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AELNRRTVLTTGAIAAGAAAVGFGGYELLGTPRRNSSSGSDGNKPNILVIVVDQMRAPQWFPDVQKLTNI LPNLSRLHRDSVSFASHYTASNMCTPSRGAMTTGLYSHQTGCLYTGEGPSESSLAPQFPTWGTMLRQQGY RTWWWGKWHLGDWSDTNPEGLDAHGFSGGTFPSPNGMPNQGLQKDPGIVDQFAGWFDAEAGKGPWCTTVS LVNPHDICWWPKNPLPEDVPHWFDGLPVNFQTPDELRQHGKPRLQIDYANFMSPIMTGAVTYSGPDMARQ WARCLDMYLWLQQQVDAQIGRVLDKLASRPEIDGNTIVVFTSDHGEYAGSHGLRGKGATAYEEAIRVPLY IRDPQGVLTPKPGETRTQLTSSVDLAPLLLTIGSGGNAWRSDPRFSYLAARADIAAIAKNNAAGRKWIAH VTDDMSVEEMATLLKDPRIRAVMGENAPTEIPTSAASHIVAVRTAEAKLANYSYWKPGGMRIDTSRPSEH EFYDYSTPSGKQESQNQAGDSTKQAQLQALIDNEVLPEVQAPLPAFLGQAQEQGLADMQKLMVLRGG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_4469c | - | - | 100% (558) | sulfatase family protein |
M. abscessus ATCC 19977 | MAB_4307 | - | 1e-11 | 22.60% (354) | arylsulfatase AtsA |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3104 | - | 5e-30 | 31.23% (397) | hydrolase |
M. gilvum PYR-GCK | Mflv_2372 | - | 5e-28 | 30.75% (400) | sulfatase |
M. tuberculosis H37Rv | Rv3077 | - | 1e-29 | 31.25% (400) | hydrolase |
M. leprae Br4923 | - | - | - | - | - |
M. marinum M | MMAR_1577 | - | 1e-27 | 29.44% (394) | hydrolase |
M. avium 104 | MAV_2989 | - | 7e-11 | 25.30% (332) | arylsulfatase |
M. smegmatis MC2 155 | MSMEG_1286 | - | 6e-28 | 30.75% (400) | sulfatase family protein |
M. thermoresistible (build 8) | TH_0121 | atsF | 1e-28 | 29.95% (414) | POSSIBLE HYDROLASE |
M. ulcerans Agy99 | MUL_3457 | - | 7e-28 | 29.44% (394) | hydrolase |
M. vanbaalenii PYR-1 | Mvan_4274 | - | 1e-32 | 31.99% (397) | sulfatase |
CLUSTAL 2.0.9 multiple sequence alignment Mb3104|M.bovis_AF2122/97 -------------------------------------------------- Rv3077|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1577|M.marinum_M -------------------------------------------------- MUL_3457|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_1286|M.smegmatis_MC2_155 -------------------------------------------------- TH_0121|M.thermoresistible__bu VAVFSRARTIPAGTERIWELLGDVGALSSWARLVDHSCVLTTGPHGDLIG Mflv_2372|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4274|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4469c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2989|M.avium_104 -------------------------------------------------- Mb3104|M.bovis_AF2122/97 -------------------------------------------------- Rv3077|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1577|M.marinum_M -------------------------------------------------- MUL_3457|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_1286|M.smegmatis_MC2_155 -------------------------------------------------- TH_0121|M.thermoresistible__bu TTRRVQIGRTTLVERITEFDPPRALSYQICGLPPQLGNVVNRWVLSPTAG Mflv_2372|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4274|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4469c|M.abscessus_ATCC_199 -------------------------MAELNRRTVLTTGAIAAGAAAVGFG MAV_2989|M.avium_104 -------------------------------------------------- Mb3104|M.bovis_AF2122/97 ----------------MANRPDIIIVMTDEERAVPPYESAEVLAWRQRSL Rv3077|M.tuberculosis_H37Rv ----------------MANRPDIIIVMTDEERAVPPYESAEVLAWRQRSL MMAR_1577|M.marinum_M ----------------MPEGPDIVIIMTDEERAVPPYESADVLAWRQRTL MUL_3457|M.ulcerans_Agy99 ----------------MPEGPDIVIIMTDEERAVPPYESADVLAWRQRTL MSMEG_1286|M.smegmatis_MC2_155 ----------------MTDRPDIVIVMTDEERAIPPYESSSVLAWRERVL TH_0121|M.thermoresistible__bu GTVVTLTTTVXXSRPDSGGRPDIVIVMTDEERAIPPYESDDLLAWRDQTL Mflv_2372|M.gilvum_PYR-GCK ---------------MTAQRPDVVIVMTDEERAIPPYESDRVRTWRDETL Mvan_4274|M.vanbaalenii_PYR-1 ---------------MTTERPDIVVVMTDEERATPPYEPDTVRAWRSRTL MAB_4469c|M.abscessus_ATCC_199 GYELLGTPRRNSSSGSDGNKPNILVIVVDQMRAPQWFPDVQKLTN---IL MAV_2989|M.avium_104 -----------------MKRPNFLVIVADDLGFSDLGAFG-----GEIET *:.::::.*: Mb3104|M.bovis_AF2122/97 TGRRWFDEHGISFTRHYTGSLACVPSRPTIFTGQYPDLHGVTQTDGIGKR Rv3077|M.tuberculosis_H37Rv TGRRWFDEHGISFTRHYTGSLACVPSRPTIFTGQYPDLHGVTQTDGIGKR MMAR_1577|M.marinum_M TGRRWFDEHGVSFARHYTGSLACVPSRPTIFTGQYPDLHGVTQTDGIGKR MUL_3457|M.ulcerans_Agy99 TGRRWFDEHGVSFARHYTGSLACVPSRPTIFTGQYPDLHGVTQTDGIGKR MSMEG_1286|M.smegmatis_MC2_155 TGRRWFDEHGVNFTRHYTGSLACVPSRPTMFTGHYPDLHGITQTDGLGKR TH_0121|M.thermoresistible__bu AGRRWFDEHGVTFTRHYTGSLACVPSRPTIFTGHYPDLHGVTQTDGLGKS Mflv_2372|M.gilvum_PYR-GCK TGRRWFEEHGVSFTRHYTGSLACVPSRPTIFTGHYPDLHGVTQTDGIGKS Mvan_4274|M.vanbaalenii_PYR-1 GGRRWFDENGVSFLRHYTGSLACVPSRPTIFTGQYPDLHGVTQTDGIGKA MAB_4469c|M.abscessus_ATCC_199 PNLSRLHRDSVSFASHYTASNMCTPSRGAMTTGLYSHQTGCLYTG----- MAV_2989|M.avium_104 PNLDRLAYAGIRLTDFHS-APACSPTRAMLLTGTDHHIAGIGTMLEVAAP . : .: : .:: : * *:* : ** . * Mb3104|M.bovis_AF2122/97 FDDSRLRWL--RAGEVPTLGNWFRAAGYDTHYDGKWHISHADLEDPATGA Rv3077|M.tuberculosis_H37Rv FDDSRLRWL--RAGEVPTLGNWFRAAGYDTHYDGKWHISHADLEDPATGA MMAR_1577|M.marinum_M FDDSRLRWL--RAGEVPTLGNWFRAAGYDTHYDGKWHISHADLEDPDTGL MUL_3457|M.ulcerans_Agy99 FDDSRLRWL--RAGEVPTLGNWFRAAGYDTHYDGKWHISHADLEDPDTGL MSMEG_1286|M.smegmatis_MC2_155 YDDSRLRWL--RRGEVPTLGNWFRAAGYDTHYDGKWHISHADLEDPATGE TH_0121|M.thermoresistible__bu HDDSRMRWL--RRGEVPTLGHWFRAAGYDTHYDGKWHISHADLTDPRTGR Mflv_2372|M.gilvum_PYR-GCK HDDSRLRWL--RRGEVPTLGNWFRAAGYDTHYDGKWHISHADLTDPSTGR Mvan_4274|M.vanbaalenii_PYR-1 HDDSRLRWL--RRGEVPTLGNWLRAAGYDTHYDGKWHISHADLIDPGTGR MAB_4469c|M.abscessus_ATCC_199 --EGPSESS--LAPQFPTWGTMLRQQGYRTWWWGKWHLGDWSDTNP---- MAV_2989|M.avium_104 QFHGAPGYEGYLNDRVVALPELLRDAGYLTLMSGKWHLGATIETSP---- .. .. : :* ** * ****:. .* Mb3104|M.bovis_AF2122/97 PLATNDNEGVVDSAAVRRYLDADPLGPYGFSGWVGPEPHGAGLANSGFRR Rv3077|M.tuberculosis_H37Rv PLATNDNEGVVDSAAVRRYLDADPLGPYGFSGWVGPEPHGAGLANSGFRR MMAR_1577|M.marinum_M SLATNDDDGEIDPAAVQRYLDADPLGPYGFSGWVGPEPHGAGNANSGFRR MUL_3457|M.ulcerans_Agy99 SLATNDDDGEIDPAAVQRYLDADPLGPYGFSGWVGPEPHGAGNANSGFRR MSMEG_1286|M.smegmatis_MC2_155 PLATNDDDGVIDHAAVQAYLEADPLAPFGFSGWVGPEPHGAAMSNSGFRR TH_0121|M.thermoresistible__bu PLATNDDDGVVDPAAVQRYLDADPLDPFGFSGWVGPEPHGAGLANSGLRR Mflv_2372|M.gilvum_PYR-GCK PLATNDSDGVVDPGAVKRYLDADPLAPYGFSGWVGPEPHGAGLANAGIRR Mvan_4274|M.vanbaalenii_PYR-1 SLDTNDDDGVVDPAAVHRYLEADPLSPYGFSGWVGPEPHGAKLSNAGIRR MAB_4469c|M.abscessus_ATCC_199 ----------------------EGLDAHGFSGGTFPSPN--GMPNQGLQK MAV_2989|M.avium_104 -WARGFERSFALLPAGASHYGGSGARGFSPVPTLYTEDDRFVSVGDDFYS . .. .. . . .: Mb3104|M.bovis_AF2122/97 DPLVADRVVAWLTERYARRRAGDTAAMRPFLLVASFVNPHDIVLFPAWVW Rv3077|M.tuberculosis_H37Rv DPLVADRVVAWLTERYARRRAGDTAAMRPFLLVASFVNPHDIVLFPAWVW MMAR_1577|M.marinum_M DPLIADRVVAWLEDRYARRRAGDEAALRPFLLVASFINPHDVVLFPAWVR MUL_3457|M.ulcerans_Agy99 DPLIADRVVAWLEDRYARRRAGDEAALRPFLLVASFINPHDVVLFPAWVR MSMEG_1286|M.smegmatis_MC2_155 DPIVADRVVAWLKDRYARRRAGDPDALRPFLLVASFVNPHDIVLFPAWSR TH_0121|M.thermoresistible__bu DPLIADRVVAWLRDRYERRRAGDPDALRPFLLVASFVNPHDIVLFPTWAR Mflv_2372|M.gilvum_PYR-GCK DPLIADRVVAWLTARYAARAAGDSAALRPFLLVASFVNPHDIVLFPAWAR Mvan_4274|M.vanbaalenii_PYR-1 DPLIADRVVAWLKDRYARRRAGDPDAMRPFLLVASFVNPHDIVLFPAWAR MAB_4469c|M.abscessus_ATCC_199 DPGIVDQFAGWFDAEAGKG---------PWCTTVSLVNPHDICWWPKNP- MAV_2989|M.avium_104 SDSYTDTLLRYLDERAPDDD-------RPFFAYLPFQAPHWPLQAPDESI . .* . :: . *: .: ** * Mb3104|M.bovis_AF2122/97 RSPLKPSPLDPPHVPAAPTADEDLSTKPAAQVAYREAYYSGYGLTRMVSR Rv3077|M.tuberculosis_H37Rv RSPLKPSPLDPPHVPAAPTADEDLSTKPAAQVAYREAYYSGYGLTRMVSR MMAR_1577|M.marinum_M FSPLKPSHLDPPHVPAPPTADEDLRTKPAAQIAFRQAYYTGYGVAPAIKR MUL_3457|M.ulcerans_Agy99 FGPLKPSHLDPPHVPAPPTADEDLRTKPAAQIAFRQAYYTGYGVAPAIKR MSMEG_1286|M.smegmatis_MC2_155 RMPFGPSELDPPHVPAAPTAEEDLRDKPAAQIAFREAYYTGYGPAMAVER TH_0121|M.thermoresistible__bu RSPLSPGPLDPPPVPPAPTADEDLSDKPAAHIAFREAYYSGYGPAWFVQR Mflv_2372|M.gilvum_PYR-GCK RNPLSPSPLDPPSVPPAPTADEDLSTKPAAQIAFREAYYSGYGPAGSIER Mvan_4274|M.vanbaalenii_PYR-1 RNPLPASPLDPPPVPAAPTADEDLSTKPAAQIAFREAYYSGYGPAWSIER MAB_4469c|M.abscessus_ATCC_199 LPEDVPHWFDGLPVNFQTPDELRQHGKPRLQIDYANFMSPIMTGAVTYSG MAV_2989|M.avium_104 AKYRGRYDEGPDVLRAERLAALKRLGLCPPDVTPHPVVADGAPEWADMTD . : .: Mb3104|M.bovis_AF2122/97 -NYARNAQRYRDLYYRLHAEVDGPIDRVRRAVTEGG----SEDAMLVRTS Rv3077|M.tuberculosis_H37Rv -NYARNAQRYRDLYYRLHAEVDGPIDRVGRAVTEGG----SEDAMLVRTS MMAR_1577|M.marinum_M -TYQRNAQRYRDLYYRLHAENDGPIDRVRRAVTEGG----SDNAVLVRTS MUL_3457|M.ulcerans_Agy99 -TYQRNAQRYRDLYYRLHAENDGPIDRVRRAVTEGG----SDNAVLVRTS MSMEG_1286|M.smegmatis_MC2_155 -TYRRKAQQYRDLYYRLHAEVDGPIDRVRRAVTEGG----SENAVLVRTS TH_0121|M.thermoresistible__bu -TYERNAQRYRDLYYRLHAEVDGPIDRVRRAVTAG-----SHNAVLVRTS Mflv_2372|M.gilvum_PYR-GCK -TYRRNAQRYRDLYYRLHAEVDEPIDRVRRAVTDG---AGAHPTVLVRTA Mvan_4274|M.vanbaalenii_PYR-1 -TYRRNAQRYRDLYYRLHAEVDTPIDRVRRAVTEGGSGDGPDDTVLVRTA MAB_4469c|M.abscessus_ATCC_199 PDMARQWARCLDMYLWLQQQVDAQIGRVLDKLASRP--EIDGNTIVVFTS MAV_2989|M.avium_104 -EERARSARTMEVYAGMVDRMDYNVGRVIDYLSRSG---ELDNTVVIFLS . : ::* : . * :.** :: :::: : Mb3104|M.bovis_AF2122/97 DHGDLLGAHGGLHQKWFNLYDEATRVPFVIARIG--EKATQPRTVSAPTS Rv3077|M.tuberculosis_H37Rv DHGDLLGAHGGLHQKWFNLYDEATRVPFVIARIG--EKATQPRTVSAPTS MMAR_1577|M.marinum_M DHGDLLGAHGGLHQKWFNLYDEATRVPFVIARVG--DEATTARTVSAPTS MUL_3457|M.ulcerans_Agy99 DHGDLLGAHGGLHQKWFNLYDEATRVPFVITRVG--NEATTARTVSAPTS MSMEG_1286|M.smegmatis_MC2_155 DHGELLGAHGGLHQKWFNLYDEATRVPFVIARIG--TEATEARTVDAPTS TH_0121|M.thermoresistible__bu DHGELLGAHGGLHQKWFNLYDEATRVPFVIARIG--DRATEARTVTAPTS Mflv_2372|M.gilvum_PYR-GCK DHGDLLGAHGGLHQKWFNLYDEATRVPFVIARTG--PDATTARTVTAPTS Mvan_4274|M.vanbaalenii_PYR-1 DHGDLLGAHGGLHQKWFNLYDEATRVPFVIARVG--ARPTTARTVTAPTS MAB_4469c|M.abscessus_ATCC_199 DHGEYAGSHG-LRGKGATAYEEAIRVPLYIRDPQGVLTPKPGETRTQLTS MAV_2989|M.avium_104 DN----GAEGAIVEAMP------LRGPQIAAQIEK-HCDNSLDNLGRPTS *: *:.* : * * . . ** Mb3104|M.bovis_AF2122/97 HVDLVPTLLSAAGVDVDVVAAALAESFSEVHPLPGRDLMPVVDGASADEG Rv3077|M.tuberculosis_H37Rv HVDLVPTLLSAAGVDVDVVAAALAESFSEVHPLPGRDLMPVVDGASADEG MMAR_1577|M.marinum_M HVDLVPTLLSAAGIDTDAVAANLAESFTEVHPLPGRDLMAVVDGAPADED MUL_3457|M.ulcerans_Agy99 HVDLVPTLLSAAGIDTEAVAANLAESFTEVHPLPGRDLMAVVDGAPADED MSMEG_1286|M.smegmatis_MC2_155 HVDLVPTLLGAAGVDVDAAAEQLRESFSEVHPLPGRDLMPVVSGESADEH TH_0121|M.thermoresistible__bu HVDLVPTLLGAAGVDVDAAAARLAESFTEVHPLPGRDLMPVVDGAPADEN Mflv_2372|M.gilvum_PYR-GCK HVDLVPTLLAAAGIDAESVAATLGESFTEVHPLPGRDLMPVVDGAPADED Mvan_4274|M.vanbaalenii_PYR-1 HVDLVPTLLSAAGVDVDAAATVLAESFSEVHPLPGSDLMPVVDGAPADDH MAB_4469c|M.abscessus_ATCC_199 SVDLAPLLLTIG------SGGNAWRSDPRFSYLAARADIAAIAKNNAAGR MAV_2989|M.avium_104 FIWYGPRWAQAAT-----APSRLHKAFTTQGGIRVPGFITWPGFARQGQI : * . .: . : :. Mb3104|M.bovis_AF2122/97 RAIYLMTRDNVLEGDTGASLLSRQLGRIVNPPAPLRIKVPAHVAANFEGL Rv3077|M.tuberculosis_H37Rv RAIYLMTRDNVLEGDTGASLLSRQLGRIVNPPAPLRIKVPAHVAANFEGL MMAR_1577|M.marinum_M RAIYLMTRDNVLEGDTGASLLSRQLGRTVNPPAPLRIKLPAHVAANFEGL MUL_3457|M.ulcerans_Agy99 RAIYLMTRDNVLEGDTGASLLSRQLGRTVNPPAPLRIKLPAHVAANFEGL MSMEG_1286|M.smegmatis_MC2_155 RPIYLMTRDNVLEGDTGASGVARQLGRDVNPPAPLRIKVPAHVASNFEGL TH_0121|M.thermoresistible__bu RAVYLMTRDSVLDGDTGASGLARQLNLTANPPGPLRIRVPAHVASNFEGL Mflv_2372|M.gilvum_PYR-GCK RPVYLMTRDNVLEGDTGASGLARALRLTSRVPAPLRIRVPAHTAANFEGL Mvan_4274|M.vanbaalenii_PYR-1 RCVYLMTRDNVLEGDTGASGLARALKLTSKVPAPLRIRIPAHTAANFEGL MAB_4469c|M.abscessus_ATCC_199 KWIAHVTDDMSVEEMA-------TLLKDPRIRAVMGENAPTEIPTSAASH MAV_2989|M.avium_104 GTAFSTVMDIAPTLLELAGTSHPGTAYRGREVAPMRGRS---LVGYLSGA . * . . : . . Mb3104|M.bovis_AF2122/97 VVRVDDTDAAGGAGHLWKLVRTFDDPATWTEPGVRHLATN-GMGGDAYRT Rv3077|M.tuberculosis_H37Rv VVRVDDTDAAGGAGHLWKLVRTFDDPATWTEPGVRHLATN-GMGGDAYRT MMAR_1577|M.marinum_M VVRVEDSDAPGGAGHLWKLVRTFDDPATWTEPGVRHLASN-GVGGETYRT MUL_3457|M.ulcerans_Agy99 VVRVEDSDAPGGAGHLWKLVRTFDDPATWTEPGVRHLASN-GVGGETYRT MSMEG_1286|M.smegmatis_MC2_155 VVRVDDADAHGGAGHLWKLVRTFDDPSTWTEPGVRHLAAD-GLGGETYRS TH_0121|M.thermoresistible__bu VVCVEEATAAGGAGHLWKLVRTFDDPATWTEPGVRHLAAD-GLGGPAYRT Mflv_2372|M.gilvum_PYR-GCK VLRVPETSAAGGGGHLWKLVRSFDDPGTWTEPGVRQLAAD-GVGGPTYRS Mvan_4274|M.vanbaalenii_PYR-1 VIRVDEDAAPGGRGHLWKLVRSFDDPGTWTEPGVRHLAAD-GIGGPMYRT MAB_4469c|M.abscessus_ATCC_199 IVAVRTAEAKLANYSYWKPGGMRIDTSRPSEHEFYDYSTPSGKQESQNQA MAV_2989|M.avium_104 ADTVHDADTETG----WELFGRR--AIRQGNWKALHLPAPYGPGS----- * : . *: . : . .: * Mb3104|M.bovis_AF2122/97 DPLDDQWELYDLTADPIEAYNRWTDPQLHELRQHLRMLLKQQRAVSVPER Rv3077|M.tuberculosis_H37Rv DPLDDQWELYDLTADPIEAYNRWTDPQLHELRQHLRMLLKQQRAVSVPER MMAR_1577|M.marinum_M DPVDDQWELYDLTADPIETDNRWTDPELHELRQHLRMQLKQQRASSVPER MUL_3457|M.ulcerans_Agy99 DPVDDQWELYDLTADPIETDNRWTDPELHELRQHLRMQLKQQRASSVPER MSMEG_1286|M.smegmatis_MC2_155 DPLDDQWELYDLTADPVEAVNRWHYPDLHEVRQYLLAQLKQVRASSVPER TH_0121|M.thermoresistible__bu DPLDDQWELYDLTVDPIEAVNRWDDPGLDELRRHLRAQLKQARTVSVPER Mflv_2372|M.gilvum_PYR-GCK EPLDDQWELYDLTDDPIEQTNRWPDPALHALRAYLRTQLKHARAQSIPER Mvan_4274|M.vanbaalenii_PYR-1 DPLDDQWELYDLTDDPVEQHNRWTDPDLHELRAYLRAQLKSVRAESIPER MAB_4469c|M.abscessus_ATCC_199 GDSTKQAQLQALIDN----------EVLPEVQAPLPAFLGQAQEQGLADM MAV_2989|M.avium_104 ------WQLYDLASDPGE------VDDLAAARPDKLAELLALWDRYVEET :* * : * : * : : Mb3104|M.bovis_AF2122/97 NQPWPYAHRLPPSGASNGLVRRVLGRFVR Rv3077|M.tuberculosis_H37Rv NQPWPYAHRLPPSGASNGLVRRVLGRFVR MMAR_1577|M.marinum_M NQPWPYANRQPETGESQGPIRRLLGRIGS MUL_3457|M.ulcerans_Agy99 NQPWPYANRQPETGQSQGPIRRLLGRIGS MSMEG_1286|M.smegmatis_MC2_155 NVPWPYARR--------GGV--------- TH_0121|M.thermoresistible__bu NEPWPYVRRQAR----------------- Mflv_2372|M.gilvum_PYR-GCK NQPWPYARRQPPPARRWTPGRALRRLLG- Mvan_4274|M.vanbaalenii_PYR-1 NRPWPYVRRQPPQPARWSPGRALRRLRD- MAB_4469c|M.abscessus_ATCC_199 QKLMVLRGG-------------------- MAV_2989|M.avium_104 GVILDPISVFDAEL---------------