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VSVCALLSKLVEYYFRKVEFSGDARVGAPTVTGVSMSTESTGLIGDSSRNDHTALAGVSPHLYNPDLAPT KRAGRRWGSYNIFTLWANDVHSLGNYSFAIGLFALGLGGWQILLALGLGGVFLFLLLNLSGFMGEKTGVP FPVMSRIAFGIRGAQIPALIRGAVAIAWFGIQTYLASVVLRIMIIALAPSAESLDSNSVLGLSTLGWISF VVLWVVRVIIVSYGMEMIRRYEAFAGPVILVTMIALAVWMLNNADWSIAWSTPDSLTGVDMWLKIIGGAS LWVAIYGTFVLNFCDFTRNATSKRAIVHGNFWGIPLNMLVFGGIVITLAGAQFRIDGRIIEAPADIVQEV PNTFLLVLAALALLILTIAVNLMANFVAPIYALNNLFPKHLNFRRAAFISAVIGLVILPWNLYNTPAVIN YFLGGLGAILGPLFGIIMADYWLVRRSKINVLALFTTDADGEYHYAKGVNVRAVIALVITAVAALLLAFV PAFAVVAEFSWFIGAGLGAIVYLVVADRRGPFNDVSGEPIAVDSTH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3170 | - | - | 100% (536) | permease for cytosine/purines, uracil, thiamine, allantoin |
| M. gilvum PYR-GCK | Mflv_0055 | - | 2e-19 | 23.64% (423) | permease for cytosine/purines, uracil, thiamine, allantoin |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2815c | - | 1e-109 | 42.39% (460) | NCS1 nucleoside transporter family protein |
| M. marinum M | MMAR_1212 | - | 1e-103 | 41.76% (467) | hypothetical protein MMAR_1212 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5730 | - | 1e-105 | 42.46% (471) | permease for cytosine/purines, uracil, thiamine, allantoin |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2680 | - | 3e-96 | 41.76% (431) | hypothetical protein MUL_2680 |
| M. vanbaalenii PYR-1 | Mvan_0932 | - | 1e-104 | 42.04% (471) | permease for cytosine/purines, uracil, thiamine, allantoin |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5730|M.smegmatis_MC2_155 ---------MTETA-VPNAGGGPAGPDGSFPVAAGDLVEAAGHPIGSGAI
Mvan_0932|M.vanbaalenii_PYR-1 ---------MTDTAPAPPSRKLPPG----AVVGADDLVEAAGHPVGAGRI
MMAR_1212|M.marinum_M ---------MIDTT-APHSP-----------------VHSPSHGAGPANI
MUL_2680|M.ulcerans_Agy99 ---------MIDTT-APHSP-----------------VHSPSHGAGPANI
Mflv_3170|M.gilvum_PYR-GCK MSVCALLSKLVEYYFRKVEFSGDARVGAPTVTGVSMSTESTGLIGDSSRN
MAB_2815c|M.abscessus_ATCC_199 -----------------------------------MVLEAAGPAAG----
.:.. .
MSMEG_5730|M.smegmatis_MC2_155 KP----GYDPRLTNEDLAPLRQQ--KWGSYNIFAFWMSDVHSVGGYVTAG
Mvan_0932|M.vanbaalenii_PYR-1 EP----GYDPRLTNEDLAPLRKQ--TWTSYNIFAFWMSDVHSVGGYVTAG
MMAR_1212|M.marinum_M KP----DYHPRLTNDDLAPLREQ--TWGTYNIFAFWMSDVHSVGGYVTAG
MUL_2680|M.ulcerans_Agy99 KP----DYHPRLTNDDLAPLREQ--TWGTYNIFAFWMSDVHSVGGYVTAG
Mflv_3170|M.gilvum_PYR-GCK DHTALAGVSPHLYNPDLAPTKRAGRRWGSYNIFTLWANDVHSLGNYSFAI
MAB_2815c|M.abscessus_ATCC_199 ----------RLSNDDLAPTTAAQATWRTWDIFCLWMTSAHSLGSYGFAV
:* * **** * :::** :* ...**:*.* *
MSMEG_5730|M.smegmatis_MC2_155 SLFALGLASWQVLVALLIGISIVNVFCNLVAKPSQQTGVPYPVICRTVFG
Mvan_0932|M.vanbaalenii_PYR-1 SLFALGLASWQVLVALLAGITIVYYLCNLVAKPSQATGVPYPVICRTVFG
MMAR_1212|M.marinum_M SLFALGLASWQVLVSLVIAITIVYFLCNLVARPSQATGVPYPVICRTAFG
MUL_2680|M.ulcerans_Agy99 SLFALGLASWQVLVSLVIAITIVYFLCNLVARPSQATGVPYPVICRTAFG
Mflv_3170|M.gilvum_PYR-GCK GLFALGLGGWQILLALGLGGVFLFLLLNLSGFMGEKTGVPFPVMSRIAFG
MAB_2815c|M.abscessus_ATCC_199 GMLALGLTGWQTMLALFTGVLVLWTGSNLIGIAGQRLGVPFPVFARATFG
.::**** .** :::* . .: ** . .: ***:**:.* .**
MSMEG_5730|M.smegmatis_MC2_155 VLGANIPAIIRGLIAVAWYGIQTFLASAALDIVLVKLFPALAPYAVVDDY
Mvan_0932|M.vanbaalenii_PYR-1 VLGANIPAIIRGLIAVAWYGIQTFLASAALDIVLIKLFPALAPYAVVEDF
MMAR_1212|M.marinum_M VLGANIPAIIRGLIAVAWYGIQTYLASAALDVVMIKLFPGLARYAVVEDY
MUL_2680|M.ulcerans_Agy99 VLGANIPAIIRGLIAVAWYGIQTYLASAALDVVMIKLFPGLARYAVVEDY
Mflv_3170|M.gilvum_PYR-GCK IRGAQIPALIRGAVAIAWFGIQTYLASVVLRIMIIALAPSAES---LDSN
MAB_2815c|M.abscessus_ATCC_199 VFGANIPALLRGLVAIFWYGIQTYLASTAVIVLLLRLDPGLRS---WTEP
: **:***::** :*: *:****:***..: :::: * *. .
MSMEG_5730|M.smegmatis_MC2_155 GFAGLSLLGWGSFLLLWVLQACVFWRGMESIRKFIDFCGPAVYVVMFLLC
Mvan_0932|M.vanbaalenii_PYR-1 GFAGLSLLGWCSFLLLWVLQACVFWRGMESIRKFIDFCGPAVYVVMFLLC
MMAR_1212|M.marinum_M GFLGLPALGWASYLILWVLQACVFWRGMEAIRKFIDFCGPAVYVVMFALS
MUL_2680|M.ulcerans_Agy99 GFLGLPALGWASYLILWVLQACVFWRGMEAIRKFIDFCGPAVYVVIFALS
Mflv_3170|M.gilvum_PYR-GCK SVLGLSTLGWISFVVLWVVRVIIVSYGMEMIRRYEAFAGPVILVTMIALA
MAB_2815c|M.abscessus_ATCC_199 TFLGLHALGWAAFLSLWTVQLLILNYGMEVVRKASDVAGPVVWIGMLALA
. ** *** ::: **.:: :. *** :*: ..**.: : :: *.
MSMEG_5730|M.smegmatis_MC2_155 GYLIFQAGWGAIDLSLGEVTYTGWSSVPVMLGAIALVVSYFSGPMLNFGD
Mvan_0932|M.vanbaalenii_PYR-1 GYLISEAGWGAIDLNLGDVTYTGWSSVPVMLGAIALVVSYFSGPMLNFGD
MMAR_1212|M.marinum_M GYLISKAGWAAIDLNLGDVRYSGWDAIPVMLGAIALVVSYFSGPMLNFGD
MUL_2680|M.ulcerans_Agy99 GYLISTAGWAAIDLNLGDVRYSGWDAIPVMLGAIALVVSYFSGPMLNFGD
Mflv_3170|M.gilvum_PYR-GCK VWMLNNADWSIAWS--TPDSLTGVDMWLKIIGGASLWVAIYGTFVLNFCD
MAB_2815c|M.abscessus_ATCC_199 VWMLDSVGWSIDFGARTGAPLSAGATVLAFVGVAFLMVAFMAGPLVNYAD
::: ..*. :. ::* * *: . ::*: *
MSMEG_5730|M.smegmatis_MC2_155 FSRYGRTFAAVKKGNFLGLPVNFLVFSVLVVVTASLTLPVFGELITDPVE
Mvan_0932|M.vanbaalenii_PYR-1 FSRYGKSFEAVKKGNFLGLPVNFLLFSVLVVVTASLTLPVFGELITDPVE
MMAR_1212|M.marinum_M FSRYGRSFGAVRKGNFLGLPLNFLLFSLLVVVTASLTVPVFGELITDPVQ
MUL_2680|M.ulcerans_Agy99 FSRYGRSFGAVRKGNFLGLPLNFLLFSLLVVVTASLTVPVFGELITDPVQ
Mflv_3170|M.gilvum_PYR-GCK FTRNATSKRAIVHGNFWGIPLNMLVFGGIVITLAGAQFRIDGRIIEAPAD
MAB_2815c|M.abscessus_ATCC_199 FARFAPSRRAILRGNALGIPFNETAFVVISIVISLAALKKYGSAMTDPVE
*:* . : *: :** *:*.* * : :. : . * : *.:
MSMEG_5730|M.smegmatis_MC2_155 TVARIDSTFAIVLGALTFAIATIGINIVANFISPAFDFSNVSPQRISWRA
Mvan_0932|M.vanbaalenii_PYR-1 TVARIDSTFAIVLGALTFATATIGINIVANFISPAFDFSNVSPQRISWRA
MMAR_1212|M.marinum_M TVARIDSTFAIILGASTFTIATIGINIVANFISPAFDFSNVNPQRISWRT
MUL_2680|M.ulcerans_Agy99 TVARIDSTFAIILGASTFTIATIGINIVANFISPAFDFSNVNPQRIGWRT
Mflv_3170|M.gilvum_PYR-GCK IVQEVPNTFLLVLAALALLILTIAVNLMANFVAPIYALNNLFPKHLNFRR
MAB_2815c|M.abscessus_ATCC_199 LVADIDSDAVVVVAAVLFAIATVGINVVLNFVSPSYDISNVAPKYISFRT
* : . :::.* : *:.:*:: **::* : :.*: *: :.:*
MSMEG_5730|M.smegmatis_MC2_155 GGMIAAVGSVLITPWNLYNNPEVIHYTLETLGAFIGPLFGVLIADFYLVR
Mvan_0932|M.vanbaalenii_PYR-1 GGMIAAVGSVLITPWNLYNNPEVIHYTLETLGAFIGPLFGVLIADYYLVR
MMAR_1212|M.marinum_M GGMIAAVGSALITPWNLYNHPDVIHYTLETLGAFIGPLFGVLIADYYLVR
MUL_2680|M.ulcerans_Agy99 GGMIAAVGSALITPWNLYNHPDVIHYTLETLGAFIGPLFGVLIADYYLVR
Mflv_3170|M.gilvum_PYR-GCK AAFISAVIGLVILPWNLYNTPAVINYFLGGLGAILGPLFGIIMADYWLVR
MAB_2815c|M.abscessus_ATCC_199 GGIITAVLSVAVLPWKIWGNEAAIVYFLGGVGALMGPVFGILVVDYYLLR
..:*:** . : **:::. .* * * :**::**:**:::.*::*:*
MSMEG_5730|M.smegmatis_MC2_155 KQKVIVDDMFTLDESGKYWYTKGYNKVAVIATVVGAVLAVIPVLLGGSVA
Mvan_0932|M.vanbaalenii_PYR-1 KQQVVVDDLFTMEESGKYWYTKGYNRVAVLATAVGAVLAVVPVLLGGSVA
MMAR_1212|M.marinum_M KQHVVVDDLFSLSHDGTYWYRKGYNPAAVIATAVSAAIAMVPVLAS-DVY
MUL_2680|M.ulcerans_Agy99 KQHVVVDDLFSLSHDGTYWYRKGYNPAAVIATAVSAAIAMAPVLAS-DV-
Mflv_3170|M.gilvum_PYR-GCK RSKINVLALFTTDADGEYHYAKGVNVRAVIALVITAVAALLLAFVP----
MAB_2815c|M.abscessus_ATCC_199 RQHTHTADLYSESPGGAYHYAGGFNPAALISLGIGGIVAVVIALVP----
:.: . ::: . .* * * * * *::: : . *: .:
MSMEG_5730|M.smegmatis_MC2_155 GMHTAAQYSWFIGCGIAFGLYYVLAKRDTLVAASVS---------
Mvan_0932|M.vanbaalenii_PYR-1 GMATAAQYSWFIGCGVAFAIYYLVAKRDTLVAASLS---------
MMAR_1212|M.marinum_M GMYTAAEYSWFIGCGVALVVYYLLATRGRLAIAPPYHPVGAG---
MUL_2680|M.ulcerans_Agy99 ---------------------------------------------
Mflv_3170|M.gilvum_PYR-GCK AFAVVAEFSWFIGAGLGAIVYLVVADRRGPFNDVSGEPIAVDSTH
MAB_2815c|M.abscessus_ATCC_199 RAQGVTALSWPVGALLGGVLMYLLGRGRSRSSRVGPA--------