For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_3556 (-)

annotation: integral membrane transporter
coordinates: 3616326 - 3617897
length: 523

MASPIALDAHGHTLEPSLYNEDLRPIHPHMRTWTSRVYLTLWVAMCMNPATWTLAASLIALGMNWIQALL
TIVLANLIVLIPMLLNSHAGAKHGISFPVFARAAYGVRGANLPAVMRGLVACGWFGIQTWFGGLGLNLAL
GAAIGPSWSQAEPVDLGFIGTVPITTLVCYAICLVVQVAVIYKGFESLRRFQAIAAPIVVGTVMILIVVL
LFKTGGNLGPVVSQPSHLGWGAHFWLAVFPISLMANIAFWSTLSLNMPDFTRFAENMKAQRRGQSWGLPT
TMLVVSLMAIIATSLAAQHYGVPAGDLWNPDVLVSHFGSRIAVFVGALAIVVSSVQTNMAANLVSPALDF
ANALPKLITFRRGVVVSVALGTLLLPWKLLASPETYVFVWLGFYGGIMGAVGGVLVSDYWLARKTELRVP
ELFTLEGHYHFTRGWNVRAVIATAVGAFVAVGGAYSALGPDGKKTGPFPADGVVPLLRPLYDYNWVVAFL
VAMFVYWLLAAHRRKRHSTVPFDAAPEPATVRS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3556--100% (523)integral membrane transporter
M. smegmatis MC2 155MSMEG_5730-7e-6330.20% (500) permease for cytosine/purines, uracil, thiamine, allantoin
M. smegmatis MC2 155MSMEG_2972-7e-2124.02% (508) permease, cytosine/purines, uracil, thiamine, allantoin family

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_3170-2e-6631.19% (513) permease for cytosine/purines, uracil, thiamine, allantoin
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2936-5e-5631.24% (445) putative cytosine/purine/uracil/thiamine/ allantoin permease
M. marinum MMMAR_1212-5e-6331.20% (516) hypothetical protein MMAR_1212
M. avium 104-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_2680-4e-6031.75% (463) hypothetical protein MUL_2680
M. vanbaalenii PYR-1Mvan_0932-8e-6430.88% (489) permease for cytosine/purines, uracil, thiamine, allantoin

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1212|M.marinum_M               MIDTT-APHSP-------------VHSPSHGAGPANIKP-----------
MUL_2680|M.ulcerans_Agy99           MIDTT-APHSP-------------VHSPSHGAGPANIKP-----------
Mvan_0932|M.vanbaalenii_PYR-1       MTDTAPAPPSRKLPPGAVVGADDLVEAAGHPVGAGRIEP-----------
MAB_2936|M.abscessus_ATCC_1997      MSGVLTADAVAP-------------TGGHSAAGDSVIKP-----------
Mflv_3170|M.gilvum_PYR-GCK          MSVCALLSKLVEYYFRKVEFSGDARVGAPTVTGVSMSTESTGLIGDSSRN
MSMEG_3556|M.smegmatis_MC2_155      --------------------------MASPIALDAHGHT-----------
                                                                   .  .               

MMAR_1212|M.marinum_M               ------DYHPRLTNDDLAPLR--EQTWGTYNIFAFWMSDVHSVGGYVTAG
MUL_2680|M.ulcerans_Agy99           ------DYHPRLTNDDLAPLR--EQTWGTYNIFAFWMSDVHSVGGYVTAG
Mvan_0932|M.vanbaalenii_PYR-1       ------GYDPRLTNEDLAPLR--KQTWTSYNIFAFWMSDVHSVGGYVTAG
MAB_2936|M.abscessus_ATCC_1997      ------GYDPALTNGDLAPLR--TQTWTSYNFFAFWMSDVHSVGGYVFAG
Mflv_3170|M.gilvum_PYR-GCK          DHTALAGVSPHLYNPDLAPTKRAGRRWGSYNIFTLWANDVHSLGNYSFAI
MSMEG_3556|M.smegmatis_MC2_155      -------LEPSLYNEDLRPIHPHMRTWTSRVYLTLWVAMCMNPATWTLAA
                                             * * * ** * :   : * :   :::*     . . :  * 

MMAR_1212|M.marinum_M               SLFALGLASWQVLVSLVIAITIVYFLCNLVARPSQATGVPYPVICRTAFG
MUL_2680|M.ulcerans_Agy99           SLFALGLASWQVLVSLVIAITIVYFLCNLVARPSQATGVPYPVICRTAFG
Mvan_0932|M.vanbaalenii_PYR-1       SLFALGLASWQVLVALLAGITIVYYLCNLVAKPSQATGVPYPVICRTVFG
MAB_2936|M.abscessus_ATCC_1997      SLFALGISASQVLLALLVGIAAVYWLCNLVARPSQQTGVPYPVTARIAFG
Mflv_3170|M.gilvum_PYR-GCK          GLFALGLGGWQILLALGLGGVFLFLLLNLSGFMGEKTGVPFPVMSRIAFG
MSMEG_3556|M.smegmatis_MC2_155      SLIALGMNWIQALLTIVLANLIVLIPMLLNSHAGAKHGISFPVFARAAYG
                                    .*:***:   * *:::  .   :     * .  .   *:.:** .* .:*

MMAR_1212|M.marinum_M               VLGANIPAIIRGLIAVAWYGIQTYLASAALDVVMIKLFPGLARYAVVEDY
MUL_2680|M.ulcerans_Agy99           VLGANIPAIIRGLIAVAWYGIQTYLASAALDVVMIKLFPGLARYAVVEDY
Mvan_0932|M.vanbaalenii_PYR-1       VLGANIPAIIRGLIAVAWYGIQTFLASAALDIVLIKLFPALAPYAVVEDF
MAB_2936|M.abscessus_ATCC_1997      VRGANLPAVIRGLIAVAWYGIQTYLASTAFVLLAVKFQPSLGRYGNAGEY
Mflv_3170|M.gilvum_PYR-GCK          IRGAQIPALIRGAVAIAWFGIQTYLASVVLRIMIIALAPSAES---LDSN
MSMEG_3556|M.smegmatis_MC2_155      VRGANLPAVMRGLVACGWFGIQTWFGGLGLNLALGAAIGPSWSQAEPVDL
                                    : **::**::** :* .*:****::..  : :                . 

MMAR_1212|M.marinum_M               GFLG-LPALGWASYLILWVLQACVFWRGMEAIRKFIDFCGPAVY-VVMFA
MUL_2680|M.ulcerans_Agy99           GFLG-LPALGWASYLILWVLQACVFWRGMEAIRKFIDFCGPAVY-VVIFA
Mvan_0932|M.vanbaalenii_PYR-1       GFAG-LSLLGWCSFLLLWVLQACVFWRGMESIRKFIDFCGPAVY-VVMFL
MAB_2936|M.abscessus_ATCC_1997      GFLG-LSLLGWGGFLLMWVLQAAVFWNGMEAIRKFIDFCGPAVY-AVMLA
Mflv_3170|M.gilvum_PYR-GCK          SVLG-LSTLGWISFVVLWVVRVIIVSYGMEMIRRYEAFAGPVIL-VTMIA
MSMEG_3556|M.smegmatis_MC2_155      GFIGTVPITTLVCYAICLVVQVAVIYKGFESLRRFQAIAAPIVVGTVMIL
                                    .. * :.      : :  *::. :.  *:* :*::  :..* :  ..:: 

MMAR_1212|M.marinum_M               LSGYLISKAGWAAIDLNLG-DVRYSGWDAIPVMLGAIALVVSYFSGPMLN
MUL_2680|M.ulcerans_Agy99           LSGYLISTAGWAAIDLNLG-DVRYSGWDAIPVMLGAIALVVSYFSGPMLN
Mvan_0932|M.vanbaalenii_PYR-1       LCGYLISEAGWGAIDLNLG-DVTYTGWSSVPVMLGAIALVVSYFSGPMLN
MAB_2936|M.abscessus_ATCC_1997      LALYLVVAAGWENVHFGLASGPPKSGFAALATILSAIALVVSYFSGPMLN
Mflv_3170|M.gilvum_PYR-GCK          LAVWMLNNADWS-IAWSTP--DSLTGVDMWLKIIGGASLWVAIYGTFVLN
MSMEG_3556|M.smegmatis_MC2_155      IVVLLFKTGGNLGPVVSQPSHLGWGAHFWLAVFPISLMANIAFWSTLSLN
                                    :   :.  ..      .        .      :  .    :: :.   **

MMAR_1212|M.marinum_M               FGDFSRYGRSFGAVRKGNFLGLPLNFLLFSLLVVVTASLTVPVFG-----
MUL_2680|M.ulcerans_Agy99           FGDFSRYGRSFGAVRKGNFLGLPLNFLLFSLLVVVTASLTVPVFG-----
Mvan_0932|M.vanbaalenii_PYR-1       FGDFSRYGKSFEAVKKGNFLGLPVNFLLFSVLVVVTASLTLPVFG-----
MAB_2936|M.abscessus_ATCC_1997      FGDFSRYGRTFGEVKRGNFLGLPLNFLFFAVLAVCTVSAGATVIGRGEDG
Mflv_3170|M.gilvum_PYR-GCK          FCDFTRNATSKRAIVHGNFWGIPLNMLVFGGIVITLAGAQFRIDG-----
MSMEG_3556|M.smegmatis_MC2_155      MPDFTRFAENMKAQRRGQSWGLPTTMLVVSLMAIIATSLAAQHYG--VPA
                                    : **:* . .     :*:  *:* .:*... :.:  ..      *     

MMAR_1212|M.marinum_M               ELITDPVQTVARIDSTFAIILGASTFTIATIGINIVANFISPAFDFSNVN
MUL_2680|M.ulcerans_Agy99           ELITDPVQTVARIDSTFAIILGASTFTIATIGINIVANFISPAFDFSNVN
Mvan_0932|M.vanbaalenii_PYR-1       ELITDPVETVARIDSTFAIVLGALTFATATIGINIVANFISPAFDFSNVS
MAB_2936|M.abscessus_ATCC_1997      AIITDPVLIVDKINNTTAAVLGVLTFAIATIGINIVANFVSPAFDFSNLA
Mflv_3170|M.gilvum_PYR-GCK          RIIEAPADIVQEVPNTFLLVLAALALLILTIAVNLMANFVAPIYALNNLF
MSMEG_3556|M.smegmatis_MC2_155      GDLWNPDVLVSHFGSRIAVFVGALAIVVSSVQTNMAANLVSPALDFANAL
                                      :  *   * .. .    .:.. ::   ::  *: **:::*   : *  

MMAR_1212|M.marinum_M               PQRISWRTGGMIAAVGSALITPWNLYNHPD-VIHYTLETLGAFIGPLFGV
MUL_2680|M.ulcerans_Agy99           PQRIGWRTGGMIAAVGSALITPWNLYNHPD-VIHYTLETLGAFIGPLFGV
Mvan_0932|M.vanbaalenii_PYR-1       PQRISWRAGGMIAAVGSVLITPWNLYNNPE-VIHYTLETLGAFIGPLFGV
MAB_2936|M.abscessus_ATCC_1997      PTRISWRTGGMIAAVGSILITPWNLYNNPN-TIHYTLDALGAVIGPLFGI
Mflv_3170|M.gilvum_PYR-GCK          PKHLNFRRAAFISAVIGLVILPWNLYNTPA-VINYFLGGLGAILGPLFGI
MSMEG_3556|M.smegmatis_MC2_155      PKLITFRRGVVVSVALGTLLLPWKLLASPETYVFVWLGFYGGIMGAVGGV
                                    *  : :* . .::.. . :: **:*   *   :   *   *..:*.: *:

MMAR_1212|M.marinum_M               LIADYYLVRKQHVVVDDLFSLSHDGTYWYRKGYNPAAVIATAVSAAIAMV
MUL_2680|M.ulcerans_Agy99           LIADYYLVRKQHVVVDDLFSLSHDGTYWYRKGYNPAAVIATAVSAAIAMA
Mvan_0932|M.vanbaalenii_PYR-1       LIADYYLVRKQQVVVDDLFTMEESGKYWYTKGYNRVAVLATAVGAVLAVV
MAB_2936|M.abscessus_ATCC_1997      LIADFYLVRRRAVVVDDLFTLSPSGTYQYRGGINPIAVTATVLGALLAIA
Mflv_3170|M.gilvum_PYR-GCK          IMADYWLVRRSKINVLALFTTDADGEYHYAKGVNVRAVIALVITAVAALL
MSMEG_3556|M.smegmatis_MC2_155      LVSDYWLARKTELRVPELFTLEG--HYHFTRGWNVRAVIATAVGAFVAVG
                                    :::*::*.*:  : *  **: .    * :  * *  ** * .: *  *: 

MMAR_1212|M.marinum_M               PVLAS---------------DVYGMYTAAEYSWFIGCGVALVVYYLLA-T
MUL_2680|M.ulcerans_Agy99           PVLAS---------------DV----------------------------
Mvan_0932|M.vanbaalenii_PYR-1       PVLLGG--------------SVAGMATAAQYSWFIGCGVAFAIYYLVA-K
MAB_2936|M.abscessus_ATCC_1997      TVIWG-------------------SPYLATFTWFVGAGIGFAVYLVGM-R
Mflv_3170|M.gilvum_PYR-GCK          LAFVP------------------AFAVVAEFSWFIGAGLGAIVYLVVADR
MSMEG_3556|M.smegmatis_MC2_155      GAYSALGPDGKKTGPFPADGVVPLLRPLYDYNWVVAFLVAMFVYWLLAAH
                                     .                                                

MMAR_1212|M.marinum_M               RGRLAIAPPYHPVGAG-----
MUL_2680|M.ulcerans_Agy99           ---------------------
Mvan_0932|M.vanbaalenii_PYR-1       RDTLVAASLS-----------
MAB_2936|M.abscessus_ATCC_1997      YTPRHLIYGR-----------
Mflv_3170|M.gilvum_PYR-GCK          RGPFNDVSGEPIAVDSTH---
MSMEG_3556|M.smegmatis_MC2_155      RRKRHSTVPFDAAPEPATVRS