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VGMDIGGTVRERAARELRDRILTGALPAGTRIDLDAITAEFATSRTPVREALLELSFEGLVRVAPRSGIT VIGISSADVLDSFTILGVLTGQAAAWAAERVTDEELDQLRALAAGVAEHSGDDAIGEANWRFHQAIHRAA HSPRLLAAIKQAARVVPTNFLVLFPEHEKHSLSEHEELLDALEKRDADHARVIAEHHVLEAGRSLADWLD RRNDHRSGSLPTAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6639 | - | - | 100% (225) | transcriptional regulator, GntR family protein, putative |
| M. smegmatis MC2 155 | MSMEG_2209 | - | 7e-26 | 35.29% (204) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_1995 | - | 1e-22 | 32.00% (200) | transcriptional regulator MdcY family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0170c | - | 4e-22 | 33.68% (193) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4366 | - | 2e-24 | 35.58% (208) | GntR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0043c | - | 3e-17 | 26.92% (182) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4571 | - | 9e-23 | 34.48% (203) | GntR family transcriptional regulatory protein |
| M. marinum M | MMAR_4029 | - | 8e-22 | 33.66% (202) | GntR family transcriptional regulator |
| M. avium 104 | MAV_0339 | - | 1e-93 | 80.00% (215) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_3342 | - | 4e-25 | 34.16% (202) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_3894 | - | 5e-22 | 33.66% (202) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1978 | - | 5e-26 | 36.59% (205) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6639|M.smegmatis_MC2_155 -----------------------------------------MVGMDIG--
MAV_0339|M.avium_104 -----------------------------------------MAAIDIS--
MMAR_4029|M.marinum_M -----------------------------------------MT--DPEFA
MUL_3894|M.ulcerans_Agy99 -----------------------------------------MT--DPEFA
TH_3342|M.thermoresistible__bu -----------------------------------------VA--VPEFA
Mflv_4366|M.gilvum_PYR-GCK -----------------------------------------MT--TPEFA
Mvan_1978|M.vanbaalenii_PYR-1 -----------------------------------------MS--IPEFA
Mb0170c|M.bovis_AF2122/97 MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVN--APLSA
MAB_4571|M.abscessus_ATCC_1997 -----------------------------------------MN--APR-A
Rv0043c|M.tuberculosis_H37Rv ---------------------------------------------MPKKY
MSMEG_6639|M.smegmatis_MC2_155 ----------GTVRERAARELRDRILTGALPAGTRIDLDAITAEFATSRT
MAV_0339|M.avium_104 ----------GTVRERAARELRDRILTGALPAGSRIDLDAITAEFATSRT
MMAR_4029|M.marinum_M --------ARPQLSDDVARYVRKRIYEGNYAAGKYIRLDQLAAELGISVT
MUL_3894|M.ulcerans_Agy99 --------ARPQLSDDVARYVRKRIYEGNYAAGKYIRLDQLAAELGISVT
TH_3342|M.thermoresistible__bu --------ARPQLAEDVARYVRRRIFDGTYAAGEYVRLDQLAVELGVSVT
Mflv_4366|M.gilvum_PYR-GCK --------ARPQLAEDVARFVRRRIFDGTYPAGRYIRLEQLAAELGISVT
Mvan_1978|M.vanbaalenii_PYR-1 --------ARPQLAEDVARFVRRRIFEGTYPAGQYIRLEQLADELGISVT
Mb0170c|M.bovis_AF2122/97 KPRSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVT
MAB_4571|M.abscessus_ATCC_1997 RTR---EIRRPQLSEEVAGRLRAAIMTGDLRPGEYIRMDETAAQLGVSVT
Rv0043c|M.tuberculosis_H37Rv G---------VKEKDQVVAHILNLLLTGKLRSGDRVDRNEIAHGLGVSRV
: .. : : * .* : : : :. * .
MSMEG_6639|M.smegmatis_MC2_155 PVREALLELSFEGLVRVAPRSGITVIGISSADVLDSFTILGVLTGQAAAW
MAV_0339|M.avium_104 PVREALLELSFEGLVQVAPRSGVTVIGISPEDVLDSFTILGVLTGQAAAW
MMAR_4029|M.marinum_M PVREALFALRAEGLVAQQPHRGFVVLPLTKRDLADVAYVQAHVGGELAAR
MUL_3894|M.ulcerans_Agy99 PVREALFALRAEGLVAQQPHRGFVVLPLTKRDLADVAYVQAHVGGELAAR
TH_3342|M.thermoresistible__bu PVREALFQLRAEGLLVQQPRRGFMVLPVTERDLTDIANVQAHVGGELAAR
Mflv_4366|M.gilvum_PYR-GCK PVREALFGLRAEGLLTQQPRRGFVVSPITERDIADVSDVQAHIGGVLASR
Mvan_1978|M.vanbaalenii_PYR-1 PVREALFGLRAEGLLTQQPRRGFVVLPITRRDIADVADVQAHIGGVLASR
Mb0170c|M.bovis_AF2122/97 PVREALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATS
MAB_4571|M.abscessus_ATCC_1997 PVREALLTLRGEGMVDAVPHRGYAVAALSRKDVEDIFALQSHLAVELAKA
Rv0043c|M.tuberculosis_H37Rv PIQEALVQLEHDGIVSTRYHRGAFIERFDVATILEHHELDGLLNGIASAR
*::***. * :*:: : * : . : : : . : :
MSMEG_6639|M.smegmatis_MC2_155 AAERVTDEELDQLRALAAGVAEHSGD---DAIGEANWRFHQAIHRAAHSP
MAV_0339|M.avium_104 AAERIGPEELATLRELAAEVVAKSGD---DSIGEANWHFHQMIHRAAHSP
MMAR_4029|M.marinum_M AAINIGAAQLAELQQIQAQLEEAYAADDDERTVRLNHEFHRAINLAADSP
MUL_3894|M.ulcerans_Agy99 AAINIGAAQLAELQQIQAQLEEAYAADDDERTVRLNHEFHRAINLAADSP
TH_3342|M.thermoresistible__bu AAQNITDEQLRVLTAIQDELEEAYTRDDEDRAVRLNHEFHRAINVAADSP
Mflv_4366|M.gilvum_PYR-GCK AAELITDEQLAELERIQDELEAAYDAVDHEAAVRLNHAFHRGVNIAAGSP
Mvan_1978|M.vanbaalenii_PYR-1 AAERITDEQLQALDHVQDQLEVAYHADDHEAAVRLNHEFHRGVNVAAGSP
Mb0170c|M.bovis_AF2122/97 ATAHITDVEIDELDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASRRI
MAB_4571|M.abscessus_ATCC_1997 AAARITPEQADALAELNDALRNATSP---DQVIWAEFEFHRLLNHVADRP
Rv0043c|M.tuberculosis_H37Rv AAANPTPRILGQLDAVMRSLRNSKES---RAFAECVWEYRRTVNDEYAGP
*: * : : ::: .:
MSMEG_6639|M.smegmatis_MC2_155 RLLAAIKQAARVVPTNFLVLFPEHEKHSLSEHEELLDALEKRDADHARVI
MAV_0339|M.avium_104 RLANQIKHAARVVPTNFLTLFPEHEKHSLDEHAQLLDALGDKDVERARAI
MMAR_4029|M.marinum_M RLSQLMSQITRYQPESVFPGIEHWPARAVKDHRRVLVALKKHDDKAARTA
MUL_3894|M.ulcerans_Agy99 RLSQLMSQITRYQPESVFPGIEHWPARAVKDHGQVLVALKKHDDKAARTA
TH_3342|M.thermoresistible__bu KLAQVMSQITRYAPESVFPTISGWPARSTEHHRRVLAALADRDPDGARAA
Mflv_4366|M.gilvum_PYR-GCK KLAQLMGQITRFALESVYPTVEGWPAHSMNDHRVLLAALRKRDGTAARDA
Mvan_1978|M.vanbaalenii_PYR-1 KLAQLMGQITKFALESVYPTVEGWPAHSTRDHRELLAALKARDSEAARAA
Mb0170c|M.bovis_AF2122/97 KLAWFLLNAARYMPAQVFAADPRWGADAVNSHRQLIAALRRRDTAAVIEH
MAB_4571|M.abscessus_ATCC_1997 KLAWFLLQAVRYTPHQLFAEDASWIVPTTETHDKLIAALRAGDIAEVIAQ
Rv0043c|M.tuberculosis_H37Rv RLHATIRASQNLIPRVFWMTYQNSRDDVLPFYEEENAAIHRREPEAARAA
:* : . . : *: : .
MSMEG_6639|M.smegmatis_MC2_155 AEHHVLEAGRSLADWLDRRNDHRSGSLPTAR-------------------
MAV_0339|M.avium_104 AERHVLDAGRSLAEWLEQRRDGER--------------------------
MMAR_4029|M.marinum_M MSEHLASSAVPLIDHLIARGVVAESAPSGSAAERARGG------------
MUL_3894|M.ulcerans_Agy99 MSEHLASSAVPLIDHLIARGVVAESAPSGSAAERARGG------------
TH_3342|M.thermoresistible__bu MSEHLAAGAGPLIEHLKEHGVIAQ--------------------------
Mflv_4366|M.gilvum_PYR-GCK MSEHLCAAAGPLIDHLTTRGVIG---------------------------
Mvan_1978|M.vanbaalenii_PYR-1 MSEHLCAASGPLIEHLTRRGVIQ---------------------------
Mb0170c|M.bovis_AF2122/97 TVWQFTDGARRLTEALAETEVFG---------------------------
MAB_4571|M.abscessus_ATCC_1997 TEVQFIDGARRLIEYLDRTGMWSQD-------------------------
Rv0043c|M.tuberculosis_H37Rv CIGRSELMAQTMLAELFRRRVLVPPEGACPGPFGAPIPGFARSYQPSSPV
: . : *
MSMEG_6639|M.smegmatis_MC2_155 -
MAV_0339|M.avium_104 -
MMAR_4029|M.marinum_M -
MUL_3894|M.ulcerans_Agy99 -
TH_3342|M.thermoresistible__bu -
Mflv_4366|M.gilvum_PYR-GCK -
Mvan_1978|M.vanbaalenii_PYR-1 -
Mb0170c|M.bovis_AF2122/97 -
MAB_4571|M.abscessus_ATCC_1997 -
Rv0043c|M.tuberculosis_H37Rv P