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GLSKTTVADALGGSGRVSEATREKTRLVAERMGYVSNRAARLLRRNETGALGLYIPGDVRNLSFYMELAF GAADESAALGLDLTLIGRHLTGENRSRPPQVDGIIAVDPVPGDAALESLLTSNVPIVTVGRILDKDVSHH AAEIEIDHYRMVTLLLDAIRAAGGKRPALAALDQGADSSYVFDVSRGYQEWCAKAGVVPLATRLSATPTD VELAQAIRGIVEHQGIDALVVGAQGLAARSLPVLQSLGHEVGSNFHLGTLVGDPATELTNPDIHAVDLRP REFGHQAVTFLHDIIAGRASANDRRTHQARLKIAGVSSPPAIRRAMSD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2023c | - | - | 100% (329) | LacI family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3606c | - | 3e-07 | 24.28% (313) | transcriptional regulatory protein LacI-family |
| M. gilvum PYR-GCK | Mflv_1457 | - | 2e-08 | 27.51% (189) | periplasmic binding protein/LacI transcriptional regulator |
| M. tuberculosis H37Rv | Rv3575c | - | 4e-07 | 24.28% (313) | transcriptional regulatory protein LacI-family |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_5070 | - | 2e-06 | 25.00% (228) | PurR family transcriptional regulator |
| M. avium 104 | MAV_0585 | - | 2e-07 | 26.32% (228) | transcriptional regulator, LacI family protein |
| M. smegmatis MC2 155 | MSMEG_6736 | - | 6e-28 | 32.46% (305) | LacI-family protein transcriptional regulator |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_4146 | - | 1e-06 | 25.00% (228) | PurR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5317 | - | 1e-09 | 27.92% (197) | periplasmic binding protein/LacI transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_5070|M.marinum_M --MSPTPRRRATLASLAAELKVSRSTISNAFNRPDQLSAELRERVLATAK
MUL_4146|M.ulcerans_Agy99 --MSPTPRRRATLASLAAELKVSRSTISNAFNRPDQLSVELRERVLATAK
MAV_0585|M.avium_104 --MSPTPRRRATLASLADELKVSRTTVSNAFNRPDQLSADLRERVLATAK
Mb3606c|M.bovis_AF2122/97 --MSPTPRRRATLASLAAELKVSRTTVSNAFNRPDQLSADLRERVLATAK
Rv3575c|M.tuberculosis_H37Rv --MSPTPRRRATLASLAAELKVSRTTVSNAFNRPDQLSADLRERVLATAK
Mflv_1457|M.gilvum_PYR-GCK MSRSPTPRRRATLASLAAELKVSRTTVSNAYNRPDQLSAELRERVLSTAK
Mvan_5317|M.vanbaalenii_PYR-1 MPRSPTPRRRATLASLAAELKVSRTTVSNAYNRPDQLSAELRERVLSTAE
MSMEG_6736|M.smegmatis_MC2_155 -MAGERGRGRVTLRDVALAANVSTTTVSDSLNGSGSLPEKTRQRVRKIAL
MAB_2023c|M.abscessus_ATCC_199 -------------------MGLSKTTVADALGGSGRVSEATREKTRLVAE
:* :*:::: . .. :. *::. *
MMAR_5070|M.marinum_M RMGYPGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARDFVTGVAQSC
MUL_4146|M.ulcerans_Agy99 RMGYPGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARDFVTGVAQSC
MAV_0585|M.avium_104 RLGYPGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARDFVTGVAQSC
Mb3606c|M.bovis_AF2122/97 RLGYAGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARDFVAGVAQSC
Rv3575c|M.tuberculosis_H37Rv RLGYAGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARDFVAGVAQSC
Mflv_1457|M.gilvum_PYR-GCK RLGYPGPDPVARSLRTRRAGAVGLVITEPLNYSFSDPAALDFVAGLAESC
Mvan_5317|M.vanbaalenii_PYR-1 RLGYPGPDPVARSLRTRRAGAVGLVITEPLNYSFSDPAALDFVAGLAESC
MSMEG_6736|M.smegmatis_MC2_155 ELGYR-PSVAARSLRNGRTGILVIAMLPSDVDAESLWHVDYFMRVMAGAA
MAB_2023c|M.abscessus_ATCC_199 RMGYV-SNRAARLLRRNETGALGLYIPG---DVRNLSFYMELAFGAADES
.:** .. .** ** .:* : : : . : * .
MMAR_5070|M.marinum_M EELGQGLLLVAVGASRSLEDGTAAVLNAGVDGFVVYSVRDDDPYLQVVLQ
MUL_4146|M.ulcerans_Agy99 EELGQGLLLVAVGASRSLEDGTAAVLNAGVDGFVVYSVRDDDPYLQVVLQ
MAV_0585|M.avium_104 EALGQGLLLVAVGPSRSLDEGTAAVLSAGVDGFVVYSVCDDDPYLQAVLQ
Mb3606c|M.bovis_AF2122/97 EELGQGLQLVSVGSSRSLADGTAAVLGAGVDGFVVYSVGDDDPYLQVVLQ
Rv3575c|M.tuberculosis_H37Rv EELGQGLQLVSVGSSRSLADGTAAVLGAGVDGFVVYSVGDDDPYLQVVLQ
Mflv_1457|M.gilvum_PYR-GCK EAVGQGLLLVAVGPNRSVAEGSAAVLAAGVDGFVVYSASDDDPYLPAVME
Mvan_5317|M.vanbaalenii_PYR-1 EAVGQGLLLVAVGPNRSVADGSAAVLAAGVDGFVVYSASDDDPYLPAVLQ
MSMEG_6736|M.smegmatis_MC2_155 IEANQRGFFLAVAP-------AAMQLDVAHDGLIAVDPAEGDPLVESARQ
MAB_2023c|M.abscessus_ATCC_199 AALGLDLTLIGRHLT-----GENRSRPPQVDGIIAVDPVPGDAALESLLT
. ::. **::. . .*. :
MMAR_5070|M.marinum_M RRLPVVVVDQPKELAG---VSRVGIDDRAAMRKIADYVLGLGHRQIGLLT
MUL_4146|M.ulcerans_Agy99 RRLPVVVVDQPKELAG---VSRVGIDDRAAMRKIADYVLSLGHRQIGLLT
MAV_0585|M.avium_104 RRLPVVVVDQPKGLTG---VSRVGIDDRAAMRELADYVLGLGHREIGLLT
Mb3606c|M.bovis_AF2122/97 RRLPVVVVDQPKDLSG---VSRVGIDDRAAMRELAGYVLGLGHRELGLLT
Rv3575c|M.tuberculosis_H37Rv RRLPVVVVDQPKDLSG---VSRVGIDDRAAMRELAGYVLGLGHRELGLLT
Mflv_1457|M.gilvum_PYR-GCK RHLPVVVVDQPRDVPG---ASQVRIDDRAAMRSLAEHVIDLGHREIGLLT
Mvan_5317|M.vanbaalenii_PYR-1 RHLPVVVVDQPRDVAG---TSRVCIDDRAAMRRLAEHVIELGHREIGLLT
MSMEG_6736|M.smegmatis_MC2_155 RGTPASTVGR-TASDA---ASWVDNDWAGVVGDVLDHLERGGARRP----
MAB_2023c|M.abscessus_ATCC_199 SNVPIVTVGRILDKDVSHHAAEIEIDHYRMVTLLLDAIRAAGGKRPALA-
* .*.: .: : * : : : * :.
MMAR_5070|M.marinum_M MRLGRDRRQD-----LVDAERLKSPTFDVQRERITGVWEAMTAAGVDPES
MUL_4146|M.ulcerans_Agy99 MRLGRDRRQD-----LVDAERLKSPTFDVQRERITGVWEAMTAAGVDPES
MAV_0585|M.avium_104 MRLGRDRRQG-----LVDAERLRSPAFDVQRERITGVWEAMTAAGVDPDS
Mb3606c|M.bovis_AF2122/97 MRLGRDRRQD-----LVDAERLRSPTFDVQRERIVGVWEAMTAAGVDPDS
Rv3575c|M.tuberculosis_H37Rv MRLGRDRRQD-----LVDAERLRSPTFDVQRERIVGVWEAMTAAGVDPDS
Mflv_1457|M.gilvum_PYR-GCK MRLGRDWPHG-PGPALADPERVRAPNFHVQCERIHGVYDAMTAAGLDPAS
Mvan_5317|M.vanbaalenii_PYR-1 MRLGRDRPHGGSTPVLADPERLRTPHFHVQGERIRGVYDAMTAAGLDPGS
MSMEG_6736|M.smegmatis_MC2_155 --------------MLIAPDSAASYIGSVEREFVS----RCRRHGYAPRS
MAB_2023c|M.abscessus_ATCC_199 ---------------ALDQGADSSYVFDVSR----GYQEWCAKAGVVPLA
: *. * * :
MMAR_5070|M.marinum_M LTVVESYEHLPTSGGDAAKVALEANPRITALMCTADILALSAMDYLRGHG
MUL_4146|M.ulcerans_Agy99 LTVVESYEHLPTSGGDAAKVALEANPRITALMCTADILALSAMDYLRGHG
MAV_0585|M.avium_104 LTVVESYEHLPESGGAAAKVALEANPRITALMCTADILALSAMDYLRAHG
Mb3606c|M.bovis_AF2122/97 LTVVESYEHLPTSGGTAAKVALQANPRLTALMCTADILALSAMDYLRAHG
Rv3575c|M.tuberculosis_H37Rv LTVVESYEHLPTSGGTAAKVALQANPRLTALMCTADILALSAMDYLRAHG
Mflv_1457|M.gilvum_PYR-GCK LTLVESYEHLPTSGGAGADIALEANPRITALMCTADVLALSAMDHLRAKG
Mvan_5317|M.vanbaalenii_PYR-1 LTVVESYEHLPSSGGAGADVALDANPRITALMCTADVLALSAMDHLRAKG
MSMEG_6736|M.smegmatis_MC2_155 ARIAGAFN--PAAARAAVRDILDGPDRPDALFVGLDQLALAAELAATDLG
MAB_2023c|M.abscessus_ATCC_199 TRLSATPTDVELAQAIRGIVEHQG---IDALVVGAQGLAARSLPVLQSLG
: : : :. **. : ** : *
MMAR_5070|M.marinum_M IYVPGQMTVTGF-DGVPEAIS-RGLTTVSQPSLQKGRRAGELLQNPPRS-
MUL_4146|M.ulcerans_Agy99 IYVPGQMTVTGF-DGVPEAIS-RGLTTVSQPSLQKGRRAGELLQNPPRS-
MAV_0585|M.avium_104 VYVPGQLTVTGF-DGVPDAIS-RGLTTVSQSSLHKGRRAGELLLKPARS-
Mb3606c|M.bovis_AF2122/97 IYVPGQMTVTGF-DGVPEALS-RGLTTVAQPSLHKGHRAGELLLKPPRS-
Rv3575c|M.tuberculosis_H37Rv IYVPGQMTVTGF-DGVPEALS-RGLTTVAQPSLHKGHRAGELLLKPPRS-
Mflv_1457|M.gilvum_PYR-GCK IYVPGQMTVTGF-DGVPEARQ-RGLTTVAQPGVEKGRRAGELLHNPPRS-
Mvan_5317|M.vanbaalenii_PYR-1 IYVPGQMTVTGF-DGVPEARR-RGLTTVVQPSVEKGRRAGELLHHPPRS-
MSMEG_6736|M.smegmatis_MC2_155 LRVPEDLMLVNLGDGAAVALAPVPISVVELHAEEMGRAAVRMLVDQIEQN
MAB_2023c|M.abscessus_ATCC_199 HEVGSNFHLGTLVGDPATELTNPDIHAVDLRPREFGHQAVTFLHDIIAGR
* :: : : .. . : .* . *: * :* .
MMAR_5070|M.marinum_M -GLPVVELLDTELIRGRTAGPPA-------
MUL_4146|M.ulcerans_Agy99 -GLPVVELLDTELIRGRTAGPPA-------
MAV_0585|M.avium_104 -GLPVVELLDTELIRGRTAGPPA-------
Mb3606c|M.bovis_AF2122/97 -GLPVIEVLDTELVRGRTAGPPA-------
Rv3575c|M.tuberculosis_H37Rv -GLPVIEVLDTELVRGRTAGPPA-------
Mflv_1457|M.gilvum_PYR-GCK -GLPVVEVLDTEVIRGRTSGPPA-------
Mvan_5317|M.vanbaalenii_PYR-1 -GLPVIEVLDTEMVRGRTSGPPA-------
MSMEG_6736|M.smegmatis_MC2_155 -AEPRHEVVPAHLVVRASSRG---------
MAB_2023c|M.abscessus_ATCC_199 ASANDRRTHQARLKIAGVSSPPAIRRAMSD
. . :.: :