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VSVELVRAPRGLRRVRAVAMRMGAFALVELQKLRHDRTELFTRMVQPALWLLIFGQTFSRLHVVDTGGVP YLAFLAPGIIAQSALFISIFYGIQIIWDRDAGILAKLMVTPAPASALVAGKAFAAGVRSVVQVIGVVALA YLMGIALTLNPLRILAAMGVVVLGAAFFACLSMTLAGLVRKRDRLMGIGQAITMPLFFASNALYPVDIMP TWLRWLSAVNPLSYEVNALRGLLIGTPTNWVLDITVLVAAAVLGVVAASALLRRLVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6510 | - | - | 100% (267) | ABC-type drug export system, membrane protein |
| M. smegmatis MC2 155 | MSMEG_6765 | - | 2e-14 | 25.71% (280) | ABC-2 type transporter superfamily protein |
| M. smegmatis MC2 155 | MSMEG_3763 | - | 4e-10 | 25.88% (170) | ABC transporter efflux protein, DrrB family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2963 | drrC | 4e-12 | 24.72% (267) | daunorubicin-DIM-transport integral membrane protein ABC |
| M. gilvum PYR-GCK | Mflv_1937 | - | 2e-15 | 24.66% (219) | ABC-2 type transporter |
| M. tuberculosis H37Rv | Rv2938 | drrC | 4e-12 | 24.72% (267) | daunorubicin-DIM-transport integral membrane protein ABC |
| M. leprae Br4923 | MLBr_02350 | - | 4e-13 | 24.14% (232) | putative antibiotic resistance membrane protein |
| M. abscessus ATCC 19977 | MAB_1860 | - | 1e-06 | 26.21% (145) | antibiotic ABC transporter membrane protein |
| M. marinum M | MMAR_1769 | drrC | 2e-12 | 25.76% (229) | daunorubicin-DIM-transport integral membrane protein ABC |
| M. avium 104 | MAV_5182 | - | 1e-118 | 82.82% (262) | ABC-type drug export system, membrane protein |
| M. thermoresistible (build 8) | TH_0342 | - | 8e-07 | 28.42% (190) | PROBABLE UNIDENTIFIED ANTIBIOTIC-TRANSPORT INTEGRAL MEMBRANE |
| M. ulcerans Agy99 | MUL_2012 | drrC | 1e-12 | 25.76% (229) | daunorubicin-DIM-transport integral membrane protein ABC |
| M. vanbaalenii PYR-1 | Mvan_4795 | - | 8e-16 | 25.67% (187) | ABC-2 type transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6510|M.smegmatis_MC2_155 --MSVE------LVRAPRGLRRVRAVAMRMGAFALVELQKLRHDRTELFT
MAV_5182|M.avium_104 --MSVDNAAAATLVRAPRGWQRVGALSSRVGAFAIVEIQKLQHDRTELVT
Mb2963|M.bovis_AF2122/97 MITTTSQEIELAPTRLPGSQNAARLFVAQTLLQTNRLLTRWARDYITVIG
Rv2938|M.tuberculosis_H37Rv MITTTSQEIELAPTRLPGSQNAARLFVAQTLLQTNRLLTRWARDYITVIG
MLBr_02350|M.leprae_Br4923 MITMISQTVGLVPASLQYPNNSVRALVSQTLLQTKRLLTRWARDYVTIIG
MMAR_1769|M.marinum_M ---MTSQEIAFAPAQSQHTDHSARLLIWQTLVQTQRILTRWSRDFVTLIE
MUL_2012|M.ulcerans_Agy99 MIGMTSQEIAFAPAQSQHTDHSARLLIWQTLVQTQRILTRWSRDFVTLIE
Mflv_1937|M.gilvum_PYR-GCK --MTAVDSQTHTPVQPRPVPIRPTNLAQQSWIMVKRNMIHTKRMPEMLSD
Mvan_4795|M.vanbaalenii_PYR-1 --MTALDTEAHAAVRPQPVPIRPTNLAQQSWIMVKRNMIHTKRMPEMLSD
MAB_1860|M.abscessus_ATCC_1997 ------------------------MMPIRVWAAFGRNDIRGTYRDPLLIM
TH_0342|M.thermoresistible__bu -------VTNRFPAGTFTPDPRPAPVPRMLAAQYGLELKLLLRNGEQLLL
. :
MSMEG_6510|M.smegmatis_MC2_155 RMVQPALWLLIFGQTFSRLHVVDTGG------VPYLAFLAPGIIAQSALF
MAV_5182|M.avium_104 RMVQPALWLLIFGTTFSHLHMIDTGP------VSYLAFLAPGIIAQSALF
Mb2963|M.bovis_AF2122/97 AIVLPILFMVVLNIVLGNLAYVVTH-------DSGLYSIVPLIALGAAIT
Rv2938|M.tuberculosis_H37Rv AIVLPILFMVVLNIVLGNLAYVVTH-------DSGLYSIVPLIALGAAIT
MLBr_02350|M.leprae_Br4923 ALVLPILFLVVLNIVLGNLAYVVTY-------DSGLYSFVPLITLGAAIT
MMAR_1769|M.marinum_M ALVFPILFMLVLKIVLGNLIYAVTH-------HDAMYSIVPLIALGAAIT
MUL_2012|M.ulcerans_Agy99 ALVFPILFMLVLKIVLGNLIYAVTH-------HDAMYSIVPLIALGAAIT
Mflv_1937|M.gilvum_PYR-GCK VTAQPIMFVLLFAFVFGASITNTGG-------ASYREFLLPGIQAQTIVF
Mvan_4795|M.vanbaalenii_PYR-1 VTAQPIMFVLLFAFVFGASITNTGG-------ASYREFLLPGIQAQTIVF
MAB_1860|M.abscessus_ATCC_1997 VVLAPIIWTTGVAVLTPQATDLLSATRGFDLVPYYPLVLTAFLLLTSIII
TH_0342|M.thermoresistible__bu TLFIPITLLVGLILLPLGDFGDDRAS----------RFVPAIMALAVIST
* . . . :
MSMEG_6510|M.smegmatis_MC2_155 ISIFYGIQIIWDRDAGILAKLMVTPAPASALVAGKAFAAGVRSVVQVIGV
MAV_5182|M.avium_104 ISIFYGIQIIWDRDAGVLAKLMVTPAPASALVTGKAFAAGVRSVAQVVGV
Mb2963|M.bovis_AF2122/97 GSTFVAIDLMRERSFGLLARLWVLPVHRASGLISRILANAIRTLVTTLVM
Rv2938|M.tuberculosis_H37Rv GSTFVAIDLMRERSFGLLARLWVLPVHRASGLISRILANAIRTLVTTLVM
MLBr_02350|M.leprae_Br4923 GSTFVAIDLVRERSIGLLSRLWVLPIHRASGLLARILANTIRTFVTTLVM
MMAR_1769|M.marinum_M GSAFVAIDLMRERTSGLLSRLWVLPVHRMSGLMARILADAVRILFTTLVM
MUL_2012|M.ulcerans_Agy99 GSAFVAIDLMRERTSGLLSRLWVLPVHRMSGLMARILADAVRILFTTLVM
Mflv_1937|M.gilvum_PYR-GCK SAFVVASGITADVEKGIIDRFRSLPISRSSVLIGRSIASVIHSSLGALVM
Mvan_4795|M.vanbaalenii_PYR-1 SAFVVASGITADVEKGIIDRFRSLPISRSSVLIGRSIASVIHSSLGVLVM
MAB_1860|M.abscessus_ATCC_1997 PGALAAFLVLDDVDAGTLTALRVTPVPMSGYFLYRAATVVVITTVYVVAT
TH_0342|M.thermoresistible__bu AFTGQAIAVAFDRRYGALKRLGATALPVWGIIVGKSLAVVTVVFVQSVVL
. : : * : : . . . : : :
MSMEG_6510|M.smegmatis_MC2_155 VALAYLMGIALTLNPLRILAAMGVVVLGAAFFACLSMTLAGLVRKRDRLM
MAV_5182|M.avium_104 LALAYLMRIGLTVNPLRILAAMGIVMLGAAFFACLSMTLAGLVRNRDRLM
Mb2963|M.bovis_AF2122/97 LGTGVVLGFRFRQGLIPSLMWISVPVILGIAIAAMVTTVALYTAQTVVVE
Rv2938|M.tuberculosis_H37Rv LGTGVVLGFRFRQGLIPSLMWISVPVILGIAIAAMVTTVALYTAQTVVVE
MLBr_02350|M.leprae_Br4923 LVTGVILGFRFRQGVIASLMWVSVPVIFGIAIAVMVTTVALYTEQTFVVE
MMAR_1769|M.marinum_M LGVGILMGFEFRQGLIASLMWLCVPVTLGIAFAVMVTTVALYSSQAVIVE
MUL_2012|M.ulcerans_Agy99 LGVGILMGFEFRQGLIASLMWLCVPVTLGIAFAVMVTTVALYSSQAVIVE
Mflv_1937|M.gilvum_PYR-GCK ALTGLAIGWRIRNGVGEAVLAFALLMLFGFGMIWFGILIGSLMRSVEAVN
Mvan_4795|M.vanbaalenii_PYR-1 ALTGLAIGWRIRNGVAEAVLAFALLLLFGFGMIWFGILIGSLLRTVEAVN
MAB_1860|M.abscessus_ATCC_1997 LSLSGILEPGVLP------ALIPIGMLSGLSAVVTLLLVIAFANN--KIQ
TH_0342|M.thermoresistible__bu GAIGAALGWRPQP--AGLLLGAVIIALGTAVFAALGLLLGGTLRAEIVLA
. : : : :
MSMEG_6510|M.smegmatis_MC2_155 GIGQAITMPLFFASNALYP-VDIMPTWLRWLSAVNPLSYEVNALRGLLIG
MAV_5182|M.avium_104 GIGQAITMPLFFASNALYP-VELMPTWLHVLSKINPLSYEVNALRALLIG
Mb2963|M.bovis_AF2122/97 GVELVQAIAI-FFSTGLVP-LNSYPGWIQPFVAHQPVSYAIAAMRGFAMG
Rv2938|M.tuberculosis_H37Rv GVELVQAIAI-FFSTGLVP-LNSYPGWIQPFVAHQPVSYAIAAMRGFAMG
MLBr_02350|M.leprae_Br4923 AVELVQAIAV-FLSTGLVP-LNQYPGWIQPLVAHQPVSYAIAAMRGLSMG
MMAR_1769|M.marinum_M GVELTQAIAI-FFSTGLIP-LDQYPHWIQPVVAHQPVSYAVSAMRGLSMG
MUL_2012|M.ulcerans_Agy99 GVELTQAIAI-FFSTGLIP-LDQYPHWIQPVVAHQPVSYAVSAMRGLSMG
Mflv_1937|M.gilvum_PYR-GCK GVMFTALFPVTFLANTFVP-TEPMPHWLRVIAEWNPVSSLAQAMRELWGN
Mvan_4795|M.vanbaalenii_PYR-1 GVMFTALFPVTFLANTFVP-TEPMPRWLRVIAEWNPVSSLAQAMRELWGN
MAB_1860|M.abscessus_ATCC_1997 GLAAVRALGMLIAGLPCLP-WFIHSNWGYAFGVLPPFWAAKAFWVASAHG
TH_0342|M.thermoresistible__bu VANLLWFVFAAFGALTVEPEGDVVPAAAALVARLTPSGALTDALSQAMTL
. : . * . . *
MSMEG_6510|M.smegmatis_MC2_155 T---------PTNWVLDITVLVAAAVLGVVAASALLRRLVR---
MAV_5182|M.avium_104 T---------PFN-PVDIAVLAAAAVTGILTASTLLRRLVA---
Mb2963|M.bovis_AF2122/97 G---------PVLSPMIGMLVWTAGICVVCAVPLAIGYRRASTH
Rv2938|M.tuberculosis_H37Rv G---------PVLSPMIGMLVWTAGICVVCAVPLAIGYRRASTH
MLBr_02350|M.leprae_Br4923 G---------PVLASMVAMLVWTAGICASCAVPLGVGYRRACTH
MMAR_1769|M.marinum_M G---------PVLLPMIGVLLWTAGICAVCAVPLAVGWRRASTH
MUL_2012|M.ulcerans_Agy99 G---------PVLLPMIGVLLWTAGICAVCAVPLAVGWRRASTH
Mflv_1937|M.gilvum_PYR-GCK GGPAPASAQLPLHYPVASTILWSLALTAVFAPFALYAYKRRTGG
Mvan_4795|M.vanbaalenii_PYR-1 GGPAPAGAQLPLHHPVLATVLWSLALTAVFAPFALYAYKRRTGG
MAB_1860|M.abscessus_ATCC_1997 --------------MWWPFVLIGVAYNLLIAWALLRRFLAKNL-
TH_0342|M.thermoresistible__bu S--------------VNWFAVAVLAVWGVLGAVCALRWFRFT--
: .