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M. avium 104 MAV_2989 (-)

annotation: arylsulfatase
coordinates: 3025550 - 3027151
length: 533

KRPNFLVIVADDLGFSDLGAFGGEIETPNLDRLAYAGIRLTDFHSAPACSPTRAMLLTGTDHHIAGIGTM
LEVAAPQFHGAPGYEGYLNDRVVALPELLRDAGYLTLMSGKWHLGATIETSPWARGFERSFALLPAGASH
YGGSGARGFSPVPTLYTEDDRFVSVGDDFYSSDSYTDTLLRYLDERAPDDDRPFFAYLPFQAPHWPLQAP
DESIAKYRGRYDEGPDVLRAERLAALKRLGLCPPDVTPHPVVADGAPEWADMTDEERARSARTMEVYAGM
VDRMDYNVGRVIDYLSRSGELDNTVVIFLSDNGAEGAIVEAMPLRGPQIAAQIEKHCDNSLDNLGRPTSF
IWYGPRWAQAATAPSRLHKAFTTQGGIRVPGFITWPGFARQGQIGTAFSTVMDIAPTLLELAGTSHPGTA
YRGREVAPMRGRSLVGYLSGAADTVHDADTETGWELFGRRAIRQGNWKALHLPAPYGPGSWQLYDLASDP
GEVDDLAAARPDKLAELLALWDRYVEETGVILDPISVFDAEL*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_2989--100% (533)arylsulfatase
M. avium 104MAV_4461-6e-6532.06% (549) arylsulfatase
M. avium 104MAV_4858-1e-0825.62% (324) sulfatase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3327catsB1e-7034.33% (571) arylsulfatase AtsB
M. gilvum PYR-GCKMflv_5039-2e-6532.22% (568) sulfatase
M. tuberculosis H37RvRv3299catsB1e-7034.33% (571) arylsulfatase AtsB
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4307-6e-6532.30% (551) arylsulfatase AtsA
M. marinum MMMAR_1232atsB3e-7034.19% (582) arylsulfatase AtsB (aryl-sulfate sulphohydrolase)
M. smegmatis MC2 155MSMEG_1451-7e-7132.52% (575) arylsulfatase
M. thermoresistible (build 8)TH_0315-7e-6931.64% (572) arylsulfatase
M. ulcerans Agy99MUL_2658atsB7e-7034.19% (582) arylsulfatase AtsB (aryl-sulfate sulphohydrolase)
M. vanbaalenii PYR-1Mvan_4467-9e-6633.02% (536) sulfatase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3327c|M.bovis_AF2122/97           MMSEDNALVLVAGYQDLDSARHDFQTLVDAAKDKSIPLQGAVLIGKDAEG
Rv3299c|M.tuberculosis_H37Rv        MMSEDNALVLVAGYQDLDSARHDFQTLVDAAKDKSIPLQGAVLIGKDAEG
MMAR_1232|M.marinum_M               -MSEENTLVIVAGYQDLDAAQHDFENLTGRANAKTLPLQGAVLVGKDNEG
MUL_2658|M.ulcerans_Agy99           -MSEENTLVIVAGYQDLDAAQHDFENLTGRANAKTLPLQGAVLVGKDNEG
Mvan_4467|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5039|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_1451|M.smegmatis_MC2_155      --------------------------------------------------
TH_0315|M.thermoresistible__bu      --------------------------------------------------
MAB_4307|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_2989|M.avium_104                --------------------------------------------------
                                                                                      

Mb3327c|M.bovis_AF2122/97           SPVLVDTGNRLGRRGAAWGAGVGLAIGLFSPALLASAALGAATGALAGTF
Rv3299c|M.tuberculosis_H37Rv        SPVLVDTGNRLGRRGAAWGAGVGLAIGLFSPALLASAALGAATGALAGTF
MMAR_1232|M.marinum_M               NPVLIDTGNRLGRRGAAWGAGAGLAVGLFSPALLASTAVGAAAGALAGTF
MUL_2658|M.ulcerans_Agy99           NPVLIDTGNRLGRRGAAWGAGAGLAVGLVSPALLASTAVGAAAGALAGTF
Mvan_4467|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5039|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_1451|M.smegmatis_MC2_155      --------------------------------------------------
TH_0315|M.thermoresistible__bu      --------------------------------------------------
MAB_4307|M.abscessus_ATCC_1997      -------------MHIPGDDAPEPEQNAERGRLTRRSMLGGIAAAGMGVA
MAV_2989|M.avium_104                --------------------------------------------------
                                                                                      

Mb3327c|M.bovis_AF2122/97           AHHRIKTGLADKIGQALAAGRAVVIAVTEAQGRLEAGQALASSPMKSVAE
Rv3299c|M.tuberculosis_H37Rv        AHHRIKTGLADKIGQALAAGRAVVIAVTEAQGRLEAGQALASSPMKSVAE
MMAR_1232|M.marinum_M               IQHRVKSGLADKIGQALSAGSAVVIAVTPAQGRLPVEQTLSGSPMKSVAE
MUL_2658|M.ulcerans_Agy99           IQHRVKSGLADKIGQALSAGSAVVIAVTPAQGRLPVEQTLSGSPMKSVAE
Mvan_4467|M.vanbaalenii_PYR-1       -------------------MRRDILPIPDPQ-------------------
Mflv_5039|M.gilvum_PYR-GCK          -------------------------MTTEFNG------------------
MSMEG_1451|M.smegmatis_MC2_155      -------------------------MAAEFNG------------------
TH_0315|M.thermoresistible__bu      --------------------------MADFGG------------------
MAB_4307|M.abscessus_ATCC_1997      AASALVAGCDDDSSSRTDRSSAAEEANAGFNG------------------
MAV_2989|M.avium_104                --------------------------------------------------
                                                                                      

Mb3327c|M.bovis_AF2122/97           LSRSTLRSLGAALREAMGKFNPDRTRLPLPQRRFGGVVGRTMAESVGDWS
Rv3299c|M.tuberculosis_H37Rv        LSRSTLRSLGAALREAMGKFNPDRTRLPLPQRRFGGVVGRTMAESVGDWS
MMAR_1232|M.marinum_M               LSRSTMRSLGAALQEAMGKFNPDRTKLPIPQRSFGGTIGRTMAESVGDWT
MUL_2658|M.ulcerans_Agy99           LSRSTMRSLGAALQEAMGKFNPDRTKLPIPQR----TIGRTMAESVGDWT
Mvan_4467|M.vanbaalenii_PYR-1       -------HVGLTTYDAK---DPDTTYPPITPLR-----------------
Mflv_5039|M.gilvum_PYR-GCK          -------KIALDIRDSE----PDWGPFAAPT-------------------
MSMEG_1451|M.smegmatis_MC2_155      -------KIELDIRDSE----PDWGPFAAPT-------------------
TH_0315|M.thermoresistible__bu      -------KIELDIRDSE----PDWGPFAAPT-------------------
MAB_4307|M.abscessus_ATCC_1997      -------KIELDVRDSK----PDWTPYELKH-------------------
MAV_2989|M.avium_104                --------------------------------------------------
                                                                                      

Mb3327c|M.bovis_AF2122/97           IVPSPFPPDDAPNVLIVLIDDAGFGGPDTFGGAIRTPTLSRLAQNGLIYN
Rv3299c|M.tuberculosis_H37Rv        IVPGPFPPDDAPNVLIVLIDDAGFGGPDTFGGAIRTPTLSRLAQNGLIYN
MMAR_1232|M.marinum_M               IVAGANAPDDAPNLLIVLIDDAGFGGPDTFGGGIRTPTLSRVANNGLAYN
MUL_2658|M.ulcerans_Agy99           IVAGANAPDDAPNVLIVLIDDAGFGGPDTFGGGIRTPTLSRVANNGLAYN
Mvan_4467|M.vanbaalenii_PYR-1       ------PPQGAPNVLIVLLDDVGFGASSAFGGPCATPTAERLAANGLKLN
Mflv_5039|M.gilvum_PYR-GCK          ------AQPEAPNVLYLVWDDIGIATWDCFGGLVDMPAMSRIAERGVRLS
MSMEG_1451|M.smegmatis_MC2_155      ------AAEGAPNVLYVVWDDIGIATWDCFGGLVEMPAMSRIAEHGVRLS
TH_0315|M.thermoresistible__bu      ------APEGAPNILYVVWDDVGIGTWDCFGGLVEMPTMSRIAEQGVRLS
MAB_4307|M.abscessus_ATCC_1997      ------APDGAPNVLVVLFDDTGMATWSPYGGRVNMPTLQRLADNGLTYS
MAV_2989|M.avium_104                --------MKRPNFLVIVADDLGFSDLGAFGGEIETPNLDRLAYAGIRLT
                                               **.* :: ** *:.  . :**    *  .*:*  *:  .

Mb3327c|M.bovis_AF2122/97           RFHVTAVCSPTRAALLTGRNHHRVGFGSVCEFPG----PYPGYSAVRPRS
Rv3299c|M.tuberculosis_H37Rv        RFHVTAVCSPTRAALLTGRNHHRVGFGSVCEFPG----PYPGYSAVRPRS
MMAR_1232|M.marinum_M               RFHLTAICSPTRAALLTGRNHHRVGFGSVCELPG----PYPGYSTVKPRS
MUL_2658|M.ulcerans_Agy99           RFHLTAICSPTRAALLTGRNHHRVGFGSVCELPG----PYPGYSTVKPRS
Mvan_4467|M.vanbaalenii_PYR-1       RFHTTALCSPTRQALLTGRNHHSVGMGGVTEIAT----SAPGYSSIRPKD
Mflv_5039|M.gilvum_PYR-GCK          QFHTTALCSPTRASLLTGRNATTVGMATIEEFTD----GFPNCNGRIPFD
MSMEG_1451|M.smegmatis_MC2_155      QFHTTALCSPTRAALLTGRNPTTVGMATIEEFTD----GFPNCSGRIPFE
TH_0315|M.thermoresistible__bu      QFHTTALCSPTRAALLTGRNPTTVGMATIEEFTD----GFPNCSGRIPVD
MAB_4307|M.abscessus_ATCC_1997      QWHTTALCSPTRSCLLTGRNHHVNRFASITEGSD----GYPGAAGRLPAQ
MAV_2989|M.avium_104                DFHSAPACSPTRAMLLTGTDHHIAGIGTMLEVAAPQFHGAPGYEGYLNDR
                                     :* :. *****  **** :     :. : * .       *.        

Mb3327c|M.bovis_AF2122/97           CAALPRILRDNGYVTGAFGKWHLTPDNVQGAAGPFDNWPLGWGFDHFWGF
Rv3299c|M.tuberculosis_H37Rv        CAALPRILRDNGYVTGAFGKWHLTPDNVQGAAGPFDNWPLGWGFDHFWGF
MMAR_1232|M.marinum_M               CAALPRILRDNGYVTGAFGKWHLTPDNVQGAAGPFDNWPLGWGFDHFWGF
MUL_2658|M.ulcerans_Agy99           CAALPRILRDNGYVTGAFGKWHLTPDNVQGAAGPFDNWPLGWGFDHFWGF
Mvan_4467|M.vanbaalenii_PYR-1       KAPVAETLRLNGYSTSQFGKCHEVPVWEVSPVGPFGQWPTGSGFEHFYGF
Mflv_5039|M.gilvum_PYR-GCK          TALLSEVLSENGYNTYCIGKWHLTPLEESNLAATKRHWPLSRGFERFYGF
MSMEG_1451|M.smegmatis_MC2_155      TALLPEVLAENGYNTYCIGKWHLTPLEESNLASTKRHWPCSRGFERFYGF
TH_0315|M.thermoresistible__bu      TGLISEVLAEHGWNTYCVGKWHLTPLEESNMAATKRHWPVSRGFERFYGF
MAB_4307|M.abscessus_ATCC_1997      CATIGQVLQDNGYSTFWVGKNHNVPQEDVSCGGSKSEWPLQKGFDRYYGF
MAV_2989|M.avium_104                VVALPELLRDAGYLTLMSGKWHLG--------ATIETSPWARGFERSFAL
                                       : . *   *: *   ** *          ..    *   **:: :.:

Mb3327c|M.bovis_AF2122/97           PSGAAGQYDPIISQDNSVIGIPEGSG---EDGRPYYFPDDLTDKAIEWLH
Rv3299c|M.tuberculosis_H37Rv        PSGAAGQYDPIISQDNSVIGIPEGSG---EDGRPYYFPDDLTDKAIEWLH
MMAR_1232|M.marinum_M               PSGAAGQYDPIITQDNSVLGIPQG-----DDGKPYFFPDDLTDKAIEWLH
MUL_2658|M.ulcerans_Agy99           PSGAAGQYDPIITQDNSVLGIPQG-----DDGKPYFFPDDLTDKAIEWLH
Mvan_4467|M.vanbaalenii_PYR-1       IGGEANQYYPGLYEGTKPVEPEKT------PEQGYTLTEDLADRAITWVR
Mflv_5039|M.gilvum_PYR-GCK          MGGETDQWYPDLMYDNHPVAPPAT------PEEGYHLSKDLADKTIEFIR
MSMEG_1451|M.smegmatis_MC2_155      MGGETDQWYPDLTYDNHPVDPPAT------PEEGYHLSKDLADKTIEFIR
TH_0315|M.thermoresistible__bu      LGGETDQWYPDLVHDNHPVAPPAT------PEDGYHLSKDLADKTIEFIR
MAB_4307|M.abscessus_ATCC_1997      LGGETNNWYPDLVEDNRFIEQPTS------PEQGYHLSKDLADQALRMLR
MAV_2989|M.avium_104                LPAGASHYGGSGARGFSPVPTLYTEDDRFVSVGDDFYSSDSYTDTLLRYL
                                      . :.::      .   :                  ..*    ::    

Mb3327c|M.bovis_AF2122/97           TVRAQNATKPWMLYYATGATHAPHHVFKEWADKYRGEFDDGWDVYRQKTF
Rv3299c|M.tuberculosis_H37Rv        TVRAQNATKPWMLYYATGATHAPHHVFKEWADKYRGEFDDGWDVYRQKTF
MMAR_1232|M.marinum_M               TVRAQNATKPWLLYYSTGATHAPHHVFKEWADKYQGQFDEGWDVYRQKTF
MUL_2658|M.ulcerans_Agy99           TVRAQNATKPWLLYYSTGATHAPHHVFKEWADKYQGQFDEGWDVYRQKTF
Mvan_4467|M.vanbaalenii_PYR-1       QQQALTPDKPFFMYFAPGATHAPHHVPKQWSDKYRGKFDDGWDVLRESML
Mflv_5039|M.gilvum_PYR-GCK          DSKVIAPDKPWFSYVCPGAGHAPHHVFKEWADRYAGRFDMGYEAYREIVL
MSMEG_1451|M.smegmatis_MC2_155      DAKVVASDKPWFTYLCPGAGHAPHHVFKEWADRYKGRFDMGYERYREIVL
TH_0315|M.thermoresistible__bu      DAKVIAPDKPWFTYLCPGAGHAPHHAPRDWADRYAGRFDMGYERYREVVL
MAB_4307|M.abscessus_ATCC_1997      DQRNTNPSKPWYMWFCPGANHAPHHSPAEYADKYRGKFDDGYEAYREWVL
MAV_2989|M.avium_104                DERAPDDDRPFFAYLPFQAPHWPLQAPDESIAKYRGRYDEGPDVLRAERL
                                      :     :*:  :    * * * :   :   :* *.:* * :  *   :

Mb3327c|M.bovis_AF2122/97           ERQKRLGIIPPDAELTERP----------------DLFPAWDSMSEAQKR
Rv3299c|M.tuberculosis_H37Rv        ERQKRLGIIPPDAELTERP----------------DLFPAWDSMSEAQKR
MMAR_1232|M.marinum_M               ERQKELGIIPPDAELTERP----------------DLFPAWDSLSEAQQK
MUL_2658|M.ulcerans_Agy99           ERQKELGIIPPDAELTERP----------------DLFPAWDSLSEAQQK
Mvan_4467|M.vanbaalenii_PYR-1       DNQKALGVVPEDAQLTARH----------------DEIPAWDDMPDVLKP
Mflv_5039|M.gilvum_PYR-GCK          ENQKRLGLVPPDTELSAVNPYLDVKGPDGQDWPAQDTVRPWDSLSEDEKR
MSMEG_1451|M.smegmatis_MC2_155      ENQKRMGLVPPDTELSPVNPYSEVTGPDGQPWPAQDTVRPWDSLSDDEKA
TH_0315|M.thermoresistible__bu      ENQKKLGIVPPDTELPPINPYQDVKGPHGEPWPLQDTVRPWDSLSDAEKR
MAB_4307|M.abscessus_ATCC_1997      ARMIDKGIMPRETKLTPINPLPNDVAVEA------DSVRPWNTLNPDEKR
MAV_2989|M.avium_104                AALKRLGLCPPDVTPHPVVA---------------DGAPEWADMTDEERA
                                          *: * :.                      *    *  :    : 

Mb3327c|M.bovis_AF2122/97           LFARQMEVFAGFSENADWNVGRLLDAIEDLGESDNTLVFYIWGDNGASME
Rv3299c|M.tuberculosis_H37Rv        LFARQMEVFAGFSENADWNVGRLLDAIEDLGESDNTLVFYIWGDNGASME
MMAR_1232|M.marinum_M               LFARQMEVFAGFSENADWNVGRLLDAIDGLGESDNTLVFYIWGDNGASME
MUL_2658|M.ulcerans_Agy99           LFARQMEVFAGFSENADWNVGRLLDAIDGLGESDNTLVFYIWGDNGASME
Mvan_4467|M.vanbaalenii_PYR-1       VLARQMEIYAGFLEQTDHEIGRLVDAIDDLGALDNTLIYYIIGDNGASAE
Mflv_5039|M.gilvum_PYR-GCK          LFARMAEVFAGFLSYTDAQIGRVLDYLEESGQLDNTVIVVIS-DNGASGE
MSMEG_1451|M.smegmatis_MC2_155      LFCRMAEVFAGFLSYTDAQIGRVLDYLEESGQIDNTIIVVIS-DNGASGE
TH_0315|M.thermoresistible__bu      LFCRMAEVFAGFLSYTDHQIGRVLDYLEESDQLDNTLIVVLS-DNGASGE
MAB_4307|M.abscessus_ATCC_1997      LFSRMAEVFAGFSEYTDAQVGRVIDYLEQTGQLDNTVVFYCA-DNGASGE
MAV_2989|M.avium_104                RSARTMEVYAGMVDRMDYNVGRVIDYLSRSGELDNTVVIFLS-DNGAEG-
                                      .*  *::**: .  * ::**::* :.  .  ***::     ****.  

Mb3327c|M.bovis_AF2122/97           GTNTGSFNEMTFLNGLD--LDAERQLELIEQYGGIAALGDEFTAPHFASA
Rv3299c|M.tuberculosis_H37Rv        GTNTGSFNEMTFLNGLD--LDAERQLELIEQYGGIAALGDEFTAPHFASA
MMAR_1232|M.marinum_M               GTNTGSFNEMTFLNGLD--LDAERQLELIEQYGGIEALGDEFTAPHFASA
MUL_2658|M.ulcerans_Agy99           GTNTGSFNEMTFLNGLD--LDAERQLELIEQYGGIEALGDEFTAPHFASA
Mvan_4467|M.vanbaalenii_PYR-1       GTPNGCFNEMCTLNGLAGIETPEFLLSKIDDFGTPDAYN------HYAVG
Mflv_5039|M.gilvum_PYR-GCK          GGPNGSVNEVKFFNGYI--DSAEESLKVFDELGGPQTYN------HYPIG
MSMEG_1451|M.smegmatis_MC2_155      GGPNGSVNETKFFNGYI--DTAEEGLKFIDKLGGPQTYN------HYPIG
TH_0315|M.thermoresistible__bu      GGPDGSVNEVKFFNGYV--DTVEESMRFYDQLGGPQTYN------HYPTG
MAB_4307|M.abscessus_ATCC_1997      GSPNGSVNENKFFNGYP--DDLAENMKYIDRLGTPDTYN------HYPTG
MAV_2989|M.avium_104                ----AIVEAMPLRGPQIAAQIEKHCDNSLDNLGRPTSFI------WYGPR
                                        . .:     .               :  *   :         :   

Mb3327c|M.bovis_AF2122/97           WAHASNTPLQWGKQMASHLGGTRDPLVVAWPARIRPDGRVRSQFTHCIDI
Rv3299c|M.tuberculosis_H37Rv        WAHASNTPLQWGKQMASHLGGTRDPLVVAWPARIRPDGRVRSQFTHCIDI
MMAR_1232|M.marinum_M               WAHANNTPFQWGKQMASHLGGTRDPMVVCWPSRIPREGGIRSQFTHCIDI
MUL_2658|M.ulcerans_Agy99           WAHANNTPFQWGKQMASHLGGTRDPMVACWPSRIPREGGIRSQFTHCIDI
Mvan_4467|M.vanbaalenii_PYR-1       WAHALCGPYQWTKQVASHWGGTRNGTIVHWPNGIAAKGETRNQFHHVIDV
Mflv_5039|M.gilvum_PYR-GCK          WAMAFNTPYKLFKRYASHEGGIADTAIISWPKGIAAHGEIRDNYVNVADI
MSMEG_1451|M.smegmatis_MC2_155      WAMAFNTPYKLFKRYASHEGGIADPAIISWPKGIAARGEVRDNYVNVCDV
TH_0315|M.thermoresistible__bu      WAMAFNTPYKLFKRYASHEGGIADPAIISWPNGITARDAVCDRYINVVDV
MAB_4307|M.abscessus_ATCC_1997      WAVAFSTPFQMFKRYSQFSGGTCDPLVIHWPKGIKAKGEVRHQYHHVTDI
MAV_2989|M.avium_104                WAQAATAPSRLHKAFTTQGG-IRVPGFITWPG-FARQGQIGTAFSTVMDI
                                    ** *   * :  *  :   *      .  **  :   .     :    *:

Mb3327c|M.bovis_AF2122/97           APTVLAAIGLPEP-THVDGFEQEPMDGTSFVRTFD--DAEAEDRHTVQYF
Rv3299c|M.tuberculosis_H37Rv        APTVLAAIGLPEP-THVDGFEQEPMDGTSFVRTFD--DAEAEDRHTVQYF
MMAR_1232|M.marinum_M               APTVLQAIGLPEP-TSVDGFEQEPMDGTSFVHTFD--DAQAEERHTVQYF
MUL_2658|M.ulcerans_Agy99           APTVLQAIGLPEP-TSVDGFEQEPMDGTSFVHTFD--DAQAEERHTVQYF
Mvan_4467|M.vanbaalenii_PYR-1       VPTILEAAKLPAP-TVVNSIQQAPLEGVSMMSTLR--DRDADETHTVQYF
Mflv_5039|M.gilvum_PYR-GCK          TPTVYDLLDITPP-ATVRGVAQKPLDGVSFKVALE--NPNAPTGKETQFY
MSMEG_1451|M.smegmatis_MC2_155      TPTVYDMLGITPP-ATVRGVPQKPLDGVSFKAALA--DPDAPTGKETQFY
TH_0315|M.thermoresistible__bu      TPTVYELIGLTPP-DTVRGVRQRPLEGVSFRAALA--DPDADTGKRTQFY
MAB_4307|M.abscessus_ATCC_1997      VPTILDVAGLTMP-ETYRGVDQFPVNGVSMRYTFD--DKDAATTKKRQYY
MAV_2989|M.avium_104                APTLLELAGTSHPGTAYRGREVAPMRGRSLVGYLSGAADTVHDADTETGW
                                    .**:      . *     .    *: * *:   :      .   .    :

Mb3327c|M.bovis_AF2122/97           ENFGSRAIYKDGWWACARLDKAPWDLSPETMRRFAPGTYDPDQDVWELYY
Rv3299c|M.tuberculosis_H37Rv        ENFGSRAIYKDGWWACARLDKAPWDLSPETMRRFAPGTYDPDQDVWELYY
MMAR_1232|M.marinum_M               ENFGSRSIYQDGWWACARLDKAPWDLSPQTMARFSPGNYDPEKDVWELYY
MUL_2658|M.ulcerans_Agy99           ENFGSRSIYQDGWWACARLDKAPWDLSPQTMARFSPGNYDPEKDVWELYY
Mvan_4467|M.vanbaalenii_PYR-1       EMFGNRGIYHKGWTAVT-KHRTPWIADQPPL----------DEDVWELY-
Mflv_5039|M.gilvum_PYR-GCK          TMLGTRGIWHRGWFANTVHAASPAGWS------------HFDDDRWELYH
MSMEG_1451|M.smegmatis_MC2_155      AMLGTRGIWHKGWFANTVHAATPSGWG------------HFADDRWELFH
TH_0315|M.thermoresistible__bu      SMLGTRGIWSDGWFANTVHAASPAGWS------------NFDADRWELYH
MAB_4307|M.abscessus_ATCC_1997      AMLGTRGIWEDGWKASALHAP-ISGKG------------HFDQDKWELFH
MAV_2989|M.avium_104                ELFGRRAIRQGNWKALHLPAP-------------------YGPGSWQLYD
                                      :* *.*   .* *                            . *:*: 

Mb3327c|M.bovis_AF2122/97           LPDDFSQAKNLAAEHPDKVAELTQLWWQEAERNRVLPLLGGLAVMFG---
Rv3299c|M.tuberculosis_H37Rv        LPDDFSQAKNLAAEHPDKVAELTQLWWQEAERNRVLPLLGGLAVMFG---
MMAR_1232|M.marinum_M               LPDDFSQARNVAAEHPDKLAELRELWWQEAERNRVLPLLGGLAVMYG---
MUL_2658|M.ulcerans_Agy99           LPDDFSQARNVAAEHPDKLAELRELWWQEAERNRVLPLLGGLAVMYG---
Mvan_4467|M.vanbaalenii_PYR-1       APDDWTQAHDLAAEQPERLAALQRLWLIEAVKYNVVPLDDRSFERFNPDI
Mflv_5039|M.gilvum_PYR-GCK          VDADRSQVHDLAAEYPEKLDELKALWFSEAQKYNGLPLGDLDIFETMS--
MSMEG_1451|M.smegmatis_MC2_155      IDADRSQCHDLAAEHPDRLEELKALWFSEADKYNGLPLGDLSILETTT--
TH_0315|M.thermoresistible__bu      LESDRSQSRDLAAEHPEKLEELKQLWFDEAAKYNGLPLGDLNLFETLG--
MAB_4307|M.abscessus_ATCC_1997      VDEDRSESTDLADQHPDKLKALIDAWFEEADNNFVLPLDDRLPTELLT--
MAV_2989|M.avium_104                LASDPGEVDDLAAARPDKLAELLALWDRYVEETGVILDPISVFDAEL---
                                       *  :  ::*   *:::  *   *   . .   :              

Mb3327c|M.bovis_AF2122/97           -DLPPLP-TTARFSFKGDVQNIQRGMVPRICGRSYAIEARLHIPDGGAQG
Rv3299c|M.tuberculosis_H37Rv        -DLPPLP-TTARFSFKGDVQNIQRGMVPRICGRSYAIEARLHIPDGGAQG
MMAR_1232|M.marinum_M               -ELPPLP-TTTRFAFQGGVQNIQRGMVPRVFGRSYAIEARLHIPDGGAEG
MUL_2658|M.ulcerans_Agy99           -ELPPLP-TITRFAFQGGVQNIQRGMVPRVFGRSYAIEARPHIPDGGAEG
Mvan_4467|M.vanbaalenii_PYR-1       AGRPQLI-KGTTQTLFSGMRLLEN-CVLNIKNRSHAVSALISVPDSGAQG
Mflv_5039|M.gilvum_PYR-GCK          RWRPTLSGERSAYVYYPGTADVGIGAVVELRGRSFAVLAEVEVDPGGANG
MSMEG_1451|M.smegmatis_MC2_155      RWRPYLTGERTSYTYYPHTAEVGMGAVVELRGQSFKVLAEVTVDSAEAQG
TH_0315|M.thermoresistible__bu      RWRPHLSRGRTSYTYYPGTAEVGLGAAVDIRGQSFTVLADVTVDAAGAQG
MAB_4307|M.abscessus_ATCC_1997      IERPQFEPRRNRYLYYPDASPVPEGVAVNIRGKSYKIVANTDIS-AQAQG
MAV_2989|M.avium_104                --------------------------------------------------
                                                                                      

Mb3327c|M.bovis_AF2122/97           VIVANADFMGGFALWVDEQRHLHHTYSFLGVETYRQVSSEPLPTGDVTVR
Rv3299c|M.tuberculosis_H37Rv        VIVANADFMGGFALWVDEQRHLHHTYSFLGVETYRQVSSEPLPTGDVTVR
MMAR_1232|M.marinum_M               VIVANADFMGGFALWVDEQRRLHHTYSFLGIETYRQVSTEPVPTGDVTVR
MUL_2658|M.ulcerans_Agy99           VIVANADFMGGFALWVDEQRRLHHTYSFLGIETYRQVSTEPVPTGDVTVR
Mvan_4467|M.vanbaalenii_PYR-1       VIVSQGGGVGGWCVYAHEN-TLKYCYNFFGIEYYFVTAELPLPGGQHLVG
Mflv_5039|M.gilvum_PYR-GCK          VVVKHGGAHGGYVMYLQGG-RLHFCYNFLGEYEQTLAAPDPVPPGLHTLG
MSMEG_1451|M.smegmatis_MC2_155      VIFKHGGAHGGHVLFIADG-HLHYVYNFLGEREQVLSAPDPVPLGHHIFG
TH_0315|M.thermoresistible__bu      VIVKHGAGHGGYVLFLQDG-RLHFVYNFMGEEEQRVSSADPIPAGRHILG
MAB_4307|M.abscessus_ATCC_1997      VIFAHGSRFGGHVLFIKDG-RLHYVYNFLGIKPEQEFISAPLTPGNRTLG
MAV_2989|M.avium_104                --------------------------------------------------
                                                                                      

Mb3327c|M.bovis_AF2122/97           MLFDSHQPV---AASGGRVTLWADDRLIGEGELPQTVPLAFTSYAG-MDI
Rv3299c|M.tuberculosis_H37Rv        MLFDSHQPV---AASGGRVTLWADDRLIGEGELPQTVPLAFTSYAG-MDI
MMAR_1232|M.marinum_M               MLFESEAPV---IGSGGRVTLWANDRLIGEGELPQTVTLAFTSYAG-LDV
MUL_2658|M.ulcerans_Agy99           MLFESEAPV---VGSGGRVTLWANDRLIGEGELPQTVTLAFTSYAG-LDV
Mvan_4467|M.vanbaalenii_PYR-1       FEFAYDGGG---LGKGGTVTLYCDGEPVGTGRVERTEPMAFSADEA-CDV
Mflv_5039|M.gilvum_PYR-GCK          FTYTVTGTAEGSHTPIGDAELFLDTERVASLAEMRSQPGTFGLAGASLSV
MSMEG_1451|M.smegmatis_MC2_155      VRYERTGTVPNSHTPVGVATLFVDGGAVADLADVQTHPAIFALAGGGIAV
TH_0315|M.thermoresistible__bu      VSYHRTGTVDGSHTPLGEVALYVDGTVVATRPDVRAHPANFGLAGGGIAV
MAB_4307|M.abscessus_ATCC_1997      VEFVRRDKGQYGES-LGTTNLYVDG-KLAATGPMRTQVGTFTLAGDGLCV
MAV_2989|M.avium_104                --------------------------------------------------
                                                                                      

Mb3327c|M.bovis_AF2122/97           GRDNGLVVDRGYEDKAPYAFTG-TVTEVIFDLKPVHPEAARALHEHASVQ
Rv3299c|M.tuberculosis_H37Rv        GRDNGLVVDRGYEDKAPYAFTG-TVTEVIFDLKPVHPEAARALHEHASVQ
MMAR_1232|M.marinum_M               GRDNGLVVDRDYEDKAPYTFSG-TVKEVVFDLKPVHPDAEKALHEHASIQ
MUL_2658|M.ulcerans_Agy99           GRDNGLVVDRDYEDKALYMFSG-TVKEVVFDLKPVHPDAEKALHEHASIQ
Mvan_4467|M.vanbaalenii_PYR-1       GSDTGSPTSPDYGPHG-NGFNG-RIDWVKIDISTDDHEHLITPQDRFNIS
Mflv_5039|M.gilvum_PYR-GCK          GRNNGSPVSEAYHPPF--AFAGGRIARVNIDTS---GAPYVDLERDFARA
MSMEG_1451|M.smegmatis_MC2_155      GRNTGSGVSRSYRVPF--PFTGGEIAQVTVDLS---GEPYEDLVTRRATA
TH_0315|M.thermoresistible__bu      GRNTGQPVSSAYRAPF--AFTGGSIAKVIVDIS---GTPYRDVEREAAMA
MAB_4307|M.abscessus_ATCC_1997      GYDSGDNVSPQYTNPG--RFTGGTIKVVAVDVS---DESFIDLEKEAQAA
MAV_2989|M.avium_104                --------------------------------------------------
                                                                                      

Mb3327c|M.bovis_AF2122/97           AVGQGAAG
Rv3299c|M.tuberculosis_H37Rv        AVGQGAAG
MMAR_1232|M.marinum_M               AVGQGAAG
MUL_2658|M.ulcerans_Agy99           AVGQGAAG
Mvan_4467|M.vanbaalenii_PYR-1       MARQ----
Mflv_5039|M.gilvum_PYR-GCK          FARD----
MSMEG_1451|M.smegmatis_MC2_155      FARD----
TH_0315|M.thermoresistible__bu      FARD----
MAB_4307|M.abscessus_ATCC_1997      FARD----
MAV_2989|M.avium_104                --------