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TSEQIAHGVGPDRLDIAYRRHGHSGDPAAVLIMGIAAQLVNWPPEFIRALTDRGLQVIVFDNRDTGRSTH LDSAPADLSAVQAGDLTSVSYTLSDMAADTVGLMDHLGIRAAHLVGASMGGAIAQTIAIEHPDRTLSLSS MMSTTGAPEVGAAHPDVMAALFGEPPVTTREEEAARAIRAATVVGSPAYPPDPAAIARRAGIAYDRSHDI AGITRNAVAVVASGDRTGALRTLKIPTLVIHGRADRMCDPSGGRATAAAIPGAQLELIDGMGHDIPAPLY DRIADLIAENARRSDHLQFKTRAPSTHTP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0113 | - | - | 100% (310) | alpha/beta hydrolase fold |
| M. vanbaalenii PYR-1 | Mvan_1240 | - | 1e-54 | 43.12% (276) | alpha/beta hydrolase fold |
| M. vanbaalenii PYR-1 | Mvan_2912 | - | 6e-15 | 27.06% (303) | alpha/beta hydrolase fold |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0665c | lipG | 2e-51 | 40.71% (280) | lipase/esterase LipG |
| M. gilvum PYR-GCK | Mflv_5112 | - | 8e-56 | 43.12% (276) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv0646c | lipG | 2e-51 | 40.71% (280) | lipase/esterase LipG |
| M. leprae Br4923 | MLBr_01899 | lipG | 2e-52 | 39.72% (287) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_3880 | - | 4e-64 | 42.27% (317) | lipase/esterase LipG |
| M. marinum M | MMAR_0981 | lipG1 | 3e-52 | 41.55% (284) | lipase/esterase LipG1 |
| M. avium 104 | MAV_4515 | - | 6e-50 | 38.59% (298) | hydrolase, alpha/beta fold family protein |
| M. smegmatis MC2 155 | MSMEG_1352 | - | 6e-55 | 41.61% (286) | hydrolase, alpha/beta fold family protein |
| M. thermoresistible (build 8) | TH_1861 | lipG | 1e-58 | 43.21% (287) | PROBABLE LIPASE/ESTERASE LIPG |
| M. ulcerans Agy99 | MUL_0733 | lipG1 | 7e-52 | 40.48% (289) | lipase/esterase LipG1 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1352|M.smegmatis_MC2_155 -MQTRTGLARAGDAD---------HPIDLFYEDMGDPGDPAVLLIMGLGA
TH_1861|M.thermoresistible__bu -MQIRTGFANVDGSP---------EPVDLYYEDLGDPADPPVLLIMGLGA
Mflv_5112|M.gilvum_PYR-GCK -MQVRTGTARSGE-------------LEIHYEDMGDPNDPAVLLIMGLGA
Mb0665c|M.bovis_AF2122/97 -MDIRSGTAVS-------------GDVKLYYEDMGDLDHPPVLLIMGLGA
Rv0646c|M.tuberculosis_H37Rv -MDIRSGTAVS-------------GDVKLYYEDMGDLDHPPVLLIMGLGA
MAV_4515|M.avium_104 MVQVRTGHAIS-------------GDLKLYYEDMGDIDDPPVLLIMGLGA
MMAR_0981|M.marinum_M -MEIRTGYAQSGVGSGATSERQPAGDLKLYYEDMGDINAPPVLLIMGLGA
MUL_0733|M.ulcerans_Agy99 -MEIRTGYAQSGVGSGATSERQPAGDLKLYYEDMGDINAPPVLLIMGLGA
MLBr_01899|M.leprae_Br4923 -MEVRSGYATS-------------GDLKLYYEDMGNVDDPPVLLIMGLGA
MAB_3880|M.abscessus_ATCC_1997 -MSTTAREISEMTAS-----TATVGDIELCYEEFGNPADPAVLLIMGIGA
Mvan_0113|M.vanbaalenii_PYR-1 -MTSEQIAHGVGP-----------DRLDIAYRRHGHSGDPAAVLIMGIAA
: :.: *. *. *..:****:.*
MSMEG_1352|M.smegmatis_MC2_155 QMLMWRTEFCEKLVDQGLRVIRFDNRDVGLSTKLS---GQRVDSPLALRM
TH_1861|M.thermoresistible__bu QLILWRDGFCRKLVERGLRVIRFDNRDVGLSSKLD---GRRERTPLPWRM
Mflv_5112|M.gilvum_PYR-GCK QLLLWRKGFCEKLINQGLRVIRFDNRDVGLSSKLT---GHHAGAPLLPRM
Mb0665c|M.bovis_AF2122/97 QMLLWRTDFCARLVAKGLRVIRYDNRDVGLSTKTE---RHRPGQPLATRL
Rv0646c|M.tuberculosis_H37Rv QMLLWRTDFCARLVAKGLRVIRYDNRDVGLSTKTE---RHRPGQPLATRL
MAV_4515|M.avium_104 QLLLWRTAFCEKLVGRGLRVIRYDNRDVGLSSKTE---HRSSGQPLVTRL
MMAR_0981|M.marinum_M QLLLWRTGFCQKLVDQGLRVIRYDNRDVGLSTKME---QPSARQPLMPQL
MUL_0733|M.ulcerans_Agy99 QLLLWRTGFCQKPVDQGLRVIRYDNRDVGLSTKME---QPSARQPLMPQL
MLBr_01899|M.leprae_Br4923 QLVLWRTAFCEKLVAQGLRVVRYDNRDVGLSSRTDSTEQPCPSQPLTARL
MAB_3880|M.abscessus_ATCC_1997 QMVFWRPEFCQQLADQGYRVIRFDNRDCGLSTKLDG--VRAGGGSLIPSM
Mvan_0113|M.vanbaalenii_PYR-1 QLVNWPPEFIRALTDRGLQVIVFDNRDTGRSTHLD---------SAPADL
*:: * * :* :*: :**** * *:: . :
MSMEG_1352|M.smegmatis_MC2_155 ARSFLGKRSP-AVYTLEDMADDAAALLDHLEIDRAHIVGGSMGGMIAQVF
TH_1861|M.thermoresistible__bu LRSFAGLPSP-AVYTLEDMADDAAGLLDHLQIDAAHIVGASMGGMVAQVF
Mflv_5112|M.gilvum_PYR-GCK ARSLAGLPSP-AAYTLEDMADDAAALLDHLDIDRAHVVGGSMGGMIAQVF
Mb0665c|M.bovis_AF2122/97 VRSWLGLPSQ-AAYTLEDMAADAAALLDHLDVKHAHVVGASMGGMIAQIF
Rv0646c|M.tuberculosis_H37Rv VRSWLGLPSQ-AAYTLEDMAADAAALLDHLDVKHAHVVGASMGGMIAQIF
MAV_4515|M.avium_104 LRSWLGLPSQ-SAYRLEDMADDAAAVLDHLGIDDAHIVGASMGGMIAQIF
MMAR_0981|M.marinum_M IRSWLGRRSQ-TPYTLEDMADDAAALLDHLDIERAHIVGASMGGMIAQIF
MUL_0733|M.ulcerans_Agy99 IRSWLGRRSQ-TPYTLEDMADDAAALLDHLDIERAHIVGASMGGMIAQIF
MLBr_01899|M.leprae_Br4923 IRFWLGQRNA-CAYTLEDMTDDAVALLDHLSIERAHIVGASMGGMIAQIF
MAB_3880|M.abscessus_ATCC_1997 AKFLAGVKITGTAYTLVDMAGDAAGLLDHLGIEQAHIVGASMGGMIAQVF
Mvan_0113|M.vanbaalenii_PYR-1 SAVQAGDLTS-VSYTLSDMAADTVGLMDHLGIRAAHLVGASMGGAIAQTI
* * * **: *:..::*** : **:**.**** :** :
MSMEG_1352|M.smegmatis_MC2_155 ASQHAARTETLGVIFSSNNQALLPPPGIRQLLSLITGPPADASRDAVLDN
TH_1861|M.thermoresistible__bu AGRHAHRTRSLGVIFSSNNRPFLPPPGPRQLLSIITGPAPDAPRDEVIEN
Mflv_5112|M.gilvum_PYR-GCK AARHHPRTKTLGVIFSSNNQAALPPPGPRQLAAILQRPK-GSSRDEIVDN
Mb0665c|M.bovis_AF2122/97 AARFAQRTKTLAVIFSSNNHRFLPPPAPRALLALLTGPPPDSPRDVIVDN
Rv0646c|M.tuberculosis_H37Rv AARFAQRTKTLAVIFSSNNHRFLPPPAPRALLALLTGPPPDSPRDVIVDN
MAV_4515|M.avium_104 AARFRQRTKTLAVIFSSNNSALLPPPAPRALLALLKGPPPDSPREVIIDN
MMAR_0981|M.marinum_M AARFAERTNSLAVIFSSNNRPFLPPPAPRALLAVLNGPPPGSPREVIIDN
MUL_0733|M.ulcerans_Agy99 AARFAERTNSLAVIFSSNNRPFLPPPAPRALLAVLNGPPPGSPREVIIDN
MLBr_01899|M.leprae_Br4923 AARFPTRTRSLAVFFSSNNRPFLPPPAPRALLALLTGPPTGSRRDVVVDN
MAB_3880|M.abscessus_ATCC_1997 AAEHPDRTATVSIIMSSNNQPFLPPPGPRQLMALLKPPPEGASREQIIAN
Mvan_0113|M.vanbaalenii_PYR-1 AIEHPDRTLSLSSMMSTTGAPEVGAAHP-DVMAALFGEPPVTTREEEAAR
* .. ** ::. ::*:.. : .. : : : : *: .
MSMEG_1352|M.smegmatis_MC2_155 AVRLSRLNGSPAYPRSEEEIRAEAAELYDRAYYPAGIARHFAAILGSGSL
TH_1861|M.thermoresistible__bu AVKVGRLNGSPAYPVPDEQLRADAATAFDRSYHPVGVARQFDAILGSGSL
Mflv_5112|M.gilvum_PYR-GCK AVRVSRIIGSPGYPAPLDRLRTDAIEGFDRSYYPAGVGRHFAAILGSGSL
Mb0665c|M.bovis_AF2122/97 AVRVSKIIGSPAYPIPEDQVRAEAAESYDRNFHPWGIAQQFSAILGSGSL
Rv0646c|M.tuberculosis_H37Rv AVRVSKIIGSPAYPIPEDQVRAEAAESYDRNFHPWGIAQQFSAILGSGSL
MAV_4515|M.avium_104 AVRVGRIIGSTRYRVPEEQARAEAAEGYDRNYYPQGVARHFSAVLGSGSL
MMAR_0981|M.marinum_M VVRVTRITGSPGYQPTEEWIRADAAENYDRSYYPWGIPRQFSAVLGSGSL
MUL_0733|M.ulcerans_Agy99 VVRVTRITGSPGYQPTEEWIRADAAENYDRSYYPWGIPRQFSAVLGSGSL
MLBr_01899|M.leprae_Br4923 VVRVTKITGSPLYRMPEEQVRTNAAEIYDRSFYPLGVSRQFSAILGSGSL
MAB_3880|M.abscessus_ATCC_1997 SVQVGRIIGSPKYRQSQSKSYLHAAEYYDRSYYPKGFSRQFAAIMGTGSL
Mvan_0113|M.vanbaalenii_PYR-1 AIRAATVVGSPAYPPDPAAIARRAGIAYDRSHDIAGITRNAVAVVASGDR
:: : **. * * :** . *. :: *::.:*.
MSMEG_1352|M.smegmatis_MC2_155 RHHNERVTAPTVVIHGRADRLMPPSGGRAIANAIRGARMVLIDGMGHELP
TH_1861|M.thermoresistible__bu RRYNRRTTSPTVVIHGRADKLMRPTGGRAVARAIPGARLTLFDGMGHDLP
Mflv_5112|M.gilvum_PYR-GCK RRYDRQITAPTVVIHGRADKLMRPSGGRAIARAIPGARLVLFDGMGHDLP
Mb0665c|M.bovis_AF2122/97 LRYDRRIVAPTVVIHGRADKLMRPFGGRAVARAINGARLVLIDGMGHDLP
Rv0646c|M.tuberculosis_H37Rv LRYDRRIVAPTVVIHGRADKLMRPFGGRAVARAINGARLVLIDGMGHDLP
MAV_4515|M.avium_104 RRYNRRTTAPTVVIHGRADKLMRPFGGRAVAGAIDGARLVLFDGMGHDLP
MMAR_0981|M.marinum_M LGYNRRTVAPTVVIHGRADKLMRPFGGRAVAKAINGARMVEFDGMGHDLP
MUL_0733|M.ulcerans_Agy99 LGYNRRTVAPTVVIHGRADKLMRPFGGRAVAKAINGARMVEFDGMGHDLP
MLBr_01899|M.leprae_Br4923 LHYNQRIIAPTVVIHGRADKLVRPSSGRAVARAITGARLVLFDGMGHDLP
MAB_3880|M.abscessus_ATCC_1997 APFDNRITAPALVLHGKADKLMRPSGARAIARAIPGSRLALIDGMGHDLP
Mvan_0113|M.vanbaalenii_PYR-1 TGALRTLKIPTLVIHGRADRMCDPSGGRATAAAIPGAQLELIDGMGHDIP
. *::*:**:**:: * ..** * ** *::: :*****::*
MSMEG_1352|M.smegmatis_MC2_155 EPVWDEVIGELKTNFAVVG--------------
TH_1861|M.thermoresistible__bu EPLWDEIVAELDKNITAGR--------------
Mflv_5112|M.gilvum_PYR-GCK EPLWDDIVGELKTTFAEAP--------------
Mb0665c|M.bovis_AF2122/97 RQLWDRVIGELTRNFSEAG--------------
Rv0646c|M.tuberculosis_H37Rv RQLWDRVIGELTRNFSEAG--------------
MAV_4515|M.avium_104 QQLWDQVIGVLANNFAKAS--------------
MMAR_0981|M.marinum_M RQLWDQVIGVLTSNFEQAK--------------
MUL_0733|M.ulcerans_Agy99 RQLWDQVIGVLTSNFEQAE--------------
MLBr_01899|M.leprae_Br4923 QQLWDQAVGVLMSNFAKAS--------------
MAB_3880|M.abscessus_ATCC_1997 EPLWNHIITKLTENFARSEPAAETPESEAAGR-
Mvan_0113|M.vanbaalenii_PYR-1 APLYDRIADLIAENARRSDHLQFKTRAPSTHTP
::: : .