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PPTLELQSVIDRHPVGRLQRRVLMLCFGVLVLDGIDVAVVSFIAPSLIADWGISKAQLGPVVTSGLLGLA VGSLVAGPLADRFGRRKIIIGSLVFFGVMCTATALASGVVAFSILRVLTGFGLGAAMPNATTLVSEYAPA RRRSAMMAITYCGMTLGSAIAGYLTSVIVEIASWHWVLIVGGVLPVVYAVVVAVALPESPKYLARVPQRR AELSTLMSRIVPDHIPPDAQFTLDEPPAGNRAPFVALLVPRFRLGTLTIWVGFIAAFFIVYLMNSWLPIL MTDVGFALSTAATIGLLLQVGGTIGNIGIGWLMDRFGLHRIVAIGMGCAGVLLALIAVAPQEVVVIGVLI FVLGMFTNSVATGFPILSAAFYPTAIRATGTSWATGVARFGAIAGAAAGTVLVAFGMHYQQVFLTLLIPV AVCIAAVVTKGRKARTAGRAQTASPRSTEAQLPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6711 | - | - | 100% (455) | 4-hydroxybenzoate transporter |
| M. smegmatis MC2 155 | MSMEG_6718 | - | e-104 | 44.37% (435) | transporter, major facilitator family protein |
| M. smegmatis MC2 155 | MSMEG_3369 | - | 6e-36 | 25.98% (435) | putative transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0805c | emrB | 4e-18 | 31.05% (190) | multidrug resistance integral membrane efflux protein EmrB |
| M. gilvum PYR-GCK | Mflv_3055 | - | 6e-21 | 26.52% (411) | sugar transporter |
| M. tuberculosis H37Rv | Rv0783c | emrB | 4e-18 | 31.05% (190) | multidrug resistance integral membrane efflux protein EmrB |
| M. leprae Br4923 | MLBr_01562 | - | 3e-11 | 24.74% (477) | putative transmembrane efflux protein |
| M. abscessus ATCC 19977 | MAB_0692c | - | 2e-24 | 25.88% (452) | sugar transporter |
| M. marinum M | MMAR_2574 | - | 3e-22 | 25.45% (444) | sugar transporter |
| M. avium 104 | MAV_3053 | - | 1e-19 | 24.78% (452) | sugar transport protein |
| M. thermoresistible (build 8) | TH_2446 | - | 1e-14 | 25.19% (389) | PUTATIVE major facilitator superfamily MFS_1 |
| M. ulcerans Agy99 | MUL_1444 | sugI | 3e-22 | 25.47% (428) | sugar-transport integral membrane protein SugI |
| M. vanbaalenii PYR-1 | Mvan_3472 | - | 1e-22 | 27.56% (410) | sugar transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2574|M.marinum_M ----------------MSARAQTGTISTHVPARLDRLPWGR---------
MAV_3053|M.avium_104 ----------------MSAGAQTNTITTHVPARLDRLPWSR---------
Mflv_3055|M.gilvum_PYR-GCK ----------------MAGQGGPAGESPELYEKGQDFSSGK---------
Mvan_3472|M.vanbaalenii_PYR-1 ----------------MAGQGGPVGDGPEIFEQGQEFSSGK---------
MAB_0692c|M.abscessus_ATCC_199 ------------------------------MSEEDEFSSGH---------
Mb0805c|M.bovis_AF2122/97 -----------MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDV
Rv0783c|M.tuberculosis_H37Rv -----------MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDV
MUL_1444|M.ulcerans_Agy99 ------------------------------------MQRG----------
MSMEG_6711|M.smegmatis_MC2_155 -----------------------MPPTLELQSVIDRHPVGR---------
TH_2446|M.thermoresistible__bu ----------------VQPYAHPPGSALLNAVTLLDAPVAPHHDDDSAVT
MLBr_01562|M.leprae_Br4923 MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
MMAR_2574|M.marinum_M FHWRVVIGLGGVWVLDGLEVTMVGNVSARLTEHGSGINLTPAQIGVAASF
MAV_3053|M.avium_104 FHWRVVIGLGGVWVLDGLEVTMVGNVSARLMEPGSGIALNPAQIGMAAAI
Mflv_3055|M.gilvum_PYR-GCK TAIRIASVAALGGLLFGYDSAVINGAVASIQED---FGIGNYALGLAVAS
Mvan_3472|M.vanbaalenii_PYR-1 TAVRIASVAALGGLLFGYDSAVINGAVDSIQED---FGIGNAELGFAVAS
MAB_0692c|M.abscessus_ATCC_199 SALRIASVAALGGLLFGYDSAVINGAVQAIQDA---FAIRDAELGFAVAS
Mb0805c|M.bovis_AF2122/97 GLLRTAGVCVLASVMAHVDVTVVSVAQRTFVAD---FGSTQAVVAWTMTG
Rv0783c|M.tuberculosis_H37Rv GLLRTAGVCVLASVMAHVDVTVVSVAQRTFVAD---FGSTQAVVAWTMTG
MUL_1444|M.ulcerans_Agy99 --ILVALTAASVGLIYGYDLSIIAGAQLFITEE---FGLSTHQQELLTTM
MSMEG_6711|M.smegmatis_MC2_155 LQRRVLMLCFGVLVLDGIDVAVVSFIAPSLIAD---WGISKAQLGPVVTS
TH_2446|M.thermoresistible__bu PQARTALWASLVGTTIEWYDFFLYATAAGLVFNHAFFPDQSTFVGTMLSF
MLBr_01562|M.leprae_Br4923 PSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWGITA
: :
MMAR_2574|M.marinum_M YIAGA-----CLGALFFGHLTDRFGRRNLFLLTLAVY--------LTATV
MAV_3053|M.avium_104 YIAGA-----CSGALFFGHLTDRFGRRNLFILTLALY--------LIATV
Mflv_3055|M.gilvum_PYR-GCK ALLGA-----AVGALSAGRIADRIGRIAVMKIAAVLF--------LLSAF
Mvan_3472|M.vanbaalenii_PYR-1 ALLGA-----AAGAMTAGRIADRIGRIAVMKIAAVLF--------LVSAF
MAB_0692c|M.abscessus_ATCC_199 ALLGA-----AVGAMTAGRVADRIGRVAVMKIAAALF--------LLSAV
Mb0805c|M.bovis_AF2122/97 YMLAL-----ATVIPTAGWAADRFGTRRLFMGSVLAF--------TLGSL
Rv0783c|M.tuberculosis_H37Rv YMLAL-----ATVIPTAGWAADRFGTRRLFMGSVLAF--------TLGSL
MUL_1444|M.ulcerans_Agy99 VVIGQ-----IVGALGAGVLANAIGRKKSVVMLLVAY--------TMFAV
MSMEG_6711|M.smegmatis_MC2_155 GLLGL-----AVGSLVAGPLADRFGRRKIIIGSLVFF--------GVMCT
TH_2446|M.thermoresistible__bu ATFAVGFVVRPIGGVVFGHVGDRIGRKRTLALTMVLMGGATALMGVLPTA
MLBr_01562|M.leprae_Br4923 YVLTFG-----GLMLLGGRLGDTIGRKRTFIVGVALF--------TISSV
* : :* .
MMAR_2574|M.marinum_M ATAFAFAPWYFFIARFFTGSGIGGEYAAINSAIDELIP-ARVRGRVDLII
MAV_3053|M.avium_104 ATAFAFAPWYFFLTRFFTGAGIGGEYAAINSAIDELIP-ARVRGRVDLVI
Mflv_3055|M.gilvum_PYR-GCK GTAFAPETITLVIGRIVGGVGVGVASVIAPAYIAETSP-PGIRGRLGSLQ
Mvan_3472|M.vanbaalenii_PYR-1 GTGFAHEVWAVVLFRIVGGIGVGVASVIAPAYIAETSP-PGIRGRLGSLQ
MAB_0692c|M.abscessus_ATCC_199 GAGLAPNIELLVLFRVIGGVGVGVASLIAPAYIAETSP-SRIRGRLGSLQ
Mb0805c|M.bovis_AF2122/97 LCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAG-PKRLGRVMAVV
Rv0783c|M.tuberculosis_H37Rv LCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAG-PKRLGRVMAVV
MUL_1444|M.ulcerans_Agy99 LGALSVSLPMLLAARFLLGLAVGVSIVVVPVYVAESAP-AAVRGSLLTVY
MSMEG_6711|M.smegmatis_MC2_155 ATALASGVVAFSILRVLTGFGLGAAMPNATTLVSEYAP-ARRRSAMMAIT
TH_2446|M.thermoresistible__bu AQIGALAPILLLLLRIVQGFALGGEWAGAVLLAVEHGP-PRRRGLCGSIP
MLBr_01562|M.leprae_Br4923 LCAVAWDEVTLVIARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVF
: . *.. * . . . :
MMAR_2574|M.marinum_M NGTYWLGSAAGAAGALVLLDTSN------FAPNMGWRLAFGLG-AIFGIF
MAV_3053|M.avium_104 NGTYWLGSAAGAGGALILLDTSN------FAADLGWRLAFGIG-AILGIF
Mflv_3055|M.gilvum_PYR-GCK QLAIVSGIFASFAVNYLLQWLAGGPNEPLWLGMDAWRWMFLAM-AVPAVV
Mvan_3472|M.vanbaalenii_PYR-1 QLAIVSGIFASFAVNWLLQWAAGGPNEPLWFGLDAWRWMFLAM-ALPAVL
MAB_0692c|M.abscessus_ATCC_199 QLAIVTGIFLSLTIDWLLAHLAGSSRDELWLGLPAWRWMFLAM-ALPALV
Mb0805c|M.bovis_AF2122/97 GIPMLLGPVGGPILGGWLIGAYG----WRWIFLVNLPVGLSAL-VLAAIV
Rv0783c|M.tuberculosis_H37Rv GIPMLLGPVGGPILGGWLIGAYG----WRWIFLVNLPVGLSAL-VLAAIV
MUL_1444|M.ulcerans_Agy99 QLTTVSGLIVGYLTGYLLAGTHS------------WRWMLGLA-TVPAML
MSMEG_6711|M.smegmatis_MC2_155 YCGMTLGSAIAGYLTSVIVEIAS------------WHWVLIVGGVLPVVY
TH_2446|M.thermoresistible__bu QIGLALGLALGTGVFALLQIALP----DDAFLTYGWRIAFLLS-IVLVVF
MLBr_01562|M.leprae_Br4923 AAMTAIGSVMGLVVGGALTEVSWR-----------LAFLVNVPIGLVMIY
* . : . : :
MMAR_2574|M.marinum_M VLLVRRNVPESPRWLF-IHGREQEAEQIVREIEEEVERDTGQRLPDPPGR
MAV_3053|M.avium_104 VLLVRRNVPESPRWLF-IHGREEEAEHIVGEIEEAVQQQTGRPLPEPQGK
Mflv_3055|M.gilvum_PYR-GCK YGGLAFTIPESPRYLV-ATHKIPEARRVLSMLLGQKNLEITITRIRET--
Mvan_3472|M.vanbaalenii_PYR-1 YGVLAFTIPESPRYLV-ASHKIPEARRVLSMLLGKKNLEITITRIRET--
MAB_0692c|M.abscessus_ATCC_199 YGTLAFTIPESPRYLV-ATHRIPEARTVLATLLGEKNLDITIGRIQET--
Mb0805c|M.bovis_AF2122/97 FPRDRPAASENFDYMG-LLLLSPGLATFLFGVSSSPARGTMADRHVLIPA
Rv0783c|M.tuberculosis_H37Rv FPRDRPAASENFDYMG-LLLLSPGLATFLFGVSSSPARGTMADRHVLIPA
MUL_1444|M.ulcerans_Agy99 LLPLLIRMPDTPRWYV-MKGRIQEARAALLRVDPAADVEEELAE------
MSMEG_6711|M.smegmatis_MC2_155 AVVVAVALPESPKYLARVPQRRAELSTLMSRIVPDHIPPDAQFTLDEP--
TH_2446|M.thermoresistible__bu GVVVRLRATETPAFQR-VRDTGDRAAVPLRDVFR----------------
MLBr_01562|M.leprae_Br4923 LARTALHETHKERMKLDAAGAILATLACTAAVFAFSMGPEKGWISLTTIG
... :
MMAR_2574|M.marinum_M PLKIRQRQRISLWEIARVAF-TRYPRRAFLGLALFIGQAFLYNG------
MAV_3053|M.avium_104 ALRIRQRTAISFREIAAVAF-KLYPRRAVLGLALFIGQAFLYNG------
Mflv_3055|M.gilvum_PYR-GCK ---LEREDRPSWRDLKKPTG-GIYG-IVWVGLGLSIFQQFVGIN------
Mvan_3472|M.vanbaalenii_PYR-1 ---LEREDKPSWRDMRKPTG-GLYG-IVWVGLGLSIFQQFVGIN------
MAB_0692c|M.abscessus_ATCC_199 ---LDQSTAPSWRDLRKPTG-GLHA-IVWIGVALAVFQQLVGIN------
Mb0805c|M.bovis_AF2122/97 ITGLALIAAFVAHSWYRTEH-PLIDMRLFQNRAVAQANMTMTVLSLGLFG
Rv0783c|M.tuberculosis_H37Rv ITGLALIAAFVAHSWYRTEH-PLIDMRLFQNRAVAQANMTMTVLSLGLFG
MUL_1444|M.ulcerans_Agy99 ---IGTALSEGSGGVSEMLR-PPFLRATIFVITLGFLIQITGIN------
MSMEG_6711|M.smegmatis_MC2_155 ----PAGNRAPFVALLVPRF-RLGTLTIWVGFIAAFFIVYLMNS------
TH_2446|M.thermoresistible__bu ----PPVLRSTLLGLLSRWG-EGAAFNTWGVFAIAYATTTLGLA------
MLBr_01562|M.leprae_Br4923 SGLVALVAAIAFAVVERTAENPVVPFDLFRDRNRLVTFIAIFLAGGVIFS
MMAR_2574|M.marinum_M VTFNLGTLLSGFYGVESGHVPL-FFIVWALSNFVGPLVLGRLFDTVGRKP
MAV_3053|M.avium_104 VTFNLGTLLSQFYAVPSGMVPV-FFVLWALSNFAGPLLLGHLFDTVGRKQ
Mflv_3055|M.gilvum_PYR-GCK VIFYYSNVLWQAVGFSADESAV-YTVITSVVNVLTTLIAIALIDKIGRKP
Mvan_3472|M.vanbaalenii_PYR-1 VIFYYSNVLWQAVGFSADESAV-YTVITSVINVLTTLIAIALIDKIGRKP
MAB_0692c|M.abscessus_ATCC_199 VIFYYSNVLWQAVGFGESSSFT-ITVITSITNIATTLVAIALIDRVGRKP
Mb0805c|M.bovis_AF2122/97 SFLLLPSYLQQVLHQSPMQSGV-HIIPQGLGAMLAMPIAGAMMDRRGPAK
Rv0783c|M.tuberculosis_H37Rv SFLLLPSYLQQVLHQSPMQSGV-HIIPQGLGAMLAMPIAGAMMDRRGPAK
MUL_1444|M.ulcerans_Agy99 AIIYYSPRIFEAMGFTGDFALLGLPALVQIAGVAAVITSLLLVDRVGRRP
MSMEG_6711|M.smegmatis_MC2_155 ----WLPILMTDVGFALSTAAT-IGLLLQVGGTIGNIGIGWLMDRFGLHR
TH_2446|M.thermoresistible__bu ---------KVPVLVAVTAAALLMAVLLPVS--------GVLTDRFGAKR
MLBr_01562|M.leprae_Br4923 LTVSIGLYIQDILGYSALRAGI-GFIPFVIAMGIGLGVSSQLVSRFSPRV
: : . .
MMAR_2574|M.marinum_M MITMSYIGSAVIAVVLAVIFVN---------------QTGGVWTFIIVLA
MAV_3053|M.avium_104 MITLTYIGSAVVVVALALVFLT---------------QAGGVWAFIGVLI
Mflv_3055|M.gilvum_PYR-GCK LLLIGSVGMAVTLSTMAFIFANAELIENEAGE--MVPSLPGASGVIALIA
Mvan_3472|M.vanbaalenii_PYR-1 LLLIGSSGMAVTLITMAVIFANATVGADGN------PSLPGASGVIALIA
MAB_0692c|M.abscessus_ATCC_199 LLLIGSAGMAATLGTMAVIFGSATMVDGKP-------HLGPVAGPVALVA
Mb0805c|M.bovis_AF2122/97 IVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSG
Rv0783c|M.tuberculosis_H37Rv IVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSG
MUL_1444|M.ulcerans_Agy99 ILLSGIAIMIVADVALMAVFAR-----------------GQGAAILGFAG
MSMEG_6711|M.smegmatis_MC2_155 IVAIGMGCAGVLLALIAVAPQ----------------------EVVVIGV
TH_2446|M.thermoresistible__bu IYTIGITAYALAVFPVFALFGT-------------------GEIVFYTLG
MLBr_01562|M.leprae_Br4923 LTIGGGWLLMVAMLYGWAFMNRGVPYFPNLLAPIVVGGIGIGMAVVPLTL
: .
MMAR_2574|M.marinum_M AAFFLASAGAS---AAYLTVSEIFPMETRALAIAFFYAVGTAIGGISGPL
MAV_3053|M.avium_104 VAFFLASAGAS---AAYLTVSEIFPMETRALAIAFFYAMGTAIGGITGPL
Mflv_3055|M.gilvum_PYR-GCK ANLFVVAFGMSWGPVVWVLLGEMFPNRIRAAALGLAAAGQWTAN------
Mvan_3472|M.vanbaalenii_PYR-1 ANLFVVAFGMSWGPVVWVLLGEMFPNRIRAAALGLAAAGQWAAN------
MAB_0692c|M.abscessus_ATCC_199 ANLFVVAFGMSWGPVVWVLLGEIFPNRIRAAAMGLATAGNWAAN------
Mb0805c|M.bovis_AF2122/97 AAVQTLAPHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATA
Rv0783c|M.tuberculosis_H37Rv AAVQTLAPHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATA
MUL_1444|M.ulcerans_Agy99 ILLFIIGYTMGFGSLGWVYASESFPTRLRSIGSSTMLTANLIANAIVAAV
MSMEG_6711|M.smegmatis_MC2_155 LIFVLGMFTNSVATGFPILSAAFYPTAIRATGTSWATGVARFGAIAGAAA
TH_2446|M.thermoresistible__bu MLLVFGVIHALFYGAQGTLYASLFPARIRYTGLSTVYQLSGIFASGVTPM
MLBr_01562|M.leprae_Br4923 SAIAGVGFDRIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGP
.
MMAR_2574|M.marinum_M LFGQLIE---SGQRSQVFWSFIIGAAVMAVAGLVELWLGIAAEQRPLEEL
MAV_3053|M.avium_104 LFGQLID---SGQRDHVVWSFLIGAVVMAAAGLVELWLGIAAEQRPLEDL
Mflv_3055|M.gilvum_PYR-GCK WVITVSF---PELRNFLGAAYGFYALCAVLSGLFVWKWVRETKGVSLEDM
Mvan_3472|M.vanbaalenii_PYR-1 WLITVTF---PGLREHLGLAYGFYGLCAVLSGLFVWRWVMETKGVSLEDM
MAB_0692c|M.abscessus_ATCC_199 WAVTVTF---PALRDALGIAYGCYALCAVLSLLFVARWVEETKGRALEDM
Mb0805c|M.bovis_AF2122/97 KKVALTPESGAGRGAAVDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATAL
Rv0783c|M.tuberculosis_H37Rv KKVALTPESGAGRGAAVDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATAL
MUL_1444|M.ulcerans_Agy99 FLTMLHS-------LGGSGAFAVFGVLALVAFGVVYRYAPETKGRQLEEI
MSMEG_6711|M.smegmatis_MC2_155 GTVLVAFG------MHYQQVFLTLLIPVAVCIAAVVTKGRKARTAGRAQT
TH_2446|M.thermoresistible__bu ILTALIA--------AAGGAPWLACGYLVATALISVVATTALRPAPLHRL
MLBr_01562|M.leprae_Br4923 VKFMNDAQLRALDHGYTYGLLWVAGAVVIVGVAALFIGYTPEQVAYAQEV
MMAR_2574|M.marinum_M ALPLTVADAEDDDEPADGAGARGAQHPGS
MAV_3053|M.avium_104 ALPLTVDDAEDTEPQGDSAPVD-------
Mflv_3055|M.gilvum_PYR-GCK HGEILHGDKSATG----------------
Mvan_3472|M.vanbaalenii_PYR-1 HGEILHADKTATG----------------
MAB_0692c|M.abscessus_ATCC_199 DSAIS------------------------
Mb0805c|M.bovis_AF2122/97 VVSTLIPAAFLPKQQASHRRAPLLSA---
Rv0783c|M.tuberculosis_H37Rv VVSTLIPAAFLPKQQASHRRAPLLSA---
MUL_1444|M.ulcerans_Agy99 RHFWENGGRWPEKLTEAP-----------
MSMEG_6711|M.smegmatis_MC2_155 ASPRSTEAQLPA-----------------
TH_2446|M.thermoresistible__bu -----------------------------
MLBr_01562|M.leprae_Br4923 KEAVDAGEL--------------------