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APTPGRRTRNGSVNGHPGMANYPPDDANYRRSRRPPPMPSANRYLPPLGEQPEPERSRVPPRTTRAGERI TVTRAAAMRSREMGSRMYLLVHRAATADGADKSGLTALTWPVMANFAVDSAMAVALANTLFFAAASGESK SRVALYLLITIAPFAVIAPLIGPALDRLQHGRRVALALSFGLRTALAVVLIMNYDGATGSFPSWVLYPCA LAMMVFSKSFSVLRSAVTPRVMPPTIDLVRVNSRLTVFGLLGGTIAGGAIAAGVEFVCTHLFQLPGALFV VVAITIAGASLSMRIPRWVEVTSGEVPATLSYHRDRGRLRRRWPEEVKNLGGTLRQPLGRNIITSLWGNC TIKVMVGFLFLYPAFVAKAHEANGWVQLGMLGLIGAAAAVGNFAGNFTSARLQLGRPAVLVVRCTVLVTV LAIAAAVAGSLAATAIATLITAGSSAIAKASLDASLQHDLPEESRASGFGRSESTLQLAWVLGGAVGVLV YTELWVGFTAVSALLILGLAQTIVSFRGDSLIPGLGGNRPVMAEQETTRRGAAVAPQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0876c | - | - | 100% (548) | POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0900c | - | 0.0 | 99.82% (548) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_1711 | - | 0.0 | 72.34% (535) | major facilitator transporter |
| M. leprae Br4923 | MLBr_02143 | - | 0.0 | 80.99% (568) | hypothetical protein MLBr_02143 |
| M. abscessus ATCC 19977 | MAB_0875c | - | 0.0 | 72.01% (543) | hypothetical protein MAB_0875c |
| M. marinum M | MMAR_4656 | - | 0.0 | 86.44% (553) | transmembrane protein |
| M. avium 104 | MAV_1005 | - | 0.0 | 83.36% (547) | hypothetical protein MAV_1005 |
| M. smegmatis MC2 155 | MSMEG_5693 | - | 0.0 | 75.00% (512) | transporter, major facilitator family protein |
| M. thermoresistible (build 8) | TH_1066 | - | 0.0 | 75.46% (538) | POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_0274 | - | 0.0 | 86.08% (553) | transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_5040 | - | 0.0 | 75.09% (534) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1711|M.gilvum_PYR-GCK ----------------------------------MANYPSDPQTRPGNRR
Mvan_5040|M.vanbaalenii_PYR-1 ---MTGSRRDHRDPDGQQGGRYYPPRPPAGEHPGMANYPSDPAMSPGNRR
MSMEG_5693|M.smegmatis_MC2_155 --------------------------------------------------
TH_1066|M.thermoresistible__bu ----------------------------------MANYPSD---DPAPRR
Rv0876c|M.tuberculosis_H37Rv --------------MAPTPGRR-TRNGSVNGHPGMANYPPD---DANYRR
Mb0900c|M.bovis_AF2122/97 --------------MAPTPGRR-TRNGSVNGHPGMANYPPG---DANYRR
MMAR_4656|M.marinum_M ---MSGWRRDHQGRMAASPGRR-TRNGSVSEHPGMANYPTD---GPGNRR
MUL_0274|M.ulcerans_Agy99 ---MSGWRRDHQGRMAASPGRR-TRNGSVSEHPGMANYPTD---GPGNRR
MLBr_02143|M.leprae_Br4923 ---MSGRRRNHPGRLASIPGLR-TRTGSRNQHPGIANYPAD---SSDFRP
MAV_1005|M.avium_104 ---MSGRRQGDPGRVAAKPGRR-PGNSAAAPHPGAANYPAG---DTGDRR
MAB_0875c|M.abscessus_ATCC_199 MRDDYARFGNRHGSSDSPSRRRNQDPRDANSHPGMANYPTG----SAPRE
Mflv_1711|M.gilvum_PYR-GCK P------------------GRPYSPGQAGNRWLPPLDDDPRRAGR---DY
Mvan_5040|M.vanbaalenii_PYR-1 S------------------GRPGPSSQSANRWLPPLDDSSRPHGH---SY
MSMEG_5693|M.smegmatis_MC2_155 -------------------------MPSSNRWLPPLDEESPRAER---TG
TH_1066|M.thermoresistible__bu P------------------GRPKAP-PSANRWLPPLDEDRPTFDRGAGEP
Rv0876c|M.tuberculosis_H37Rv S-------------------RRPPPMPSANRYLPPLGEQ-PEPE-----R
Mb0900c|M.bovis_AF2122/97 S-------------------RRPPPMPSANRYLPPLGEQ-PEPE-----R
MMAR_4656|M.marinum_M T-------------------RRPPPMPSANRYLPPLDRE-PESEDDA-EG
MUL_0274|M.ulcerans_Agy99 T-------------------RRPPPMPSANRYLPPLDRE-PESEDDA-EG
MLBr_02143|M.leprae_Br4923 AQQRRALEQREQQAGQLDPARRSPSMPSANRYLPPLGQQQSEPQ-----H
MAV_1005|M.avium_104 T-------------------RRPPPMPSANRYLPPLGHQ-PQPD----RG
MAB_0875c|M.abscessus_ATCC_199 R---------------------LRASSSSNRYLPPLGEERRERVR-----
:.**:****. .
Mflv_1711|M.gilvum_PYR-GCK DSRYHDAPSAA-GGEKVTVTRAAAQRSREMGSKVYGMVHRAATADGADKS
Mvan_5040|M.vanbaalenii_PYR-1 PP----PPGRG-ADEKVTVTRAAAQRSREMGSKMYGLVHRAATADGADKS
MSMEG_5693|M.smegmatis_MC2_155 SARGAGPTAEPGAGERVTVTRAAAARSREMGSRMYGLVHRAATADGADKS
TH_1066|M.thermoresistible__bu PPRGYRSTGRPRSDERITVTRAAAQRSREMGSRMYGLVHRAATADGADKS
Rv0876c|M.tuberculosis_H37Rv SRVPPRTTR---AGERITVTRAAAMRSREMGSRMYLLVHRAATADGADKS
Mb0900c|M.bovis_AF2122/97 SRVPPRTTR---AGERITVTRAAAMRSREMGSRMYLLVHRAATADGADKS
MMAR_4656|M.marinum_M NEAPPPSPRGLSSGERITVTRAAAMRSREMGSRMYWMVQRAATADGADKS
MUL_0274|M.ulcerans_Agy99 NEAPPPPPRGLSSGERITVTRAAAMRSREMGSRMYWMVQRAATADGADKS
MLBr_02143|M.leprae_Br4923 NSAPPCGPY---PGERIKVTRAAAQRSREMGYRMYWMVQRAATADGADKS
MAV_1005|M.avium_104 AGAPPRGPV---AGERITVTRAAALRSREMGSRMYWMVQRAATADGADKS
MAB_0875c|M.abscessus_ATCC_199 ----RRPPPEQDHPQKLTVTRVAAMRSREMGSRMYGLFQKAATADGADKS
. :::.***.** ****** ::* :.::**********
Mflv_1711|M.gilvum_PYR-GCK GLTALTWPVVANFAVDAAMAVALANTLFFAAASGESKGKVALYLLITIAP
Mvan_5040|M.vanbaalenii_PYR-1 GLTALTWPVVANFAVDAAMAVALANTLFFAAASGESKSRVALYLLITIAP
MSMEG_5693|M.smegmatis_MC2_155 GLTALTWPVVANFAVDAAMAVALANTLFFAAASGESKSRVALYLLITIAP
TH_1066|M.thermoresistible__bu GLTALTWPVVANFAVDAAMAVALANTLFFAAATGESKARVALYLLITIAP
Rv0876c|M.tuberculosis_H37Rv GLTALTWPVMANFAVDSAMAVALANTLFFAAASGESKSRVALYLLITIAP
Mb0900c|M.bovis_AF2122/97 GLTALTWPVMANFAVDSAMAVALANTLFFAAASGESKSRVALYLLITIAP
MMAR_4656|M.marinum_M GLTALTWPTMANFAVDSSMAVALANTLFFAAASGESKSKVALYLLITIAP
MUL_0274|M.ulcerans_Agy99 GLTALTWPTMANFAVDSSMAVALANTLFFAAASGESKSKVALYLLITIAP
MLBr_02143|M.leprae_Br4923 GLTALTWPVVTNFAVDSAMAVALANTLFFAAASGESKSKVALYLLITIAP
MAV_1005|M.avium_104 GLTALTWPVVANFAVDAAMAVALANTLFFAAATGESKGRVALYLLITIAP
MAB_0875c|M.abscessus_ATCC_199 GLTALTYPVMANFAVDAAMAVALANTLFFAAATAESKSKVALYLLITIAP
******:*.::*****::**************:.***.:***********
Mflv_1711|M.gilvum_PYR-GCK FAVIAPLIGPALDRLQHGRRVALAASFVLRTVLAVVLIANFDSATGSFPS
Mvan_5040|M.vanbaalenii_PYR-1 FAVIAPLIGPALDRLQHGRRVALAASFSLRTVLAVVLIANFDSATGSFPS
MSMEG_5693|M.smegmatis_MC2_155 FAVIAPLIGPALDRLQHGRRVALAASFALRTVLIVVLIANYDGATGNFPS
TH_1066|M.thermoresistible__bu FAVIAPLIGPALDRLQHGRRVALATSFGLRTALVVVLIANYDGATGSFPS
Rv0876c|M.tuberculosis_H37Rv FAVIAPLIGPALDRLQHGRRVALALSFGLRTALAVVLIMNYDGATGSFPS
Mb0900c|M.bovis_AF2122/97 FAVIAPLIGPALDRLQHGRRVALALSFGLRTALAVVLIMNYDGATGSFPS
MMAR_4656|M.marinum_M FAVVAPLIGPALDKLQHGRRVALALSFGLRTVLALVLIMNYDGASGSFPS
MUL_0274|M.ulcerans_Agy99 FAVVAPLIGPALDKLQHGRRVALALSFGLRTVLALVLIMNYDGASGSFPS
MLBr_02143|M.leprae_Br4923 FAVIAPLIGPALDRLQHGRRVALATSFVLRTGLATLLIMNYDGATGSYPS
MAV_1005|M.avium_104 FAVIAPLIGPALDRLQHGRRVALAASFVLRTALAAVLIMNYDGASGSYPS
MAB_0875c|M.abscessus_ATCC_199 FAVIAPLIGPALDRLQHGRRAALAASFGLRTLLAVIMIANYDGASGSFPP
***:*********:******.*** ** *** * ::* *:*.*:*.:*.
Mflv_1711|M.gilvum_PYR-GCK WVLYPCALGMMVLSKSFSVLRSAVTPRVLPPSIDLVRVNSRLTTFGLLGG
Mvan_5040|M.vanbaalenii_PYR-1 WVLYPCALGMMVLSKSFSVLRSAVTPRVLPPTIDLVRVNSRLTTFGLLGG
MSMEG_5693|M.smegmatis_MC2_155 WVLYPCALGMMVLSKSFSVLRSAVTPRVLPPTIDLVRVNSRLTTFGLLGG
TH_1066|M.thermoresistible__bu WVLYPCALAMMVLSKSFSVLRSAMTPRVLPPTIDLVRVNSRLTMFGLLGG
Rv0876c|M.tuberculosis_H37Rv WVLYPCALAMMVFSKSFSVLRSAVTPRVMPPTIDLVRVNSRLTVFGLLGG
Mb0900c|M.bovis_AF2122/97 WVLYPCALAMMVFSKSFSVLRSAVTPRVMPPTIDLVRVNSRLTVFGLLGG
MMAR_4656|M.marinum_M WVLYPCALAMMVLSKSFSVLRSAMTPRVMPPSIDLVRVNSRLTVFGLLGG
MUL_0274|M.ulcerans_Agy99 WVLYPCALAMMVLSKSFSVLRSAMTPRVMPPSIDLVRVNSRLTVFGLLGG
MLBr_02143|M.leprae_Br4923 MVLYPCALAMMVLSKSFSVLRSAVTPRVMPPSIDLVRVNSRLTVFGLLGG
MAV_1005|M.avium_104 MVLYPCALAMMVLSKSFSVLRSAVTPRVMPPSIDLVRVNSRLTMFGLLGG
MAB_0875c|M.abscessus_ATCC_199 WVLYPCALSMLVLSKSFGVLRGAVTPRVLPPTIDLVRVNSRLTTFGLVGG
*******.*:*:****.***.*:****:**:*********** ***:**
Mflv_1711|M.gilvum_PYR-GCK TMIGGGIAAAAEYGFQ-LFQMPGALYVVVAVTVAGAVLAMRIPKWVEVTE
Mvan_5040|M.vanbaalenii_PYR-1 TMIGGGIAAAAEWGFQ-LFQMPGALYVVVAVTIGGAVLAMRIPKWVEVTA
MSMEG_5693|M.smegmatis_MC2_155 TVAGGGVAAGAEYLFG-LVHLPGALYVIVAVSVAGAVLSMRIPKWVEVTE
TH_1066|M.thermoresistible__bu TMLGGAVAAAAEYVFN-LFELPGALYVIVAVSLAGAVLSMRIPRWVEVTE
Rv0876c|M.tuberculosis_H37Rv TIAGGAIAAGVEFVCTHLFQLPGALFVVVAITIAGASLSMRIPRWVEVTS
Mb0900c|M.bovis_AF2122/97 TIAGGAIAAGVEFVCTHLFQLPGALFVVVAITIAGASLSMRIPRWVEVTS
MMAR_4656|M.marinum_M TMAGGAVAAGVEFACTRLFELPGALFVVVAVTVAGALLSMRIPRWVEVTA
MUL_0274|M.ulcerans_Agy99 TMAGGAVAAGVEFACTRLFELPGALFVVVAVTVAGALLSMRIPRWVEVTA
MLBr_02143|M.leprae_Br4923 TIAGGAIAAGVEFVCAHLFKLPGALFVVAAITISGALLSMRIPRWVEVTA
MAV_1005|M.avium_104 TIVGGAIAGGVEFVCTHLFKLPGALFVVVAVTVAGASLSMRIPRWVEVTA
MAB_0875c|M.abscessus_ATCC_199 TIVGGAIAAGCELAFTRLLHLPGALFVVIAVTAVGAWASMRIPKWVEVTA
*: **.:*.. * *..:****:*: *:: ** :****:*****
Mflv_1711|M.gilvum_PYR-GCK GEVPATLSYHGATEMLPREP-AAATGR-------ARQPLGRNIITSLWGN
Mvan_5040|M.vanbaalenii_PYR-1 GEVPTTLSYHGQTEGLRREPHGAVSAK-------TRQPLGRNIITALWGN
MSMEG_5693|M.smegmatis_MC2_155 GEVPTTLSYHGGPGELRRPEHPDTTGKPDKP-QSVRQPMGRNTITALWGN
TH_1066|M.thermoresistible__bu GEVPATLTYHG---DLRRHPDQRRHSG------AARQPMGRNTITALWGN
Rv0876c|M.tuberculosis_H37Rv GEVPATLSYHRDRGRLRRRWPEEVKNLG----GTLRQPLGRNIITSLWGN
Mb0900c|M.bovis_AF2122/97 GEVPATLSYHRDRGRLRRRWPEEVKNLG----GTLRQPLGRNIITSLWGN
MMAR_4656|M.marinum_M GEVPATLSYHRDRGRQRRSWPEEVKNLS----GALRQPLGRNIITSLWGN
MUL_0274|M.ulcerans_Agy99 GEVPATLSYHRDRGRQRRSWPEEVKNLS----GALRQPLGRNIITSLWGN
MLBr_02143|M.leprae_Br4923 GEIPATLSYRLHRKPLRQSWPEEVKKVS----GRLRQPLGRNIITSLWGN
MAV_1005|M.avium_104 GEVPATLSYRRDSEPLRRRWPEEVKNVPKKATATLRQPLGRNIITSLWGN
MAB_0875c|M.abscessus_ATCC_199 GEVPTTFGYHGDDGEHPTILLRRSHKQP----EKVRQPLGRNIITSLWGN
**:*:*: *: ***:*** **:****
Mflv_1711|M.gilvum_PYR-GCK CTVKVMVGFLFLYPAFVAKAHDASGWEQLRILGMIGAAAAIGNFGGNFTA
Mvan_5040|M.vanbaalenii_PYR-1 CTVKVMVGFLFLYPAFVAKAHDASGWEQLRILGMIGAAAAVGNFAGNFTA
MSMEG_5693|M.smegmatis_MC2_155 CTIKVMVGFLFLYPAFVAKSHDASGWEQLLILGIIGAAAGIGNFAGNMTA
TH_1066|M.thermoresistible__bu CTIKLMVGFLFLYPAFVAKSHEATGLEQLMILGLIGAAAAVGNFIGNFTA
Rv0876c|M.tuberculosis_H37Rv CTIKVMVGFLFLYPAFVAKAHEANGWVQLGMLGLIGAAAAVGNFAGNFTS
Mb0900c|M.bovis_AF2122/97 CTIKVMVGFLFLYPAFVAKAHEANGWVQLGMLGLIGAAAAVGNFAGNFTS
MMAR_4656|M.marinum_M CTIKVMVGFLFLYPAFVAKAHDANGWVQLGMLGLIGAAAAIGNFAGNFAS
MUL_0274|M.ulcerans_Agy99 CTIKVMVGFLFLYPAFVAKAHDANGWVQLGMLGLIGAAAAIGNFAGNFAS
MLBr_02143|M.leprae_Br4923 CTIKVMVGFLFLYPAFVAKEHQANGWVQLGMLGLIGTAAAIGNFAGNFTS
MAV_1005|M.avium_104 CTIKVMVGFLFLYPAFVAKAHQANGWAQLAMLGMIGAAAGVGNFVGNFTS
MAB_0875c|M.abscessus_ATCC_199 STIKVMVGFLTLYPAFVAKSHDAHGFQQLAMLGMVGAAAGIGNFAGNATS
.*:*:***** ******** *:* * ** :**::*:**.:*** ** ::
Mflv_1711|M.gilvum_PYR-GCK ARLKLGHPARLVVRCAIAVTVVALATALTGNLFVAAAATLVTSAASAIAK
Mvan_5040|M.vanbaalenii_PYR-1 ARLKLGHPARLVVRCATAVTVMALATALSGNLLVAAAATLVTSGASAIAK
MSMEG_5693|M.smegmatis_MC2_155 ARLKLGHPAQMVVRLAIVVTVFALLAALTGKLLVAALATLVTSGASAIAK
TH_1066|M.thermoresistible__bu ARLELGHPAQLVVRAAIAVTIGALATAVTGELLVAALATLITSGASAIAK
Rv0876c|M.tuberculosis_H37Rv ARLQLGRPAVLVVRCTVLVTVLAIAAAVAGSLAATAIATLITAGSSAIAK
Mb0900c|M.bovis_AF2122/97 ARLQLGRPAVLVVRCTVLVTVLAIAAAVAGSLAATAIATLITAGSSAIAK
MMAR_4656|M.marinum_M ARLQLGRPAVLVVRCTVVVTAFALAAAVAGNLVTAAIATLVTSGSSAIAK
MUL_0274|M.ulcerans_Agy99 ARLQLGRPAVLVVRCTMVVTAFALAAAVAGNLVTAAIATLVTSASSAIAK
MLBr_02143|M.leprae_Br4923 ARLQLGRPAVLVVRCTIAVTVLALAASVAGNLLMTTIATLITSGSSAIAK
MAV_1005|M.avium_104 ARLKLGRPAVLVVRCTVAVTAVALAASVAGNLMLAVIATLVTSGASAIAK
MAB_0875c|M.abscessus_ATCC_199 ARLKLGRPALLVVRCASAVTVVALAAAVTGVLAVVVVATLVTSAVSAIAK
***:**:** :*** : ** *: ::::* * .. ***:*:. *****
Mflv_1711|M.gilvum_PYR-GCK ASLDASIQDDLPEESRASGFGRSESLLQLAWVAGGATGVLIYTELYAGFT
Mvan_5040|M.vanbaalenii_PYR-1 ASLDASLQDDLPEESRASAFGRSESLLQLAWVAGGATGVLIYTELYAGFT
MSMEG_5693|M.smegmatis_MC2_155 ASLDASLQDDLPEASRASAFGRSESVLQLAWVAGGAIGVLIYTDLSVGFT
TH_1066|M.thermoresistible__bu ASLDASLQDDLPEQSRASAFGRSESLLQLAWVAGGATGVLVYTELWIGFT
Rv0876c|M.tuberculosis_H37Rv ASLDASLQHDLPEESRASGFGRSESTLQLAWVLGGAVGVLVYTELWVGFT
Mb0900c|M.bovis_AF2122/97 ASLDASLQHDLPEESRASGFGRSESTLQLAWVLGGAVGVLVYTELWVGFT
MMAR_4656|M.marinum_M ASLDASLQHDLPEESRASGFGRSESTLQLAWVLGGAVGVLIYTDLWIGFT
MUL_0274|M.ulcerans_Agy99 ASLDASLQHDLPEESRASGFGRSESTLQLAWVLGGAVGVLIYTDLWIGFT
MLBr_02143|M.leprae_Br4923 ASLDASLQNDLPEESRASGFGRSESTLQLAWVLGGALGVMVYTDLWVGFT
MAV_1005|M.avium_104 ASLDAALQDDLPEESRASGFGRSESTLQLAWVLGGALGVLVYTELWVGFT
MAB_0875c|M.abscessus_ATCC_199 ASLDASLQDDLPEESRASAFGRSEALLQLSWVLGGAIGVMIYTDLWVGFT
*****::*.**** ****.*****: ***:** *** **::**:* ***
Mflv_1711|M.gilvum_PYR-GCK AITAILILGLAQTVLSYRGESLVPGLGGNRPVHAEQEGVRTD---AVVTR
Mvan_5040|M.vanbaalenii_PYR-1 TITAILILGLAQTVLSYRGESLVPGFGGNRPVLAEQEGVWTD---AAVTR
MSMEG_5693|M.smegmatis_MC2_155 TITAVLILGLAQTIVSYRGESLIPGFGGNRPVLAEREGTMAW---GAR--
TH_1066|M.thermoresistible__bu TISAILILGLAQTIVSYRGDSLIPGFGGNRPVLAEPEGRNDH---PAFTP
Rv0876c|M.tuberculosis_H37Rv AVSALLILGLAQTIVSFRGDSLIPGLGGNRPVMAEQETTRRG---AAVAP
Mb0900c|M.bovis_AF2122/97 AVSALLILGLAQTIVSFRGDSLIPGLGGNRPVMAEQETTRRG---AAVAP
MMAR_4656|M.marinum_M TVSALLILGLAQTIVSFRGDSLIPGLGGNRPVMAEQETTRRGSATAGVGP
MUL_0274|M.ulcerans_Agy99 TVSALLILGLAQTIVSFRGDSLIPGLGGNRPVMAEQETTRRGTATAGVGP
MLBr_02143|M.leprae_Br4923 AVSALLILGLAQTVVSFRGDSLIPGLGGNRPVMIEQESMRRA---AAVSP
MAV_1005|M.avium_104 AVTALLILGLAQTLVSFRGNSLIPGLGGNRPIMVEQEGARRGVGRPAVVA
MAB_0875c|M.abscessus_ATCC_199 VISAVLILGLAQTLASFRGVSLIPGLGGNRPVMAEQEGGKVHA-------
.::*:********: *:** **:**:*****: * *
Mflv_1711|M.gilvum_PYR-GCK E
Mvan_5040|M.vanbaalenii_PYR-1 E
MSMEG_5693|M.smegmatis_MC2_155 -
TH_1066|M.thermoresistible__bu R
Rv0876c|M.tuberculosis_H37Rv Q
Mb0900c|M.bovis_AF2122/97 Q
MMAR_4656|M.marinum_M Q
MUL_0274|M.ulcerans_Agy99 Q
MLBr_02143|M.leprae_Br4923 Q
MAV_1005|M.avium_104 E
MAB_0875c|M.abscessus_ATCC_199 -