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RLDCRQLTARVIRRSAIGSLASFTALSGFVAAGAMADQAEDALAKLNELSRQAEQTTEAMHSAELELGAK LAAQQAAENKLTDDQAALDATKGQLASFQTAVNKVAAAAYMGGRANGMDTILTAPSPQLLIDGLSMQRVM VHQMATQMSGFRTAREQTAKAEQASEKSAADAKSAAEQAAAVRANLQHKQSQLQVQIAVVKSQYLALTPD QRTALVDPGQVPAGLPGAPGPAPEGTPPGGPPPAGAPVPGEAPPPGAGGVSAMPFTPPDGAGGDRAAVVQ AALTQVGTPYAWGGAAPGGFDCSGLVMWAFQQAGIALPHSSQALAHEGQPVSLSDLQPGDVLTFYSDASH AGIYIGDGLMVHSSTYGVPVRVVPMNSSGPIYDARRY*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3545 | - | - | 100% (388) | hypothetical protein MUL_3545 |
| M. ulcerans Agy99 | MUL_1486 | - | 6e-31 | 27.59% (464) | cell wall-associated hydrolase |
| M. ulcerans Agy99 | MUL_0042 | - | 1e-14 | 36.73% (98) | secreted protein P60-related protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2213c | - | 1e-169 | 78.35% (388) | hypothetical protein Mb2213c |
| M. gilvum PYR-GCK | Mflv_2959 | - | 1e-117 | 56.85% (394) | NLP/P60 protein |
| M. tuberculosis H37Rv | Rv2190c | - | 1e-169 | 78.35% (388) | hypothetical protein Rv2190c |
| M. leprae Br4923 | MLBr_00885 | - | 1e-143 | 68.56% (388) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_1974 | - | 1e-100 | 52.43% (391) | hypothetical protein MAB_1974 |
| M. marinum M | MMAR_3234 | - | 0.0 | 97.68% (388) | hypothetical protein MMAR_3234 |
| M. avium 104 | MAV_2304 | - | 1e-143 | 76.14% (352) | NLP/P60 family protein |
| M. smegmatis MC2 155 | MSMEG_4256 | - | 1e-123 | 61.07% (375) | NLP/P60 family protein |
| M. thermoresistible (build 8) | TH_3014 | - | 1e-117 | 59.38% (389) | PUTATIVE NLP/P60 family protein |
| M. vanbaalenii PYR-1 | Mvan_3552 | - | 1e-118 | 57.87% (394) | NLP/P60 protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2959|M.gilvum_PYR-GCK ------MTLDRAHWRIRRYRQTLIGVMTGLAVFGAVLTGQ-AYADPAADA
Mvan_3552|M.vanbaalenii_PYR-1 ------MRLDRAHRSTRRTRQPLISAIAGLAVLGAVLTGQ-AYADPAEDA
MSMEG_4256|M.smegmatis_MC2_155 ------MRHARAHRPTSRFKRPIAGAIASLALGAGLLAGS-VQADPADDA
TH_3014|M.thermoresistible__bu ------LRIDRAHRIIRSVHRPLIALIAGLTLLATGIAAP-GHADPADDA
MUL_3545|M.ulcerans_Agy99 ------MRLDCRQLTARVIRRSAIGSLASFTALSGFVAAG-AMADQAEDA
MMAR_3234|M.marinum_M ------MRLDCRQLTARVIRRSAIGSLASFTALSGFVAAG-AMADPAEDA
Mb2213c|M.bovis_AF2122/97 ------MRLDQRWLIARVIMRSAIGFFASFTVSSGVLAAN-VLADPADDA
Rv2190c|M.tuberculosis_H37Rv ------MRLDQRWLIARVIMRSAIGFFASFTVSSGVLAAN-VLADPADDA
MAV_2304|M.avium_104 --------------------------------------------------
MLBr_00885|M.leprae_Br4923 ------MRLGCKHPVVRLIAHFVVGTLVGFAVLSRFFVAT-AMADPAEDA
MAB_1974|M.abscessus_ATCC_1997 MSVGRLLRNHSDRLTPSPLRRAMLAVTAAALVGGVFTGAQTATADPNNDA
Mflv_2959|M.gilvum_PYR-GCK LAKMNELSRQAEQTTEAMHSAQLDLNSKLAIQQAAESKHAGDLAAVEAAR
Mvan_3552|M.vanbaalenii_PYR-1 LAKLNQLSRQAEQTTEAMHSAQLDLDNKLAIQQAADLKHASDAAAMESAK
MSMEG_4256|M.smegmatis_MC2_155 LAKLNELSRQAEQTTEAMHSAQLDLDNKLAAQQAAEKKHSEDAAAAEQAR
TH_3014|M.thermoresistible__bu LAKLQELSRQAEQTTEAMHSARLDLEEKLAAQRAAEEKAAADAAAADAAT
MUL_3545|M.ulcerans_Agy99 LAKLNELSRQAEQTTEAMHSAELELGAKLAAQQAAENKLTDDQAALDATK
MMAR_3234|M.marinum_M LAKLNELSRQAEQTTEAMHSAELDLGAKLAAQQAAENKLTDDQAALDAAK
Mb2213c|M.bovis_AF2122/97 LAKLNELSRQAEQTTEALHSAQLDLNEKLAAQRAADQKLADNRTALDAAR
Rv2190c|M.tuberculosis_H37Rv LAKLNELSRQAEQTTEALHSAQLDLNEKLAAQRAADQKLADNRTALDAAR
MAV_2304|M.avium_104 MAKLNELSRQAEQTTEAMHSAQLDLNEKLAAQRAAEKKHDDDQAAVDAAK
MLBr_00885|M.leprae_Br4923 LAKLNELSRQAEQTTEAVHSAQLDLTEKLAAQRAADKKYTDDQAALADAQ
MAB_1974|M.abscessus_ATCC_1997 VKKLNELSRQAEATSEAANTAKIDLDAKLAAQRDAEKTVLADEAVAKAAR
: *:::****** *:** ::*.::* *** *: *: . : :. :
Mflv_2959|M.gilvum_PYR-GCK HRLADYQGKVDKLAAAQYMGGRASGFDAMLTASSPQSLIDQMSVQRVMAT
Mvan_3552|M.vanbaalenii_PYR-1 AQLSDFQSKVDHLAAAQYMGGRPSGFDAMLTASSPQGLIDQLSVQRVMAT
MSMEG_4256|M.smegmatis_MC2_155 AQLATFQASVNRVAAAQYMGGRTSGVDAILTADSPQQLIDQLAVQRVMAT
TH_3014|M.thermoresistible__bu AQLANYQTAVDKLAASQYMGGRTDGFNAILTARSPQQLIDQLAVQRVMAT
MUL_3545|M.ulcerans_Agy99 GQLASFQTAVNKVAAAAYMGGRANGMDTILTAPSPQLLIDGLSMQRVMVH
MMAR_3234|M.marinum_M GQLASFQTAVNKVAAAAYMGGRANGMDTILTAPSPQLLIDGLSMQRVMAH
Mb2213c|M.bovis_AF2122/97 ARLATFQTAVNKVAAATYMGGRTHGMDAILTAESPQLLIDRLSVQRVMAH
Rv2190c|M.tuberculosis_H37Rv ARLATFQTAVNKVAAATYMGGRTHGMDAILTAESPQLLIDRLSVQRVMAH
MAV_2304|M.avium_104 AHLASYQNAVNNLAAATYMGGRVDGMEAILTAGSPQGLIDKLAVQRLMAT
MLBr_00885|M.leprae_Br4923 VRLATFQAAVNKLAAATYMSGRINGMTALLTAYSPQQLINKLALQRVLGV
MAB_1974|M.abscessus_ATCC_1997 MAVSTYQVDVNKAMVAAYMGGTTSGYGAVLTSNSPQNLIDQLSVQRTVGG
:: :* *:. .: **.* * ::**: *** **: :::** :
Mflv_2959|M.gilvum_PYR-GCK EMQSQMAAFRDAGTQAEIAEQASAASATEAKTAAEQAAAVRADLQSKQSQ
Mvan_3552|M.vanbaalenii_PYR-1 EMQAQMTSFREAGRQAEVAEQASAASAAEAKTAAEQAAAVRADLQSKQSQ
MSMEG_4256|M.smegmatis_MC2_155 EMATQMQNFRSVGEKAAAAEQASAKSAAEAKTAAEQAAAVRAELQSKQSQ
TH_3014|M.thermoresistible__bu EMSEQMHRFRLAQEEAAKAAEASAKSAAEARTAAEQAAAVRAELQAKQSE
MUL_3545|M.ulcerans_Agy99 QMATQMSGFRTAREQTAKAEQASEKSAADAKSAAEQAAAVRANLQHKQSQ
MMAR_3234|M.marinum_M QMATQMSGFRTAREQAAKAEQASEKSAADAKSAAEQAAAVRANLQHKQSQ
Mb2213c|M.bovis_AF2122/97 QMSTQMARFKAAGEQAVKAEQAAAKSAADARSAAEQAAAVRANLQHKQSQ
Rv2190c|M.tuberculosis_H37Rv QMSTQMARFKAAGEQAVKAEQAAAKSAADARSAAEQAAAVRANLQHKQSQ
MAV_2304|M.avium_104 QMASQMKSYRIAGEQAAKAERESAKSAADAKSAAEQAAAVRASLQSKQSQ
MLBr_00885|M.leprae_Br4923 QMATQMAGYRDAGEQAVKAEQTSAKSAADAKHAADQAAVVRAGLQSKQSK
MAB_1974|M.abscessus_ATCC_1997 EMRSRMDSYRAAQTSADEAEQRSRDAAEAARVAAEQAKNVRASLQAKQSQ
:* :* :: . .: * . : :* *: **:** *** ** ***:
Mflv_2959|M.gilvum_PYR-GCK LQTQIAIVKAQYEALTPTQRETLAAAPPPPPVP-----AALPVPPAPGQ-
Mvan_3552|M.vanbaalenii_PYR-1 LQVQIAVVKSQYEALTPQQRDVLAAAPPPPPVP-----AAAPVPPPPGQ-
MSMEG_4256|M.smegmatis_MC2_155 LQVQIAIVKSQYEALTPQQREALATAPPPPAAPP----APAPDALPPAN-
TH_3014|M.thermoresistible__bu LQQQIEVVKAQYEALTPDQREALAAMPPVPPGT--------PTGELPGQH
MUL_3545|M.ulcerans_Agy99 LQVQIAVVKSQYLALTPDQRTALVDPGQVPAGLPGAPG-PAPEGTPPGGP
MMAR_3234|M.marinum_M LQVQIAVVKSQYLALTPDQRTALADPGQVPAGLPGAPG-PAPEGTPPGGP
Mb2213c|M.bovis_AF2122/97 LQVQIAVVKSQYVALTPEERTALADPGPVPAVAAIAPG-APPAALPPG-A
Rv2190c|M.tuberculosis_H37Rv LQVQIAVVKSQYVALTPEERTALADPGPVPAVAAIAPG-APPAALPPG-A
MAV_2304|M.avium_104 LQVQIAVVKSQYMSLTADQRTALANPGPAVPAAATAPGAPAPEAAPPG--
MLBr_00885|M.leprae_Br4923 LQLQIAVVKSHYLSLSPRQRTTLAEPGPVPAVAT-LPG-----AASAGVS
MAB_1974|M.abscessus_ATCC_1997 LQVQIAVVKSQYNTLSPGQRAQLAAPAPVPPPP-------AAEPGEAGDA
** ** :**::* :*:. :* *. . ..
Mflv_2959|M.gilvum_PYR-GCK DPAILAAPPAPPVP--GAIPPGDIAPPG--SPAATTVIQAALSRIGSPYS
Mvan_3552|M.vanbaalenii_PYR-1 DPAVLAAPPAPPAL--GAIPPGDIAPPG--SPVSSTVIQAALSRIGSPYS
MSMEG_4256|M.smegmatis_MC2_155 DPGVLAAPPEGIPP--GDIAPPDAAIPGGPSPVSNTVIQAALSRIGSPYS
TH_3014|M.thermoresistible__bu DTEVLAAP--GIPP--GDLAP-EAAVPGGPSNDRATVVQAALSRIGSPYS
MUL_3545|M.ulcerans_Agy99 PPAGAPVPGEAPPPGAGGVSAMPFTPPDGAGGDRAAVVQAALTQVGTPYA
MMAR_3234|M.marinum_M PPAGAPVPGEAPPP--GGVSAMPFTPPDGAGGDRAAVVQAALTQVGTPYA
Mb2213c|M.bovis_AF2122/97 PPGDGPAPGVAPPP--GGMPGLPFVQPDGAGGDRTAVVQAALTQVGAPYA
Rv2190c|M.tuberculosis_H37Rv PPGDGPAPGVAPPP--GGMPGLPFVQPDGAGGDRTAVVQAALTQVGAPYA
MAV_2304|M.avium_104 TPPGGPGPGEAPPP--GGAPGMAPGGGGVGGGDRATVVQAALTQVGSPYV
MLBr_00885|M.leprae_Br4923 PPPD------AAPP--GGLLGVAP-APFAGGGDRAAVVQAALTQIGSPYA
MAB_1974|M.abscessus_ATCC_1997 PEPLMQAAAAAPAP--------EAAIGGGGSPAGAGAVAAALTRIGAPYS
. .: ***:::*:**
Mflv_2959|M.gilvum_PYR-GCK WGGSGPGAFDCSGLVMWSFQQ-AGIALPHSSQALARGGQPVSTDQMQPGD
Mvan_3552|M.vanbaalenii_PYR-1 WGGSGPGAFDCSGLVMWSFQQ-AGISLPHSSQALARGGQPVSMDQMQPGD
MSMEG_4256|M.smegmatis_MC2_155 WGGSGPNAFDCSGLVMWSFQQ-AGISLPHSSQALARGGQPVSMDNIQPGD
TH_3014|M.thermoresistible__bu WGGSGPNAFDCSGLVMWAFRQGAGINLPHSSQALARGGQPVSMADIQPGD
MUL_3545|M.ulcerans_Agy99 WGGAAPGGFDCSGLVMWAFQQ-AGIALPHSSQALAHEGQPVSLSDLQPGD
MMAR_3234|M.marinum_M WGGAAPGGFDCSGLVMWAFQQ-AGIALPHSSQALAHGGQPVSLSDLQPGD
Mb2213c|M.bovis_AF2122/97 WGGAAPGGFDCSGLVMWAFQQ-AGIALPHSSQALAHGGQPVALSDLQPGD
Rv2190c|M.tuberculosis_H37Rv WGGAAPGGFDCSGLVMWAFQQ-AGIALPHSSQALAHGGQPVALSDLQPGD
MAV_2304|M.avium_104 WGGAAPGGFDCSGLVMWAFQQ-AGISLPHSSQALAHGGQPVSLSDLQPGD
MLBr_00885|M.leprae_Br4923 WGGAAPGGFDCSGLVMWAYQQ-AGIALPHSSQALARGGQPVSLSELQPGD
MAB_1974|M.abscessus_ATCC_1997 WGGSGPNAFDCSGLVMWAYGQ-QGVSLPHSSQALARGGTPVSLSELQPGD
***:.*..*********:: * *: *********: * **: ::****
Mflv_2959|M.gilvum_PYR-GCK LVTYYSDASHVGIYIGDGMMVHASTYGTPVRVAPVNN-APIYNVRRY
Mvan_3552|M.vanbaalenii_PYR-1 LVTYYSDASHVGIYIGDGMMVHASTYGTPVRVAPVNN-APIHNVRRY
MSMEG_4256|M.smegmatis_MC2_155 LVTYYSDASHVGIYIGDGMMVHASTYGSPVRVAPVNN-APIYNVRRY
TH_3014|M.thermoresistible__bu VVTYYSDASHAAIYIGNGMMVHASTYGTPVRVAPVNN-APIYNIRRY
MUL_3545|M.ulcerans_Agy99 VLTFYSDASHAGIYIGDGLMVHSSTYGVPVRVVPMNSSGPIYDARRY
MMAR_3234|M.marinum_M VLTFYSDASHAGIYIGDGLMVHSSTYGVPVRVVPMNSSGPIYDARRY
Mb2213c|M.bovis_AF2122/97 VLTFYSDASHAGIYIGDGLMVHSSTYGVPVRVVPMDSSGPIYDARRY
Rv2190c|M.tuberculosis_H37Rv VLTFYSDASHAGIYIGDGLMVHSSTYGVPVRVVPMDSSGPIYDARRY
MAV_2304|M.avium_104 VLTFYSDASHAGIYIGDGMMIHSSTYGVPVRVVPMNSSGPIYDARRY
MLBr_00885|M.leprae_Br4923 VLTFYSDASHAGIYVGDGMMIHSSTYGVPVRVVPMNSSGPIYDARRY
MAB_1974|M.abscessus_ATCC_1997 VINFYGDASHTGIYVGNGMMVHASTYGVPVAVVPITSSGPIYNARRY
::.:*.****..**:*:*:*:*:**** ** *.*: . .**:: ***