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MPSSNRWLPPLDEESPRAERTGSARGAGPTAEPGAGERVTVTRAAAARSREMGSRMYGLVHRAATADGAD KSGLTALTWPVVANFAVDAAMAVALANTLFFAAASGESKSRVALYLLITIAPFAVIAPLIGPALDRLQHG RRVALAASFALRTVLIVVLIANYDGATGNFPSWVLYPCALGMMVLSKSFSVLRSAVTPRVLPPTIDLVRV NSRLTTFGLLGGTVAGGGVAAGAEYLFGLVHLPGALYVIVAVSVAGAVLSMRIPKWVEVTEGEVPTTLSY HGGPGELRRPEHPDTTGKPDKPQSVRQPMGRNTITALWGNCTIKVMVGFLFLYPAFVAKSHDASGWEQLL ILGIIGAAAGIGNFAGNMTAARLKLGHPAQMVVRLAIVVTVFALLAALTGKLLVAALATLVTSGASAIAK ASLDASLQDDLPEASRASAFGRSESVLQLAWVAGGAIGVLIYTDLSVGFTTITAVLILGLAQTIVSYRGE SLIPGFGGNRPVLAEREGTMAWGAR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_5693 | - | - | 100% (515) | transporter, major facilitator family protein |
M. smegmatis MC2 155 | MSMEG_0357 | - | 7e-07 | 23.70% (384) | transmembrane transport protein |
M. smegmatis MC2 155 | MSMEG_6922 | - | 2e-06 | 23.83% (386) | transporter, major facilitator family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0900c | - | 0.0 | 75.00% (512) | transmembrane protein |
M. gilvum PYR-GCK | Mflv_1711 | - | 0.0 | 80.04% (506) | major facilitator transporter |
M. tuberculosis H37Rv | Rv0876c | - | 0.0 | 75.00% (512) | transmembrane protein |
M. leprae Br4923 | MLBr_02143 | - | 0.0 | 71.46% (508) | hypothetical protein MLBr_02143 |
M. abscessus ATCC 19977 | MAB_0875c | - | 0.0 | 73.97% (511) | hypothetical protein MAB_0875c |
M. marinum M | MMAR_4656 | - | 0.0 | 74.90% (514) | transmembrane protein |
M. avium 104 | MAV_1005 | - | 0.0 | 73.92% (510) | hypothetical protein MAV_1005 |
M. thermoresistible (build 8) | TH_1066 | - | 0.0 | 81.57% (510) | POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN |
M. ulcerans Agy99 | MUL_0274 | - | 0.0 | 74.71% (514) | transmembrane protein |
M. vanbaalenii PYR-1 | Mvan_5040 | - | 0.0 | 81.42% (506) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_1711|M.gilvum_PYR-GCK ----------------------------------MANYPSDPQTRPGNRR Mvan_5040|M.vanbaalenii_PYR-1 ---MTGSRRDHRDPDGQQGGRYYPPRPPAGEHPGMANYPSDPAMSPGNRR MSMEG_5693|M.smegmatis_MC2_155 -------------------------------------------------- TH_1066|M.thermoresistible__bu ----------------------------------MANYPSD---DPAPRR Mb0900c|M.bovis_AF2122/97 --------------MAPTPGRR-TRNGSVNGHPGMANYPPG---DANYRR Rv0876c|M.tuberculosis_H37Rv --------------MAPTPGRR-TRNGSVNGHPGMANYPPD---DANYRR MMAR_4656|M.marinum_M ---MSGWRRDHQGRMAASPGRR-TRNGSVSEHPGMANYPTD---GPGNRR MUL_0274|M.ulcerans_Agy99 ---MSGWRRDHQGRMAASPGRR-TRNGSVSEHPGMANYPTD---GPGNRR MLBr_02143|M.leprae_Br4923 ---MSGRRRNHPGRLASIPGLR-TRTGSRNQHPGIANYPAD---SSDFRP MAV_1005|M.avium_104 ---MSGRRQGDPGRVAAKPGRR-PGNSAAAPHPGAANYPAG---DTGDRR MAB_0875c|M.abscessus_ATCC_199 MRDDYARFGNRHGSSDSPSRRRNQDPRDANSHPGMANYPTG----SAPRE Mflv_1711|M.gilvum_PYR-GCK P------------------GRPYSPGQAGNRWLPPLDDDPRRAGR---DY Mvan_5040|M.vanbaalenii_PYR-1 S------------------GRPGPSSQSANRWLPPLDDSSRPHGH---SY MSMEG_5693|M.smegmatis_MC2_155 -------------------------MPSSNRWLPPLDEESPRAER---TG TH_1066|M.thermoresistible__bu P------------------GRPKAP-PSANRWLPPLDEDRPTFDRGAGEP Mb0900c|M.bovis_AF2122/97 S-------------------RRPPPMPSANRYLPPLGEQ-PEPE-----R Rv0876c|M.tuberculosis_H37Rv S-------------------RRPPPMPSANRYLPPLGEQ-PEPE-----R MMAR_4656|M.marinum_M T-------------------RRPPPMPSANRYLPPLDRE-PESEDDA-EG MUL_0274|M.ulcerans_Agy99 T-------------------RRPPPMPSANRYLPPLDRE-PESEDDA-EG MLBr_02143|M.leprae_Br4923 AQQRRALEQREQQAGQLDPARRSPSMPSANRYLPPLGQQQSEPQ-----H MAV_1005|M.avium_104 T-------------------RRPPPMPSANRYLPPLGHQ-PQPD----RG MAB_0875c|M.abscessus_ATCC_199 R---------------------LRASSSSNRYLPPLGEERRERVR----- :.**:****. . Mflv_1711|M.gilvum_PYR-GCK DSRYHDAPSAA-GGEKVTVTRAAAQRSREMGSKVYGMVHRAATADGADKS Mvan_5040|M.vanbaalenii_PYR-1 PP----PPGRG-ADEKVTVTRAAAQRSREMGSKMYGLVHRAATADGADKS MSMEG_5693|M.smegmatis_MC2_155 SARGAGPTAEPGAGERVTVTRAAAARSREMGSRMYGLVHRAATADGADKS TH_1066|M.thermoresistible__bu PPRGYRSTGRPRSDERITVTRAAAQRSREMGSRMYGLVHRAATADGADKS Mb0900c|M.bovis_AF2122/97 SRVPPRTTR---AGERITVTRAAAMRSREMGSRMYLLVHRAATADGADKS Rv0876c|M.tuberculosis_H37Rv SRVPPRTTR---AGERITVTRAAAMRSREMGSRMYLLVHRAATADGADKS MMAR_4656|M.marinum_M NEAPPPSPRGLSSGERITVTRAAAMRSREMGSRMYWMVQRAATADGADKS MUL_0274|M.ulcerans_Agy99 NEAPPPPPRGLSSGERITVTRAAAMRSREMGSRMYWMVQRAATADGADKS MLBr_02143|M.leprae_Br4923 NSAPPCGPY---PGERIKVTRAAAQRSREMGYRMYWMVQRAATADGADKS MAV_1005|M.avium_104 AGAPPRGPV---AGERITVTRAAALRSREMGSRMYWMVQRAATADGADKS MAB_0875c|M.abscessus_ATCC_199 ----RRPPPEQDHPQKLTVTRVAAMRSREMGSRMYGLFQKAATADGADKS . :::.***.** ****** ::* :.::********** Mflv_1711|M.gilvum_PYR-GCK GLTALTWPVVANFAVDAAMAVALANTLFFAAASGESKGKVALYLLITIAP Mvan_5040|M.vanbaalenii_PYR-1 GLTALTWPVVANFAVDAAMAVALANTLFFAAASGESKSRVALYLLITIAP MSMEG_5693|M.smegmatis_MC2_155 GLTALTWPVVANFAVDAAMAVALANTLFFAAASGESKSRVALYLLITIAP TH_1066|M.thermoresistible__bu GLTALTWPVVANFAVDAAMAVALANTLFFAAATGESKARVALYLLITIAP Mb0900c|M.bovis_AF2122/97 GLTALTWPVMANFAVDSAMAVALANTLFFAAASGESKSRVALYLLITIAP Rv0876c|M.tuberculosis_H37Rv GLTALTWPVMANFAVDSAMAVALANTLFFAAASGESKSRVALYLLITIAP MMAR_4656|M.marinum_M GLTALTWPTMANFAVDSSMAVALANTLFFAAASGESKSKVALYLLITIAP MUL_0274|M.ulcerans_Agy99 GLTALTWPTMANFAVDSSMAVALANTLFFAAASGESKSKVALYLLITIAP MLBr_02143|M.leprae_Br4923 GLTALTWPVVTNFAVDSAMAVALANTLFFAAASGESKSKVALYLLITIAP MAV_1005|M.avium_104 GLTALTWPVVANFAVDAAMAVALANTLFFAAATGESKGRVALYLLITIAP MAB_0875c|M.abscessus_ATCC_199 GLTALTYPVMANFAVDAAMAVALANTLFFAAATAESKSKVALYLLITIAP ******:*.::*****::**************:.***.:*********** Mflv_1711|M.gilvum_PYR-GCK FAVIAPLIGPALDRLQHGRRVALAASFVLRTVLAVVLIANFDSATGSFPS Mvan_5040|M.vanbaalenii_PYR-1 FAVIAPLIGPALDRLQHGRRVALAASFSLRTVLAVVLIANFDSATGSFPS MSMEG_5693|M.smegmatis_MC2_155 FAVIAPLIGPALDRLQHGRRVALAASFALRTVLIVVLIANYDGATGNFPS TH_1066|M.thermoresistible__bu FAVIAPLIGPALDRLQHGRRVALATSFGLRTALVVVLIANYDGATGSFPS Mb0900c|M.bovis_AF2122/97 FAVIAPLIGPALDRLQHGRRVALALSFGLRTALAVVLIMNYDGATGSFPS Rv0876c|M.tuberculosis_H37Rv FAVIAPLIGPALDRLQHGRRVALALSFGLRTALAVVLIMNYDGATGSFPS MMAR_4656|M.marinum_M FAVVAPLIGPALDKLQHGRRVALALSFGLRTVLALVLIMNYDGASGSFPS MUL_0274|M.ulcerans_Agy99 FAVVAPLIGPALDKLQHGRRVALALSFGLRTVLALVLIMNYDGASGSFPS MLBr_02143|M.leprae_Br4923 FAVIAPLIGPALDRLQHGRRVALATSFVLRTGLATLLIMNYDGATGSYPS MAV_1005|M.avium_104 FAVIAPLIGPALDRLQHGRRVALAASFVLRTALAAVLIMNYDGASGSYPS MAB_0875c|M.abscessus_ATCC_199 FAVIAPLIGPALDRLQHGRRAALAASFGLRTLLAVIMIANYDGASGSFPP ***:*********:******.*** ** *** * ::* *:*.*:*.:*. Mflv_1711|M.gilvum_PYR-GCK WVLYPCALGMMVLSKSFSVLRSAVTPRVLPPSIDLVRVNSRLTTFGLLGG Mvan_5040|M.vanbaalenii_PYR-1 WVLYPCALGMMVLSKSFSVLRSAVTPRVLPPTIDLVRVNSRLTTFGLLGG MSMEG_5693|M.smegmatis_MC2_155 WVLYPCALGMMVLSKSFSVLRSAVTPRVLPPTIDLVRVNSRLTTFGLLGG TH_1066|M.thermoresistible__bu WVLYPCALAMMVLSKSFSVLRSAMTPRVLPPTIDLVRVNSRLTMFGLLGG Mb0900c|M.bovis_AF2122/97 WVLYPCALAMMVFSKSFSVLRSAVTPRVMPPTIDLVRVNSRLTVFGLLGG Rv0876c|M.tuberculosis_H37Rv WVLYPCALAMMVFSKSFSVLRSAVTPRVMPPTIDLVRVNSRLTVFGLLGG MMAR_4656|M.marinum_M WVLYPCALAMMVLSKSFSVLRSAMTPRVMPPSIDLVRVNSRLTVFGLLGG MUL_0274|M.ulcerans_Agy99 WVLYPCALAMMVLSKSFSVLRSAMTPRVMPPSIDLVRVNSRLTVFGLLGG MLBr_02143|M.leprae_Br4923 MVLYPCALAMMVLSKSFSVLRSAVTPRVMPPSIDLVRVNSRLTVFGLLGG MAV_1005|M.avium_104 MVLYPCALAMMVLSKSFSVLRSAVTPRVMPPSIDLVRVNSRLTMFGLLGG MAB_0875c|M.abscessus_ATCC_199 WVLYPCALSMLVLSKSFGVLRGAVTPRVLPPTIDLVRVNSRLTTFGLVGG *******.*:*:****.***.*:****:**:*********** ***:** Mflv_1711|M.gilvum_PYR-GCK TMIGGGIAAAAEYGFQ-LFQMPGALYVVVAVTVAGAVLAMRIPKWVEVTE Mvan_5040|M.vanbaalenii_PYR-1 TMIGGGIAAAAEWGFQ-LFQMPGALYVVVAVTIGGAVLAMRIPKWVEVTA MSMEG_5693|M.smegmatis_MC2_155 TVAGGGVAAGAEYLFG-LVHLPGALYVIVAVSVAGAVLSMRIPKWVEVTE TH_1066|M.thermoresistible__bu TMLGGAVAAAAEYVFN-LFELPGALYVIVAVSLAGAVLSMRIPRWVEVTE Mb0900c|M.bovis_AF2122/97 TIAGGAIAAGVEFVCTHLFQLPGALFVVVAITIAGASLSMRIPRWVEVTS Rv0876c|M.tuberculosis_H37Rv TIAGGAIAAGVEFVCTHLFQLPGALFVVVAITIAGASLSMRIPRWVEVTS MMAR_4656|M.marinum_M TMAGGAVAAGVEFACTRLFELPGALFVVVAVTVAGALLSMRIPRWVEVTA MUL_0274|M.ulcerans_Agy99 TMAGGAVAAGVEFACTRLFELPGALFVVVAVTVAGALLSMRIPRWVEVTA MLBr_02143|M.leprae_Br4923 TIAGGAIAAGVEFVCAHLFKLPGALFVVAAITISGALLSMRIPRWVEVTA MAV_1005|M.avium_104 TIVGGAIAGGVEFVCTHLFKLPGALFVVVAVTVAGASLSMRIPRWVEVTA MAB_0875c|M.abscessus_ATCC_199 TIVGGAIAAGCELAFTRLLHLPGALFVVIAVTAVGAWASMRIPKWVEVTA *: **.:*.. * *..:****:*: *:: ** :****:***** Mflv_1711|M.gilvum_PYR-GCK GEVPATLSYHGATEMLPREP-AAATGR-------ARQPLGRNIITSLWGN Mvan_5040|M.vanbaalenii_PYR-1 GEVPTTLSYHGQTEGLRREPHGAVSAK-------TRQPLGRNIITALWGN MSMEG_5693|M.smegmatis_MC2_155 GEVPTTLSYHGGPGELRRPEHPDTTGKPDKP-QSVRQPMGRNTITALWGN TH_1066|M.thermoresistible__bu GEVPATLTYHG---DLRRHPDQRRHSG------AARQPMGRNTITALWGN Mb0900c|M.bovis_AF2122/97 GEVPATLSYHRDRGRLRRRWPEEVKNLG----GTLRQPLGRNIITSLWGN Rv0876c|M.tuberculosis_H37Rv GEVPATLSYHRDRGRLRRRWPEEVKNLG----GTLRQPLGRNIITSLWGN MMAR_4656|M.marinum_M GEVPATLSYHRDRGRQRRSWPEEVKNLS----GALRQPLGRNIITSLWGN MUL_0274|M.ulcerans_Agy99 GEVPATLSYHRDRGRQRRSWPEEVKNLS----GALRQPLGRNIITSLWGN MLBr_02143|M.leprae_Br4923 GEIPATLSYRLHRKPLRQSWPEEVKKVS----GRLRQPLGRNIITSLWGN MAV_1005|M.avium_104 GEVPATLSYRRDSEPLRRRWPEEVKNVPKKATATLRQPLGRNIITSLWGN MAB_0875c|M.abscessus_ATCC_199 GEVPTTFGYHGDDGEHPTILLRRSHKQP----EKVRQPLGRNIITSLWGN **:*:*: *: ***:*** **:**** Mflv_1711|M.gilvum_PYR-GCK CTVKVMVGFLFLYPAFVAKAHDASGWEQLRILGMIGAAAAIGNFGGNFTA Mvan_5040|M.vanbaalenii_PYR-1 CTVKVMVGFLFLYPAFVAKAHDASGWEQLRILGMIGAAAAVGNFAGNFTA MSMEG_5693|M.smegmatis_MC2_155 CTIKVMVGFLFLYPAFVAKSHDASGWEQLLILGIIGAAAGIGNFAGNMTA TH_1066|M.thermoresistible__bu CTIKLMVGFLFLYPAFVAKSHEATGLEQLMILGLIGAAAAVGNFIGNFTA Mb0900c|M.bovis_AF2122/97 CTIKVMVGFLFLYPAFVAKAHEANGWVQLGMLGLIGAAAAVGNFAGNFTS Rv0876c|M.tuberculosis_H37Rv CTIKVMVGFLFLYPAFVAKAHEANGWVQLGMLGLIGAAAAVGNFAGNFTS MMAR_4656|M.marinum_M CTIKVMVGFLFLYPAFVAKAHDANGWVQLGMLGLIGAAAAIGNFAGNFAS MUL_0274|M.ulcerans_Agy99 CTIKVMVGFLFLYPAFVAKAHDANGWVQLGMLGLIGAAAAIGNFAGNFAS MLBr_02143|M.leprae_Br4923 CTIKVMVGFLFLYPAFVAKEHQANGWVQLGMLGLIGTAAAIGNFAGNFTS MAV_1005|M.avium_104 CTIKVMVGFLFLYPAFVAKAHQANGWAQLAMLGMIGAAAGVGNFVGNFTS MAB_0875c|M.abscessus_ATCC_199 STIKVMVGFLTLYPAFVAKSHDAHGFQQLAMLGMVGAAAGIGNFAGNATS .*:*:***** ******** *:* * ** :**::*:**.:*** ** :: Mflv_1711|M.gilvum_PYR-GCK ARLKLGHPARLVVRCAIAVTVVALATALTGNLFVAAAATLVTSAASAIAK Mvan_5040|M.vanbaalenii_PYR-1 ARLKLGHPARLVVRCATAVTVMALATALSGNLLVAAAATLVTSGASAIAK MSMEG_5693|M.smegmatis_MC2_155 ARLKLGHPAQMVVRLAIVVTVFALLAALTGKLLVAALATLVTSGASAIAK TH_1066|M.thermoresistible__bu ARLELGHPAQLVVRAAIAVTIGALATAVTGELLVAALATLITSGASAIAK Mb0900c|M.bovis_AF2122/97 ARLQLGRPAVLVVRCTVLVTVLAIAAAVAGSLAATAIATLITAGSSAIAK Rv0876c|M.tuberculosis_H37Rv ARLQLGRPAVLVVRCTVLVTVLAIAAAVAGSLAATAIATLITAGSSAIAK MMAR_4656|M.marinum_M ARLQLGRPAVLVVRCTVVVTAFALAAAVAGNLVTAAIATLVTSGSSAIAK MUL_0274|M.ulcerans_Agy99 ARLQLGRPAVLVVRCTMVVTAFALAAAVAGNLVTAAIATLVTSASSAIAK MLBr_02143|M.leprae_Br4923 ARLQLGRPAVLVVRCTIAVTVLALAASVAGNLLMTTIATLITSGSSAIAK MAV_1005|M.avium_104 ARLKLGRPAVLVVRCTVAVTAVALAASVAGNLMLAVIATLVTSGASAIAK MAB_0875c|M.abscessus_ATCC_199 ARLKLGRPALLVVRCASAVTVVALAAAVTGVLAVVVVATLVTSAVSAIAK ***:**:** :*** : ** *: ::::* * .. ***:*:. ***** Mflv_1711|M.gilvum_PYR-GCK ASLDASIQDDLPEESRASGFGRSESLLQLAWVAGGATGVLIYTELYAGFT Mvan_5040|M.vanbaalenii_PYR-1 ASLDASLQDDLPEESRASAFGRSESLLQLAWVAGGATGVLIYTELYAGFT MSMEG_5693|M.smegmatis_MC2_155 ASLDASLQDDLPEASRASAFGRSESVLQLAWVAGGAIGVLIYTDLSVGFT TH_1066|M.thermoresistible__bu ASLDASLQDDLPEQSRASAFGRSESLLQLAWVAGGATGVLVYTELWIGFT Mb0900c|M.bovis_AF2122/97 ASLDASLQHDLPEESRASGFGRSESTLQLAWVLGGAVGVLVYTELWVGFT Rv0876c|M.tuberculosis_H37Rv ASLDASLQHDLPEESRASGFGRSESTLQLAWVLGGAVGVLVYTELWVGFT MMAR_4656|M.marinum_M ASLDASLQHDLPEESRASGFGRSESTLQLAWVLGGAVGVLIYTDLWIGFT MUL_0274|M.ulcerans_Agy99 ASLDASLQHDLPEESRASGFGRSESTLQLAWVLGGAVGVLIYTDLWIGFT MLBr_02143|M.leprae_Br4923 ASLDASLQNDLPEESRASGFGRSESTLQLAWVLGGALGVMVYTDLWVGFT MAV_1005|M.avium_104 ASLDAALQDDLPEESRASGFGRSESTLQLAWVLGGALGVLVYTELWVGFT MAB_0875c|M.abscessus_ATCC_199 ASLDASLQDDLPEESRASAFGRSEALLQLSWVLGGAIGVMIYTDLWVGFT *****::*.**** ****.*****: ***:** *** **::**:* *** Mflv_1711|M.gilvum_PYR-GCK AITAILILGLAQTVLSYRGESLVPGLGGNRPVHAEQEGVRTD---AVVTR Mvan_5040|M.vanbaalenii_PYR-1 TITAILILGLAQTVLSYRGESLVPGFGGNRPVLAEQEGVWTD---AAVTR MSMEG_5693|M.smegmatis_MC2_155 TITAVLILGLAQTIVSYRGESLIPGFGGNRPVLAEREGTMAW---GAR-- TH_1066|M.thermoresistible__bu TISAILILGLAQTIVSYRGDSLIPGFGGNRPVLAEPEGRNDH---PAFTP Mb0900c|M.bovis_AF2122/97 AVSALLILGLAQTIVSFRGDSLIPGLGGNRPVMAEQETTRRG---AAVAP Rv0876c|M.tuberculosis_H37Rv AVSALLILGLAQTIVSFRGDSLIPGLGGNRPVMAEQETTRRG---AAVAP MMAR_4656|M.marinum_M TVSALLILGLAQTIVSFRGDSLIPGLGGNRPVMAEQETTRRGSATAGVGP MUL_0274|M.ulcerans_Agy99 TVSALLILGLAQTIVSFRGDSLIPGLGGNRPVMAEQETTRRGTATAGVGP MLBr_02143|M.leprae_Br4923 AVSALLILGLAQTVVSFRGDSLIPGLGGNRPVMIEQESMRRA---AAVSP MAV_1005|M.avium_104 AVTALLILGLAQTLVSFRGNSLIPGLGGNRPIMVEQEGARRGVGRPAVVA MAB_0875c|M.abscessus_ATCC_199 VISAVLILGLAQTLASFRGVSLIPGLGGNRPVMAEQEGGKVHA------- .::*:********: *:** **:**:*****: * * Mflv_1711|M.gilvum_PYR-GCK E Mvan_5040|M.vanbaalenii_PYR-1 E MSMEG_5693|M.smegmatis_MC2_155 - TH_1066|M.thermoresistible__bu R Mb0900c|M.bovis_AF2122/97 Q Rv0876c|M.tuberculosis_H37Rv Q MMAR_4656|M.marinum_M Q MUL_0274|M.ulcerans_Agy99 Q MLBr_02143|M.leprae_Br4923 Q MAV_1005|M.avium_104 E MAB_0875c|M.abscessus_ATCC_199 -