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TETAVPNAGGGPAGPDGSFPVAAGDLVEAAGHPIGSGAIKPGYDPRLTNEDLAPLRQQKWGSYNIFAFWM SDVHSVGGYVTAGSLFALGLASWQVLVALLIGISIVNVFCNLVAKPSQQTGVPYPVICRTVFGVLGANIP AIIRGLIAVAWYGIQTFLASAALDIVLVKLFPALAPYAVVDDYGFAGLSLLGWGSFLLLWVLQACVFWRG MESIRKFIDFCGPAVYVVMFLLCGYLIFQAGWGAIDLSLGEVTYTGWSSVPVMLGAIALVVSYFSGPMLN FGDFSRYGRTFAAVKKGNFLGLPVNFLVFSVLVVVTASLTLPVFGELITDPVETVARIDSTFAIVLGALT FAIATIGINIVANFISPAFDFSNVSPQRISWRAGGMIAAVGSVLITPWNLYNNPEVIHYTLETLGAFIGP LFGVLIADFYLVRKQKVIVDDMFTLDESGKYWYTKGYNKVAVIATVVGAVLAVIPVLLGGSVAGMHTAAQ YSWFIGCGIAFGLYYVLAKRDTLVAASVS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5730 | - | - | 100% (520) | permease for cytosine/purines, uracil, thiamine, allantoin transporter |
| M. smegmatis MC2 155 | MSMEG_3556 | - | 7e-63 | 30.20% (500) | integral membrane transporter |
| M. smegmatis MC2 155 | MSMEG_2972 | - | 2e-16 | 24.76% (513) | permease, cytosine/purines, uracil, thiamine, allantoin family |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3170 | - | 1e-105 | 42.46% (471) | permease for cytosine/purines, uracil, thiamine, allantoin |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2936 | - | 0.0 | 64.50% (493) | putative cytosine/purine/uracil/thiamine/ allantoin permease |
| M. marinum M | MMAR_1212 | - | 0.0 | 79.18% (490) | hypothetical protein MMAR_1212 |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2680 | - | 0.0 | 80.71% (451) | hypothetical protein MUL_2680 |
| M. vanbaalenii PYR-1 | Mvan_0932 | - | 0.0 | 88.17% (524) | permease for cytosine/purines, uracil, thiamine, allantoin |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5730|M.smegmatis_MC2_155 -----MTETAVPNAGGGPAGPDGS---FPVAAGDLVEAAGH-PIGSG---
Mvan_0932|M.vanbaalenii_PYR-1 -----MTDTAP--APPSRKLPPG----AVVGADDLVEAAGH-PVGAG---
MMAR_1212|M.marinum_M -----MIDTTAP--------------------HSPVHSPSH-GAGPA---
MUL_2680|M.ulcerans_Agy99 -----MIDTTAP--------------------HSPVHSPSH-GAGPA---
MAB_2936|M.abscessus_ATCC_1997 -----MSGVLTA--------------------DAVAPTGGHSAAGDS---
Mflv_3170|M.gilvum_PYR-GCK MSVCALLSKLVEYYFRKVEFSGDARVGAPTVTGVSMSTESTGLIGDSSRN
: : . * .
MSMEG_5730|M.smegmatis_MC2_155 --AIKPGYDPRLTNEDLAPLRQQ--KWGSYNIFAFWMSDVHSVGGYVTAG
Mvan_0932|M.vanbaalenii_PYR-1 --RIEPGYDPRLTNEDLAPLRKQ--TWTSYNIFAFWMSDVHSVGGYVTAG
MMAR_1212|M.marinum_M --NIKPDYHPRLTNDDLAPLREQ--TWGTYNIFAFWMSDVHSVGGYVTAG
MUL_2680|M.ulcerans_Agy99 --NIKPDYHPRLTNDDLAPLREQ--TWGTYNIFAFWMSDVHSVGGYVTAG
MAB_2936|M.abscessus_ATCC_1997 --VIKPGYDPALTNGDLAPLRTQ--TWTSYNFFAFWMSDVHSVGGYVFAG
Mflv_3170|M.gilvum_PYR-GCK DHTALAGVSPHLYNPDLAPTKRAGRRWGSYNIFTLWANDVHSLGNYSFAI
.. * * * **** : * :**:*::* .****:*.* *
MSMEG_5730|M.smegmatis_MC2_155 SLFALGLASWQVLVALLIGISIVNVFCNLVAKPSQQTGVPYPVICRTVFG
Mvan_0932|M.vanbaalenii_PYR-1 SLFALGLASWQVLVALLAGITIVYYLCNLVAKPSQATGVPYPVICRTVFG
MMAR_1212|M.marinum_M SLFALGLASWQVLVSLVIAITIVYFLCNLVARPSQATGVPYPVICRTAFG
MUL_2680|M.ulcerans_Agy99 SLFALGLASWQVLVSLVIAITIVYFLCNLVARPSQATGVPYPVICRTAFG
MAB_2936|M.abscessus_ATCC_1997 SLFALGISASQVLLALLVGIAAVYWLCNLVARPSQQTGVPYPVTARIAFG
Mflv_3170|M.gilvum_PYR-GCK GLFALGLGGWQILLALGLGGVFLFLLLNLSGFMGEKTGVPFPVMSRIAFG
.*****:.. *:*::* . : : ** . .: ****:** .* .**
MSMEG_5730|M.smegmatis_MC2_155 VLGANIPAIIRGLIAVAWYGIQTFLASAALDIVLVKLFPALAPYAVVDDY
Mvan_0932|M.vanbaalenii_PYR-1 VLGANIPAIIRGLIAVAWYGIQTFLASAALDIVLIKLFPALAPYAVVEDF
MMAR_1212|M.marinum_M VLGANIPAIIRGLIAVAWYGIQTYLASAALDVVMIKLFPGLARYAVVEDY
MUL_2680|M.ulcerans_Agy99 VLGANIPAIIRGLIAVAWYGIQTYLASAALDVVMIKLFPGLARYAVVEDY
MAB_2936|M.abscessus_ATCC_1997 VRGANLPAVIRGLIAVAWYGIQTYLASTAFVLLAVKFQPSLGRYGNAGEY
Mflv_3170|M.gilvum_PYR-GCK IRGAQIPALIRGAVAIAWFGIQTYLASVVLRIMIIALAPSAES---LDSN
: **::**:*** :*:**:****:***..: :: : : *. .
MSMEG_5730|M.smegmatis_MC2_155 GFAGLSLLGWGSFLLLWVLQACVFWRGMESIRKFIDFCGPAVYVVMFLLC
Mvan_0932|M.vanbaalenii_PYR-1 GFAGLSLLGWCSFLLLWVLQACVFWRGMESIRKFIDFCGPAVYVVMFLLC
MMAR_1212|M.marinum_M GFLGLPALGWASYLILWVLQACVFWRGMEAIRKFIDFCGPAVYVVMFALS
MUL_2680|M.ulcerans_Agy99 GFLGLPALGWASYLILWVLQACVFWRGMEAIRKFIDFCGPAVYVVIFALS
MAB_2936|M.abscessus_ATCC_1997 GFLGLSLLGWGGFLLMWVLQAAVFWNGMEAIRKFIDFCGPAVYAVMLALA
Mflv_3170|M.gilvum_PYR-GCK SVLGLSTLGWISFVVLWVVRVIIVSYGMEMIRRYEAFAGPVILVTMIALA
.. **. *** .::::**::. :. *** **:: *.**.: ..:: *.
MSMEG_5730|M.smegmatis_MC2_155 GYLIFQAGWGAIDLSLG-EVTYTGWSSVPVMLGAIALVVSYFSGPMLNFG
Mvan_0932|M.vanbaalenii_PYR-1 GYLISEAGWGAIDLNLG-DVTYTGWSSVPVMLGAIALVVSYFSGPMLNFG
MMAR_1212|M.marinum_M GYLISKAGWAAIDLNLG-DVRYSGWDAIPVMLGAIALVVSYFSGPMLNFG
MUL_2680|M.ulcerans_Agy99 GYLISTAGWAAIDLNLG-DVRYSGWDAIPVMLGAIALVVSYFSGPMLNFG
MAB_2936|M.abscessus_ATCC_1997 LYLVVAAGWENVHFGLASGPPKSGFAALATILSAIALVVSYFSGPMLNFG
Mflv_3170|M.gilvum_PYR-GCK VWMLNNADWS-IAWSTP--DSLTGVDMWLKIIGGASLWVAIYGTFVLNFC
::: *.* : . :* ::.. :* *: :. :***
MSMEG_5730|M.smegmatis_MC2_155 DFSRYGRTFAAVKKGNFLGLPVNFLVFSVLVVVTASLTLPVFG-----EL
Mvan_0932|M.vanbaalenii_PYR-1 DFSRYGKSFEAVKKGNFLGLPVNFLLFSVLVVVTASLTLPVFG-----EL
MMAR_1212|M.marinum_M DFSRYGRSFGAVRKGNFLGLPLNFLLFSLLVVVTASLTVPVFG-----EL
MUL_2680|M.ulcerans_Agy99 DFSRYGRSFGAVRKGNFLGLPLNFLLFSLLVVVTASLTVPVFG-----EL
MAB_2936|M.abscessus_ATCC_1997 DFSRYGRTFGEVKRGNFLGLPLNFLFFAVLAVCTVSAGATVIGRGEDGAI
Mflv_3170|M.gilvum_PYR-GCK DFTRNATSKRAIVHGNFWGIPLNMLVFGGIVITLAGAQFRIDG-----RI
**:* . : : :*** *:*:*:*.*. :.: .. : * :
MSMEG_5730|M.smegmatis_MC2_155 ITDPVETVARIDSTFAIVLGALTFAIATIGINIVANFISPAFDFSNVSPQ
Mvan_0932|M.vanbaalenii_PYR-1 ITDPVETVARIDSTFAIVLGALTFATATIGINIVANFISPAFDFSNVSPQ
MMAR_1212|M.marinum_M ITDPVQTVARIDSTFAIILGASTFTIATIGINIVANFISPAFDFSNVNPQ
MUL_2680|M.ulcerans_Agy99 ITDPVQTVARIDSTFAIILGASTFTIATIGINIVANFISPAFDFSNVNPQ
MAB_2936|M.abscessus_ATCC_1997 ITDPVLIVDKINNTTAAVLGVLTFAIATIGINIVANFVSPAFDFSNLAPT
Mflv_3170|M.gilvum_PYR-GCK IEAPADIVQEVPNTFLLVLAALALLILTIAVNLMANFVAPIYALNNLFPK
* *. * .: .* :*.. :: **.:*::***::* : :.*: *
MSMEG_5730|M.smegmatis_MC2_155 RISWRAGGMIAAVGSVLITPWNLYNNPEVIHYTLETLGAFIGPLFGVLIA
Mvan_0932|M.vanbaalenii_PYR-1 RISWRAGGMIAAVGSVLITPWNLYNNPEVIHYTLETLGAFIGPLFGVLIA
MMAR_1212|M.marinum_M RISWRTGGMIAAVGSALITPWNLYNHPDVIHYTLETLGAFIGPLFGVLIA
MUL_2680|M.ulcerans_Agy99 RIGWRTGGMIAAVGSALITPWNLYNHPDVIHYTLETLGAFIGPLFGVLIA
MAB_2936|M.abscessus_ATCC_1997 RISWRTGGMIAAVGSILITPWNLYNNPNTIHYTLDALGAVIGPLFGILIA
Mflv_3170|M.gilvum_PYR-GCK HLNFRRAAFISAVIGLVILPWNLYNTPAVINYFLGGLGAILGPLFGIIMA
::.:* ..:*:** . :* ****** * .*:* * ***.:*****:::*
MSMEG_5730|M.smegmatis_MC2_155 DFYLVRKQKVIVDDMFTLDESGKYWYTKGYNKVAVIATVVGAVLAVIPVL
Mvan_0932|M.vanbaalenii_PYR-1 DYYLVRKQQVVVDDLFTMEESGKYWYTKGYNRVAVLATAVGAVLAVVPVL
MMAR_1212|M.marinum_M DYYLVRKQHVVVDDLFSLSHDGTYWYRKGYNPAAVIATAVSAAIAMVPVL
MUL_2680|M.ulcerans_Agy99 DYYLVRKQHVVVDDLFSLSHDGTYWYRKGYNPAAVIATAVSAAIAMAPVL
MAB_2936|M.abscessus_ATCC_1997 DFYLVRRRAVVVDDLFTLSPSGTYQYRGGINPIAVTATVLGALLAIATVI
Mflv_3170|M.gilvum_PYR-GCK DYWLVRRSKINVLALFTTDADGEYHYAKGVNVRAVIALVITAVAALLLAF
*::***: : * :*: . .* * * * * ** * .: * *: .:
MSMEG_5730|M.smegmatis_MC2_155 LGGSVAGMHTAAQYSWFIGCGIAFGLYYVLA-KRDTLVAASVS-------
Mvan_0932|M.vanbaalenii_PYR-1 LGGSVAGMATAAQYSWFIGCGVAFAIYYLVA-KRDTLVAASLS-------
MMAR_1212|M.marinum_M AS-DVYGMYTAAEYSWFIGCGVALVVYYLLA-TRGRLAIAPPYHPVGAG-
MUL_2680|M.ulcerans_Agy99 AS-DV---------------------------------------------
MAB_2936|M.abscessus_ATCC_1997 WG-----SPYLATFTWFVGAGIGFAVYLVGM-RYTPRHLIYGR-------
Mflv_3170|M.gilvum_PYR-GCK VP----AFAVVAEFSWFIGAGLGAIVYLVVADRRGPFNDVSGEPIAVDST
MSMEG_5730|M.smegmatis_MC2_155 -
Mvan_0932|M.vanbaalenii_PYR-1 -
MMAR_1212|M.marinum_M -
MUL_2680|M.ulcerans_Agy99 -
MAB_2936|M.abscessus_ATCC_1997 -
Mflv_3170|M.gilvum_PYR-GCK H