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MTSDVHDATDGVTETALDDEQSTRRIAELYATDPEFAAAAPLPAVVDAAHKPGLRLAEILQTLFTGYGDR PALGYRARELATDEGGRTVTRLLPRFDTLTYAQVWSRVQAVAAALRHNFAQPIYPGDAVATIGFASPDYL TLDLVCAYLGLVSVPLQHNAPVSRLAPILAEVEPRILTVSAEYLDLAVESVRDVNSVSQLVVFDHHPEVD DHRDALARAREQLAGKGIAVTTLDAIADEGAGLPAEPIYTADHDQRLAMILYTSGSTGAPKGAMYTEAMV ARLWTMSFITGDPTPVINVNFMPLNHLGGRIPISTAVQNGGTSYFVPESDMSTLFEDLALVRPTELGLVP RVADMLYQHHLATVDRLVTQGADELTAEKQAGAELREQVLGGRVITGFVSTAPLAAEMRAFLDITLGAHI VDGYGLTETGAVTRDGVIVRPPVIDYKLIDVPELGYFSTDKPYPRGELLVRSQTLTPGYYKRPEVTASVF DRDGYYHTGDVMAETAPDHLVYVDRRNNVLKLAQGEFVAVANLEAVFSGAALVRQIFVYGNSERSFLLAV VVPTPEALEQYDPAALKAALADSLQRTARDAELQSYEVPADFIVETEPFSAANGLLSGVGKLLRPNLKDR YGQRLEQMYADIAATQANQLRELRRAAATQPVIDTLTQAAATILGTGSEVASDAHFTDLGGDSLSALTLS NLLSDFFGFEVPVGTIVNPATNLAQLAQHIEAQRTAGDRRPSFTTVHGADATEIRASELTLDKFIDAETL RAAPGLPKVTTEPRTVLLSGANGWLGRFLTLQWLERLAPVGGTLITIVRGRDDAAARARLTQAYDTDPEL SRRFAELADRHLRVVAGDIGDPNLGLTPEIWHRLAAEVDLVVHPAALVNHVLPYRQLFGPNVVGTAEVIK LALTERIKPVTYLSTVSVAMGIPDFEEDGDIRTVSPVRPLDGGYANGYGNSKWAGEVLLREAHDLCGLPV ATFRSDMILAHPRYRGQVNVPDMFTRLLLSLLITGVAPRSFYIGDGERPRAHYPGLTVDFVAEAVTTLGA QQREGYVSYDVMNPHDDGISLDVFVDWLIRAGHPIDRVDDYDDWVRRFETALTALPEKRRAQTVLPLLHA FRAPQAPLRGAPEPTEVFHAAVRTAKVGPGDIPHLDEALIDKYIRDLREFGLI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5739 | - | - | 100% (1173) | putative long-chain fatty-acid--CoA ligase |
| M. smegmatis MC2 155 | MSMEG_2956 | - | 0.0 | 55.70% (1167) | NAD dependent epimerase/dehydratase family protein |
| M. smegmatis MC2 155 | MSMEG_0402 | - | e-147 | 36.19% (1086) | linear gramicidin synthetase subunit D |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2621 | fadD9 | 0.0 | 55.11% (1174) | fatty-acid-CoA ligase |
| M. gilvum PYR-GCK | Mflv_2962 | - | 1e-28 | 25.21% (591) | AMP-dependent synthetase and ligase |
| M. tuberculosis H37Rv | Rv2590 | fadD9 | 0.0 | 55.20% (1174) | fatty-acid-CoA ligase |
| M. leprae Br4923 | MLBr_00484 | fadD9 | 0.0 | 53.37% (1171) | putative acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_3367 | - | 0.0 | 59.71% (1159) | putative fatty-acid-CoA ligase |
| M. marinum M | MMAR_2117 | fadD9 | 0.0 | 54.82% (1171) | fatty-acid-CoA ligase FadD9 |
| M. avium 104 | MAV_3471 | - | 0.0 | 55.27% (1176) | putative acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_1879 | fadD9 | 1e-146 | 51.25% (558) | PROBABLE FATTY-ACID-CoA LIGASE FADD9 (FATTY-ACID-CoA |
| M. ulcerans Agy99 | MUL_1722 | - | 0.0 | 54.48% (1171) | fatty-acid-CoA ligase FadD9 |
| M. vanbaalenii PYR-1 | Mvan_2578 | - | 0.0 | 54.90% (1173) | thioester reductase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5739|M.smegmatis_MC2_155 ---MTSDVHDATDGVTETALDDEQSTRRIAELYATDPEFAAAAPLPAVVD
MAB_3367|M.abscessus_ATCC_1997 ----------MTAG----------AAARVAKLFESDPQFRAAMPDPAVMD
Mb2621|M.bovis_AF2122/97 --------------MS--INDQR-LTRRVEDLYASDAQFAAASPNEAITQ
Rv2590|M.tuberculosis_H37Rv --------------MS--INDQR-LTRRVEDLYASDAQFAAASPNEAITQ
MMAR_2117|M.marinum_M --------------MSPITREER-LERRIQDLYANDPQFAAAKPATAITA
MUL_1722|M.ulcerans_Agy99 --------------MSPITREER-LERRIQDLYANDPQFAAAKPVTAITA
MLBr_00484|M.leprae_Br4923 MWRQQSISHRKESVMSTITKQEKQLARRVDDLTANDPQFAAAKPDPAVAA
MAV_3471|M.avium_104 --------------MSTATHDER-LDRRVHELIATDPQFAAAQPDPAITA
Mvan_2578|M.vanbaalenii_PYR-1 --------------MSTDTREDR-LARRIADLYATDPQFAAAAPDDAISH
TH_1879|M.thermoresistible__bu --------------------------------------------------
Mflv_2962|M.gilvum_PYR-GCK ---------------------------MTAREFTVPAPFTVEERDNIVGA
MSMEG_5739|M.smegmatis_MC2_155 AAHKPGLRLAEILQTLFTGYGDRPALGYRARELATDEG-GRTVTRLLPRF
MAB_3367|M.abscessus_ATCC_1997 SLLAPGLRLSQVLHALLSGYAERPVMGFRSRESVVDTATGRTVDRLLPAF
Mb2621|M.bovis_AF2122/97 AIDQPGVALPQLIRMVMEGYADRPALGQRALRFVTDPDSGRTMVELLPRF
Rv2590|M.tuberculosis_H37Rv AIDQPGVALPQLIRMVMEGYADRPALGQRALRFVTDPDSGRTMVELLPRF
MMAR_2117|M.marinum_M AIERPGLPLPQIIETVMTGYADRPALAQRSVEFVTDAGTGHTTLRLLPHF
MUL_1722|M.ulcerans_Agy99 AIERPGLPLPQIIETVMTGYADRPALAQRSVEFVTDAGTGHTTLRLLPHF
MLBr_00484|M.leprae_Br4923 ALAQPGLRLPQIIQTALDGYAERPALGQRVAEFTKDPKTGRTSMELLPSF
MAV_3471|M.avium_104 ALEQPGLRLPQIIRTVLDGYADRPALGQRVVEFVTDAKTGRTSAQLLPRF
Mvan_2578|M.vanbaalenii_PYR-1 AIDQPGTHLPVIVQTVLDGYAERPALGQRAVRFVTDPATGRTTTELLPRF
TH_1879|M.thermoresistible__bu --------------------------------------------------
Mflv_2962|M.gilvum_PYR-GCK VFTHERDDPDHVIFQRLVDGKWIDVTARQAAGQIRSAARGLIAEG-----
MSMEG_5739|M.smegmatis_MC2_155 DTLTYAQVWSRVQAVAAALRHNFAQPIYPGDAVATIGFASPDYLTLDLVC
MAB_3367|M.abscessus_ATCC_1997 ETITYGQLLEDISAILAEWQHG-DIPMGAGDFIATIGFSSPDYVTLDLAT
Mb2621|M.bovis_AF2122/97 ETITYRELWARAGTLAT--ALSAEPAIRPGDRVCVLGFNSVDYTTIDIAL
Rv2590|M.tuberculosis_H37Rv ETITYRELWARAGTLAT--ALSAEPAIRPGDRVCVLGFNSVDYTTIDIAL
MMAR_2117|M.marinum_M ETISYGELWDRISALAD--VLSTEQTVKPGDRVCLLGFNSVDYATIDMTL
MUL_1722|M.ulcerans_Agy99 ETISYGELWDRISALAD--VLSTEQTVKPSDRVCLLGFNSVDYATIDMTL
MLBr_00484|M.leprae_Br4923 ETITYRQLGDRVGALAR--AWRHD-LLHAGYRVCVLGFNSVDYAIIDMAL
MAV_3471|M.avium_104 ETITYGEVAQRVSALGR--ALSDD-AVHPGDRVCVLGFNSVDYATIDMAL
Mvan_2578|M.vanbaalenii_PYR-1 ETITYAELSRRIHAVTA--ALTDV---HPGDRVAVLGFTSIDYTTVDMAL
TH_1879|M.thermoresistible__bu --------------------------------------------------
Mflv_2962|M.gilvum_PYR-GCK --------------------------VQAGDRVALLSATRYEWPILDFAI
MSMEG_5739|M.smegmatis_MC2_155 AYLGLVSVPLQHNAPVSRLAPILAEVEPRILTVSAEYLDLAVESVRDVNS
MAB_3367|M.abscessus_ATCC_1997 LMNGSVSIPLQHNTSVAQLRMMLEETSPRLVAASADCLDLAVEAAVGLTD
Mb2621|M.bovis_AF2122/97 IRLGAVSVPLQTSAPVTGLRPIVTETEPTMIATSIDNLGDAVEV-LAGHA
Rv2590|M.tuberculosis_H37Rv IRLGAVSVPLQTSAPVTGLRPIVTETEPTMIATSIDNLGDAVEV-LAGHA
MMAR_2117|M.marinum_M ARLGAVAVPLQTSAAITQLQPIVAETQPTMIAASVDALADATELALSGQT
MUL_1722|M.ulcerans_Agy99 ARLGAVAVPLQTSAAITQLQPIVAETQPTMIAASVDALADATELALSGQT
MLBr_00484|M.leprae_Br4923 GVIGAVAVPLQTSAAITQLQSIVTETEPSMIATSVNQLPDTVELIL-SGQ
MAV_3471|M.avium_104 GAIGAVSVPLQTSAAISSLQPIVAETEPTLIASSVNQLSDAVQLITGAEQ
Mvan_2578|M.vanbaalenii_PYR-1 AMLGAVAVPLQTSAPATTVRPIVAETEPVVIASSVDALTDAVGLALDAPT
TH_1879|M.thermoresistible__bu --------------------------------------------------
Mflv_2962|M.gilvum_PYR-GCK LSIGAVTVPIYETSSAEQVQFVLADSGAVAAIAETDAHAAHIEAQRDTLP
MSMEG_5739|M.smegmatis_MC2_155 V-SQLVVFDHHPEVDDHRDALARAREQL--AGKGIAVTTLDAIADEG---
MAB_3367|M.abscessus_ATCC_1997 L-RRVVVFDYRAETDDHREKLATARERLHAAGMDVVVEPLAEVIGRG---
Mb2621|M.bovis_AF2122/97 P-ARLVVFDYHGKVDTHREAVEAARARL--AGS-VTIDTLAELIER----
Rv2590|M.tuberculosis_H37Rv P-ARLVVFDYHGKVDTHREAVEAARARL--AGS-VTIDTLAELIER----
MMAR_2117|M.marinum_M A-TRVLVFDHHRQVDAHRAAVESARERL--AGS-AVVETLAEAIARGDVP
MUL_1722|M.ulcerans_Agy99 A-TRVLVFDHHRQVDAHRAAVESARERL--AGS-AVVETLAEAIARGDVP
MLBr_00484|M.leprae_Br4923 APAKLVVFDYHPEVDEQHDAVATARARL--ADSSVVVESLTEVLGRG---
MAV_3471|M.avium_104 APTRLVVFDYHPQVDDQREAVQDAAARL--SGTGVAVQTLAELLERG---
Mvan_2578|M.vanbaalenii_PYR-1 V-TRLVVFDHRAGVDDHRDALISASDRLRAANSPIEVETITDIVARG---
TH_1879|M.thermoresistible__bu --------------------------------------------------
Mflv_2962|M.gilvum_PYR-GCK ALRRIYVIDGS----------VPALDELAEAGASVDAAAVDERVASIR--
MSMEG_5739|M.smegmatis_MC2_155 AGLPAEPIYTADH-DQRLAMILYTSGSTGAPKGAMYTEAMVARLWTMSFI
MAB_3367|M.abscessus_ATCC_1997 RDLPEPVLYTAGD-DQRTALIMYTSGSTGAPKGAMFTEWTVTRFWSSGAA
Mb2621|M.bovis_AF2122/97 -GRALPATPIADSADDALALLIYTSGSTGAPKGAMYRESQVMSFWRKSSG
Rv2590|M.tuberculosis_H37Rv -GRALPATPIADSADDALALLIYTSGSTGAPKGAMYRESQVMSFWRKSSG
MMAR_2117|M.marinum_M RGASAGSAPGTDVSDDSLALLIYTSGSTGAPKGAMYPRRNVATFWRKRT-
MUL_1722|M.ulcerans_Agy99 RGASAGSAPGTDVSDDSLALLIYTSGSTGAPKGAMYPRRNVATFWRKRT-
MLBr_00484|M.leprae_Br4923 KTLPATPIPVADDSADPLALLIYTSGSTGAPKGAMYLQSNVGKMWRRSDG
MAV_3471|M.avium_104 KDLPAVAEPPADE--DSLALLIYTSGSTGAPKGAMYPQSNVGKMWRRGSK
Mvan_2578|M.vanbaalenii_PYR-1 SKLPVRAQFSADG--DALSLLIYTSGSTGAPKGAMYPQHLVANSWRRLAR
TH_1879|M.thermoresistible__bu --------------------------------------------------
Mflv_2962|M.gilvum_PYR-GCK --------------STDAATLIYTSGTTGRPKGCQLTHSNLLYEIRGAKA
MSMEG_5739|M.smegmatis_MC2_155 TGDPTP----VINVNFMPLNHLGGRIPISTAVQNGGTSYFVPESDMSTLF
MAB_3367|M.abscessus_ATCC_1997 PNRDTP----IINVNFLPLNHLAGRVGLLTAFIPGGTCYFVPESDLSTLF
Mb2621|M.bovis_AF2122/97 WFEPSG--YPSITLNFMPMSHVGGRQVLYGTLSNGGTAYYVAKSDLSTLF
Rv2590|M.tuberculosis_H37Rv WFEPSG--YPSITLNFMPMSHVGGRQVLYGTLSNGGTAYFVAKSDLSTLF
MMAR_2117|M.marinum_M WFEGGY--EPSITLNFMPMSHVMGRQILYGTLCNGGTAYFVAKSDLSTLF
MUL_1722|M.ulcerans_Agy99 WFEGGY--EPSITLNFMPMSHVMGRQILYGTLCNGGTAYFVVKSDLSTLF
MLBr_00484|M.leprae_Br4923 NWFGPT--AASITLNFMPMSHVMGRGILYGTLGNGGTAYFAARSDLSTLL
MAV_3471|M.avium_104 NWFGES--AASITLNFMPMSHVMGRSILYGTLGNGGTAYFAARSDLSTLL
Mvan_2578|M.vanbaalenii_PYR-1 SFWGDLGVFPAITLNFMPMSHVMGRGLLYGTLDAGGTAYFAARSDLSTFL
TH_1879|M.thermoresistible__bu --------------------------------------------------
Mflv_2962|M.gilvum_PYR-GCK CFPEHLA-KGEKLLVFLPLAHVLARALTIGAFSNGVTLGFT--SDIKNLV
MSMEG_5739|M.smegmatis_MC2_155 EDLALVRPTELGLVPRVADMLYQHHLATVDRLVTQ---GADELTAEKQAG
MAB_3367|M.abscessus_ATCC_1997 EDWQLARPTHMGVVPRVVDMLFQHYQTRVDALMAG---GTDVDTADRLAK
Mb2621|M.bovis_AF2122/97 EDLALVRPTELCFVPRIWDMVFAEFHSEVDRRLVD---GADRAALEAQVK
Rv2590|M.tuberculosis_H37Rv EDLALVRPTELCFVPRIWDMVFAEFHSEVDRRLVD---GADRAALEAQVK
MMAR_2117|M.marinum_M EDLALVRPTELTFVPRVWDMVFDEFQSEVDRRLVD---GADRVALEAQVK
MUL_1722|M.ulcerans_Agy99 EDLALVRPTELTFVPRVWDMVFDEFQSEVDRRLVD---GADRVALEAQVK
MLBr_00484|M.leprae_Br4923 EDLKLVRPTELNFVPRIWETLYDESKRAVDRRLANSGSA-DRAAIKAEVM
MAV_3471|M.avium_104 EDLELVRPTELNFVPRIWETLYGEFQRQVERRLSEAGDAGERRAVEAEVL
Mvan_2578|M.vanbaalenii_PYR-1 EDLALVRPTQLSFVPRIWDTIHAEVSQELERRPSD----------ATEVI
TH_1879|M.thermoresistible__bu --------------------------------------------------
Mflv_2962|M.gilvum_PYR-GCK PMFAVFQPTLVVSVPRVFEKVYN---------------------------
MSMEG_5739|M.smegmatis_MC2_155 AELREQVLGGRVITGFVSTAPLAAEMRAFLDITL-GAHIVDGYGLTETGA
MAB_3367|M.abscessus_ATCC_1997 TELREDVLGGRVVAGMLATAPLSPEMKAFLESSL-DFHLLDLYGLTEVGG
Mb2621|M.bovis_AF2122/97 AELRENVLGGRFVMALTGSAPISAEMTAWVESLLADVHLVEGYGSTEAGM
Rv2590|M.tuberculosis_H37Rv AELRENVLGGRFVMALTGSAPISAEMTAWVESLLADVHLVEGYGSTEAGM
MMAR_2117|M.marinum_M AEIRNDVLGGRYTSALTGSAPISDEMKAWVEELL-DMHLVEGYGSTEAGM
MUL_1722|M.ulcerans_Agy99 AEIRNDVLGGRYTSALTGSAPISDEMKAWVEELL-DMHLVEGYGSTEAGM
MLBr_00484|M.leprae_Br4923 DEQRQSLLGGRYIAAMTGSAPTSPELKHGVESLL-EMHLLEGYGSTEAGM
MAV_3471|M.avium_104 AEQRQYLLGGRFTFAMTGSAPISPELRNWVESLL-EMHLMDGYGSTEAGM
Mvan_2578|M.vanbaalenii_PYR-1 ADLRRSLLGGRYVTAMTGSAPLSPEMRAFVENLL-DVHLIDGYGSTEAGA
TH_1879|M.thermoresistible__bu --------------------------------------------------
Mflv_2962|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5739|M.smegmatis_MC2_155 VTRDGVIVRPPVIDYKLIDVPELGYFSTDKPYPRGELLVRSQTLTPGYYK
MAB_3367|M.abscessus_ATCC_1997 VFRDGKISRPPVLDYKLVDVPELGYYTTDKPHPRGELLVKSATATPGYYK
Mb2621|M.bovis_AF2122/97 VLNDGMVRRPAVIDYKLVDVPELGYFGTDQPYPRGELLVKTQTMFPGYYQ
Rv2590|M.tuberculosis_H37Rv VLNDGMVRRPAVIDYKLVDVPELGYFGTDQPYPRGELLVKTQTMFPGYYQ
MMAR_2117|M.marinum_M ILIDGAIRRPAVLDYKLVDVPDLGYFLTDRPHPRGELLVKTDSLFPGYYQ
MUL_1722|M.ulcerans_Agy99 ILIDGAIRRPAVLDYKLVDVPDLGYFLTDRPHPRGELLVKTDSLFPGYYQ
MLBr_00484|M.leprae_Br4923 VLFDGEVQRPPVIDYKLVDVPDLGYFSTDQPYPRGELLLKTQNMFPGYYK
MAV_3471|M.avium_104 VLFDGEIQRPPVVDYKLVDVPDLGYFSTDRPHPRGELLLRTENMFPGYYK
Mvan_2578|M.vanbaalenii_PYR-1 VFVDGRVQRPPVIDYKLVDVADLGYFSTDRPHPRGELLVKSETLFPGYYK
TH_1879|M.thermoresistible__bu --------------------------------------------------
Mflv_2962|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5739|M.smegmatis_MC2_155 RPEVTASVFDRDGYYHTGDVMAETAPDHLVYVDRRNNVLKLAQGEFVAVA
MAB_3367|M.abscessus_ATCC_1997 RPDVTAEVFDADGYYRTGDVMAEVAPDQLVYVDRRNNVIKLAQGEFVAVA
Mb2621|M.bovis_AF2122/97 RPDVTAEVFDPDGFYRTGDIMAKVGPDQFVYLDRRNNVLKLSQGEFIAVS
Rv2590|M.tuberculosis_H37Rv RPDVTAEVFDPDGFYRTGDIMAKVGPDQFVYLDRRNNVLKLSQGEFIAVS
MMAR_2117|M.marinum_M RAEVTADVFDADGFYRTGDIMAEVGPEQFVYLDRRNNVLKLSQGEFVTVS
MUL_1722|M.ulcerans_Agy99 RAEVTADVFDADGFYRTGDIMAEVGPEQFVYLDRRNNVLKLSQGEFVTVS
MLBr_00484|M.leprae_Br4923 RPEVTATVFDSDGYYQTGDIVAEVGPDRLVYVDRRNNVLKLAQGQFVTVA
MAV_3471|M.avium_104 RAETTAGVFDEDGYYRTGDVFAEIAPDRLVYVDRRNNVLKLAQGEFVTLA
Mvan_2578|M.vanbaalenii_PYR-1 RPDVTAEMFDEDGYYRTGDIVAETGADQLTYLDRRNNVLKLSQGEFVTVS
TH_1879|M.thermoresistible__bu --------------------------------------------------
Mflv_2962|M.gilvum_PYR-GCK ----------------TAELNAETGGKGKIFTAAANTAIEYS--------
MSMEG_5739|M.smegmatis_MC2_155 NLEAVFSGAALVRQIFVYGNSERSFLLAVVVPTPEALEQY-DPAALKAAL
MAB_3367|M.abscessus_ATCC_1997 NLETVYVGAPLVRQIFVYGNSERAYLLAVVVPTEEALRAHPDPVELKNSI
Mb2621|M.bovis_AF2122/97 KLEAVFGDSPLVRQIFIYGNSARAYPLAVVVPSGDALSRH-GIENLKPVI
Rv2590|M.tuberculosis_H37Rv KLEAVFGDSPLVRQIFIYGNSARAYPLAVVVPSGDALSRH-GIENLKPVI
MMAR_2117|M.marinum_M KLEAVFGDSPLVRQIYIYGNSARAYLLAVIVPTQEALDAV-PVEELKARL
MUL_1722|M.ulcerans_Agy99 KLEAVFGDSPLVRQIYIYGNSARAYLLAVIVPTQEALDAV-PVEELKARL
MLBr_00484|M.leprae_Br4923 KLEAAFSNSPLVRQIYIYGNSAHPYLLAVVVPTEDALATN-DIEVLKPLI
MAV_3471|M.avium_104 KLEAVFGNSPLIRQIYVYGNSAQPYLLAVVVPTEEALASG-DPETLKPKI
Mvan_2578|M.vanbaalenii_PYR-1 RLEAVFGNSPLVRQIYVYGNSARPYLLAVVVPTEAALAG----ADAKAAV
TH_1879|M.thermoresistible__bu -------------------------------------------------V
Mflv_2962|M.gilvum_PYR-GCK ----------------------------------KALDSGG---------
MSMEG_5739|M.smegmatis_MC2_155 ADSLQRTARDAE-LQSYEVPADFIVETEPFSAANGLLSGVGKLLRPNLKD
MAB_3367|M.abscessus_ATCC_1997 RESLQRTARSNH-LHSYELPADFIIETTPFTIESGMLAAVGKPIRPKMIE
Mb2621|M.bovis_AF2122/97 SESLQEVARAAG-LQSYEIPRDFIIETTPFTLENGLLTGIRKLARPQLKK
Rv2590|M.tuberculosis_H37Rv SESLQEVARAAG-LQSYEIPRDFIIETTPFTLENGLLTGIRKLARPQLKK
MMAR_2117|M.marinum_M GDSLQEVAKAAG-LQSYEIPRDFIIETTPWTLENGLLTGIRKLARPQLKK
MUL_1722|M.ulcerans_Agy99 GDSLQEVAKAAG-LQSYEIPRDFIIETTPWTLQNGLLTGIRKLARPQLKK
MLBr_00484|M.leprae_Br4923 IDSLQKVAKEAD-LQSYEVPRDLIVETTPFSLENGLLTGIRKLAWPKLKQ
MAV_3471|M.avium_104 ADSLQQVAKEAG-LQSYEVPRDFIIETTPFSLENGLLTGIRKLAWPKLKQ
Mvan_2578|M.vanbaalenii_PYR-1 AESLQDVAKATG-LQSYEIPRDFLLETTPFTLENGLLTGIRKLARPRLRE
TH_1879|M.thermoresistible__bu GLSXQARARLADRLPAYMVPAAVVVLDRIPLTVNGKLD-RRALPAPEYQR
Mflv_2962|M.gilvum_PYR-GCK --------------------PGLVLKLKHALFDKLVYGKLRAALG-----
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MSMEG_5739|M.smegmatis_MC2_155 RYGQRLEQMYADIAATQANQLRELRRAAATQPVIDTLTQAAATILGTGSE
MAB_3367|M.abscessus_ATCC_1997 HYGDRLEQLYVDLAEARVQELRQLRDTAQQRPVLDTVTEAAQALLGMSAD
Mb2621|M.bovis_AF2122/97 FYGERLERLYTELADSQSNELRELRQSGPDAPVLPTLCRAAAALLGSTAA
Rv2590|M.tuberculosis_H37Rv FYGERLERLYTELADSQSNELRELRQSGPDAPVLPTLCRAAAALLGSTAA
MMAR_2117|M.marinum_M HYGELLEQIYTDLAHGQADELRSLRQSGADAPVLVTVCRAAAALLGGSAS
MUL_1722|M.ulcerans_Agy99 HYGELLEQIYTDLAHGQADELRSLRQSGADAPVLVTVCRAAAALLGGSAS
MLBr_00484|M.leprae_Br4923 HYGARLEQLYADLVEGQANALHVLKQSVANAPVLQTVSRAVGTILGVATT
MAV_3471|M.avium_104 HYGERLEQMYADLAAGQADELAELRRNGAQAPVLQTVSRAAGAMLGSAAS
Mvan_2578|M.vanbaalenii_PYR-1 RYGEQLEALYTMLSEEQADELRELRRSGGERPALETVGRAAGALLGTTAG
TH_1879|M.thermoresistible__bu AD----------------------RYRAPETAVEKTLTEIFAHVLG--LE
Mflv_2962|M.gilvum_PYR-GCK -------------------------------------GRCHAAISGGAPL
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MSMEG_5739|M.smegmatis_MC2_155 VAS-DAHFTDLGGDSLSALTLSNLLSDFFGFEVPVGTIVNPATNLAQLAQ
MAB_3367|M.abscessus_ATCC_1997 AVRPDHHFIDLGGDSLSALTFSNLLRDLFDVEVPVGVITGPAADLRKLAA
Mb2621|M.bovis_AF2122/97 DVRPDAHFADLGGDSLSALSLANLLHEIFGVDVPVGVIVSPASDLRALAD
Rv2590|M.tuberculosis_H37Rv DVRPDAHFADLGGDSLSALSLANLLHEIFGVDVPVGVIVSPASDLRALAD
MMAR_2117|M.marinum_M DVQPDAHFTDLGGDSLSALSFTNLLHEIFDIEVPVGVIVSPANDLQALAD
MUL_1722|M.ulcerans_Agy99 DVQPDAHFTDLGGDSLSALSFTNLLHEIFDIDVPVGVIVSPANDLQALAD
MLBr_00484|M.leprae_Br4923 DLPSNAHFTDLGGDSLSALTFGSLLRELFDIDVPVGVIVSPVNNLVAIAD
MAV_3471|M.avium_104 DLSPDAHFTDLGGDSLSALTFGNLLREIFDVDVPVGVIVSPANDLAAIAS
Mvan_2578|M.vanbaalenii_PYR-1 ELEPSAHFTDLGGDSLSALTFANLLRDIFDVDVPVGVIVSPATDLQALAD
TH_1879|M.thermoresistible__bu RVGVDDSFFDLGGDSISAMRAVAAINTALDTDVAVRTLFEAP-TVRRLSR
Mflv_2962|M.gilvum_PYR-GCK GARLGHFYRGVGLSIYEGYGLT---------ETSAAITVNRVGDLRVG--
. : .:* . .. :... :
MSMEG_5739|M.smegmatis_MC2_155 HIE-----AQRTAGDRRPSFTTVHGAD---ATEIRASELTLDKFIDAETL
MAB_3367|M.abscessus_ATCC_1997 YIQ-----HEREHS--TATAASVHGLD---TTVISATELTLDKFIDAETL
Mb2621|M.bovis_AF2122/97 HIE-----AAR-TGVRRPSFASIHGRS---ATEVHASDLTLDKFIDAATL
Rv2590|M.tuberculosis_H37Rv HIE-----AAR-TGVRRPSFASIHGRS---ATEVHASDLTLDKFIDAATL
MMAR_2117|M.marinum_M YVE-----AARKPGSSRPTFASVHGASNGQVTEVHAGDLSLDKFIDAATL
MUL_1722|M.ulcerans_Agy99 YVE-----AARKPGSSRPTFASVHGASNEQVTEVHAGDLSLDKFIDAATL
MLBr_00484|M.leprae_Br4923 YIE-----RER-QGTKRPTFIAIHGRD---AGKVHASDLTLDKFIDVSTL
MAV_3471|M.avium_104 YIE-----AER-QGSKRPTFASVHGRD---ATVVRAADLTLDKFLDADTL
Mvan_2578|M.vanbaalenii_PYR-1 YVE-----SARRHGSVRPTFESVHGHSGRPGTEVHARDLTLDEFVDAATL
TH_1879|M.thermoresistible__bu QLEGGADTAPQGADLGAVTYESVHGAT---ATEVRAADLTLDRFIDAATL
Mflv_2962|M.gilvum_PYR-GCK ---------------------------------------SVGKLVPGNSM
::..:: ::
MSMEG_5739|M.smegmatis_MC2_155 RAAPGLPKVTTEPRTVLLSGANGWLGRFLTLQWLERLAPVGGTLITIVRG
MAB_3367|M.abscessus_ATCC_1997 HNASQLDVPAGAVATVLLTGANGYLGRFLCLEWLQRLSQTGGQLICLVRG
Mb2621|M.bovis_AF2122/97 AAAPNLPAPSAQVRTVLLTGATGFLGRYLALEWLDRMDLVNGKLICLVRA
Rv2590|M.tuberculosis_H37Rv AAAPNLPAPSAQVRTVLLTGATGFLGRYLALEWLDRMDLVNGKLICLVRA
MMAR_2117|M.marinum_M AEAPRLPAANTQVRTVLLTGATGFLGRYLALEWLERMDLVDGKLICLVRA
MUL_1722|M.ulcerans_Agy99 AEAPRLPAANTQVRTVLLTGATGFLGRYLALEWLERMDLVDGKLICLVRA
MLBr_00484|M.leprae_Br4923 TAAPVLAQPGTEVRTVLLTGATGFLGRYLALKWLERMDLVEGKVIALVRA
MAV_3471|M.avium_104 ASAPNLPKPATEVRTVLLTGATGFLGRYLALEWLERMDMVDGKVIALVRA
Mvan_2578|M.vanbaalenii_PYR-1 AHAPTLPGPRAEVRTVLLTGATGFLGRYLALEWLERMALVGGKLICLVRA
TH_1879|M.thermoresistible__bu RTAADLPRPTGQVQTVLLTGATGFLGRYLLLEWLRRLRRVDDTVICLVRG
Mflv_2962|M.gilvum_PYR-GCK RLG--------EDGELLVRGGVVFNG-YWGNEEETRAVFTDGWFHTGDLG
. :*: *. : * : : * . . . .
MSMEG_5739|M.smegmatis_MC2_155 RDDAAARARLTQAY-DTDPELSRRFAELADRHLRVVAGDIGDPNLGLTPE
MAB_3367|M.abscessus_ATCC_1997 DNADQALARLVAAYGDTDRTLLEEFHTLARRHLRVIAADIAQPRFGVDDA
Mb2621|M.bovis_AF2122/97 RSDEEAQARLDATFDSGDPYLVRHYRELGAGRLEVLAGDKGEADLGLDRV
Rv2590|M.tuberculosis_H37Rv RSDEEAQARLDATFDSGDPYLVRHYRELGAGRLEVLAGDKGEADLGLDRV
MMAR_2117|M.marinum_M KSDTEARARLDKTFDSGDPELLAHYRALAGDHLEVLAGDKGEADLGLDRQ
MUL_1722|M.ulcerans_Agy99 KSDTEARARLEKTFDSGAPELLAHYRALAGDHLEVLAGDKGEADLGLDRQ
MLBr_00484|M.leprae_Br4923 KSNEDARARLDKTFDSGDPKLLAHYQELATDHLEVIAGDKGEVDLELDRQ
MAV_3471|M.avium_104 RSDEEARARLDKTFDSGDPKLLAHYQQLAADHLEVIAGDKGEANLGLRQD
Mvan_2578|M.vanbaalenii_PYR-1 KDDAAARVRLDSTFDSGDPELLRHYRRLAADHLEVIAGDKADADLGLDAR
TH_1879|M.thermoresistible__bu RSDADARQRLEAVFDT-DPALRRHFRELAAERLQVIAGDKGQPNLGLDVQ
Mflv_2962|M.gilvum_PYR-GCK AIDDDG------------------FLTIVGRKKEIIVTAGGKN-------
. : : : .::. ..
MSMEG_5739|M.smegmatis_MC2_155 IWHRLAAEVDLVVHPAALVNHVLPYRQLFGPNVVGTAEVIKLALTERIKP
MAB_3367|M.abscessus_ATCC_1997 TWEQLARDVDKIVHPAALVNHVLPYNQLFGPNVFGTAEVIRLALTTRIKP
Mb2621|M.bovis_AF2122/97 TWQRLADTVDLIVDPAALVNHVLPYSQLFGPNAAGTAELLRLALTGKRKP
Rv2590|M.tuberculosis_H37Rv TWQRLADTVDLIVDPAALVNHVLPYSQLFGPNAAGTAELLRLALTGKRKP
MMAR_2117|M.marinum_M TWQRLADTVDLIVDPAALVNHVLPYSQLFGPNALGTAELLRLALTSKIKP
MUL_1722|M.ulcerans_Agy99 TWQRLADTVDLIVDPAALVNHVLPYSQLFGPNALGTAELLRLALTSKIKP
MLBr_00484|M.leprae_Br4923 TWRRLADTVDLIVDPAALVNHVLPYSELFGPNTLGTAELIRIALTSKQKP
MAV_3471|M.avium_104 VWQRLADTVDVIVDPAALVNHVLPYSELFGPNALGTAELIRLALTSKQKP
Mvan_2578|M.vanbaalenii_PYR-1 TWQRLADTVDLIVDPAALVNHVLPYRQLFAPNVLGTAELLRIALTTRMKP
TH_1879|M.thermoresistible__bu TWRRLAERVDLIVDSAAFVNSVLPYRELFGPNVVGTAELIRFALTAKLKP
Mflv_2962|M.gilvum_PYR-GCK ------------VAPAQLEDRLRAHPLISQAMAVGDQQPFIAALIT----
* .* : : : .: : . . * : : **
MSMEG_5739|M.smegmatis_MC2_155 VTYLSTVSVAMGIP--DFEEDGDIRTVSPVRPLDGGYANGYGNSKWAGEV
MAB_3367|M.abscessus_ATCC_1997 VTYLSTMAVAMTVP--DFDEDGDIRTVSPTRHIDPGYANGYANSKWAGEV
Mb2621|M.bovis_AF2122/97 YIYTSTIAVGEQIPPEAFTEDADIRAISPTRRIDDSYANGYANSKWAGEV
Rv2590|M.tuberculosis_H37Rv YIYTSTIAVGEQIPPEAFTEDADIRAISPTRRIDDSYANGYANSKWAGEV
MMAR_2117|M.marinum_M YSYTSTIGVADQIPPSAFTEDADIRVISATRAVDDSYANGYSNSKWAGEV
MUL_1722|M.ulcerans_Agy99 YSYTSTIGVADQIPPSAFTEDADIRVISATRAVDDSYANGYSNSKWAGEV
MLBr_00484|M.leprae_Br4923 YIYVSTIGVGNQIEPAKFTEDSDIRVISPTRNINNNYANGYGNSKWAGEV
MAV_3471|M.avium_104 YTYVSTIGVGDQIEPGKFVENADIRQMSATRAINDSYANGYGNSKWAGEV
Mvan_2578|M.vanbaalenii_PYR-1 FVYVSTIGVGAGIEPARFTEDADIRQISATRRIDDSYANGYGNSKWAGEV
TH_1879|M.thermoresistible__bu YNFVSTSDIGRQIEPDLFTEDADIRTISPTRTVDASYANGYGNSKWAGEV
Mflv_2962|M.gilvum_PYR-GCK --------------------------------VDTEAFPGWKERHHK---
:: *: : :
MSMEG_5739|M.smegmatis_MC2_155 LLREAHDLCGLPVATFRSDMILAHPRYRGQVNVPDMFTRLLLSLLITGVA
MAB_3367|M.abscessus_ATCC_1997 LLREAHDICGLPVSVFRSDMILTHRRYSGQLNVTDAFTRMLLSLVLTGIA
Mb2621|M.bovis_AF2122/97 LLREAHEQCGLPVTVFRCDMILADTSYTGQLNLPDMFTRLMLSLAATGIA
Rv2590|M.tuberculosis_H37Rv LLREAHEQCGLPVTVFRCDMILADTSYTGQLNLPDMFTRLMLSLAATGIA
MMAR_2117|M.marinum_M LLREAHDLCGLPVAVFRCDMILADTTWAGQLNVPDMFTRMILSLAATGIA
MUL_1722|M.ulcerans_Agy99 LLREAHVLCGLPVAVFRCDMILADTTWAGQLNVPDMFTRMILSLAATGIA
MLBr_00484|M.leprae_Br4923 LLREAHDLCGLPVTVFRCDMILADTSYAGQLNVPDMFTRMMLSLAATGIA
MAV_3471|M.avium_104 LLREAHDLCGLPVAVFRCDMILADTTYAGQLNLPDMFTRLMLSLVATGIA
Mvan_2578|M.vanbaalenii_PYR-1 LLREAHDLCGLPVSVFRCDMILADTTYAGQLNLPDMFTRLIFSLVATGVA
TH_1879|M.thermoresistible__bu LLREAHDLCGLPVAVFRSGMILVDPTYAGQLNVTDTVSRMVLSIVATGVA
Mflv_2962|M.gilvum_PYR-GCK ---------------------ASDASVADLADDPDLLAEIELAVKDANQA
. . : .* .:.: ::: :. *
MSMEG_5739|M.smegmatis_MC2_155 PRSFYIGDG--ERPRAHYPGLTVDFVAEAVTTLGAQ---QREG-----YV
MAB_3367|M.abscessus_ATCC_1997 PRSFYQGDGSGARPRAHYEGLPVDFVTEAITSLGLS---SSEG-----FR
Mb2621|M.bovis_AF2122/97 PGSFYELDAHGNRQRAHYDGLPVEFVAEAICTLGTH---SPDR-----FV
Rv2590|M.tuberculosis_H37Rv PGSFYELDAHGNRQRAHYDGLPVEFVAEAICTLGTH---SPDR-----FV
MMAR_2117|M.marinum_M PGSFYELAADGARQRAHYDGLPVEFIAEAISTLGAQ---SQDG-----FH
MUL_1722|M.ulcerans_Agy99 PGSFYELAADGARQRAHYDGLPVEFIAEAISTLGAQ---SQDG-----FH
MLBr_00484|M.leprae_Br4923 PGSFYELDAESNRQRAHYDGLPVEFIAEAISTLGDQSLHDRDG-----FT
MAV_3471|M.avium_104 PGSFYELDADGNRQRAHYDGLPVEFIAAAISTLGSQITDSDTG-----FQ
Mvan_2578|M.vanbaalenii_PYR-1 PESFYHLATDGTRQRAHYDGLPVEFIAEAISTLGSD---VASG-----FR
TH_1879|M.thermoresistible__bu PKSFYRLGDDGSRQRAHFDGLPVDFVAEAVATLGWQIARTATGSPAGDFR
Mflv_2962|M.gilvum_PYR-GCK VS------------------------------------------------
MSMEG_5739|M.smegmatis_MC2_155 SYDVMNPHDDGISLDVFVDWLIR----AGHPIDRVDDYDDWVRRFETALT
MAB_3367|M.abscessus_ATCC_1997 SYDVMNPHDDGISVDTFVDWLME----DGHSIDIIDNYDEWLSRFETALR
Mb2621|M.bovis_AF2122/97 TYHVMNPYDDGIGLDEFVDWLNSPTSGSGCTIQRIADYGEWLQRFETSLR
Rv2590|M.tuberculosis_H37Rv TYHVMNPYDDGIGLDEFVDWLNSPTSGSGCTIQRIADYGEWLQRFETSLR
MMAR_2117|M.marinum_M TYHVMNPYDDGIGLDEFVDWLNE----SGCPIQRIADYGDWLQRFETALR
MUL_1722|M.ulcerans_Agy99 TYHVMNPYDDGIGLDEFVDWLNE----SGCPIQRIADYGDWLQRFETALR
MLBr_00484|M.leprae_Br4923 TYHVMNPHDDGIGMDEFVDWLID----AGCPIQRINDYDEWLRRFEISLR
MAV_3471|M.avium_104 TYHVMNPYDDGIGLDEYVDWLVD----AGYSIERIADYSEWLRRFETSLR
Mvan_2578|M.vanbaalenii_PYR-1 TYHVMNPHDDGIGLDEYVDWLID----AGHPIRRVGDYPTWLQRFTVAIT
TH_1879|M.thermoresistible__bu TYHVMNPHDDGIGIDEYVDWLIE----AGHPIERIDDFGEWLRRFEAGLH
Mflv_2962|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5739|M.smegmatis_MC2_155 ALPEKRRAQTVLPLLHAFRA------PQAPLRGAPEPTEVFHAAVRTAKV
MAB_3367|M.abscessus_ATCC_1997 GLPDEQRRASVLPLLDAYRI------PGNPRRAAATPNHVFRKAVQENNI
Mb2621|M.bovis_AF2122/97 ALPDRQRHTSLLPLLHNYRE------PAKPICGSIAPTDQFRAAVQEAKI
Rv2590|M.tuberculosis_H37Rv ALPDRQRHASLLPLLHNYRE------PAKPICGSIAPTDQFRAAVQEAKI
MMAR_2117|M.marinum_M ALPDRQRHSSLLPLLHNYRQ------PERPVRGSIAPTDRFRAAVQEAKI
MUL_1722|M.ulcerans_Agy99 ALPDRQRHSSLLPLLHNYRQ------PERPVRGSIAPTDRFRAAVQEAKI
MLBr_00484|M.leprae_Br4923 ALPERQRHSSLLPLLHNYQK------PEKPLHGSLAPTIRFRTAVQNANI
MAV_3471|M.avium_104 ALPDRQRQYSLLPLLHNYRT------PEKPINGSIAPTDVFRAAVQEAKI
Mvan_2578|M.vanbaalenii_PYR-1 ALPERQRQASLLPLLHNYQH------PETPIRGSIAPTDRFREAVQDAKI
TH_1879|M.thermoresistible__bu ALPERQRQHSVLQMLTLLRQQGGEPQPPEPRHGSDAPADRFEAAVKRAGI
Mflv_2962|M.gilvum_PYR-GCK -KAEAIRKFRILPVDFTEDT------------GELTPTLKVKRKVVAEKF
.: * :* : . * .. * .
MSMEG_5739|M.smegmatis_MC2_155 GP--GDIPHLDEALIDKYIRDLREFGLI
MAB_3367|M.abscessus_ATCC_1997 GGDGADIPQIDRALIAKYIADLRAHRLL
Mb2621|M.bovis_AF2122/97 GPD-KDIPHLTAAIIAKYISNLRLLGLL
Rv2590|M.tuberculosis_H37Rv GPD-KDIPHLTAAIIAKYISNLRLLGLL
MMAR_2117|M.marinum_M GPD-KDIPHVGAPIIVKYVSDLRLLGLL
MUL_1722|M.ulcerans_Agy99 GPD-KDIPHVGAPIIVKYVSDLRLLGLL
MLBr_00484|M.leprae_Br4923 GQD-KDIPHISPAIIAKYVSDLQLLGLV
MAV_3471|M.avium_104 GPD-KDIPHVSPPVIVKYITDLQLLGLL
Mvan_2578|M.vanbaalenii_PYR-1 GPD-KDIPHVTPQIVIKYVTDLQRLGLL
TH_1879|M.thermoresistible__bu NGG-QGIPHVTPEVIVRYVTDLRQLGLL
Mflv_2962|M.gilvum_PYR-GCK AAD---------------IEALYAKG--
: *