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PNGKPNILVIWGDDIGITNLSCYSDGLMGYRTPHIDRIANEGMRFTDAYGEQSCTAGRAAFISGQSVYRT GMSKVGMPGSDIGWSGQDPTIADLLKPLGYATGQFGKNHLGDRNKHLPTVHGFDEFFGNLYHLNAEEEPE LPDYPKSDRFPVLAELNRPRGVLRCWATEEVSDEPDDPKYGPVGKQRIVDTGPLTKQRMETIDDETTEAC VDFIKRQAAADTPFFVWMNMTHMHLRTHTKPESVGQAGVWQSPYHDTMIDHDRNVGQLLDALDELGIAQD TIVIYSTDNGPHANTWPDGATTPFRSEKNTNWEGAFRIPEMIRWPGKISAGVVSNEIIQHHDWLPTFLAA AGEPDIIEKLKKGHKISVRGDDKEFKVHLDAFNLLPYLTGEVEESPRQGFIYFSDDCDVLGIRFHNWKIV FQEQRCQGTLQVWAEPFVPLRVPKIFNLRTDPFERADITSNTYYDWFLDHDFIAFYGTAICTQFLETFKE FPPRHPPASFTIDQAVEKLQAIVKD*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_4410 | aslA | - | 100% (516) | arylsulfatase, AslA |
M. marinum M | MMAR_2840 | atsD_2 | 3e-14 | 25.07% (335) | arylsulfatase AtsD_2 |
M. marinum M | MMAR_4950 | atsD | 1e-13 | 25.15% (330) | arylsulfatase AtsD |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3327c | atsB | 2e-11 | 30.50% (141) | arylsulfatase AtsB |
M. gilvum PYR-GCK | Mflv_5039 | - | 3e-09 | 27.63% (152) | sulfatase |
M. tuberculosis H37Rv | Rv3299c | atsB | 2e-11 | 30.50% (141) | arylsulfatase AtsB |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_4307 | - | 3e-11 | 26.99% (163) | arylsulfatase AtsA |
M. avium 104 | MAV_2989 | - | 9e-18 | 23.42% (427) | arylsulfatase |
M. smegmatis MC2 155 | MSMEG_1228 | - | 4e-43 | 29.51% (471) | sulfatase |
M. thermoresistible (build 8) | TH_0315 | - | 3e-11 | 23.12% (320) | arylsulfatase |
M. ulcerans Agy99 | MUL_0227 | aslA | 0.0 | 98.45% (516) | arylsulfatase, AslA |
M. vanbaalenii PYR-1 | Mvan_4629 | - | 0.0 | 63.67% (512) | sulfatase |
CLUSTAL 2.0.9 multiple sequence alignment Mb3327c|M.bovis_AF2122/97 MMSEDNALVLVAGYQDLDSARHDFQTLVDAAKDKSIPLQGAVLIGKDAEG Rv3299c|M.tuberculosis_H37Rv MMSEDNALVLVAGYQDLDSARHDFQTLVDAAKDKSIPLQGAVLIGKDAEG Mflv_5039|M.gilvum_PYR-GCK -------------------------------------------------- TH_0315|M.thermoresistible__bu -------------------------------------------------- MAB_4307|M.abscessus_ATCC_1997 -----------------------------------------MHIPGDDAP MAV_2989|M.avium_104 -------------------------------------------------- MMAR_4410|M.marinum_M -------------------------------------------------- MUL_0227|M.ulcerans_Agy99 -------------------------------------------------- Mvan_4629|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_1228|M.smegmatis_MC2_155 -------------------------------------------------- Mb3327c|M.bovis_AF2122/97 SPVLVDTGNRLGRRGAAWGAGVGLAIGLFSPALLASAALGAATGALAGTF Rv3299c|M.tuberculosis_H37Rv SPVLVDTGNRLGRRGAAWGAGVGLAIGLFSPALLASAALGAATGALAGTF Mflv_5039|M.gilvum_PYR-GCK -------------------------------------------------- TH_0315|M.thermoresistible__bu -------------------------------------------------- MAB_4307|M.abscessus_ATCC_1997 EPEQNAERGRLTRR------------------------------------ MAV_2989|M.avium_104 -------------------------------------------------- MMAR_4410|M.marinum_M -------------------------------------------------- MUL_0227|M.ulcerans_Agy99 -------------------------------------------------- Mvan_4629|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_1228|M.smegmatis_MC2_155 -------------------------------------------------- Mb3327c|M.bovis_AF2122/97 AHHRIKTGLADKIGQALAAGRAVVIAVTEAQGRLEAGQALASSPMKSVAE Rv3299c|M.tuberculosis_H37Rv AHHRIKTGLADKIGQALAAGRAVVIAVTEAQGRLEAGQALASSPMKSVAE Mflv_5039|M.gilvum_PYR-GCK -------------------------------------------------- TH_0315|M.thermoresistible__bu -------------------------------------------------- MAB_4307|M.abscessus_ATCC_1997 ----------SMLGGIAAAGMGVAAASALVAG----------------CD MAV_2989|M.avium_104 -------------------------------------------------- MMAR_4410|M.marinum_M -------------------------------------------------- MUL_0227|M.ulcerans_Agy99 -------------------------------------------------- Mvan_4629|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_1228|M.smegmatis_MC2_155 -------------------------------------------------- Mb3327c|M.bovis_AF2122/97 LSRSTLRSLGAALREAMGKFNPDRTRLPLPQRRFGGVVGRTMAESVGDWS Rv3299c|M.tuberculosis_H37Rv LSRSTLRSLGAALREAMGKFNPDRTRLPLPQRRFGGVVGRTMAESVGDWS Mflv_5039|M.gilvum_PYR-GCK ---------------MTTEFN--------------GKIALDIRDSEPDWG TH_0315|M.thermoresistible__bu ----------------MADFG--------------GKIELDIRDSEPDWG MAB_4307|M.abscessus_ATCC_1997 DDSSSRTDRSSAAEEANAGFN--------------GKIELDVRDSKPDWT MAV_2989|M.avium_104 -------------------------------------------------- MMAR_4410|M.marinum_M -------------------------------------------------- MUL_0227|M.ulcerans_Agy99 -------------------------------------------------- Mvan_4629|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_1228|M.smegmatis_MC2_155 -------------------------------------------------- Mb3327c|M.bovis_AF2122/97 IVPSPFPPDDAPNVLIVLIDDAGFGGPDTFGG----AIRTPTLSRLAQNG Rv3299c|M.tuberculosis_H37Rv IVPGPFPPDDAPNVLIVLIDDAGFGGPDTFGG----AIRTPTLSRLAQNG Mflv_5039|M.gilvum_PYR-GCK PFAAPTAQPEAPNVLYLVWDDIGIATWDCFGG----LVDMPAMSRIAERG TH_0315|M.thermoresistible__bu PFAAPTAPEGAPNILYVVWDDVGIGTWDCFGG----LVEMPTMSRIAEQG MAB_4307|M.abscessus_ATCC_1997 PYELKHAPDGAPNVLVVLFDDTGMATWSPYGG----RVNMPTLQRLADNG MAV_2989|M.avium_104 --------MKRPNFLVIVADDLGFSDLGAFGG----EIETPNLDRLAYAG MMAR_4410|M.marinum_M ------MPNGKPNILVIWGDDIGITNLSCYSDGLM-GYRTPHIDRIANEG MUL_0227|M.ulcerans_Agy99 ------MSNGKPNILVIWGDDIGITNLSCYSDGLM-GYRTPHIDRIANEG Mvan_4629|M.vanbaalenii_PYR-1 ------MGD-KPNILIIWGDDIGQSNLSCYSDGLM-GYRTANIDRIAAEG MSMEG_1228|M.smegmatis_MC2_155 -------MPEKPNIVYFHVDNLGMGELGCYGGGILRGADTVRMDAFAAES **.: . *: * . :.. :. :* . Mb3327c|M.bovis_AF2122/97 LIYNRFHVTAVCSPTRAALLTGRNHHRVGFGSVCEFPG----PYPGYSAV Rv3299c|M.tuberculosis_H37Rv LIYNRFHVTAVCSPTRAALLTGRNHHRVGFGSVCEFPG----PYPGYSAV Mflv_5039|M.gilvum_PYR-GCK VRLSQFHTTALCSPTRASLLTGRNATTVGMATIEEFTD----GFPNCNGR TH_0315|M.thermoresistible__bu VRLSQFHTTALCSPTRAALLTGRNPTTVGMATIEEFTD----GFPNCSGR MAB_4307|M.abscessus_ATCC_1997 LTYSQWHTTALCSPTRSCLLTGRNHHVNRFASITEGSD----GYPGAAGR MAV_2989|M.avium_104 IRLTDFHSAPACSPTRAMLLTGTDHHIAGIGTMLEVAAPQFHGAPGYEGY MMAR_4410|M.marinum_M MRFTDAYGEQSCTAGRAAFISGQSVYRTGMSKVG---------MPGSDIG MUL_0227|M.ulcerans_Agy99 MRFTDAYGEQSCTAGRAAFISGQSVYRTGMSKVG---------MPDSDIG Mvan_4629|M.vanbaalenii_PYR-1 ARFTDYYGEQSCTAGRAAFITGQNPYRTGLTKVG---------MPGAPIG MSMEG_1228|M.smegmatis_MC2_155 LKLTHFVVEPQCTPTRSALMTGRYPIRSGNHTIA---------LGGNGGG . *:. *: :::* .: . Mb3327c|M.bovis_AF2122/97 RPRSCAALPRILRDNGYVTGAFGKWHLTPDNVQGAAGPFDNWPLGWGFDH Rv3299c|M.tuberculosis_H37Rv RPRSCAALPRILRDNGYVTGAFGKWHLTPDNVQGAAGPFDNWPLGWGFDH Mflv_5039|M.gilvum_PYR-GCK IPFDTALLSEVLSENGYNTYCIGKWHLTPLEESNLAATKRHWPLSRGFER TH_0315|M.thermoresistible__bu IPVDTGLISEVLAEHGWNTYCVGKWHLTPLEESNMAATKRHWPVSRGFER MAB_4307|M.abscessus_ATCC_1997 LPAQCATIGQVLQDNGYSTFWVGKNHNVPQEDVSCGGSKSEWPLQKGFDR MAV_2989|M.avium_104 LNDRVVALPELLRDAGYLTLMSGKWHLG--------ATIETSPWARGFER MMAR_4410|M.marinum_M WSGQDPTIADLLKPLGYATGQFGKNHLG--------DRNKHLPTVHGFDE MUL_0227|M.ulcerans_Agy99 WSGQDPTIADLLKPLGYATGQFGKNHLG--------DRNKHLPTVHGFDE Mvan_4629|M.vanbaalenii_PYR-1 LQAEDPTIATALKAQGYATGQFGKNHLG--------DRDEFLPTMHGFDE MSMEG_1228|M.smegmatis_MC2_155 IVSWERTMGDILSEAGYATACFGKWHIG--------AEDGRWPTDHGFDE : * *: * ** * * **:. Mb3327c|M.bovis_AF2122/97 FWGFPSGAAGQYDPIISQDNSVIGIPEGSGEDGR---PYYFPDDLTDKAI Rv3299c|M.tuberculosis_H37Rv FWGFPSGAAGQYDPIISQDNSVIGIPEGSGEDGR---PYYFPDDLTDKAI Mflv_5039|M.gilvum_PYR-GCK FYGFMGGETDQWYPDLMYDNHPVAPP-ATPEEG-----YHLSKDLADKTI TH_0315|M.thermoresistible__bu FYGFLGGETDQWYPDLVHDNHPVAPP-ATPEDG-----YHLSKDLADKTI MAB_4307|M.abscessus_ATCC_1997 YYGFLGGETNNWYPDLVEDNRFIEQP-TSPEQG-----YHLSKDLADQAL MAV_2989|M.avium_104 SFALLPAGASHYGGSGARGFSPVPTLYTEDDRFVSVGDDFYSSDSYTDTL MMAR_4410|M.marinum_M FFGNLYHLNAEEEPELPDYPKSDRFPVLAELNRP-----------RGVLR MUL_0227|M.ulcerans_Agy99 FFGNLCHLNAEEEPELPDYPKSDRFPVLAELNRP-----------RGVLR Mvan_4629|M.vanbaalenii_PYR-1 FFGNLYHLNAEEEPENVDYPKD---PEFRKKFGP-----------RGVIR MSMEG_1228|M.smegmatis_MC2_155 WYGPARTYDECLWPDDPWYDGERDGYSYMYEGTK---------------- :. Mb3327c|M.bovis_AF2122/97 EWLHTVRAQNATKPWMLYYATGATHAPHHVFKEWADKYRGEFDDGWDVYR Rv3299c|M.tuberculosis_H37Rv EWLHTVRAQNATKPWMLYYATGATHAPHHVFKEWADKYRGEFDDGWDVYR Mflv_5039|M.gilvum_PYR-GCK EFIRDSKVIAPDKPWFSYVCPGAGHAPHHVFKEWADRYAGRFDMGYEAYR TH_0315|M.thermoresistible__bu EFIRDAKVIAPDKPWFTYLCPGAGHAPHHAPRDWADRYAGRFDMGYERYR MAB_4307|M.abscessus_ATCC_1997 RMLRDQRNTNPSKPWYMWFCPGANHAPHHSPAEYADKYRGKFDDGYEAYR MAV_2989|M.avium_104 LRYLDERAPDDDRPFFAYLPFQAPHWPLQAPDESIAKYRGRYDEGPDVLR MMAR_4410|M.marinum_M CWATEEVSDEPDDPKYGPVGKQRIVDTGPLTKQRMETIDDETTEACVDFI MUL_0227|M.ulcerans_Agy99 CWATEEVSDEPDDPKYGPVGKQRIVDTGPLTKQRMETIDDETTEACVDFI Mvan_4629|M.vanbaalenii_PYR-1 AWANGD-------------GTQRIEDTGPLTRKRMETCDEEFRDAAIDFI MSMEG_1228|M.smegmatis_MC2_155 -------------------ADGVHATDQQLTVKLKGEMDGEYDRRAKAFM . . Mb3327c|M.bovis_AF2122/97 QKTFERQKRLGIIPPDAELTERP----------------DLFPAWDSMSE Rv3299c|M.tuberculosis_H37Rv QKTFERQKRLGIIPPDAELTERP----------------DLFPAWDSMSE Mflv_5039|M.gilvum_PYR-GCK EIVLENQKRLGLVPPDTELSAVNPYLDVKGPDGQDWPAQDTVRPWDSLSE TH_0315|M.thermoresistible__bu EVVLENQKKLGIVPPDTELPPINPYQDVKGPHGEPWPLQDTVRPWDSLSD MAB_4307|M.abscessus_ATCC_1997 EWVLARMIDKGIMPRETKLTPINPLPNDVAVEA------DSVRPWNTLNP MAV_2989|M.avium_104 AERLAALKRLGLCPPDVTPHPVVA---------------DGAPEWADMTD MMAR_4410|M.marinum_M KRQAAADTPFFVWMNMTHMHLRT-----------------------HTKP MUL_0227|M.ulcerans_Agy99 KRQAAADTPFFVWMNMTHMHLRT-----------------------HTKP Mvan_4629|M.vanbaalenii_PYR-1 KRQHEADTPFFVWFNSTHMHFRT-----------------------HPKP MSMEG_1228|M.smegmatis_MC2_155 KRSVEADKPFFLYHNHSLMHFPM-------------------------EV : Mb3327c|M.bovis_AF2122/97 AQKRLFARQMEVFAGFSENADWNVGRLLDAIEDLGESDNTLVFYIWGDNG Rv3299c|M.tuberculosis_H37Rv AQKRLFARQMEVFAGFSENADWNVGRLLDAIEDLGESDNTLVFYIWGDNG Mflv_5039|M.gilvum_PYR-GCK DEKRLFARMAEVFAGFLSYTDAQIGRVLDYLEESGQLDNTVIVVIS-DNG TH_0315|M.thermoresistible__bu AEKRLFCRMAEVFAGFLSYTDHQIGRVLDYLEESDQLDNTLIVVLS-DNG MAB_4307|M.abscessus_ATCC_1997 DEKRLFSRMAEVFAGFSEYTDAQVGRVIDYLEQTGQLDNTVVFYCA-DNG MAV_2989|M.avium_104 EERARSARTMEVYAGMVDRMDYNVGRVIDYLSRSGELDNTVVIFLS-DNG MMAR_4410|M.marinum_M ESVGQAGVWQSPYHDTMIDHDRNVGQLLDALDELGIAQDTIVIYST-DNG MUL_0227|M.ulcerans_Agy99 ESVGQAGVWQSPYHDTMIDHDRNVGQLLDALDELGIAQDTIVIYST-DNG Mvan_4629|M.vanbaalenii_PYR-1 ESIGRSGRWQSEYHDTMLDHDDIVGDLLNTLDELGIADGTIVMYST-DNG MSMEG_1228|M.smegmatis_MC2_155 REEFKGKSTNGQWGDSLLMLDYDFGSILDYLAELGIEDNTIVIMAG-DNG . : . * .* ::: : . :.*::. *** Mb3327c|M.bovis_AF2122/97 ASMEGTNTGSFNEMTFLNGLDLDAERQLELIEQYGGIAALGDEFTAPHFA Rv3299c|M.tuberculosis_H37Rv ASMEGTNTGSFNEMTFLNGLDLDAERQLELIEQYGGIAALGDEFTAPHFA Mflv_5039|M.gilvum_PYR-GCK ASGEGGPNGSVNEVKFFNGYIDSAEESLKVFDELGGPQTYN------HYP TH_0315|M.thermoresistible__bu ASGEGGPDGSVNEVKFFNGYVDTVEESMRFYDQLGGPQTYN------HYP MAB_4307|M.abscessus_ATCC_1997 ASGEGSPNGSVNENKFFNGYPDDLAENMKYIDRLGTPDTYN------HYP MAV_2989|M.avium_104 AEGAIVEAMPLRGPQIAAQIEKHCDNSLDNLGRPTSFIWYG--------- MMAR_4410|M.marinum_M PHAN---------------------------------------------- MUL_0227|M.ulcerans_Agy99 PHAN---------------------------------------------- Mvan_4629|M.vanbaalenii_PYR-1 PHMN---------------------------------------------- MSMEG_1228|M.smegmatis_MC2_155 AEDH---------------------------------------------- . Mb3327c|M.bovis_AF2122/97 SAWAHASNTPLQWGKQMASHLGGTRDPLVVAWPARIRPDGRVRSQFTHCI Rv3299c|M.tuberculosis_H37Rv SAWAHASNTPLQWGKQMASHLGGTRDPLVVAWPARIRPDGRVRSQFTHCI Mflv_5039|M.gilvum_PYR-GCK IGWAMAFNTPYKLFKRYASHEGGIADTAIISWPKGIAAHGEIRDNYVNVA TH_0315|M.thermoresistible__bu TGWAMAFNTPYKLFKRYASHEGGIADPAIISWPNGITARDAVCDRYINVV MAB_4307|M.abscessus_ATCC_1997 TGWAVAFSTPFQMFKRYSQFSGGTCDPLVIHWPKGIKAKGEVRHQYHHVT MAV_2989|M.avium_104 PRWAQAATAPSRLHKAFTTQGG-IRVPGFITWPG-FARQGQIGTAFSTVM MMAR_4410|M.marinum_M -TWPDGATTPFRS-EKNTNWEGAFRIPEMIRWPGKISAG-VVSNEIIQHH MUL_0227|M.ulcerans_Agy99 -TWPDGATTPFRS-EKNTNWEGALRIPEMIRWPGKISAG-VVSNEIIQHH Mvan_4629|M.vanbaalenii_PYR-1 -SWPDAGMTPFRN-EKNSNWEGAYRVPAVVRWPGRIPAG-TVLNGIVSHN MSMEG_1228|M.smegmatis_MC2_155 --LAGRGTAGFFDGSYFSSAEGGIRTPCLIRWPGKVVPR--ESNEMVHVT . : . : * . .: ** . Mb3327c|M.bovis_AF2122/97 DIAPTVLAAIGLPEP-THVDG-----------FEQEPMDGTSFVRTFD-- Rv3299c|M.tuberculosis_H37Rv DIAPTVLAAIGLPEP-THVDG-----------FEQEPMDGTSFVRTFD-- Mflv_5039|M.gilvum_PYR-GCK DITPTVYDLLDITPP-ATVRG-----------VAQKPLDGVSFKVALE-- TH_0315|M.thermoresistible__bu DVTPTVYELIGLTPP-DTVRG-----------VRQRPLEGVSFRAALA-- MAB_4307|M.abscessus_ATCC_1997 DIVPTILDVAGLTMP-ETYRG-----------VDQFPVNGVSMRYTFD-- MAV_2989|M.avium_104 DIAPTLLELAGTSHPGTAYRG-----------REVAPMRGRSLVGYLSGA MMAR_4410|M.marinum_M DWLPTFLAAAGEPDIIEKLKKGHKISVRGDDKEFKVHLDAFNLLPYLTGE MUL_0227|M.ulcerans_Agy99 DRLPTFLAAAGEPDIIEKLKKGHKISVRGDDKEFKVHLDAFNLLPYLTGE Mvan_4629|M.vanbaalenii_PYR-1 DWFVTLLAAAGDPDIAERLRAGTDLNG----TTYKVHLDGHNQLDYLTGA MSMEG_1228|M.smegmatis_MC2_155 DMFPTLLRWVGCDIP------------------DDRIIDGIDQREFFSG- * *. . : . . : Mb3327c|M.bovis_AF2122/97 DAEAEDRHTVQYFENFGSRAIYKDGWWACARLDKAPWDLSPETMRRFAPG Rv3299c|M.tuberculosis_H37Rv DAEAEDRHTVQYFENFGSRAIYKDGWWACARLDKAPWDLSPETMRRFAPG Mflv_5039|M.gilvum_PYR-GCK NPNAPTGKETQFYTMLGTRGIWHRGWFANTVHAASPAGWS---------- TH_0315|M.thermoresistible__bu DPDADTGKRTQFYSMLGTRGIWSDGWFANTVHAASPAGWS---------- MAB_4307|M.abscessus_ATCC_1997 DKDAATTKKRQYYAMLGTRGIWEDGWKASALHAP-ISGKG---------- MAV_2989|M.avium_104 ADTVHDADTETGWELFGRRAIRQGNWKALHLPAP---------------- MMAR_4410|M.marinum_M VEESPRQGFIYFSDDCDVLGIRFHNWKIVFQEQRCQG------------- MUL_0227|M.ulcerans_Agy99 VEESPRQGFIYFSDDCDVLGIRFHNWKIVFQEQRCQG------------- Mvan_4629|M.vanbaalenii_PYR-1 TDESPRQYFFYVSDDGDLTALRYDNWKIVFLEQRAAG------------- MSMEG_1228|M.smegmatis_MC2_155 -AEESNRDGCMVWLNEELHAVKWSQFKINFKRQQ---------------- .: : Mb3327c|M.bovis_AF2122/97 TYDPDQDVWELYYLPDDFSQAKNLAAEHPDKVAELTQLWWQEAERNRVLP Rv3299c|M.tuberculosis_H37Rv TYDPDQDVWELYYLPDDFSQAKNLAAEHPDKVAELTQLWWQEAERNRVLP Mflv_5039|M.gilvum_PYR-GCK --HFDDDRWELYHVDADRSQVHDLAAEYPEKLDELKALWFSEAQKYNGLP TH_0315|M.thermoresistible__bu --NFDADRWELYHLESDRSQSRDLAAEHPEKLEELKQLWFDEAAKYNGLP MAB_4307|M.abscessus_ATCC_1997 --HFDQDKWELFHVDEDRSESTDLADQHPDKLKALIDAWFEEADNNFVLP MAV_2989|M.avium_104 ---YGPGSWQLYDLASDPGEVDDLAAARPDKLAELLALWDRYVEET---- MMAR_4410|M.marinum_M ----TLQVWAEPFVPLRVPKIFNLRTDPFERADITSNTYYDWFLDH---- MUL_0227|M.ulcerans_Agy99 ----TLQVWAEPFIPLRVPKIFNLRTDPYERADITSNTYYDWFLDH---- Mvan_4629|M.vanbaalenii_PYR-1 ----TLQVWLEPYTELRAPKLFNLRTDPYERADITSNTYFDWVLDR---- MSMEG_1228|M.smegmatis_MC2_155 -------HFHDPEVPLGFARITNLLED-PKEREPVNQTWVR--------- : . :* .. : Mb3327c|M.bovis_AF2122/97 L--LGGLAVMFGDLPPLP-TTARFSFKGDVQNIQRGMVPRICGRSYAIEA Rv3299c|M.tuberculosis_H37Rv L--LGGLAVMFGDLPPLP-TTARFSFKGDVQNIQRGMVPRICGRSYAIEA Mflv_5039|M.gilvum_PYR-GCK LGDLDIFETMSRWRPTLSGERSAYVYYPGTADVGIGAVVELRGRSFAVLA TH_0315|M.thermoresistible__bu LGDLNLFETLGRWRPHLSRGRTSYTYYPGTAEVGLGAAVDIRGQSFTVLA MAB_4307|M.abscessus_ATCC_1997 LDDRLPTELLTIERPQFEPRRNRYLYYPDASPVPEGVAVNIRGKSYKIVA MAV_2989|M.avium_104 -------------------------------------------------- MMAR_4410|M.marinum_M -------------------------------------------------- MUL_0227|M.ulcerans_Agy99 -------------------------------------------------- Mvan_4629|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_1228|M.smegmatis_MC2_155 -------------------------------------------------- Mb3327c|M.bovis_AF2122/97 RLHIPDGGAQGVIVANADFMGGFALWVDEQRHLHHTYSFLGVETYRQVSS Rv3299c|M.tuberculosis_H37Rv RLHIPDGGAQGVIVANADFMGGFALWVDEQRHLHHTYSFLGVETYRQVSS Mflv_5039|M.gilvum_PYR-GCK EVEVDPGGANGVVVKHGGAHGGYVMYLQGGR-LHFCYNFLGEYEQTLAAP TH_0315|M.thermoresistible__bu DVTVDAAGAQGVIVKHGAGHGGYVLFLQDGR-LHFVYNFMGEEEQRVSSA MAB_4307|M.abscessus_ATCC_1997 NTDIS-AQAQGVIFAHGSRFGGHVLFIKDGR-LHYVYNFLGIKPEQEFIS MAV_2989|M.avium_104 ----------GVILDPISVFDAEL-------------------------- MMAR_4410|M.marinum_M ----------DFIAFYGTAICTQFLETFKEFPPRHPPASFTIDQAVEKLQ MUL_0227|M.ulcerans_Agy99 ----------DFIAFYGTAICTQFLETFKEFPPRHPPARFTIDQAVEKLQ Mvan_4629|M.vanbaalenii_PYR-1 ----------VFVFTPAQAFVAQMLQTLVEFPQRQASASFNLEQVMAKLQ MSMEG_1228|M.smegmatis_MC2_155 ----------WWVMQHAYRFIQEFEASVEKEQLIPAGAPLDFVPARNP-- : Mb3327c|M.bovis_AF2122/97 EPLPTGDVTVRMLFDSHQPVAASGG---RVTLWADDRLIGEGELPQTVPL Rv3299c|M.tuberculosis_H37Rv EPLPTGDVTVRMLFDSHQPVAASGG---RVTLWADDRLIGEGELPQTVPL Mflv_5039|M.gilvum_PYR-GCK DPVPPGLHTLGFTYTVTGTAEGSHTPIGDAELFLDTERVASLAEMRSQPG TH_0315|M.thermoresistible__bu DPIPAGRHILGVSYHRTGTVDGSHTPLGEVALYVDGTVVATRPDVRAHPA MAB_4307|M.abscessus_ATCC_1997 APLTPGNRTLGVEFVRRDKGQYGES-LGTTNLYVDGKLAATGP-MRTQVG MAV_2989|M.avium_104 -------------------------------------------------- MMAR_4410|M.marinum_M AIVKD--------------------------------------------- MUL_0227|M.ulcerans_Agy99 AIVKD--------------------------------------------- Mvan_4629|M.vanbaalenii_PYR-1 AGIPDS-------------------------------------------- MSMEG_1228|M.smegmatis_MC2_155 -------------------------------------------------- Mb3327c|M.bovis_AF2122/97 AFTSY-AGMDIGRDNGLVVDRGYEDKAPYAFTG-TVTEVIFDLKPVHPEA Rv3299c|M.tuberculosis_H37Rv AFTSY-AGMDIGRDNGLVVDRGYEDKAPYAFTG-TVTEVIFDLKPVHPEA Mflv_5039|M.gilvum_PYR-GCK TFGLAGASLSVGRNNGSPVSEAYHP--PFAFAGGRIARVNIDTS----GA TH_0315|M.thermoresistible__bu NFGLAGGGIAVGRNTGQPVSSAYRA--PFAFTGGSIAKVIVDIS----GT MAB_4307|M.abscessus_ATCC_1997 TFTLAGDGLCVGYDSGDNVSPQYTN--PGRFTGGTIKVVAVDVS----DE MAV_2989|M.avium_104 -------------------------------------------------- MMAR_4410|M.marinum_M -------------------------------------------------- MUL_0227|M.ulcerans_Agy99 -------------------------------------------------- Mvan_4629|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_1228|M.smegmatis_MC2_155 -------------------------------------------------- Mb3327c|M.bovis_AF2122/97 ARALHEHASVQAVGQGAAG Rv3299c|M.tuberculosis_H37Rv ARALHEHASVQAVGQGAAG Mflv_5039|M.gilvum_PYR-GCK PYVDLERDFARAFARD--- TH_0315|M.thermoresistible__bu PYRDVEREAAMAFARD--- MAB_4307|M.abscessus_ATCC_1997 SFIDLEKEAQAAFARD--- MAV_2989|M.avium_104 ------------------- MMAR_4410|M.marinum_M ------------------- MUL_0227|M.ulcerans_Agy99 ------------------- Mvan_4629|M.vanbaalenii_PYR-1 ------------------- MSMEG_1228|M.smegmatis_MC2_155 -------------------