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MIPTEVDALLRAHQMFVGTGDHRMPDVHPQPGAEPLWRATPPNPATDQPRYRFRAARGREVLAAATRTDA VVAAVIADAHRDREQARELTGNVVNQARADGVAPPVTPLAQREAIRRRVGRLRAQRAHVLWAHRRARRRL AALRLLRYRMLHHHGSRQRLSPISGRAGIAGRAALSRLGRPYVWGVTGPDRFDCSGLVQWAYAQAGVHVD RTTYQQINDGIVVSRSQIRPGDLVFPHPGHVQLAIGNNPVVEAPHAGASVRISSLGSHVQIRRPL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0042 | - | - | 100% (275) | secreted protein P60-related protein |
| M. ulcerans Agy99 | MUL_3545 | - | 6e-15 | 36.73% (98) | hypothetical protein MUL_3545 |
| M. ulcerans Agy99 | MUL_1486 | - | 3e-13 | 36.11% (108) | cell wall-associated hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0024 | - | 8e-47 | 56.02% (191) | hypothetical protein Mb0024 |
| M. gilvum PYR-GCK | Mflv_2959 | - | 2e-17 | 40.74% (108) | NLP/P60 protein |
| M. tuberculosis H37Rv | Rv0024 | - | 1e-93 | 65.70% (277) | putative secreted protein P60-related protein |
| M. leprae Br4923 | MLBr_00885 | - | 1e-15 | 34.82% (112) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_1974 | - | 1e-16 | 41.51% (106) | hypothetical protein MAB_1974 |
| M. marinum M | MMAR_0043 | - | 1e-150 | 95.64% (275) | secreted protein P60-related protein |
| M. avium 104 | MAV_0042 | - | 7e-84 | 59.93% (272) | NLP/P60 family protein |
| M. smegmatis MC2 155 | MSMEG_4256 | - | 2e-17 | 41.84% (98) | NLP/P60 family protein |
| M. thermoresistible (build 8) | TH_3014 | - | 5e-17 | 40.37% (109) | PUTATIVE NLP/P60 family protein |
| M. vanbaalenii PYR-1 | Mvan_3552 | - | 3e-17 | 41.84% (98) | NLP/P60 protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2959|M.gilvum_PYR-GCK -----MTLDRAHWRIRRYRQTLIGVMTGLAVFGAVLTG--QAYADPAADA
Mvan_3552|M.vanbaalenii_PYR-1 -----MRLDRAHRSTRRTRQPLISAIAGLAVLGAVLTG--QAYADPAEDA
MSMEG_4256|M.smegmatis_MC2_155 -----MRHARAHRPTSRFKRPIAGAIASLALGAGLLAG--SVQADPADDA
TH_3014|M.thermoresistible__bu -----LRIDRAHRIIRSVHRPLIALIAGLTLLATGIAA--PGHADPADDA
MLBr_00885|M.leprae_Br4923 -----MRLGCKHPVVRLIAHFVVGTLVGFAVLSRFFVA--TAMADPAEDA
MAB_1974|M.abscessus_ATCC_1997 MSVGRLLRNHSDRLTPSPLRRAMLAVTAAALVGGVFTGAQTATADPNNDA
MUL_0042|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0043|M.marinum_M --------------------------------------------------
MAV_0042|M.avium_104 --------------------------------------------------
Mb0024|M.bovis_AF2122/97 --------------------------------------------------
Rv0024|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_2959|M.gilvum_PYR-GCK LAKMNELSRQAEQTTEAMHSAQLDLNSKLAIQQAAESKHAGDLAAVEAAR
Mvan_3552|M.vanbaalenii_PYR-1 LAKLNQLSRQAEQTTEAMHSAQLDLDNKLAIQQAADLKHASDAAAMESAK
MSMEG_4256|M.smegmatis_MC2_155 LAKLNELSRQAEQTTEAMHSAQLDLDNKLAAQQAAEKKHSEDAAAAEQAR
TH_3014|M.thermoresistible__bu LAKLQELSRQAEQTTEAMHSARLDLEEKLAAQRAAEEKAAADAAAADAAT
MLBr_00885|M.leprae_Br4923 LAKLNELSRQAEQTTEAVHSAQLDLTEKLAAQRAADKKYTDDQAALADAQ
MAB_1974|M.abscessus_ATCC_1997 VKKLNELSRQAEATSEAANTAKIDLDAKLAAQRDAEKTVLADEAVAKAAR
MUL_0042|M.ulcerans_Agy99 -----------------MIPTEVDALLRAHQMFVGTGDHRMPDVHPQPGA
MMAR_0043|M.marinum_M -----------------MIPTEVDALLRAHQMFVGTGDHRMPDVRPQPGA
MAV_0042|M.avium_104 -----------------MSHSELEALSRAHQLFAGGTRPASLDTGSGHYR
Mb0024|M.bovis_AF2122/97 -----------------MNYSEVELLSRAHQLFAGDSRRPGLDAGTTPYG
Rv0024|M.tuberculosis_H37Rv -----------------MNYSEVELLSRAHQLFAGDSRRPGLDAGTTPYG
:.:: : . .
Mflv_2959|M.gilvum_PYR-GCK HRLADYQGKVDKLAAAQYMGGRASGFDAMLTASSPQSLIDQMSVQRVMAT
Mvan_3552|M.vanbaalenii_PYR-1 AQLSDFQSKVDHLAAAQYMGGRPSGFDAMLTASSPQGLIDQLSVQRVMAT
MSMEG_4256|M.smegmatis_MC2_155 AQLATFQASVNRVAAAQYMGGRTSGVDAILTADSPQQLIDQLAVQRVMAT
TH_3014|M.thermoresistible__bu AQLANYQTAVDKLAASQYMGGRTDGFNAILTARSPQQLIDQLAVQRVMAT
MLBr_00885|M.leprae_Br4923 VRLATFQAAVNKLAAATYMSGRINGMTALLTAYSPQQLINKLALQRVLGV
MAB_1974|M.abscessus_ATCC_1997 MAVSTYQVDVNKAMVAAYMGGTTSGYGAVLTSNSPQNLIDQLSVQRTVGG
MUL_0042|M.ulcerans_Agy99 EPLWRATPPNPATDQPRYRFRAARGREVLAAATR-----TDAVVAAVIAD
MMAR_0043|M.marinum_M EPLRRATLPNPATDQPRYGFRAARGREVLAAATR-----TDAAVAAVIAD
MAV_0042|M.avium_104 DLLGRAARLSDGFAHGGYRLAVQHSRQRLASTSD-----TDAAVTDLLAG
Mb0024|M.bovis_AF2122/97 DLLSRAADLNVGAGQRRYQLAVDHSRAALLSAAR-----TDAAAGAVITG
Rv0024|M.tuberculosis_H37Rv DLLSRAADLNVGAGQRRYQLAVDHSRAALLSAAR-----TDAAAGAVITG
: * . : :: . :
Mflv_2959|M.gilvum_PYR-GCK EMQSQMAAFRDAGTQAEIAEQASAASATEAKTAAEQAAAVRADLQSKQSQ
Mvan_3552|M.vanbaalenii_PYR-1 EMQAQMTSFREAGRQAEVAEQASAASAAEAKTAAEQAAAVRADLQSKQSQ
MSMEG_4256|M.smegmatis_MC2_155 EMATQMQNFRSVGEKAAAAEQASAKSAAEAKTAAEQAAAVRAELQSKQSQ
TH_3014|M.thermoresistible__bu EMSEQMHRFRLAQEEAAKAAEASAKSAAEARTAAEQAAAVRAELQAKQSE
MLBr_00885|M.leprae_Br4923 QMATQMAGYRDAGEQAVKAEQTSAKSAADAKHAADQAAVVRAGLQSKQSK
MAB_1974|M.abscessus_ATCC_1997 EMRSRMDSYRAAQTSADEAEQRSRDAAEAARVAAEQAKNVRASLQAKQSQ
MUL_0042|M.ulcerans_Agy99 AHRDREQARELTGNVVNQARADGVAPPVTPLAQREAIRRRVGRLRAQRAH
MMAR_0043|M.marinum_M AHRDREQARELTGNVVNQARADGVAPPVTPLAQREAIRRRVGRLRAQRAH
MAV_0042|M.avium_104 AHRDRAQARELTGAVLDAGRADAAANPTTPLAQREAMRRRVMRLRTQHAH
Mb0024|M.bovis_AF2122/97 AQRDRAWARRSTGTVLDEARSDTTVTAVMPIAQREAIRRRVARLRAQRAH
Rv0024|M.tuberculosis_H37Rv AQRDRAWARRSTGTVLDEARSDTTVTAVMPIAQREAIRRRVARLRAQRAH
: . . . . . : *:::::.
Mflv_2959|M.gilvum_PYR-GCK LQTQIAIVKAQYEALTPTQRETLAAAPPPPPVP-AALPVPPAPGQ-DPAI
Mvan_3552|M.vanbaalenii_PYR-1 LQVQIAVVKSQYEALTPQQRDVLAAAPPPPPVP-AAAPVPPPPGQ-DPAV
MSMEG_4256|M.smegmatis_MC2_155 LQVQIAIVKSQYEALTPQQREALATAPPPPAAPPAPAPDALPPAN-DPGV
TH_3014|M.thermoresistible__bu LQQQIEVVKAQYEALTPDQREALAAMPPVPPGT----PTGELPGQHDTEV
MLBr_00885|M.leprae_Br4923 LQLQIAVVKSHYLSLSPRQRTTLAEPGPVPAVA-------TLPGAASAGV
MAB_1974|M.abscessus_ATCC_1997 LQVQIAVVKSQYNTLSPGQRAQLAAPAPVPPPP------AAEPGE--AGD
MUL_0042|M.ulcerans_Agy99 VLWAHRRARRRLAALRLLRYRMLHHHGSRQ----------RLSPI-----
MMAR_0043|M.marinum_M VLWAHRRARRRLAALRLLRYRMLHHHGSRQ----------RLSPI-----
MAV_0042|M.avium_104 VVSAAARARHHHARLLALRYRLRHGVGLAG----------LRGPG-----
Mb0024|M.bovis_AF2122/97 VLTARRRARRHLAALRALRYRVAHGPGVALAKL-------RLPSP-----
Rv0024|M.tuberculosis_H37Rv VLTARRRARRHLAALRALRYRVAHGPGVALAKL-------RLPSP-----
: .: : * :
Mflv_2959|M.gilvum_PYR-GCK LAAPPAPPVPGAIPPGDIAPPG--SPAATTVIQAALSRIGSPYSWGGSGP
Mvan_3552|M.vanbaalenii_PYR-1 LAAPPAPPALGAIPPGDIAPPG--SPVSSTVIQAALSRIGSPYSWGGSGP
MSMEG_4256|M.smegmatis_MC2_155 LAAPPEGIPPGDIAPPDAAIPGGPSPVSNTVIQAALSRIGSPYSWGGSGP
TH_3014|M.thermoresistible__bu LAAP--GIPPGDLAP-EAAVPGGPSNDRATVVQAALSRIGSPYSWGGSGP
MLBr_00885|M.leprae_Br4923 SPPPDAAPPGGLLGVAPAPFAG--GGDRAAVVQAALTQIGSPYAWGGAAP
MAB_1974|M.abscessus_ATCC_1997 APEPLMQAAAAAPAP-EAAIGGGGSPAGAGAVAAALTRIGAPYSWGGSGP
MUL_0042|M.ulcerans_Agy99 ------------------------SGRAGIAGRAALSRLGRPYVWGVTGP
MMAR_0043|M.marinum_M ------------------------SGRAGIAVRAALSRLGRPYVWGATGP
MAV_0042|M.avium_104 ------------------------SDRAALAVRAALSRLGRPYVWGATGP
Mb0024|M.bovis_AF2122/97 ------------------------SGRAGIAVHAALSRLGRPYVWGATGP
Rv0024|M.tuberculosis_H37Rv ------------------------SGRAGIAVHAALSRLGRPYVWGATGP
. . ***:::* ** ** :.*
Mflv_2959|M.gilvum_PYR-GCK GAFDCSGLVMWSFQQ-AGIALPHSSQALARGGQPVSTD-QMQPGDLVTYY
Mvan_3552|M.vanbaalenii_PYR-1 GAFDCSGLVMWSFQQ-AGISLPHSSQALARGGQPVSMD-QMQPGDLVTYY
MSMEG_4256|M.smegmatis_MC2_155 NAFDCSGLVMWSFQQ-AGISLPHSSQALARGGQPVSMD-NIQPGDLVTYY
TH_3014|M.thermoresistible__bu NAFDCSGLVMWAFRQGAGINLPHSSQALARGGQPVSMA-DIQPGDVVTYY
MLBr_00885|M.leprae_Br4923 GGFDCSGLVMWAYQQ-AGIALPHSSQALARGGQPVSLS-ELQPGDVLTFY
MAB_1974|M.abscessus_ATCC_1997 NAFDCSGLVMWAYGQ-QGVSLPHSSQALARGGTPVSLS-ELQPGDVINFY
MUL_0042|M.ulcerans_Agy99 DRFDCSGLVQWAYAQ-AGVHVDRTTYQQINDGIVVSRS-QIRPGDLV--F
MMAR_0043|M.marinum_M DRFDCSGLVQWAYAQ-AGVHLDRTTYQQINDGIVVSRS-HIRPGDLV--F
MAV_0042|M.avium_104 DQFDCSGLVQWSYAQ-AGIHLDRTTYQQINEGIPVPRS-QVRPGDLV--F
Mb0024|M.bovis_AF2122/97 ---TSSTVPVWSSGP-TPRRVFTWIAPPINRSTRGSRCRAHRSGRAI--W
Rv0024|M.tuberculosis_H37Rv NQFDCSGLVQWAYAQ-AGVHLDRTTYQQINEGIPVPRS-QVRPGDLV--F
.* : *: : . . . :.* : :
Mflv_2959|M.gilvum_PYR-GCK SDASHVGIYIGDGMMVHASTYGTPVRVAPVNN-APIYNVRRY-
Mvan_3552|M.vanbaalenii_PYR-1 SDASHVGIYIGDGMMVHASTYGTPVRVAPVNN-APIHNVRRY-
MSMEG_4256|M.smegmatis_MC2_155 SDASHVGIYIGDGMMVHASTYGSPVRVAPVNN-APIYNVRRY-
TH_3014|M.thermoresistible__bu SDASHAAIYIGNGMMVHASTYGTPVRVAPVNN-APIYNIRRY-
MLBr_00885|M.leprae_Br4923 SDASHAGIYVGDGMMIHSSTYGVPVRVVPMNSSGPIYDARRY-
MAB_1974|M.abscessus_ATCC_1997 GDASHTGIYVGNGMMVHASTYGVPVAVVPITSSGPIYNARRY-
MUL_0042|M.ulcerans_Agy99 PHPGHVQLAIGNNPVVEAPHAGASVRISSLGSHVQIRRPL---
MMAR_0043|M.marinum_M PHPGHVQLAIGNNLVVEAPHAGASVRISPLGNHVQIRRPL---
MAV_0042|M.avium_104 PHAGHVQLAIGNNLVVEAPYSGASVRISRLGNNVAIRRPI---
Mb0024|M.bovis_AF2122/97 SSRTPGTCSWRSATIWSSRRPMRARRFGSARWATTCR--FGDR
Rv0024|M.tuberculosis_H37Rv PHPGHVQLAIGNNLVVEAPHAGASVRVSSLGNNVQIRRPLSGR
. : : . .