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MTDTAPAPPSRKLPPGAVVGADDLVEAAGHPVGAGRIEPGYDPRLTNEDLAPLRKQTWTSYNIFAFWMSD VHSVGGYVTAGSLFALGLASWQVLVALLAGITIVYYLCNLVAKPSQATGVPYPVICRTVFGVLGANIPAI IRGLIAVAWYGIQTFLASAALDIVLIKLFPALAPYAVVEDFGFAGLSLLGWCSFLLLWVLQACVFWRGME SIRKFIDFCGPAVYVVMFLLCGYLISEAGWGAIDLNLGDVTYTGWSSVPVMLGAIALVVSYFSGPMLNFG DFSRYGKSFEAVKKGNFLGLPVNFLLFSVLVVVTASLTLPVFGELITDPVETVARIDSTFAIVLGALTFA TATIGINIVANFISPAFDFSNVSPQRISWRAGGMIAAVGSVLITPWNLYNNPEVIHYTLETLGAFIGPLF GVLIADYYLVRKQQVVVDDLFTMEESGKYWYTKGYNRVAVLATAVGAVLAVVPVLLGGSVAGMATAAQYS WFIGCGVAFAIYYLVAKRDTLVAASLS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0932 | - | - | 100% (517) | permease for cytosine/purines, uracil, thiamine, allantoin |
| M. vanbaalenii PYR-1 | Mvan_0862 | - | 1e-11 | 22.90% (524) | permease for cytosine/purines, uracil, thiamine, allantoin |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3170 | - | 1e-104 | 42.04% (471) | permease for cytosine/purines, uracil, thiamine, allantoin |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2936 | - | 1e-180 | 63.60% (500) | putative cytosine/purine/uracil/thiamine/ allantoin permease |
| M. marinum M | MMAR_1212 | - | 0.0 | 81.22% (490) | hypothetical protein MMAR_1212 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5730 | - | 0.0 | 88.17% (524) | permease for cytosine/purines, uracil, thiamine, allantoin |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2680 | - | 0.0 | 82.48% (451) | hypothetical protein MUL_2680 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0932|M.vanbaalenii_PYR-1 --------------MTDTAPAPPSRKLPPG----AVVGADDLVEAAGHPV
MSMEG_5730|M.smegmatis_MC2_155 --------------MTETA-VPNAGGGPAGPDGSFPVAAGDLVEAAGHPI
MMAR_1212|M.marinum_M --------------MIDTT-APHSP-----------------VHSPSHGA
MUL_2680|M.ulcerans_Agy99 --------------MIDTT-APHSP-----------------VHSPSHGA
MAB_2936|M.abscessus_ATCC_1997 --------------MSGVLTADAVAP-----------------TGGHSAA
Mflv_3170|M.gilvum_PYR-GCK MSVCALLSKLVEYYFRKVEFSGDARVGAPTVTG-VSMSTESTGLIGDSSR
: .
Mvan_0932|M.vanbaalenii_PYR-1 GAGRIEPGYDPRLTNEDLAPLRKQ--TWTSYNIFAFWMSDVHSVGGYVTA
MSMEG_5730|M.smegmatis_MC2_155 GSGAIKPGYDPRLTNEDLAPLRQQ--KWGSYNIFAFWMSDVHSVGGYVTA
MMAR_1212|M.marinum_M GPANIKPDYHPRLTNDDLAPLREQ--TWGTYNIFAFWMSDVHSVGGYVTA
MUL_2680|M.ulcerans_Agy99 GPANIKPDYHPRLTNDDLAPLREQ--TWGTYNIFAFWMSDVHSVGGYVTA
MAB_2936|M.abscessus_ATCC_1997 GDSVIKPGYDPALTNGDLAPLRTQ--TWTSYNFFAFWMSDVHSVGGYVFA
Mflv_3170|M.gilvum_PYR-GCK NDHTALAGVSPHLYNPDLAPTKRAGRRWGSYNIFTLWANDVHSLGNYSFA
. .. * * * **** : * :**:*::* .****:*.* *
Mvan_0932|M.vanbaalenii_PYR-1 GSLFALGLASWQVLVALLAGITIVYYLCNLVAKPSQATGVPYPVICRTVF
MSMEG_5730|M.smegmatis_MC2_155 GSLFALGLASWQVLVALLIGISIVNVFCNLVAKPSQQTGVPYPVICRTVF
MMAR_1212|M.marinum_M GSLFALGLASWQVLVSLVIAITIVYFLCNLVARPSQATGVPYPVICRTAF
MUL_2680|M.ulcerans_Agy99 GSLFALGLASWQVLVSLVIAITIVYFLCNLVARPSQATGVPYPVICRTAF
MAB_2936|M.abscessus_ATCC_1997 GSLFALGISASQVLLALLVGIAAVYWLCNLVARPSQQTGVPYPVTARIAF
Mflv_3170|M.gilvum_PYR-GCK IGLFALGLGGWQILLALGLGGVFLFLLLNLSGFMGEKTGVPFPVMSRIAF
.*****:.. *:*::* . : : ** . .: ****:** .* .*
Mvan_0932|M.vanbaalenii_PYR-1 GVLGANIPAIIRGLIAVAWYGIQTFLASAALDIVLIKLFPALAPYAVVED
MSMEG_5730|M.smegmatis_MC2_155 GVLGANIPAIIRGLIAVAWYGIQTFLASAALDIVLVKLFPALAPYAVVDD
MMAR_1212|M.marinum_M GVLGANIPAIIRGLIAVAWYGIQTYLASAALDVVMIKLFPGLARYAVVED
MUL_2680|M.ulcerans_Agy99 GVLGANIPAIIRGLIAVAWYGIQTYLASAALDVVMIKLFPGLARYAVVED
MAB_2936|M.abscessus_ATCC_1997 GVRGANLPAVIRGLIAVAWYGIQTYLASTAFVLLAVKFQPSLGRYGNAGE
Mflv_3170|M.gilvum_PYR-GCK GIRGAQIPALIRGAVAIAWFGIQTYLASVVLRIMIIALAPSAES---LDS
*: **::**:*** :*:**:****:***..: :: : : *. .
Mvan_0932|M.vanbaalenii_PYR-1 FGFAGLSLLGWCSFLLLWVLQACVFWRGMESIRKFIDFCGPAVYVVMFLL
MSMEG_5730|M.smegmatis_MC2_155 YGFAGLSLLGWGSFLLLWVLQACVFWRGMESIRKFIDFCGPAVYVVMFLL
MMAR_1212|M.marinum_M YGFLGLPALGWASYLILWVLQACVFWRGMEAIRKFIDFCGPAVYVVMFAL
MUL_2680|M.ulcerans_Agy99 YGFLGLPALGWASYLILWVLQACVFWRGMEAIRKFIDFCGPAVYVVIFAL
MAB_2936|M.abscessus_ATCC_1997 YGFLGLSLLGWGGFLLMWVLQAAVFWNGMEAIRKFIDFCGPAVYAVMLAL
Mflv_3170|M.gilvum_PYR-GCK NSVLGLSTLGWISFVVLWVVRVIIVSYGMEMIRRYEAFAGPVILVTMIAL
.. **. *** .::::**::. :. *** **:: *.**.: ..:: *
Mvan_0932|M.vanbaalenii_PYR-1 CGYLISEAGWGAIDLNLG-DVTYTGWSSVPVMLGAIALVVSYFSGPMLNF
MSMEG_5730|M.smegmatis_MC2_155 CGYLIFQAGWGAIDLSLG-EVTYTGWSSVPVMLGAIALVVSYFSGPMLNF
MMAR_1212|M.marinum_M SGYLISKAGWAAIDLNLG-DVRYSGWDAIPVMLGAIALVVSYFSGPMLNF
MUL_2680|M.ulcerans_Agy99 SGYLISTAGWAAIDLNLG-DVRYSGWDAIPVMLGAIALVVSYFSGPMLNF
MAB_2936|M.abscessus_ATCC_1997 ALYLVVAAGWENVHFGLASGPPKSGFAALATILSAIALVVSYFSGPMLNF
Mflv_3170|M.gilvum_PYR-GCK AVWMLNNADWS-IAWSTP--DSLTGVDMWLKIIGGASLWVAIYGTFVLNF
. ::: *.* : . :* ::.. :* *: :. :***
Mvan_0932|M.vanbaalenii_PYR-1 GDFSRYGKSFEAVKKGNFLGLPVNFLLFSVLVVVTASLTLPVFG-----E
MSMEG_5730|M.smegmatis_MC2_155 GDFSRYGRTFAAVKKGNFLGLPVNFLVFSVLVVVTASLTLPVFG-----E
MMAR_1212|M.marinum_M GDFSRYGRSFGAVRKGNFLGLPLNFLLFSLLVVVTASLTVPVFG-----E
MUL_2680|M.ulcerans_Agy99 GDFSRYGRSFGAVRKGNFLGLPLNFLLFSLLVVVTASLTVPVFG-----E
MAB_2936|M.abscessus_ATCC_1997 GDFSRYGRTFGEVKRGNFLGLPLNFLFFAVLAVCTVSAGATVIGRGEDGA
Mflv_3170|M.gilvum_PYR-GCK CDFTRNATSKRAIVHGNFWGIPLNMLVFGGIVITLAGAQFRIDG-----R
**:* . : : :*** *:*:*:*.*. :.: .. : *
Mvan_0932|M.vanbaalenii_PYR-1 LITDPVETVARIDSTFAIVLGALTFATATIGINIVANFISPAFDFSNVSP
MSMEG_5730|M.smegmatis_MC2_155 LITDPVETVARIDSTFAIVLGALTFAIATIGINIVANFISPAFDFSNVSP
MMAR_1212|M.marinum_M LITDPVQTVARIDSTFAIILGASTFTIATIGINIVANFISPAFDFSNVNP
MUL_2680|M.ulcerans_Agy99 LITDPVQTVARIDSTFAIILGASTFTIATIGINIVANFISPAFDFSNVNP
MAB_2936|M.abscessus_ATCC_1997 IITDPVLIVDKINNTTAAVLGVLTFAIATIGINIVANFVSPAFDFSNLAP
Mflv_3170|M.gilvum_PYR-GCK IIEAPADIVQEVPNTFLLVLAALALLILTIAVNLMANFVAPIYALNNLFP
:* *. * .: .* :*.. :: **.:*::***::* : :.*: *
Mvan_0932|M.vanbaalenii_PYR-1 QRISWRAGGMIAAVGSVLITPWNLYNNPEVIHYTLETLGAFIGPLFGVLI
MSMEG_5730|M.smegmatis_MC2_155 QRISWRAGGMIAAVGSVLITPWNLYNNPEVIHYTLETLGAFIGPLFGVLI
MMAR_1212|M.marinum_M QRISWRTGGMIAAVGSALITPWNLYNHPDVIHYTLETLGAFIGPLFGVLI
MUL_2680|M.ulcerans_Agy99 QRIGWRTGGMIAAVGSALITPWNLYNHPDVIHYTLETLGAFIGPLFGVLI
MAB_2936|M.abscessus_ATCC_1997 TRISWRTGGMIAAVGSILITPWNLYNNPNTIHYTLDALGAVIGPLFGILI
Mflv_3170|M.gilvum_PYR-GCK KHLNFRRAAFISAVIGLVILPWNLYNTPAVINYFLGGLGAILGPLFGIIM
::.:* ..:*:** . :* ****** * .*:* * ***.:*****:::
Mvan_0932|M.vanbaalenii_PYR-1 ADYYLVRKQQVVVDDLFTMEESGKYWYTKGYNRVAVLATAVGAVLAVVPV
MSMEG_5730|M.smegmatis_MC2_155 ADFYLVRKQKVIVDDMFTLDESGKYWYTKGYNKVAVIATVVGAVLAVIPV
MMAR_1212|M.marinum_M ADYYLVRKQHVVVDDLFSLSHDGTYWYRKGYNPAAVIATAVSAAIAMVPV
MUL_2680|M.ulcerans_Agy99 ADYYLVRKQHVVVDDLFSLSHDGTYWYRKGYNPAAVIATAVSAAIAMAPV
MAB_2936|M.abscessus_ATCC_1997 ADFYLVRRRAVVVDDLFTLSPSGTYQYRGGINPIAVTATVLGALLAIATV
Mflv_3170|M.gilvum_PYR-GCK ADYWLVRRSKINVLALFTTDADGEYHYAKGVNVRAVIALVITAVAALLLA
**::***: : * :*: . .* * * * * ** * .: * *: .
Mvan_0932|M.vanbaalenii_PYR-1 LLGGSVAGMATAAQYSWFIGCGVAFAIYYLVA-KRDTLVAASLS------
MSMEG_5730|M.smegmatis_MC2_155 LLGGSVAGMHTAAQYSWFIGCGIAFGLYYVLA-KRDTLVAASVS------
MMAR_1212|M.marinum_M LAS-DVYGMYTAAEYSWFIGCGVALVVYYLLA-TRGRLAIAPPYHPVGAG
MUL_2680|M.ulcerans_Agy99 LAS-DV--------------------------------------------
MAB_2936|M.abscessus_ATCC_1997 IWG-----SPYLATFTWFVGAGIGFAVYLVGM-RYTPRHLIYGR------
Mflv_3170|M.gilvum_PYR-GCK FVP----AFAVVAEFSWFIGAGLGAIVYLVVADRRGPFNDVSGEPIAVDS
:
Mvan_0932|M.vanbaalenii_PYR-1 --
MSMEG_5730|M.smegmatis_MC2_155 --
MMAR_1212|M.marinum_M --
MUL_2680|M.ulcerans_Agy99 --
MAB_2936|M.abscessus_ATCC_1997 --
Mflv_3170|M.gilvum_PYR-GCK TH