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IHSPSTQAQTQYVQGRLARFAYRRFGSGAGVPLVLALRFRGTMDHWDPAFLDRLAATHDVVVFDNVGHSK STGTPPTTMAELAGGLIDFVGALGLDEIDLLGWSLGGIVVQEVALQRPELVRRLVVAGSSPGGGVPGMPE PDPRIWQVATKPVNDDEDFLYLFFPETEPGRKLGVESLRRLDRRTTAPDHVPVSAETMTAQLKVIASTGS RIWDRLNDITVPVLVANGAHDRMIDAYASYAMAGRLPDAKIVLYSDAGHGFLFQHLPDFAREVTEFLAGN RP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6831 | - | - | 100% (283) | hydrolase, alpha/beta hydrolase fold family protein |
| M. smegmatis MC2 155 | MSMEG_3856 | - | 5e-08 | 24.29% (247) | transcriptional regulator, CadC |
| M. smegmatis MC2 155 | MSMEG_2900 | - | 5e-08 | 23.32% (223) | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3203 | - | 6e-47 | 38.97% (272) | peroxidase |
| M. gilvum PYR-GCK | Mflv_3952 | - | 4e-10 | 26.60% (282) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv3177 | - | 6e-47 | 38.97% (272) | peroxidase |
| M. leprae Br4923 | MLBr_02269 | - | 8e-10 | 24.33% (263) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_3880 | - | 1e-13 | 24.07% (295) | lipase/esterase LipG |
| M. marinum M | MMAR_1997 | - | 4e-10 | 23.36% (304) | hydrolase |
| M. avium 104 | MAV_3609 | - | 3e-09 | 23.16% (285) | hydrolase |
| M. thermoresistible (build 8) | TH_3727 | - | 1e-11 | 28.46% (267) | PUTATIVE Chloride peroxidase |
| M. ulcerans Agy99 | MUL_3358 | - | 3e-10 | 23.36% (304) | hydrolase |
| M. vanbaalenii PYR-1 | Mvan_0113 | - | 3e-13 | 24.09% (274) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3203|M.bovis_AF2122/97 MPQRQAGDIGATYQDAPTKSINVGGTRFVYRRLGADA-GVPVIFLHHLGA
Rv3177|M.tuberculosis_H37Rv MPQRQAGDIGATYQDAPTKSINVGGTRFVYRRLGADA-GVPVIFLHHLGA
MSMEG_6831|M.smegmatis_MC2_155 -------MIHSPSTQAQTQYVQGRLARFAYRRFGSGA-GVPLVLALRFRG
MAB_3880|M.abscessus_ATCC_1997 -----MSTTAREISEMTASTATVGDIELCYEEFGNPA-DPAVLLIMGIGA
Mvan_0113|M.vanbaalenii_PYR-1 -----------MTSEQIAHGVGPDRLDIAYRRHGHSG-DPAAVLIMGIAA
MMAR_1997|M.marinum_M MTERKRN--LRPVREVTAPSLQFRTIHGYKRAFRIAGSGPAILLIHGIGD
MUL_3358|M.ulcerans_Agy99 MTERKRN--LRPVREVTAPSLQFRTIHGYKRAFRIAGSGPAILLIHGIGD
MAV_3609|M.avium_104 MTERKRKNTLRPVREVSAPRLEFRTIHGYRRAYRIAGSGPAILLIHGIGD
Mflv_3952|M.gilvum_PYR-GCK MTARTPN--LRPVRELT-PTLRYCTIHGYRRAYRIAGSGPAILLIHGIGD
MLBr_02269|M.leprae_Br4923 ---------------------------MINLAYEDRGTGEPVVFIAGRGG
TH_3727|M.thermoresistible__bu ----------------MATITTSDGVEIFYRDWGSGQ---PIVFSHGWPL
. ::
Mb3203|M.bovis_AF2122/97 VLDNWDPRVVDGIAAK-HPVVTFDNRGVGASE------------------
Rv3177|M.tuberculosis_H37Rv VLDNWDPRVVDGIAAK-HPVVTFDNRGVGASE------------------
MSMEG_6831|M.smegmatis_MC2_155 TMDHWDPAFLDRLAAT-HDVVVFDNVGHSKST------------------
MAB_3880|M.abscessus_ATCC_1997 QMVFWRPEFCQQLADQGYRVIRFDNRDCGLSTKLDGVRAGGGSLIPSMAK
Mvan_0113|M.vanbaalenii_PYR-1 QLVNWPPEFIRALTDRGLQVIVFDNRDTGRSTHLDSAPAD-------LSA
MMAR_1997|M.marinum_M NSTTWT-GIHAKLAQR-FTVIAPDLLGHGRSDK-----------------
MUL_3358|M.ulcerans_Agy99 NSTTWT-GIHAKLAQR-FTVIAPDLLGHGRSDK-----------------
MAV_3609|M.avium_104 NSTTWN-TVQAKLAQR-FTVIAPDLLGHGQSDK-----------------
Mflv_3952|M.gilvum_PYR-GCK NSTTWA-GVQTQLAQR-FTVIAPDLLGHGKSDK-----------------
MLBr_02269|M.leprae_Br4923 AGRTWQPHQVPAFLAAGYRVITFDNRGIGATEN-----------------
TH_3727|M.thermoresistible__bu TADDWDPQMLFFLNAG-YRVIAHDRRGHGRSSP-----------------
* : *: * . . :
Mb3203|M.bovis_AF2122/97 -------GQTPDTVTTMADDAIAFVRALGFDQVDLLGFSLGGFVAQVIAQ
Rv3177|M.tuberculosis_H37Rv -------GQTPDTVTTMADDAIAFVRALGFDQVDLLGFSLGGFVAQVIAQ
MSMEG_6831|M.smegmatis_MC2_155 -------GTPPTTMAELAGGLIDFVGALGLDEIDLLGWSLGGIVVQEVAL
MAB_3880|M.abscessus_ATCC_1997 FLAGVKITGTAYTLVDMAGDAAGLLDHLGIEQAHIVGASMGGMIAQVFAA
Mvan_0113|M.vanbaalenii_PYR-1 VQAG-DLTSVSYTLSDMAADTVGLMDHLGIRAAHLVGASMGGAIAQTIAI
MMAR_1997|M.marinum_M -------PRADYSIAAYANGMRDLLSVLDIERVTIIGHSLGGGVAMQFAY
MUL_3358|M.ulcerans_Agy99 -------PRADYSIAAYANGMRDLLSVLDIERVTIIGHSLGGGVAMQFAY
MAV_3609|M.avium_104 -------PRADYSVAAYANGMRDLLAVLDIERVTIVGHSLGGGVAMQFAY
Mflv_3952|M.gilvum_PYR-GCK -------PRADYSVAAYANGMRDLLSVLNIDSATVVGHSLGGGVAMQFAY
MLBr_02269|M.leprae_Br4923 --------TEGFTTQTMVADTAVLIESLGAVPARIVGVSMGSFIAQELMV
TH_3727|M.thermoresistible__bu -------VPDGHDMDHYADDLAALVEHLGLRDAVHVGHSTGGGVVVRYLA
. . :: *. :* * *. :.
Mb3203|M.bovis_AF2122/97 QEPQ--LVRKIILAGTGPAGGVGIGKVTFGTIRESIKATLTFRDPKELRF
Rv3177|M.tuberculosis_H37Rv QEPQ--LVRKIILAGTGPAGGVGIGKVTFGTIRESIKATLTFRDPKELRF
MSMEG_6831|M.smegmatis_MC2_155 QRPE--LVRRLVVAGSSPGGGVPGMPEPDPRIWQVATKPVNDDEDFLYLF
MAB_3880|M.abscessus_ATCC_1997 EHPDRTATVSIIMSSNNQPFLPPPGPRQLMALLKPPPEGASREQIIANSV
Mvan_0113|M.vanbaalenii_PYR-1 EHPDRTLSLSSMMSTTGAPEVGAAHPDVMAALFGEPP-VTTREEEAARAI
MMAR_1997|M.marinum_M QFPQLVDRLILVGAGGVTKDVNVVFRLASLPMGAEALALLRLPMVLPTVQ
MUL_3358|M.ulcerans_Agy99 QFPQLVDRLILVGAGGVTKDVNVVFRLASLPMGAEALALLRLPMVLPTVQ
MAV_3609|M.avium_104 QFPHLVERLILVGAGGVTKDVNFVLRWASLPLGSEAIALLRLPLVLPAVQ
Mflv_3952|M.gilvum_PYR-GCK QFPQLVDRLILVGAGGVTKDVNIALRAASLPMGTEALALLRLPLLLPTLR
MLBr_02269|M.leprae_Br4923 ARPELVRAAVLMATRGRLDRTRQFFHAAEAEFHDSGIQLPSGYNAKVRLL
TH_3727|M.thermoresistible__bu RHGEERTAKAVLIAAVPPLMVR--TDANPGGLPKSVFDDFQAQLAANRSE
. : : :
Mb3203|M.bovis_AF2122/97 FTRTDSGKSAARQFVKRLKE---RKDNRDKS-ITVRAFRSQLKAIHAWG-
Rv3177|M.tuberculosis_H37Rv FTRTDSGKSAARQFVKRLKE---RKDNRDKS-ITVRAFRSQLKAIHAWG-
MSMEG_6831|M.smegmatis_MC2_155 FPETEPGRKLGVESLRRLDR---RTTAPDHVPVSAETMTAQLKVIASTG-
MAB_3880|M.abscessus_ATCC_1997 QVGRIIGSPKYRQSQSKSYL---HAAEYYDRSYYPKGFSRQFAAIMGTG-
Mvan_0113|M.vanbaalenii_PYR-1 RAATVVGSPAYPPDPAAIAR---RAGIAYDRSHDIAGITRNAVAVVASG-
MMAR_1997|M.marinum_M LAGKVLGMALGSTALGQDLPNVLRILDDLPEPTASSAFTRTLRAVVDWRG
MUL_3358|M.ulcerans_Agy99 LAGKVLGMALGSTALGQDLPNVLRILDDLPEPTASSAFTRTLRAVVDWRG
MAV_3609|M.avium_104 LMGRVLGTALGSTGLGRDLPNVLRILDDLPEPTASAAFSRTLRAVVDWRG
Mflv_3952|M.gilvum_PYR-GCK LLGRVGGPLLGNTRIGRDIPNMLRILADLPEPTASSAFARTLRSVVDWRG
MLBr_02269|M.leprae_Br4923 ENLSRKTLNDDVAVADWIAMFNMWPIKSTPGLRCQTDVAPQNNRLPAYR-
TH_3727|M.thermoresistible__bu FYRALASGPFYGFNRDGVEPSE-ALIANWWRQGMMGDAKAHYDGIVAFS-
:
Mb3203|M.bovis_AF2122/97 ---TQKPSDLTSIGHPVLIANGDDDTMVPTSN-SLDLADRLPDATLRIYP
Rv3177|M.tuberculosis_H37Rv ---TQKPSDLTSIGHPVLIANGDDDTMVPTSN-SLDLADRLPDATLRIYP
MSMEG_6831|M.smegmatis_MC2_155 ---SRIWDRLNDITVPVLVANGAHDRMIDAYA-SYAMAGRLPDAKIVLYS
MAB_3880|M.abscessus_ATCC_1997 ---SLAP-FDNRITAPALVLHGKADKLMRPSG-ARAIARAIPGSRLALID
Mvan_0113|M.vanbaalenii_PYR-1 ---DRTG-ALRTLKIPTLVIHGRADRMCDPSG-GRATAAAIPGAQLELID
MMAR_1997|M.marinum_M QIVTMLDRCYLTQAIPVQIIWGSRDAVVPVRH-AEMAHAAMPGSKLEVFE
MUL_3358|M.ulcerans_Agy99 QIVTMLDRCYLTQAIPVQIIWGSRDAVVPVRH-AEMAHAAMPGSKLEVFE
MAV_3609|M.avium_104 QIVTMLDRCYLTEAIPVQIVWGTKDVVVPVRH-AWMAHAAMPGSRLEIFE
Mflv_3952|M.gilvum_PYR-GCK QVVTMLDRCYLTQSVPVQLIWGSQDSVIPVSH-AEMAHTAMPGSRLEIFE
MLBr_02269|M.leprae_Br4923 -----------SIAAPVLVIGFAEDVVTPPSL-GREVADVLPNGRYLQIP
TH_3727|M.thermoresistible__bu --QTDFTEDLTKITVPVLVMHGDDDQVVPYANSGPLTAELLRNAKLKTYQ
*. : * : . : ..
Mb3203|M.bovis_AF2122/97 DAGHGGIFQHHAQFVDDALQFLES--------------------------
Rv3177|M.tuberculosis_H37Rv DAGHGGIFQHHAQFVDDALQFLES--------------------------
MSMEG_6831|M.smegmatis_MC2_155 DAGHGFLFQHLPDFAREVTEFLAGNRP-----------------------
MAB_3880|M.abscessus_ATCC_1997 GMGHDLPEPLWNHIITKLTENFARSEPAAETPESEAAGR-----------
Mvan_0113|M.vanbaalenii_PYR-1 GMGHDIPAPLYDRIADLIAENARRSDHLQFKTRAPSTHTP----------
MMAR_1997|M.marinum_M GSGHFPFHDDPARFIDIVLRFIDSTQPPEYDQAALRELLRTGGGERTVSG
MUL_3358|M.ulcerans_Agy99 GSGHFPFHDDPARFIDIVLRFIDSTQPPEYDQAALRELLRTGGGERTVSD
MAV_3609|M.avium_104 GSGHFPFHDDPARFIDVVERFIDSTEPAAYDQEALRRLLRSGGGAQAVTG
Mflv_3952|M.gilvum_PYR-GCK GAGHFPFHDEPDRFVELVEKFIDSTEPAVYDQEYLRTLLRTGTSENTLSG
MLBr_02269|M.leprae_Br4923 DAGHLGFFERPEAVNAAALQFFAGVKGEWP--------------------
TH_3727|M.thermoresistible__bu GFPHGMMTTHAEVVNADILEFLRS--------------------------
. * . .
Mb3203|M.bovis_AF2122/97 --------------------
Rv3177|M.tuberculosis_H37Rv --------------------
MSMEG_6831|M.smegmatis_MC2_155 --------------------
MAB_3880|M.abscessus_ATCC_1997 --------------------
Mvan_0113|M.vanbaalenii_PYR-1 --------------------
MMAR_1997|M.marinum_M PADTRVAVLSAMGSDERSAT
MUL_3358|M.ulcerans_Agy99 PADTRVAVLSAMGSDERSAT
MAV_3609|M.avium_104 PAPTRVAVLSAMGSDERSAT
Mflv_3952|M.gilvum_PYR-GCK DVDTQVAVLDAIGADERSAT
MLBr_02269|M.leprae_Br4923 --------------------
TH_3727|M.thermoresistible__bu --------------------