For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MAGNTSVPGATVGSRLLAVLDCFDVDHRELTLTEIAQRADLPLSTARRLITELTEWGGLERLSSGGYRIG VRLWQVGSLAPQARNLREAALPHMHDLFEATRENVQLAVLDGLEALCLEKITGTKSVPTVTHVGGRLPLH TTGVGKVLLAFSPRTLLETVVAQGLERSTIHSITEPGRLASALERVRQTGLAYSYEEMTLGAISVASPII HAGRLSGAVSIVTHSGTHLDRLAPAVRTAALGISRSLL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6705 | - | - | 100% (248) | regulatory protein |
| M. smegmatis MC2 155 | MSMEG_2600 | - | 2e-49 | 48.75% (240) | regulatory protein |
| M. smegmatis MC2 155 | MSMEG_2890 | - | 1e-34 | 38.84% (242) | putative transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1748 | - | 8e-14 | 28.71% (209) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_0531 | - | 8e-38 | 42.13% (216) | regulatory protein, IclR |
| M. tuberculosis H37Rv | Rv1719 | - | 8e-14 | 28.71% (209) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0077 | - | 1e-30 | 36.11% (252) | IclR family transcriptional regulator |
| M. marinum M | MMAR_4423 | - | 4e-16 | 29.60% (250) | transcriptional regulatory protein |
| M. avium 104 | MAV_3024 | - | 5e-29 | 38.55% (249) | transcriptional regulator, IclR family protein |
| M. thermoresistible (build 8) | TH_3251 | - | 6e-32 | 37.86% (243) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_1967 | - | 1e-08 | 29.65% (199) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0559 | - | 2e-50 | 45.20% (250) | regulatory proteins, IclR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1748|M.bovis_AF2122/97 --------------MSAEEQDTRSGGIQVIARAAELLRVLQAHPGGLSQA
Rv1719|M.tuberculosis_H37Rv --------------MSAEEQDTRSGGIQVIARAAELLRVLQAHPGGLSQA
Mflv_0531|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0559|M.vanbaalenii_PYR-1 -----------------MAGNTSTPGTTVTSRLLNILGAFDERHKNLTLS
MSMEG_6705|M.smegmatis_MC2_155 -----------------MAGNTSVPGATVGSRLLAVLDCFDVDHRELTLT
MAB_0077|M.abscessus_ATCC_1997 ----------------MTITADSATPSAVIDRVSLLLDAFDGPGR-LTLA
MAV_3024|M.avium_104 ------------------MPAPAETPTAVIDRISLVLDAFDGPGR-LTLA
TH_3251|M.thermoresistible__bu MTATLDQPTPNTTVKRTGTERTGETPSAVLDRISLVLDAFDGPGR-LTLA
MUL_1967|M.ulcerans_Agy99 --------------------MRQDSGIGVIDKAVGLLRAT--AKSPCGLA
MMAR_4423|M.marinum_M MSSGISSMIMGTGNDGGASESDPAPTVQSVDRALLVLELLADLGK-AGVT
Mb1748|M.bovis_AF2122/97 EIGERVGMARSTVSRILNALEDEGLVASRGARGPYRLGPEITRMATTVRL
Rv1719|M.tuberculosis_H37Rv EIGERVGMARSTVSRILNALEDEGLVASRGARGPYRLGPEITRMATTVRL
Mflv_0531|M.gilvum_PYR-GCK -MARRAGLPIATTHRLAAELVAGSALQ-RRADGQYVVGRLVWNAGLLAPV
Mvan_0559|M.vanbaalenii_PYR-1 ELARRAGLPIATTHRLAAELVAGSALQ-RRADGQYVVGRLIWNAGLLAPV
MSMEG_6705|M.smegmatis_MC2_155 EIAQRADLPLSTARRLITELTEWGGLE-RLSSGGYRIGVRLWQVGSLAPQ
MAB_0077|M.abscessus_ATCC_1997 QLVRRTGLPRSSVHRMLERLVQLRWLR-RDGR-DYELGTRLVELGSLAVH
MAV_3024|M.avium_104 QIVRRTGLPRSSAHRMLERLVQLRWLR-RSGR-DYELGMRLVELGSLAVH
TH_3251|M.thermoresistible__bu QVVRRTGLPRSSAHRMLERLVQLRWLR-RDGR-DYELGMRLVELGSLAVH
MUL_1967|M.ulcerans_Agy99 ELCERTGLPRATAYRLAAALEVHRLLG-RDEDGRWGLGPAITELAAHVDD
MMAR_4423|M.marinum_M EVADELGVHKSTASRLITALEARGYVEQLSDRGKYQLGIGVSRLARARSG
: . .: ::. *: * : : :* : . .
Mb1748|M.bovis_AF2122/97 G--VVTEMHPFLTELSRELDETVDLSILDGDRADVVDQVVPPQRLRAVSA
Rv1719|M.tuberculosis_H37Rv G--VVTEMHPFLTELSRELDETVDLSILDGDRADVVDQVVPPQRLRAVSA
Mflv_0531|M.gilvum_PYR-GCK EGQLRQVAEPFLYDVYAATLATVHLAVRDGDEVLYLERMMGRTSVPIVSA
Mvan_0559|M.vanbaalenii_PYR-1 EGQLRQVAEPFLHDVYAATLATVHLAVRDGDEVLYLERMMGRTSVPIVSA
MSMEG_6705|M.smegmatis_MC2_155 ARNLREAALPHMHDLFEATRENVQLAVLDGLEALCLEKITGTKSVPTVTH
MAB_0077|M.abscessus_ATCC_1997 QDRLHAAALPMLHELHRATGLVVHLSILDGADVVYLEKIGAGIGAAVATR
MAV_3024|M.avium_104 QDRLVRAATPLLVELHRATGLVVHLAVLDGPDVVYLEKVGDRLNSVIPSR
TH_3251|M.thermoresistible__bu QDRLHRAAIPRLHELHAATGLVVHLAVLDGSDVVYLEKVGSRLAAAIPTR
MUL_1967|M.ulcerans_Agy99 P--LLTAGATVLPRLCETTGESVQLYRREGTSRVCVAALEPPAGLRDTVP
MMAR_4423|M.marinum_M HSDLVKLSQDACDKLAADLGETANLAILDENRAVNIVEAVSTAEIALQTW
: : ..* : :
Mb1748|M.bovis_AF2122/97 VGESFPLYCCANGKALLAALPPERQARALPSRLAPLTANTITDRAALRDE
Rv1719|M.tuberculosis_H37Rv VGESFPLYCCANGKALLAALPPERQARALPSRLAPLTANTITDRAALRDE
Mflv_0531|M.gilvum_PYR-GCK VGSRLPMHCTGVGKVLLAHAPEDVKDRVFAT-LTRITPYTIVSPTVLSSQ
Mvan_0559|M.vanbaalenii_PYR-1 VGSRLPMHCTGVGKVLLAHAPEDVKHRVFAT-LTRITPYTIVSPTVLSSQ
MSMEG_6705|M.smegmatis_MC2_155 VGGRLPLHTTGVGKVLLAFSPRTLLETVVAQGLERSTIHSITEPGRLASA
MAB_0077|M.abscessus_ATCC_1997 IGGRQPAHCTASGKAILAYR---AQILDGCTALARKTRYSIGSAAQLRPE
MAV_3024|M.avium_104 VGGRQPAHCTAVGKAILAYR---DEATD-LDLGARPTKYSISSAPQLAAE
TH_3251|M.thermoresistible__bu VGGRRPANCAAVGKAILAYAED-DGVLSGTGPLPRNTKYSISDPARLRAE
MUL_1967|M.ulcerans_Agy99 VGARLPMTAGSGAKVLLAHSDP------------ATQQAVLPTAKFTDRV
MMAR_4423|M.marinum_M VGQSCPVHATSSGKVLLAGLDADEVRQRVGATLDSFTENTIVTIDALEAQ
:* * . .*.:** :
Mb1748|M.bovis_AF2122/97 LNRIRVDGVAYDREEQTEGICAVGAVLRGVS-VELVAVSVPVPAQRFYGR
Rv1719|M.tuberculosis_H37Rv LNRIRVDGVAYDREEQTEGICAVGAVLRGVS-VELVAVSVPVPAQRFYGR
Mflv_0531|M.gilvum_PYR-GCK MQRIHREGVATTSEEMSLGACSLAVPVIRQTDDAVVAAIAVVVPTLKRDR
Mvan_0559|M.vanbaalenii_PYR-1 MQRIHREGVATTSEEMSLGACSLAVPVIRQTDDAVVAAIAVVVPTLKRDR
MSMEG_6705|M.smegmatis_MC2_155 LERVRQTGLAYSYEEMTLGAISVASPIIHAG--RLSGAVSIVTHSG-THL
MAB_0077|M.abscessus_ATCC_1997 LDKVRGHGVAFDREELQQGIGCVAAPIGSIG--DAVAAVSVCGPMTRMTF
MAV_3024|M.avium_104 LAKVRAHGVAFEREESLLGFGCVAAPIGGPG--EAAAAVSVCGPLQRMAL
TH_3251|M.thermoresistible__bu LAKVRAHGVAFDREESLPGIGCVAAPIGDPG--EAVAAISVCGPMNQMAF
MUL_1967|M.ulcerans_Agy99 LAEVRRRGWAQSVAEREPGVASVSAPVRDGR-GVVVAAISVSGPIDRIGR
MMAR_4423|M.marinum_M LAATRAAGWASAREELEIGLNAVAAPVYDST-GRVAAALSVSGPAYRLPA
: : * * * * .:. : ..
Mb1748|M.bovis_AF2122/97 --EAELAGALLAWVSKVDAWFNGTEDRK----------------------
Rv1719|M.tuberculosis_H37Rv --EAELAGALLAWVSKVDAWFNGTEDRK----------------------
Mflv_0531|M.gilvum_PYR-GCK --QR-LLGALQVAARGIGRLL-----------------------------
Mvan_0559|M.vanbaalenii_PYR-1 --QR-LLGALQVAARGIGRLL-----------------------------
MSMEG_6705|M.smegmatis_MC2_155 --DR-LAPAVRTAALGISRSLL----------------------------
MAB_0077|M.abscessus_ATCC_1997 --DQRLAAPVRMTAMGIWRNVENGPSRVAPTLQPIRPLRCGPAASSTG-R
MAV_3024|M.avium_104 --DQRLAAPVRMTAMGVWRNVEGGPQRVAPTLQRLRPLP--PMRPQHP-V
TH_3251|M.thermoresistible__bu --DHRLVAPVRMAALGIWRAMEGARQRVVPTLQQVRPLRPGPTAQSLSHS
MUL_1967|M.ulcerans_Agy99 RPGARWAADLLAAADELARRL-----------------------------
MMAR_4423|M.marinum_M ADFEEVAQQTIAAADAVSRGLGWTDRIS----------------------
. : .
Mb1748|M.bovis_AF2122/97 ----------------------
Rv1719|M.tuberculosis_H37Rv ----------------------
Mflv_0531|M.gilvum_PYR-GCK ----------------------
Mvan_0559|M.vanbaalenii_PYR-1 ----------------------
MSMEG_6705|M.smegmatis_MC2_155 ----------------------
MAB_0077|M.abscessus_ATCC_1997 EMNSPALQYA------------
MAV_3024|M.avium_104 PKPRPALQYA------------
TH_3251|M.thermoresistible__bu ALSHPAQSHPARSHRADTRRFA
MUL_1967|M.ulcerans_Agy99 ----------------------
MMAR_4423|M.marinum_M ----------------------