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KRPNFLVIVADDLGFSDLGAFGGEIETPNLDRLAYAGIRLTDFHSAPACSPTRAMLLTGTDHHIAGIGTM LEVAAPQFHGAPGYEGYLNDRVVALPELLRDAGYLTLMSGKWHLGATIETSPWARGFERSFALLPAGASH YGGSGARGFSPVPTLYTEDDRFVSVGDDFYSSDSYTDTLLRYLDERAPDDDRPFFAYLPFQAPHWPLQAP DESIAKYRGRYDEGPDVLRAERLAALKRLGLCPPDVTPHPVVADGAPEWADMTDEERARSARTMEVYAGM VDRMDYNVGRVIDYLSRSGELDNTVVIFLSDNGAEGAIVEAMPLRGPQIAAQIEKHCDNSLDNLGRPTSF IWYGPRWAQAATAPSRLHKAFTTQGGIRVPGFITWPGFARQGQIGTAFSTVMDIAPTLLELAGTSHPGTA YRGREVAPMRGRSLVGYLSGAADTVHDADTETGWELFGRRAIRQGNWKALHLPAPYGPGSWQLYDLASDP GEVDDLAAARPDKLAELLALWDRYVEETGVILDPISVFDAEL*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_2989 | - | - | 100% (533) | arylsulfatase |
M. avium 104 | MAV_4461 | - | 6e-65 | 32.06% (549) | arylsulfatase |
M. avium 104 | MAV_4858 | - | 1e-08 | 25.62% (324) | sulfatase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3327c | atsB | 1e-70 | 34.33% (571) | arylsulfatase AtsB |
M. gilvum PYR-GCK | Mflv_5039 | - | 2e-65 | 32.22% (568) | sulfatase |
M. tuberculosis H37Rv | Rv3299c | atsB | 1e-70 | 34.33% (571) | arylsulfatase AtsB |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_4307 | - | 6e-65 | 32.30% (551) | arylsulfatase AtsA |
M. marinum M | MMAR_1232 | atsB | 3e-70 | 34.19% (582) | arylsulfatase AtsB (aryl-sulfate sulphohydrolase) |
M. smegmatis MC2 155 | MSMEG_1451 | - | 7e-71 | 32.52% (575) | arylsulfatase |
M. thermoresistible (build 8) | TH_0315 | - | 7e-69 | 31.64% (572) | arylsulfatase |
M. ulcerans Agy99 | MUL_2658 | atsB | 7e-70 | 34.19% (582) | arylsulfatase AtsB (aryl-sulfate sulphohydrolase) |
M. vanbaalenii PYR-1 | Mvan_4467 | - | 9e-66 | 33.02% (536) | sulfatase |
CLUSTAL 2.0.9 multiple sequence alignment Mb3327c|M.bovis_AF2122/97 MMSEDNALVLVAGYQDLDSARHDFQTLVDAAKDKSIPLQGAVLIGKDAEG Rv3299c|M.tuberculosis_H37Rv MMSEDNALVLVAGYQDLDSARHDFQTLVDAAKDKSIPLQGAVLIGKDAEG MMAR_1232|M.marinum_M -MSEENTLVIVAGYQDLDAAQHDFENLTGRANAKTLPLQGAVLVGKDNEG MUL_2658|M.ulcerans_Agy99 -MSEENTLVIVAGYQDLDAAQHDFENLTGRANAKTLPLQGAVLVGKDNEG Mvan_4467|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_5039|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_1451|M.smegmatis_MC2_155 -------------------------------------------------- TH_0315|M.thermoresistible__bu -------------------------------------------------- MAB_4307|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_2989|M.avium_104 -------------------------------------------------- Mb3327c|M.bovis_AF2122/97 SPVLVDTGNRLGRRGAAWGAGVGLAIGLFSPALLASAALGAATGALAGTF Rv3299c|M.tuberculosis_H37Rv SPVLVDTGNRLGRRGAAWGAGVGLAIGLFSPALLASAALGAATGALAGTF MMAR_1232|M.marinum_M NPVLIDTGNRLGRRGAAWGAGAGLAVGLFSPALLASTAVGAAAGALAGTF MUL_2658|M.ulcerans_Agy99 NPVLIDTGNRLGRRGAAWGAGAGLAVGLVSPALLASTAVGAAAGALAGTF Mvan_4467|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_5039|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_1451|M.smegmatis_MC2_155 -------------------------------------------------- TH_0315|M.thermoresistible__bu -------------------------------------------------- MAB_4307|M.abscessus_ATCC_1997 -------------MHIPGDDAPEPEQNAERGRLTRRSMLGGIAAAGMGVA MAV_2989|M.avium_104 -------------------------------------------------- Mb3327c|M.bovis_AF2122/97 AHHRIKTGLADKIGQALAAGRAVVIAVTEAQGRLEAGQALASSPMKSVAE Rv3299c|M.tuberculosis_H37Rv AHHRIKTGLADKIGQALAAGRAVVIAVTEAQGRLEAGQALASSPMKSVAE MMAR_1232|M.marinum_M IQHRVKSGLADKIGQALSAGSAVVIAVTPAQGRLPVEQTLSGSPMKSVAE MUL_2658|M.ulcerans_Agy99 IQHRVKSGLADKIGQALSAGSAVVIAVTPAQGRLPVEQTLSGSPMKSVAE Mvan_4467|M.vanbaalenii_PYR-1 -------------------MRRDILPIPDPQ------------------- Mflv_5039|M.gilvum_PYR-GCK -------------------------MTTEFNG------------------ MSMEG_1451|M.smegmatis_MC2_155 -------------------------MAAEFNG------------------ TH_0315|M.thermoresistible__bu --------------------------MADFGG------------------ MAB_4307|M.abscessus_ATCC_1997 AASALVAGCDDDSSSRTDRSSAAEEANAGFNG------------------ MAV_2989|M.avium_104 -------------------------------------------------- Mb3327c|M.bovis_AF2122/97 LSRSTLRSLGAALREAMGKFNPDRTRLPLPQRRFGGVVGRTMAESVGDWS Rv3299c|M.tuberculosis_H37Rv LSRSTLRSLGAALREAMGKFNPDRTRLPLPQRRFGGVVGRTMAESVGDWS MMAR_1232|M.marinum_M LSRSTMRSLGAALQEAMGKFNPDRTKLPIPQRSFGGTIGRTMAESVGDWT MUL_2658|M.ulcerans_Agy99 LSRSTMRSLGAALQEAMGKFNPDRTKLPIPQR----TIGRTMAESVGDWT Mvan_4467|M.vanbaalenii_PYR-1 -------HVGLTTYDAK---DPDTTYPPITPLR----------------- Mflv_5039|M.gilvum_PYR-GCK -------KIALDIRDSE----PDWGPFAAPT------------------- MSMEG_1451|M.smegmatis_MC2_155 -------KIELDIRDSE----PDWGPFAAPT------------------- TH_0315|M.thermoresistible__bu -------KIELDIRDSE----PDWGPFAAPT------------------- MAB_4307|M.abscessus_ATCC_1997 -------KIELDVRDSK----PDWTPYELKH------------------- MAV_2989|M.avium_104 -------------------------------------------------- Mb3327c|M.bovis_AF2122/97 IVPSPFPPDDAPNVLIVLIDDAGFGGPDTFGGAIRTPTLSRLAQNGLIYN Rv3299c|M.tuberculosis_H37Rv IVPGPFPPDDAPNVLIVLIDDAGFGGPDTFGGAIRTPTLSRLAQNGLIYN MMAR_1232|M.marinum_M IVAGANAPDDAPNLLIVLIDDAGFGGPDTFGGGIRTPTLSRVANNGLAYN MUL_2658|M.ulcerans_Agy99 IVAGANAPDDAPNVLIVLIDDAGFGGPDTFGGGIRTPTLSRVANNGLAYN Mvan_4467|M.vanbaalenii_PYR-1 ------PPQGAPNVLIVLLDDVGFGASSAFGGPCATPTAERLAANGLKLN Mflv_5039|M.gilvum_PYR-GCK ------AQPEAPNVLYLVWDDIGIATWDCFGGLVDMPAMSRIAERGVRLS MSMEG_1451|M.smegmatis_MC2_155 ------AAEGAPNVLYVVWDDIGIATWDCFGGLVEMPAMSRIAEHGVRLS TH_0315|M.thermoresistible__bu ------APEGAPNILYVVWDDVGIGTWDCFGGLVEMPTMSRIAEQGVRLS MAB_4307|M.abscessus_ATCC_1997 ------APDGAPNVLVVLFDDTGMATWSPYGGRVNMPTLQRLADNGLTYS MAV_2989|M.avium_104 --------MKRPNFLVIVADDLGFSDLGAFGGEIETPNLDRLAYAGIRLT **.* :: ** *:. . :** * .*:* *: . Mb3327c|M.bovis_AF2122/97 RFHVTAVCSPTRAALLTGRNHHRVGFGSVCEFPG----PYPGYSAVRPRS Rv3299c|M.tuberculosis_H37Rv RFHVTAVCSPTRAALLTGRNHHRVGFGSVCEFPG----PYPGYSAVRPRS MMAR_1232|M.marinum_M RFHLTAICSPTRAALLTGRNHHRVGFGSVCELPG----PYPGYSTVKPRS MUL_2658|M.ulcerans_Agy99 RFHLTAICSPTRAALLTGRNHHRVGFGSVCELPG----PYPGYSTVKPRS Mvan_4467|M.vanbaalenii_PYR-1 RFHTTALCSPTRQALLTGRNHHSVGMGGVTEIAT----SAPGYSSIRPKD Mflv_5039|M.gilvum_PYR-GCK QFHTTALCSPTRASLLTGRNATTVGMATIEEFTD----GFPNCNGRIPFD MSMEG_1451|M.smegmatis_MC2_155 QFHTTALCSPTRAALLTGRNPTTVGMATIEEFTD----GFPNCSGRIPFE TH_0315|M.thermoresistible__bu QFHTTALCSPTRAALLTGRNPTTVGMATIEEFTD----GFPNCSGRIPVD MAB_4307|M.abscessus_ATCC_1997 QWHTTALCSPTRSCLLTGRNHHVNRFASITEGSD----GYPGAAGRLPAQ MAV_2989|M.avium_104 DFHSAPACSPTRAMLLTGTDHHIAGIGTMLEVAAPQFHGAPGYEGYLNDR :* :. ***** **** : :. : * . *. Mb3327c|M.bovis_AF2122/97 CAALPRILRDNGYVTGAFGKWHLTPDNVQGAAGPFDNWPLGWGFDHFWGF Rv3299c|M.tuberculosis_H37Rv CAALPRILRDNGYVTGAFGKWHLTPDNVQGAAGPFDNWPLGWGFDHFWGF MMAR_1232|M.marinum_M CAALPRILRDNGYVTGAFGKWHLTPDNVQGAAGPFDNWPLGWGFDHFWGF MUL_2658|M.ulcerans_Agy99 CAALPRILRDNGYVTGAFGKWHLTPDNVQGAAGPFDNWPLGWGFDHFWGF Mvan_4467|M.vanbaalenii_PYR-1 KAPVAETLRLNGYSTSQFGKCHEVPVWEVSPVGPFGQWPTGSGFEHFYGF Mflv_5039|M.gilvum_PYR-GCK TALLSEVLSENGYNTYCIGKWHLTPLEESNLAATKRHWPLSRGFERFYGF MSMEG_1451|M.smegmatis_MC2_155 TALLPEVLAENGYNTYCIGKWHLTPLEESNLASTKRHWPCSRGFERFYGF TH_0315|M.thermoresistible__bu TGLISEVLAEHGWNTYCVGKWHLTPLEESNMAATKRHWPVSRGFERFYGF MAB_4307|M.abscessus_ATCC_1997 CATIGQVLQDNGYSTFWVGKNHNVPQEDVSCGGSKSEWPLQKGFDRYYGF MAV_2989|M.avium_104 VVALPELLRDAGYLTLMSGKWHLG--------ATIETSPWARGFERSFAL : . * *: * ** * .. * **:: :.: Mb3327c|M.bovis_AF2122/97 PSGAAGQYDPIISQDNSVIGIPEGSG---EDGRPYYFPDDLTDKAIEWLH Rv3299c|M.tuberculosis_H37Rv PSGAAGQYDPIISQDNSVIGIPEGSG---EDGRPYYFPDDLTDKAIEWLH MMAR_1232|M.marinum_M PSGAAGQYDPIITQDNSVLGIPQG-----DDGKPYFFPDDLTDKAIEWLH MUL_2658|M.ulcerans_Agy99 PSGAAGQYDPIITQDNSVLGIPQG-----DDGKPYFFPDDLTDKAIEWLH Mvan_4467|M.vanbaalenii_PYR-1 IGGEANQYYPGLYEGTKPVEPEKT------PEQGYTLTEDLADRAITWVR Mflv_5039|M.gilvum_PYR-GCK MGGETDQWYPDLMYDNHPVAPPAT------PEEGYHLSKDLADKTIEFIR MSMEG_1451|M.smegmatis_MC2_155 MGGETDQWYPDLTYDNHPVDPPAT------PEEGYHLSKDLADKTIEFIR TH_0315|M.thermoresistible__bu LGGETDQWYPDLVHDNHPVAPPAT------PEDGYHLSKDLADKTIEFIR MAB_4307|M.abscessus_ATCC_1997 LGGETNNWYPDLVEDNRFIEQPTS------PEQGYHLSKDLADQALRMLR MAV_2989|M.avium_104 LPAGASHYGGSGARGFSPVPTLYTEDDRFVSVGDDFYSSDSYTDTLLRYL . :.:: . : ..* :: Mb3327c|M.bovis_AF2122/97 TVRAQNATKPWMLYYATGATHAPHHVFKEWADKYRGEFDDGWDVYRQKTF Rv3299c|M.tuberculosis_H37Rv TVRAQNATKPWMLYYATGATHAPHHVFKEWADKYRGEFDDGWDVYRQKTF MMAR_1232|M.marinum_M TVRAQNATKPWLLYYSTGATHAPHHVFKEWADKYQGQFDEGWDVYRQKTF MUL_2658|M.ulcerans_Agy99 TVRAQNATKPWLLYYSTGATHAPHHVFKEWADKYQGQFDEGWDVYRQKTF Mvan_4467|M.vanbaalenii_PYR-1 QQQALTPDKPFFMYFAPGATHAPHHVPKQWSDKYRGKFDDGWDVLRESML Mflv_5039|M.gilvum_PYR-GCK DSKVIAPDKPWFSYVCPGAGHAPHHVFKEWADRYAGRFDMGYEAYREIVL MSMEG_1451|M.smegmatis_MC2_155 DAKVVASDKPWFTYLCPGAGHAPHHVFKEWADRYKGRFDMGYERYREIVL TH_0315|M.thermoresistible__bu DAKVIAPDKPWFTYLCPGAGHAPHHAPRDWADRYAGRFDMGYERYREVVL MAB_4307|M.abscessus_ATCC_1997 DQRNTNPSKPWYMWFCPGANHAPHHSPAEYADKYRGKFDDGYEAYREWVL MAV_2989|M.avium_104 DERAPDDDRPFFAYLPFQAPHWPLQAPDESIAKYRGRYDEGPDVLRAERL : :*: : * * * : : :* *.:* * : * : Mb3327c|M.bovis_AF2122/97 ERQKRLGIIPPDAELTERP----------------DLFPAWDSMSEAQKR Rv3299c|M.tuberculosis_H37Rv ERQKRLGIIPPDAELTERP----------------DLFPAWDSMSEAQKR MMAR_1232|M.marinum_M ERQKELGIIPPDAELTERP----------------DLFPAWDSLSEAQQK MUL_2658|M.ulcerans_Agy99 ERQKELGIIPPDAELTERP----------------DLFPAWDSLSEAQQK Mvan_4467|M.vanbaalenii_PYR-1 DNQKALGVVPEDAQLTARH----------------DEIPAWDDMPDVLKP Mflv_5039|M.gilvum_PYR-GCK ENQKRLGLVPPDTELSAVNPYLDVKGPDGQDWPAQDTVRPWDSLSEDEKR MSMEG_1451|M.smegmatis_MC2_155 ENQKRMGLVPPDTELSPVNPYSEVTGPDGQPWPAQDTVRPWDSLSDDEKA TH_0315|M.thermoresistible__bu ENQKKLGIVPPDTELPPINPYQDVKGPHGEPWPLQDTVRPWDSLSDAEKR MAB_4307|M.abscessus_ATCC_1997 ARMIDKGIMPRETKLTPINPLPNDVAVEA------DSVRPWNTLNPDEKR MAV_2989|M.avium_104 AALKRLGLCPPDVTPHPVVA---------------DGAPEWADMTDEERA *: * :. * * : : Mb3327c|M.bovis_AF2122/97 LFARQMEVFAGFSENADWNVGRLLDAIEDLGESDNTLVFYIWGDNGASME Rv3299c|M.tuberculosis_H37Rv LFARQMEVFAGFSENADWNVGRLLDAIEDLGESDNTLVFYIWGDNGASME MMAR_1232|M.marinum_M LFARQMEVFAGFSENADWNVGRLLDAIDGLGESDNTLVFYIWGDNGASME MUL_2658|M.ulcerans_Agy99 LFARQMEVFAGFSENADWNVGRLLDAIDGLGESDNTLVFYIWGDNGASME Mvan_4467|M.vanbaalenii_PYR-1 VLARQMEIYAGFLEQTDHEIGRLVDAIDDLGALDNTLIYYIIGDNGASAE Mflv_5039|M.gilvum_PYR-GCK LFARMAEVFAGFLSYTDAQIGRVLDYLEESGQLDNTVIVVIS-DNGASGE MSMEG_1451|M.smegmatis_MC2_155 LFCRMAEVFAGFLSYTDAQIGRVLDYLEESGQIDNTIIVVIS-DNGASGE TH_0315|M.thermoresistible__bu LFCRMAEVFAGFLSYTDHQIGRVLDYLEESDQLDNTLIVVLS-DNGASGE MAB_4307|M.abscessus_ATCC_1997 LFSRMAEVFAGFSEYTDAQVGRVIDYLEQTGQLDNTVVFYCA-DNGASGE MAV_2989|M.avium_104 RSARTMEVYAGMVDRMDYNVGRVIDYLSRSGELDNTVVIFLS-DNGAEG- .* *::**: . * ::**::* :. . ***:: ****. Mb3327c|M.bovis_AF2122/97 GTNTGSFNEMTFLNGLD--LDAERQLELIEQYGGIAALGDEFTAPHFASA Rv3299c|M.tuberculosis_H37Rv GTNTGSFNEMTFLNGLD--LDAERQLELIEQYGGIAALGDEFTAPHFASA MMAR_1232|M.marinum_M GTNTGSFNEMTFLNGLD--LDAERQLELIEQYGGIEALGDEFTAPHFASA MUL_2658|M.ulcerans_Agy99 GTNTGSFNEMTFLNGLD--LDAERQLELIEQYGGIEALGDEFTAPHFASA Mvan_4467|M.vanbaalenii_PYR-1 GTPNGCFNEMCTLNGLAGIETPEFLLSKIDDFGTPDAYN------HYAVG Mflv_5039|M.gilvum_PYR-GCK GGPNGSVNEVKFFNGYI--DSAEESLKVFDELGGPQTYN------HYPIG MSMEG_1451|M.smegmatis_MC2_155 GGPNGSVNETKFFNGYI--DTAEEGLKFIDKLGGPQTYN------HYPIG TH_0315|M.thermoresistible__bu GGPDGSVNEVKFFNGYV--DTVEESMRFYDQLGGPQTYN------HYPTG MAB_4307|M.abscessus_ATCC_1997 GSPNGSVNENKFFNGYP--DDLAENMKYIDRLGTPDTYN------HYPTG MAV_2989|M.avium_104 ----AIVEAMPLRGPQIAAQIEKHCDNSLDNLGRPTSFI------WYGPR . .: . : * : : Mb3327c|M.bovis_AF2122/97 WAHASNTPLQWGKQMASHLGGTRDPLVVAWPARIRPDGRVRSQFTHCIDI Rv3299c|M.tuberculosis_H37Rv WAHASNTPLQWGKQMASHLGGTRDPLVVAWPARIRPDGRVRSQFTHCIDI MMAR_1232|M.marinum_M WAHANNTPFQWGKQMASHLGGTRDPMVVCWPSRIPREGGIRSQFTHCIDI MUL_2658|M.ulcerans_Agy99 WAHANNTPFQWGKQMASHLGGTRDPMVACWPSRIPREGGIRSQFTHCIDI Mvan_4467|M.vanbaalenii_PYR-1 WAHALCGPYQWTKQVASHWGGTRNGTIVHWPNGIAAKGETRNQFHHVIDV Mflv_5039|M.gilvum_PYR-GCK WAMAFNTPYKLFKRYASHEGGIADTAIISWPKGIAAHGEIRDNYVNVADI MSMEG_1451|M.smegmatis_MC2_155 WAMAFNTPYKLFKRYASHEGGIADPAIISWPKGIAARGEVRDNYVNVCDV TH_0315|M.thermoresistible__bu WAMAFNTPYKLFKRYASHEGGIADPAIISWPNGITARDAVCDRYINVVDV MAB_4307|M.abscessus_ATCC_1997 WAVAFSTPFQMFKRYSQFSGGTCDPLVIHWPKGIKAKGEVRHQYHHVTDI MAV_2989|M.avium_104 WAQAATAPSRLHKAFTTQGG-IRVPGFITWPG-FARQGQIGTAFSTVMDI ** * * : * : * . ** : . : *: Mb3327c|M.bovis_AF2122/97 APTVLAAIGLPEP-THVDGFEQEPMDGTSFVRTFD--DAEAEDRHTVQYF Rv3299c|M.tuberculosis_H37Rv APTVLAAIGLPEP-THVDGFEQEPMDGTSFVRTFD--DAEAEDRHTVQYF MMAR_1232|M.marinum_M APTVLQAIGLPEP-TSVDGFEQEPMDGTSFVHTFD--DAQAEERHTVQYF MUL_2658|M.ulcerans_Agy99 APTVLQAIGLPEP-TSVDGFEQEPMDGTSFVHTFD--DAQAEERHTVQYF Mvan_4467|M.vanbaalenii_PYR-1 VPTILEAAKLPAP-TVVNSIQQAPLEGVSMMSTLR--DRDADETHTVQYF Mflv_5039|M.gilvum_PYR-GCK TPTVYDLLDITPP-ATVRGVAQKPLDGVSFKVALE--NPNAPTGKETQFY MSMEG_1451|M.smegmatis_MC2_155 TPTVYDMLGITPP-ATVRGVPQKPLDGVSFKAALA--DPDAPTGKETQFY TH_0315|M.thermoresistible__bu TPTVYELIGLTPP-DTVRGVRQRPLEGVSFRAALA--DPDADTGKRTQFY MAB_4307|M.abscessus_ATCC_1997 VPTILDVAGLTMP-ETYRGVDQFPVNGVSMRYTFD--DKDAATTKKRQYY MAV_2989|M.avium_104 APTLLELAGTSHPGTAYRGREVAPMRGRSLVGYLSGAADTVHDADTETGW .**: . * . *: * *: : . . : Mb3327c|M.bovis_AF2122/97 ENFGSRAIYKDGWWACARLDKAPWDLSPETMRRFAPGTYDPDQDVWELYY Rv3299c|M.tuberculosis_H37Rv ENFGSRAIYKDGWWACARLDKAPWDLSPETMRRFAPGTYDPDQDVWELYY MMAR_1232|M.marinum_M ENFGSRSIYQDGWWACARLDKAPWDLSPQTMARFSPGNYDPEKDVWELYY MUL_2658|M.ulcerans_Agy99 ENFGSRSIYQDGWWACARLDKAPWDLSPQTMARFSPGNYDPEKDVWELYY Mvan_4467|M.vanbaalenii_PYR-1 EMFGNRGIYHKGWTAVT-KHRTPWIADQPPL----------DEDVWELY- Mflv_5039|M.gilvum_PYR-GCK TMLGTRGIWHRGWFANTVHAASPAGWS------------HFDDDRWELYH MSMEG_1451|M.smegmatis_MC2_155 AMLGTRGIWHKGWFANTVHAATPSGWG------------HFADDRWELFH TH_0315|M.thermoresistible__bu SMLGTRGIWSDGWFANTVHAASPAGWS------------NFDADRWELYH MAB_4307|M.abscessus_ATCC_1997 AMLGTRGIWEDGWKASALHAP-ISGKG------------HFDQDKWELFH MAV_2989|M.avium_104 ELFGRRAIRQGNWKALHLPAP-------------------YGPGSWQLYD :* *.* .* * . *:*: Mb3327c|M.bovis_AF2122/97 LPDDFSQAKNLAAEHPDKVAELTQLWWQEAERNRVLPLLGGLAVMFG--- Rv3299c|M.tuberculosis_H37Rv LPDDFSQAKNLAAEHPDKVAELTQLWWQEAERNRVLPLLGGLAVMFG--- MMAR_1232|M.marinum_M LPDDFSQARNVAAEHPDKLAELRELWWQEAERNRVLPLLGGLAVMYG--- MUL_2658|M.ulcerans_Agy99 LPDDFSQARNVAAEHPDKLAELRELWWQEAERNRVLPLLGGLAVMYG--- Mvan_4467|M.vanbaalenii_PYR-1 APDDWTQAHDLAAEQPERLAALQRLWLIEAVKYNVVPLDDRSFERFNPDI Mflv_5039|M.gilvum_PYR-GCK VDADRSQVHDLAAEYPEKLDELKALWFSEAQKYNGLPLGDLDIFETMS-- MSMEG_1451|M.smegmatis_MC2_155 IDADRSQCHDLAAEHPDRLEELKALWFSEADKYNGLPLGDLSILETTT-- TH_0315|M.thermoresistible__bu LESDRSQSRDLAAEHPEKLEELKQLWFDEAAKYNGLPLGDLNLFETLG-- MAB_4307|M.abscessus_ATCC_1997 VDEDRSESTDLADQHPDKLKALIDAWFEEADNNFVLPLDDRLPTELLT-- MAV_2989|M.avium_104 LASDPGEVDDLAAARPDKLAELLALWDRYVEETGVILDPISVFDAEL--- * : ::* *::: * * . . : Mb3327c|M.bovis_AF2122/97 -DLPPLP-TTARFSFKGDVQNIQRGMVPRICGRSYAIEARLHIPDGGAQG Rv3299c|M.tuberculosis_H37Rv -DLPPLP-TTARFSFKGDVQNIQRGMVPRICGRSYAIEARLHIPDGGAQG MMAR_1232|M.marinum_M -ELPPLP-TTTRFAFQGGVQNIQRGMVPRVFGRSYAIEARLHIPDGGAEG MUL_2658|M.ulcerans_Agy99 -ELPPLP-TITRFAFQGGVQNIQRGMVPRVFGRSYAIEARPHIPDGGAEG Mvan_4467|M.vanbaalenii_PYR-1 AGRPQLI-KGTTQTLFSGMRLLEN-CVLNIKNRSHAVSALISVPDSGAQG Mflv_5039|M.gilvum_PYR-GCK RWRPTLSGERSAYVYYPGTADVGIGAVVELRGRSFAVLAEVEVDPGGANG MSMEG_1451|M.smegmatis_MC2_155 RWRPYLTGERTSYTYYPHTAEVGMGAVVELRGQSFKVLAEVTVDSAEAQG TH_0315|M.thermoresistible__bu RWRPHLSRGRTSYTYYPGTAEVGLGAAVDIRGQSFTVLADVTVDAAGAQG MAB_4307|M.abscessus_ATCC_1997 IERPQFEPRRNRYLYYPDASPVPEGVAVNIRGKSYKIVANTDIS-AQAQG MAV_2989|M.avium_104 -------------------------------------------------- Mb3327c|M.bovis_AF2122/97 VIVANADFMGGFALWVDEQRHLHHTYSFLGVETYRQVSSEPLPTGDVTVR Rv3299c|M.tuberculosis_H37Rv VIVANADFMGGFALWVDEQRHLHHTYSFLGVETYRQVSSEPLPTGDVTVR MMAR_1232|M.marinum_M VIVANADFMGGFALWVDEQRRLHHTYSFLGIETYRQVSTEPVPTGDVTVR MUL_2658|M.ulcerans_Agy99 VIVANADFMGGFALWVDEQRRLHHTYSFLGIETYRQVSTEPVPTGDVTVR Mvan_4467|M.vanbaalenii_PYR-1 VIVSQGGGVGGWCVYAHEN-TLKYCYNFFGIEYYFVTAELPLPGGQHLVG Mflv_5039|M.gilvum_PYR-GCK VVVKHGGAHGGYVMYLQGG-RLHFCYNFLGEYEQTLAAPDPVPPGLHTLG MSMEG_1451|M.smegmatis_MC2_155 VIFKHGGAHGGHVLFIADG-HLHYVYNFLGEREQVLSAPDPVPLGHHIFG TH_0315|M.thermoresistible__bu VIVKHGAGHGGYVLFLQDG-RLHFVYNFMGEEEQRVSSADPIPAGRHILG MAB_4307|M.abscessus_ATCC_1997 VIFAHGSRFGGHVLFIKDG-RLHYVYNFLGIKPEQEFISAPLTPGNRTLG MAV_2989|M.avium_104 -------------------------------------------------- Mb3327c|M.bovis_AF2122/97 MLFDSHQPV---AASGGRVTLWADDRLIGEGELPQTVPLAFTSYAG-MDI Rv3299c|M.tuberculosis_H37Rv MLFDSHQPV---AASGGRVTLWADDRLIGEGELPQTVPLAFTSYAG-MDI MMAR_1232|M.marinum_M MLFESEAPV---IGSGGRVTLWANDRLIGEGELPQTVTLAFTSYAG-LDV MUL_2658|M.ulcerans_Agy99 MLFESEAPV---VGSGGRVTLWANDRLIGEGELPQTVTLAFTSYAG-LDV Mvan_4467|M.vanbaalenii_PYR-1 FEFAYDGGG---LGKGGTVTLYCDGEPVGTGRVERTEPMAFSADEA-CDV Mflv_5039|M.gilvum_PYR-GCK FTYTVTGTAEGSHTPIGDAELFLDTERVASLAEMRSQPGTFGLAGASLSV MSMEG_1451|M.smegmatis_MC2_155 VRYERTGTVPNSHTPVGVATLFVDGGAVADLADVQTHPAIFALAGGGIAV TH_0315|M.thermoresistible__bu VSYHRTGTVDGSHTPLGEVALYVDGTVVATRPDVRAHPANFGLAGGGIAV MAB_4307|M.abscessus_ATCC_1997 VEFVRRDKGQYGES-LGTTNLYVDG-KLAATGPMRTQVGTFTLAGDGLCV MAV_2989|M.avium_104 -------------------------------------------------- Mb3327c|M.bovis_AF2122/97 GRDNGLVVDRGYEDKAPYAFTG-TVTEVIFDLKPVHPEAARALHEHASVQ Rv3299c|M.tuberculosis_H37Rv GRDNGLVVDRGYEDKAPYAFTG-TVTEVIFDLKPVHPEAARALHEHASVQ MMAR_1232|M.marinum_M GRDNGLVVDRDYEDKAPYTFSG-TVKEVVFDLKPVHPDAEKALHEHASIQ MUL_2658|M.ulcerans_Agy99 GRDNGLVVDRDYEDKALYMFSG-TVKEVVFDLKPVHPDAEKALHEHASIQ Mvan_4467|M.vanbaalenii_PYR-1 GSDTGSPTSPDYGPHG-NGFNG-RIDWVKIDISTDDHEHLITPQDRFNIS Mflv_5039|M.gilvum_PYR-GCK GRNNGSPVSEAYHPPF--AFAGGRIARVNIDTS---GAPYVDLERDFARA MSMEG_1451|M.smegmatis_MC2_155 GRNTGSGVSRSYRVPF--PFTGGEIAQVTVDLS---GEPYEDLVTRRATA TH_0315|M.thermoresistible__bu GRNTGQPVSSAYRAPF--AFTGGSIAKVIVDIS---GTPYRDVEREAAMA MAB_4307|M.abscessus_ATCC_1997 GYDSGDNVSPQYTNPG--RFTGGTIKVVAVDVS---DESFIDLEKEAQAA MAV_2989|M.avium_104 -------------------------------------------------- Mb3327c|M.bovis_AF2122/97 AVGQGAAG Rv3299c|M.tuberculosis_H37Rv AVGQGAAG MMAR_1232|M.marinum_M AVGQGAAG MUL_2658|M.ulcerans_Agy99 AVGQGAAG Mvan_4467|M.vanbaalenii_PYR-1 MARQ---- Mflv_5039|M.gilvum_PYR-GCK FARD---- MSMEG_1451|M.smegmatis_MC2_155 FARD---- TH_0315|M.thermoresistible__bu FARD---- MAB_4307|M.abscessus_ATCC_1997 FARD---- MAV_2989|M.avium_104 --------