For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSTRPIEPVAAGDDSPPEQSAAVPFDAHGIEPIAPTDRDCSPAELFWIWCGANIAPINWVLGALGITLGL SLVETLIVVAVGNLLGCAVFGVFNVIGHRTAVNQMVLGRAPFGRMGARIPGLVQFLLTMGWVGVNTWVVL DLVLAVFAEFGVTGGLWLEVVVAAGIMVIQLALALYGFYAIRSFEKYTVPATAVVMAVMTALAFAATDVQ WSLAGHAMTAGEKFTAVTQLLTAIGIGWGLTWIPYASDYSRFVRVGASSRSVFWASSLGMYVPTVWLAAV GACLASAGTGSDPSALVVSTFGIMAVPVLLLLVHGPIATNILNLYSCSLAALSIGVRMTRWKVTLLAGAV ASVVLAVFVQADSFAHAFDNWLVSILVWISPWAAIMLVDYVVLRRGALDVTSLYREDSARWNHAGLVSLA VGIVAGWSWQYGLVPAMQGPIATSFGNTDFSWLSGSLVAGGLYWVLRRRATGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2972 | - | - | 100% (473) | permease, cytosine/purines, uracil, thiamine, allantoin family protein |
| M. smegmatis MC2 155 | MSMEG_6660 | - | e-118 | 46.74% (430) | permease, cytosine/purines, uracil, thiamine, allantoin family |
| M. smegmatis MC2 155 | MSMEG_1683 | - | 1e-45 | 29.48% (458) | cytosine/purine/uracil/thiamine/allantoin permease family |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0055 | - | 1e-118 | 47.67% (430) | permease for cytosine/purines, uracil, thiamine, allantoin |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2025 | - | 1e-32 | 26.55% (452) | purine/cytosine permease |
| M. marinum M | MMAR_1212 | - | 2e-14 | 24.55% (444) | hypothetical protein MMAR_1212 |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2680 | - | 7e-10 | 24.24% (396) | hypothetical protein MUL_2680 |
| M. vanbaalenii PYR-1 | Mvan_0862 | - | 1e-120 | 44.81% (482) | permease for cytosine/purines, uracil, thiamine, allantoin |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0055|M.gilvum_PYR-GCK --------------------------------------------MHDLEA
Mvan_0862|M.vanbaalenii_PYR-1 MIRDELRMDSPAQRGATRPSIPDESGSPMTSVDTAPAPPGPPHGGHDLEA
MSMEG_2972|M.smegmatis_MC2_155 -----------------------MSTRPIEPVAAGDDSPPEQSAAVPFDA
MMAR_1212|M.marinum_M ---------------------MIDTTAPHSPVHSPSHGAGPANIKPDYHP
MUL_2680|M.ulcerans_Agy99 ---------------------MIDTTAPHSPVHSPSHGAGPANIKPDYHP
MAB_2025|M.abscessus_ATCC_1997 -------------------MDEIQACCSATSLIASRESVGRDRVGAIERA
.
Mflv_0055|M.gilvum_PYR-GCK E---LTVIPESAKTTDLRGQFWIWAGANIAPINWILGALGVTMGLGLFET
Mvan_0862|M.vanbaalenii_PYR-1 E---LTVIPESAKTTDLRGQFWIWAGANIAPINWILGALGVTMGLGLFET
MSMEG_2972|M.smegmatis_MC2_155 HG--IEPIAPTDRDCSPAELFWIWCGANIAPINWVLGALGITLGLSLVET
MMAR_1212|M.marinum_M RLTNDDLAPLREQTWGTYNIFAFWMSDVHSVGGYVTAGSLFALGLASWQV
MUL_2680|M.ulcerans_Agy99 RLTNDDLAPLREQTWGTYNIFAFWMSDVHSVGGYVTAGSLFALGLASWQV
MAB_2025|M.abscessus_ATCC_1997 G---IDYLPEAARGSSPKNLFAVFVGGNLAFSTIIFGWLPIVMGLTFWQA
. : . * .: . : : . ..:** :.
Mflv_0055|M.gilvum_PYR-GCK IAVLVVGNAIGMSLFGTFVVIGQKTGVTGMVLSRMVFGRRGAYVPAAVQA
Mvan_0862|M.vanbaalenii_PYR-1 IAVLVVGNAIGMSLFGLFVVIGQRTGVTGMVFSRAVFGRRGAYVPAAVQA
MSMEG_2972|M.smegmatis_MC2_155 LIVVAVGNLLGCAVFGVFNVIGHRTAVNQMVLGRAPFGRMGARIPGLVQF
MMAR_1212|M.marinum_M LVSLVIAITIVYFLCNLVARPSQATGVPYPVICRTAFGVLGANIPAIIRG
MUL_2680|M.ulcerans_Agy99 LVSLVIAITIVYFLCNLVARPSQATGVPYPVICRTAFGVLGANIPAIIRG
MAB_2025|M.abscessus_ATCC_1997 VSSSVTGLLIGLMLTAPMSLFGPRTGTNNPVSSGAHFGVRGRLIGSSLTL
: . . : : . . *.. * ** * : . :
Mflv_0055|M.gilvum_PYR-GCK ALCIGWCAVNTWIV---LDLVMALLG----RIGLVDPE--LSNHAARIVV
Mvan_0862|M.vanbaalenii_PYR-1 VLCIGWCAVNTWIV---LDLVMALLG----RIGLVDPE--LSNNAARILV
MSMEG_2972|M.smegmatis_MC2_155 LLTMGWVGVNTWVV---LDLVLAVFA----EFGVTG------GLWLEVVV
MMAR_1212|M.marinum_M LIAVAWYGIQTYLASAALDVVMIKLFPGLARYAVVEDYGFLGLPALGWAS
MUL_2680|M.ulcerans_Agy99 LIAVAWYGIQTYLASAALDVVMIKLFPGLARYAVVEDYGFLGLPALGWAS
MAB_2025|M.abscessus_ATCC_1997 MFALVYAAIAVWTSG---EALIAGAS------RLFGAP---QNHVAFLLG
: : : .: .: : :: :
Mflv_0055|M.gilvum_PYR-GCK AGIIMTTQVVIAWFGYRLIAAFERWTVPPTVAVLVAMT--AVAWFGLDVD
Mvan_0862|M.vanbaalenii_PYR-1 AGVIMTIQVAIAWFGYRVIAAFERWTVPPTVAVLVAMT--VVAWIGLDVD
MSMEG_2972|M.smegmatis_MC2_155 AAGIMVIQLALALYGFYAIRSFEKYTVPATAVVMAVMT--ALAFAATDVQ
MMAR_1212|M.marinum_M YLILWVLQACVFWRGMEAIRKFIDFCGPAVYVVMFALSGYLISKAGWAAI
MUL_2680|M.ulcerans_Agy99 YLILWVLQACVFWRGMEAIRKFIDFCGPAVYVVIFALSGYLISTAGWAAI
MAB_2025|M.abscessus_ATCC_1997 YGVIALEVILIALYGHATIVWAQKIIIP-LAVVVLALGVLAYAPNFHPMG
: : * * * .*: .: :
Mflv_0055|M.gilvum_PYR-GCK WGYTGDAALTGAEHFTAITAVMTAIGIGWGITWLGYAGDYSRFVSSSVPA
Mvan_0862|M.vanbaalenii_PYR-1 WAYAGDTTLTGAEHFTAITAVMTAIGIGWGITWLGYAGDYSRFVSAQVPA
MSMEG_2972|M.smegmatis_MC2_155 WSLAG-HAMTAGEKFTAVTQLLTAIGIGWGLTWIPYASDYSRFVRVGASS
MMAR_1212|M.marinum_M DLNLGDVRYSGWDAIPVMLGAIALVVSYFSGPMLNFG-DFSRYGRSFGAV
MUL_2680|M.ulcerans_Agy99 DLNLGDVRYSGWDAIPVMLGAIALVVSYFSGPMLNFG-DFSRYGRSFGAV
MAB_2025|M.abscessus_ATCC_1997 SAQHGYALQEFWPTWLFAVTVSVGGPLSYAPSVGDYTRRISRSRYSDRQI
* . :. . : **
Mflv_0055|M.gilvum_PYR-GCK RKLFAASALGQFIPVVWLGALGATLATLSASSDPGEIIVDAYGVLAIPVL
Mvan_0862|M.vanbaalenii_PYR-1 RKLFAASALGQFIPVVWLGALGASLATLSTSSDPGEIIVDAYGALAIPVL
MSMEG_2972|M.smegmatis_MC2_155 RSVFWASSLGMYVPTVWLAAVGACLASAGTGSDPSALVVSTFGIMAVPVL
MMAR_1212|M.marinum_M RKGNFLGLPLNFLLFSLLVVVTASLTVPVFGELITDPVQTVARIDSTFAI
MUL_2680|M.ulcerans_Agy99 RKGNFLGLPLNFLLFSLLVVVTASLTVPVFGELITDPVQTVARIDSTFAI
MAB_2025|M.abscessus_ATCC_1997 AVAVSAGIFLGLFSTATFGAFTASTFSAPTASYVADMVATAPGWYVVPLL
. . : .. * .. : . :
Mflv_0055|M.gilvum_PYR-GCK LL----VVHGPLATNILN-IYTCAVSTQALDIHVNRRVLNIVIGVVAMAW
Mvan_0862|M.vanbaalenii_PYR-1 LL----VVHGPLATNILN-IYTCAVSTQALDIKVNRRVLNVVIGVVAMAC
MSMEG_2972|M.smegmatis_MC2_155 LL----LVHGPIATNILN-LYSCSLAALSIGVRMTRWKVTLLAGAVASVV
MMAR_1212|M.marinum_M ILGASTFTIATIGINIVANFISPAFDFSNVNPQRISWRTGGMIAAVGSAL
MUL_2680|M.ulcerans_Agy99 ILGASTFTIATIGINIVANFISPAFDFSNVNPQRIGWRTGGMIAAVGSAL
MAB_2025|M.abscessus_ATCC_1997 IL----AVLGGCGQGVIS-IYSSGLDLESIVPRLNRTQTTLIASGIAVVL
:* . . . .:: : : .. : : : . :. .
Mflv_0055|M.gilvum_PYR-GCK VVYFVLNGDFAATIDAWLVGIVGWLAPWAAVMLVHWFGVARRQVDPATLL
Mvan_0862|M.vanbaalenii_PYR-1 VVYFVLNGDFAQTIDAWLVGIVGWVSPWAAVMLVHWFGVARRQVDAATLL
MSMEG_2972|M.smegmatis_MC2_155 LAVFVQADSFAHAFDNWLVSILVWISPWAAIMLVDYVVLRRGALDVTSLY
MMAR_1212|M.marinum_M ITPWNLYN-HPDVIHYTLETLGAFIGPLFGVLIADYYLVRKQHVVVDDLF
MUL_2680|M.ulcerans_Agy99 ITPWNLYN-HPDVIHYTLETLGAFIGPLFGVLIADYYLVRKQHVVVDDLF
MAB_2025|M.abscessus_ATCC_1997 MYLGVVVTDAIDSVTGMTVVLNSFAGSWVAINICGFFKANRGQYDPKALQ
: . : : .. .: : : : *
Mflv_0055|M.gilvum_PYR-GCK TPPNESTLPAVRPSALISLAVGIVFTWLFMYGMVPMM----QGPIAVALG
Mvan_0862|M.vanbaalenii_PYR-1 TPPGESTLPTVRLSALFALAVGIVFTWLFMYGMVPVM----QGPIAIALG
MSMEG_2972|M.smegmatis_MC2_155 REDS----ARWNHAGLVSLAVGIVAGWSWQYGLVPAM----QGPIATSFG
MMAR_1212|M.marinum_M SLSHDG---TYWYRKGYNPAAVIATAVSAAIAMVPVL----ASDVYGMYT
MUL_2680|M.ulcerans_Agy99 SLSHDG---TYWYRKGYNPAAVIATAVSAAIAMAPVL----ASDV-----
MAB_2025|M.abscessus_ATCC_1997 RFGQDGRGGLYWFSHGFNVRAVVPFIAGSGLGLLTVQNDLYQAPFANIAG
. : .: . . .
Mflv_0055|M.gilvum_PYR-GCK GVDLSWLAGGLAAGSLYAALEIPKARRA----------
Mvan_0862|M.vanbaalenii_PYR-1 GVDLSWLAGGLAAGTIYAALEIPRARRVRT--------
MSMEG_2972|M.smegmatis_MC2_155 NTDFSWLSGSLVAGGLYWVLRRRATGR-----------
MMAR_1212|M.marinum_M AAEYSWFIGCGVALVVYYLLATRGRLAIAPPYHPVGAG
MUL_2680|M.ulcerans_Agy99 --------------------------------------
MAB_2025|M.abscessus_ATCC_1997 GIDVSLLLSVVVGGGLYWLAQVSWPAPRVVSSGSSA--