKE FPPRHPPARFTIDQAVEKLQAIVKD*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_0227 | aslA | - | 100% (516) | arylsulfatase, AslA |
M. ulcerans Agy99 | MUL_2658 | atsB | 1e-11 | 31.39% (137) | arylsulfatase AtsB (aryl-sulfate sulphohydrolase) |
M. ulcerans Agy99 | MUL_0454 | atsD | 2e-09 | 23.29% (438) | arylsulfatase AtsD |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3327c | atsB | 8e-10 | 29.93% (137) | arylsulfatase AtsB |
M. gilvum PYR-GCK | Mflv_5039 | - | 2e-09 | 27.63% (152) | sulfatase |
M. tuberculosis H37Rv | Rv0711 | atsA | 2e-10 | 28.29% (152) | arylsulfatase AtsA |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_4469c | - | 9e-10 | 25.44% (338) | sulfatase family protein |
M. marinum M | MMAR_4410 | aslA | 0.0 | 98.45% (516) | arylsulfatase, AslA |
M. avium 104 | MAV_2989 | - | 2e-17 | 24.36% (427) | arylsulfatase |
M. smegmatis MC2 155 | MSMEG_1228 | - | 2e-42 | 29.09% (471) | sulfatase |
M. thermoresistible (build 8) | TH_0315 | - | 1e-10 | 22.93% (314) | arylsulfatase |
M. vanbaalenii PYR-1 | Mvan_4629 | - | 0.0 | 63.09% (512) | sulfatase |
CLUSTAL 2.0.9 multiple sequence alignment MUL_0227|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4410|M.marinum_M -------------------------------------------------- Mvan_4629|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_5039|M.gilvum_PYR-GCK -------------------------------------------------- Rv0711|M.tuberculosis_H37Rv -------------------------------------------------- TH_0315|M.thermoresistible__bu -------------------------------------------------- Mb3327c|M.bovis_AF2122/97 MMSEDNALVLVAGYQDLDSARHDFQTLVDAAKDKSIPLQGAVLIGKDAEG MAV_2989|M.avium_104 -------------------------------------------------- MSMEG_1228|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4469c|M.abscessus_ATCC_199 -------------------------------------------------- MUL_0227|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4410|M.marinum_M -------------------------------------------------- Mvan_4629|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_5039|M.gilvum_PYR-GCK -------------------------------------------------- Rv0711|M.tuberculosis_H37Rv -------------------------------------------------- TH_0315|M.thermoresistible__bu -------------------------------------------------- Mb3327c|M.bovis_AF2122/97 SPVLVDTGNRLGRRGAAWGAGVGLAIGLFSPALLASAALGAATGALAGTF MAV_2989|M.avium_104 -------------------------------------------------- MSMEG_1228|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4469c|M.abscessus_ATCC_199 -------------------------------------------------- MUL_0227|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4410|M.marinum_M -------------------------------------------------- Mvan_4629|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_5039|M.gilvum_PYR-GCK -------------------------------------------------- Rv0711|M.tuberculosis_H37Rv -------------------------------------------------- TH_0315|M.thermoresistible__bu -------------------------------------------------- Mb3327c|M.bovis_AF2122/97 AHHRIKTGLADKIGQALAAGRAVVIAVTEAQGRLEAGQALASSPMKSVAE MAV_2989|M.avium_104 -------------------------------------------------- MSMEG_1228|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4469c|M.abscessus_ATCC_199 -------------------------------------------------- MUL_0227|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4410|M.marinum_M -------------------------------------------------- Mvan_4629|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_5039|M.gilvum_PYR-GCK -----------------------------MTTEFNGKIALDIRDSEPDWG Rv0711|M.tuberculosis_H37Rv -------------------------MAPEATEAFNGTIELDIRDSEPDWG TH_0315|M.thermoresistible__bu ------------------------------MADFGGKIELDIRDSEPDWG Mb3327c|M.bovis_AF2122/97 LSRSTLRSLGAALREAMGKFNPDRTRLPLPQRRFGGVVGRTMAESVGDWS MAV_2989|M.avium_104 -------------------------------------------------- MSMEG_1228|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4469c|M.abscessus_ATCC_199 ----------------MAELNRRTVLTTGAIAAGAAAVGFGGYELLGTPR MUL_0227|M.ulcerans_Agy99 ------MSNGKPNILVIWGDDIGITNLSCYSDGLM-GYRTPHIDRIANEG MMAR_4410|M.marinum_M ------MPNGKPNILVIWGDDIGITNLSCYSDGLM-GYRTPHIDRIANEG Mvan_4629|M.vanbaalenii_PYR-1 ------MGD-KPNILIIWGDDIGQSNLSCYSDGLM-GYRTANIDRIAAEG Mflv_5039|M.gilvum_PYR-GCK PFAAPTAQPEAPNVLYLVWDDIGIATWDCFGG----LVDMPAMSRIAERG Rv0711|M.tuberculosis_H37Rv PYAAPVAPEHSPNILYLVWDDVGIATWDCFGG----LVEMPAMTRVAERG TH_0315|M.thermoresistible__bu PFAAPTAPEGAPNILYVVWDDVGIGTWDCFGG----LVEMPTMSRIAEQG Mb3327c|M.bovis_AF2122/97 IVPSPFPPDDAPNVLIVLIDDAGFGGPDTFGG----AIRTPTLSRLAQNG MAV_2989|M.avium_104 --------MKRPNFLVIVADDLGFSDLGAFGG----EIETPNLDRLAYAG MSMEG_1228|M.smegmatis_MC2_155 -------MPEKPNIVYFHVDNLGMGELGCYGGGILRGADTVRMDAFAAES MAB_4469c|M.abscessus_ATCC_199 RNSSSGSDGNKPNILVIVVDQMR--APQWFPDVQKLTNILPNLSRLHRDS **.: . *: : . : . . MUL_0227|M.ulcerans_Agy99 MRFTDAYGEQ-SCTAGRAAFISGQSVYRTGMSKVG---------MPDSDI MMAR_4410|M.marinum_M MRFTDAYGEQ-SCTAGRAAFISGQSVYRTGMSKVG---------MPGSDI Mvan_4629|M.vanbaalenii_PYR-1 ARFTDYYGEQ-SCTAGRAAFITGQNPYRTGLTKVG---------MPGAPI Mflv_5039|M.gilvum_PYR-GCK VRLSQFHTTA-LCSPTRASLLTGRNATTVGMATIEEFTD----GFPNCNG Rv0711|M.tuberculosis_H37Rv VRLSQFHTTA-LCSPTRASLLTGRNATTVGMATIEEFTD----GFPNCNG TH_0315|M.thermoresistible__bu VRLSQFHTTA-LCSPTRAALLTGRNPTTVGMATIEEFTD----GFPNCSG Mb3327c|M.bovis_AF2122/97 LIYNRFHVTA-VCSPTRAALLTGRNHHRVGFGSVCEFPG----PYPGYSA MAV_2989|M.avium_104 IRLTDFHSAP-ACSPTRAMLLTGTDHHIAGIGTMLEVAAPQFHGAPGYEG MSMEG_1228|M.smegmatis_MC2_155 LKLTHFVVEP-QCTPTRSALMTGRYPIRSGNHTIA---------LGGNGG MAB_4469c|M.abscessus_ATCC_199 VSFASHYTASNMCTPSRGAMTTGLYSHQTGCLYTGE---------GPSES *:. *. : :* * MUL_0227|M.ulcerans_Agy99 GWSGQDPTIADLLKPLGYATGQFGKNHLG--------DRNKHLPTVHGFD MMAR_4410|M.marinum_M GWSGQDPTIADLLKPLGYATGQFGKNHLG--------DRNKHLPTVHGFD Mvan_4629|M.vanbaalenii_PYR-1 GLQAEDPTIATALKAQGYATGQFGKNHLG--------DRDEFLPTMHGFD Mflv_5039|M.gilvum_PYR-GCK RIPFDTALLSEVLSENGYNTYCIGKWHLTPLEESNLAATKRHWPLSRGFE Rv0711|M.tuberculosis_H37Rv RIPADTALLPEVLAEHGYNTYCVGKWHLTPLEESNMASTKRHWPTSRGFE TH_0315|M.thermoresistible__bu RIPVDTGLISEVLAEHGWNTYCVGKWHLTPLEESNMAATKRHWPVSRGFE Mb3327c|M.bovis_AF2122/97 VRPRSCAALPRILRDNGYVTGAFGKWHLTPDNVQGAAGPFDNWPLGWGFD MAV_2989|M.avium_104 YLNDRVVALPELLRDAGYLTLMSGKWHLG--------ATIETSPWARGFE MSMEG_1228|M.smegmatis_MC2_155 GIVSWERTMGDILSEAGYATACFGKWHIG--------AEDGRWPTDHGFD MAB_4469c|M.abscessus_ATCC_199 SLAPQFPTWGTMLRQQGYRTWWWGKWHLG--------DWSDTNPEGLDAH * *: * ** *: * . . MUL_0227|M.ulcerans_Agy99 EFFG-NLCHLNAEEEPELPDYPKSDRFPVLAELNR-----------PRGV MMAR_4410|M.marinum_M EFFG-NLYHLNAEEEPELPDYPKSDRFPVLAELNR-----------PRGV Mvan_4629|M.vanbaalenii_PYR-1 EFFG-NLYHLNAEEEPENVDYPKD---PEFRKKFG-----------PRGV Mflv_5039|M.gilvum_PYR-GCK RFYG-FMGGETDQWYPDLMYDNHPVAPP-ATPEEG-----YHLSKDLADK Rv0711|M.tuberculosis_H37Rv RFYG-FLGGETDQWYPDLVYDNHPVSPP-GTPEGG-----YHLSKDIADK TH_0315|M.thermoresistible__bu RFYG-FLGGETDQWYPDLVHDNHPVAPP-ATPEDG-----YHLSKDLADK Mb3327c|M.bovis_AF2122/97 HFWG-FPSGAAGQYDPIISQDNSVIGIPEGSGEDGR---PYYFPDDLTDK MAV_2989|M.avium_104 RSFA-LLPAGASHYGGSGARGFSPVPTLYTEDDRFVSVGDDFYSSDSYTD MSMEG_1228|M.smegmatis_MC2_155 EWYG-PARTYDECLWPDDPWYDGERDGYSYMYEGT--------------- MAB_4469c|M.abscessus_ATCC_199 GFSGGTFPSPNGMPNQGLQKDPGIVDQFAGWFDAEAG-------KGPWCT . MUL_0227|M.ulcerans_Agy99 LRCWATEEVSDEPDDPKYGPVGKQRIVDTGPLTKQRMETIDDETTEACVD MMAR_4410|M.marinum_M LRCWATEEVSDEPDDPKYGPVGKQRIVDTGPLTKQRMETIDDETTEACVD Mvan_4629|M.vanbaalenii_PYR-1 IRAWANGD-------------GTQRIEDTGPLTRKRMETCDEEFRDAAID Mflv_5039|M.gilvum_PYR-GCK TIEFIRDSKVIAPDKPWFSYVCPGAGHAPHHVFKEWADRYAGRFDMGYEA Rv0711|M.tuberculosis_H37Rv TIEFIRDAKVIAPDKPWFSYVCPGAGHAPHHVFKEWADRYAGRFDMGYER TH_0315|M.thermoresistible__bu TIEFIRDAKVIAPDKPWFTYLCPGAGHAPHHAPRDWADRYAGRFDMGYER Mb3327c|M.bovis_AF2122/97 AIEWLHTVRAQNATKPWMLYYATGATHAPHHVFKEWADKYRGEFDDGWDV MAV_2989|M.avium_104 TLLRYLDERAPDDDRPFFAYLPFQAPHWPLQAPDESIAKYRGRYDEGPDV MSMEG_1228|M.smegmatis_MC2_155 --------------------KADGVHATDQQLTVKLKGEMDGEYDRRAKA MAB_4469c|M.abscessus_ATCC_199 TVSLVN---------------PHDICWWPKNPLPEDVPHWFDGLPVNFQT . MUL_0227|M.ulcerans_Agy99 FIKRQAAADTPFFVWMNMTHMHLR-----------------------THT MMAR_4410|M.marinum_M FIKRQAAADTPFFVWMNMTHMHLR-----------------------THT Mvan_4629|M.vanbaalenii_PYR-1 FIKRQHEADTPFFVWFNSTHMHFR-----------------------THP Mflv_5039|M.gilvum_PYR-GCK YREIVLENQKRLGLVPPDTELSAVNPYLDVKGPDGQDWPAQDTVRPWDSL Rv0711|M.tuberculosis_H37Rv YREIVLERQKALGIVPPDTELSPINPYLDVPGPNGETWPLQDTVRPWDSL TH_0315|M.thermoresistible__bu YREVVLENQKKLGIVPPDTELPPINPYQDVKGPHGEPWPLQDTVRPWDSL Mb3327c|M.bovis_AF2122/97 YRQKTFERQKRLGIIPPDAELTER----------------PDLFPAWDSM MAV_2989|M.avium_104 LRAERLAALKRLGLCPPDVTPHPV---------------VADGAPEWADM MSMEG_1228|M.smegmatis_MC2_155 FMKRSVEADKPFFLYHNHSLMHFP-------------------------M MAB_4469c|M.abscessus_ATCC_199 PDELRQHGKPRLQIDYANFMSPIMTG-------------------AVTYS : : MUL_0227|M.ulcerans_Agy99 KPESVGQAGVWQSPYHDTMIDHDRNVGQLLDALDELGIAQDTIVIYST-D MMAR_4410|M.marinum_M KPESVGQAGVWQSPYHDTMIDHDRNVGQLLDALDELGIAQDTIVIYST-D Mvan_4629|M.vanbaalenii_PYR-1 KPESIGRSGRWQSEYHDTMLDHDDIVGDLLNTLDELGIADGTIVMYST-D Mflv_5039|M.gilvum_PYR-GCK SEDEKRLFARMAEVFAGFLSYTDAQIGRVLDYLEESGQLDNTVIVVIS-D Rv0711|M.tuberculosis_H37Rv SDEEKKLFCRMAEVFAGFLSYTDAQIGRILDYLEESGQLDNTIIVVIS-D TH_0315|M.thermoresistible__bu SDAEKRLFCRMAEVFAGFLSYTDHQIGRVLDYLEESDQLDNTLIVVLS-D Mb3327c|M.bovis_AF2122/97 SEAQKRLFARQMEVFAGFSENADWNVGRLLDAIEDLGESDNTLVFYIWGD MAV_2989|M.avium_104 TDEERARSARTMEVYAGMVDRMDYNVGRVIDYLSRSGELDNTVVIFLS-D MSMEG_1228|M.smegmatis_MC2_155 EVREEFKGKSTNGQWGDSLLMLDYDFGSILDYLAELGIEDNTIVIMAG-D MAB_4469c|M.abscessus_ATCC_199 GPDMARQWARCLDMYLWLQQQVDAQIGRVLDKLASRPEIDGNTIVVFTSD : * .* ::: : :.. :. * MUL_0227|M.ulcerans_Agy99 NGPHAN-------------------------------------------- MMAR_4410|M.marinum_M NGPHAN-------------------------------------------- Mvan_4629|M.vanbaalenii_PYR-1 NGPHMN-------------------------------------------- Mflv_5039|M.gilvum_PYR-GCK NGASGEGGPNGSVNEVKFFNGYIDSAEESLKVFDELGGPQTYN------H Rv0711|M.tuberculosis_H37Rv NGASGEGGPNGSVNEGKFFNGYIDTVAESMKLFDHLGGPQTYN------H TH_0315|M.thermoresistible__bu NGASGEGGPDGSVNEVKFFNGYVDTVEESMRFYDQLGGPQTYN------H Mb3327c|M.bovis_AF2122/97 NGASMEGTNTGSFNEMTFLNGLDLDAERQLELIEQYGGIAALGDEFTAPH MAV_2989|M.avium_104 NGAEGAIVEAMPLRGPQIAAQIEKHCDNSLDNLGRPTSFIWYG------- MSMEG_1228|M.smegmatis_MC2_155 NGAEDH-------------------------------------------- MAB_4469c|M.abscessus_ATCC_199 HGEYAG-------------------------------------------- :* MUL_0227|M.ulcerans_Agy99 ---TWPDGATTPFRSEK-NTNWEGALRIPEMIRWPGKISAG---VVSNEI MMAR_4410|M.marinum_M ---TWPDGATTPFRSEK-NTNWEGAFRIPEMIRWPGKISAG---VVSNEI Mvan_4629|M.vanbaalenii_PYR-1 ---SWPDAGMTPFRNEK-NSNWEGAYRVPAVVRWPGRIPAG---TVLNGI Mflv_5039|M.gilvum_PYR-GCK YPIGWAMAFNTPYKLFKRYASHEGGIADTAIISWPKGIAAHG--EIRDNY Rv0711|M.tuberculosis_H37Rv YPIGWAMAFNTPYKLFKRYASHEGGIADPAIISWPNGIAAHG--EIRDNY TH_0315|M.thermoresistible__bu YPTGWAMAFNTPYKLFKRYASHEGGIADPAIISWPNGITARD--AVCDRY Mb3327c|M.bovis_AF2122/97 FASAWAHASNTPLQWGKQMASHLGGTRDPLVVAWPARIRPDG--RVRSQF MAV_2989|M.avium_104 --PRWAQAATAPSRLHKAFTTQGG-IRVPGFITWPG-FARQG--QIGTAF MSMEG_1228|M.smegmatis_MC2_155 ----LAGRGTAGFFDGSYFSSAEGGIRTPCLIRWPGKVVPR----ESNEM MAB_4469c|M.abscessus_ATCC_199 ----------SHGLRGKGATAYEEAIRVPLYIRDPQGVLTPKPGETRTQL : . : . : * . MUL_0227|M.ulcerans_Agy99 IQHHDRLPTFLAAAGEPDIIEKLKKGHKISVRGDDKEFKVHLDAFNLLPY MMAR_4410|M.marinum_M IQHHDWLPTFLAAAGEPDIIEKLKKGHKISVRGDDKEFKVHLDAFNLLPY Mvan_4629|M.vanbaalenii_PYR-1 VSHNDWFVTLLAAAGDPDIAERLRAGTDLNG----TTYKVHLDGHNQLDY Mflv_5039|M.gilvum_PYR-GCK VNVADITPTVYDLLDITPP-ATVRG-----------VAQKPLDGVSFKVA Rv0711|M.tuberculosis_H37Rv VNVSDITPTVYDLLGMTPP-GTVKG-----------IPQKPMDGVSFIAA TH_0315|M.thermoresistible__bu INVVDVTPTVYELIGLTPP-DTVRG-----------VRQRPLEGVSFRAA Mb3327c|M.bovis_AF2122/97 THCIDIAPTVLAAIGLPEP-THVDG-----------FEQEPMDGTSFVRT MAV_2989|M.avium_104 STVMDIAPTLLELAGTSHPGTAYRG-----------REVAPMRGRSLVGY MSMEG_1228|M.smegmatis_MC2_155 VHVTDMFPTLLRWVGCDIP------------------DDRIIDGIDQREF MAB_4469c|M.abscessus_ATCC_199 TSSVDLAPLLLTIGSGGNAWRSDPRFSYLAAR--ADIAAIAKNNAAGRKW * . . MUL_0227|M.ulcerans_Agy99 LTGEVEESPRQGFIYFSDDCDVLGIRFHNWKIVFQEQRCQG--------- MMAR_4410|M.marinum_M LTGEVEESPRQGFIYFSDDCDVLGIRFHNWKIVFQEQRCQG--------- Mvan_4629|M.vanbaalenii_PYR-1 LTGATDESPRQYFFYVSDDGDLTALRYDNWKIVFLEQRAAG--------- Mflv_5039|M.gilvum_PYR-GCK LE--NPNAPTGKETQFYTMLGTRGIWHRGWFANTVHAASPAGWS------ Rv0711|M.tuberculosis_H37Rv LA--DPAADTGKTTQFYTMLGTRGIWHEGWFANTIHAATPAGWS------ TH_0315|M.thermoresistible__bu LA--DPDADTGKRTQFYSMLGTRGIWSDGWFANTVHAASPAGWS------ Mb3327c|M.bovis_AF2122/97 FD--DAEAEDRHTVQYFENFGSRAIYKDGWWACARLDKAPWDLSPETMRR MAV_2989|M.avium_104 LSGAADTVHDADTETGWELFGRRAIRQGNWKALHLPAP------------ MSMEG_1228|M.smegmatis_MC2_155 FSG--AEESNRDGCMVWLNEELHAVKWSQFKINFKRQQ------------ MAB_4469c|M.abscessus_ATCC_199 IAHVTDDMSVEEMATLLKDPRIRAVMGENAPTEIPTSAASHIVAVR---- : .: MUL_0227|M.ulcerans_Agy99 --------TLQVWAEPFIPLRVPKIFNLRTDPYERADITSNTYYDWFLDH MMAR_4410|M.marinum_M --------TLQVWAEPFVPLRVPKIFNLRTDPFERADITSNTYYDWFLDH Mvan_4629|M.vanbaalenii_PYR-1 --------TLQVWLEPYTELRAPKLFNLRTDPYERADITSNTYFDWVLDR Mflv_5039|M.gilvum_PYR-GCK ------HFDDDRWELYHVDADRSQVHDLAAEYPEKLDELKALWFSEAQKY Rv0711|M.tuberculosis_H37Rv ------NFNADRWELFHIAADRSQCHDLAAEHPDKLEELKALWFSEAAKY TH_0315|M.thermoresistible__bu ------NFDADRWELYHLESDRSQSRDLAAEHPEKLEELKQLWFDEAAKY Mb3327c|M.bovis_AF2122/97 FAPGTYDPDQDVWELYYLPDDFSQAKNLAAEHPDKVAELTQLWWQEAERN MAV_2989|M.avium_104 -------YGPGSWQLYDLASDPGEVDDLAAARPDKLAELLALWDRYVEET MSMEG_1228|M.smegmatis_MC2_155 -----------HFHDPEVPLGFARITNLLEDPKEREPVNQTWVRWWVMQH MAB_4469c|M.abscessus_ATCC_199 -TAEAKLANYSYWKPGGMRIDTSRPSEHEFYDYSTPSGKQESQNQAGDST : . : . MUL_0227|M.ulcerans_Agy99 DFIAFYGTAICTQFLETFKEFPPRHPPARFTIDQAVEKLQAIVKD----- MMAR_4410|M.marinum_M DFIAFYGTAICTQFLETFKEFPPRHPPASFTIDQAVEKLQAIVKD----- Mvan_4629|M.vanbaalenii_PYR-1 VFVFTPAQAFVAQMLQTLVEFPQRQASASFNLEQVMAKLQAGIPDS---- Mflv_5039|M.gilvum_PYR-GCK NGLPLGDLDIFETMSRWRPTLSGERSAYVYYPGTADVGIGAVVELRGRSF Rv0711|M.tuberculosis_H37Rv NGLPLADLNLLETMTRSRPYLVSERASYVYYPDCADVGIGAAVEIRGRSF TH_0315|M.thermoresistible__bu NGLPLGDLNLFETLGRWRPHLSRGRTSYTYYPGTAEVGLGAAVDIRGQSF Mb3327c|M.bovis_AF2122/97 RVLPL--LGGLAVMFGDLPPLP-TTARFSFKGDVQNIQRGMVPRICGRSY MAV_2989|M.avium_104 G-VILDPISVFDAEL----------------------------------- MSMEG_1228|M.smegmatis_MC2_155 AYRFIQEFEASVEKEQLIPAGAPLDFVPARNP------------------ MAB_4469c|M.abscessus_ATCC_199 KQAQLQALIDNEVLPEVQAPLPAFLGQAQEQGLADMQKLMVLRGG----- MUL_0227|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4410|M.marinum_M -------------------------------------------------- Mvan_4629|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_5039|M.gilvum_PYR-GCK AVLAEVEVDPGGANGVVVKHGGAHGGYVMYLQGGR-LHFCYNFLGEYEQT Rv0711|M.tuberculosis_H37Rv AVLADVTIDTTGAEGVLFKHGGAHGGHVLFVRDGR-LHYVYNFLGERQQL TH_0315|M.thermoresistible__bu TVLADVTVDAAGAQGVIVKHGAGHGGYVLFLQDGR-LHFVYNFMGEEEQR Mb3327c|M.bovis_AF2122/97 AIEARLHIPDGGAQGVIVANADFMGGFALWVDEQRHLHHTYSFLGVETYR MAV_2989|M.avium_104 -------------------------------------------------- MSMEG_1228|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4469c|M.abscessus_ATCC_199 -------------------------------------------------- MUL_0227|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4410|M.marinum_M -------------------------------------------------- Mvan_4629|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_5039|M.gilvum_PYR-GCK LAAPDPVPPGLHTLGFTYTVTGTAEGSHTPIGDAELFLDTERVASLAEMR Rv0711|M.tuberculosis_H37Rv VSSSGPVPSGRHLLGVRYLRTGTVPNSHTPVGDLELFFDENLVGALTNVL TH_0315|M.thermoresistible__bu VSSADPIPAGRHILGVSYHRTGTVDGSHTPLGEVALYVDGTVVATRPDVR Mb3327c|M.bovis_AF2122/97 QVSSEPLPTGDVTVRMLFDSHQPVAASG---GRVTLWADDRLIGEGELPQ MAV_2989|M.avium_104 -------------------------------------------------- MSMEG_1228|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4469c|M.abscessus_ATCC_199 -------------------------------------------------- MUL_0227|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4410|M.marinum_M -------------------------------------------------- Mvan_4629|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_5039|M.gilvum_PYR-GCK SQPGTFGLAGASLSVGRNNGSPVSEAYH--PPFAFAGGRIARVNIDTS-- Rv0711|M.tuberculosis_H37Rv THPGTFGLAGAAISVGRNGGSAVSSHYE--APFAFTGGTITQVTVDVS-- TH_0315|M.thermoresistible__bu AHPANFGLAGGGIAVGRNTGQPVSSAYR--APFAFTGGSIAKVIVDIS-- Mb3327c|M.bovis_AF2122/97 TVPLAF-TSYAGMDIGRDNGLVVDRGYEDKAPYAFTG-TVTEVIFDLKPV MAV_2989|M.avium_104 -------------------------------------------------- MSMEG_1228|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4469c|M.abscessus_ATCC_199 -------------------------------------------------- MUL_0227|M.ulcerans_Agy99 ----------------------- MMAR_4410|M.marinum_M ----------------------- Mvan_4629|M.vanbaalenii_PYR-1 ----------------------- Mflv_5039|M.gilvum_PYR-GCK --GAPYVDLERDFARAFARD--- Rv0711|M.tuberculosis_H37Rv --GRPFEDVESDLALAFSRD--- TH_0315|M.thermoresistible__bu --GTPYRDVEREAAMAFARD--- Mb3327c|M.bovis_AF2122/97 HPEAARALHEHASVQAVGQGAAG MAV_2989|M.avium_104 ----------------------- MSMEG_1228|M.smegmatis_MC2_155 ----------------------- MAB_4469c|M.abscessus_ATCC_199 -----------------------