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M. smegmatis MC2 155 MSMEG_6044 (-)

annotation: ligand-binding /sugar binding domain-containing protein
coordinates: 6111320 - 6112420
length: 366

PRSPHPPRRATLASLAAELKVSRTTISNAYNRPDQLSADLRERIFDAAKRLGYPGPDPVARSLRTRKAGA
VGLMITEPLDYSFSDPAALDFVAGLAESCEEAGQGLLLVAVGPNRTFEEGSNSVLAAGVDGFVVYSASDD
DPYLPVLQQRQLPMVVVDQPKDVPGVSRISIDDRGAMRELAEYVLELGHRDIGLLTMRLGRDWPHGDPRP
ALADPERVLSPHFHVQRERIHGVYDAMSAAGLDPSSLTVVESYEHLPTSGGAAAEVALEVNPRITALMCT
ADVLALSAMDHLRSRGIYVPGHMTVTGFDGVRDALRRGLTTVKQPSMEKGRRAGHLLHNPPGSGLPVIDV
LETEVVRGRTSGPPA*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. smegmatis MC2 155 MSMEG_6044 - - 100% (366) ligand-binding /sugar binding domain-containing protein
M. smegmatis MC2 155 MSMEG_6376 - 4e-21 26.87% (361) transcriptional regulator LacI family protein
M. smegmatis MC2 155 MSMEG_2954 - 7e-19 28.26% (368) LacI-family protein transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3606c - 1e-152 74.93% (363) transcriptional regulatory protein LacI-family
M. gilvum PYR-GCK Mflv_1457 - 1e-176 82.24% (366) periplasmic binding protein/LacI transcriptional regulator
M. tuberculosis H37Rv Rv3575c - 1e-152 74.93% (363) transcriptional regulatory protein LacI-family
M. leprae Br4923 - - - - -
M. abscessus ATCC 19977 MAB_2023c - 2e-07 26.69% (326) LacI family transcriptional regulator
M. marinum M MMAR_5070 - 1e-153 74.66% (363) PurR family transcriptional regulator
M. avium 104 MAV_0585 - 1e-152 74.10% (363) transcriptional regulator, LacI family protein
M. thermoresistible (build 8) - - - - -
M. ulcerans Agy99 MUL_4146 - 1e-153 74.38% (363) PurR family transcriptional regulator
M. vanbaalenii PYR-1 Mvan_5317 - 1e-173 81.97% (366) periplasmic binding protein/LacI transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1457|M.gilvum_PYR-GCK          MSRSPTPRRRATLASLAAELKVSRTTVSNAYNRPDQLSAELRERVLSTAK
Mvan_5317|M.vanbaalenii_PYR-1       MPRSPTPRRRATLASLAAELKVSRTTVSNAYNRPDQLSAELRERVLSTAE
MSMEG_6044|M.smegmatis_MC2_155      MPRSPHPPRRATLASLAAELKVSRTTISNAYNRPDQLSADLRERIFDAAK
Mb3606c|M.bovis_AF2122/97           --MSPTPRRRATLASLAAELKVSRTTVSNAFNRPDQLSADLRERVLATAK
Rv3575c|M.tuberculosis_H37Rv        --MSPTPRRRATLASLAAELKVSRTTVSNAFNRPDQLSADLRERVLATAK
MMAR_5070|M.marinum_M               --MSPTPRRRATLASLAAELKVSRSTISNAFNRPDQLSAELRERVLATAK
MUL_4146|M.ulcerans_Agy99           --MSPTPRRRATLASLAAELKVSRSTISNAFNRPDQLSVELRERVLATAK
MAV_0585|M.avium_104                --MSPTPRRRATLASLADELKVSRTTVSNAFNRPDQLSADLRERVLATAK
MAB_2023c|M.abscessus_ATCC_199      -------------------MGLSKTTVADALGGSGRVSEATREKTRLVAE
                                                       : :*::*:::* . ..::*   **:   .*:

Mflv_1457|M.gilvum_PYR-GCK          RLGYPGPDPVARSLRTRRAGAVGLVITEPLNYSFSDPAALDFVAGLAESC
Mvan_5317|M.vanbaalenii_PYR-1       RLGYPGPDPVARSLRTRRAGAVGLVITEPLNYSFSDPAALDFVAGLAESC
MSMEG_6044|M.smegmatis_MC2_155      RLGYPGPDPVARSLRTRKAGAVGLMITEPLDYSFSDPAALDFVAGLAESC
Mb3606c|M.bovis_AF2122/97           RLGYAGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARDFVAGVAQSC
Rv3575c|M.tuberculosis_H37Rv        RLGYAGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARDFVAGVAQSC
MMAR_5070|M.marinum_M               RMGYPGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARDFVTGVAQSC
MUL_4146|M.ulcerans_Agy99           RMGYPGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARDFVTGVAQSC
MAV_0585|M.avium_104                RLGYPGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARDFVTGVAQSC
MAB_2023c|M.abscessus_ATCC_199      RMGYVS-NRAARLLRRNETGALGLYIPGDVRNLS---FYMELAFGAADES
                                    *:** . : .** ** ..:**:** :.  :          ::. * *:..

Mflv_1457|M.gilvum_PYR-GCK          EAVGQGLLLVAVGPNRSVAEGSAAVLAAGVDGFVVYSASDDDPYLPAVME
Mvan_5317|M.vanbaalenii_PYR-1       EAVGQGLLLVAVGPNRSVADGSAAVLAAGVDGFVVYSASDDDPYLPAVLQ
MSMEG_6044|M.smegmatis_MC2_155      EEAGQGLLLVAVGPNRTFEEGSNSVLAAGVDGFVVYSASDDDPYLPVLQQ
Mb3606c|M.bovis_AF2122/97           EELGQGLQLVSVGSSRSLADGTAAVLGAGVDGFVVYSVGDDDPYLQVVLQ
Rv3575c|M.tuberculosis_H37Rv        EELGQGLQLVSVGSSRSLADGTAAVLGAGVDGFVVYSVGDDDPYLQVVLQ
MMAR_5070|M.marinum_M               EELGQGLLLVAVGASRSLEDGTAAVLNAGVDGFVVYSVRDDDPYLQVVLQ
MUL_4146|M.ulcerans_Agy99           EELGQGLLLVAVGASRSLEDGTAAVLNAGVDGFVVYSVRDDDPYLQVVLQ
MAV_0585|M.avium_104                EALGQGLLLVAVGPSRSLDEGTAAVLSAGVDGFVVYSVCDDDPYLQAVLQ
MAB_2023c|M.abscessus_ATCC_199      AALGLDLTLIGR-----HLTGENRSRPPQVDGIIAVDPVPGDAALESLLT
                                       * .* *:.         *      . ***::. .   .*. *  :  

Mflv_1457|M.gilvum_PYR-GCK          RHLPVVVVDQPRDVPG---ASQVRIDDRAAMRSLAEHVIDLGHREIGLLT
Mvan_5317|M.vanbaalenii_PYR-1       RHLPVVVVDQPRDVAG---TSRVCIDDRAAMRRLAEHVIELGHREIGLLT
MSMEG_6044|M.smegmatis_MC2_155      RQLPMVVVDQPKDVPG---VSRISIDDRGAMRELAEYVLELGHRDIGLLT
Mb3606c|M.bovis_AF2122/97           RRLPVVVVDQPKDLSG---VSRVGIDDRAAMRELAGYVLGLGHRELGLLT
Rv3575c|M.tuberculosis_H37Rv        RRLPVVVVDQPKDLSG---VSRVGIDDRAAMRELAGYVLGLGHRELGLLT
MMAR_5070|M.marinum_M               RRLPVVVVDQPKELAG---VSRVGIDDRAAMRKIADYVLGLGHRQIGLLT
MUL_4146|M.ulcerans_Agy99           RRLPVVVVDQPKELAG---VSRVGIDDRAAMRKIADYVLSLGHRQIGLLT
MAV_0585|M.avium_104                RRLPVVVVDQPKGLTG---VSRVGIDDRAAMRELADYVLGLGHREIGLLT
MAB_2023c|M.abscessus_ATCC_199      SNVPIVTVGRILDKDVSHHAAEIEIDHYRMVTLLLDAIRAAGGKRPALAA
                                     .:*:*.*.:         .:.: **.   :  :   :   * :  .* :

Mflv_1457|M.gilvum_PYR-GCK          MRLGRDWPHG-PGPALADPERVRAPNFHVQCERIHGVYDAMTAAGLDPAS
Mvan_5317|M.vanbaalenii_PYR-1       MRLGRDRPHGGSTPVLADPERLRTPHFHVQGERIRGVYDAMTAAGLDPGS
MSMEG_6044|M.smegmatis_MC2_155      MRLGRDWPHGDPRPALADPERVLSPHFHVQRERIHGVYDAMSAAGLDPSS
Mb3606c|M.bovis_AF2122/97           MRLGRDRRQD-----LVDAERLRSPTFDVQRERIVGVWEAMTAAGVDPDS
Rv3575c|M.tuberculosis_H37Rv        MRLGRDRRQD-----LVDAERLRSPTFDVQRERIVGVWEAMTAAGVDPDS
MMAR_5070|M.marinum_M               MRLGRDRRQD-----LVDAERLKSPTFDVQRERITGVWEAMTAAGVDPES
MUL_4146|M.ulcerans_Agy99           MRLGRDRRQD-----LVDAERLKSPTFDVQRERITGVWEAMTAAGVDPES
MAV_0585|M.avium_104                MRLGRDRRQG-----LVDAERLRSPAFDVQRERITGVWEAMTAAGVDPDS
MAB_2023c|M.abscessus_ATCC_199      LDQGAD----------------SSYVFDVSR----GYQEWCAKAGVVPLA
                                    :  * *                 :  *.*.     *  :  : **: * :

Mflv_1457|M.gilvum_PYR-GCK          LTLVESYEHLPTSGGAGADIALEANPRITALMCTADVLALSAMDHLRAKG
Mvan_5317|M.vanbaalenii_PYR-1       LTVVESYEHLPSSGGAGADVALDANPRITALMCTADVLALSAMDHLRAKG
MSMEG_6044|M.smegmatis_MC2_155      LTVVESYEHLPTSGGAAAEVALEVNPRITALMCTADVLALSAMDHLRSRG
Mb3606c|M.bovis_AF2122/97           LTVVESYEHLPTSGGTAAKVALQANPRLTALMCTADILALSAMDYLRAHG
Rv3575c|M.tuberculosis_H37Rv        LTVVESYEHLPTSGGTAAKVALQANPRLTALMCTADILALSAMDYLRAHG
MMAR_5070|M.marinum_M               LTVVESYEHLPTSGGDAAKVALEANPRITALMCTADILALSAMDYLRGHG
MUL_4146|M.ulcerans_Agy99           LTVVESYEHLPTSGGDAAKVALEANPRITALMCTADILALSAMDYLRGHG
MAV_0585|M.avium_104                LTVVESYEHLPESGGAAAKVALEANPRITALMCTADILALSAMDYLRAHG
MAB_2023c|M.abscessus_ATCC_199      TRLSATPTDVELAQAIRGIVEHQG---IDALVVGAQGLAARSLPVLQSLG
                                      :  :  .:  : .  . :  :    : **:  *: **  ::  *:. *

Mflv_1457|M.gilvum_PYR-GCK          IYVPGQMTVTGFDG--VPEARQRGLTTVAQPGVEKGRRAGELLH--NPPR
Mvan_5317|M.vanbaalenii_PYR-1       IYVPGQMTVTGFDG--VPEARRRGLTTVVQPSVEKGRRAGELLH--HPPR
MSMEG_6044|M.smegmatis_MC2_155      IYVPGHMTVTGFDG--VRDALRRGLTTVKQPSMEKGRRAGHLLH--NPPG
Mb3606c|M.bovis_AF2122/97           IYVPGQMTVTGFDG--VPEALSRGLTTVAQPSLHKGHRAGELLL--KPPR
Rv3575c|M.tuberculosis_H37Rv        IYVPGQMTVTGFDG--VPEALSRGLTTVAQPSLHKGHRAGELLL--KPPR
MMAR_5070|M.marinum_M               IYVPGQMTVTGFDG--VPEAISRGLTTVSQPSLQKGRRAGELLQ--NPPR
MUL_4146|M.ulcerans_Agy99           IYVPGQMTVTGFDG--VPEAISRGLTTVSQPSLQKGRRAGELLQ--NPPR
MAV_0585|M.avium_104                VYVPGQLTVTGFDG--VPDAISRGLTTVSQSSLHKGRRAGELLL--KPAR
MAB_2023c|M.abscessus_ATCC_199      HEVGSNFHLGTLVGDPATELTNPDIHAVDLRPREFGHQAVTFLHDIIAGR
                                      * .:: :  : *  . :    .: :*     . *::*  :*    .  

Mflv_1457|M.gilvum_PYR-GCK          SGLPVVEVLDTEVIRGRTSGPPA-------
Mvan_5317|M.vanbaalenii_PYR-1       SGLPVIEVLDTEMVRGRTSGPPA-------
MSMEG_6044|M.smegmatis_MC2_155      SGLPVIDVLETEVVRGRTSGPPA-------
Mb3606c|M.bovis_AF2122/97           SGLPVIEVLDTELVRGRTAGPPA-------
Rv3575c|M.tuberculosis_H37Rv        SGLPVIEVLDTELVRGRTAGPPA-------
MMAR_5070|M.marinum_M               SGLPVVELLDTELIRGRTAGPPA-------
MUL_4146|M.ulcerans_Agy99           SGLPVVELLDTELIRGRTAGPPA-------
MAV_0585|M.avium_104                SGLPVVELLDTELIRGRTAGPPA-------
MAB_2023c|M.abscessus_ATCC_199      ASANDRRTHQARLKIAGVSSPPAIRRAMSD
                                    :.       ::.:  . .:.***

species	id	gene	e-value	identity (len)	annotation
M. smegmatis MC2 155	MSMEG_6044	-	-	100% (366)	ligand-binding /sugar binding domain-containing protein
M. smegmatis MC2 155	MSMEG_6376	-	4e-21	26.87% (361)	transcriptional regulator LacI family protein
M. smegmatis MC2 155	MSMEG_2954	-	7e-19	28.26% (368)	LacI-family protein transcriptional regulator