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M. ulcerans Agy99 MUL_2658 (atsB)

annotation: arylsulfatase AtsB (aryl-sulfate sulphohydrolase)
coordinates: 2970265 - 2973156
length: 963

SEENTLVIVAGYQDLDAAQHDFENLTGRANAKTLPLQGAVLVGKDNEGNPVLIDTGNRLGRRGAAWGAGA
GLAVGLVSPALLASTAVGAAAGALAGTFIQHRVKSGLADKIGQALSAGSAVVIAVTPAQGRLPVEQTLSG
SPMKSVAELSRSTMRSLGAALQEAMGKFNPDRTKLPIPQRTIGRTMAESVGDWTIVAGANAPDDAPNVLI
VLIDDAGFGGPDTFGGGIRTPTLSRVANNGLAYNRFHLTAICSPTRAALLTGRNHHRVGFGSVCELPGPY
PGYSTVKPRSCAALPRILRDNGYVTGAFGKWHLTPDNVQGAAGPFDNWPLGWGFDHFWGFPSGAAGQYDP
IITQDNSVLGIPQGDDGKPYFFPDDLTDKAIEWLHTVRAQNATKPWLLYYSTGATHAPHHVFKEWADKYQ
GQFDEGWDVYRQKTFERQKELGIIPPDAELTERPDLFPAWDSLSEAQQKLFARQMEVFAGFSENADWNVG
RLLDAIDGLGESDNTLVFYIWGDNGASMEGTNTGSFNEMTFLNGLDLDAERQLELIEQYGGIEALGDEFT
APHFASAWAHANNTPFQWGKQMASHLGGTRDPMVACWPSRIPREGGIRSQFTHCIDIAPTVLQAIGLPEP
TSVDGFEQEPMDGTSFVHTFDDAQAEERHTVQYFENFGSRSIYQDGWWACARLDKAPWDLSPQTMARFSP
GNYDPEKDVWELYYLPDDFSQARNVAAEHPDKLAELRELWWQEAERNRVLPLLGGLAVMYGELPPLPTIT
RFAFQGGVQNIQRGMVPRVFGRSYAIEARPHIPDGGAEGVIVANADFMGGFALWVDEQRRLHHTYSFLGI
ETYRQVSTEPVPTGDVTVRMLFESEAPVVGSGGRVTLWANDRLIGEGELPQTVTLAFTSYAGLDVGRDNG
LVVDRDYEDKALYMFSGTVKEVVFDLKPVHPDAEKALHEHASIQAVGQGAAG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_2658atsB-100% (963)arylsulfatase AtsB (aryl-sulfate sulphohydrolase)
M. ulcerans Agy99MUL_2500atsD_1e-17444.41% (734) arylsulfatase AtsD_1
M. ulcerans Agy99MUL_0454atsDe-17142.26% (807) arylsulfatase AtsD

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3327catsB0.085.04% (969) arylsulfatase AtsB
M. gilvum PYR-GCKMflv_5039-1e-13236.27% (761) sulfatase
M. tuberculosis H37RvRv3299catsB0.085.14% (969) arylsulfatase AtsB
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4307-1e-13637.30% (764) arylsulfatase AtsA
M. marinum MMMAR_1232atsB0.098.76% (967) arylsulfatase AtsB (aryl-sulfate sulphohydrolase)
M. avium 104MAV_4461-1e-13336.71% (790) arylsulfatase
M. smegmatis MC2 155MSMEG_1451-1e-13236.00% (775) arylsulfatase
M. thermoresistible (build 8)TH_0315-1e-13335.50% (783) arylsulfatase
M. vanbaalenii PYR-1Mvan_4467-1e-17243.06% (757) sulfatase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5039|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_1451|M.smegmatis_MC2_155      --------------------------------------------------
MAV_4461|M.avium_104                --------------------------------------------------
TH_0315|M.thermoresistible__bu      --------------------------------------------------
MAB_4307|M.abscessus_ATCC_1997      --------------------------------------------------
MUL_2658|M.ulcerans_Agy99           -MSEENTLVIVAGYQDLDAAQHDFENLTGRANAKTLPLQGAVLVGKDNEG
MMAR_1232|M.marinum_M               -MSEENTLVIVAGYQDLDAAQHDFENLTGRANAKTLPLQGAVLVGKDNEG
Mb3327c|M.bovis_AF2122/97           MMSEDNALVLVAGYQDLDSARHDFQTLVDAAKDKSIPLQGAVLIGKDAEG
Rv3299c|M.tuberculosis_H37Rv        MMSEDNALVLVAGYQDLDSARHDFQTLVDAAKDKSIPLQGAVLIGKDAEG
Mvan_4467|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mflv_5039|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_1451|M.smegmatis_MC2_155      --------------------------------------------------
MAV_4461|M.avium_104                --------------------------------------------------
TH_0315|M.thermoresistible__bu      --------------------------------------------------
MAB_4307|M.abscessus_ATCC_1997      -------------MHIPGDDAPEPEQNAERGRLTRRSMLGGIAAAGMGVA
MUL_2658|M.ulcerans_Agy99           NPVLIDTGNRLGRRGAAWGAGAGLAVGLVSPALLASTAVGAAAGALAGTF
MMAR_1232|M.marinum_M               NPVLIDTGNRLGRRGAAWGAGAGLAVGLFSPALLASTAVGAAAGALAGTF
Mb3327c|M.bovis_AF2122/97           SPVLVDTGNRLGRRGAAWGAGVGLAIGLFSPALLASAALGAATGALAGTF
Rv3299c|M.tuberculosis_H37Rv        SPVLVDTGNRLGRRGAAWGAGVGLAIGLFSPALLASAALGAATGALAGTF
Mvan_4467|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mflv_5039|M.gilvum_PYR-GCK          -------------------------MTTEFNG------------------
MSMEG_1451|M.smegmatis_MC2_155      -------------------------MAAEFNG------------------
MAV_4461|M.avium_104                -------------------MVAGSGQSAEFSG------------------
TH_0315|M.thermoresistible__bu      --------------------------MADFGG------------------
MAB_4307|M.abscessus_ATCC_1997      AASALVAGCDDDSSSRTDRSSAAEEANAGFNG------------------
MUL_2658|M.ulcerans_Agy99           IQHRVKSGLADKIGQALSAGSAVVIAVTPAQGRLPVEQTLSGSPMKSVAE
MMAR_1232|M.marinum_M               IQHRVKSGLADKIGQALSAGSAVVIAVTPAQGRLPVEQTLSGSPMKSVAE
Mb3327c|M.bovis_AF2122/97           AHHRIKTGLADKIGQALAAGRAVVIAVTEAQGRLEAGQALASSPMKSVAE
Rv3299c|M.tuberculosis_H37Rv        AHHRIKTGLADKIGQALAAGRAVVIAVTEAQGRLEAGQALASSPMKSVAE
Mvan_4467|M.vanbaalenii_PYR-1       -------------------MRRDILPIPDPQ-------------------
                                                               .                      

Mflv_5039|M.gilvum_PYR-GCK          -------KIALDIRDSEPDWGPFAAPT-----------------------
MSMEG_1451|M.smegmatis_MC2_155      -------KIELDIRDSEPDWGPFAAPT-----------------------
MAV_4461|M.avium_104                -------RVELDIRDSEPDWGPYAAPT-----------------------
TH_0315|M.thermoresistible__bu      -------KIELDIRDSEPDWGPFAAPT-----------------------
MAB_4307|M.abscessus_ATCC_1997      -------KIELDVRDSKPDWTPYELKH-----------------------
MUL_2658|M.ulcerans_Agy99           LSRSTMRSLGAALQEAMGKFNPDRTKLPIPQR----TIGRTMAESVGDWT
MMAR_1232|M.marinum_M               LSRSTMRSLGAALQEAMGKFNPDRTKLPIPQRSFGGTIGRTMAESVGDWT
Mb3327c|M.bovis_AF2122/97           LSRSTLRSLGAALREAMGKFNPDRTRLPLPQRRFGGVVGRTMAESVGDWS
Rv3299c|M.tuberculosis_H37Rv        LSRSTLRSLGAALREAMGKFNPDRTRLPLPQRRFGGVVGRTMAESVGDWS
Mvan_4467|M.vanbaalenii_PYR-1       -------HVGLTTYDAK---DPDTTYPPITPLR-----------------
                                            :     ::     *                            

Mflv_5039|M.gilvum_PYR-GCK          ------AQPEAPNVLYLVWDDIGIATWDCFGGLVDMPAMSRIAERGVRLS
MSMEG_1451|M.smegmatis_MC2_155      ------AAEGAPNVLYVVWDDIGIATWDCFGGLVEMPAMSRIAEHGVRLS
MAV_4461|M.avium_104                ------APPNAPNILYLVWDDTGIATWDCFGGLVEMPAMSRIAERGVRLS
TH_0315|M.thermoresistible__bu      ------APEGAPNILYVVWDDVGIGTWDCFGGLVEMPTMSRIAEQGVRLS
MAB_4307|M.abscessus_ATCC_1997      ------APDGAPNVLVVLFDDTGMATWSPYGGRVNMPTLQRLADNGLTYS
MUL_2658|M.ulcerans_Agy99           IVAGANAPDDAPNVLIVLIDDAGFGGPDTFGGGIRTPTLSRVANNGLAYN
MMAR_1232|M.marinum_M               IVAGANAPDDAPNLLIVLIDDAGFGGPDTFGGGIRTPTLSRVANNGLAYN
Mb3327c|M.bovis_AF2122/97           IVPSPFPPDDAPNVLIVLIDDAGFGGPDTFGGAIRTPTLSRLAQNGLIYN
Rv3299c|M.tuberculosis_H37Rv        IVPGPFPPDDAPNVLIVLIDDAGFGGPDTFGGAIRTPTLSRLAQNGLIYN
Mvan_4467|M.vanbaalenii_PYR-1       ------PPQGAPNVLIVLLDDVGFGASSAFGGPCATPTAERLAANGLKLN
                                          .   ***:* :: ** *:.  . :**    *: .*:* .*:  .

Mflv_5039|M.gilvum_PYR-GCK          QFHTTALCSPTRASLLTGRNATTVGMATIEEFTDGFPNCNGRIPFDTALL
MSMEG_1451|M.smegmatis_MC2_155      QFHTTALCSPTRAALLTGRNPTTVGMATIEEFTDGFPNCSGRIPFETALL
MAV_4461|M.avium_104                QFHTTALCSPTRAALLTGRNATTVGMATIEEFTEGFPNANGRIPFDTALL
TH_0315|M.thermoresistible__bu      QFHTTALCSPTRAALLTGRNPTTVGMATIEEFTDGFPNCSGRIPVDTGLI
MAB_4307|M.abscessus_ATCC_1997      QWHTTALCSPTRSCLLTGRNHHVNRFASITEGSDGYPGAAGRLPAQCATI
MUL_2658|M.ulcerans_Agy99           RFHLTAICSPTRAALLTGRNHHRVGFGSVCELPGPYPGYSTVKPRSCAAL
MMAR_1232|M.marinum_M               RFHLTAICSPTRAALLTGRNHHRVGFGSVCELPGPYPGYSTVKPRSCAAL
Mb3327c|M.bovis_AF2122/97           RFHVTAVCSPTRAALLTGRNHHRVGFGSVCEFPGPYPGYSAVRPRSCAAL
Rv3299c|M.tuberculosis_H37Rv        RFHVTAVCSPTRAALLTGRNHHRVGFGSVCEFPGPYPGYSAVRPRSCAAL
Mvan_4467|M.vanbaalenii_PYR-1       RFHTTALCSPTRQALLTGRNHHSVGMGGVTEIATSAPGYSSIRPKDKAPV
                                    ::* **:***** .******     :. : * .   *.     * . . :

Mflv_5039|M.gilvum_PYR-GCK          SEVLSENGYNTYCIGKWHLTPLEESNLAATKRHWPLSRGFERFYGFMGGE
MSMEG_1451|M.smegmatis_MC2_155      PEVLAENGYNTYCIGKWHLTPLEESNLASTKRHWPCSRGFERFYGFMGGE
MAV_4461|M.avium_104                SEALAEHGYNTYCVGKWHLTPLEESNMASTKRHWPTSRGFERFYGFLGGE
TH_0315|M.thermoresistible__bu      SEVLAEHGWNTYCVGKWHLTPLEESNMAATKRHWPVSRGFERFYGFLGGE
MAB_4307|M.abscessus_ATCC_1997      GQVLQDNGYSTFWVGKNHNVPQEDVSCGGSKSEWPLQKGFDRYYGFLGGE
MUL_2658|M.ulcerans_Agy99           PRILRDNGYVTGAFGKWHLTPDNVQGAAGPFDNWPLGWGFDHFWGFPSGA
MMAR_1232|M.marinum_M               PRILRDNGYVTGAFGKWHLTPDNVQGAAGPFDNWPLGWGFDHFWGFPSGA
Mb3327c|M.bovis_AF2122/97           PRILRDNGYVTGAFGKWHLTPDNVQGAAGPFDNWPLGWGFDHFWGFPSGA
Rv3299c|M.tuberculosis_H37Rv        PRILRDNGYVTGAFGKWHLTPDNVQGAAGPFDNWPLGWGFDHFWGFPSGA
Mvan_4467|M.vanbaalenii_PYR-1       AETLRLNGYSTSQFGKCHEVPVWEVSPVGPFGQWPTGSGFEHFYGFIGGE
                                     . *  :*: *  .** * .*    .  ..  .**   **::::** .* 

Mflv_5039|M.gilvum_PYR-GCK          TDQWYPDLMYDNHPVAPPAT---PEEGYHLSKDLADKTIEFIRDSKVIAP
MSMEG_1451|M.smegmatis_MC2_155      TDQWYPDLTYDNHPVDPPAT---PEEGYHLSKDLADKTIEFIRDAKVVAS
MAV_4461|M.avium_104                TDQWYPDLVYDNHPVSPPAT---PEDGYHLSKDLADKTIEFIRDAKVIAP
TH_0315|M.thermoresistible__bu      TDQWYPDLVHDNHPVAPPAT---PEDGYHLSKDLADKTIEFIRDAKVIAP
MAB_4307|M.abscessus_ATCC_1997      TNNWYPDLVEDNRFIEQPTS---PEQGYHLSKDLADQALRMLRDQRNTNP
MUL_2658|M.ulcerans_Agy99           AGQYDPIITQDNSVLGIPQG--DDGKPYFFPDDLTDKAIEWLHTVRAQNA
MMAR_1232|M.marinum_M               AGQYDPIITQDNSVLGIPQG--DDGKPYFFPDDLTDKAIEWLHTVRAQNA
Mb3327c|M.bovis_AF2122/97           AGQYDPIISQDNSVIGIPEGSGEDGRPYYFPDDLTDKAIEWLHTVRAQNA
Rv3299c|M.tuberculosis_H37Rv        AGQYDPIISQDNSVIGIPEGSGEDGRPYYFPDDLTDKAIEWLHTVRAQNA
Mvan_4467|M.vanbaalenii_PYR-1       ANQYYPGLYEGTKPVEPEKT---PEQGYTLTEDLADRAITWVRQQQALTP
                                    :.:: * :  ..  :            * :..**:*:::  ::  :   .

Mflv_5039|M.gilvum_PYR-GCK          DKPWFSYVCPGAGHAPHHVFKEWADRYAGRFDMGYEAYREIVLENQKRLG
MSMEG_1451|M.smegmatis_MC2_155      DKPWFTYLCPGAGHAPHHVFKEWADRYKGRFDMGYERYREIVLENQKRMG
MAV_4461|M.avium_104                EKPWFSYVCPGAGHAPHHVFKEWADRYAGRFDMGYERYREVVLERQKAMG
TH_0315|M.thermoresistible__bu      DKPWFTYLCPGAGHAPHHAPRDWADRYAGRFDMGYERYREVVLENQKKLG
MAB_4307|M.abscessus_ATCC_1997      SKPWYMWFCPGANHAPHHSPAEYADKYRGKFDDGYEAYREWVLARMIDKG
MUL_2658|M.ulcerans_Agy99           TKPWLLYYSTGATHAPHHVFKEWADKYQGQFDEGWDVYRQKTFERQKELG
MMAR_1232|M.marinum_M               TKPWLLYYSTGATHAPHHVFKEWADKYQGQFDEGWDVYRQKTFERQKELG
Mb3327c|M.bovis_AF2122/97           TKPWMLYYATGATHAPHHVFKEWADKYRGEFDDGWDVYRQKTFERQKRLG
Rv3299c|M.tuberculosis_H37Rv        TKPWMLYYATGATHAPHHVFKEWADKYRGEFDDGWDVYRQKTFERQKRLG
Mvan_4467|M.vanbaalenii_PYR-1       DKPFFMYFAPGATHAPHHVPKQWSDKYRGKFDDGWDVLRESMLDNQKALG
                                     **:  : ..** *****   :::*:* *.** *::  *:  : .    *

Mflv_5039|M.gilvum_PYR-GCK          LVPPDTELSAVNPYLDVKGPDGQDWPAQDTVRPWDSLSEDEKRLFARMAE
MSMEG_1451|M.smegmatis_MC2_155      LVPPDTELSPVNPYSEVTGPDGQPWPAQDTVRPWDSLSDDEKALFCRMAE
MAV_4461|M.avium_104                IVPSDTELSPVNPYLDVTGPSGEPWPLQDTVRPWDSLNDEEKKLFARMAE
TH_0315|M.thermoresistible__bu      IVPPDTELPPINPYQDVKGPHGEPWPLQDTVRPWDSLSDAEKRLFCRMAE
MAB_4307|M.abscessus_ATCC_1997      IMPRETKLTPINPLPNDVAVEA------DSVRPWNTLNPDEKRLFSRMAE
MUL_2658|M.ulcerans_Agy99           IIPPDAELTERP----------------DLFPAWDSLSEAQQKLFARQME
MMAR_1232|M.marinum_M               IIPPDAELTERP----------------DLFPAWDSLSEAQQKLFARQME
Mb3327c|M.bovis_AF2122/97           IIPPDAELTERP----------------DLFPAWDSMSEAQKRLFARQME
Rv3299c|M.tuberculosis_H37Rv        IIPPDAELTERP----------------DLFPAWDSMSEAQKRLFARQME
Mvan_4467|M.vanbaalenii_PYR-1       VVPEDAQLTARH----------------DEIPAWDDMPDVLKPVLARQME
                                    ::* :::*.                   * . .*: :    : ::.*  *

Mflv_5039|M.gilvum_PYR-GCK          VFAGFLSYTDAQIGRVLDYLEESGQLDNTVIVVIS-DNGASGEGGPNGSV
MSMEG_1451|M.smegmatis_MC2_155      VFAGFLSYTDAQIGRVLDYLEESGQIDNTIIVVIS-DNGASGEGGPNGSV
MAV_4461|M.avium_104                VFAGFLSYTDAQIGRILDYLEESGQLDDTIIVVIS-DNGASGEGGPNGSV
TH_0315|M.thermoresistible__bu      VFAGFLSYTDHQIGRVLDYLEESDQLDNTLIVVLS-DNGASGEGGPDGSV
MAB_4307|M.abscessus_ATCC_1997      VFAGFSEYTDAQVGRVIDYLEQTGQLDNTVVFYCA-DNGASGEGSPNGSV
MUL_2658|M.ulcerans_Agy99           VFAGFSENADWNVGRLLDAIDGLGESDNTLVFYIWGDNGASMEGTNTGSF
MMAR_1232|M.marinum_M               VFAGFSENADWNVGRLLDAIDGLGESDNTLVFYIWGDNGASMEGTNTGSF
Mb3327c|M.bovis_AF2122/97           VFAGFSENADWNVGRLLDAIEDLGESDNTLVFYIWGDNGASMEGTNTGSF
Rv3299c|M.tuberculosis_H37Rv        VFAGFSENADWNVGRLLDAIEDLGESDNTLVFYIWGDNGASMEGTNTGSF
Mvan_4467|M.vanbaalenii_PYR-1       IYAGFLEQTDHEIGRLVDAIDDLGALDNTLIYYIIGDNGASAEGTPNGCF
                                    ::*** . :* ::**::* ::  .  *:*::     ***** **   *..

Mflv_5039|M.gilvum_PYR-GCK          NEVKFFNGYID--SAEESLKVFDELGGPQTYN------HYPIGWAMAFNT
MSMEG_1451|M.smegmatis_MC2_155      NETKFFNGYID--TAEEGLKFIDKLGGPQTYN------HYPIGWAMAFNT
MAV_4461|M.avium_104                NEGKFFNGYID--TVEESMKLFDQLGGPQTYN------HYPIGWAMAFNT
TH_0315|M.thermoresistible__bu      NEVKFFNGYVD--TVEESMRFYDQLGGPQTYN------HYPTGWAMAFNT
MAB_4307|M.abscessus_ATCC_1997      NENKFFNGYPD--DLAENMKYIDRLGTPDTYN------HYPTGWAVAFST
MUL_2658|M.ulcerans_Agy99           NEMTFLNGLD--LDAERQLELIEQYGGIEALGDEFTAPHFASAWAHANNT
MMAR_1232|M.marinum_M               NEMTFLNGLD--LDAERQLELIEQYGGIEALGDEFTAPHFASAWAHANNT
Mb3327c|M.bovis_AF2122/97           NEMTFLNGLD--LDAERQLELIEQYGGIAALGDEFTAPHFASAWAHASNT
Rv3299c|M.tuberculosis_H37Rv        NEMTFLNGLD--LDAERQLELIEQYGGIAALGDEFTAPHFASAWAHASNT
Mvan_4467|M.vanbaalenii_PYR-1       NEMCTLNGLAGIETPEFLLSKIDDFGTPDAYN------HYAVGWAHALCG
                                    **   :**          :   :  *   : .      *:. .** *   

Mflv_5039|M.gilvum_PYR-GCK          PYKLFKRYASHEGGIADTAIISWPKGIAAHGEIRDNYVNVADITPTVYDL
MSMEG_1451|M.smegmatis_MC2_155      PYKLFKRYASHEGGIADPAIISWPKGIAARGEVRDNYVNVCDVTPTVYDM
MAV_4461|M.avium_104                PYKLYKRYASHEGGIADTAIISWPNGIAAHGEIRDNYVNVCDITPTVYDL
TH_0315|M.thermoresistible__bu      PYKLFKRYASHEGGIADPAIISWPNGITARDAVCDRYINVVDVTPTVYEL
MAB_4307|M.abscessus_ATCC_1997      PFQMFKRYSQFSGGTCDPLVIHWPKGIKAKGEVRHQYHHVTDIVPTILDV
MUL_2658|M.ulcerans_Agy99           PFQWGKQMASHLGGTRDPMVACWPSRIPREGGIRSQFTHCIDIAPTVLQA
MMAR_1232|M.marinum_M               PFQWGKQMASHLGGTRDPMVVCWPSRIPREGGIRSQFTHCIDIAPTVLQA
Mb3327c|M.bovis_AF2122/97           PLQWGKQMASHLGGTRDPLVVAWPARIRPDGRVRSQFTHCIDIAPTVLAA
Rv3299c|M.tuberculosis_H37Rv        PLQWGKQMASHLGGTRDPLVVAWPARIRPDGRVRSQFTHCIDIAPTVLAA
Mvan_4467|M.vanbaalenii_PYR-1       PYQWTKQVASHWGGTRNGTIVHWPNGIAAKGETRNQFHHVIDVVPTILEA
                                    * :  *: :.. **  :  :  **  *   .    .: :  *:.**:   

Mflv_5039|M.gilvum_PYR-GCK          LDITPPATVRGVAQKPLDGVSFKVALENPNAPTGKETQFYTMLGTRGIWH
MSMEG_1451|M.smegmatis_MC2_155      LGITPPATVRGVPQKPLDGVSFKAALADPDAPTGKETQFYAMLGTRGIWH
MAV_4461|M.avium_104                LGMSPPETVKGIAQKPLDGVSFKAALDDPNADTGKTTQFYTMLGTRGIWH
TH_0315|M.thermoresistible__bu      IGLTPPDTVRGVRQRPLEGVSFRAALADPDADTGKRTQFYSMLGTRGIWS
MAB_4307|M.abscessus_ATCC_1997      AGLTMPETYRGVDQFPVNGVSMRYTFDDKDAATTKKRQYYAMLGTRGIWE
MUL_2658|M.ulcerans_Agy99           IGLPEPTSVDGFEQEPMDGTSFVHTFDDAQAEERHTVQYFENFGSRSIYQ
MMAR_1232|M.marinum_M               IGLPEPTSVDGFEQEPMDGTSFVHTFDDAQAEERHTVQYFENFGSRSIYQ
Mb3327c|M.bovis_AF2122/97           IGLPEPTHVDGFEQEPMDGTSFVRTFDDAEAEDRHTVQYFENFGSRAIYK
Rv3299c|M.tuberculosis_H37Rv        IGLPEPTHVDGFEQEPMDGTSFVRTFDDAEAEDRHTVQYFENFGSRAIYK
Mvan_4467|M.vanbaalenii_PYR-1       AKLPAPTVVNSIQQAPLEGVSMMSTLRDRDADETHTVQYFEMFGNRGIYH
                                      :. *    .. * *::*.*:  :: : :*   :  *::  :*.*.*: 

Mflv_5039|M.gilvum_PYR-GCK          RGWFANTVHAASPAGWS------------HFDDDRWELYHVDADRSQVHD
MSMEG_1451|M.smegmatis_MC2_155      KGWFANTVHAATPSGWG------------HFADDRWELFHIDADRSQCHD
MAV_4461|M.avium_104                EGWFANTVHAATPAGWS------------HFDADRWELFHIEADRSQCHD
TH_0315|M.thermoresistible__bu      DGWFANTVHAASPAGWS------------NFDADRWELYHLESDRSQSRD
MAB_4307|M.abscessus_ATCC_1997      DGWKASALHAP-ISGKG------------HFDQDKWELFHVDEDRSESTD
MUL_2658|M.ulcerans_Agy99           DGWWACARLDKAPWDLSPQTMARFSPGNYDPEKDVWELYYLPDDFSQARN
MMAR_1232|M.marinum_M               DGWWACARLDKAPWDLSPQTMARFSPGNYDPEKDVWELYYLPDDFSQARN
Mb3327c|M.bovis_AF2122/97           DGWWACARLDKAPWDLSPETMRRFAPGTYDPDQDVWELYYLPDDFSQAKN
Rv3299c|M.tuberculosis_H37Rv        DGWWACARLDKAPWDLSPETMRRFAPGTYDPDQDVWELYYLPDDFSQAKN
Mvan_4467|M.vanbaalenii_PYR-1       KGWTAVT-KHRTPWIADQPPL----------DEDVWELY-APDDWTQAHD
                                     ** * :         .                * ***:    * ::  :

Mflv_5039|M.gilvum_PYR-GCK          LAAEYPEKLDELKALWFSEAQKYNGLPLGDLDIFETMSR--WRPTLSGER
MSMEG_1451|M.smegmatis_MC2_155      LAAEHPDRLEELKALWFSEADKYNGLPLGDLSILETTTR--WRPYLTGER
MAV_4461|M.avium_104                LAAENPDKLEELKALWFAEAARYNGLPLSDLNILETMTR--SRPYLVGER
TH_0315|M.thermoresistible__bu      LAAEHPEKLEELKQLWFDEAAKYNGLPLGDLNLFETLGR--WRPHLSRGR
MAB_4307|M.abscessus_ATCC_1997      LADQHPDKLKALIDAWFEEADNNFVLPLDDRLPTELLTI--ERPQFEPRR
MUL_2658|M.ulcerans_Agy99           VAAEHPDKLAELRELWWQEAERNRVLPLLGGLAVMYG----ELPPLP-TI
MMAR_1232|M.marinum_M               VAAEHPDKLAELRELWWQEAERNRVLPLLGGLAVMYG----ELPPLP-TT
Mb3327c|M.bovis_AF2122/97           LAAEHPDKVAELTQLWWQEAERNRVLPLLGGLAVMFG----DLPPLP-TT
Rv3299c|M.tuberculosis_H37Rv        LAAEHPDKVAELTQLWWQEAERNRVLPLLGGLAVMFG----DLPPLP-TT
Mvan_4467|M.vanbaalenii_PYR-1       LAAEQPERLAALQRLWLIEAVKYNVVPLDDRSFERFNPDIAGRPQLI-KG
                                    :* : *:::  *   *  ** .   :** .             * :    

Mflv_5039|M.gilvum_PYR-GCK          SAYVYYPGTADVGIGAVVELRGRSFAVLAEVEVDPGGANGVVVKHGGAHG
MSMEG_1451|M.smegmatis_MC2_155      TSYTYYPHTAEVGMGAVVELRGQSFKVLAEVTVDSAEAQGVIFKHGGAHG
MAV_4461|M.avium_104                DSYVYYPDCADVGIGAAAEIRGRSFSVLAEATVDTTGAEGVLFKQGGAHG
TH_0315|M.thermoresistible__bu      TSYTYYPGTAEVGLGAAVDIRGQSFTVLADVTVDAAGAQGVIVKHGAGHG
MAB_4307|M.abscessus_ATCC_1997      NRYLYYPDASPVPEGVAVNIRGKSYKIVANTDIS-AQAQGVIFAHGSRFG
MUL_2658|M.ulcerans_Agy99           TRFAFQGGVQNIQRGMVPRVFGRSYAIEARPHIPDGGAEGVIVANADFMG
MMAR_1232|M.marinum_M               TRFAFQGGVQNIQRGMVPRVFGRSYAIEARLHIPDGGAEGVIVANADFMG
Mb3327c|M.bovis_AF2122/97           ARFSFKGDVQNIQRGMVPRICGRSYAIEARLHIPDGGAQGVIVANADFMG
Rv3299c|M.tuberculosis_H37Rv        ARFSFKGDVQNIQRGMVPRICGRSYAIEARLHIPDGGAQGVIVANADFMG
Mvan_4467|M.vanbaalenii_PYR-1       TTQTLFSGMRLLEN-CVLNIKNRSHAVSALISVPDSGAQGVIVSQGGGVG
                                               :    .  : .:*. : *   :    *:**:. :.   *

Mflv_5039|M.gilvum_PYR-GCK          GYVMYLQGG-RLHFCYNFLGEYEQTLAAPDPVPPGLHTLGFTYTVTGTAE
MSMEG_1451|M.smegmatis_MC2_155      GHVLFIADG-HLHYVYNFLGEREQVLSAPDPVPLGHHIFGVRYERTGTVP
MAV_4461|M.avium_104                GHVLFIQDG-RLHYVYNFLGERQQEVSSSVPVPLGRHLFGASYARTGTVP
TH_0315|M.thermoresistible__bu      GYVLFLQDG-RLHFVYNFMGEEEQRVSSADPIPAGRHILGVSYHRTGTVD
MAB_4307|M.abscessus_ATCC_1997      GHVLFIKDG-RLHYVYNFLGIKPEQEFISAPLTPGNRTLGVEFVRRDKGQ
MUL_2658|M.ulcerans_Agy99           GFALWVDEQRRLHHTYSFLGIETYRQVSTEPVPTGDVTVRMLFESEAPV-
MMAR_1232|M.marinum_M               GFALWVDEQRRLHHTYSFLGIETYRQVSTEPVPTGDVTVRMLFESEAPV-
Mb3327c|M.bovis_AF2122/97           GFALWVDEQRHLHHTYSFLGVETYRQVSSEPLPTGDVTVRMLFDSHQPV-
Rv3299c|M.tuberculosis_H37Rv        GFALWVDEQRHLHHTYSFLGVETYRQVSSEPLPTGDVTVRMLFDSHQPV-
Mvan_4467|M.vanbaalenii_PYR-1       GWCVYAHEN-TLKYCYNFFGIEYYFVTAELPLPGGQHLVGFEFAYDGGG-
                                    *  ::      *:. *.*:*          *:. *   .   :       

Mflv_5039|M.gilvum_PYR-GCK          GSHTPIGDAELFLDTERVASLAEMRSQPGTFGLAGASLSVGRNNGSPVSE
MSMEG_1451|M.smegmatis_MC2_155      NSHTPVGVATLFVDGGAVADLADVQTHPAIFALAGGGIAVGRNTGSGVSR
MAV_4461|M.avium_104                DSHTPLGDLTLFIDDEVVGTLAGVSTHPGTFGLAGAGITVGRNGGSGVSS
TH_0315|M.thermoresistible__bu      GSHTPLGEVALYVDGTVVATRPDVRAHPANFGLAGGGIAVGRNTGQPVSS
MAB_4307|M.abscessus_ATCC_1997      YGES-LGTTNLYVDGKLAATGP-MRTQVGTFTLAGDGLCVGYDSGDNVSP
MUL_2658|M.ulcerans_Agy99           --VGSGGRVTLWANDRLIGEGELPQTVTLAFTSYAG-LDVGRDNGLVVDR
MMAR_1232|M.marinum_M               --IGSGGRVTLWANDRLIGEGELPQTVTLAFTSYAG-LDVGRDNGLVVDR
Mb3327c|M.bovis_AF2122/97           --AASGGRVTLWADDRLIGEGELPQTVPLAFTSYAG-MDIGRDNGLVVDR
Rv3299c|M.tuberculosis_H37Rv        --AASGGRVTLWADDRLIGEGELPQTVPLAFTSYAG-MDIGRDNGLVVDR
Mvan_4467|M.vanbaalenii_PYR-1       --LGKGGTVTLYCDGEPVGTGRVERTEPMAFSADEA-CDVGSDTGSPTSP
                                          *   *: :    .      :    *        :* : *  .. 

Mflv_5039|M.gilvum_PYR-GCK          AY--HPPFAFAGGRIARVNIDTS---GAPYVDLERDFARAFARD----
MSMEG_1451|M.smegmatis_MC2_155      SY--RVPFPFTGGEIAQVTVDLS---GEPYEDLVTRRATAFARD----
MAV_4461|M.avium_104                RF--KAPFVFTGGTIARVTLDLS---GRPYRDVETEIALAFSRD----
TH_0315|M.thermoresistible__bu      AY--RAPFAFTGGSIAKVIVDIS---GTPYRDVEREAAMAFARD----
MAB_4307|M.abscessus_ATCC_1997      QY--TNPGRFTGGTIKVVAVDVS---DESFIDLEKEAQAAFARD----
MUL_2658|M.ulcerans_Agy99           DYEDKALYMFSG-TVKEVVFDLKPVHPDAEKALHEHASIQAVGQGAAG
MMAR_1232|M.marinum_M               DYEDKAPYTFSG-TVKEVVFDLKPVHPDAEKALHEHASIQAVGQGAAG
Mb3327c|M.bovis_AF2122/97           GYEDKAPYAFTG-TVTEVIFDLKPVHPEAARALHEHASVQAVGQGAAG
Rv3299c|M.tuberculosis_H37Rv        GYEDKAPYAFTG-TVTEVIFDLKPVHPEAARALHEHASVQAVGQGAAG
Mvan_4467|M.vanbaalenii_PYR-1       DYGPHG-NGFNG-RIDWVKIDISTDDHEHLITPQDRFNISMARQ----
                                     :       * *  :  * .* .                    :