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APMVSTRAVRVSGLRLLVATVISVMFTTFAVASLEIPRANAFSREGLPVEYLDVYSPSMGRNLRVQFQGP GETVDDMRPSRAVYLLDGLRAQDDYSGWDINTPAFEWFYNSGISVVMPVGGQSSFYSDWYSPSSFNNQTY TYKWETFLTRELPAWLAANRNVSTTGNGVVGLSMSGSAALILSAFHPGQFRYAASLSGFLNPSSLLMQQA IRVAMLDAGGYNVDNMWGPPWDGAWKRNDPIRQVDRIVANGTRLWIYCAPGGATPLDDGADPNLAMSANS LETLAIKSNKDFQEAYVRAGGRNATFTFPPAGNHAWPYWGAQLSALKPDLIASLNG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6399 | - | - | 100% (337) | antigen 85-C |
| M. smegmatis MC2 155 | MSMEG_3580 | - | e-109 | 59.68% (315) | antigen 85-C |
| M. smegmatis MC2 155 | MSMEG_6583 | - | e-104 | 57.81% (320) | antigen 85-C |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0134c | fbpC | 1e-106 | 62.08% (298) | secreted antigen 85-C FBPC (85C) (antigen 85 complex C) |
| M. gilvum PYR-GCK | Mflv_3335 | - | 1e-107 | 61.64% (292) | putative esterase |
| M. tuberculosis H37Rv | Rv0129c | fbpC | 1e-106 | 62.08% (298) | secreted antigen 85-C FBPC (85C) (antigen 85 complex C) |
| M. leprae Br4923 | MLBr_02655 | fbpC2 | 1e-105 | 56.83% (322) | secreted antigen 85A, mycolyltransferase |
| M. abscessus ATCC 19977 | MAB_0175 | - | 1e-134 | 68.58% (331) | antigen 85-C precursor |
| M. marinum M | MMAR_0328 | fbpC | 1e-107 | 58.39% (322) | secreted antigen 85-C FbpC |
| M. avium 104 | MAV_5183 | - | 1e-108 | 60.13% (316) | antigen 85-C |
| M. thermoresistible (build 8) | TH_2079 | - | 1e-140 | 76.32% (304) | antigen 85-C |
| M. ulcerans Agy99 | MUL_4793 | fbpC | 1e-107 | 58.39% (322) | secreted antigen 85-C FbpC |
| M. vanbaalenii PYR-1 | Mvan_3061 | - | 1e-109 | 62.67% (292) | putative esterase |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_02655|M.leprae_Br4923 MKFLQQMRKLFGLAAKFPARLTIAVIGTALLAGLVGVVGDTAIAVAFSKP
MAV_5183|M.avium_104 MSFIEKVRKLRGAAATMPRRLAIAAVGASLLSGVAVAAGGSPVAGAFSKP
Mb0134c|M.bovis_AF2122/97 MTFFEQVRRLRSAATTLPRRLAIAAMGAVLVYGLVGTFGGPATAGAFSRP
Rv0129c|M.tuberculosis_H37Rv MTFFEQVRRLRSAATTLPRRLAIAAMGAVLVYGLVGTFGGPATAGAFSRP
MMAR_0328|M.marinum_M MKFVEKLR---GAAAGAPRRLTIAAIGAALLSGLVGAVGGAATAGAFSRP
MUL_4793|M.ulcerans_Agy99 MKFVEKLR---GAAAGAPRRLTIAAIGAALLSGLVGAVGGAATAGAFSRP
Mflv_3335|M.gilvum_PYR-GCK MKWKEKAR---GTRKSLVRRVAAAALAAAALPGLIGVAGGSATAGAFSRP
Mvan_3061|M.vanbaalenii_PYR-1 MKLKEKWR---GTARAAMRRVAAAALAAVALPGLIGFAGGSATAGAFSRP
MSMEG_6399|M.smegmatis_MC2_155 MAPMVSTR----AVRVSGLRLLVATVISVMFTTFAVASLEIPRANAFSRE
TH_2079|M.thermoresistible__bu --------------VIAAAALLMLPLSAPALAMVAGT----PSAHAFSRE
MAB_0175|M.abscessus_ATCC_1997 MSVRVKAR----RVLSALLAAFVMPVSMAAAMTINPA-----TAHAFSRE
: . * ***:
MLBr_02655|M.leprae_Br4923 GLPVEYLQVPSPSMGHDIKIQFQ---GGGQ---------HAVYLLDGLRA
MAV_5183|M.avium_104 GLPVEYLEVPSPSMGRNIKVQFQ---GGGP---------HAVYLLDGLRA
Mb0134c|M.bovis_AF2122/97 GLPVEYLQVPSASMGRDIKVQFQ---GGGP---------HAVYLLDGLRA
Rv0129c|M.tuberculosis_H37Rv GLPVEYLQVPSASMGRDIKVQFQ---GGGP---------HAVYLLDGLRA
MMAR_0328|M.marinum_M GLPVEYLQIPSAAMGRDIKVQFQ---GGGA---------HSVYLLDGLRA
MUL_4793|M.ulcerans_Agy99 GLPVEYLQIPSAAMGRDIKVQFQ---GGGA---------HSVYLLDGLRA
Mflv_3335|M.gilvum_PYR-GCK GLPVEYLDVFSPSMNRDIRIQFQ---GGGP---------HAVYLLDGLRA
Mvan_3061|M.vanbaalenii_PYR-1 GLPVEYLDVFSPSMGRDIRVQFQ---GGGP---------RAVYLLDGLRA
MSMEG_6399|M.smegmatis_MC2_155 GLPVEYLDVYSPSMGRNLRVQFQ---GPGETVDDMRP-SRAVYLLDGLRA
TH_2079|M.thermoresistible__bu GLPVEYLDVYSASMGRNIRVQFQPATTPGSDGKEVIAGARAVYMLDGMRA
MAB_0175|M.abscessus_ATCC_1997 GLPVEYLDVYSNSMGRNIRVEFQ---GGGP---------KAVYLLDGLRA
*******:: * :*.::::::** * ::**:***:**
MLBr_02655|M.leprae_Br4923 QEDYNGWDINTPAFEEYYHSGLSVIMPVGGQSSFYSNWYQPSQGNGQHYT
MAV_5183|M.avium_104 QDDYNGWDINTPAFEEFYQSGLSVIMPVGGQSSFYSNWYQPSSGNGQNYT
Mb0134c|M.bovis_AF2122/97 QDDYNGWDINTPAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYT
Rv0129c|M.tuberculosis_H37Rv QDDYNGWDINTPAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYT
MMAR_0328|M.marinum_M QDDYNGWDINTPAFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYT
MUL_4793|M.ulcerans_Agy99 QDDYNGWDINTPAFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYT
Mflv_3335|M.gilvum_PYR-GCK QEDYNGWDINTPAFEWFYQSGLSTIMPVGGQSSFYSDWYQPSRGNGQNYT
Mvan_3061|M.vanbaalenii_PYR-1 QEDYNGWDINTPAFEWFYQSGLSTIMPVGGQSSFYTDWYQPSRGNGQNYT
MSMEG_6399|M.smegmatis_MC2_155 QDDYSGWDINTPAFEWFYNSGISVVMPVGGQSSFYSDWYSPSSFNNQTYT
TH_2079|M.thermoresistible__bu RDDYNGWDIETPAFEWFYDSGIAVVMPVGGQSSFYTDWYSPSNFNKQTYT
MAB_0175|M.abscessus_ATCC_1997 QDDFNGWDINTAAFEWFYQSGISVVMPVGGQSSFYTDWYSPSALNKQPYT
::*:.****:*.*** :*.**::.:**********::**.** * * **
MLBr_02655|M.leprae_Br4923 YKWETFLTQEMPSWLQANKNVLPTGNAAVGLSMSGSSALILASYYPQQFP
MAV_5183|M.avium_104 YKWETFLTQEMPLWMQSNKQVSPAGNAAVGLSMSGGSALILAAYYPQQFP
Mb0134c|M.bovis_AF2122/97 YKWETFLTREMPAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFP
Rv0129c|M.tuberculosis_H37Rv YKWETFLTREMPAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFP
MMAR_0328|M.marinum_M YKWETFLTREMPAWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFP
MUL_4793|M.ulcerans_Agy99 YKWETFLTREMPAWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFP
Mflv_3335|M.gilvum_PYR-GCK YKWETFLTQELPAWLEANRGVSRTGNAVVGLSMAGSASLTYAIHHPQQFI
Mvan_3061|M.vanbaalenii_PYR-1 YKWETFLSQELPAWLEANRGVSRTGNAVVGLSMAGSAALTYAIYHPQQFI
MSMEG_6399|M.smegmatis_MC2_155 YKWETFLTRELPAWLAANRNVSTTGNGVVGLSMSGSAALILSAFHPGQFR
TH_2079|M.thermoresistible__bu YKWETFLTRELPAYLASEKQVSSTGNGVVGLSMSGSSALILAAYYPQQFR
MAB_0175|M.abscessus_ATCC_1997 YKWETFLTQELPAYLATNKQISATGNGVVGLSMSGGAALILAAFHPAQFR
*******::*:* :: ::: : :**..*****:*.::* : .:* **
MLBr_02655|M.leprae_Br4923 YAASLSGFLNPSEGWWPTMIGLAMNDSGGYNANSMWGPSTDPAWKRNDPM
MAV_5183|M.avium_104 YAASLSGFLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDPAWKRNDPM
Mb0134c|M.bovis_AF2122/97 YAASLSGFLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSSDPAWKRNDPM
Rv0129c|M.tuberculosis_H37Rv YAASLSGFLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSSDPAWKRNDPM
MMAR_0328|M.marinum_M YAASLSGFLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDPAWKRNDPM
MUL_4793|M.ulcerans_Agy99 YAASLSGFLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDPAWKRNDPM
Mflv_3335|M.gilvum_PYR-GCK YAASLSGFLNPSEGWWPMLIGLAMNDAGGFNAESMWGPSSDPAWKRNDPM
Mvan_3061|M.vanbaalenii_PYR-1 YAASLSGFLNPSEGWWPMLIGLAMNDAGGFNAESMWGPSSDPAWKRNDPM
MSMEG_6399|M.smegmatis_MC2_155 YAASLSGFLNPSSLLMQQAIRVAMLDAGGYNVDNMWGPPWDGAWKRNDPI
TH_2079|M.thermoresistible__bu YAASLSGYLNPSSTFMKQAIRVAMLDAGGYNVDNMWGPPWNQAWKRNDPV
MAB_0175|M.abscessus_ATCC_1997 FAGSLSGFLNPSTIFMTNAIRVAMLDAGSYSVDNMWGPPWDPAWRRNDPT
:*.****:**** * :** *:*.:..:.****. : **:****
MLBr_02655|M.leprae_Br4923 VQIPRLVANNTRIWVYCGNGAPNELG----GDN-IPAKFLESLTLSTNEI
MAV_5183|M.avium_104 VQIPRLVANNTRIWVYCGNGTPSDLG----GDN-VPAKFLEGLTLRTNEQ
Mb0134c|M.bovis_AF2122/97 VQIPRLVANNTRIWVYCGNGTPSDLG----GDN-IPAKFLEGLTLRTNQT
Rv0129c|M.tuberculosis_H37Rv VQIPRLVANNTRIWVYCGNGTPSDLG----GDN-IPAKFLEGLTLRTNQT
MMAR_0328|M.marinum_M VQIPRLVANNTRIWVYCGNGTPSDLG----GDN-MPAKFLEGLTLRTNQT
MUL_4793|M.ulcerans_Agy99 VQIPRLVANNTRIWVYCGNGTPSDLG----GDN-MPAKFLEGLTLRTNQT
Mflv_3335|M.gilvum_PYR-GCK VNINQLVANNTRIWIYCGTGTPSDLDSGTPGQNLMAAQFLEGFTLRTNVA
Mvan_3061|M.vanbaalenii_PYR-1 VNINQLVANNTRIWIYCGTGTPSDLDNGTPGNNLMAAQFLEGFTLRTNIA
MSMEG_6399|M.smegmatis_MC2_155 RQVDRIVANGTRLWIYCAPGGATPLDDGADPNLAMSANSLETLAIKSNKD
TH_2079|M.thermoresistible__bu EQVERLVNNGTRLWIYCAPGGETELDVNADPNQSFNANSLESMAINGNKK
MAB_0175|M.abscessus_ATCC_1997 VQAQALVAAGTRLYIYCAPGGSTPIDDNTDAGVALSASSLESLAVAGNKA
: :* .**:::**. * . :. . *. ** ::: *
MLBr_02655|M.leprae_Br4923 FQNTYAASGGRNGVFNFPPNGTHSWPYWNQQLVAMKPDIQQILNGSNNNA
MAV_5183|M.avium_104 FQNNYAAAGGRNGVFNFPANGTHSWPYWNQQLMAMKPDMQQVLLSGNTTA
Mb0134c|M.bovis_AF2122/97 FRDTYAADGGRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNGATPPA
Rv0129c|M.tuberculosis_H37Rv FRDTYAADGGRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNGATPPA
MMAR_0328|M.marinum_M FRDTYLASGGRNGVFNFPTNGTHSWPYWNQQLVAMKGDILKVLNGPAVPA
MUL_4793|M.ulcerans_Agy99 FRDTYLASGGRNGVFNFPTNGTHSWPYWNQQLVAMKGDILKVLNGPAVPA
Mflv_3335|M.gilvum_PYR-GCK FRDNYIAAGGNNGVFNFPTSGTHSWGYWGQQLQQMKPDIQRVLGAQATA-
Mvan_3061|M.vanbaalenii_PYR-1 FRDNYIAAGGTNGVFNFPTSGTHSWGYWGQQLQQMKPDIQRVLGAQATV-
MSMEG_6399|M.smegmatis_MC2_155 FQEAYVRAGGRNATFTFPPAGNHAWPYWGAQLSALKPDLIASLNG-----
TH_2079|M.thermoresistible__bu FQEKYVAAGGRNATFNFPPAGNHSWPYWATQLQALKPDLLATLNG-----
MAB_0175|M.abscessus_ATCC_1997 FQQAYTAAGGRNANFVFPASGNHSWPYWGQQLQALKGDLIATLNG-----
*:: * ** *. * **. *.*:* ** ** :* *: * .
MLBr_02655|M.leprae_Br4923 ----------------------
MAV_5183|M.avium_104 APAQPAQPAQPAQPAQPAQPAT
Mb0134c|M.bovis_AF2122/97 APAAPAA---------------
Rv0129c|M.tuberculosis_H37Rv APAAPAA---------------
MMAR_0328|M.marinum_M APAAPEAPAAPVAPAA------
MUL_4793|M.ulcerans_Agy99 APAAPEAPAAPVAPAA------
Mflv_3335|M.gilvum_PYR-GCK ----------------------
Mvan_3061|M.vanbaalenii_PYR-1 ----------------------
MSMEG_6399|M.smegmatis_MC2_155 ----------------------
TH_2079|M.thermoresistible__bu ----------------------
MAB_0175|M.abscessus_ATCC_1997 ----------------------