For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
NQARIDVHHHVVPPQYRELLAAQTTNAGGRATPDWSVDSALGLMDSIGVETAILSITTPGVEPAERAQRP AVARDLNEFCADVVRSAPDRFGFWATLTLPDVDSAIGEAAYALDELHADGVVLLANSERTYLGDRRFDPL MEELDRRGATIFVHPSHLPGGSIPGINAYFADFLLDTTRAAINMVLNGTLDRYPNLRVILSHAGGFVPFI AERIATCVPIEHPDVSVESILDGLRKFYFDTALSASESALPSLLAFARPDHILFGSDFPYATAEIATRFA KNLDAYLADHQDVDGVAVNRDNALKLLPRLAVGAAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6813 | - | - | 100% (317) | amidohydrolase 2 |
| M. smegmatis MC2 155 | MSMEG_4043 | - | 2e-63 | 42.36% (314) | amidohydrolase 2 |
| M. smegmatis MC2 155 | MSMEG_5364 | - | 9e-25 | 25.89% (309) | amidohydrolase 2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0299 | - | 5e-31 | 32.27% (282) | putative amidohydrolase (aminocarboxymuconate-semialdehyde |
| M. marinum M | MMAR_1500 | - | 4e-75 | 46.65% (313) | hypothetical protein MMAR_1500 |
| M. avium 104 | MAV_2515 | - | 1e-82 | 50.64% (312) | amidohydrolase 2 |
| M. thermoresistible (build 8) | TH_0554 | - | 9e-08 | 26.53% (196) | amidohydrolase family protein |
| M. ulcerans Agy99 | MUL_2437 | - | 6e-75 | 46.96% (313) | hypothetical protein MUL_2437 |
| M. vanbaalenii PYR-1 | Mvan_0901 | - | 7e-09 | 25.65% (269) | amidohydrolase 2 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1500|M.marinum_M --------------------------------------------------
MUL_2437|M.ulcerans_Agy99 MGTRLEPHRGRRIHLGADDLPGNQHLGPYSRGTAHHRQVGPVQDGGAFVA
MAV_2515|M.avium_104 --------------------------------------------------
MSMEG_6813|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0299|M.abscessus_ATCC_1997 --------------------------------------------------
TH_0554|M.thermoresistible__bu ---------------------MSPRSLPYPVFDIDNHMYETTDALIKFLP
Mvan_0901|M.vanbaalenii_PYR-1 --------------MGSSTLIIDTDTHITEPPDLWTSRMSKSRWGNLIPE
MMAR_1500|M.marinum_M -----------------MWRIDTHHHMIPPDYRRALR-------------
MUL_2437|M.ulcerans_Agy99 AARGQRGAALRPGKEFAIWRIDTHHHMIPPDYRRALR-------------
MAV_2515|M.avium_104 -----------------MLRIDTHHHLIPPDYRKALQ-------------
MSMEG_6813|M.smegmatis_MC2_155 ---------------MNQARIDVHHHVVPPQYRELLA-------------
MAB_0299|M.abscessus_ATCC_1997 ---------------MTSVRIDIHAHLWSDEYLSLLDGYG----------
TH_0554|M.thermoresistible__bu REHRGKVGYVELNGRKKLMVKDRISHMIPNPTFEKVARPGSAEDYFLGNN
Mvan_0901|M.vanbaalenii_PYR-1 VKWVEEKQGEYWCMDGQPVFTVGTCIMVPGEDGKPVRSPR----------
: . :
MMAR_1500|M.marinum_M ------NAGVDGAGGRALPDWSPAGSLQAMAELTVGAAILSVSAPAT---
MUL_2437|M.ulcerans_Agy99 ------NAGVDGAGGRALPDWSPAGSLQAMAELTVGAAILSVSAPAT---
MAV_2515|M.avium_104 ------QKGIDEAGGRALPDWSPEASLQTMAELDVGTAILSVSTPGT---
MSMEG_6813|M.smegmatis_MC2_155 ------AQTTN-AGGRATPDWSVDSALGLMDSIGVETAILSITTPG----
MAB_0299|M.abscessus_ATCC_1997 ----RPATDVHRGLGAGATRDDLDGRFELMDEAGVDLQILTA-TPAS---
TH_0554|M.thermoresistible__bu PEGLNFREFVGEPMEVIPAFQHPAPRLELMDELGIDRCVMYPTLASL---
Mvan_0901|M.vanbaalenii_PYR-1 -----FPDYADRFSSMHPSAYDAKARLEVMDAYGIQAAAIFPNLGFVGPN
. : * : :
MMAR_1500|M.marinum_M AFLPQASDAAALARDINDY----AADIVAGRPTQFGFFATVPMPHLDQSV
MUL_2437|M.ulcerans_Agy99 AFLPQASDAAALARDINDY----AADVVAGRPAQFGFFATVPMPHLDQSV
MAV_2515|M.avium_104 TFLSEPADAAALARDLNDY----TAELAAAQPDRFGFFATVPMPHVDAAV
MSMEG_6813|M.smegmatis_MC2_155 VEPAERAQRPAVARDLNEF----CADVVRSAPDRFGFWATLTLPDVDSAI
MAB_0299|M.abscessus_ATCC_1997 PHFEDQAAAVASARFINDE----YAKLSSEYPGRFGALASLPLPHVPAAL
TH_0554|M.thermoresistible__bu IEERTTDDVVLTHAVMHALNQWMHEHWSFDYEGRIFATPVITLPIVEEAI
Mvan_0901|M.vanbaalenii_PYR-1 IFAAAGPDALEFQTAALQAYNDFLLDWSSIAPDRLLSLALIPYWDVDAAV
. :: . :. : ::
MMAR_1500|M.marinum_M AETVRALDDLKADGVVLLANHAG-----VYLGEDGQDDLFTALNSRAAVV
MUL_2437|M.ulcerans_Agy99 AETVRALDDLKADGVVLLANHAG-----VYLGEDGQDDLFTALNSRAAVV
MAV_2515|M.avium_104 AETVRALDELSADGVVLLANNAG-----VYVGQDGQDALFDALNHRSAVV
MSMEG_6813|M.smegmatis_MC2_155 GEAAYALDELHADGVVLLANSER-----TYLGDRRFDPLMEELDRRGATI
MAB_0299|M.abscessus_ATCC_1997 EELARAIDELGMYGASITTSVLG-----RSIADPIFDPLYAELNRRRAVL
TH_0554|M.thermoresistible__bu RELHWCLERGMRTFLVRPAPVPSRFGGSRSMGLPEFDPFWQEVVNAGIPV
Mvan_0901|M.vanbaalenii_PYR-1 AEIERCAAAGHKGLVSTGKPHEHG---YKLLADRYWDPMWAAAQDANLSI
* . :. * : :
MMAR_1500|M.marinum_M FVHPAELPGPA-------VPGVAPWAGDFLLDTTR-------AAHLLVRN
MUL_2437|M.ulcerans_Agy99 FVHPAELPGPA-------VPGVAPWAGDFLLDTTR-------AAHLLVRN
MAV_2515|M.avium_104 FIHPAELPGPT-------VPGVAPFAADFLLDTTR-------SAYLLVRN
MSMEG_6813|M.smegmatis_MC2_155 FVHPSHLPGGS-------IPGINAYFADFLLDTTR-------AAINMVLN
MAB_0299|M.abscessus_ATCC_1997 FVHPAGCGAESS----LITDHSLTWSIGAPIEDTV-------AIMHLIVA
TH_0554|M.thermoresistible__bu TMHASDSGYQKHLMEWEGGDEYLSFKPSALREVVMGHRAIEDTLAAMICH
Mvan_0901|M.vanbaalenii_PYR-1 SFHVGGGNLSRHLN--DERTSVEGWRATLARLTTSFFLESGITLADLLMS
.* . : . : ::
MMAR_1500|M.marinum_M GIRQRYPDIKFVLSHAG-GFVPYASHRLALAITADT---GRSPADVLEEF
MUL_2437|M.ulcerans_Agy99 GIRQRYPDINFVLSHAG-GFVPYASHRLALVITADT---GRSPADVLEEF
MAV_2515|M.avium_104 GIRNRYPNIRFLLSHAG-GFVPYASHRMAMAIMADT---GRSFADVLDDF
MSMEG_6813|M.smegmatis_MC2_155 GTLDRYPNLRVILSHAG-GFVPFIAERIATCVPIEHP--DVSVESILDGL
MAB_0299|M.abscessus_ATCC_1997 GVPSRYPDMKIVTCHLG-GALPMVLERAHRQVTEWEA--TQCPEAPRDAA
TH_0554|M.thermoresistible__bu GALSRFPDLKILCVENGSGWVRNLLEQLDTAYRIMPK--EFDEHPVEVFK
Mvan_0901|M.vanbaalenii_PYR-1 GVLARYPKLRFVSVESAVGWIPFLLESLDFHYKKYEPWLERPEFAGNDML
* *:*.:..: . . * : .
MMAR_1500|M.marinum_M SSFYFDTALSSS---AAALPTLIAFAKPGHITFGSDWPFAPTAAGKLFAA
MUL_2437|M.ulcerans_Agy99 SSFYFDTALSSS---AAALPTLIAFAKPGHITFGSDWPFAPTAAGKLFAA
MAV_2515|M.avium_104 SSFYFDTALSSS---AAALPSLLAFARPGHITFGSDWPFAPVAVGKLFAA
MSMEG_6813|M.smegmatis_MC2_155 RKFYFDTALSAS---ESALPSLLAFARPDHILFGSDFPYATAEIATRFAK
MAB_0299|M.abscessus_ATCC_1997 RRLWYDTVGHDH---TPALRAAVASLGVDRLIFGSDFPYQ---AGPRYVS
TH_0554|M.thermoresistible__bu RNIYIHPFLED------DVPGLIEIMGADHVLFGSDYPHP---EGIGDPL
Mvan_0901|M.vanbaalenii_PYR-1 PSDYFHRQVYANYWYEDLQPWHVAAIGEDNLMFETDYPHQTCLDKEEIQH
: . : ..: * :*:*.
MMAR_1500|M.marinum_M GLETYPALDAAARG-AIDRGSALSLFPRFGVAAPPPQPSAAQRIRHTLSR
MUL_2437|M.ulcerans_Agy99 GLETYPALDAAARG-AIDRGSALSLFPRFGVAAPPPQPSAAQRIRHTLSR
MAV_2515|M.avium_104 GLETYPALDTSTRG-AIEHTNALALFPRLGTPPHPIPQSPAQRIRHSLSR
MSMEG_6813|M.smegmatis_MC2_155 NLDAYLADHQDVDGVAVNRDNALKLLPRLAVGAAR---------------
MAB_0299|M.abscessus_ATCC_1997 SATYIEEGLSAEDASAILDHNGAELLGLTGV-------------------
TH_0554|M.thermoresistible__bu SFVDRLEGVSEADKAKIMGGNAMGLLGIRVPA------------------
Mvan_0901|M.vanbaalenii_PYR-1 SINEGLSGVSETTKEKILWRNAASLFNMDIAKLEKLT-------------
. : .. *:
MMAR_1500|M.marinum_M TAMRGVARLMNSGG
MUL_2437|M.ulcerans_Agy99 TAMRGVARLMNSGG
MAV_2515|M.avium_104 GAMRVVARMTSTS-
MSMEG_6813|M.smegmatis_MC2_155 --------------
MAB_0299|M.abscessus_ATCC_1997 --------------
TH_0554|M.thermoresistible__bu --------------
Mvan_0901|M.vanbaalenii_PYR-1 --------------