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M. smegmatis MC2 155 MSMEG_1995 (-)

annotation: transcriptional regulator MdcY family protein
coordinates: 2076671 - 2077354
length: 227

RPTAATDRKRTPPLRLSDLAAAHVRELIVSGQLRAGEFIRPETVADDLGISATPAREGLLLLQTEGFLTI
EPRKGFSVTALSSEDIRDVYDAQALLGGELTARAAGVITAELVEELENIQAQLEQAAAGKDYDDVERLNH
RFHQTIYRLSGSRKIRWLIKATLPYAPRKFFAAVEGWPEASAHDHRAIIEKLRSGDAEGAREAMAQHIRR
AGTLLAEHLAASGTLG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_1995--100% (227)transcriptional regulator MdcY family protein
M. smegmatis MC2 155MSMEG_2209-7e-4445.50% (211) transcriptional regulator, GntR family protein
M. smegmatis MC2 155MSMEG_0130-9e-3135.90% (195) transcriptional regulator, GntR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0170c-5e-3033.92% (227) GntR family transcriptional regulator
M. gilvum PYR-GCKMflv_4366-3e-4242.45% (212) GntR family transcriptional regulator
M. tuberculosis H37RvRv0165c-3e-2436.22% (196) GntR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4571-1e-2734.08% (223) GntR family transcriptional regulatory protein
M. marinum MMMAR_4029-2e-4040.00% (220) GntR family transcriptional regulator
M. avium 104MAV_1576-1e-4342.65% (211) transcriptional regulator, GntR family protein
M. thermoresistible (build 8)TH_3342-9e-4039.34% (211) PUTATIVE transcriptional regulator, GntR family
M. ulcerans Agy99MUL_3894-1e-3939.55% (220) GntR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_1978-5e-4242.18% (211) GntR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4029|M.marinum_M               -----------------------------------------MTDPEFAAR
MUL_3894|M.ulcerans_Agy99           -----------------------------------------MTDPEFAAR
MAV_1576|M.avium_104                -----------------------------------------MSVPDFAAR
TH_3342|M.thermoresistible__bu      -----------------------------------------VAVPEFAAR
Mflv_4366|M.gilvum_PYR-GCK          -----------------------------------------MTTPEFAAR
Mvan_1978|M.vanbaalenii_PYR-1       -----------------------------------------MSIPEFAAR
MSMEG_1995|M.smegmatis_MC2_155      -----------------------------------------MRPTAATDR
Mb0170c|M.bovis_AF2122/97           MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
Rv0165c|M.tuberculosis_H37Rv        MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
MAB_4571|M.abscessus_ATCC_1997      -----------------------------------------MNAPR-ART
                                                                             :  .  :  

MMAR_4029|M.marinum_M               P--------QLSDDVARYVRKRIYEGNYAAGKYIRLDQLAAELGISVTPV
MUL_3894|M.ulcerans_Agy99           P--------QLSDDVARYVRKRIYEGNYAAGKYIRLDQLAAELGISVTPV
MAV_1576|M.avium_104                P--------QLSDDVAHLIRGRIFDGSYAAGSYVRLDQLAAELGISVTPV
TH_3342|M.thermoresistible__bu      P--------QLAEDVARYVRRRIFDGTYAAGEYVRLDQLAVELGVSVTPV
Mflv_4366|M.gilvum_PYR-GCK          P--------QLAEDVARFVRRRIFDGTYPAGRYIRLEQLAAELGISVTPV
Mvan_1978|M.vanbaalenii_PYR-1       P--------QLAEDVARFVRRRIFEGTYPAGQYIRLEQLADELGISVTPV
MSMEG_1995|M.smegmatis_MC2_155      KR---TPPLRLSDLAAAHVRELIVSGQLRAGEFIRPETVADDLGISATPA
Mb0170c|M.bovis_AF2122/97           RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
Rv0165c|M.tuberculosis_H37Rv        RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
MAB_4571|M.abscessus_ATCC_1997      R---EIRRPQLSEEVAGRLRAAIMTGDLRPGEYIRMDETAAQLGVSVTPV
                                             :*:: .*  :*  *  *   .* ::* :  * :**:*.**.

MMAR_4029|M.marinum_M               REALFALRAEGLVAQQPHRGFVVLPLTKRDLADVAYVQAHVGGELAARAA
MUL_3894|M.ulcerans_Agy99           REALFALRAEGLVAQQPHRGFVVLPLTKRDLADVAYVQAHVGGELAARAA
MAV_1576|M.avium_104                REALFALRAEGLISQQPRRGFVVLPVTRRDVTDVANVQAHVGGELAARAA
TH_3342|M.thermoresistible__bu      REALFQLRAEGLLVQQPRRGFMVLPVTERDLTDIANVQAHVGGELAARAA
Mflv_4366|M.gilvum_PYR-GCK          REALFGLRAEGLLTQQPRRGFVVSPITERDIADVSDVQAHIGGVLASRAA
Mvan_1978|M.vanbaalenii_PYR-1       REALFGLRAEGLLTQQPRRGFVVLPITRRDIADVADVQAHIGGVLASRAA
MSMEG_1995|M.smegmatis_MC2_155      REGLLLLQTEGFLTIEPRKGFSVTALSSEDIRDVYDAQALLGGELTARAA
Mb0170c|M.bovis_AF2122/97           REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSAT
Rv0165c|M.tuberculosis_H37Rv        REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSAT
MAB_4571|M.abscessus_ATCC_1997      REALLTLRGEGMVDAVPHRGYAVAALSRKDVEDIFALQSHLAVELAKAAA
                                    **.*: *: **::   *::*. * .:: .*: *:   *: :.  *:  *:

MMAR_4029|M.marinum_M               INIGAAQLAELQQIQAQLEEAYAADDDERTVRLNHEFHRAINLAADSPRL
MUL_3894|M.ulcerans_Agy99           INIGAAQLAELQQIQAQLEEAYAADDDERTVRLNHEFHRAINLAADSPRL
MAV_1576|M.avium_104                VNITDDQLRELKQIQAQLEDAYAGDEHERTVRLNHEFHRAINIAADSPKL
TH_3342|M.thermoresistible__bu      QNITDEQLRVLTAIQDELEEAYTRDDEDRAVRLNHEFHRAINVAADSPKL
Mflv_4366|M.gilvum_PYR-GCK          ELITDEQLAELERIQDELEAAYDAVDHEAAVRLNHAFHRGVNIAAGSPKL
Mvan_1978|M.vanbaalenii_PYR-1       ERITDEQLQALDHVQDQLEVAYHADDHEAAVRLNHEFHRGVNVAAGSPKL
MSMEG_1995|M.smegmatis_MC2_155      GVITAELVEELENIQAQLEQAAAGKDYDDVERLNHRFHQTIYRLSGSRKI
Mb0170c|M.bovis_AF2122/97           AHITDVEIDELDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASRRIKL
Rv0165c|M.tuberculosis_H37Rv        AHITDVEIDELDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASRRIKL
MAB_4571|M.abscessus_ATCC_1997      ARITPEQADALAELNDALRNATSP---DQVIWAEFEFHRLLNHVADRPKL
                                      *       *  ::  *  *      .     :. **: .   :   ::

MMAR_4029|M.marinum_M               SQLMSQITRYQPESVFPGIEHWPARAVKDHRRVLVALKKHDDKAARTAMS
MUL_3894|M.ulcerans_Agy99           SQLMSQITRYQPESVFPGIEHWPARAVKDHGQVLVALKKHDDKAARTAMS
MAV_1576|M.avium_104                AQLMSQITRYAPESVFPAIQGWPEQSMKDHRRILSALKKRDDKLARAAMS
TH_3342|M.thermoresistible__bu      AQVMSQITRYAPESVFPTISGWPARSTEHHRRVLAALADRDPDGARAAMS
Mflv_4366|M.gilvum_PYR-GCK          AQLMGQITRFALESVYPTVEGWPAHSMNDHRVLLAALRKRDGTAARDAMS
Mvan_1978|M.vanbaalenii_PYR-1       AQLMGQITKFALESVYPTVEGWPAHSTRDHRELLAALKARDSEAARAAMS
MSMEG_1995|M.smegmatis_MC2_155      RWLIKATLPYAPRKFFAAVEGWPEASAHDHRAIIEKLRSGDAEGAREAMA
Mb0170c|M.bovis_AF2122/97           AWFLLNAARYMPAQVFAADPRWGADAVNSHRQLIAALRRRDTAAVIEHTV
Rv0165c|M.tuberculosis_H37Rv        AWFLLNAARYMGAGVRGRP----AMGRGRGEQSSAADRR---AAPPRHSR
MAB_4571|M.abscessus_ATCC_1997      AWFLLQAVRYTPHQLFAEDASWIVPTTETHDKLIAALRAGDIAEVIAQTE
                                      .:     :    .                                   

MMAR_4029|M.marinum_M               EHLASSAVPLIDHLIARGVVAESAPSGSAAERARGG
MUL_3894|M.ulcerans_Agy99           EHLASSAVPLIDHLIARGVVAESAPSGSAAERARGG
MAV_1576|M.avium_104                EHLAAGAVPLIDHLVARGVVVD----GGGPDPG---
TH_3342|M.thermoresistible__bu      EHLAAGAGPLIEHLKEHGVIAQ--------------
Mflv_4366|M.gilvum_PYR-GCK          EHLCAAAGPLIDHLTTRGVIG---------------
Mvan_1978|M.vanbaalenii_PYR-1       EHLCAASGPLIEHLTRRGVIQ---------------
MSMEG_1995|M.smegmatis_MC2_155      QHIRRAGTLLAEHLAASGTLG---------------
Mb0170c|M.bovis_AF2122/97           WQFTDGARRLTEALAETEVFG---------------
Rv0165c|M.tuberculosis_H37Rv        R---NRAHRLAVHRWGTQADGGPG------------
MAB_4571|M.abscessus_ATCC_1997      VQFIDGARRLIEYLDRTGMWSQD-------------
                                          .  *