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MTQTGNTSASPQLAKQASHARILIAVMLFITVVINYMDRANLSIAMPAIADEMDLTKAQQGLLLSAFGWT YAALQIPGGWLVDRVRPRVLYPVCLALWSLATLFMGVIGGFVALIALRLLVGVFEAPAYPINNRVATTWF PERERASVIGFYTSGQFIGLALLTPVLSWLQATMSWHWVFIVTGAIGIGWAALWYLKYREPRESNANEAE LELIESGGALVDVVEDQPQRVAVTRADVATVLGRRKLWGIYLGQFCLTSTLWFFLTWFPTYLVEYRGMDY IKTGFLASLPFIAALVGVLFSGVLSDFLLRRGVSLGAARKGPIIAGLLLTTAMLGANYTDSTAMVVLFLS IAFFGNGLASITWSLVSALAPKRLLGLTGGMFNFIGNLSSIATPIIIGLLVTDESFAPGFVYMTVVTLIG IASYVLLVGRVERVREKAVTQPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6178 | - | - | 100% (443) | D-galactonate transporter |
| M. smegmatis MC2 155 | MSMEG_2549 | - | 4e-53 | 29.75% (437) | major facilitator superfamily protein |
| M. smegmatis MC2 155 | MSMEG_1320 | - | 9e-48 | 29.14% (429) | major facilitator superfamily protein MFS_1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1699c | - | 6e-13 | 25.67% (448) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_4046 | - | 2e-12 | 22.16% (379) | EmrB/QacA family drug resistance transporter |
| M. tuberculosis H37Rv | Rv1672c | - | 6e-13 | 25.67% (448) | integral membrane transport protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1396 | - | 4e-10 | 30.18% (169) | EmrB/QacA family drug resistance transporter |
| M. marinum M | MMAR_0596 | - | 2e-24 | 24.62% (394) | integral membrane transport protein |
| M. avium 104 | MAV_3846 | - | 1e-11 | 21.71% (433) | sugar transporter family protein |
| M. thermoresistible (build 8) | TH_2039 | - | 5e-12 | 22.86% (420) | PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_3155 | - | 7e-15 | 23.97% (363) | hypothetical protein MUL_3155 |
| M. vanbaalenii PYR-1 | Mvan_4127 | - | 4e-13 | 22.03% (413) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1699c|M.bovis_AF2122/97 ---------------------------------------------MATIA
Rv1672c|M.tuberculosis_H37Rv ---------------------------------------------MATIA
MMAR_0596|M.marinum_M ---------------------------------------------MAVLD
MAV_3846|M.avium_104 ------------------MAGRRPQAPMTGNGTRPTPKYPGGMQAWGMQT
TH_2039|M.thermoresistible__bu --------------------------------------------------
MSMEG_6178|M.smegmatis_MC2_155 --------------------------------------------MTQTGN
Mvan_4127|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1396|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_4046|M.gilvum_PYR-GCK MTALNDAERAAIQRDAEGRGKRGSDRASGRALPARVTGSGESAGGRGGDA
MUL_3155|M.ulcerans_Agy99 --------------------------------------------MTTNGR
Mb1699c|M.bovis_AF2122/97 A---SPTHNALGKAARRLLPLLFVLYVINFVDRANISVAALAMNADLRLS
Rv1672c|M.tuberculosis_H37Rv A---SPTHNALGKAARRLLPLLFVLYVINFVDRANISVAALAMNADLRLS
MMAR_0596|M.marinum_M TGERSLEARTIRKLGIRIVPFLMALYFVNYLDRTNLGIARADISAHLQLT
MAV_3846|M.avium_104 DPVATPDVGAGTRWSIMVVSLLATASSFLFIN--GVAFLIPSLQGARGIR
TH_2039|M.thermoresistible__bu MPVSS--ISPARRWSMLVIALAATLFSVVFIN--GVAFVIPTLHREHGLS
MSMEG_6178|M.smegmatis_MC2_155 TSASPQLAKQASHARILIAVMLFITVVINYMDRANLSIAMPAIADEMDLT
Mvan_4127|M.vanbaalenii_PYR-1 ------------MRPWIVWATGLLAYIVAVLDRTTLGVSGLAAADRFGAG
MAB_1396|M.abscessus_ATCC_1997 -------MRPEYPRPWITLWVVLFGLFMILLDSTIVSVANPAIKAGFGAD
Mflv_4046|M.gilvum_PYR-GCK GRRGRTPAWMPSRRFFAAVIAIGGMQLLATMDSTIAIVALPKIQDELGLS
MUL_3155|M.ulcerans_Agy99 AIRGGLADAVGGPARMRVIVLLALVVGLEGASNGTIGALAVVLKQAFGIT
. .
Mb1699c|M.bovis_AF2122/97 ATAYGTAAGVFFLGYVLFQVPANAALARFGAGRTLTAVVLAWGVCSAATA
Rv1672c|M.tuberculosis_H37Rv ATAYGTAAGVFFLGYVLFQVPANAALARFGAGRTLTAVVLAWGVCSAATA
MMAR_0596|M.marinum_M ATMFGLASGIFFIGYVLVEVPSNLALDRYGARRWLARIAVSWGIVVVATG
MAV_3846|M.avium_104 LDEAGLLASMPSWGMVVTLVAWGYVLDRVGERVVMTTGSALTALAAYAAS
TH_2039|M.thermoresistible__bu LAQAGLLSALPSFGMVATLIAWGYLVDRIGERIVLTVGSALTAASAFAAA
MSMEG_6178|M.smegmatis_MC2_155 KAQQGLLLSAFGWTYAALQIPGGWLVDRVRPRVLYPVCLALWSLATLFMG
Mvan_4127|M.vanbaalenii_PYR-1 PSLLSTFVVLQVVVYAGAQVPAGLLLDRYGSRALIASGAALMASGQLGLA
MAB_1396|M.abscessus_ATCC_1997 YSSTVWVTSAYLLGYAVPLLITGRLGDQFGPRSMYLSGLAVFTAASLWCG
Mflv_4046|M.gilvum_PYR-GCK DAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTIASVLCG
MUL_3155|M.ulcerans_Agy99 NLQVGLLVTASTAIGIVVMLVSGTLADRVNRTRVLWITVLIWSVAMALGG
: . .
Mb1699c|M.bovis_AF2122/97 LVTSAHTLYLARFALGVAEGGFFPGVIAYLTVWFPC-AQRARAVATFLLA
Rv1672c|M.tuberculosis_H37Rv LVTSAHTLYLARFALGVAEGGFFPGVIAYLTVWFPC-AQRARAVATFLLA
MMAR_0596|M.marinum_M FAPNATTLLVLRFLLGVAEAGLFPGVIYYLSRWFPR-DYRARVVALFMMA
MAV_3846|M.avium_104 SAHSMVLIAVYLFLGGMAAASCNTAGGRLVSAWFPP-HQRGLAMGIRQTA
TH_2039|M.thermoresistible__bu AVDSLLLVGVFLLLGGMAAASSNTASARVVVGWFPP-HQRGLVMGIRQTA
MSMEG_6178|M.smegmatis_MC2_155 VIGGFVALIALRLLVGVFEAPAYPINNRVATTWFPE-RERASVIGFYTSG
Mvan_4127|M.vanbaalenii_PYR-1 FTESLPAAIAARAVVGLGDAVTFISVLRLVPHWFAP-RQIPVVTQLTGIC
MAB_1396|M.abscessus_ATCC_1997 LAGSIGWLIAARVVQGIGAAMLTPQTLTVVQRVFPP-ERRGTAMGVWGAV
Mflv_4046|M.gilvum_PYR-GCK IAWDEATLVIARLLQGVGAAIASPTALALIATTFPKGPARNAATAVFAAM
MUL_3155|M.ulcerans_Agy99 ISAGYGWLLASRVALGAVVAVGGPVVASLMGDFFAQ-HERGRIYGFVLAG
. * . *.
Mb1699c|M.bovis_AF2122/97 IPVANTVGLPLSGLIVGHVH-MAGLPGWRAMFVIEALPALLLAPLLRRLL
Rv1672c|M.tuberculosis_H37Rv IPVANTVGLPLSGLIVGHVH-MAGLPGWRAMFVIEALPALLLAPLLRRLL
MMAR_0596|M.marinum_M SPIAAALGTPLAAWLIHLGNGVFGLAGWQFMMIAVGVPAIVLGFACWYYL
MAV_3846|M.avium_104 QPLGIALGAMVIPELAE-HGPQAGLR-FTALACVFGAVASVIG-------
TH_2039|M.thermoresistible__bu QPLGVALGALVIPRLAQSHGISAALL-FPAAVCAVAAVICLIG-------
MSMEG_6178|M.smegmatis_MC2_155 QFIGLALLTPVLSWLQATMSWHWVFIVTGAIGIGWAALWYLKYREPR---
Mvan_4127|M.vanbaalenii_PYR-1 GQLGQVLSAIPFLALLSASGWSVAYASAAALGVLSIVLTLAIVR------
MAB_1396|M.abscessus_ATCC_1997 AGIATLVGPVAGGLLVDGWGWQWIFYVNVPVGVLGIILGAIYIPRMPTHR
Mflv_4046|M.gilvum_PYR-GCK TGVGSVMGLVVG-GALTEVSWRLAFLVNVPIGLIMIYLARKTLRETNRER
MUL_3155|M.ulcerans_Agy99 EGICTALGVLVSGWLAAITWRLSFLWLAVTGLLLTLALARTVP-------
: :
Mb1699c|M.bovis_AF2122/97 PDNPQRASWLTPEERAELSARLTEDTPAPTG-------------------
Rv1672c|M.tuberculosis_H37Rv PDNPQRASWLTPEERAELSARLTEDTPAPTG-------------------
MMAR_0596|M.marinum_M VDRPGDAAWLEPDERQWLVDTLAEEQRQVAGD-------------FHFPL
MAV_3846|M.avium_104 --------IVDPPRKPRASASDQELASPYRG-------------------
TH_2039|M.thermoresistible__bu --------VLDPPRPPRASADGRHPQNPYRG-------------------
MSMEG_6178|M.smegmatis_MC2_155 -ESNANEAELELIESGGALVDVVEDQPQRVAV-------------TR---
Mvan_4127|M.vanbaalenii_PYR-1 ----------NTPDGSAATSETMSVRETLTS-------------------
MAB_1396|M.abscessus_ATCC_1997 HRLDLLGMALSAVGMFAFVFALQEGESFQWAPGVWAMMAAGLVVLGVFVW
Mflv_4046|M.gilvum_PYR-GCK LKLDAAGALLATMGCTAAVFGFSMGPEAGWMSPVTIGSGIAAVGCLIAFL
MUL_3155|M.ulcerans_Agy99 ----------EPARGGDTFGASAGSDRRDCSN------------------
Mb1699c|M.bovis_AF2122/97 RSSGAGWDLVLFAVVYGGLYFALYALQFFLPQLVA----SLAHGTATLTA
Rv1672c|M.tuberculosis_H37Rv RSSGAGWDLVLFAVVYGGLYFALYALQFFLPQLVA----SLAHGTATLTA
MMAR_0596|M.marinum_M RRALTSPRIWALALVYFGIAYGLYALTFFLPSIISGFKKSFGIDFSIVQV
MAV_3846|M.avium_104 --SLTLWRIHAVAGLM--MMPQTVTVTFMLVWLIR------NLHWSVAAA
TH_2039|M.thermoresistible__bu --SGLLWRIHAVSVLL--VVPQGVIWTFTLVWLMT------ERSWSAGSA
MSMEG_6178|M.smegmatis_MC2_155 ADVATVLGRRKLWGIYLGQFCLTSTLWFFLTWFPT--YLVEYRGMDYIKT
Mvan_4127|M.vanbaalenii_PYR-1 -VKTVWLRPGTRLGFFTHMGTQFSITVFALMWGLP--YLTEAQGLSAGVA
MAB_1396|M.abscessus_ATCC_1997 WQSANRGEPLIPLRLFADRNFSLAGVGIASMSFCVISTGLPMMFYTQLAL
Mflv_4046|M.gilvum_PYR-GCK WVERTAENPVVPFELFLDRNRVATFAAVFLAGGVMFTLTVTIGLYVQDIM
MUL_3155|M.ulcerans_Agy99 -DTLAAAVIAQRVSAHPHLILQESPEGRSLRWAVG--------YVLKIRT
Mb1699c|M.bovis_AF2122/97 ATLAALPYGVAALAMLAWSHRSIDRS--GAQAGH-ITLPTTAAGSAALGA
Rv1672c|M.tuberculosis_H37Rv ATLAALPYGVAALAMLAWSHRSIDRS--GAQAGH-ITLPTTAAGSAALGA
MMAR_0596|M.marinum_M GLIAAIPYTCAAVAMYLWS-RHADAT--GEQVWH-VAVPMLLGG-LAIPV
MAV_3846|M.avium_104 GALVTLSQLLGALGRVAVG-RWSDRL--GSRMRP-VRYIAAAAVLVLLLL
TH_2039|M.thermoresistible__bu GTMVMIAQVLGAGGRVAAG-RWSDLV--GSRLRP-IRTIALAAAAAMALL
MSMEG_6178|M.smegmatis_MC2_155 GFLASLPFIAALVGVLFSGVLSDFLLRRGVSLGA-ARKGPIIAGLLLTTA
Mvan_4127|M.vanbaalenii_PYR-1 GALLSLSVVSAIGCGVLIGILTGRYP---HRRSR-MVLAIITSNAVVWTV
MAB_1396|M.abscessus_ATCC_1997 GFSPTKAALTQAPTAIVSGILAPLAGWLVDRVRPSILIGGGIALMIASTL
Mflv_4046|M.gilvum_PYR-GCK GYSALRAGVGFIPFVIALGIGLGVSSALVSKYPPRVLVIGGGVLVLAAMI
MUL_3155|M.ulcerans_Agy99 NVALMVASSFGYFFYTGLGTFAVALLRSRFRISQTLAISLIAIIGVGAPI
. .
Mb1699c|M.bovis_AF2122/97 ALSP-MSPIVTLSWLTIAVAGILAAMPAFWSRCTAALAG---PRVAV-AI
Rv1672c|M.tuberculosis_H37Rv ALSP-MSPIVTLSWLTIAVAGILAAMPAFWSRCTAALAG---PRVAV-AI
MMAR_0596|M.marinum_M ALHL-HTPVLVMVAVAITAMGVFAAIPSFWALPSNFLTG---TAAAG-AI
MAV_3846|M.avium_104 AWAD-YLNSRWQAGLMVAISVIAVLDNGLEATAITEFAG---PYWSGRAL
TH_2039|M.thermoresistible__bu ALTD-ALDSPVSVAFMVIAAVVTVSDNSLAFTAIAEIAG---PYWTGRAL
MSMEG_6178|M.smegmatis_MC2_155 MLGANYTDSTAMVVLFLSIAFFGNGLASITWSLVSALAP---KRLLGLTG
Mvan_4127|M.vanbaalenii_PYR-1 VLALPGPAPLWLLIVLIVVISVGGPGSMVGFDFARTFNP---RATLGTAQ
MAB_1396|M.abscessus_ATCC_1997 WWTLLMRPETQMWQLMLPAAGIGAAMACIWGPLATTATRNLPPSVAGAGS
Mflv_4046|M.gilvum_PYR-GCK YGSTLDANIPYFPNLVLPITIGGLGIGMIVVPLMISAIAGVGFDQIGPVS
MUL_3155|M.ulcerans_Agy99 GTLCAGRLADWLIGRGYLGARLGVAGAAFLVAGGFFVPALLTDNVVIAVV
.
Mb1699c|M.bovis_AF2122/97 ATVNAVASLASFAGPYATGHLKDATGTYHLALLTVAAVL---AAAAACSL
Rv1672c|M.tuberculosis_H37Rv ATVNAVASLASFAGPYATGHLKDATGTYHLALLTVAAVL---AAAAACSL
MMAR_0596|M.marinum_M GLINSVGNLGGFAAPYLTGALEQVTGTDKAGMWAVGAMM---LMSAFVVV
MAV_3846|M.avium_104 GIQNTTQRMMAAAGPPLFGALISAAK--YPPAWLLCALF---PLAAMPLV
TH_2039|M.thermoresistible__bu GTQNTSQLLTTAITPPLFGGLIGVAG--YPVAFALCAVL---PLAAVPLV
MSMEG_6178|M.smegmatis_MC2_155 GMFNFIGNLSSIATPIIIGLLVTDESFAPGFVYMTVVTL---IGIASYVL
Mvan_4127|M.vanbaalenii_PYR-1 GMVNMGGFIASLLLMQAMGMVMQAMGGISFESFRSAWMV---QYVVWALA
MAB_1396|M.abscessus_ATCC_1997 GVYNTLRQVGGVVGSSAMGALMTARLTATMPAMPPGSGS---TPEAALPP
Mflv_4046|M.gilvum_PYR-GCK AIALMLQNLGGPVVLAIIQAVITSRTLYLGGTTGPVKDM---NAAQMHAL
MUL_3155|M.ulcerans_Agy99 AAFLAAIGLGGVNPPLDAARLDIMHSRLWGRAEAIRTTLRSGFTAAAPLV
. : :
Mb1699c|M.bovis_AF2122/97 LLRHAGRTVCANDSEIMLHPSPATPFV-----------------------
Rv1672c|M.tuberculosis_H37Rv LLRHAGRTVCANDSEIMLHPSPATPFV-----------------------
MMAR_0596|M.marinum_M LLRAVPGSPTAAE-----RPN-----------------------------
MAV_3846|M.avium_104 PTRLLPPGLETRARRQSVRRLRWWRAVRSHALPDIVRRPGQPG-------
TH_2039|M.thermoresistible__bu PADPATPQIRPSSP-ESPRRVR----------------------------
MSMEG_6178|M.smegmatis_MC2_155 LVGRVERVREKAVTQPA---------------------------------
Mvan_4127|M.vanbaalenii_PYR-1 VVGILITRRKARRLLRDGNDRILLEGVNP---------------------
MAB_1396|M.abscessus_ATCC_1997 GLRAPFSAAMAQSMLLGIAALALGLVAALFMRPGGSQVGAVPLDDVVSVE
Mflv_4046|M.gilvum_PYR-GCK DQGYSYGLLWVAAVAVIVGAVALFIGYTAQQVAHAQEVKDAIDAGEL---
MUL_3155|M.ulcerans_Agy99 FAWYPCSWRRSGARPVGWQPHRPG--------------------------
Mb1699c|M.bovis_AF2122/97 -
Rv1672c|M.tuberculosis_H37Rv -
MMAR_0596|M.marinum_M -
MAV_3846|M.avium_104 -
TH_2039|M.thermoresistible__bu -
MSMEG_6178|M.smegmatis_MC2_155 -
Mvan_4127|M.vanbaalenii_PYR-1 -
MAB_1396|M.abscessus_ATCC_1997 D
Mflv_4046|M.gilvum_PYR-GCK -
MUL_3155|M.ulcerans_Agy99 -