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MSGATVGAREITIRGVVLGALITLVFTAANVYLGLRVGLTFATSIPAAVISMGVLRLFANHSVVENNIVQ TIASAAGTLSSIIFVLPALLMIGWWSGFPYWTTAAVCALGGILGVMYSIPLRRALVTGSDLPYPEGVAGA EVLKIGDSAREMEHNRRGIGVIALGAAAAAGYALLASLRVINNSLSATFRVGSGATMIGASLSLALIGVG HLVGVTVGVAMIVGLAIAFGVMLPIRTAGQLPPDGDYAVAVARIFSTDVRFIGAGAIAVAAAWTFLKILG PILRGIADAAVSARTRRRGQAVGQTERDIPIHIVAMVVLLSLIPIGWLLADFTDGTPLDDRRPGAIAAGV LLVLVIGLMVAAVCGYMAGLIGSSNSPISGVGILVVVLAGLLIKTAYGPATGSQIPALVAYTVFTAALVF GVATISNDNLQDLKTGQLVGATPWKQQVALIIGVLVGSVVMAPILQLMQAGFGFQGAPGATANALAAPQA ALMSALAKGVFGGSLNWSLVGVGALTGVIAVALDETLAKTTTNLRLPPLAVGMGMYLSAALTLMIPIGAF LGRIYDSWARWSGDDDERKKRLGVMLATGLIVGESLYGVLFAVIVATTGKEEPLAMVGDGFRFASQPLGA IVFAGLLAWLYQRTRVTASYRLAAPAGSSKPLPDLPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2395 | - | - | 100% (667) | PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2417 | - | 0.0 | 99.81% (516) | hypothetical protein Mb2417 |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3714 | - | 0.0 | 75.26% (667) | hypothetical protein MMAR_3714 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1311 | - | 0.0 | 64.43% (655) | oligopeptide transporter, OPT family protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1284 | - | 6e-05 | 24.93% (357) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2395|M.tuberculosis_H37Rv ------MSGATVGAREITIRGVVLGALITLVFTAANVYLGLRVGLTFATS
Mb2417|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3714|M.marinum_M ------MSGALGSTREITTRGIILGGLITLVFTAANVYLGLKVGLTFATS
MSMEG_1311|M.smegmatis_MC2_155 MTSESTATPATPTLRELTVRGILLGGVITLVFTAANVYLGLKVGLTFATA
Mvan_1284|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2395|M.tuberculosis_H37Rv IPAAVISMGVLRLFANHSVVENNIVQTIASAAGTLSSIIFVLPALLMIGW
Mb2417|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3714|M.marinum_M IPAAVISMGVLRLFANHSIVENNIVQTIASAAGTLSAIIFVLPALIMIGW
MSMEG_1311|M.smegmatis_MC2_155 IPAAVISMAILRNFRDHSIVENNIVQTVASAAGTLSAIIFVLPGLVMIGW
Mvan_1284|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2395|M.tuberculosis_H37Rv WSGFPYWTTAAVCALGGILGVMYSIPLRRALVTGSDLPYPEGVAGAEVLK
Mb2417|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3714|M.marinum_M WSGFPYWTTVAVCGFGGLLGVMYSIPLRRALVTGSDLPYPEGVAGAEVLK
MSMEG_1311|M.smegmatis_MC2_155 WTGFPYWITVAVCAVGGILGVMYSIPLRRALVTGSDLPYPEGVAAAEVLK
Mvan_1284|M.vanbaalenii_PYR-1 ----------MKWILAAVATALFCVQIDYFAMN---LALPR---------
Rv2395|M.tuberculosis_H37Rv IGDSAREMEHNRRGIGVIALGAAAAAGYALLASLRVINNSLSATFRVGSG
Mb2417|M.bovis_AF2122/97 -------MEHNRRGIGVIALGAAAAAGYALLASLRVINNSLSATFRVGSG
MMAR_3714|M.marinum_M IGASARGAEENRRGLSVIALGAVTAAGYSLLAALKVISNSLAVTFRLGSG
MSMEG_1311|M.smegmatis_MC2_155 VGERTEGAEDNRIGLRIITFGSIVSVAFALLANLKVLANSITAYFRVGAG
Mvan_1284|M.vanbaalenii_PYR-1 --------IAQEFGESPSDLQWVISVYMLALGAFMVPAGRMGDIF--GRR
:. * : :. *. : * . : * *
Rv2395|M.tuberculosis_H37Rv ATMIGASLSLALIGVGHLVGVTVGVAMIVGLAIAFGVMLPIRTAGQLPPD
Mb2417|M.bovis_AF2122/97 ATMIGASLSLALIGVGHLVGVTVGVAMIVGLAIAFGVMLPIRTAGQLPPD
MMAR_3714|M.marinum_M ATMAGASLSLALVGVGHLVGLGVGIAMIVGVLISYGVLLPMRTAGQLPQD
MSMEG_1311|M.smegmatis_MC2_155 GSMFGASLSFALIGVGHLVGMTVGIAMLVGLVISFGIILPFRTIGDFAGS
Mvan_1284|M.vanbaalenii_PYR-1 RALLTGVALFGGASVACALAPSVSLLVAFRAVQGLGAALIFPVSVSVLTN
:: . :. .*. :. *.: : . . * * : . .. .
Rv2395|M.tuberculosis_H37Rv GDYAVAVARIFSTDVRFIGAGAIAVAAAWTFLKILGPILRGIADAAVSAR
Mb2417|M.bovis_AF2122/97 GDYAVAVARIFSTDVRFIGAGAIAVAAAWTFLKILGPILRGIADAAVSAR
MMAR_3714|M.marinum_M GALADFVSRTFSSDVRFIGAGAIAVAAVWTFLKIAGPIMAGIAEAAVSAR
MSMEG_1311|M.smegmatis_MC2_155 ESVADVISSAFANEVRFVGAGAIAVGAVWTLLKILRPIVKGITEALVSAR
Mvan_1284|M.vanbaalenii_PYR-1 AYDAAKAGRAIGLAYGIAGLG-----------NAAGPLVGGLLTGTVGWR
* . :. : * * : *:: *: . *. *
Rv2395|M.tuberculosis_H37Rv TRRRGQAVGQTERDIPIHIVAMVVLLSLIPIGWLLADFTDGTPLDDRRPG
Mb2417|M.bovis_AF2122/97 TRRRGQAVGQTERDIPIHIVAMVVLLSLIPIGWLLADFTDGTPLDDRRPG
MMAR_3714|M.marinum_M TRRRGEAVDLHERDIPIQVVGLVVLVSLIPIGLLLGDFTDHTPIAGRAGS
MSMEG_1311|M.smegmatis_MC2_155 ERREGQLVDITQRDIPFPIVVATIVVMLLPIAVLLWEFSRGTVLQGSSAG
Mvan_1284|M.vanbaalenii_PYR-1 ------------------------WIFWLNVPLALASFVLGARHITESFD
: : : * .* : .
Rv2395|M.tuberculosis_H37Rv AIAAGVLLVLVIGLMVAAVCGYMAGLIGSSNSPISGVGILVVVLAGLLIK
Mb2417|M.bovis_AF2122/97 AIAAGVLLVLVIGLMVAAVCGYMAGLIGSSNSPISGVGILVVVLAGLLIK
MMAR_3714|M.marinum_M IIAVSLLLIVTIGLVVASVCGYMAGLIGSSNSPISGVGILVVLLAALLIK
MSMEG_1311|M.smegmatis_MC2_155 IIVASVVFVFVIGLVIAAVCGYMAGLIGSSNSPISGVGILTVLIAALLIK
Mvan_1284|M.vanbaalenii_PYR-1 ETAPRRIDITGLALVTAGIALFTLAFDRAPDWGWLSVPTLGVFTGAVLAL
. : : :.*: *.:. : .: :.: .* * *. ..:*
Rv2395|M.tuberculosis_H37Rv TAYGPATGSQIPALVAYTVFTAALVFGVATISNDNLQDLKTGQLVGATPW
Mb2417|M.bovis_AF2122/97 TAYGPATGSQIPALVAYTVFTAALVFGVATISNDNLQDLKTGQLVGATPW
MMAR_3714|M.marinum_M WTYGPASDAQTPALVAYAVFTAAVIFGVATISNDNLQDLKTGQLVGATPW
MSMEG_1311|M.smegmatis_MC2_155 IVFGPTNDDQATALVAFTLFAAAITFGVATISNDNLQDLKTGQLVGATPW
Mvan_1284|M.vanbaalenii_PYR-1 AVFVAVENRVRRPLIDLSLFRAG-RFTILVVAG----------------T
.: .. . .*: ::* *. * : .::.
Rv2395|M.tuberculosis_H37Rv KQQVALIIGVLVGSVVMAPILQLMQAGFGFQGAPGATANALAAPQAALMS
Mb2417|M.bovis_AF2122/97 KQQVALIIGVLVGSVVMAPILQLMQAGFGFQGAPGATANALAAPQAALMS
MMAR_3714|M.marinum_M KQQVALVIGVTIGAAVMAPVLQLMQSAFGFQGAPGATGNALAAPQAALIS
MSMEG_1311|M.smegmatis_MC2_155 KQQVALVIGVLFGSAIIPPVLELMQTAFGFLGAPGASENALAAPQAALIS
Mvan_1284|M.vanbaalenii_PYR-1 VANVAYAVVIFLSTLELQQVRGLDPLAAGLVFLGPSTG-------AAIGG
:** : : ..: : : * . *: :: **: .
Rv2395|M.tuberculosis_H37Rv ALAKGVFGGSLNWSLVGVGALTGVIAVALDETLAKTTTNLRLPPLAVGMG
Mb2417|M.bovis_AF2122/97 ALAKGVFGGSLNWSLVGVGALTGVIAVALDETLAKTTTNLRLPPLAVGMG
MMAR_3714|M.marinum_M ALAKGVFGGSLNWSLVGLGALIGIVVVVVDEVLTRTTATLRLPPLAVGMG
MSMEG_1311|M.smegmatis_MC2_155 SLAKGVFGGSLDWSLIGLGAAIGVVVVIIDEILHRTSR-FALPPLAVGMG
Mvan_1284|M.vanbaalenii_PYR-1 VMAGRLATGRSPVAVMGN---------------TSVVAALCLAALAAGGP
:* : * :::* . : *..**.*
Rv2395|M.tuberculosis_H37Rv MYLSAALTLMIPIGAFLGRIYDSWARWSGDDDERKKRLGVMLATGLIVGE
Mb2417|M.bovis_AF2122/97 MYLPAALTLMIPIGAFLGRIYDSWARWSGDDDERKKRLGVMLATGLIVGE
MMAR_3714|M.marinum_M MYLPISLTLVIPVGAVLGRIYDSWAQRSGDEDESKRRMGVMLATGLIVGE
MSMEG_1311|M.smegmatis_MC2_155 MYLPMSLILVIAIGAVIGYVYNRWAIRTGGDVQRKKRLGVLLATGLIVGE
Mvan_1284|M.vanbaalenii_PYR-1 WWFHVAALSACGFSLGLVYAFTTVATQAVVRPERAGEAAGVTLTALVTAG
:: : .. : : * : : . . : *.*:..
Rv2395|M.tuberculosis_H37Rv SLYGVLFAVIVATTGKEEPLAMVGDGFRFASQPLGAIVFAGLLAWLYQRT
Mb2417|M.bovis_AF2122/97 SLYGVLFAVIVATTGKEEPLAMVGDGFRFASQPLGAIVFAGLLAWLYQRT
MMAR_3714|M.marinum_M SLFGVAFAGIVVATGTEDPLAILGDGFTHWAELLGLFVFAAMIALLYRYV
MSMEG_1311|M.smegmatis_MC2_155 SLYGVVFAGIVAGTGNEDPLAIFTGNDGNFAQIFGIVAFAAVILWLYKRT
Mvan_1284|M.vanbaalenii_PYR-1 -GVGIAMAATIFEVLQREGMSPAAAIAVILGAVSALLLPAGAAVLLIKAP
*: :* : . .: :: . . . *. * :
Rv2395|M.tuberculosis_H37Rv RVTASYRLAAPAGSSKPLPDLPG
Mb2417|M.bovis_AF2122/97 RVTASYRLAAPAGSSKPLPDLPG
MMAR_3714|M.marinum_M RAAASYRPTTPGQEPEPLSGRAG
MSMEG_1311|M.smegmatis_MC2_155 QTLSSREVGAKSGQ---------
Mvan_1284|M.vanbaalenii_PYR-1 A----------------------