For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. marinum M MMAR_4410 (aslA)

annotation: arylsulfatase, AslA
coordinates: 5423744 - 5425294
length: 516

PNGKPNILVIWGDDIGITNLSCYSDGLMGYRTPHIDRIANEGMRFTDAYGEQSCTAGRAAFISGQSVYRT
GMSKVGMPGSDIGWSGQDPTIADLLKPLGYATGQFGKNHLGDRNKHLPTVHGFDEFFGNLYHLNAEEEPE
LPDYPKSDRFPVLAELNRPRGVLRCWATEEVSDEPDDPKYGPVGKQRIVDTGPLTKQRMETIDDETTEAC
VDFIKRQAAADTPFFVWMNMTHMHLRTHTKPESVGQAGVWQSPYHDTMIDHDRNVGQLLDALDELGIAQD
TIVIYSTDNGPHANTWPDGATTPFRSEKNTNWEGAFRIPEMIRWPGKISAGVVSNEIIQHHDWLPTFLAA
AGEPDIIEKLKKGHKISVRGDDKEFKVHLDAFNLLPYLTGEVEESPRQGFIYFSDDCDVLGIRFHNWKIV
FQEQRCQGTLQVWAEPFVPLRVPKIFNLRTDPFERADITSNTYYDWFLDHDFIAFYGTAICTQFLETFKE
FPPRHPPASFTIDQAVEKLQAIVKD*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_4410aslA-100% (516)arylsulfatase, AslA
M. marinum MMMAR_2840atsD_23e-1425.07% (335) arylsulfatase AtsD_2
M. marinum MMMAR_4950atsD1e-1325.15% (330) arylsulfatase AtsD

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3327catsB2e-1130.50% (141) arylsulfatase AtsB
M. gilvum PYR-GCKMflv_5039-3e-0927.63% (152) sulfatase
M. tuberculosis H37RvRv3299catsB2e-1130.50% (141) arylsulfatase AtsB
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4307-3e-1126.99% (163) arylsulfatase AtsA
M. avium 104MAV_2989-9e-1823.42% (427) arylsulfatase
M. smegmatis MC2 155MSMEG_1228-4e-4329.51% (471) sulfatase
M. thermoresistible (build 8)TH_0315-3e-1123.12% (320) arylsulfatase
M. ulcerans Agy99MUL_0227aslA0.098.45% (516) arylsulfatase, AslA
M. vanbaalenii PYR-1Mvan_4629-0.063.67% (512) sulfatase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3327c|M.bovis_AF2122/97           MMSEDNALVLVAGYQDLDSARHDFQTLVDAAKDKSIPLQGAVLIGKDAEG
Rv3299c|M.tuberculosis_H37Rv        MMSEDNALVLVAGYQDLDSARHDFQTLVDAAKDKSIPLQGAVLIGKDAEG
Mflv_5039|M.gilvum_PYR-GCK          --------------------------------------------------
TH_0315|M.thermoresistible__bu      --------------------------------------------------
MAB_4307|M.abscessus_ATCC_1997      -----------------------------------------MHIPGDDAP
MAV_2989|M.avium_104                --------------------------------------------------
MMAR_4410|M.marinum_M               --------------------------------------------------
MUL_0227|M.ulcerans_Agy99           --------------------------------------------------
Mvan_4629|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1228|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3327c|M.bovis_AF2122/97           SPVLVDTGNRLGRRGAAWGAGVGLAIGLFSPALLASAALGAATGALAGTF
Rv3299c|M.tuberculosis_H37Rv        SPVLVDTGNRLGRRGAAWGAGVGLAIGLFSPALLASAALGAATGALAGTF
Mflv_5039|M.gilvum_PYR-GCK          --------------------------------------------------
TH_0315|M.thermoresistible__bu      --------------------------------------------------
MAB_4307|M.abscessus_ATCC_1997      EPEQNAERGRLTRR------------------------------------
MAV_2989|M.avium_104                --------------------------------------------------
MMAR_4410|M.marinum_M               --------------------------------------------------
MUL_0227|M.ulcerans_Agy99           --------------------------------------------------
Mvan_4629|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1228|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3327c|M.bovis_AF2122/97           AHHRIKTGLADKIGQALAAGRAVVIAVTEAQGRLEAGQALASSPMKSVAE
Rv3299c|M.tuberculosis_H37Rv        AHHRIKTGLADKIGQALAAGRAVVIAVTEAQGRLEAGQALASSPMKSVAE
Mflv_5039|M.gilvum_PYR-GCK          --------------------------------------------------
TH_0315|M.thermoresistible__bu      --------------------------------------------------
MAB_4307|M.abscessus_ATCC_1997      ----------SMLGGIAAAGMGVAAASALVAG----------------CD
MAV_2989|M.avium_104                --------------------------------------------------
MMAR_4410|M.marinum_M               --------------------------------------------------
MUL_0227|M.ulcerans_Agy99           --------------------------------------------------
Mvan_4629|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1228|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3327c|M.bovis_AF2122/97           LSRSTLRSLGAALREAMGKFNPDRTRLPLPQRRFGGVVGRTMAESVGDWS
Rv3299c|M.tuberculosis_H37Rv        LSRSTLRSLGAALREAMGKFNPDRTRLPLPQRRFGGVVGRTMAESVGDWS
Mflv_5039|M.gilvum_PYR-GCK          ---------------MTTEFN--------------GKIALDIRDSEPDWG
TH_0315|M.thermoresistible__bu      ----------------MADFG--------------GKIELDIRDSEPDWG
MAB_4307|M.abscessus_ATCC_1997      DDSSSRTDRSSAAEEANAGFN--------------GKIELDVRDSKPDWT
MAV_2989|M.avium_104                --------------------------------------------------
MMAR_4410|M.marinum_M               --------------------------------------------------
MUL_0227|M.ulcerans_Agy99           --------------------------------------------------
Mvan_4629|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1228|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3327c|M.bovis_AF2122/97           IVPSPFPPDDAPNVLIVLIDDAGFGGPDTFGG----AIRTPTLSRLAQNG
Rv3299c|M.tuberculosis_H37Rv        IVPGPFPPDDAPNVLIVLIDDAGFGGPDTFGG----AIRTPTLSRLAQNG
Mflv_5039|M.gilvum_PYR-GCK          PFAAPTAQPEAPNVLYLVWDDIGIATWDCFGG----LVDMPAMSRIAERG
TH_0315|M.thermoresistible__bu      PFAAPTAPEGAPNILYVVWDDVGIGTWDCFGG----LVEMPTMSRIAEQG
MAB_4307|M.abscessus_ATCC_1997      PYELKHAPDGAPNVLVVLFDDTGMATWSPYGG----RVNMPTLQRLADNG
MAV_2989|M.avium_104                --------MKRPNFLVIVADDLGFSDLGAFGG----EIETPNLDRLAYAG
MMAR_4410|M.marinum_M               ------MPNGKPNILVIWGDDIGITNLSCYSDGLM-GYRTPHIDRIANEG
MUL_0227|M.ulcerans_Agy99           ------MSNGKPNILVIWGDDIGITNLSCYSDGLM-GYRTPHIDRIANEG
Mvan_4629|M.vanbaalenii_PYR-1       ------MGD-KPNILIIWGDDIGQSNLSCYSDGLM-GYRTANIDRIAAEG
MSMEG_1228|M.smegmatis_MC2_155      -------MPEKPNIVYFHVDNLGMGELGCYGGGILRGADTVRMDAFAAES
                                               **.: .  *: *    . :..          :. :*  .

Mb3327c|M.bovis_AF2122/97           LIYNRFHVTAVCSPTRAALLTGRNHHRVGFGSVCEFPG----PYPGYSAV
Rv3299c|M.tuberculosis_H37Rv        LIYNRFHVTAVCSPTRAALLTGRNHHRVGFGSVCEFPG----PYPGYSAV
Mflv_5039|M.gilvum_PYR-GCK          VRLSQFHTTALCSPTRASLLTGRNATTVGMATIEEFTD----GFPNCNGR
TH_0315|M.thermoresistible__bu      VRLSQFHTTALCSPTRAALLTGRNPTTVGMATIEEFTD----GFPNCSGR
MAB_4307|M.abscessus_ATCC_1997      LTYSQWHTTALCSPTRSCLLTGRNHHVNRFASITEGSD----GYPGAAGR
MAV_2989|M.avium_104                IRLTDFHSAPACSPTRAMLLTGTDHHIAGIGTMLEVAAPQFHGAPGYEGY
MMAR_4410|M.marinum_M               MRFTDAYGEQSCTAGRAAFISGQSVYRTGMSKVG---------MPGSDIG
MUL_0227|M.ulcerans_Agy99           MRFTDAYGEQSCTAGRAAFISGQSVYRTGMSKVG---------MPDSDIG
Mvan_4629|M.vanbaalenii_PYR-1       ARFTDYYGEQSCTAGRAAFITGQNPYRTGLTKVG---------MPGAPIG
MSMEG_1228|M.smegmatis_MC2_155      LKLTHFVVEPQCTPTRSALMTGRYPIRSGNHTIA---------LGGNGGG
                                       .       *:. *: :::*         .:            .    

Mb3327c|M.bovis_AF2122/97           RPRSCAALPRILRDNGYVTGAFGKWHLTPDNVQGAAGPFDNWPLGWGFDH
Rv3299c|M.tuberculosis_H37Rv        RPRSCAALPRILRDNGYVTGAFGKWHLTPDNVQGAAGPFDNWPLGWGFDH
Mflv_5039|M.gilvum_PYR-GCK          IPFDTALLSEVLSENGYNTYCIGKWHLTPLEESNLAATKRHWPLSRGFER
TH_0315|M.thermoresistible__bu      IPVDTGLISEVLAEHGWNTYCVGKWHLTPLEESNMAATKRHWPVSRGFER
MAB_4307|M.abscessus_ATCC_1997      LPAQCATIGQVLQDNGYSTFWVGKNHNVPQEDVSCGGSKSEWPLQKGFDR
MAV_2989|M.avium_104                LNDRVVALPELLRDAGYLTLMSGKWHLG--------ATIETSPWARGFER
MMAR_4410|M.marinum_M               WSGQDPTIADLLKPLGYATGQFGKNHLG--------DRNKHLPTVHGFDE
MUL_0227|M.ulcerans_Agy99           WSGQDPTIADLLKPLGYATGQFGKNHLG--------DRNKHLPTVHGFDE
Mvan_4629|M.vanbaalenii_PYR-1       LQAEDPTIATALKAQGYATGQFGKNHLG--------DRDEFLPTMHGFDE
MSMEG_1228|M.smegmatis_MC2_155      IVSWERTMGDILSEAGYATACFGKWHIG--------AEDGRWPTDHGFDE
                                           :   *   *: *   ** *                *   **:.

Mb3327c|M.bovis_AF2122/97           FWGFPSGAAGQYDPIISQDNSVIGIPEGSGEDGR---PYYFPDDLTDKAI
Rv3299c|M.tuberculosis_H37Rv        FWGFPSGAAGQYDPIISQDNSVIGIPEGSGEDGR---PYYFPDDLTDKAI
Mflv_5039|M.gilvum_PYR-GCK          FYGFMGGETDQWYPDLMYDNHPVAPP-ATPEEG-----YHLSKDLADKTI
TH_0315|M.thermoresistible__bu      FYGFLGGETDQWYPDLVHDNHPVAPP-ATPEDG-----YHLSKDLADKTI
MAB_4307|M.abscessus_ATCC_1997      YYGFLGGETNNWYPDLVEDNRFIEQP-TSPEQG-----YHLSKDLADQAL
MAV_2989|M.avium_104                SFALLPAGASHYGGSGARGFSPVPTLYTEDDRFVSVGDDFYSSDSYTDTL
MMAR_4410|M.marinum_M               FFGNLYHLNAEEEPELPDYPKSDRFPVLAELNRP-----------RGVLR
MUL_0227|M.ulcerans_Agy99           FFGNLCHLNAEEEPELPDYPKSDRFPVLAELNRP-----------RGVLR
Mvan_4629|M.vanbaalenii_PYR-1       FFGNLYHLNAEEEPENVDYPKD---PEFRKKFGP-----------RGVIR
MSMEG_1228|M.smegmatis_MC2_155      WYGPARTYDECLWPDDPWYDGERDGYSYMYEGTK----------------
                                     :.                                               

Mb3327c|M.bovis_AF2122/97           EWLHTVRAQNATKPWMLYYATGATHAPHHVFKEWADKYRGEFDDGWDVYR
Rv3299c|M.tuberculosis_H37Rv        EWLHTVRAQNATKPWMLYYATGATHAPHHVFKEWADKYRGEFDDGWDVYR
Mflv_5039|M.gilvum_PYR-GCK          EFIRDSKVIAPDKPWFSYVCPGAGHAPHHVFKEWADRYAGRFDMGYEAYR
TH_0315|M.thermoresistible__bu      EFIRDAKVIAPDKPWFTYLCPGAGHAPHHAPRDWADRYAGRFDMGYERYR
MAB_4307|M.abscessus_ATCC_1997      RMLRDQRNTNPSKPWYMWFCPGANHAPHHSPAEYADKYRGKFDDGYEAYR
MAV_2989|M.avium_104                LRYLDERAPDDDRPFFAYLPFQAPHWPLQAPDESIAKYRGRYDEGPDVLR
MMAR_4410|M.marinum_M               CWATEEVSDEPDDPKYGPVGKQRIVDTGPLTKQRMETIDDETTEACVDFI
MUL_0227|M.ulcerans_Agy99           CWATEEVSDEPDDPKYGPVGKQRIVDTGPLTKQRMETIDDETTEACVDFI
Mvan_4629|M.vanbaalenii_PYR-1       AWANGD-------------GTQRIEDTGPLTRKRMETCDEEFRDAAIDFI
MSMEG_1228|M.smegmatis_MC2_155      -------------------ADGVHATDQQLTVKLKGEMDGEYDRRAKAFM
                                                                    .       .         

Mb3327c|M.bovis_AF2122/97           QKTFERQKRLGIIPPDAELTERP----------------DLFPAWDSMSE
Rv3299c|M.tuberculosis_H37Rv        QKTFERQKRLGIIPPDAELTERP----------------DLFPAWDSMSE
Mflv_5039|M.gilvum_PYR-GCK          EIVLENQKRLGLVPPDTELSAVNPYLDVKGPDGQDWPAQDTVRPWDSLSE
TH_0315|M.thermoresistible__bu      EVVLENQKKLGIVPPDTELPPINPYQDVKGPHGEPWPLQDTVRPWDSLSD
MAB_4307|M.abscessus_ATCC_1997      EWVLARMIDKGIMPRETKLTPINPLPNDVAVEA------DSVRPWNTLNP
MAV_2989|M.avium_104                AERLAALKRLGLCPPDVTPHPVVA---------------DGAPEWADMTD
MMAR_4410|M.marinum_M               KRQAAADTPFFVWMNMTHMHLRT-----------------------HTKP
MUL_0227|M.ulcerans_Agy99           KRQAAADTPFFVWMNMTHMHLRT-----------------------HTKP
Mvan_4629|M.vanbaalenii_PYR-1       KRQHEADTPFFVWFNSTHMHFRT-----------------------HPKP
MSMEG_1228|M.smegmatis_MC2_155      KRSVEADKPFFLYHNHSLMHFPM-------------------------EV
                                               :                                      

Mb3327c|M.bovis_AF2122/97           AQKRLFARQMEVFAGFSENADWNVGRLLDAIEDLGESDNTLVFYIWGDNG
Rv3299c|M.tuberculosis_H37Rv        AQKRLFARQMEVFAGFSENADWNVGRLLDAIEDLGESDNTLVFYIWGDNG
Mflv_5039|M.gilvum_PYR-GCK          DEKRLFARMAEVFAGFLSYTDAQIGRVLDYLEESGQLDNTVIVVIS-DNG
TH_0315|M.thermoresistible__bu      AEKRLFCRMAEVFAGFLSYTDHQIGRVLDYLEESDQLDNTLIVVLS-DNG
MAB_4307|M.abscessus_ATCC_1997      DEKRLFSRMAEVFAGFSEYTDAQVGRVIDYLEQTGQLDNTVVFYCA-DNG
MAV_2989|M.avium_104                EERARSARTMEVYAGMVDRMDYNVGRVIDYLSRSGELDNTVVIFLS-DNG
MMAR_4410|M.marinum_M               ESVGQAGVWQSPYHDTMIDHDRNVGQLLDALDELGIAQDTIVIYST-DNG
MUL_0227|M.ulcerans_Agy99           ESVGQAGVWQSPYHDTMIDHDRNVGQLLDALDELGIAQDTIVIYST-DNG
Mvan_4629|M.vanbaalenii_PYR-1       ESIGRSGRWQSEYHDTMLDHDDIVGDLLNTLDELGIADGTIVMYST-DNG
MSMEG_1228|M.smegmatis_MC2_155      REEFKGKSTNGQWGDSLLMLDYDFGSILDYLAELGIEDNTIVIMAG-DNG
                                     .          : .     *  .* ::: :   .  :.*::.    ***

Mb3327c|M.bovis_AF2122/97           ASMEGTNTGSFNEMTFLNGLDLDAERQLELIEQYGGIAALGDEFTAPHFA
Rv3299c|M.tuberculosis_H37Rv        ASMEGTNTGSFNEMTFLNGLDLDAERQLELIEQYGGIAALGDEFTAPHFA
Mflv_5039|M.gilvum_PYR-GCK          ASGEGGPNGSVNEVKFFNGYIDSAEESLKVFDELGGPQTYN------HYP
TH_0315|M.thermoresistible__bu      ASGEGGPDGSVNEVKFFNGYVDTVEESMRFYDQLGGPQTYN------HYP
MAB_4307|M.abscessus_ATCC_1997      ASGEGSPNGSVNENKFFNGYPDDLAENMKYIDRLGTPDTYN------HYP
MAV_2989|M.avium_104                AEGAIVEAMPLRGPQIAAQIEKHCDNSLDNLGRPTSFIWYG---------
MMAR_4410|M.marinum_M               PHAN----------------------------------------------
MUL_0227|M.ulcerans_Agy99           PHAN----------------------------------------------
Mvan_4629|M.vanbaalenii_PYR-1       PHMN----------------------------------------------
MSMEG_1228|M.smegmatis_MC2_155      AEDH----------------------------------------------
                                    .                                                 

Mb3327c|M.bovis_AF2122/97           SAWAHASNTPLQWGKQMASHLGGTRDPLVVAWPARIRPDGRVRSQFTHCI
Rv3299c|M.tuberculosis_H37Rv        SAWAHASNTPLQWGKQMASHLGGTRDPLVVAWPARIRPDGRVRSQFTHCI
Mflv_5039|M.gilvum_PYR-GCK          IGWAMAFNTPYKLFKRYASHEGGIADTAIISWPKGIAAHGEIRDNYVNVA
TH_0315|M.thermoresistible__bu      TGWAMAFNTPYKLFKRYASHEGGIADPAIISWPNGITARDAVCDRYINVV
MAB_4307|M.abscessus_ATCC_1997      TGWAVAFSTPFQMFKRYSQFSGGTCDPLVIHWPKGIKAKGEVRHQYHHVT
MAV_2989|M.avium_104                PRWAQAATAPSRLHKAFTTQGG-IRVPGFITWPG-FARQGQIGTAFSTVM
MMAR_4410|M.marinum_M               -TWPDGATTPFRS-EKNTNWEGAFRIPEMIRWPGKISAG-VVSNEIIQHH
MUL_0227|M.ulcerans_Agy99           -TWPDGATTPFRS-EKNTNWEGALRIPEMIRWPGKISAG-VVSNEIIQHH
Mvan_4629|M.vanbaalenii_PYR-1       -SWPDAGMTPFRN-EKNSNWEGAYRVPAVVRWPGRIPAG-TVLNGIVSHN
MSMEG_1228|M.smegmatis_MC2_155      --LAGRGTAGFFDGSYFSSAEGGIRTPCLIRWPGKVVPR--ESNEMVHVT
                                       .    :     .  :   *    . .: **  .              

Mb3327c|M.bovis_AF2122/97           DIAPTVLAAIGLPEP-THVDG-----------FEQEPMDGTSFVRTFD--
Rv3299c|M.tuberculosis_H37Rv        DIAPTVLAAIGLPEP-THVDG-----------FEQEPMDGTSFVRTFD--
Mflv_5039|M.gilvum_PYR-GCK          DITPTVYDLLDITPP-ATVRG-----------VAQKPLDGVSFKVALE--
TH_0315|M.thermoresistible__bu      DVTPTVYELIGLTPP-DTVRG-----------VRQRPLEGVSFRAALA--
MAB_4307|M.abscessus_ATCC_1997      DIVPTILDVAGLTMP-ETYRG-----------VDQFPVNGVSMRYTFD--
MAV_2989|M.avium_104                DIAPTLLELAGTSHPGTAYRG-----------REVAPMRGRSLVGYLSGA
MMAR_4410|M.marinum_M               DWLPTFLAAAGEPDIIEKLKKGHKISVRGDDKEFKVHLDAFNLLPYLTGE
MUL_0227|M.ulcerans_Agy99           DRLPTFLAAAGEPDIIEKLKKGHKISVRGDDKEFKVHLDAFNLLPYLTGE
Mvan_4629|M.vanbaalenii_PYR-1       DWFVTLLAAAGDPDIAERLRAGTDLNG----TTYKVHLDGHNQLDYLTGA
MSMEG_1228|M.smegmatis_MC2_155      DMFPTLLRWVGCDIP------------------DDRIIDGIDQREFFSG-
                                    *   *.    .                          : . .    :   

Mb3327c|M.bovis_AF2122/97           DAEAEDRHTVQYFENFGSRAIYKDGWWACARLDKAPWDLSPETMRRFAPG
Rv3299c|M.tuberculosis_H37Rv        DAEAEDRHTVQYFENFGSRAIYKDGWWACARLDKAPWDLSPETMRRFAPG
Mflv_5039|M.gilvum_PYR-GCK          NPNAPTGKETQFYTMLGTRGIWHRGWFANTVHAASPAGWS----------
TH_0315|M.thermoresistible__bu      DPDADTGKRTQFYSMLGTRGIWSDGWFANTVHAASPAGWS----------
MAB_4307|M.abscessus_ATCC_1997      DKDAATTKKRQYYAMLGTRGIWEDGWKASALHAP-ISGKG----------
MAV_2989|M.avium_104                ADTVHDADTETGWELFGRRAIRQGNWKALHLPAP----------------
MMAR_4410|M.marinum_M               VEESPRQGFIYFSDDCDVLGIRFHNWKIVFQEQRCQG-------------
MUL_0227|M.ulcerans_Agy99           VEESPRQGFIYFSDDCDVLGIRFHNWKIVFQEQRCQG-------------
Mvan_4629|M.vanbaalenii_PYR-1       TDESPRQYFFYVSDDGDLTALRYDNWKIVFLEQRAAG-------------
MSMEG_1228|M.smegmatis_MC2_155      -AEESNRDGCMVWLNEELHAVKWSQFKINFKRQQ----------------
                                                       .:    :                        

Mb3327c|M.bovis_AF2122/97           TYDPDQDVWELYYLPDDFSQAKNLAAEHPDKVAELTQLWWQEAERNRVLP
Rv3299c|M.tuberculosis_H37Rv        TYDPDQDVWELYYLPDDFSQAKNLAAEHPDKVAELTQLWWQEAERNRVLP
Mflv_5039|M.gilvum_PYR-GCK          --HFDDDRWELYHVDADRSQVHDLAAEYPEKLDELKALWFSEAQKYNGLP
TH_0315|M.thermoresistible__bu      --NFDADRWELYHLESDRSQSRDLAAEHPEKLEELKQLWFDEAAKYNGLP
MAB_4307|M.abscessus_ATCC_1997      --HFDQDKWELFHVDEDRSESTDLADQHPDKLKALIDAWFEEADNNFVLP
MAV_2989|M.avium_104                ---YGPGSWQLYDLASDPGEVDDLAAARPDKLAELLALWDRYVEET----
MMAR_4410|M.marinum_M               ----TLQVWAEPFVPLRVPKIFNLRTDPFERADITSNTYYDWFLDH----
MUL_0227|M.ulcerans_Agy99           ----TLQVWAEPFIPLRVPKIFNLRTDPYERADITSNTYYDWFLDH----
Mvan_4629|M.vanbaalenii_PYR-1       ----TLQVWLEPYTELRAPKLFNLRTDPYERADITSNTYFDWVLDR----
MSMEG_1228|M.smegmatis_MC2_155      -------HFHDPEVPLGFARITNLLED-PKEREPVNQTWVR---------
                                            :          .  :*     ..       :           

Mb3327c|M.bovis_AF2122/97           L--LGGLAVMFGDLPPLP-TTARFSFKGDVQNIQRGMVPRICGRSYAIEA
Rv3299c|M.tuberculosis_H37Rv        L--LGGLAVMFGDLPPLP-TTARFSFKGDVQNIQRGMVPRICGRSYAIEA
Mflv_5039|M.gilvum_PYR-GCK          LGDLDIFETMSRWRPTLSGERSAYVYYPGTADVGIGAVVELRGRSFAVLA
TH_0315|M.thermoresistible__bu      LGDLNLFETLGRWRPHLSRGRTSYTYYPGTAEVGLGAAVDIRGQSFTVLA
MAB_4307|M.abscessus_ATCC_1997      LDDRLPTELLTIERPQFEPRRNRYLYYPDASPVPEGVAVNIRGKSYKIVA
MAV_2989|M.avium_104                --------------------------------------------------
MMAR_4410|M.marinum_M               --------------------------------------------------
MUL_0227|M.ulcerans_Agy99           --------------------------------------------------
Mvan_4629|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1228|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3327c|M.bovis_AF2122/97           RLHIPDGGAQGVIVANADFMGGFALWVDEQRHLHHTYSFLGVETYRQVSS
Rv3299c|M.tuberculosis_H37Rv        RLHIPDGGAQGVIVANADFMGGFALWVDEQRHLHHTYSFLGVETYRQVSS
Mflv_5039|M.gilvum_PYR-GCK          EVEVDPGGANGVVVKHGGAHGGYVMYLQGGR-LHFCYNFLGEYEQTLAAP
TH_0315|M.thermoresistible__bu      DVTVDAAGAQGVIVKHGAGHGGYVLFLQDGR-LHFVYNFMGEEEQRVSSA
MAB_4307|M.abscessus_ATCC_1997      NTDIS-AQAQGVIFAHGSRFGGHVLFIKDGR-LHYVYNFLGIKPEQEFIS
MAV_2989|M.avium_104                ----------GVILDPISVFDAEL--------------------------
MMAR_4410|M.marinum_M               ----------DFIAFYGTAICTQFLETFKEFPPRHPPASFTIDQAVEKLQ
MUL_0227|M.ulcerans_Agy99           ----------DFIAFYGTAICTQFLETFKEFPPRHPPARFTIDQAVEKLQ
Mvan_4629|M.vanbaalenii_PYR-1       ----------VFVFTPAQAFVAQMLQTLVEFPQRQASASFNLEQVMAKLQ
MSMEG_1228|M.smegmatis_MC2_155      ----------WWVMQHAYRFIQEFEASVEKEQLIPAGAPLDFVPARNP--
                                                :                                     

Mb3327c|M.bovis_AF2122/97           EPLPTGDVTVRMLFDSHQPVAASGG---RVTLWADDRLIGEGELPQTVPL
Rv3299c|M.tuberculosis_H37Rv        EPLPTGDVTVRMLFDSHQPVAASGG---RVTLWADDRLIGEGELPQTVPL
Mflv_5039|M.gilvum_PYR-GCK          DPVPPGLHTLGFTYTVTGTAEGSHTPIGDAELFLDTERVASLAEMRSQPG
TH_0315|M.thermoresistible__bu      DPIPAGRHILGVSYHRTGTVDGSHTPLGEVALYVDGTVVATRPDVRAHPA
MAB_4307|M.abscessus_ATCC_1997      APLTPGNRTLGVEFVRRDKGQYGES-LGTTNLYVDGKLAATGP-MRTQVG
MAV_2989|M.avium_104                --------------------------------------------------
MMAR_4410|M.marinum_M               AIVKD---------------------------------------------
MUL_0227|M.ulcerans_Agy99           AIVKD---------------------------------------------
Mvan_4629|M.vanbaalenii_PYR-1       AGIPDS--------------------------------------------
MSMEG_1228|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3327c|M.bovis_AF2122/97           AFTSY-AGMDIGRDNGLVVDRGYEDKAPYAFTG-TVTEVIFDLKPVHPEA
Rv3299c|M.tuberculosis_H37Rv        AFTSY-AGMDIGRDNGLVVDRGYEDKAPYAFTG-TVTEVIFDLKPVHPEA
Mflv_5039|M.gilvum_PYR-GCK          TFGLAGASLSVGRNNGSPVSEAYHP--PFAFAGGRIARVNIDTS----GA
TH_0315|M.thermoresistible__bu      NFGLAGGGIAVGRNTGQPVSSAYRA--PFAFTGGSIAKVIVDIS----GT
MAB_4307|M.abscessus_ATCC_1997      TFTLAGDGLCVGYDSGDNVSPQYTN--PGRFTGGTIKVVAVDVS----DE
MAV_2989|M.avium_104                --------------------------------------------------
MMAR_4410|M.marinum_M               --------------------------------------------------
MUL_0227|M.ulcerans_Agy99           --------------------------------------------------
Mvan_4629|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1228|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3327c|M.bovis_AF2122/97           ARALHEHASVQAVGQGAAG
Rv3299c|M.tuberculosis_H37Rv        ARALHEHASVQAVGQGAAG
Mflv_5039|M.gilvum_PYR-GCK          PYVDLERDFARAFARD---
TH_0315|M.thermoresistible__bu      PYRDVEREAAMAFARD---
MAB_4307|M.abscessus_ATCC_1997      SFIDLEKEAQAAFARD---
MAV_2989|M.avium_104                -------------------
MMAR_4410|M.marinum_M               -------------------
MUL_0227|M.ulcerans_Agy99           -------------------
Mvan_4629|M.vanbaalenii_PYR-1       -------------------
MSMEG_1228|M.smegmatis_MC2_155      -------------------