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M. tuberculosis H37Rv Rv0783c (emrB)

annotation: POSSIBLE MULTIDRUG RESISTANCE INTEGRAL MEMBRANE EFFLUX PROTEIN EMRB
coordinates: 876818 - 878440
length: 540

LGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVA
DFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQ
GFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLPVGLSAL
VLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSW
YRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMP
IAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLA
PHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAAVDPSSLPRQTN
FAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0783cemrB-100% (540)POSSIBLE MULTIDRUG RESISTANCE INTEGRAL MEMBRANE EFFLUX PROTEIN EMRB
M. tuberculosis H37RvRv3239c-6e-4729.85% (412) transmembrane transport protein
M. tuberculosis H37RvRv1250-8e-4728.63% (475) drug-transport integral membrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0805cemrB0.0100.00% (540) multidrug resistance integral membrane efflux protein EmrB
M. gilvum PYR-GCKMflv_2221-3e-5128.91% (467) EmrB/QacA family drug resistance transporter
M. leprae Br4923MLBr_01562-5e-3527.61% (460) putative transmembrane efflux protein
M. abscessus ATCC 19977MAB_0945-2e-5434.47% (409) EmrB/QacA family drug resistance transporter
M. marinum MMMAR_4905-0.067.42% (534) integral membrane drug efflux protein
M. avium 104MAV_0730-0.066.48% (534) EmrB efflux protein
M. smegmatis MC2 155MSMEG_5046-3e-5330.15% (461) drug transporter
M. thermoresistible (build 8)TH_3965-3e-5329.86% (489) PUTATIVE drug transporter
M. ulcerans Agy99MUL_0501-0.066.67% (534) integral membrane drug efflux protein
M. vanbaalenii PYR-1Mvan_4474-1e-5030.12% (405) EmrB/QacA family drug resistance transporter

CLUSTAL 2.0.9 multiple sequence alignment


Rv0783c|M.tuberculosis_H37Rv        ----------------------MLGNAMVEACPAEGDAPVPITPAGRPRS
Mb0805c|M.bovis_AF2122/97           ----------------------MLGNAMVEACPAEGDAPVPITPAGRPRS
MMAR_4905|M.marinum_M               ----------------------MLSTAMDEAHCTPAEVAPPDTRTGTSSP
MUL_0501|M.ulcerans_Agy99           ----------------------MLSTAMDEAHCTPAEVAPPDTRTGTSSP
MAV_0730|M.avium_104                MRSPSAITELAAAGAGESGLFDMLSNAMDEAPYAAAKTP-PHAPTGQPGA
Mflv_2221|M.gilvum_PYR-GCK          ----------------------------------MFDTVTSRAAGT----
Mvan_4474|M.vanbaalenii_PYR-1       ----------------------------------MFETVTARVRG-----
MSMEG_5046|M.smegmatis_MC2_155      ----------------------------------MPSSLNARIAGLLPSR
TH_3965|M.thermoresistible__bu      ------------------------VTSVDAGRSTMSEVFTAYAPRS----
MAB_0945|M.abscessus_ATCC_1997      ----------------------------------MEAAVGALSERR----
MLBr_01562|M.leprae_Br4923          --------MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYP
                                                                            .         

Rv0783c|M.tuberculosis_H37Rv        GQRSYPDRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQA
Mb0805c|M.bovis_AF2122/97           GQRSYPDRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQA
MMAR_4905|M.marinum_M               GEHVYPDRLDAGLLRIAGVCVLASLMSVLDATVVGVAQRTFIIEFDSTQA
MUL_0501|M.ulcerans_Agy99           GEHVYPDRLDAGLLRIAGVCVLASLMSVLDATVVGIAQRTFIIEFDSTQA
MAV_0730|M.avium_104                TEREYPDKLDAALLRISGVCILATVMAILDVTVVSVAQRTFIDQFSSSQA
Mflv_2221|M.gilvum_PYR-GCK          ----------TNPWPALWALLIGFFMILVDATIVAVANPAIMASLNAGYD
Mvan_4474|M.vanbaalenii_PYR-1       ----------ADPWPALWALLIGFFMILVDATIVPVANPAIMAQLGADYD
MSMEG_5046|M.smegmatis_MC2_155      VGALRPQDGTGNPWNALWAMMFGFFMILVDATIVSVANPTIMVELGADYD
TH_3965|M.thermoresistible__bu      --------AAANPWHALWAMLIGFFMILVDATIVPVANLEIMADLGADYT
MAB_0945|M.abscessus_ATCC_1997      ------------KIVILGSCCLSLLIVSMDSTIVNVALPTIRADFGATTS
MLBr_01562|M.leprae_Br4923          TLLPSGRFPSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSDA
                                                            .:  :* *:. :*   :  .:.    

Rv0783c|M.tuberculosis_H37Rv        VVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVA
Mb0805c|M.bovis_AF2122/97           VVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVA
MMAR_4905|M.marinum_M               VVAWTMTGYTLALATVIPVAGWAADRFGTKRLWMGSVLAFALGSLLCALA
MUL_0501|M.ulcerans_Agy99           VVAWTMTGYTLALATVIPVAGWAADRFGTKRLWMGSVLAFALGSLLCALA
MAV_0730|M.avium_104                VVAWTMTGYTLALATVIPITGWAADRFGTKRLFIGSVVAFMLGSLLCALA
Mflv_2221|M.gilvum_PYR-GCK          AVIWVTSAYLLAYAVPLLVSGRLGDRYGPKNVYMVGLTVFTVASLWCGLS
Mvan_4474|M.vanbaalenii_PYR-1       AVIWVTSAYLLAYAVPLLVSGRLGDRYGPKTVYLVGLAVFTAASLWCGLS
MSMEG_5046|M.smegmatis_MC2_155      GVIWVTSAYLLAYAVPLLVTGRLGDMYGPKNLYLLGLGVFTAASLWCGLA
TH_3965|M.thermoresistible__bu      AVIWVTSAYLLAYAVPLLIAGRLGDRFGPRTMYLIGLAIFTAASLWCGLA
MAB_0945|M.abscessus_ATCC_1997      QLQWVIDIYTLGLASLLMLSGAAGDRLGRRKVFHLGLSIFAIGSLLCSVA
MLBr_01562|M.leprae_Br4923          GRSWGITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVA
                                       *    * *  .  :   *  .*  * :  :  .:  *  .*: *.::

Rv0783c|M.tuberculosis_H37Rv        PNILLLIIFRVVQGFGGGMLTPVSFAILAREAG-PKRLGRVMAVVGIPML
Mb0805c|M.bovis_AF2122/97           PNILLLIIFRVVQGFGGGMLTPVSFAILAREAG-PKRLGRVMAVVGIPML
MMAR_4905|M.marinum_M               PNILSLIFFRVLQGVGGGMLMPLGFIILTRAAG-PKRLGRLMAAIGIPML
MUL_0501|M.ulcerans_Agy99           PNILSLIFFRVLQGVGGGMLMPLGFIILTRAAG-PKRLGRLMAAIGIPML
MAV_0730|M.avium_104                ANILQLIVFRVVQGIGGGMLLPLGFMILTREAG-PRRLGRLMSILSIPML
Mflv_2221|M.gilvum_PYR-GCK          DSIGMLIAARVVQGVGAALLTPQTMTVITRTFP-AHRRGVAMSVWGATAG
Mvan_4474|M.vanbaalenii_PYR-1       DSIGMLVAARVLQGVGAALLTPQTLTVITRTFP-AHNRGVAMSVWGATAG
MSMEG_5046|M.smegmatis_MC2_155      GSIEMLIAARVVQGIGAALLTPQTLSAITRIFP-ANRRGVAMSVWGATAG
TH_3965|M.thermoresistible__bu      GTIGMLIAARVLQGLGAALLTPQTLSMITRIFP-ADRRGVPMGVWGATAG
MAB_0945|M.abscessus_ATCC_1997      PTVGLLIAARLLQAVGGSMLNPVALSIISQVFTGRVERARALGFWGAVVG
MLBr_01562|M.leprae_Br4923          WDEVTLVIARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTA
                                         *:  *::*..*..:  *  :  ::             .  .    

Rv0783c|M.tuberculosis_H37Rv        LGPVGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASE
Mb0805c|M.bovis_AF2122/97           LGPVGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASE
MMAR_4905|M.marinum_M               LGPIGGPILGGWLISSFGWHWIFLVNLPIGLAAFALAAITFPADRPVPSE
MUL_0501|M.ulcerans_Agy99           LGPIGGPILGGWLISSFGWHWIFLVNLPIGLAAFALAAITFPADRPVPSE
MAV_0730|M.avium_104                LAPIAGPILGGWLIDTSSWRWIFLINVPIGLLTVALAAVVFPRDHPARSE
Mflv_2221|M.gilvum_PYR-GCK          VATLVGPLAGGVLVDSLGWQWIFIVNVPVGIVGLVMALRLVPALPNPVRQ
Mvan_4474|M.vanbaalenii_PYR-1       VATLAGPLAGGVLVDSLGWQWIFIVNLPVGVLGFALAVWLVPSLPTARAQ
MSMEG_5046|M.smegmatis_MC2_155      VATLVGPLAGGVLVGGLGWQWIFFVNVPVGIVGIALAVWLVPTLPTTRHH
TH_3965|M.thermoresistible__bu      VATLIGPLAGGVLVDGLGWQWIFIVNVPIGIAGLVLGARLMPRLP-RQDQ
MAB_0945|M.abscessus_ATCC_1997      ISMALGPIVGGLLIQWVGWRAVFWINLPVCVLAFVLTAVFVPETKSATMR
MLBr_01562|M.leprae_Br4923          IGSVMGLVVGGALTEVS-WRLAFLVNVPIGLVMIYLARTALHETHKERMK
                                    :.   * : ** *     *:  * :*:*: :  . :    .        .

Rv0783c|M.tuberculosis_H37Rv        NFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFV
Mb0805c|M.bovis_AF2122/97           NFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFV
MMAR_4905|M.marinum_M               SFDVIGVLLLSPGLAAFLLGLSLIPDRGTVADRYVLIPVIAGLSLIGGFA
MUL_0501|M.ulcerans_Agy99           SFDVIGVLLLSPGLAAFLLALSLIPDRGTVADRYVLIPVIAGLSLIGGFA
MAV_0730|M.avium_104                TFDAVGVLLLSPGLATFLFAVSSIPGRGTVADRHVLIPAAMGLTLIAGFV
Mflv_2221|M.gilvum_PYR-GCK          GFDVPGVVLSGVGLFLIVFALQ--EGQSHGWALWIWATVLAGVAVMAAFV
Mvan_4474|M.vanbaalenii_PYR-1       RFDLPGVVLSGVALFLIVFALQ--EGQSHDWAPWIWATIGIGIAVMAAFL
MSMEG_5046|M.smegmatis_MC2_155      -FDIPGIVLSAVGMFLIVFALQ--EGQSKDWAPWVWGTATLGVGVMAAFF
TH_3965|M.thermoresistible__bu      GFDVLGMVLSAVGLFLIVFALQ--EAQTHRWAPWIWGTLAGGAGVMAMFV
MAB_0945|M.abscessus_ATCC_1997      DIDPVGQALAVLFLFGIVFALIEGPSLG-WATPGLIVVLAVALAAFAVFL
MLBr_01562|M.leprae_Br4923          -LDAAGAILATLACTAAVFAFSMGPEKGWISLTTIGSGLVALVAAIA--F
                                     :*  *  *        ::..             :          :.   

Rv0783c|M.tuberculosis_H37Rv        AHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQV
Mb0805c|M.bovis_AF2122/97           AHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQV
MMAR_4905|M.marinum_M               WHAWHRADHPLIDLHLFNNSVVTQANLTLLAFAAAYFGSSLLIPTYLQQV
MUL_0501|M.ulcerans_Agy99           WHAWHRADHPLIDLHLFNNSVVTQANLTLLAFAAAYFGSSLLIPTYLQQV
MAV_0730|M.avium_104                GHAWHRADHPLIDLRLFRNPVLTHANVTMLVFATAFFGAGLLLPSYFQQV
Mflv_2221|M.gilvum_PYR-GCK          YWQSINTAGALIPLVIFRDRNFSMSNLGVATIGFVATGMILPLMFFAQAV
Mvan_4474|M.vanbaalenii_PYR-1       YWQSVNTGEPLIPLIIFGDRNFSMSNLGVATIGFVATGMILPLMFYAQSV
MSMEG_5046|M.smegmatis_MC2_155      FWQSVNTREPLIPLRVFADRDFTLANIGVAVIGFAVTAMILPLMFYLQTV
TH_3965|M.thermoresistible__bu      IWQSANRRHPLVPLQIFADRNFMLANVGVATIGFVVTAMVLPAMFFAQAV
MAB_0945|M.abscessus_ATCC_1997      RYESR-RRHPFIDLRFFRSIPFASATLTAICACMAWSAFLFTMSLYLQGQ
MLBr_01562|M.leprae_Br4923          AVVERTAENPVVPFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLYIQDI
                                             ..: : .* .     : :          .  .    : *  

Rv0783c|M.tuberculosis_H37Rv        LHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGL
Mb0805c|M.bovis_AF2122/97           LHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGL
MMAR_4905|M.marinum_M               LHQTPMQSGLYLIPQGLGAMLTMPIASAFMDRRGPGKSVLLGIVLIAVGL
MUL_0501|M.ulcerans_Agy99           LHQTPMQSGLYLIPQGLGAMLTMPIASAFMDRRGPGKSVLLGIVLIAVGL
MAV_0730|M.avium_104                LHQTPMQAGVHMIPQGLGAMLTMRLTGPLVDRQGPGKVVLVGIALITAGL
Mflv_2221|M.gilvum_PYR-GCK          CGLTPTRAALLTAPMAVATGVLAPFVGKLVDRAHPRSVVGFGFSLMAIGV
Mvan_4474|M.vanbaalenii_PYR-1       CGLTPTQAALLTAPMAVATGVLAPLVGKLVDRSHPRPVVGFGFALMAIGL
MSMEG_5046|M.smegmatis_MC2_155      CGLSPIRSALVTAPTAIASGVLAPFVGRIVDRVHPMPVIGFGFSAMAIGL
TH_3965|M.thermoresistible__bu      CGLSPTGSALLIAPMAVASGVLAPMAGRIVDRSHPTPVVGFGFSVVAVGL
MAB_0945|M.abscessus_ATCC_1997      RHFSAMHTGLIYLPIAVGALVFSPISGRMVGRFGARPSLLAAGTLFLT-A
MLBr_01562|M.leprae_Br4923          LGYSALRAGIGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLLMVAM
                                       :.  :.:   *  :.  :   . . ::.*  .      .   .    

Rv0783c|M.tuberculosis_H37Rv        GTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIAR
Mb0805c|M.bovis_AF2122/97           GTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIAR
MMAR_4905|M.marinum_M               AMFTFGVATRAQYLPTLLVGLAIMGMGTGCTMMPLAGAAVLTLKPREIAR
MUL_0501|M.ulcerans_Agy99           AMFTFGVATRAQYLPTLLVGLAIMGMGTGCTMMPLAGAAVLTLKPREIAR
MAV_0730|M.avium_104                GAFAFGVARQAPYLPTLLAGLAITGLGMGCTMMPLSVASVQALAPHQIAR
Mflv_2221|M.gilvum_PYR-GCK          TWLSIEMTPTTPIWRLLLP-LTAMGAAMAFIWSPLAATATRNLPPHLAGA
Mvan_4474|M.vanbaalenii_PYR-1       TWLSIEMTPSTPIWRLVVP-LTAMGVAMAFIWSPLAATATRNLPPQLAGA
MSMEG_5046|M.smegmatis_MC2_155      TWLSIEMAPTTPIWRLLLP-QLLMGIGMAFIWSPLAATATRHLPPDLAGA
TH_3965|M.thermoresistible__bu      TWLAVEMAPTTPIWRLVLP-FVAVGVGMAFIWSPLATTATRQLPLHLSGA
MAB_0945|M.abscessus_ATCC_1997      SLLLTRVSEATPIWELLVT-FAIFGAGFAMVNAPITNAAVSGMPLDRAGA
MLBr_01562|M.leprae_Br4923          LYGWAFMNRGVPYFPNLLAPIVVGGIGIGMAVVPLTLSAIAGVGFDRIGP
                                          :   .     :       * . .    *:: ::   :     . 

Rv0783c|M.tuberculosis_H37Rv        GSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGR
Mb0805c|M.bovis_AF2122/97           GSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGR
MMAR_4905|M.marinum_M               GSTLISVTQQVGGSIGTALMATILTNQFNRSDNIWVANKVATLEQNAAAR
MUL_0501|M.ulcerans_Agy99           GSTLISVTQQVGGSIGTALMATILTNQFNRSDNIWVANKVATLEQNAAAR
MAV_0730|M.avium_104                GTTLMSVSHQVGGSMGTALMSMILTNQFNRSPNIVAANKLAALHQKAAAG
Mflv_2221|M.gilvum_PYR-GCK          GSGVYNTTRQVGSVLGSAGMAALMSSELS--------TKIPG---ADAVP
Mvan_4474|M.vanbaalenii_PYR-1       GSGVYNTTRQVGSVLGSAAMAALLASQLS--------AKIPG---EAPVP
MSMEG_5046|M.smegmatis_MC2_155      GSGVYNTTRQVGSVLGSAGIAAFMTWRIT--------DEVPGMQDAAPAG
TH_3965|M.thermoresistible__bu      GSGVYNTTRQIGSVLGSAGMAAFLTGRLS--------AELPFG--ATAVP
MAB_0945|M.abscessus_ATCC_1997      ASAVTSTSRQVGVSIGVALCGSIGT---------------PALWFMCAGL
MLBr_01562|M.leprae_Br4923          VSAIALMLQSLGGPLVLAVIQAVITSR------------------TLYLG
                                     : :    :.:*  :  *    . :                         

Rv0783c|M.tuberculosis_H37Rv        GAAVDPSSLPRQTN---FAAQLLHDLSHAYAVVFVIATALVVSTLIPAAF
Mb0805c|M.bovis_AF2122/97           GAAVDPSSLPRQTN---FAAQLLHDLSHAYAVVFVIATALVVSTLIPAAF
MMAR_4905|M.marinum_M               GVTVDPSGLPPQALTPDFADNVMHDLSHAYTVVFGVAVVLVVSTLIPAAF
MUL_0501|M.ulcerans_Agy99           GVTVDPSGLPPQALTPDFADNVMHDLSHAYTVVFGVVVVLVVSTLIPAAS
MAV_0730|M.avium_104                GTPIDQSAIPRQSLAPGFGGNVLHDLSHAYTAVFVIAVALVVCTIIPASF
Mflv_2221|M.gilvum_PYR-GCK          QSEGEVAALPQFLREPFALAMSQSMLLPAFVALFGVIAALFLFDLLGDRD
Mvan_4474|M.vanbaalenii_PYR-1       -VEGQAGQLPAFLHAPFAAAMSQAMLLPAFVALFGVIAALFLVG-LGDRL
MSMEG_5046|M.smegmatis_MC2_155      ESGGAVEQLPEFLREPFSAAMSQAMLLPAFIALFGVVAALFLLGFGSNRA
TH_3965|M.thermoresistible__bu      -AGEQTRVLPEFLHAPYAAAMAQSMLLPAFVALFGVLAAIFLAG----IV
MAB_0945|M.abscessus_ATCC_1997      GLLIATLGIVSTSPAAVRSAQRLAPLIEGTTAREMSRVG-----------
MLBr_01562|M.leprae_Br4923          GTTGPVKFMNDAQLRALDHGYTYGLLWVAGAVVIVGVAALFIGYTPEQVA
                                            :                *  .  .     .            

Rv0783c|M.tuberculosis_H37Rv        LPKQ--------------QASHRRAPLLSA--------------------
Mb0805c|M.bovis_AF2122/97           LPKQ--------------QASHRRAPLLSA--------------------
MMAR_4905|M.marinum_M               LPKT--------------PAAAPASF------------------------
MUL_0501|M.ulcerans_Agy99           LPKT--------------PAAAPASFEQHHCDTQYGVHRV----------
MAV_0730|M.avium_104                LPKK--------------PAAETAGK------------------------
Mflv_2221|M.gilvum_PYR-GCK          AAAP--PAPDVEPLEPFDPDHPLDWADGEDDYVEYEVSREE---FDRLAT
Mvan_4474|M.vanbaalenii_PYR-1       PAPPRRPQETAEPVPAFDPDDELYWADGEDEYVEYEVPWDDGAEPRRPAQ
MSMEG_5046|M.smegmatis_MC2_155      AGHP-------------EPEHAGDYPD-DDEYVEIILSSDP---------
TH_3965|M.thermoresistible__bu      LSTP-------------QPDADAQYLDEHDDYLVIELARPD---------
MAB_0945|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_01562|M.leprae_Br4923          YAQE--------------VKEAVDAGEL----------------------
                                                                                      

Rv0783c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0805c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_4905|M.marinum_M               --------------------------------------------------
MUL_0501|M.ulcerans_Agy99           --------------------------------------------------
MAV_0730|M.avium_104                --------------------------------------------------
Mflv_2221|M.gilvum_PYR-GCK          DG-TADGAAYN-ITEDFTEDITD-----VLDTVVEAPPAPADSTPSQQWR
Mvan_4474|M.vanbaalenii_PYR-1       EADTVDAAADTDVLDPVTEPMHDGGGYPAPESAPRRDHADPTSHPDREWR
MSMEG_5046|M.smegmatis_MC2_155      ------------------------------------PEDPPTDPQDDRWQ
TH_3965|M.thermoresistible__bu      --------------------------------PNPRTDIAVTAVIPALRP
MAB_0945|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0783c|M.tuberculosis_H37Rv        -------------------------------------------
Mb0805c|M.bovis_AF2122/97           -------------------------------------------
MMAR_4905|M.marinum_M               -------------------------------------------
MUL_0501|M.ulcerans_Agy99           -------------------------------------------
MAV_0730|M.avium_104                -------------------------------------------
Mflv_2221|M.gilvum_PYR-GCK          DLVDQLLDVSSPPGAP----RNGVGSADAEHPGGGPRV-----
Mvan_4474|M.vanbaalenii_PYR-1       SILDQLLDPPKPSDDPTGQGRNGFHVTPSEDGRGASRGRHSLD
MSMEG_5046|M.smegmatis_MC2_155      HILDRLMQ-DAPPEDP-------------LPGRGPQRR-----
TH_3965|M.thermoresistible__bu      TLRPTLRPSLGPPGGP----------VVQPNNTAALR------
MAB_0945|M.abscessus_ATCC_1997      -------------------------------------------
MLBr_01562|M.leprae_Br4923          -------------------------------------------