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MSTPTAQRTLAVDGVRSPVFVAGPDGSESTREAVVFVHGNNAGAPWDPLPARVAQFSRVVVPEMPGFGAA DKPAQWPYTVTAYAQHLDGILEQLGVEHAHLVAHDFGGPWALAWAAEHLGAVASITLINAPVVIDHLAAK LWRTPVVAEALWRITPQALMRQALARNDPNLPADAVNRIAAHMVAPGTPDAVLKLYRTTGPDAVAPYADR LAGFDRNVLIMWGTEDRYVPFAQTEQYRQIFAHCEIHAVAGAGHWPWLEQPDTVAGYLTNFLRRLPRKAT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6586 | - | - | 100% (280) | alpha/beta hydrolase, putative |
| M. smegmatis MC2 155 | MSMEG_4860 | - | 1e-16 | 28.98% (283) | hydrolase, alpha/beta fold family protein, putative |
| M. smegmatis MC2 155 | MSMEG_6151 | - | 4e-16 | 26.99% (289) | alpha/beta hydrolase fold-1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2734 | - | 5e-14 | 25.75% (299) | hydrolase |
| M. gilvum PYR-GCK | Mflv_3952 | - | 3e-15 | 24.74% (291) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv2715 | - | 5e-14 | 25.75% (299) | hydrolase |
| M. leprae Br4923 | MLBr_02297 | - | 1e-07 | 23.26% (288) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_2946c | - | 1e-11 | 25.94% (266) | Alpha/beta hydrolase fold |
| M. marinum M | MMAR_1997 | - | 4e-14 | 24.81% (266) | hydrolase |
| M. avium 104 | MAV_3609 | - | 5e-14 | 25.94% (266) | hydrolase |
| M. thermoresistible (build 8) | TH_3479 | - | 1e-11 | 24.81% (262) | PUTATIVE alpha/beta hydrolase fold |
| M. ulcerans Agy99 | MUL_3358 | - | 2e-14 | 24.81% (266) | hydrolase |
| M. vanbaalenii PYR-1 | Mvan_2445 | - | 6e-14 | 24.92% (297) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2734|M.bovis_AF2122/97 ----MTERKRN--LRPVRDVAPPTLQFRTVHGYRRAFRIAG------SGP
Rv2715|M.tuberculosis_H37Rv ----MTERKRN--LRPVRDVAPPTLQFRTVHGYRRAFRIAG------SGP
MMAR_1997|M.marinum_M ----MTERKRN--LRPVREVTAPSLQFRTIHGYKRAFRIAG------SGP
MUL_3358|M.ulcerans_Agy99 ----MTERKRN--LRPVREVTAPSLQFRTIHGYKRAFRIAG------SGP
MAV_3609|M.avium_104 ----MTERKRKNTLRPVREVSAPRLEFRTIHGYRRAYRIAG------SGP
Mflv_3952|M.gilvum_PYR-GCK ----MTARTPN--LRPVRELT-PTLRYCTIHGYRRAYRIAG------SGP
Mvan_2445|M.vanbaalenii_PYR-1 ----MTERKPN--LRPVRELT-PTLKFCTIHGYRRAFRVAG------SGP
MAB_2946c|M.abscessus_ATCC_199 ------------------MIAESRAEYGGVV--TRVLSVPG------GGP
MSMEG_6586|M.smegmatis_MC2_155 ------------------MSTPTAQRTLAVDGVRSPVFVAGPDGSESTRE
MLBr_02297|M.leprae_Br4923 MAMSNPSVTRIAGPWHHLDVHANGIRFHVVEAVPTQPAGQDCAPSATARP
TH_3479|M.thermoresistible__bu ----------------------MSATTITVDDAAIEYTDVG------GGP
: .
Mb2734|M.bovis_AF2122/97 AILLIHGIGDNSTTWNGVHAKLAQR-FTVIAPDLLGHGQSDKPRAD---Y
Rv2715|M.tuberculosis_H37Rv AILLIHGIGDNSTTWNGVHAKLAQR-FTVIAPDLLGHGQSDKPRAD---Y
MMAR_1997|M.marinum_M AILLIHGIGDNSTTWTGIHAKLAQR-FTVIAPDLLGHGRSDKPRAD---Y
MUL_3358|M.ulcerans_Agy99 AILLIHGIGDNSTTWTGIHAKLAQR-FTVIAPDLLGHGRSDKPRAD---Y
MAV_3609|M.avium_104 AILLIHGIGDNSTTWNTVQAKLAQR-FTVIAPDLLGHGQSDKPRAD---Y
Mflv_3952|M.gilvum_PYR-GCK AILLIHGIGDNSTTWAGVQTQLAQR-FTVIAPDLLGHGKSDKPRAD---Y
Mvan_2445|M.vanbaalenii_PYR-1 AILLIHGIGDNSTTWSTVQTQLAQR-FTVIAPDLLGHGRSDKPRAD---Y
MAB_2946c|M.abscessus_ATCC_199 PIVLLHGYSDSALTWRPVLARLASAGRAAIAVDLPGFGHAAPRPPG---P
MSMEG_6586|M.smegmatis_MC2_155 AVVFVHGN-NAGAPWDPLPARVAQF-SRVVVPEMPGFGAADKPAQWP--Y
MLBr_02297|M.leprae_Br4923 LVMLLHGFGSFWWSWRHQLRGLTEA--RLVAVDLRGYGGSDKPPRG---Y
TH_3479|M.thermoresistible__bu PIVFVHGAYVTGALWDDVVTRLSRG-HRCIAPTWP-FGAQRTPVGDSVDL
::::** * :: :. .*
Mb2734|M.bovis_AF2122/97 SVAAYANGMRDLLSVLDIERVTIVGHSLGGGVAMQFAYQF---PQLVDRL
Rv2715|M.tuberculosis_H37Rv SVAAYANGMRDLLSVLDIERVTIVGHSLGGGVAMQFAYQF---PQLVDRL
MMAR_1997|M.marinum_M SIAAYANGMRDLLSVLDIERVTIIGHSLGGGVAMQFAYQF---PQLVDRL
MUL_3358|M.ulcerans_Agy99 SIAAYANGMRDLLSVLDIERVTIIGHSLGGGVAMQFAYQF---PQLVDRL
MAV_3609|M.avium_104 SVAAYANGMRDLLAVLDIERVTIVGHSLGGGVAMQFAYQF---PHLVERL
Mflv_3952|M.gilvum_PYR-GCK SVAAYANGMRDLLSVLNIDSATVVGHSLGGGVAMQFAYQF---PQLVDRL
Mvan_2445|M.vanbaalenii_PYR-1 SVAAYANGMRDLLSVLDIDDVTVIGHSLGGGVAMQFAYQF---PQLVNRL
MAB_2946c|M.abscessus_ATCC_199 LLAQFDVFADAVLAAAG--PAVLVGNSLGAATAVRAAARR---ENEVKAL
MSMEG_6586|M.smegmatis_MC2_155 TVTAYAQHLDGILEQLGVEHAHLVAHDFGGPWALAWAAEH---LGAVASI
MLBr_02297|M.leprae_Br4923 DGWTLAGDTAGLIRALGHSSATLVGHAEGGLACWATALLH---PRLVRAI
TH_3479|M.thermoresistible__bu DVVACGRRIIGLLEQLDLRDVTLVANDSGGGITLSALGILGLDWSRVSRL
:: . . ::.: *. * :
Mb2734|M.bovis_AF2122/97 ILVSAG---GVTKDVNIVFRLASLPMGSEA----MALLRLPLVLPAVQIA
Rv2715|M.tuberculosis_H37Rv ILVSAG---GVTKDVNIVFRLASLPMGSEA----MALLRLPLVLPAVQIA
MMAR_1997|M.marinum_M ILVGAG---GVTKDVNVVFRLASLPMGAEA----LALLRLPMVLPTVQLA
MUL_3358|M.ulcerans_Agy99 ILVGAG---GVTKDVNVVFRLASLPMGAEA----LALLRLPMVLPTVQLA
MAV_3609|M.avium_104 ILVGAG---GVTKDVNFVLRWASLPLGSEA----IALLRLPLVLPAVQLM
Mflv_3952|M.gilvum_PYR-GCK ILVGAG---GVTKDVNIALRAASLPMGTEA----LALLRLPLLLPTLRLL
Mvan_2445|M.vanbaalenii_PYR-1 ILVGAG---GVTKDVNIALRLASLPMGSEA----LALLRLPLVLPALQVL
MAB_2946c|M.abscessus_ATCC_199 IALDDP---LNSRHLIARIVRRWSVPEVFW----AWVSRMPVPAGTLRRA
MSMEG_6586|M.smegmatis_MC2_155 TLINAP---VVIDHLAAKLWRTPVVAEALWRITPQALMRQALARNDPNLP
MLBr_02297|M.leprae_Br4923 ALINSPHPAALRRSMLTHRNQGYALLPTLLRYQLPIWPERLLTRNNAAEI
TH_3479|M.thermoresistible__bu VFTNCDTFEHFPPKQFAPLVKLCRVAPPLG----GAVLRLLATGPGLAFF
. .
Mb2734|M.bovis_AF2122/97 GRIVG-KAIGTTSLGHDLPN---VLRILDDLPEPTASAAFGRTLRAVVDW
Rv2715|M.tuberculosis_H37Rv GRIVG-KAIGTTSLGHDLPN---VLRILDDLPEPTASAAFGRTLRAVVDW
MMAR_1997|M.marinum_M GKVLG-MALGSTALGQDLPN---VLRILDDLPEPTASSAFTRTLRAVVDW
MUL_3358|M.ulcerans_Agy99 GKVLG-MALGSTALGQDLPN---VLRILDDLPEPTASSAFTRTLRAVVDW
MAV_3609|M.avium_104 GRVLG-TALGSTGLGRDLPN---VLRILDDLPEPTASAAFSRTLRAVVDW
Mflv_3952|M.gilvum_PYR-GCK GRVGG-PLLGNTRIGRDIPN---MLRILADLPEPTASSAFARTLRSVVDW
Mvan_2445|M.vanbaalenii_PYR-1 GRVSG-TVFGSTGVGRDIPD---MLRILADLPEPTASSAFARTLRAVVDW
MAB_2946c|M.abscessus_ATCC_199 ARYFVPKMLYGPGVAADPEV---VAYWCELISGPSAVARLGR-----DAC
MSMEG_6586|M.smegmatis_MC2_155 ADAVN--RIAAHMVAPGTPD---AVLKLYRTTGPDAVAPYADRLAG----
MLBr_02297|M.leprae_Br4923 ERLVRSRSSAKWQACEDFAVTIDHLRIAIQIPAAAHCALEYQRWAVRSQL
TH_3479|M.thermoresistible__bu KRAVT-----RNGITGDRDD-----AIFGGFLSSAAVRREAVRFSAG--L
. .
Mb2734|M.bovis_AF2122/97 RGQMVTMLDRCYLTEAIPVQIIWGTKDVVLPVRHAHMAHAAMPGSQLEIF
Rv2715|M.tuberculosis_H37Rv RGQMVTMLDRCYLTEAIPVQIIWGTKDVVLPVRHAHMAHAAMPGSQLEIF
MMAR_1997|M.marinum_M RGQIVTMLDRCYLTQAIPVQIIWGSRDAVVPVRHAEMAHAAMPGSKLEVF
MUL_3358|M.ulcerans_Agy99 RGQIVTMLDRCYLTQAIPVQIIWGSRDAVVPVRHAEMAHAAMPGSKLEVF
MAV_3609|M.avium_104 RGQIVTMLDRCYLTEAIPVQIVWGTKDVVVPVRHAWMAHAAMPGSRLEIF
Mflv_3952|M.gilvum_PYR-GCK RGQVVTMLDRCYLTQSVPVQLIWGSQDSVIPVSHAEMAHTAMPGSRLEIF
Mvan_2445|M.vanbaalenii_PYR-1 RGQVVTMLDRCYLTQSVPVQLIWGDCDAVIPVSHGEMAHAAMPGSRLEVF
MAB_2946c|M.abscessus_ATCC_199 RYAHEALGSHSGIEVSCPTLVVHGGRDRIIPIHSSGALQQQIPGSELVIL
MSMEG_6586|M.smegmatis_MC2_155 --------------FDRNVLIMWGTEDRYVPFAQTEQYRQIFAHCEIHAV
MLBr_02297|M.leprae_Br4923 RNEGRKFMKSMSRPFSVPLLHVRGDADPYLLADSVDRTRRYAPHGRYVSV
TH_3479|M.thermoresistible__bu HPQHTAAAAQAIGKWTKPVLVLWGTADDLFPVSHAQRLAEAFPNSRLRLI
: * * . . . .
Mb2734|M.bovis_AF2122/97 EGSGHFPFHDDPARFIDIVERFMDTTEPAEYDQAALRALLRRGGGEATVT
Rv2715|M.tuberculosis_H37Rv EGSGHFPFHDDPARFIDIVERFMDTTEPAEYDQAALRALLRRGGGEATVT
MMAR_1997|M.marinum_M EGSGHFPFHDDPARFIDIVLRFIDSTQPPEYDQAALRELLRTGGGERTVS
MUL_3358|M.ulcerans_Agy99 EGSGHFPFHDDPARFIDIVLRFIDSTQPPEYDQAALRELLRTGGGERTVS
MAV_3609|M.avium_104 EGSGHFPFHDDPARFIDVVERFIDSTEPAAYDQEALRRLLRSGGGAQAVT
Mflv_3952|M.gilvum_PYR-GCK EGAGHFPFHDEPDRFVELVEKFIDSTEPAVYDQEYLRTLLRTGTSENTLS
Mvan_2445|M.vanbaalenii_PYR-1 EGSGHFPFHDDPDRFVEVVEKFIDTSEPAVYDHEYLRGLLRAGISEGTIS
MAB_2946c|M.abscessus_ATCC_199 PASGHCPQLDNPDEVTRLIVDFCDRISEPRQPDAAHSG------------
MSMEG_6586|M.smegmatis_MC2_155 AGAGHWPWLEQPDTVAGYLTNFLRRLPRKAT-------------------
MLBr_02297|M.leprae_Br4923 SDAGHFSHEEAPEEINRYLTRFLKQVHGPRLS------------------
TH_3479|M.thermoresistible__bu EGSSTYVMLDHPSETADAIGTFIAGRS-----------------------
:. : * : *
Mb2734|M.bovis_AF2122/97 GSADTRVAVLNAIGSNERSAT
Rv2715|M.tuberculosis_H37Rv GSADTRVAVLNAIGSNERSAT
MMAR_1997|M.marinum_M GPADTRVAVLSAMGSDERSAT
MUL_3358|M.ulcerans_Agy99 DPADTRVAVLSAMGSDERSAT
MAV_3609|M.avium_104 GPAPTRVAVLSAMGSDERSAT
Mflv_3952|M.gilvum_PYR-GCK GDVDTQVAVLDAIGADERSAT
Mvan_2445|M.vanbaalenii_PYR-1 GPADTRVAVLDAMGADERSAT
MAB_2946c|M.abscessus_ATCC_199 ---------------------
MSMEG_6586|M.smegmatis_MC2_155 ---------------------
MLBr_02297|M.leprae_Br4923 ---------------------
TH_3479|M.thermoresistible__bu ---------------------