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MSTATHDERLDRRVHELIATDPQFAAAQPDPAITAALEQPGLRLPQIIRTVLDGYADRPALGQRVVEFVT DAKTGRTSAQLLPRFETITYGEVAQRVSALGRALSDDAVHPGDRVCVLGFNSVDYATIDMALGAIGAVSV PLQTSAAISSLQPIVAETEPTLIASSVNQLSDAVQLITGAEQAPTRLVVFDYHPQVDDQREAVQDAAARL SGTGVAVQTLAELLERGKDLPAVAEPPADEDSLALLIYTSGSTGAPKGAMYPQSNVGKMWRRGSKNWFGE SAASITLNFMPMSHVMGRSILYGTLGNGGTAYFAARSDLSTLLEDLELVRPTELNFVPRIWETLYGEFQR QVERRLSEAGDAGERRAVEAEVLAEQRQYLLGGRFTFAMTGSAPISPELRNWVESLLEMHLMDGYGSTEA GMVLFDGEIQRPPVVDYKLVDVPDLGYFSTDRPHPRGELLLRTENMFPGYYKRAETTAGVFDEDGYYRTG DVFAEIAPDRLVYVDRRNNVLKLAQGEFVTLAKLEAVFGNSPLIRQIYVYGNSAQPYLLAVVVPTEEALA SGDPETLKPKIADSLQQVAKEAGLQSYEVPRDFIIETTPFSLENGLLTGIRKLAWPKLKQHYGERLEQMY ADLAAGQADELAELRRNGAQAPVLQTVSRAAGAMLGSAASDLSPDAHFTDLGGDSLSALTFGNLLREIFD VDVPVGVIVSPANDLAAIASYIEAERQGSKRPTFASVHGRDATVVRAADLTLDKFLDADTLASAPNLPKP ATEVRTVLLTGATGFLGRYLALEWLERMDMVDGKVIALVRARSDEEARARLDKTFDSGDPKLLAHYQQLA ADHLEVIAGDKGEANLGLRQDVWQRLADTVDVIVDPAALVNHVLPYSELFGPNALGTAELIRLALTSKQK PYTYVSTIGVGDQIEPGKFVENADIRQMSATRAINDSYANGYGNSKWAGEVLLREAHDLCGLPVAVFRCD MILADTTYAGQLNLPDMFTRLMLSLVATGIAPGSFYELDADGNRQRAHYDGLPVEFIAAAISTLGSQITD SDTGFQTYHVMNPYDDGIGLDEYVDWLVDAGYSIERIADYSEWLRRFETSLRALPDRQRQYSLLPLLHNY RTPEKPINGSIAPTDVFRAAVQEAKIGPDKDIPHVSPPVIVKYITDLQLLGLL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3471 | - | - | 100% (1173) | putative acyl-CoA dehydrogenase |
| M. avium 104 | MAV_3239 | - | 0.0 | 40.81% (1115) | syringomycin synthetase |
| M. avium 104 | MAV_3243 | - | 0.0 | 50.19% (789) | linear gramicidin synthetase subunit B |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2621 | fadD9 | 0.0 | 69.87% (1175) | fatty-acid-CoA ligase |
| M. gilvum PYR-GCK | Mflv_2962 | - | 6e-38 | 27.13% (586) | AMP-dependent synthetase and ligase |
| M. tuberculosis H37Rv | Rv2590 | fadD9 | 0.0 | 69.96% (1175) | fatty-acid-CoA ligase |
| M. leprae Br4923 | MLBr_00484 | fadD9 | 0.0 | 76.62% (1176) | putative acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_2962 | - | 0.0 | 58.02% (1184) | fatty-acid-CoA ligase FadD |
| M. marinum M | MMAR_2117 | fadD9 | 0.0 | 72.57% (1185) | fatty-acid-CoA ligase FadD9 |
| M. smegmatis MC2 155 | MSMEG_2956 | - | 0.0 | 71.88% (1177) | NAD dependent epimerase/dehydratase family protein |
| M. thermoresistible (build 8) | TH_1879 | fadD9 | 1e-166 | 56.78% (546) | PROBABLE FATTY-ACID-CoA LIGASE FADD9 (FATTY-ACID-CoA |
| M. ulcerans Agy99 | MUL_1722 | - | 0.0 | 72.15% (1185) | fatty-acid-CoA ligase FadD9 |
| M. vanbaalenii PYR-1 | Mvan_2578 | - | 0.0 | 69.09% (1181) | thioester reductase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_3471|M.avium_104 --------------MSTATHDER-LDRRVHELIATDPQFAAAQPDPAITA
MLBr_00484|M.leprae_Br4923 MWRQQSISHRKESVMSTITKQEKQLARRVDDLTANDPQFAAAKPDPAVAA
Mb2621|M.bovis_AF2122/97 --------------MS--INDQR-LTRRVEDLYASDAQFAAASPNEAITQ
Rv2590|M.tuberculosis_H37Rv --------------MS--INDQR-LTRRVEDLYASDAQFAAASPNEAITQ
MMAR_2117|M.marinum_M --------------MSPITREER-LERRIQDLYANDPQFAAAKPATAITA
MUL_1722|M.ulcerans_Agy99 --------------MSPITREER-LERRIQDLYANDPQFAAAKPVTAITA
MSMEG_2956|M.smegmatis_MC2_155 --------------MTIETREDR-FNRRIDHLFETDPQFAAARPDEAISA
Mvan_2578|M.vanbaalenii_PYR-1 --------------MSTDTREDR-LARRIADLYATDPQFAAAAPDDAISH
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 -----------MTVTNETNPQQEQLSRRIESLRESDPQFRAAQPDPAVAE
Mflv_2962|M.gilvum_PYR-GCK ---------------------------MTAREFTVPAPFTVEERDNIVGA
MAV_3471|M.avium_104 ALEQPGLRLPQIIRTVLDGYADRPALGQRVVEFVTDAKTGRTSAQLLPRF
MLBr_00484|M.leprae_Br4923 ALAQPGLRLPQIIQTALDGYAERPALGQRVAEFTKDPKTGRTSMELLPSF
Mb2621|M.bovis_AF2122/97 AIDQPGVALPQLIRMVMEGYADRPALGQRALRFVTDPDSGRTMVELLPRF
Rv2590|M.tuberculosis_H37Rv AIDQPGVALPQLIRMVMEGYADRPALGQRALRFVTDPDSGRTMVELLPRF
MMAR_2117|M.marinum_M AIERPGLPLPQIIETVMTGYADRPALAQRSVEFVTDAGTGHTTLRLLPHF
MUL_1722|M.ulcerans_Agy99 AIERPGLPLPQIIETVMTGYADRPALAQRSVEFVTDAGTGHTTLRLLPHF
MSMEG_2956|M.smegmatis_MC2_155 AAADPELRLPAAVKQILAGYADRPALGKRAVEFVTD-EEGRTTAKLLPRF
Mvan_2578|M.vanbaalenii_PYR-1 AIDQPGTHLPVIVQTVLDGYAERPALGQRAVRFVTDPATGRTTTELLPRF
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 QVLRPGLHLSEAIAALMTGYAERPALGERARELVTD-QDGRTTLRLLPRF
Mflv_2962|M.gilvum_PYR-GCK VFTHERDDPDHVIFQRLVDG----------------------------KW
MAV_3471|M.avium_104 ETITYGEVAQRVSALGRALSDD---AVHPGDRVCVLGFNSVDYATIDMAL
MLBr_00484|M.leprae_Br4923 ETITYRQLGDRVGALARAWRHD---LLHAGYRVCVLGFNSVDYAIIDMAL
Mb2621|M.bovis_AF2122/97 ETITYRELWARAGTLATALSAEP--AIRPGDRVCVLGFNSVDYTTIDIAL
Rv2590|M.tuberculosis_H37Rv ETITYRELWARAGTLATALSAEP--AIRPGDRVCVLGFNSVDYTTIDIAL
MMAR_2117|M.marinum_M ETISYGELWDRISALADVLSTEQ--TVKPGDRVCLLGFNSVDYATIDMTL
MUL_1722|M.ulcerans_Agy99 ETISYGELWDRISALADVLSTEQ--TVKPSDRVCLLGFNSVDYATIDMTL
MSMEG_2956|M.smegmatis_MC2_155 DTITYRQLAGRIQAVTNAWHNH---PVNAGDRVAILGFTSVDYTTIDIAL
Mvan_2578|M.vanbaalenii_PYR-1 ETITYAELSRRIHAVTAALT-----DVHPGDRVAVLGFTSIDYTTVDMAL
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 DTTTYGELWSRTTSVAAAWHHDAAHPVKAGDLVATLGFTSIDYTVLDLAI
Mflv_2962|M.gilvum_PYR-GCK IDVTARQAAGQIRSAARGLIAEG---VQAGDRVALLSATRYEWPILDFAI
MAV_3471|M.avium_104 GAIGAVSVPLQTSAAISSLQPIVAETEPTLIASSVNQLSDAVQLITGAEQ
MLBr_00484|M.leprae_Br4923 GVIGAVAVPLQTSAAITQLQSIVTETEPSMIATSVNQLPDTVELIL-SGQ
Mb2621|M.bovis_AF2122/97 IRLGAVSVPLQTSAPVTGLRPIVTETEPTMIATSIDNLGDAVEV-LAGHA
Rv2590|M.tuberculosis_H37Rv IRLGAVSVPLQTSAPVTGLRPIVTETEPTMIATSIDNLGDAVEV-LAGHA
MMAR_2117|M.marinum_M ARLGAVAVPLQTSAAITQLQPIVAETQPTMIAASVDALADATELALSGQT
MUL_1722|M.ulcerans_Agy99 ARLGAVAVPLQTSAAITQLQPIVAETQPTMIAASVDALADATELALSGQT
MSMEG_2956|M.smegmatis_MC2_155 LELGAVSVPLQTSAPVAQLQPIVAETEPKVIASSVDFLADAVALVESGPA
Mvan_2578|M.vanbaalenii_PYR-1 AMLGAVAVPLQTSAPATTVRPIVAETEPVVIASSVDALTDAVGLALDAPT
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 MILGGVAVPLQTSAPASQWTTILAEAEPNTLAVSIELIGAAMESVRATPS
Mflv_2962|M.gilvum_PYR-GCK LSIGAVTVPIYETSSAEQVQFVLADSGAVAAIAETDAHAAHIEAQRDTLP
MAV_3471|M.avium_104 APTRLVVFDYHPQVDDQREAVQDAAARLSGTG--VAVQTLAELLERG---
MLBr_00484|M.leprae_Br4923 APAKLVVFDYHPEVDEQHDAVATARARLADSS--VVVESLTEVLGRG---
Mb2621|M.bovis_AF2122/97 P-ARLVVFDYHGKVDTHREAVEAARARLAGS---VTIDTLAELIER----
Rv2590|M.tuberculosis_H37Rv P-ARLVVFDYHGKVDTHREAVEAARARLAGS---VTIDTLAELIER----
MMAR_2117|M.marinum_M A-TRVLVFDHHRQVDAHRAAVESARERLAGS---AVVETLAEAIARGDVP
MUL_1722|M.ulcerans_Agy99 A-TRVLVFDHHRQVDAHRAAVESARERLAGS---AVVETLAEAIARGDVP
MSMEG_2956|M.smegmatis_MC2_155 P-SRLVVFDYSHEVDDQREAFEAAKGKLAGTG--VVVETITDALDRG---
Mvan_2578|M.vanbaalenii_PYR-1 V-TRLVVFDHRAGVDDHRDALISASDRLRAANSPIEVETITDIVARG---
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 I-KQVVVFDYTPEVDDQREAFEAASTQLAGTG--IAIETLDAVIARG---
Mflv_2962|M.gilvum_PYR-GCK ALRRIYVIDGSVPALDELAEAGASVD------------------------
MAV_3471|M.avium_104 KDLPAVAEPPADE--DSLALLIYTSGSTGAPKGAMYPQSNVGKMWRRGSK
MLBr_00484|M.leprae_Br4923 KTLPATPIPVADDSADPLALLIYTSGSTGAPKGAMYLQSNVGKMWRRSDG
Mb2621|M.bovis_AF2122/97 -GRALPATPIADSADDALALLIYTSGSTGAPKGAMYRESQVMSFWRKSSG
Rv2590|M.tuberculosis_H37Rv -GRALPATPIADSADDALALLIYTSGSTGAPKGAMYRESQVMSFWRKSSG
MMAR_2117|M.marinum_M RGASAGSAPGTDVSDDSLALLIYTSGSTGAPKGAMYPRRNVATFWRKRT-
MUL_1722|M.ulcerans_Agy99 RGASAGSAPGTDVSDDSLALLIYTSGSTGAPKGAMYPRRNVATFWRKRT-
MSMEG_2956|M.smegmatis_MC2_155 -RSLADAPLYVPDEADPLTLLIYTSGSTGTPKGAMYPESKTATMWQAGSK
Mvan_2578|M.vanbaalenii_PYR-1 -SKLPVRAQFS-ADGDALSLLIYTSGSTGAPKGAMYPQHLVANSWRRLAR
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 AALPAAPLYAPSAGDDPLALLIYTSGSTGAPKGAMHSENIVRRWWIREDV
Mflv_2962|M.gilvum_PYR-GCK --AAAVDERVASIRSTDAATLIYTSGTTGRPKGCQLTHSNLLYEIRGAKA
MAV_3471|M.avium_104 NWFGE---SAASITLNFMPMSHVMGRSILYGTLGNGGTAYFAARSDLSTL
MLBr_00484|M.leprae_Br4923 NWFGP---TAASITLNFMPMSHVMGRGILYGTLGNGGTAYFAARSDLSTL
Mb2621|M.bovis_AF2122/97 WFEPS---GYPSITLNFMPMSHVGGRQVLYGTLSNGGTAYYVAKSDLSTL
Rv2590|M.tuberculosis_H37Rv WFEPS---GYPSITLNFMPMSHVGGRQVLYGTLSNGGTAYFVAKSDLSTL
MMAR_2117|M.marinum_M WFEGG---YEPSITLNFMPMSHVMGRQILYGTLCNGGTAYFVAKSDLSTL
MUL_1722|M.ulcerans_Agy99 WFEGG---YEPSITLNFMPMSHVMGRQILYGTLCNGGTAYFVVKSDLSTL
MSMEG_2956|M.smegmatis_MC2_155 ARWDETLGVMPSITLNFMPMSHVMGRGILCSTLASGGTAYFAARSDLSTF
Mvan_2578|M.vanbaalenii_PYR-1 SFWGD-LGVFPAITLNFMPMSHVMGRGLLYGTLDAGGTAYFAARSDLSTF
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 MAGTEN---LPMIGLNFMPMSHIMGRGTLTSTLSTGGTGYFAASSDMSTL
Mflv_2962|M.gilvum_PYR-GCK CFPEH--LAKGEKLLVFLPLAHVLARALTIGAFSNG--VTLGFTSDIKNL
MAV_3471|M.avium_104 LEDLELVRPTELNFVPRIWETLYGEFQRQVERRLSEAGDAGERRAVEAEV
MLBr_00484|M.leprae_Br4923 LEDLKLVRPTELNFVPRIWETLYDESKRAVDRRLANSGSA-DRAAIKAEV
Mb2621|M.bovis_AF2122/97 FEDLALVRPTELCFVPRIWDMVFAEFHSEVDRRLVD---GADRAALEAQV
Rv2590|M.tuberculosis_H37Rv FEDLALVRPTELCFVPRIWDMVFAEFHSEVDRRLVD---GADRAALEAQV
MMAR_2117|M.marinum_M FEDLALVRPTELTFVPRVWDMVFDEFQSEVDRRLVD---GADRVALEAQV
MUL_1722|M.ulcerans_Agy99 FEDLALVRPTELTFVPRVWDMVFDEFQSEVDRRLVD---GADRVALEAQV
MSMEG_2956|M.smegmatis_MC2_155 LEDLALVRPTQLNFVPRIWDMLFQEYQSRLDNRRAE----GSEDRAEAAV
Mvan_2578|M.vanbaalenii_PYR-1 LEDLALVRPTQLSFVPRIWDTIHAEVSQELERRPSD----ATE------V
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 FEDMELIRPTALALVPRVCDMVFQRFQTEVDRRLASS-DTASAEAVAAEV
Mflv_2962|M.gilvum_PYR-GCK VPMFAVFQPTLVVSVPRVFEKVYN--------------------------
MAV_3471|M.avium_104 LAEQRQYLLGGRFTFAMTGSAPISPELRNWVESLL-EMHLMDGYGSTEAG
MLBr_00484|M.leprae_Br4923 MDEQRQSLLGGRYIAAMTGSAPTSPELKHGVESLL-EMHLLEGYGSTEAG
Mb2621|M.bovis_AF2122/97 KAELRENVLGGRFVMALTGSAPISAEMTAWVESLLADVHLVEGYGSTEAG
Rv2590|M.tuberculosis_H37Rv KAELRENVLGGRFVMALTGSAPISAEMTAWVESLLADVHLVEGYGSTEAG
MMAR_2117|M.marinum_M KAEIRNDVLGGRYTSALTGSAPISDEMKAWVEELL-DMHLVEGYGSTEAG
MUL_1722|M.ulcerans_Agy99 KAEIRNDVLGGRYTSALTGSAPISDEMKAWVEELL-DMHLVEGYGSTEAG
MSMEG_2956|M.smegmatis_MC2_155 LEEVRTQLLGGRFVSALTGSAPISAEMKSWVEDLL-DMHLLEGYGSTEAG
Mvan_2578|M.vanbaalenii_PYR-1 IADLRRSLLGGRYVTAMTGSAPLSPEMRAFVENLL-DVHLIDGYGSTEAG
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 KADIRDNLFGGRVSAVMVGSAPLSEELGEFIESCF-ELNLTDGYGSTEAG
Mflv_2962|M.gilvum_PYR-GCK --------------------------------------------------
MAV_3471|M.avium_104 MVLFDGEIQRPPVVDYKLVDVPDLGYFSTDRPHPRGELLLRTENMFPGYY
MLBr_00484|M.leprae_Br4923 MVLFDGEVQRPPVIDYKLVDVPDLGYFSTDQPYPRGELLLKTQNMFPGYY
Mb2621|M.bovis_AF2122/97 MVLNDGMVRRPAVIDYKLVDVPELGYFGTDQPYPRGELLVKTQTMFPGYY
Rv2590|M.tuberculosis_H37Rv MVLNDGMVRRPAVIDYKLVDVPELGYFGTDQPYPRGELLVKTQTMFPGYY
MMAR_2117|M.marinum_M MILIDGAIRRPAVLDYKLVDVPDLGYFLTDRPHPRGELLVKTDSLFPGYY
MUL_1722|M.ulcerans_Agy99 MILIDGAIRRPAVLDYKLVDVPDLGYFLTDRPHPRGELLVKTDSLFPGYY
MSMEG_2956|M.smegmatis_MC2_155 AVFIDGQIQRPPVIDYKLVDVPDLGYFATDRPYPRGELLVKSEQMFPGYY
Mvan_2578|M.vanbaalenii_PYR-1 AVFVDGRVQRPPVIDYKLVDVADLGYFSTDRPHPRGELLVKSETLFPGYY
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 MVFRDGIVQRPPVIDYKLVDVPELGYFSTDKPHPRGELLLKTDGMFLGYY
Mflv_2962|M.gilvum_PYR-GCK --------------------------------------------------
MAV_3471|M.avium_104 KRAETTAGVFDEDGYYRTGDVFAEIAPDRLVYVDRRNNVLKLAQGEFVTL
MLBr_00484|M.leprae_Br4923 KRPEVTATVFDSDGYYQTGDIVAEVGPDRLVYVDRRNNVLKLAQGQFVTV
Mb2621|M.bovis_AF2122/97 QRPDVTAEVFDPDGFYRTGDIMAKVGPDQFVYLDRRNNVLKLSQGEFIAV
Rv2590|M.tuberculosis_H37Rv QRPDVTAEVFDPDGFYRTGDIMAKVGPDQFVYLDRRNNVLKLSQGEFIAV
MMAR_2117|M.marinum_M QRAEVTADVFDADGFYRTGDIMAEVGPEQFVYLDRRNNVLKLSQGEFVTV
MUL_1722|M.ulcerans_Agy99 QRAEVTADVFDADGFYRTGDIMAEVGPEQFVYLDRRNNVLKLSQGEFVTV
MSMEG_2956|M.smegmatis_MC2_155 KRPEITAEMFDEDGYYRTGDIVAELGPDHLEYLDRRNNVLKLSQGEFVTV
Mvan_2578|M.vanbaalenii_PYR-1 KRPDVTAEMFDEDGYYRTGDIVAETGADQLTYLDRRNNVLKLSQGEFVTV
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 KRPEVTAGVFDADGFYMTGDIVAELAHDNIEIIDRRNNVLKLSQGEFVAV
Mflv_2962|M.gilvum_PYR-GCK -----------------TAELNAETGGKGKIFTAAANTAIEYS-------
MAV_3471|M.avium_104 AKLEAVFGNSPLIRQIYVYGNSAQPYLLAVVVPTEEALASGD--PETLKP
MLBr_00484|M.leprae_Br4923 AKLEAAFSNSPLVRQIYIYGNSAHPYLLAVVVPTEDALATND--IEVLKP
Mb2621|M.bovis_AF2122/97 SKLEAVFGDSPLVRQIFIYGNSARAYPLAVVVPSGDALSRHG--IENLKP
Rv2590|M.tuberculosis_H37Rv SKLEAVFGDSPLVRQIFIYGNSARAYPLAVVVPSGDALSRHG--IENLKP
MMAR_2117|M.marinum_M SKLEAVFGDSPLVRQIYIYGNSARAYLLAVIVPTQEALDAVP--VEELKA
MUL_1722|M.ulcerans_Agy99 SKLEAVFGDSPLVRQIYIYGNSARAYLLAVIVPTQEALDAVP--VEELKA
MSMEG_2956|M.smegmatis_MC2_155 SKLEAVFGDSPLVRQIYVYGNSARSYLLAVVVPTEEALSRWD--GDELKS
Mvan_2578|M.vanbaalenii_PYR-1 SRLEAVFGNSPLVRQIYVYGNSARPYLLAVVVPTEAALA-----GADAKA
TH_1879|M.thermoresistible__bu --------------------------------------------------
MAB_2962|M.abscessus_ATCC_1997 ATLEAEYANSPVVHQIYVYGSSERSYLLAVVVPTPEAVAAAKGDAAALKT
Mflv_2962|M.gilvum_PYR-GCK --------------------------------------------------
MAV_3471|M.avium_104 KIADSLQQVAKEAG-LQSYEVPRDFIIETTPFSLENGLLTGIRKLAWPKL
MLBr_00484|M.leprae_Br4923 LIIDSLQKVAKEAD-LQSYEVPRDLIVETTPFSLENGLLTGIRKLAWPKL
Mb2621|M.bovis_AF2122/97 VISESLQEVARAAG-LQSYEIPRDFIIETTPFTLENGLLTGIRKLARPQL
Rv2590|M.tuberculosis_H37Rv VISESLQEVARAAG-LQSYEIPRDFIIETTPFTLENGLLTGIRKLARPQL
MMAR_2117|M.marinum_M RLGDSLQEVAKAAG-LQSYEIPRDFIIETTPWTLENGLLTGIRKLARPQL
MUL_1722|M.ulcerans_Agy99 RLGDSLQEVAKAAG-LQSYEIPRDFIIETTPWTLQNGLLTGIRKLARPQL
MSMEG_2956|M.smegmatis_MC2_155 RISDSLQDAARAAG-LQSYEIPRDFLVETTPFTLENGLLTGIRKLARPKL
Mvan_2578|M.vanbaalenii_PYR-1 AVAESLQDVAKATG-LQSYEIPRDFLLETTPFTLENGLLTGIRKLARPRL
TH_1879|M.thermoresistible__bu -VGLSXQARARLADRLPAYMVPAAVVVLDRIPLTVNGKLD-RRALPAPEY
MAB_2962|M.abscessus_ATCC_1997 TIADSLQDIAKEIQ-LQSYEVPRDFIIEPQPFTQGNGLLTGIAKLARPNL
Mflv_2962|M.gilvum_PYR-GCK --------------------------------------------------
MAV_3471|M.avium_104 KQHYGERLEQMYADLAAGQADELAELRRNGAQAPVLQTVSRAAGAMLGSA
MLBr_00484|M.leprae_Br4923 KQHYGARLEQLYADLVEGQANALHVLKQSVANAPVLQTVSRAVGTILGVA
Mb2621|M.bovis_AF2122/97 KKFYGERLERLYTELADSQSNELRELRQSGPDAPVLPTLCRAAAALLGST
Rv2590|M.tuberculosis_H37Rv KKFYGERLERLYTELADSQSNELRELRQSGPDAPVLPTLCRAAAALLGST
MMAR_2117|M.marinum_M KKHYGELLEQIYTDLAHGQADELRSLRQSGADAPVLVTVCRAAAALLGGS
MUL_1722|M.ulcerans_Agy99 KKHYGELLEQIYTDLAHGQADELRSLRQSGADAPVLVTVCRAAAALLGGS
MSMEG_2956|M.smegmatis_MC2_155 KAHYGERLEQLYTDLAEGQANELRELRRNGADRPVVETVSRAAVALLGAS
Mvan_2578|M.vanbaalenii_PYR-1 RERYGEQLEALYTMLSEEQADELRELRRSGGERPALETVGRAAGALLGTT
TH_1879|M.thermoresistible__bu QRAD----------------------RYRAPETAVEKTLTEIFAHVLG--
MAB_2962|M.abscessus_ATCC_1997 KAHYGPRLEQMYAEIAEQQAAELRALHGVDPDKPALETVLKAAQALLGVS
Mflv_2962|M.gilvum_PYR-GCK -----------------------KALDSGGPGLVLKLKHALFDKLVYGKL
. : *
MAV_3471|M.avium_104 ASDLSPDAHFTDLGGDSLSALTFGNLLREIFDVDVPVGVIVSPANDLAAI
MLBr_00484|M.leprae_Br4923 TTDLPSNAHFTDLGGDSLSALTFGSLLRELFDIDVPVGVIVSPVNNLVAI
Mb2621|M.bovis_AF2122/97 AADVRPDAHFADLGGDSLSALSLANLLHEIFGVDVPVGVIVSPASDLRAL
Rv2590|M.tuberculosis_H37Rv AADVRPDAHFADLGGDSLSALSLANLLHEIFGVDVPVGVIVSPASDLRAL
MMAR_2117|M.marinum_M ASDVQPDAHFTDLGGDSLSALSFTNLLHEIFDIEVPVGVIVSPANDLQAL
MUL_1722|M.ulcerans_Agy99 ASDVQPDAHFTDLGGDSLSALSFTNLLHEIFDIDVPVGVIVSPANDLQAL
MSMEG_2956|M.smegmatis_MC2_155 VTDLRSDAHFTDLGGDSLSALSFSNLLHEIFDVDVPVGVIVSPATDLAGV
Mvan_2578|M.vanbaalenii_PYR-1 AGELEPSAHFTDLGGDSLSALTFANLLRDIFDVDVPVGVIVSPATDLQAL
TH_1879|M.thermoresistible__bu LERVGVDDSFFDLGGDSISAMRAVAAINTALDTDVAVRTLFEAP-TVRRL
MAB_2962|M.abscessus_ATCC_1997 SAELAADAHFTDLGGDSLSALSFSDLLRDIFAVEVPVGVIVSAANDLSGV
Mflv_2962|M.gilvum_PYR-GCK RAALGGRCHAAISGGAPLGAR--------LGHFYRGVGLSIYEGYGLTET
: ** .:.* * . :
MAV_3471|M.avium_104 ASYIE-----AER-QGSKRPTFASVHGRD---ATVVRAADLTLDKFLDAD
MLBr_00484|M.leprae_Br4923 ADYIE-----RER-QGTKRPTFIAIHGRD---AGKVHASDLTLDKFIDVS
Mb2621|M.bovis_AF2122/97 ADHIE-----AAR-TGVRRPSFASIHGRS---ATEVHASDLTLDKFIDAA
Rv2590|M.tuberculosis_H37Rv ADHIE-----AAR-TGVRRPSFASIHGRS---ATEVHASDLTLDKFIDAA
MMAR_2117|M.marinum_M ADYVE-----AARKPGSSRPTFASVHGASNGQVTEVHAGDLSLDKFIDAA
MUL_1722|M.ulcerans_Agy99 ADYVE-----AARKPGSSRPTFASVHGASNEQVTEVHAGDLSLDKFIDAA
MSMEG_2956|M.smegmatis_MC2_155 AAYIE-----GELR-GSKRPTYASVHG---RDATEVRARDLALGKFIDAK
Mvan_2578|M.vanbaalenii_PYR-1 ADYVE-----SARRHGSVRPTFESVHGHSGRPGTEVHARDLTLDEFVDAA
TH_1879|M.thermoresistible__bu SRQLEGGADTAPQGADLGAVTYESVHGAT---ATEVRAADLTLDRFIDAA
MAB_2962|M.abscessus_ATCC_1997 AKFVD-----EQRYSGGTRPTAETVHGAG---HTEIRAADLTLDKFIDEA
Mflv_2962|M.gilvum_PYR-GCK SAAIT-----------------------------VNRVGDLRVG-----S
: : :. ** :.
MAV_3471|M.avium_104 TLASAPNLPKPATEVRTVLLTGATGFLGRYLALEWLERMDMVDGKVIALV
MLBr_00484|M.leprae_Br4923 TLTAAPVLAQPGTEVRTVLLTGATGFLGRYLALKWLERMDLVEGKVIALV
Mb2621|M.bovis_AF2122/97 TLAAAPNLPAPSAQVRTVLLTGATGFLGRYLALEWLDRMDLVNGKLICLV
Rv2590|M.tuberculosis_H37Rv TLAAAPNLPAPSAQVRTVLLTGATGFLGRYLALEWLDRMDLVNGKLICLV
MMAR_2117|M.marinum_M TLAEAPRLPAANTQVRTVLLTGATGFLGRYLALEWLERMDLVDGKLICLV
MUL_1722|M.ulcerans_Agy99 TLAEAPRLPAANTQVRTVLLTGATGFLGRYLALEWLERMDLVDGKLICLV
MSMEG_2956|M.smegmatis_MC2_155 TLSAAPGLPRSGTEIRTVLLTGATGFLGRYLALEWLERMDLVDGKVICLV
Mvan_2578|M.vanbaalenii_PYR-1 TLAHAPTLPGPRAEVRTVLLTGATGFLGRYLALEWLERMALVGGKLICLV
TH_1879|M.thermoresistible__bu TLRTAADLPRPTGQVQTVLLTGATGFLGRYLLLEWLRRLRRVDDTVICLV
MAB_2962|M.abscessus_ATCC_1997 TLHAAPSLPKAVGIPHTVLLTGSNGYLGHYLALEWLERLDKTEGKLIAIV
Mflv_2962|M.gilvum_PYR-GCK VGKLVPGNSMRLGEDGELLVRGGVVFNG-YWGNEEETRAVFTDGWFHTGD
. .. . :*: *. : * * : * . . .
MAV_3471|M.avium_104 RARSDEEARARLDKTFDSGDPKLLAHYQQLAADHLEVIAGDKGEANLGLR
MLBr_00484|M.leprae_Br4923 RAKSNEDARARLDKTFDSGDPKLLAHYQELATDHLEVIAGDKGEVDLELD
Mb2621|M.bovis_AF2122/97 RARSDEEAQARLDATFDSGDPYLVRHYRELGAGRLEVLAGDKGEADLGLD
Rv2590|M.tuberculosis_H37Rv RARSDEEAQARLDATFDSGDPYLVRHYRELGAGRLEVLAGDKGEADLGLD
MMAR_2117|M.marinum_M RAKSDTEARARLDKTFDSGDPELLAHYRALAGDHLEVLAGDKGEADLGLD
MUL_1722|M.ulcerans_Agy99 RAKSDTEARARLEKTFDSGAPELLAHYRALAGDHLEVLAGDKGEADLGLD
MSMEG_2956|M.smegmatis_MC2_155 RARSDDEARARLDATFDTGDATLLEHYRALAADHLEVIAGDKGEADLGLD
Mvan_2578|M.vanbaalenii_PYR-1 RAKDDAAARVRLDSTFDSGDPELLRHYRRLAADHLEVIAGDKADADLGLD
TH_1879|M.thermoresistible__bu RGRSDADARQRLEAVFDT-DPALRRHFRELAAERLQVIAGDKGQPNLGLD
MAB_2962|M.abscessus_ATCC_1997 RGKNAEAAYRRLEEAFDTGDTQLLAHFRSLADKHLEVLAGDIGDPNLGLD
Mflv_2962|M.gilvum_PYR-GCK LGAIDDDG------------------FLTIVGRKKEIIVTAGGKN-----
. . : : : :::. ..
MAV_3471|M.avium_104 QDVWQRLADTVDVIVDPAALVNHVLPYSELFGPNALGTAELIRLALTSKQ
MLBr_00484|M.leprae_Br4923 RQTWRRLADTVDLIVDPAALVNHVLPYSELFGPNTLGTAELIRIALTSKQ
Mb2621|M.bovis_AF2122/97 RVTWQRLADTVDLIVDPAALVNHVLPYSQLFGPNAAGTAELLRLALTGKR
Rv2590|M.tuberculosis_H37Rv RVTWQRLADTVDLIVDPAALVNHVLPYSQLFGPNAAGTAELLRLALTGKR
MMAR_2117|M.marinum_M RQTWQRLADTVDLIVDPAALVNHVLPYSQLFGPNALGTAELLRLALTSKI
MUL_1722|M.ulcerans_Agy99 RQTWQRLADTVDLIVDPAALVNHVLPYSQLFGPNALGTAELLRLALTSKI
MSMEG_2956|M.smegmatis_MC2_155 HDTWQRLADTVDLIVDPAALVNHVLPYSQMFGPNALGTAELIRIALTTTI
Mvan_2578|M.vanbaalenii_PYR-1 ARTWQRLADTVDLIVDPAALVNHVLPYRQLFAPNVLGTAELLRIALTTRM
TH_1879|M.thermoresistible__bu VQTWRRLAERVDLIVDSAAFVNSVLPYRELFGPNVVGTAELIRFALTAKL
MAB_2962|M.abscessus_ATCC_1997 ADTWQRLADTVDVIVHPAALVNHVLPYSQLFGPNVVGTAEIIKLAITTKI
Mflv_2962|M.gilvum_PYR-GCK --------------VAPAQLEDRLRAHPLISQAMAVGDQQPFIAALIT--
* .* : : : .: : . . * : : *:
MAV_3471|M.avium_104 KPYTYVSTIGVGDQIEPGKFVENADIRQMSATRAINDSYANGYGNSKWAG
MLBr_00484|M.leprae_Br4923 KPYIYVSTIGVGNQIEPAKFTEDSDIRVISPTRNINNNYANGYGNSKWAG
Mb2621|M.bovis_AF2122/97 KPYIYTSTIAVGEQIPPEAFTEDADIRAISPTRRIDDSYANGYANSKWAG
Rv2590|M.tuberculosis_H37Rv KPYIYTSTIAVGEQIPPEAFTEDADIRAISPTRRIDDSYANGYANSKWAG
MMAR_2117|M.marinum_M KPYSYTSTIGVADQIPPSAFTEDADIRVISATRAVDDSYANGYSNSKWAG
MUL_1722|M.ulcerans_Agy99 KPYSYTSTIGVADQIPPSAFTEDADIRVISATRAVDDSYANGYSNSKWAG
MSMEG_2956|M.smegmatis_MC2_155 KPYVYVSTIGVGQGISPEAFVEDADIREISATRRVDDSYANGYGNSKWAG
Mvan_2578|M.vanbaalenii_PYR-1 KPFVYVSTIGVGAGIEPARFTEDADIRQISATRRIDDSYANGYGNSKWAG
TH_1879|M.thermoresistible__bu KPYNFVSTSDIGRQIEPDLFTEDADIRTISPTRTVDASYANGYGNSKWAG
MAB_2962|M.abscessus_ATCC_1997 KPVTYLSTVAVAAYVDPTTFDEESDIRLISAVRPVDELYANGYGNSKWAG
Mflv_2962|M.gilvum_PYR-GCK --------------VDTEAFPGWKERHHKASDASVADLADD---------
: . * : : :. : :
MAV_3471|M.avium_104 EVLLREAHDLCGLPVAVFRCDMILADTTYAGQLNLPDMFTRLMLSLVATG
MLBr_00484|M.leprae_Br4923 EVLLREAHDLCGLPVTVFRCDMILADTSYAGQLNVPDMFTRMMLSLAATG
Mb2621|M.bovis_AF2122/97 EVLLREAHEQCGLPVTVFRCDMILADTSYTGQLNLPDMFTRLMLSLAATG
Rv2590|M.tuberculosis_H37Rv EVLLREAHEQCGLPVTVFRCDMILADTSYTGQLNLPDMFTRLMLSLAATG
MMAR_2117|M.marinum_M EVLLREAHDLCGLPVAVFRCDMILADTTWAGQLNVPDMFTRMILSLAATG
MUL_1722|M.ulcerans_Agy99 EVLLREAHVLCGLPVAVFRCDMILADTTWAGQLNVPDMFTRMILSLAATG
MSMEG_2956|M.smegmatis_MC2_155 EVLLREAHDWCGLPVSVFRCDMILADTTYSGQLNLPDMFTRLMLSLVATG
Mvan_2578|M.vanbaalenii_PYR-1 EVLLREAHDLCGLPVSVFRCDMILADTTYAGQLNLPDMFTRLIFSLVATG
TH_1879|M.thermoresistible__bu EVLLREAHDLCGLPVAVFRSGMILVDPTYAGQLNVTDTVSRMVLSIVATG
MAB_2962|M.abscessus_ATCC_1997 EVLLREAHDLCGLPVAVFRSDMILAHSRYTGQLNVPDQFTRLILSLIATG
Mflv_2962|M.gilvum_PYR-GCK -----------------------------------PDLLAEIELAVKDAN
.* .:.: ::: :.
MAV_3471|M.avium_104 IAPGSFYELDADGNRQRAHYDGLPVEFIAAAISTLGSQITDSDTG-----
MLBr_00484|M.leprae_Br4923 IAPGSFYELDAESNRQRAHYDGLPVEFIAEAISTLGDQSLHDRDG-----
Mb2621|M.bovis_AF2122/97 IAPGSFYELDAHGNRQRAHYDGLPVEFVAEAICTLGTH---SPDR-----
Rv2590|M.tuberculosis_H37Rv IAPGSFYELDAHGNRQRAHYDGLPVEFVAEAICTLGTH---SPDR-----
MMAR_2117|M.marinum_M IAPGSFYELAADGARQRAHYDGLPVEFIAEAISTLGAQ---SQDG-----
MUL_1722|M.ulcerans_Agy99 IAPGSFYELAADGARQRAHYDGLPVEFIAEAISTLGAQ---SQDG-----
MSMEG_2956|M.smegmatis_MC2_155 IAPGSFYELDADGNRQRAHYDGLPVEFIAEAISTIGSQ---VTDG-----
Mvan_2578|M.vanbaalenii_PYR-1 VAPESFYHLATDGTRQRAHYDGLPVEFIAEAISTLGSD---VASG-----
TH_1879|M.thermoresistible__bu VAPKSFYRLGDDGSRQRAHFDGLPVDFVAEAVATLGWQIARTATGSPAGD
MAB_2962|M.abscessus_ATCC_1997 IAPGSFYQAHATGERPLAHYDGLPGDFTAEAITTLGTQ---VVDS-----
Mflv_2962|M.gilvum_PYR-GCK QAVS----------------------------------------------
*
MAV_3471|M.avium_104 FQTYHVMNPYDDGIGLDEYVDWLVD----AGYSIERIADYSEWLRRFETS
MLBr_00484|M.leprae_Br4923 FTTYHVMNPHDDGIGMDEFVDWLID----AGCPIQRINDYDEWLRRFEIS
Mb2621|M.bovis_AF2122/97 FVTYHVMNPYDDGIGLDEFVDWLNSPTSGSGCTIQRIADYGEWLQRFETS
Rv2590|M.tuberculosis_H37Rv FVTYHVMNPYDDGIGLDEFVDWLNSPTSGSGCTIQRIADYGEWLQRFETS
MMAR_2117|M.marinum_M FHTYHVMNPYDDGIGLDEFVDWLNE----SGCPIQRIADYGDWLQRFETA
MUL_1722|M.ulcerans_Agy99 FHTYHVMNPYDDGIGLDEFVDWLNE----SGCPIQRIADYGDWLQRFETA
MSMEG_2956|M.smegmatis_MC2_155 FETFHVMNPYDDGIGLDEYVDWLIE----AGYPVHRVDDYATWLSRFETA
Mvan_2578|M.vanbaalenii_PYR-1 FRTYHVMNPHDDGIGLDEYVDWLID----AGHPIRRVGDYPTWLQRFTVA
TH_1879|M.thermoresistible__bu FRTYHVMNPHDDGIGIDEYVDWLIE----AGHPIERIDDFGEWLRRFEAG
MAB_2962|M.abscessus_ATCC_1997 YETYDCVNPHADGVSLDNFVDWLIE----AGYPIARIDNYTEWFTRFDTA
Mflv_2962|M.gilvum_PYR-GCK --------------------------------------------------
MAV_3471|M.avium_104 LRALPDRQRQYSLLPLLHNYRT------PEKPINGSIAPTDVFRAAVQEA
MLBr_00484|M.leprae_Br4923 LRALPERQRHSSLLPLLHNYQK------PEKPLHGSLAPTIRFRTAVQNA
Mb2621|M.bovis_AF2122/97 LRALPDRQRHTSLLPLLHNYRE------PAKPICGSIAPTDQFRAAVQEA
Rv2590|M.tuberculosis_H37Rv LRALPDRQRHASLLPLLHNYRE------PAKPICGSIAPTDQFRAAVQEA
MMAR_2117|M.marinum_M LRALPDRQRHSSLLPLLHNYRQ------PERPVRGSIAPTDRFRAAVQEA
MUL_1722|M.ulcerans_Agy99 LRALPDRQRHSSLLPLLHNYRQ------PERPVRGSIAPTDRFRAAVQEA
MSMEG_2956|M.smegmatis_MC2_155 LRALPERQRQASLLPLLHNYQQ------PSPPVCGAMAPTDRFRAAVQDA
Mvan_2578|M.vanbaalenii_PYR-1 ITALPERQRQASLLPLLHNYQH------PETPIRGSIAPTDRFREAVQDA
TH_1879|M.thermoresistible__bu LHALPERQRQHSVLQMLTLLRQQGGEPQPPEPRHGSDAPADRFEAAVKRA
MAB_2962|M.abscessus_ATCC_1997 IRSLPEKQKQHSLLPLLHAFEQ------PSAAENHGVVPAKRFQHAVQAA
Mflv_2962|M.gilvum_PYR-GCK ---KAEAIRKFRILPVDFTEDT------------GELTPTLKVKRKVVAE
.: :: :* : .*: .. *
MAV_3471|M.avium_104 KIGPD-----KDIPHVSPPVIVKYITDLQLLGLL
MLBr_00484|M.leprae_Br4923 NIGQD-----KDIPHISPAIIAKYVSDLQLLGLV
Mb2621|M.bovis_AF2122/97 KIGPD-----KDIPHLTAAIIAKYISNLRLLGLL
Rv2590|M.tuberculosis_H37Rv KIGPD-----KDIPHLTAAIIAKYISNLRLLGLL
MMAR_2117|M.marinum_M KIGPD-----KDIPHVGAPIIVKYVSDLRLLGLL
MUL_1722|M.ulcerans_Agy99 KIGPD-----KDIPHVGAPIIVKYVSDLRLLGLL
MSMEG_2956|M.smegmatis_MC2_155 KIGPD-----KDIPHVTADVIVKYISNLQMLGLL
Mvan_2578|M.vanbaalenii_PYR-1 KIGPD-----KDIPHVTPQIVIKYVTDLQRLGLL
TH_1879|M.thermoresistible__bu GINGG-----QGIPHVTPEVIVRYVTDLRQLGLL
MAB_2962|M.abscessus_ATCC_1997 GIGPAGQDGTTDIPHLSRRLIVKYAKDLEQLGLL
Mflv_2962|M.gilvum_PYR-GCK KFAAD--------------IEALYAKG-------
: : * ..