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RPHRRSALLQQLVAVAPSQQAVLDELRRAILDGGVPPGTPIPLAEVAEVFGVSQIPVREALKTLIGEGLV AHRRNAGYTVALLTAQELREMYIVRETLESASLMAAVANATEADRDAAIAANAVLEQAIADDDAATYHRE SRQFHAALTRPSRMHRLLHMLEAAWNVTEPVQSMVHVRADERVQLHADHREMLDAFLMRDAERLVAASEA HAARLNAVIAVLPTGTGLLA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5731 | - | - | 100% (231) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_2453 | - | 4e-23 | 31.28% (211) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_3400 | - | 3e-20 | 29.19% (209) | glutamyl-tRNA(Gln) amidotransferase subunit A |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0170c | - | 1e-15 | 32.26% (186) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0715 | - | 2e-11 | 27.17% (184) | regulatory protein GntR, HTH |
| M. tuberculosis H37Rv | Rv0165c | - | 8e-15 | 35.00% (140) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2933c | - | 3e-57 | 52.04% (221) | GntR family transcriptional regulator |
| M. marinum M | MMAR_0408 | - | 9e-13 | 28.23% (209) | GntR family transcriptional regulator |
| M. avium 104 | MAV_5020 | - | 1e-15 | 30.49% (223) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_0156 | - | 2e-16 | 31.35% (185) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_1833 | - | 5e-12 | 27.65% (217) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0931 | - | 3e-85 | 70.69% (232) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5731|M.smegmatis_MC2_155 -----------------------------------------MRPHRRSAL
Mvan_0931|M.vanbaalenii_PYR-1 -----------------------------------------MPHRRHSVL
MAB_2933c|M.abscessus_ATCC_199 ----------------------------------------MSRTFRYRRL
Mflv_0715|M.gilvum_PYR-GCK -----------------------------------MRAADAMNAPARART
TH_0156|M.thermoresistible__bu -----------------------------------------MNAPITSRL
Mb0170c|M.bovis_AF2122/97 MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
Rv0165c|M.tuberculosis_H37Rv MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
MMAR_0408|M.marinum_M -----------------------------------------MNIPLSARR
MAV_5020|M.avium_104 ---------------------------------------------MSMQP
MUL_1833|M.ulcerans_Agy99 ----------------------------------MLEEEAVVIPRADSPD
MSMEG_5731|M.smegmatis_MC2_155 LQQLVAVAP--SQQAVLDELRRAILDGGVPPGTPIPLAEVAEVFGVSQIP
Mvan_0931|M.vanbaalenii_PYR-1 LGSLTVERPGGSQQVILDELRRAILDGAVPPGTPIPLAEVAEHFGVSRIP
MAB_2933c|M.abscessus_ATCC_199 INELRATRSGHDQTSVLDGLRRAILDGAAPPGSMIPIGEVADTYQISPIP
Mflv_0715|M.gilvum_PYR-GCK ---AGAVRREQLSDEVAARLRVEIMTGALRPESFIRLDETAARLGVSITP
TH_0156|M.thermoresistible__bu GPNGGGRRRDQLSDEVAAQLRAEIMSGALRPGTYIRLDETAARLGVSITP
Mb0170c|M.bovis_AF2122/97 -RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTP
Rv0165c|M.tuberculosis_H37Rv -RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTP
MMAR_0408|M.marinum_M -KSRRPLRRAQLSDEVAGHLRAAIMSGTLRPGTFIRLDETAAELGVSITP
MAV_5020|M.avium_104 -RSRRPLRRAQLSDEVAGHLRAAIMSGALRPGTFIRLDETAAELGVSVTP
MUL_1833|M.ulcerans_Agy99 QTCGRLPARGTVGEQVADLIQESILSGEAKRGSPLREELIADRYQVSRRT
: :: *: * : : * :* .
MSMEG_5731|M.smegmatis_MC2_155 VREALKTLIGEGLVAHRRNAGYTVALLTAQELREMYIVRETLESASLM--
Mvan_0931|M.vanbaalenii_PYR-1 VRESLKTLIGEGLVAHRANSGYMVAQLTAAELGELYVARESLEAASLA--
MAB_2933c|M.abscessus_ATCC_199 VREALKTLVAEGLVDHRANGGYRVAQLTLPELREIYFTRGVLERAALA--
Mflv_0715|M.gilvum_PYR-GCK VREALRTLRGEGMVELEPHRGHRVIPLSRNDIEDIFWLQSTIAQELAA--
TH_0156|M.thermoresistible__bu IREALRTLRGEGMVQLEPHRGHVVAPLTRGDIEDIFWLQATIARKLTA--
Mb0170c|M.bovis_AF2122/97 VREALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELAT--
Rv0165c|M.tuberculosis_H37Rv VREALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELAT--
MMAR_0408|M.marinum_M VREALLKLRGEGMVQLEPHRGHVVLPLTRQDIDDIFWLQATIARELAV--
MAV_5020|M.avium_104 VREALLKLRGEGMVQLEPHRGHVVLPLTRQDIEDIFWLQATIAKELAA--
MUL_1833|M.ulcerans_Agy99 VRDALRVLESNGLVRHQRHKGSTVVDFSAGDITDMYRSREVLELDAAKRW
:*::* * .:*:* . : * * :: :: ::: : :
MSMEG_5731|M.smegmatis_MC2_155 -AAVANATEADRDAAIAANAVLEQAIADDDAATYHRESRQFHAALTRPSR
Mvan_0931|M.vanbaalenii_PYR-1 -AAVGNASEADFATAIDMNALLEHAIREDDAVAYHRQSRRFHAALTGPSR
MAB_2933c|M.abscessus_ATCC_199 -QAAARATPEDVDRALAEHQLLQQATVEDDARAFHVHSRRFHRALVLPCG
Mflv_0715|M.gilvum_PYR-GCK -TATRRITEEQIEQLSRLNDTLASAVEQHDVQRIAQAEFEFHRTFNRAAG
TH_0156|M.thermoresistible__bu -AAVDRITDAELDELTALNEALAAAVDRGVVGEVAAAMSAFHRVLHRTTG
Mb0170c|M.bovis_AF2122/97 -SATAHITDVEIDELDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASR
Rv0165c|M.tuberculosis_H37Rv -SATAHITDVEIDELDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASR
MMAR_0408|M.marinum_M -TATERISEIDIGELEHINDALTAAVGAGDTEAIAALEFAFHRVLNQSSG
MAV_5020|M.avium_104 -AATDHITDTEIDELDRINDALAAAVGSGDAETIAGLEFGFHRVFNQASG
MUL_1833|M.ulcerans_Agy99 CRAGEVDSGYRFHRLTEALGRLEQASRGTDSGLIVKSDLDFHAAIIGLLD
* : * * ** .:
MSMEG_5731|M.smegmatis_MC2_155 MHRLLHMLEAAWNVTEPVQSMVHVRA----DERVQLHADHREMLDAFLMR
Mvan_0931|M.vanbaalenii_PYR-1 MYRLLRMLETAWNLTEPVQPMVHVTP----DDRIRLHADHGEMLQAFLTR
MAB_2933c|M.abscessus_ATCC_199 MHRLLHMFEATWNLTEPFQVMRTVSA----SDQLQLHADHEAMITAAASR
Mflv_0715|M.gilvum_PYR-GCK RVKLSWFLLHAARYLP--PQLFASDD----DWGAQAVVSHAELIAALRRG
TH_0156|M.thermoresistible__bu RIKLAWFLYHVARYMP--PQIYATDQ----QWGTATVARHRELIAALRRR
Mb0170c|M.bovis_AF2122/97 RIKLAWFLLNAARYMP--AQVFAADP----RWGADAVNSHRQLIAALRRR
Rv0165c|M.tuberculosis_H37Rv RIKLAWFLLNAARYMG--AGVRGRP--------AMGRGRGEQSSAADRR-
MMAR_0408|M.marinum_M RIKLAWFLLNAARYMP--AQLYASDP----QWGAAAVDNHRQLIAALRRR
MAV_5020|M.avium_104 RIKLAWFLLNAARYMP--VLVYAADP----QWGRAAVDNHRQLIAALRRR
MUL_1833|M.ulcerans_Agy99 SPRVDRFFAAIEAEMLYALAILEASEGEYKTDAAKAFGEHKAMYEALRDR
:: :: : *
MSMEG_5731|M.smegmatis_MC2_155 DAERLVAASEAHAARLNAVIAVLPTGTGLLA---------
Mvan_0931|M.vanbaalenii_PYR-1 DVERLLGAAERHARRLNSVIATLSFETGLLAAEKDISSPQ
MAB_2933c|M.abscessus_ATCC_199 DIDTLLSVAATHHDRLESVIVAAAGQLDVVAEA-------
Mflv_0715|M.gilvum_PYR-GCK DVDVVVELTRGQFTDGLHRLIAWLEQVGLWS---------
TH_0156|M.thermoresistible__bu DTETATRVTVDLFTDSAQRLIAQLEKVGIWT---------
Mb0170c|M.bovis_AF2122/97 DTAAVIEHTVWQFTDGARRLTEALAETEVFG---------
Rv0165c|M.tuberculosis_H37Rv --AAPPRHSRR---NRAHRLAVHRWGTQADGGPG------
MMAR_0408|M.marinum_M DTAAVIEHSVWQFTDAAHRLTQMLETNGIFN---------
MAV_5020|M.avium_104 DTAAVIEHTVWQFTDAAARLTAMRDRTGTPSNRG------
MUL_1833|M.ulcerans_Agy99 DEQRSTQLISEHLRINRDVLIRIVAS--------------
: