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RQTHIGGVDLNLLPALAALLEERQVSRAAARVGLSQPAMSRALQRLRRTFDDALLVAGRDGYTLTPRAER LQARLAGLMPELDVLFGPENFEPGTATESYRLALSDYSVALFGADLARTIHQRSPGSSVVYQQLDDEAFA ELNAGGIDLLVVGRPAASHLAHRELFTDHFVCAVAHEHPLAARPQVTLQDYLAYPHIRIEIEQGTTHLIE DALPVPRKVAVSTPFYTFAVDMLAGTDLVVTFPARLVAKLANPSAVRILDAPKSFPQLPFYAVWHPRLDH DASHLWLRSTLYELTA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6674 | - | - | 100% (297) | transcriptional regulator, LysR family protein |
| M. smegmatis MC2 155 | MSMEG_5000 | - | 6e-24 | 29.37% (286) | transcriptional regulator, LysR family protein |
| M. smegmatis MC2 155 | MSMEG_0104 | - | 1e-08 | 26.86% (242) | transcriptional regulator, LysR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1833 | - | 2e-11 | 23.27% (202) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_02663 | oxyS | 6e-06 | 36.62% (71) | putative LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4400c | - | 1e-29 | 31.31% (297) | LysR family transcriptional regulator |
| M. marinum M | MMAR_0317 | oxyS | 6e-05 | 35.21% (71) | oxidative stress response regulatory protein OxyS |
| M. avium 104 | MAV_3102 | - | 8e-13 | 25.64% (234) | LysR substrate binding domain-containing protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_4805 | oxyS | 7e-05 | 35.21% (71) | oxidative stress response regulatory protein OxyS |
| M. vanbaalenii PYR-1 | Mvan_3362 | - | 2e-11 | 28.24% (216) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0317|M.marinum_M MKLLGAPKINPELTLAQIPGSDSLVVIPIPRTSGLARRAAPAVQPRCGVT
MUL_4805|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02663|M.leprae_Br4923 --------------------------------------------------
Mflv_1833|M.gilvum_PYR-GCK --------------------------------------------------
MAV_3102|M.avium_104 --------------------------------------------------
Mvan_3362|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6674|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4400c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0317|M.marinum_M RTAQWRADLVATVQDLAAQSGTGGRQRSGGGGSLSESVPMTEEVSVLFRQ
MUL_4805|M.ulcerans_Agy99 ---------------------------------------------MLFRQ
MLBr_02663|M.leprae_Br4923 ---------------------------------------------MLFRQ
Mflv_1833|M.gilvum_PYR-GCK ---------------------------------------------MDTHR
MAV_3102|M.avium_104 ---------------------------------------------MDTHR
Mvan_3362|M.vanbaalenii_PYR-1 ---------------------------------------------MELRQ
MSMEG_6674|M.smegmatis_MC2_155 -------------------------------------MRQTHIGGVDLNL
MAB_4400c|M.abscessus_ATCC_199 ---------------------------------------------MDLNL
: .
MMAR_0317|M.marinum_M LEYFVAVAQERHFARAAEKCYVSQPALSSAIAKLERELNVTLINRGHSFE
MUL_4805|M.ulcerans_Agy99 LEYFVAVAQERHFARAAEKCYVSQPALSSAIAKLERELHVTLINRGHSFE
MLBr_02663|M.leprae_Br4923 LEYFVAVAQERHFARAAERCYVSQPALSSAIAKLERELNVTLINRGHSFE
Mflv_1833|M.gilvum_PYR-GCK LKYFLRIAEEGSITRAASLLGMAQPALSRQLQLLEEDLGVALFRRNRRGV
MAV_3102|M.avium_104 LKYFLRIAEQGSITGAAASLGIAQPALSRQIRLLEEDLGVALFRRTRRGV
Mvan_3362|M.vanbaalenii_PYR-1 LEYLVAVVEERSFTKAAQRERVAQPAVSAQIRRLERQVGQPLLTRSHRGV
MSMEG_6674|M.smegmatis_MC2_155 LPALAALLEERQVSRAAARVGLSQPAMSRALQRLRRTFDDALLVAGRDGY
MAB_4400c|M.abscessus_ATCC_199 LRVLDALLQENSVTAAAERLATSPPAVSRSLGRLRRITGDALLVRAGQGL
* : : :: .: ** : **:* : *.. .*:
MMAR_0317|M.marinum_M GLTPEGERLVVWAKRIIAEHDAFKAE-VDAVRSGITGTLRLGTVP-SAST
MUL_4805|M.ulcerans_Agy99 GLTPEGERLVVWAKRIIAEHDAFKAE-VDAVRSGITGTLRLGTVR-SAST
MLBr_02663|M.leprae_Br4923 GLTPEGERLVVWAKRILAEHDAFKAE-VHAVRSGITGTLRLGTVP-TAST
Mflv_1833|M.gilvum_PYR-GCK ELTDAGERLRSSTAAPLRQLELAVQY-AAFPLARLKRAMLIGIPESAIDV
MAV_3102|M.avium_104 QLTEEGERLRASTAAPLRQLELAMQY-AGSPIARLARGVRLGILDTTVDV
Mvan_3362|M.vanbaalenii_PYR-1 RVTPAGAALLPHARAALAAVRDAQAA-VDDVANLVRGAVAIGTVT-LHPV
MSMEG_6674|M.smegmatis_MC2_155 TLTPRAERLQARLAGLMPELDVLFGP-ENFEPGTATESYRLALSDYSVAL
MAB_4400c|M.abscessus_ATCC_199 VPTPRAVQIRDELGGLLRRADQILRPGAEFDPGKLQRTFIVQAAELFLTA
* . : : :
MMAR_0317|M.marinum_M TASLVLSDFCSAHPLVKAQICSRLAVTELYRRLRDFELDAAIVYT-SSDD
MUL_4805|M.ulcerans_Agy99 TASLVLSDFCSAHPLVKAQICSRLAVTELYRRLRDFERDAAIVYT-SSDD
MLBr_02663|M.leprae_Br4923 TASLVLSAFCSEHPLIKVQICSRLPVTELHRRLGDFELDAVIVHS-APDD
Mflv_1833|M.gilvum_PYR-GCK LAAPLMTRLGSAFPDAQFAVTVG-STDHLVEAMLKGSVDIALINP-VPDD
MAV_3102|M.avium_104 FAAHLLSSLAAAFPKVTFSVETG-STDQLVEAMLKGAVDVAVINP-VPDD
Mvan_3362|M.vanbaalenii_PYR-1 DVARLMADFHAEHPGVEITLGTD-TSDVLLAKLEDGRLDAAIVSIGADED
MSMEG_6674|M.smegmatis_MC2_155 FGADLARTIHQRSPGS--SVVYQQLDDEAFAELNAGGIDLLVVGR---PA
MAB_4400c|M.abscessus_ATCC_199 LAVPLLERLRHDAPGVNVVFAPEAREDTGALRRGDIDIELGSLDH----L
: : * . : :
MMAR_0317|M.marinum_M GHDVDLVPLYEERYVLLAPPEMLPPGVSTLSWLDAAQLPLALLSSDMRDR
MUL_4805|M.ulcerans_Agy99 GHDVDLVPLYEERYVLLAPPEMLPPGVSTLSWLDAAQLPLALLSSDMRDR
MLBr_02663|M.leprae_Br4923 THAVDLVPLYHEHYVLVSPADMLPPGASVLAWPEASQLPLALLTPDMRDR
Mflv_1833|M.gilvum_PYR-GCK --RVFYREILTEEFVLVGGPDSPLEPEKPLQFADLVELPLVVPRSTTGLG
MAV_3102|M.avium_104 --RIFYRDLLTEDLVVVGAATSGLDSGQMMPFTELVELPLVVPRSHTGIG
Mvan_3362|M.vanbaalenii_PYR-1 PAGLEYEVITDEALEAAVTAQHRLARRKSLSLKQLCEYPVISLPAGTGLR
MSMEG_6674|M.smegmatis_MC2_155 ASHLAHRELFTDHFVCAVAHEHPLAARPQVTLQDYLAYPHIRIEIEQGTT
MAB_4400c|M.abscessus_ATCC_199 DPETRHTPVAMLPMVGVAAQDHPLFEGP-IDAGTFATYGHISVSRRGKLY
: :
MMAR_0317|M.marinum_M QIIDAAFADHAITVSPQVETDSVASLFAQVATGNSASIVPHTWLWTTPAG
MUL_4805|M.ulcerans_Agy99 QIIDAAFADHAITVSPQVETDSVASLFAQVATGNSASIVPHTWLWTTPGR
MLBr_02663|M.leprae_Br4923 QLIDRAFAGHAITATPQVETDSVASLFAQVATGNWACIVPHTWLWTTPIG
Mflv_1833|M.gilvum_PYR-GCK QALYNAALRAKVTIDYRITTDSTRVMVCLIESGLAYGVLPLSACGREFAE
MAV_3102|M.avium_104 NVIENAALRRKVKISWRIATDSLALTKRLVAAGLVYGVLPLSACLNEIDS
Mvan_3362|M.vanbaalenii_PYR-1 SRLDDACAAAGLRPRIAFEATSPLELADLARHGLGVAILPRSMARGSAGL
MSMEG_6674|M.smegmatis_MC2_155 HLIEDALP---VPRKVAVSTPFYTFAVDMLAGTDLVVTFPARLVAKLANP
MAB_4400c|M.abscessus_ATCC_199 GPIDEALARHGLRRRVPVVVPSHTSAMLLARSSRLIALTVAGSVDTAGLG
: * : . .
MMAR_0317|M.marinum_M GEIRPVQLVSPVVKAQVALATSS-----TGPGSPVARALMTSAQGLALDE
MUL_4805|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02663|M.leprae_Br4923 AEIRAVEMVDPVLKADVALATNS-----AGPGSPVARALVASAKQLALNE
Mflv_1833|M.gilvum_PYR-GCK SRLRYSRICEPVLTQQLGVAATEQLDLPRELVVKVGNALREEIAALIRSG
MAV_3102|M.avium_104 NQLRYTPLTEPPLTHRVGVAATSNLELPREVTAKVGNILREETAHLIKTG
Mvan_3362|M.vanbaalenii_PYR-1 HPLR----LSPELRGRLVWAWRT------DISGPAARLLNARARAMIAAT
MSMEG_6674|M.smegmatis_MC2_155 SAVRILDAPKSFPQLPFYAVWHP-------------RLDHDASHLWLRST
MAB_4400c|M.abscessus_ATCC_199 --IRMFDIPLELPAVAVGVAWHP-------------RNNDDAAHTWLRGL
MMAR_0317|M.marinum_M FFQTRLMEISRRR----
MUL_4805|M.ulcerans_Agy99 -----------------
MLBr_02663|M.leprae_Br4923 FFEAQLAGITRRR----
Mflv_1833|M.gilvum_PYR-GCK SWRADLLSPEPWSPRRV
MAV_3102|M.avium_104 RWPARLLSPQPWDPAVT
Mvan_3362|M.vanbaalenii_PYR-1 GTPAVIPGA--------
MSMEG_6674|M.smegmatis_MC2_155 LYELTA-----------
MAB_4400c|M.abscessus_ATCC_199 LIESFARLPV-------