For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_2079 (-)

annotation: antigen 85-C
coordinates: 4088088 - 4089071
length: 328

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2079--100% (328)antigen 85-C
M. thermoresistible (build 8)TH_1495fbpAe-10157.05% (319) SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A)
M. thermoresistible (build 8)TH_2078fbpAe-10155.21% (326) SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0134cfbpC1e-10560.46% (306) secreted antigen 85-C FBPC (85C) (antigen 85 complex C)
M. gilvum PYR-GCKMflv_3335-1e-10355.69% (325) putative esterase
M. tuberculosis H37RvRv0129cfbpC1e-10560.46% (306) secreted antigen 85-C FBPC (85C) (antigen 85 complex C)
M. leprae Br4923MLBr_02655fbpC21e-10356.52% (322) secreted antigen 85A, mycolyltransferase
M. abscessus ATCC 19977MAB_0175-1e-13168.62% (325) antigen 85-C precursor
M. marinum MMMAR_0328fbpC1e-10559.42% (308) secreted antigen 85-C FbpC
M. avium 104MAV_5183-1e-10558.02% (324) antigen 85-C
M. smegmatis MC2 155MSMEG_6399-1e-14076.32% (304) antigen 85-C
M. ulcerans Agy99MUL_4793fbpC1e-10559.42% (308) secreted antigen 85-C FbpC
M. vanbaalenii PYR-1Mvan_3061-1e-10656.48% (324) putative esterase

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_02655|M.leprae_Br4923          MKFLQQMRKLFGLAAKFPARLTIAVIGTALLAGLVGVVGDTAIAVAFSKP
MAV_5183|M.avium_104                MSFIEKVRKLRGAAATMPRRLAIAAVGASLLSGVAVAAGGSPVAGAFSKP
Mb0134c|M.bovis_AF2122/97           MTFFEQVRRLRSAATTLPRRLAIAAMGAVLVYGLVGTFGGPATAGAFSRP
Rv0129c|M.tuberculosis_H37Rv        MTFFEQVRRLRSAATTLPRRLAIAAMGAVLVYGLVGTFGGPATAGAFSRP
MMAR_0328|M.marinum_M               MKFVEKLR---GAAAGAPRRLTIAAIGAALLSGLVGAVGGAATAGAFSRP
MUL_4793|M.ulcerans_Agy99           MKFVEKLR---GAAAGAPRRLTIAAIGAALLSGLVGAVGGAATAGAFSRP
Mflv_3335|M.gilvum_PYR-GCK          MKWKEKAR---GTRKSLVRRVAAAALAAAALPGLIGVAGGSATAGAFSRP
Mvan_3061|M.vanbaalenii_PYR-1       MKLKEKWR---GTARAAMRRVAAAALAAVALPGLIGFAGGSATAGAFSRP
TH_2079|M.thermoresistible__bu      --------------VIAAAALLMLPLSAPALAMVAGT----PSAHAFSRE
MSMEG_6399|M.smegmatis_MC2_155      MAPMVSTR----AVRVSGLRLLVATVISVMFTTFAVASLEIPRANAFSRE
MAB_0175|M.abscessus_ATCC_1997      MSVRVKAR----RVLSALLAAFVMPVSMAAAMTINPA-----TAHAFSRE
                                                             :       .         * ***: 

MLBr_02655|M.leprae_Br4923          GLPVEYLQVPSPSMGHDIKIQFQ---GGGQ---------HAVYLLDGLRA
MAV_5183|M.avium_104                GLPVEYLEVPSPSMGRNIKVQFQ---GGGP---------HAVYLLDGLRA
Mb0134c|M.bovis_AF2122/97           GLPVEYLQVPSASMGRDIKVQFQ---GGGP---------HAVYLLDGLRA
Rv0129c|M.tuberculosis_H37Rv        GLPVEYLQVPSASMGRDIKVQFQ---GGGP---------HAVYLLDGLRA
MMAR_0328|M.marinum_M               GLPVEYLQIPSAAMGRDIKVQFQ---GGGA---------HSVYLLDGLRA
MUL_4793|M.ulcerans_Agy99           GLPVEYLQIPSAAMGRDIKVQFQ---GGGA---------HSVYLLDGLRA
Mflv_3335|M.gilvum_PYR-GCK          GLPVEYLDVFSPSMNRDIRIQFQ---GGGP---------HAVYLLDGLRA
Mvan_3061|M.vanbaalenii_PYR-1       GLPVEYLDVFSPSMGRDIRVQFQ---GGGP---------RAVYLLDGLRA
TH_2079|M.thermoresistible__bu      GLPVEYLDVYSASMGRNIRVQFQPATTPGSDGKEVIAGARAVYMLDGMRA
MSMEG_6399|M.smegmatis_MC2_155      GLPVEYLDVYSPSMGRNLRVQFQ---GPGETVDDMRP-SRAVYLLDGLRA
MAB_0175|M.abscessus_ATCC_1997      GLPVEYLDVYSNSMGRNIRVEFQ---GGGP---------KAVYLLDGLRA
                                    *******:: * :*.::::::**     *          ::**:***:**

MLBr_02655|M.leprae_Br4923          QEDYNGWDINTPAFEEYYHSGLSVIMPVGGQSSFYSNWYQPSQGNGQHYT
MAV_5183|M.avium_104                QDDYNGWDINTPAFEEFYQSGLSVIMPVGGQSSFYSNWYQPSSGNGQNYT
Mb0134c|M.bovis_AF2122/97           QDDYNGWDINTPAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYT
Rv0129c|M.tuberculosis_H37Rv        QDDYNGWDINTPAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYT
MMAR_0328|M.marinum_M               QDDYNGWDINTPAFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYT
MUL_4793|M.ulcerans_Agy99           QDDYNGWDINTPAFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYT
Mflv_3335|M.gilvum_PYR-GCK          QEDYNGWDINTPAFEWFYQSGLSTIMPVGGQSSFYSDWYQPSRGNGQNYT
Mvan_3061|M.vanbaalenii_PYR-1       QEDYNGWDINTPAFEWFYQSGLSTIMPVGGQSSFYTDWYQPSRGNGQNYT
TH_2079|M.thermoresistible__bu      RDDYNGWDIETPAFEWFYDSGIAVVMPVGGQSSFYTDWYSPSNFNKQTYT
MSMEG_6399|M.smegmatis_MC2_155      QDDYSGWDINTPAFEWFYNSGISVVMPVGGQSSFYSDWYSPSSFNNQTYT
MAB_0175|M.abscessus_ATCC_1997      QDDFNGWDINTAAFEWFYQSGISVVMPVGGQSSFYTDWYSPSALNKQPYT
                                    ::*:.****:*.*** :*.**::.:**********::**.**  * * **

MLBr_02655|M.leprae_Br4923          YKWETFLTQEMPSWLQANKNVLPTGNAAVGLSMSGSSALILASYYPQQFP
MAV_5183|M.avium_104                YKWETFLTQEMPLWMQSNKQVSPAGNAAVGLSMSGGSALILAAYYPQQFP
Mb0134c|M.bovis_AF2122/97           YKWETFLTREMPAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFP
Rv0129c|M.tuberculosis_H37Rv        YKWETFLTREMPAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFP
MMAR_0328|M.marinum_M               YKWETFLTREMPAWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFP
MUL_4793|M.ulcerans_Agy99           YKWETFLTREMPAWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFP
Mflv_3335|M.gilvum_PYR-GCK          YKWETFLTQELPAWLEANRGVSRTGNAVVGLSMAGSASLTYAIHHPQQFI
Mvan_3061|M.vanbaalenii_PYR-1       YKWETFLSQELPAWLEANRGVSRTGNAVVGLSMAGSAALTYAIYHPQQFI
TH_2079|M.thermoresistible__bu      YKWETFLTRELPAYLASEKQVSSTGNGVVGLSMSGSSALILAAYYPQQFR
MSMEG_6399|M.smegmatis_MC2_155      YKWETFLTRELPAWLAANRNVSTTGNGVVGLSMSGSAALILSAFHPGQFR
MAB_0175|M.abscessus_ATCC_1997      YKWETFLTQELPAYLATNKQISATGNGVVGLSMSGGAALILAAFHPAQFR
                                    *******::*:* :: ::: :  :**..*****:*.::*  : .:* ** 

MLBr_02655|M.leprae_Br4923          YAASLSGFLNPSEGWWPTMIGLAMNDSGGYNANSMWGPSTDPAWKRNDPM
MAV_5183|M.avium_104                YAASLSGFLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDPAWKRNDPM
Mb0134c|M.bovis_AF2122/97           YAASLSGFLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSSDPAWKRNDPM
Rv0129c|M.tuberculosis_H37Rv        YAASLSGFLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSSDPAWKRNDPM
MMAR_0328|M.marinum_M               YAASLSGFLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDPAWKRNDPM
MUL_4793|M.ulcerans_Agy99           YAASLSGFLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDPAWKRNDPM
Mflv_3335|M.gilvum_PYR-GCK          YAASLSGFLNPSEGWWPMLIGLAMNDAGGFNAESMWGPSSDPAWKRNDPM
Mvan_3061|M.vanbaalenii_PYR-1       YAASLSGFLNPSEGWWPMLIGLAMNDAGGFNAESMWGPSSDPAWKRNDPM
TH_2079|M.thermoresistible__bu      YAASLSGYLNPSSTFMKQAIRVAMLDAGGYNVDNMWGPPWNQAWKRNDPV
MSMEG_6399|M.smegmatis_MC2_155      YAASLSGFLNPSSLLMQQAIRVAMLDAGGYNVDNMWGPPWDGAWKRNDPI
MAB_0175|M.abscessus_ATCC_1997      FAGSLSGFLNPSTIFMTNAIRVAMLDAGSYSVDNMWGPPWDPAWRRNDPT
                                    :*.****:****       * :** *:*.:..:.****. : **:**** 

MLBr_02655|M.leprae_Br4923          VQIPRLVANNTRIWVYCGNGAPNELG----GDN-IPAKFLESLTLSTNEI
MAV_5183|M.avium_104                VQIPRLVANNTRIWVYCGNGTPSDLG----GDN-VPAKFLEGLTLRTNEQ
Mb0134c|M.bovis_AF2122/97           VQIPRLVANNTRIWVYCGNGTPSDLG----GDN-IPAKFLEGLTLRTNQT
Rv0129c|M.tuberculosis_H37Rv        VQIPRLVANNTRIWVYCGNGTPSDLG----GDN-IPAKFLEGLTLRTNQT
MMAR_0328|M.marinum_M               VQIPRLVANNTRIWVYCGNGTPSDLG----GDN-MPAKFLEGLTLRTNQT
MUL_4793|M.ulcerans_Agy99           VQIPRLVANNTRIWVYCGNGTPSDLG----GDN-MPAKFLEGLTLRTNQT
Mflv_3335|M.gilvum_PYR-GCK          VNINQLVANNTRIWIYCGTGTPSDLDSGTPGQNLMAAQFLEGFTLRTNVA
Mvan_3061|M.vanbaalenii_PYR-1       VNINQLVANNTRIWIYCGTGTPSDLDNGTPGNNLMAAQFLEGFTLRTNIA
TH_2079|M.thermoresistible__bu      EQVERLVNNGTRLWIYCAPGGETELDVNADPNQSFNANSLESMAINGNKK
MSMEG_6399|M.smegmatis_MC2_155      RQVDRIVANGTRLWIYCAPGGATPLDDGADPNLAMSANSLETLAIKSNKD
MAB_0175|M.abscessus_ATCC_1997      VQAQALVAAGTRLYIYCAPGGSTPIDDNTDAGVALSASSLESLAVAGNKA
                                     :   :*  .**:::**. *  . :.        . *. ** :::  *  

MLBr_02655|M.leprae_Br4923          FQNTYAASGGRNGVFNFPPNGTHSWPYWNQQLVAMKPDIQQILNGSNNNA
MAV_5183|M.avium_104                FQNNYAAAGGRNGVFNFPANGTHSWPYWNQQLMAMKPDMQQVLLSGNTTA
Mb0134c|M.bovis_AF2122/97           FRDTYAADGGRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNGATPPA
Rv0129c|M.tuberculosis_H37Rv        FRDTYAADGGRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNGATPPA
MMAR_0328|M.marinum_M               FRDTYLASGGRNGVFNFPTNGTHSWPYWNQQLVAMKGDILKVLNGPAVPA
MUL_4793|M.ulcerans_Agy99           FRDTYLASGGRNGVFNFPTNGTHSWPYWNQQLVAMKGDILKVLNGPAVPA
Mflv_3335|M.gilvum_PYR-GCK          FRDNYIAAGGNNGVFNFPTSGTHSWGYWGQQLQQMKPDIQRVLGAQATA-
Mvan_3061|M.vanbaalenii_PYR-1       FRDNYIAAGGTNGVFNFPTSGTHSWGYWGQQLQQMKPDIQRVLGAQATV-
TH_2079|M.thermoresistible__bu      FQEKYVAAGGRNATFNFPPAGNHSWPYWATQLQALKPDLLATLNG-----
MSMEG_6399|M.smegmatis_MC2_155      FQEAYVRAGGRNATFTFPPAGNHAWPYWGAQLSALKPDLIASLNG-----
MAB_0175|M.abscessus_ATCC_1997      FQQAYTAAGGRNANFVFPASGNHSWPYWGQQLQALKGDLIATLNG-----
                                    *:: *   ** *. * **. *.*:* **  **  :* *:   * .     

MLBr_02655|M.leprae_Br4923          ----------------------
MAV_5183|M.avium_104                APAQPAQPAQPAQPAQPAQPAT
Mb0134c|M.bovis_AF2122/97           APAAPAA---------------
Rv0129c|M.tuberculosis_H37Rv        APAAPAA---------------
MMAR_0328|M.marinum_M               APAAPEAPAAPVAPAA------
MUL_4793|M.ulcerans_Agy99           APAAPEAPAAPVAPAA------
Mflv_3335|M.gilvum_PYR-GCK          ----------------------
Mvan_3061|M.vanbaalenii_PYR-1       ----------------------
TH_2079|M.thermoresistible__bu      ----------------------
MSMEG_6399|M.smegmatis_MC2_155      ----------------------
MAB_0175|M.abscessus_ATCC_1997      ----------------------