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VNYSEVELLSRAHQLFAGDSRRPGLDAGTTPYGDLLSRAADLNVGAGQRRYQLAVDHSRAALLSAARTDA AAGAVITGAQRDRAWARRSTGTVLDEARSDTTVTAVMPIAQREAIRRRVARLRAQRAHVLTARRRARRHL AALRALRYRVAHGPGVALAKLRLPSPSGRAGIAVHAALSRLGRPYVWGATGPNQFDCSGLVQWAYAQAGV HLDRTTYQQINEGIPVPRSQVRPGDLVFPHPGHVQLAIGNNLVVEAPHAGASVRVSSLGNNVQIRRPLSG R
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0024 | - | - | 100% (281) | PUTATIVE SECRETED PROTEIN P60-RELATED PROTEIN |
| M. tuberculosis H37Rv | Rv2190c | - | 2e-17 | 38.52% (122) | hypothetical protein Rv2190c |
| M. tuberculosis H37Rv | Rv3896c | - | 3e-16 | 35.36% (181) | hypothetical protein Rv3896c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0024 | - | 1e-104 | 100.00% (192) | hypothetical protein Mb0024 |
| M. gilvum PYR-GCK | Mflv_0888 | - | 7e-22 | 29.96% (257) | NLP/P60 protein |
| M. leprae Br4923 | MLBr_00885 | - | 7e-19 | 29.65% (199) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_1974 | - | 2e-20 | 33.33% (219) | hypothetical protein MAB_1974 |
| M. marinum M | MMAR_0043 | - | 2e-95 | 67.15% (277) | secreted protein P60-related protein |
| M. avium 104 | MAV_0042 | - | 1e-101 | 68.35% (278) | NLP/P60 family protein |
| M. smegmatis MC2 155 | MSMEG_4256 | - | 5e-21 | 42.99% (107) | NLP/P60 family protein |
| M. thermoresistible (build 8) | TH_3014 | - | 1e-20 | 41.32% (121) | PUTATIVE NLP/P60 family protein |
| M. ulcerans Agy99 | MUL_0042 | - | 1e-93 | 65.70% (277) | secreted protein P60-related protein |
| M. vanbaalenii PYR-1 | Mvan_3713 | - | 4e-21 | 29.49% (295) | NLP/P60 protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4256|M.smegmatis_MC2_155 ------MRHARAHRPTSRFKRPIAGAIASLALGAGLL-AGSVQADPADDA
TH_3014|M.thermoresistible__bu ------LRIDRAHRIIRSVHRPLIALIAGLTLLATGI-AAPGHADPADDA
MLBr_00885|M.leprae_Br4923 ------MRLGCKHPVVRLIAHFVVGTLVGFAVLSRFF-VATAMADPAEDA
Mflv_0888|M.gilvum_PYR-GCK ------MNSLALCHRFRVIARRALCALLGASLLFAFV-AIDVGADPAADA
Mvan_3713|M.vanbaalenii_PYR-1 -------------------MAIVLALTLGNSAGIG-------WADPAADA
MAB_1974|M.abscessus_ATCC_1997 MSVGRLLRNHSDRLTPSPLRRAMLAVTAAALVGGVFTGAQTATADPNNDA
Rv0024|M.tuberculosis_H37Rv ------------------------------------------------MN
Mb0024|M.bovis_AF2122/97 ------------------------------------------------MN
MMAR_0043|M.marinum_M ------------------------------------------------MI
MUL_0042|M.ulcerans_Agy99 ------------------------------------------------MI
MAV_0042|M.avium_104 ------------------------------------------------MS
MSMEG_4256|M.smegmatis_MC2_155 LAKLNELSRQAEQTTEAMHSAQLDLDNKLAAQQAAEKKHSEDAAAAEQAR
TH_3014|M.thermoresistible__bu LAKLQELSRQAEQTTEAMHSARLDLEEKLAAQRAAEEKAAADAAAADAAT
MLBr_00885|M.leprae_Br4923 LAKLNELSRQAEQTTEAVHSAQLDLTEKLAAQRAADKKYTDDQAALADAQ
Mflv_0888|M.gilvum_PYR-GCK LAELTEQSRLAEQTTEQIHTAQIDLDERLAAQQVAEKKAASDRVRVDAAS
Mvan_3713|M.vanbaalenii_PYR-1 LARLTELSREAEQTTEAVYSAELDLEAKLAAQRRAEDRQRAELEAMTAAR
MAB_1974|M.abscessus_ATCC_1997 VKKLNELSRQAEATSEAANTAKIDLDAKLAAQRDAEKTVLADEAVAKAAR
Rv0024|M.tuberculosis_H37Rv YSEVELLSRAHQLFAGDSRRPGLDAGTTPYGDLLSR-------AADLNVG
Mb0024|M.bovis_AF2122/97 YSEVELLSRAHQLFAGDSRRPGLDAGTTPYGDLLSR-------AADLNVG
MMAR_0043|M.marinum_M PTEVDALLRAHQMFVGTGDHRMPDVRPQPGAEPLRR-------ATLPNPA
MUL_0042|M.ulcerans_Agy99 PTEVDALLRAHQMFVGTGDHRMPDVHPQPGAEPLWR-------ATPPNPA
MAV_0042|M.avium_104 HSELEALSRAHQLFAGGTRPASLDTGSGHYRDLLGR-------AARLSDG
.: * : * :
MSMEG_4256|M.smegmatis_MC2_155 AQLATFQASVNRVAAAQYMGGRTSGVDAILTADSPQQLIDQLAVQRVMAT
TH_3014|M.thermoresistible__bu AQLANYQTAVDKLAASQYMGGRTDGFNAILTARSPQQLIDQLAVQRVMAT
MLBr_00885|M.leprae_Br4923 VRLATFQAAVNKLAAATYMSGRINGMTALLTAYSPQQLINKLALQRVLGV
Mflv_0888|M.gilvum_PYR-GCK ADLAKYQAAVDKLAAAAYMGGRTDTLAAALTATSPQELIDQLAIQKTVAS
Mvan_3713|M.vanbaalenii_PYR-1 ADLGEYQAAVNQVAAASYMGGSTSTISAALTAESPQRLLDELSSSRVMAT
MAB_1974|M.abscessus_ATCC_1997 MAVSTYQVDVNKAMVAAYMGGTTSGYGAVLTSNSPQNLIDQLSVQRTVGG
Rv0024|M.tuberculosis_H37Rv AGQRRYQLAVDHSRAALLSAARTDAAAGAVITGAQR--------DRAWAR
Mb0024|M.bovis_AF2122/97 AGQRRYQLAVDHSRAALLSAARTDAAAGAVITGAQR--------DRAWAR
MMAR_0043|M.marinum_M TDQPRYGFRAARGREVLAAATRTDAAVAAVIADAHR--------DREQAR
MUL_0042|M.ulcerans_Agy99 TDQPRYRFRAARGREVLAAATRTDAVVAAVIADAHR--------DREQAR
MAV_0042|M.avium_104 FAHGGYRLAVQHSRQRLASTSDTDAAVTDLLAGAHR--------DRAQAR
: . : . : : : : .: .
MSMEG_4256|M.smegmatis_MC2_155 EMATQMQNFRSVGEKAAAAEQASAKSAAEAKTAAEQAAAVRAELQSKQSQ
TH_3014|M.thermoresistible__bu EMSEQMHRFRLAQEEAAKAAEASAKSAAEARTAAEQAAAVRAELQAKQSE
MLBr_00885|M.leprae_Br4923 QMATQMAGYRDAGEQAVKAEQTSAKSAADAKHAADQAAVVRAGLQSKQSK
Mflv_0888|M.gilvum_PYR-GCK ELTVQMAAFRSASARAATAADQSAMSAAQARGAADEAAAVRTDLEAKQRR
Mvan_3713|M.vanbaalenii_PYR-1 QMSDRIKAFRAASTRADDAARAAQSSALAARTAAEQASAVRASLQSKQSR
MAB_1974|M.abscessus_ATCC_1997 EMRSRMDSYRAAQTSADEAEQRSRDAAEAARVAAEQAKNVRASLQAKQSQ
Rv0024|M.tuberculosis_H37Rv RSTGTVLDEARSDTTVTAVMPIAQREAIRRR--VARLRAQRAHVLTARRR
Mb0024|M.bovis_AF2122/97 RSTGTVLDEARSDTTVTAVMPIAQREAIRRR--VARLRAQRAHVLTARRR
MMAR_0043|M.marinum_M ELTGNVVNQARADGVAPPVTPLAQREAIRRR--VGRLRAQRAHVLWAHRR
MUL_0042|M.ulcerans_Agy99 ELTGNVVNQARADGVAPPVTPLAQREAIRRR--VGRLRAQRAHVLWAHRR
MAV_0042|M.avium_104 ELTGAVLDAGRADAAANPTTPLAQREAMRRR--VMRLRTQHAHVVSAAAR
. : . . : * : . . :: : .
MSMEG_4256|M.smegmatis_MC2_155 LQVQIAIVKSQYEALTPQQREALATAPPPPAAPPAPAPDALPPANDPGVL
TH_3014|M.thermoresistible__bu LQQQIEVVKAQYEALTPDQREALAAMPP---VPPGTPTGELPGQHDTEVL
MLBr_00885|M.leprae_Br4923 LQLQIAVVKSHYLSLSPRQRTTLAEPGP------VPAVATLPGAASAGVS
Mflv_0888|M.gilvum_PYR-GCK MQEQIAVVQARYEALTTGQRAILADPGPP-----PPPLPPSSPANDPSIV
Mvan_3713|M.vanbaalenii_PYR-1 LRTQIAEVEALYRALTPDQRAALADPGP------VPPAPPVPPAANPAIM
MAB_1974|M.abscessus_ATCC_1997 LQVQIAVVKSQYNTLSPGQRAQLAAPAPVP----PPPAAEPGEAGDAPEP
Rv0024|M.tuberculosis_H37Rv ARRHLAALRALRYRVAHGPGVALA-------------KLRLPSPSGR---
Mb0024|M.bovis_AF2122/97 ARRHLAALRALRYRVAHGPGVALA-------------KLRLPSPSGR---
MMAR_0043|M.marinum_M ARRRLAALRLLRYRMLHHHGSRQ----------------RLSPISGR---
MUL_0042|M.ulcerans_Agy99 ARRRLAALRLLRYRMLHHHGSRQ----------------RLSPISGR---
MAV_0042|M.avium_104 ARHHHARLLALRYRLRHGVGLAG----------------LRGPGSDR---
: : : : .
MSMEG_4256|M.smegmatis_MC2_155 AAPPEGIPPGDIAPPDAAIPGGPSPVSNTVIQAALSRIGSPYSWGGSGPN
TH_3014|M.thermoresistible__bu AAP--GIPPGDLAP-EAAVPGGPSNDRATVVQAALSRIGSPYSWGGSGPN
MLBr_00885|M.leprae_Br4923 PPP-DAAPPGGLLG-VAPAPFAGGGDRAAVVQAALTQIGSPYAWGGAAPG
Mflv_0888|M.gilvum_PYR-GCK AMPG--PAVG-------GSPGG----ATAVVQAALTRVGSPYSWGATGPD
Mvan_3713|M.vanbaalenii_PYR-1 AMPEAIPPVG-------PGPSSS-PEGAAVVQAALTRVGAPYSWGATGPD
MAB_1974|M.abscessus_ATCC_1997 LMQAAAAAPAP----EAAIGGGGSPAGAGAVAAALTRIGAPYSWGGSGPN
Rv0024|M.tuberculosis_H37Rv --------------------------AGIAVHAALSRLGRPYVWGATGPN
Mb0024|M.bovis_AF2122/97 --------------------------AGIAVHAALSRLGRPYVWGATGP-
MMAR_0043|M.marinum_M --------------------------AGIAVRAALSRLGRPYVWGATGPD
MUL_0042|M.ulcerans_Agy99 --------------------------AGIAGRAALSRLGRPYVWGVTGPD
MAV_0042|M.avium_104 --------------------------AALAVRAALSRLGRPYVWGATGPD
. ***:::* ** ** :.*
MSMEG_4256|M.smegmatis_MC2_155 AFDCSGLVMWSFQQ-AGISLPHSSQALARGGQPVSMD-NIQPGDLVTYYS
TH_3014|M.thermoresistible__bu AFDCSGLVMWAFRQGAGINLPHSSQALARGGQPVSMA-DIQPGDVVTYYS
MLBr_00885|M.leprae_Br4923 GFDCSGLVMWAYQQ-AGIALPHSSQALARGGQPVSLS-ELQPGDVLTFYS
Mflv_0888|M.gilvum_PYR-GCK AFDCSGLIKWAFLQ-NGKSLPRSSQALAQGGQPVATS-DLQPGDIVTFYD
Mvan_3713|M.vanbaalenii_PYR-1 AFDCSGLIKWAFLQ-NGKSLPRSSQALAAGGQPVATT-EVQPGDIVTFYS
MAB_1974|M.abscessus_ATCC_1997 AFDCSGLVMWAYGQ-QGVSLPHSSQALARGGTPVSLS-ELQPGDVINFYG
Rv0024|M.tuberculosis_H37Rv QFDCSGLVQWAYAQ-AGVHLDRTTYQQINEGIPVPRS-QVRPGDLV--FP
Mb0024|M.bovis_AF2122/97 --TSSTVPVWSSGP-TPRRVFTWIAPPINRSTRGSRCRAHRSGRAI--WS
MMAR_0043|M.marinum_M RFDCSGLVQWAYAQ-AGVHLDRTTYQQINDGIVVSRS-HIRPGDLV--FP
MUL_0042|M.ulcerans_Agy99 RFDCSGLVQWAYAQ-AGVHVDRTTYQQINDGIVVSRS-QIRPGDLV--FP
MAV_0042|M.avium_104 QFDCSGLVQWSYAQ-AGIHLDRTTYQQINEGIPVPRS-QVRPGDLV--FP
.* : *: : . . :.* : :
MSMEG_4256|M.smegmatis_MC2_155 DASHVGIYIGDGMMVHASTYGSPVRVAPVNN-APIYNVRRY-
TH_3014|M.thermoresistible__bu DASHAAIYIGNGMMVHASTYGTPVRVAPVNN-APIYNIRRY-
MLBr_00885|M.leprae_Br4923 DASHAGIYVGDGMMIHSSTYGVPVRVVPMNSSGPIYDARRY-
Mflv_0888|M.gilvum_PYR-GCK DISHAGIYIGEGMMVHASTYGTPVKVAPISS-APIHNVRRY-
Mvan_3713|M.vanbaalenii_PYR-1 DASHAGIYIGDGNMVHASTYGTPVKVAPISS-APIYNVRRY-
MAB_1974|M.abscessus_ATCC_1997 DASHTGIYVGNGMMVHASTYGVPVAVVPITSSGPIYNARRY-
Rv0024|M.tuberculosis_H37Rv HPGHVQLAIGNNLVVEAPHAGASVRVSSLGNNVQIRRPLSGR
Mb0024|M.bovis_AF2122/97 SRTPGTCSWRSATIWSSRRPMRARRFGSARWATTCR--FGDR
MMAR_0043|M.marinum_M HPGHVQLAIGNNLVVEAPHAGASVRISPLGNHVQIRRPL---
MUL_0042|M.ulcerans_Agy99 HPGHVQLAIGNNPVVEAPHAGASVRISSLGSHVQIRRPL---
MAV_0042|M.avium_104 HAGHVQLAIGNNLVVEAPYSGASVRISRLGNNVAIRRPI---
. : : . .