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M. marinum M MMAR_4656 (-)

annotation: transmembrane protein
coordinates: 5708785 - 5710494
length: 569

VSGWRRDHQGRMAASPGRRTRNGSVSEHPGMANYPTDGPGNRRTRRPPPMPSANRYLPPLDREPESEDDA
EGNEAPPPSPRGLSSGERITVTRAAAMRSREMGSRMYWMVQRAATADGADKSGLTALTWPTMANFAVDSS
MAVALANTLFFAAASGESKSKVALYLLITIAPFAVVAPLIGPALDKLQHGRRVALALSFGLRTVLALVLI
MNYDGASGSFPSWVLYPCALAMMVLSKSFSVLRSAMTPRVMPPSIDLVRVNSRLTVFGLLGGTMAGGAVA
AGVEFACTRLFELPGALFVVVAVTVAGALLSMRIPRWVEVTAGEVPATLSYHRDRGRQRRSWPEEVKNLS
GALRQPLGRNIITSLWGNCTIKVMVGFLFLYPAFVAKAHDANGWVQLGMLGLIGAAAAIGNFAGNFASAR
LQLGRPAVLVVRCTVVVTAFALAAAVAGNLVTAAIATLVTSGSSAIAKASLDASLQHDLPEESRASGFGR
SESTLQLAWVLGGAVGVLIYTDLWIGFTTVSALLILGLAQTIVSFRGDSLIPGLGGNRPVMAEQETTRRG
SATAGVGPQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_4656--100% (569)transmembrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0900c-0.086.26% (553) transmembrane protein
M. gilvum PYR-GCKMflv_1711-0.073.92% (533) major facilitator transporter
M. tuberculosis H37RvRv0876c-0.086.44% (553) transmembrane protein
M. leprae Br4923MLBr_02143-0.078.23% (588) hypothetical protein MLBr_02143
M. abscessus ATCC 19977MAB_0875c-0.070.99% (548) hypothetical protein MAB_0875c
M. avium 104MAV_1005-0.080.85% (564) hypothetical protein MAV_1005
M. smegmatis MC2 155MSMEG_5693-0.074.90% (514) transporter, major facilitator family protein
M. thermoresistible (build 8)TH_1066-0.075.57% (528) POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN
M. ulcerans Agy99MUL_0274-0.099.30% (569) transmembrane protein
M. vanbaalenii PYR-1Mvan_5040-0.072.32% (560) major facilitator superfamily transporter

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1711|M.gilvum_PYR-GCK          ----------------------------------MANYPSDPQTRPGNRR
Mvan_5040|M.vanbaalenii_PYR-1       ---MTGSRRDHRDPDGQQGGRYYPPRPPAGEHPGMANYPSDPAMSPGNRR
MSMEG_5693|M.smegmatis_MC2_155      --------------------------------------------------
TH_1066|M.thermoresistible__bu      ----------------------------------MANYPSD---DPAPRR
MMAR_4656|M.marinum_M               ---MSGWRRDHQGRMAASPGRR-TRNGSVSEHPGMANYPTD---GPGNRR
MUL_0274|M.ulcerans_Agy99           ---MSGWRRDHQGRMAASPGRR-TRNGSVSEHPGMANYPTD---GPGNRR
Mb0900c|M.bovis_AF2122/97           --------------MAPTPGRR-TRNGSVNGHPGMANYPPG---DANYRR
Rv0876c|M.tuberculosis_H37Rv        --------------MAPTPGRR-TRNGSVNGHPGMANYPPD---DANYRR
MLBr_02143|M.leprae_Br4923          ---MSGRRRNHPGRLASIPGLR-TRTGSRNQHPGIANYPAD---SSDFRP
MAV_1005|M.avium_104                ---MSGRRQGDPGRVAAKPGRR-PGNSAAAPHPGAANYPAG---DTGDRR
MAB_0875c|M.abscessus_ATCC_199      MRDDYARFGNRHGSSDSPSRRRNQDPRDANSHPGMANYPTG----SAPRE
                                                                                      

Mflv_1711|M.gilvum_PYR-GCK          P------------------GRPYSPGQAGNRWLPPLDDDPRRAGR---DY
Mvan_5040|M.vanbaalenii_PYR-1       S------------------GRPGPSSQSANRWLPPLDDSSRPHGH---SY
MSMEG_5693|M.smegmatis_MC2_155      -------------------------MPSSNRWLPPLDEESPRAER---TG
TH_1066|M.thermoresistible__bu      P------------------GRPKAP-PSANRWLPPLDEDRPTFDRGAGEP
MMAR_4656|M.marinum_M               T-------------------RRPPPMPSANRYLPPLDRE-PESEDDA-EG
MUL_0274|M.ulcerans_Agy99           T-------------------RRPPPMPSANRYLPPLDRE-PESEDDA-EG
Mb0900c|M.bovis_AF2122/97           S-------------------RRPPPMPSANRYLPPLGEQ-PEPE-----R
Rv0876c|M.tuberculosis_H37Rv        S-------------------RRPPPMPSANRYLPPLGEQ-PEPE-----R
MLBr_02143|M.leprae_Br4923          AQQRRALEQREQQAGQLDPARRSPSMPSANRYLPPLGQQQSEPQ-----H
MAV_1005|M.avium_104                T-------------------RRPPPMPSANRYLPPLGHQ-PQPD----RG
MAB_0875c|M.abscessus_ATCC_199      R---------------------LRASSSSNRYLPPLGEERRERVR-----
                                                               :.**:****. .           

Mflv_1711|M.gilvum_PYR-GCK          DSRYHDAPSAA-GGEKVTVTRAAAQRSREMGSKVYGMVHRAATADGADKS
Mvan_5040|M.vanbaalenii_PYR-1       PP----PPGRG-ADEKVTVTRAAAQRSREMGSKMYGLVHRAATADGADKS
MSMEG_5693|M.smegmatis_MC2_155      SARGAGPTAEPGAGERVTVTRAAAARSREMGSRMYGLVHRAATADGADKS
TH_1066|M.thermoresistible__bu      PPRGYRSTGRPRSDERITVTRAAAQRSREMGSRMYGLVHRAATADGADKS
MMAR_4656|M.marinum_M               NEAPPPSPRGLSSGERITVTRAAAMRSREMGSRMYWMVQRAATADGADKS
MUL_0274|M.ulcerans_Agy99           NEAPPPPPRGLSSGERITVTRAAAMRSREMGSRMYWMVQRAATADGADKS
Mb0900c|M.bovis_AF2122/97           SRVPPRTTR---AGERITVTRAAAMRSREMGSRMYLLVHRAATADGADKS
Rv0876c|M.tuberculosis_H37Rv        SRVPPRTTR---AGERITVTRAAAMRSREMGSRMYLLVHRAATADGADKS
MLBr_02143|M.leprae_Br4923          NSAPPCGPY---PGERIKVTRAAAQRSREMGYRMYWMVQRAATADGADKS
MAV_1005|M.avium_104                AGAPPRGPV---AGERITVTRAAALRSREMGSRMYWMVQRAATADGADKS
MAB_0875c|M.abscessus_ATCC_199      ----RRPPPEQDHPQKLTVTRVAAMRSREMGSRMYGLFQKAATADGADKS
                                           .      :::.***.** ****** ::* :.::**********

Mflv_1711|M.gilvum_PYR-GCK          GLTALTWPVVANFAVDAAMAVALANTLFFAAASGESKGKVALYLLITIAP
Mvan_5040|M.vanbaalenii_PYR-1       GLTALTWPVVANFAVDAAMAVALANTLFFAAASGESKSRVALYLLITIAP
MSMEG_5693|M.smegmatis_MC2_155      GLTALTWPVVANFAVDAAMAVALANTLFFAAASGESKSRVALYLLITIAP
TH_1066|M.thermoresistible__bu      GLTALTWPVVANFAVDAAMAVALANTLFFAAATGESKARVALYLLITIAP
MMAR_4656|M.marinum_M               GLTALTWPTMANFAVDSSMAVALANTLFFAAASGESKSKVALYLLITIAP
MUL_0274|M.ulcerans_Agy99           GLTALTWPTMANFAVDSSMAVALANTLFFAAASGESKSKVALYLLITIAP
Mb0900c|M.bovis_AF2122/97           GLTALTWPVMANFAVDSAMAVALANTLFFAAASGESKSRVALYLLITIAP
Rv0876c|M.tuberculosis_H37Rv        GLTALTWPVMANFAVDSAMAVALANTLFFAAASGESKSRVALYLLITIAP
MLBr_02143|M.leprae_Br4923          GLTALTWPVVTNFAVDSAMAVALANTLFFAAASGESKSKVALYLLITIAP
MAV_1005|M.avium_104                GLTALTWPVVANFAVDAAMAVALANTLFFAAATGESKGRVALYLLITIAP
MAB_0875c|M.abscessus_ATCC_199      GLTALTYPVMANFAVDAAMAVALANTLFFAAATAESKSKVALYLLITIAP
                                    ******:*.::*****::**************:.***.:***********

Mflv_1711|M.gilvum_PYR-GCK          FAVIAPLIGPALDRLQHGRRVALAASFVLRTVLAVVLIANFDSATGSFPS
Mvan_5040|M.vanbaalenii_PYR-1       FAVIAPLIGPALDRLQHGRRVALAASFSLRTVLAVVLIANFDSATGSFPS
MSMEG_5693|M.smegmatis_MC2_155      FAVIAPLIGPALDRLQHGRRVALAASFALRTVLIVVLIANYDGATGNFPS
TH_1066|M.thermoresistible__bu      FAVIAPLIGPALDRLQHGRRVALATSFGLRTALVVVLIANYDGATGSFPS
MMAR_4656|M.marinum_M               FAVVAPLIGPALDKLQHGRRVALALSFGLRTVLALVLIMNYDGASGSFPS
MUL_0274|M.ulcerans_Agy99           FAVVAPLIGPALDKLQHGRRVALALSFGLRTVLALVLIMNYDGASGSFPS
Mb0900c|M.bovis_AF2122/97           FAVIAPLIGPALDRLQHGRRVALALSFGLRTALAVVLIMNYDGATGSFPS
Rv0876c|M.tuberculosis_H37Rv        FAVIAPLIGPALDRLQHGRRVALALSFGLRTALAVVLIMNYDGATGSFPS
MLBr_02143|M.leprae_Br4923          FAVIAPLIGPALDRLQHGRRVALATSFVLRTGLATLLIMNYDGATGSYPS
MAV_1005|M.avium_104                FAVIAPLIGPALDRLQHGRRVALAASFVLRTALAAVLIMNYDGASGSYPS
MAB_0875c|M.abscessus_ATCC_199      FAVIAPLIGPALDRLQHGRRAALAASFGLRTLLAVIMIANYDGASGSFPP
                                    ***:*********:******.*** ** *** *  ::* *:*.*:*.:*.

Mflv_1711|M.gilvum_PYR-GCK          WVLYPCALGMMVLSKSFSVLRSAVTPRVLPPSIDLVRVNSRLTTFGLLGG
Mvan_5040|M.vanbaalenii_PYR-1       WVLYPCALGMMVLSKSFSVLRSAVTPRVLPPTIDLVRVNSRLTTFGLLGG
MSMEG_5693|M.smegmatis_MC2_155      WVLYPCALGMMVLSKSFSVLRSAVTPRVLPPTIDLVRVNSRLTTFGLLGG
TH_1066|M.thermoresistible__bu      WVLYPCALAMMVLSKSFSVLRSAMTPRVLPPTIDLVRVNSRLTMFGLLGG
MMAR_4656|M.marinum_M               WVLYPCALAMMVLSKSFSVLRSAMTPRVMPPSIDLVRVNSRLTVFGLLGG
MUL_0274|M.ulcerans_Agy99           WVLYPCALAMMVLSKSFSVLRSAMTPRVMPPSIDLVRVNSRLTVFGLLGG
Mb0900c|M.bovis_AF2122/97           WVLYPCALAMMVFSKSFSVLRSAVTPRVMPPTIDLVRVNSRLTVFGLLGG
Rv0876c|M.tuberculosis_H37Rv        WVLYPCALAMMVFSKSFSVLRSAVTPRVMPPTIDLVRVNSRLTVFGLLGG
MLBr_02143|M.leprae_Br4923          MVLYPCALAMMVLSKSFSVLRSAVTPRVMPPSIDLVRVNSRLTVFGLLGG
MAV_1005|M.avium_104                MVLYPCALAMMVLSKSFSVLRSAVTPRVMPPSIDLVRVNSRLTMFGLLGG
MAB_0875c|M.abscessus_ATCC_199      WVLYPCALSMLVLSKSFGVLRGAVTPRVLPPTIDLVRVNSRLTTFGLVGG
                                     *******.*:*:****.***.*:****:**:*********** ***:**

Mflv_1711|M.gilvum_PYR-GCK          TMIGGGIAAAAEYGFQ-LFQMPGALYVVVAVTVAGAVLAMRIPKWVEVTE
Mvan_5040|M.vanbaalenii_PYR-1       TMIGGGIAAAAEWGFQ-LFQMPGALYVVVAVTIGGAVLAMRIPKWVEVTA
MSMEG_5693|M.smegmatis_MC2_155      TVAGGGVAAGAEYLFG-LVHLPGALYVIVAVSVAGAVLSMRIPKWVEVTE
TH_1066|M.thermoresistible__bu      TMLGGAVAAAAEYVFN-LFELPGALYVIVAVSLAGAVLSMRIPRWVEVTE
MMAR_4656|M.marinum_M               TMAGGAVAAGVEFACTRLFELPGALFVVVAVTVAGALLSMRIPRWVEVTA
MUL_0274|M.ulcerans_Agy99           TMAGGAVAAGVEFACTRLFELPGALFVVVAVTVAGALLSMRIPRWVEVTA
Mb0900c|M.bovis_AF2122/97           TIAGGAIAAGVEFVCTHLFQLPGALFVVVAITIAGASLSMRIPRWVEVTS
Rv0876c|M.tuberculosis_H37Rv        TIAGGAIAAGVEFVCTHLFQLPGALFVVVAITIAGASLSMRIPRWVEVTS
MLBr_02143|M.leprae_Br4923          TIAGGAIAAGVEFVCAHLFKLPGALFVVAAITISGALLSMRIPRWVEVTA
MAV_1005|M.avium_104                TIVGGAIAGGVEFVCTHLFKLPGALFVVVAVTVAGASLSMRIPRWVEVTA
MAB_0875c|M.abscessus_ATCC_199      TIVGGAIAAGCELAFTRLLHLPGALFVVIAVTAVGAWASMRIPKWVEVTA
                                    *: **.:*.. *     *..:****:*: *::  **  :****:***** 

Mflv_1711|M.gilvum_PYR-GCK          GEVPATLSYHGATEMLPREP-AAATGR-------ARQPLGRNIITSLWGN
Mvan_5040|M.vanbaalenii_PYR-1       GEVPTTLSYHGQTEGLRREPHGAVSAK-------TRQPLGRNIITALWGN
MSMEG_5693|M.smegmatis_MC2_155      GEVPTTLSYHGGPGELRRPEHPDTTGKPDKP-QSVRQPMGRNTITALWGN
TH_1066|M.thermoresistible__bu      GEVPATLTYHG---DLRRHPDQRRHSG------AARQPMGRNTITALWGN
MMAR_4656|M.marinum_M               GEVPATLSYHRDRGRQRRSWPEEVKNLS----GALRQPLGRNIITSLWGN
MUL_0274|M.ulcerans_Agy99           GEVPATLSYHRDRGRQRRSWPEEVKNLS----GALRQPLGRNIITSLWGN
Mb0900c|M.bovis_AF2122/97           GEVPATLSYHRDRGRLRRRWPEEVKNLG----GTLRQPLGRNIITSLWGN
Rv0876c|M.tuberculosis_H37Rv        GEVPATLSYHRDRGRLRRRWPEEVKNLG----GTLRQPLGRNIITSLWGN
MLBr_02143|M.leprae_Br4923          GEIPATLSYRLHRKPLRQSWPEEVKKVS----GRLRQPLGRNIITSLWGN
MAV_1005|M.avium_104                GEVPATLSYRRDSEPLRRRWPEEVKNVPKKATATLRQPLGRNIITSLWGN
MAB_0875c|M.abscessus_ATCC_199      GEVPTTFGYHGDDGEHPTILLRRSHKQP----EKVRQPLGRNIITSLWGN
                                    **:*:*: *:                         ***:*** **:****

Mflv_1711|M.gilvum_PYR-GCK          CTVKVMVGFLFLYPAFVAKAHDASGWEQLRILGMIGAAAAIGNFGGNFTA
Mvan_5040|M.vanbaalenii_PYR-1       CTVKVMVGFLFLYPAFVAKAHDASGWEQLRILGMIGAAAAVGNFAGNFTA
MSMEG_5693|M.smegmatis_MC2_155      CTIKVMVGFLFLYPAFVAKSHDASGWEQLLILGIIGAAAGIGNFAGNMTA
TH_1066|M.thermoresistible__bu      CTIKLMVGFLFLYPAFVAKSHEATGLEQLMILGLIGAAAAVGNFIGNFTA
MMAR_4656|M.marinum_M               CTIKVMVGFLFLYPAFVAKAHDANGWVQLGMLGLIGAAAAIGNFAGNFAS
MUL_0274|M.ulcerans_Agy99           CTIKVMVGFLFLYPAFVAKAHDANGWVQLGMLGLIGAAAAIGNFAGNFAS
Mb0900c|M.bovis_AF2122/97           CTIKVMVGFLFLYPAFVAKAHEANGWVQLGMLGLIGAAAAVGNFAGNFTS
Rv0876c|M.tuberculosis_H37Rv        CTIKVMVGFLFLYPAFVAKAHEANGWVQLGMLGLIGAAAAVGNFAGNFTS
MLBr_02143|M.leprae_Br4923          CTIKVMVGFLFLYPAFVAKEHQANGWVQLGMLGLIGTAAAIGNFAGNFTS
MAV_1005|M.avium_104                CTIKVMVGFLFLYPAFVAKAHQANGWAQLAMLGMIGAAAGVGNFVGNFTS
MAB_0875c|M.abscessus_ATCC_199      STIKVMVGFLTLYPAFVAKSHDAHGFQQLAMLGMVGAAAGIGNFAGNATS
                                    .*:*:***** ******** *:* *  ** :**::*:**.:*** ** ::

Mflv_1711|M.gilvum_PYR-GCK          ARLKLGHPARLVVRCAIAVTVVALATALTGNLFVAAAATLVTSAASAIAK
Mvan_5040|M.vanbaalenii_PYR-1       ARLKLGHPARLVVRCATAVTVMALATALSGNLLVAAAATLVTSGASAIAK
MSMEG_5693|M.smegmatis_MC2_155      ARLKLGHPAQMVVRLAIVVTVFALLAALTGKLLVAALATLVTSGASAIAK
TH_1066|M.thermoresistible__bu      ARLELGHPAQLVVRAAIAVTIGALATAVTGELLVAALATLITSGASAIAK
MMAR_4656|M.marinum_M               ARLQLGRPAVLVVRCTVVVTAFALAAAVAGNLVTAAIATLVTSGSSAIAK
MUL_0274|M.ulcerans_Agy99           ARLQLGRPAVLVVRCTMVVTAFALAAAVAGNLVTAAIATLVTSASSAIAK
Mb0900c|M.bovis_AF2122/97           ARLQLGRPAVLVVRCTVLVTVLAIAAAVAGSLAATAIATLITAGSSAIAK
Rv0876c|M.tuberculosis_H37Rv        ARLQLGRPAVLVVRCTVLVTVLAIAAAVAGSLAATAIATLITAGSSAIAK
MLBr_02143|M.leprae_Br4923          ARLQLGRPAVLVVRCTIAVTVLALAASVAGNLLMTTIATLITSGSSAIAK
MAV_1005|M.avium_104                ARLKLGRPAVLVVRCTVAVTAVALAASVAGNLMLAVIATLVTSGASAIAK
MAB_0875c|M.abscessus_ATCC_199      ARLKLGRPALLVVRCASAVTVVALAAAVTGVLAVVVVATLVTSAVSAIAK
                                    ***:**:** :*** :  **  *: ::::* *  .. ***:*:. *****

Mflv_1711|M.gilvum_PYR-GCK          ASLDASIQDDLPEESRASGFGRSESLLQLAWVAGGATGVLIYTELYAGFT
Mvan_5040|M.vanbaalenii_PYR-1       ASLDASLQDDLPEESRASAFGRSESLLQLAWVAGGATGVLIYTELYAGFT
MSMEG_5693|M.smegmatis_MC2_155      ASLDASLQDDLPEASRASAFGRSESVLQLAWVAGGAIGVLIYTDLSVGFT
TH_1066|M.thermoresistible__bu      ASLDASLQDDLPEQSRASAFGRSESLLQLAWVAGGATGVLVYTELWIGFT
MMAR_4656|M.marinum_M               ASLDASLQHDLPEESRASGFGRSESTLQLAWVLGGAVGVLIYTDLWIGFT
MUL_0274|M.ulcerans_Agy99           ASLDASLQHDLPEESRASGFGRSESTLQLAWVLGGAVGVLIYTDLWIGFT
Mb0900c|M.bovis_AF2122/97           ASLDASLQHDLPEESRASGFGRSESTLQLAWVLGGAVGVLVYTELWVGFT
Rv0876c|M.tuberculosis_H37Rv        ASLDASLQHDLPEESRASGFGRSESTLQLAWVLGGAVGVLVYTELWVGFT
MLBr_02143|M.leprae_Br4923          ASLDASLQNDLPEESRASGFGRSESTLQLAWVLGGALGVMVYTDLWVGFT
MAV_1005|M.avium_104                ASLDAALQDDLPEESRASGFGRSESTLQLAWVLGGALGVLVYTELWVGFT
MAB_0875c|M.abscessus_ATCC_199      ASLDASLQDDLPEESRASAFGRSEALLQLSWVLGGAIGVMIYTDLWVGFT
                                    *****::*.**** ****.*****: ***:** *** **::**:*  ***

Mflv_1711|M.gilvum_PYR-GCK          AITAILILGLAQTVLSYRGESLVPGLGGNRPVHAEQEGVRTD---AVVTR
Mvan_5040|M.vanbaalenii_PYR-1       TITAILILGLAQTVLSYRGESLVPGFGGNRPVLAEQEGVWTD---AAVTR
MSMEG_5693|M.smegmatis_MC2_155      TITAVLILGLAQTIVSYRGESLIPGFGGNRPVLAEREGTMAW---GAR--
TH_1066|M.thermoresistible__bu      TISAILILGLAQTIVSYRGDSLIPGFGGNRPVLAEPEGRNDH---PAFTP
MMAR_4656|M.marinum_M               TVSALLILGLAQTIVSFRGDSLIPGLGGNRPVMAEQETTRRGSATAGVGP
MUL_0274|M.ulcerans_Agy99           TVSALLILGLAQTIVSFRGDSLIPGLGGNRPVMAEQETTRRGTATAGVGP
Mb0900c|M.bovis_AF2122/97           AVSALLILGLAQTIVSFRGDSLIPGLGGNRPVMAEQETTRRG---AAVAP
Rv0876c|M.tuberculosis_H37Rv        AVSALLILGLAQTIVSFRGDSLIPGLGGNRPVMAEQETTRRG---AAVAP
MLBr_02143|M.leprae_Br4923          AVSALLILGLAQTVVSFRGDSLIPGLGGNRPVMIEQESMRRA---AAVSP
MAV_1005|M.avium_104                AVTALLILGLAQTLVSFRGNSLIPGLGGNRPIMVEQEGARRGVGRPAVVA
MAB_0875c|M.abscessus_ATCC_199      VISAVLILGLAQTLASFRGVSLIPGLGGNRPVMAEQEGGKVHA-------
                                    .::*:********: *:** **:**:*****:  * *             

Mflv_1711|M.gilvum_PYR-GCK          E
Mvan_5040|M.vanbaalenii_PYR-1       E
MSMEG_5693|M.smegmatis_MC2_155      -
TH_1066|M.thermoresistible__bu      R
MMAR_4656|M.marinum_M               Q
MUL_0274|M.ulcerans_Agy99           Q
Mb0900c|M.bovis_AF2122/97           Q
Rv0876c|M.tuberculosis_H37Rv        Q
MLBr_02143|M.leprae_Br4923          Q
MAV_1005|M.avium_104                E
MAB_0875c|M.abscessus_ATCC_199      -