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M. smegmatis MC2 155 MSMEG_6922 (-)

annotation: transporter, major facilitator family protein
coordinates: 6964262 - 6965557
length: 431

VIFVVDARAPIALWRSLRAMTEFRRLLELRAVSQFGDGLFQAGLAGAILFNVERAAGPWQIAGSFAVLFL
PYSALGPFAGALLDRWDRRLVMIGANLGRLLLVVLVGVLLALGAGDLEILCCALIINGFTRFVSSGLSAA
LPDVVPRGQVVAMNSVATATGAAAAFLGANFMLLPRWLFGAGDAGASVVIFIVLIPVALALWLSVRFGPH
VLGPHESKRAIHGSVAYAVSTGWLHGARTVASVRTVAATLGGLAAHRAAFGINTLIVLVLVRHTDTPTQV
AGVGLGTAVVFVGATGAGTFLATLVMPAVVARFGRYATANGALAFAALVQAVALSLHLPVMLVCGFLLGA
AGQFVKLCADSAMQIDVDDALRGHVFTVQDALFWMSFVCAIAVAALVIAPDGHSPGLVAAGSVIYLAGLG
LHAFVASPRRA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_6922--100% (431)transporter, major facilitator family protein
M. smegmatis MC2 155MSMEG_6390-3e-0922.28% (386) transporter, major facilitator family protein
M. smegmatis MC2 155MSMEG_5674-5e-0927.98% (386) membrane transport protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0038c-1e-15766.11% (419) integral membrane protein
M. gilvum PYR-GCKMflv_0849-1e-16469.05% (420) major facilitator transporter
M. tuberculosis H37RvRv0037c-1e-15766.11% (419) integral membrane protein
M. leprae Br4923MLBr_02143-6e-0521.45% (387) hypothetical protein MLBr_02143
M. abscessus ATCC 19977MAB_4929-1e-13057.73% (414) hypothetical protein MAB_4929
M. marinum MMMAR_0052-1e-15464.44% (419) integral membrane protein
M. avium 104MAV_0051-1e-15363.18% (421) transporter, major facilitator family protein
M. thermoresistible (build 8)TH_1066-7e-0621.24% (372) POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN
M. ulcerans Agy99MUL_0051-1e-15363.96% (419) integral membrane protein
M. vanbaalenii PYR-1Mvan_6058-1e-17070.85% (422) major facilitator superfamily transporter

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0849|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_6058|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_6922|M.smegmatis_MC2_155      --------------------------------------------------
Mb0038c|M.bovis_AF2122/97           --------------------------------------------------
Rv0037c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0052|M.marinum_M               --------------------------------------------------
MUL_0051|M.ulcerans_Agy99           --------------------------------------------------
MAV_0051|M.avium_104                --------------------------------------------------
MAB_4929|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02143|M.leprae_Br4923          MSGRRRNHPGRLASIPGLRTRTGSRNQHPGIANYPADSSDFRPAQQRRAL
TH_1066|M.thermoresistible__bu      ------------------------------MANYPSDDPAPRRPGRPKAP
                                                                                      

Mflv_0849|M.gilvum_PYR-GCK          ---------------------------------------MANERSPVAYL
Mvan_6058|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_6922|M.smegmatis_MC2_155      --------------------------------------------------
Mb0038c|M.bovis_AF2122/97           --------------------------------------------------
Rv0037c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0052|M.marinum_M               --------------------------------------------------
MUL_0051|M.ulcerans_Agy99           --------------------------------------------------
MAV_0051|M.avium_104                --------------------------------------------------
MAB_4929|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02143|M.leprae_Br4923          EQREQQAGQLDPARRSPSMPSANRYLPPLGQQQSEPQHNSAPPCGPYPGE
TH_1066|M.thermoresistible__bu      PSANRWLPPLDEDR--PTFDRGAGEPPPRGYRSTG---------RPRSDE
                                                                                      

Mflv_0849|M.gilvum_PYR-GCK          YCGSGSARPHPPQDVTPVPDDRAPRTSWRAVQALPQFRRLLELRAVSQFA
Mvan_6058|M.vanbaalenii_PYR-1       -----------------MPDDRAPRTLWRSVRALPEFRRLLELRAVSQFG
MSMEG_6922|M.smegmatis_MC2_155      --------------MIFVVDARAPIALWRSLRAMTEFRRLLELRAVSQFG
Mb0038c|M.bovis_AF2122/97           -----MPRVEVGLVIHSRMHARAPVDVWRSVRSLPDFWRLLQVRVASQFG
Rv0037c|M.tuberculosis_H37Rv        -----MPRVEVGLVIHSRMHARAPVDVWRSVRSLPDFWRLLQVRVASQFG
MMAR_0052|M.marinum_M               ------------------MHASAPVELWRSVRSLPDFWRLLQVRIASQFG
MUL_0051|M.ulcerans_Agy99           ------------------MHASAPVELWRSVRSLPDFWRLLQVRIASQFG
MAV_0051|M.avium_104                -------------MIPTRMQSSAPVEIWRSVRALPDFWRLLQVRVASQFG
MAB_4929|M.abscessus_ATCC_1997      -----------------MTARHSPLSLWRAIHDLPDFGRLVWVRLLTQFS
MLBr_02143|M.leprae_Br4923          RIKVTRAAAQRSREMGYRMYWMVQRAATADGADKSGLTALTWPVVTNFAV
TH_1066|M.thermoresistible__bu      RITVTRAAAQRSREMGSRMYGLVHRAATADGADKSGLTALTWPVVANFAV
                                                                      . :  *      .   

Mflv_0849|M.gilvum_PYR-GCK          EGLFQAGIAGALLFNPEREADPWAIAGAFAALFLPYSLLGPFAGALLDRW
Mvan_6058|M.vanbaalenii_PYR-1       DGLFQAGIAGAILFNPEREAEPWAIAAAFAVLFLPYSLLGPFAGALLDRW
MSMEG_6922|M.smegmatis_MC2_155      DGLFQAGLAGAILFNVERAAGPWQIAGSFAVLFLPYSALGPFAGALLDRW
Mb0038c|M.bovis_AF2122/97           DGLFQAGLAGALLFNPDRAADPMAIAGAFAVLFLPYSLLGPFAGALMDRW
Rv0037c|M.tuberculosis_H37Rv        DGLFQAGLAGALLFNPDRAADPMAIAGAFAVLFLPYSLLGPFAGALMDRW
MMAR_0052|M.marinum_M               DGLFQAGLAGALLFNPDRAADPMAIARAFAVLFLPYSLLGPFAGALMDRW
MUL_0051|M.ulcerans_Agy99           DGLFQAGLAGALLFNPDRAADPMAIARAFAVLFLPYSLLGPFAGALMDRW
MAV_0051|M.avium_104                DGLFQAALAGALLFNPDRAADPLAIARAFTVLFLPYSLLGPFAGALMDRW
MAB_4929|M.abscessus_ATCC_1997      DGLFQAGLAGALLFNPEREAEPWAIAGAFAVLFLPYSAIGPFAGALLDRW
MLBr_02143|M.leprae_Br4923          DSAMAVALANTLFFAAASGESKSKVALYLLITIAPFAVIAPLIGPALDRL
TH_1066|M.thermoresistible__bu      DAAMAVALANTLFFAAATGESKARVALYLLITIAPFAVIAPLIGPALDRL
                                    :. : ..:*.:::*          :*  :   : *:: :.*: *. :** 

Mflv_0849|M.gilvum_PYR-GCK          DR--RLVLIGANTGRVAIVLLVGVLLAAGAG---DIPILLSALVANGFTR
Mvan_6058|M.vanbaalenii_PYR-1       DR--RLVLIGANCGRLVVILVVGALLSAGLS---DIPILLSALLANGFTR
MSMEG_6922|M.smegmatis_MC2_155      DR--RLVMIGANLGRLLLVVLVGVLLALGAG---DLEILCCALIINGFTR
Mb0038c|M.bovis_AF2122/97           DR--RWVLVGANTGRLALIAGVGTILAVGAG---DVPLLVGALVANGLAR
Rv0037c|M.tuberculosis_H37Rv        DR--RWVLVGANTGRLALIAGVGTILAVGAG---DVPLLVGALVANGLAR
MMAR_0052|M.marinum_M               DR--RLVIVGANIGRLILIAGIGTILAFEAG---DLLLLFVALLANGLAR
MUL_0051|M.ulcerans_Agy99           DR--RLVIVGANIGRLILIAGIGTILAFEAG---DLLLLFVALLANGLAR
MAV_0051|M.avium_104                DR--RLVLVGANVGRLVLIAAIGTILAVRAG---DLSLLLGALFANGLAR
MAB_4929|M.abscessus_ATCC_1997      DR--RAVLICANLIRVLLVALVGFELAFSAD---DVVLLLGALIVNGVTR
MLBr_02143|M.leprae_Br4923          QHGRRVALATSFVLRTGLATLLIMNYDGATGSYPSMVLYPCALAMMVLSK
TH_1066|M.thermoresistible__bu      QHGRRVALATSFGLRTALVVVLIANYDGATGSFPSWVLYPCALAMMVLSK
                                    ::  * .:  :   *  :   :        .   .  :   **    .::

Mflv_0849|M.gilvum_PYR-GCK          FVSSGLSAALPHVVP-REQVIPMNSVANLISSIGAFAGAVFMLGPRWLFG
Mvan_6058|M.vanbaalenii_PYR-1       FVSSGLSAALPHVVP-RDQVIAMNSVATATTSIAAFAGAIFMLLPRWLFG
MSMEG_6922|M.smegmatis_MC2_155      FVSSGLSAALPDVVP-RGQVVAMNSVATATGAAAAFLGANFMLLPRWLFG
Mb0038c|M.bovis_AF2122/97           FVASGLSAALPHVVP-REQVVTMNSVAIASGAVSAFLGANFMLLPRWLLG
Rv0037c|M.tuberculosis_H37Rv        FVASGLSAALPHVVP-REQVVTMNSVAIASGAVSAFLGANFMLLPRWLLG
MMAR_0052|M.marinum_M               FVASGLSASLPHVVP-REQVVTMNSVATASGAVAAFVGANFMLLPRWLAG
MUL_0051|M.ulcerans_Agy99           FVASGLSASLPHVVP-REQVVTMNSVATASGAVAAFVGANFMLLPRWLAG
MAV_0051|M.avium_104                FVGSGLSASLPHVVP-REQVVTMNAVATAAGAVAAFLGANFMLVPRFLFG
MAB_4929|M.abscessus_ATCC_1997      FVTSGLSAALPHVVP-RDQVATMNSVATAVGATATFIGANFMLMLRAAFG
MLBr_02143|M.leprae_Br4923          SFSVLRSAVTPRVMPPSIDLVRVNSRLTVFGLLGGTIAGGAIAAGVEFVC
TH_1066|M.thermoresistible__bu      SFSVLRSAMTPRVLPPTIDLVRVNSRLTMFGLLGGTMLGGAVAAAAEYVF
                                     .    **  * *:*   ::  :*:        .    .  :        

Mflv_0849|M.gilvum_PYR-GCK          AGDSGASITILMVTVPVGLALWLSMRFPPRLLGPDDSKRAVHGS-----V
Mvan_6058|M.vanbaalenii_PYR-1       AGDSGASVIIFMVAVPVSVALWLSMRFPPRLLGPDDSARAVHGS-----V
MSMEG_6922|M.smegmatis_MC2_155      AGDAGASVVIFIVLIPVALALWLSVRFGPHVLGPHESKRAIHGS-----V
Mb0038c|M.bovis_AF2122/97           SGDEGASAIVFLVAIPVSIALLWSLRFGPRVLGPDDTERAIHGS-----A
Rv0037c|M.tuberculosis_H37Rv        SGDEGASAIVFLVAIPVSIALLWSLRFGPRVLGPDDTERAIHGS-----A
MMAR_0052|M.marinum_M               GGDHGAAAVIFTAMIPVAISLLLALRFAPRVLGPDDTKRAIHGS-----A
MUL_0051|M.ulcerans_Agy99           GGDHGAAAVIFTAMIPVAISLLLALRFAPRVLGPDDTKRAIHGS-----A
MAV_0051|M.avium_104                AGDRGAAAIVFLTVVPVSIALLLSWRFAPRALGPDDTWRAIHGP-----V
MAB_4929|M.abscessus_ATCC_1997      AGDLGSATVIFLVIVPTTAAAWVASGFPGDRLGPDDSVRAVHGS-----A
MLBr_02143|M.leprae_Br4923          AHLFKLPGALFVVAAITISGALLSMRIPRWVEVTAGEIPATLSYRLHRKP
TH_1066|M.thermoresistible__bu      N-LFELPGALYVIVAVSLAGAVLSMRIPRWVEVTEGEVPATLTY---HGD
                                          .  :         .   :  :      .     *          

Mflv_0849|M.gilvum_PYR-GCK          MYAVATGWLYGARTVLAVPTAASTLAGLAAHRMVFGINTLLMLVIVRHTE
Mvan_6058|M.vanbaalenii_PYR-1       LYAVATGWLHGARTVLAVPSVSSTLSGLAAHRMVFGVNTLLVLVMVRHTE
MSMEG_6922|M.smegmatis_MC2_155      AYAVSTGWLHGARTVASVRTVAATLGGLAAHRAAFGINTLIVLVLVRHTD
Mb0038c|M.bovis_AF2122/97           VYAVVTGWLHGARTVVQLPTVAAGLSGLAAHRMVVGINSLLILLLVRHVT
Rv0037c|M.tuberculosis_H37Rv        VYAVVTGWLHGARTVVQLPTVAAGLSGLAAHRMVVGINSLLILLLVRHVT
MMAR_0052|M.marinum_M               VYAVITGWMHGVRTVVQLPTVAAALSGLAAHRMVVGVNSLLILLLVHHMR
MUL_0051|M.ulcerans_Agy99           VYAVITGWMHGVRTVVQIPTVAAALSGLAAHRMVVGVNSLLILLLVHHMR
MAV_0051|M.avium_104                LYAVITGWLHGARTVAQRPTVAATLSGLAAHRMVVGINSLLVLLLVHHLP
MAB_4929|M.abscessus_ATCC_1997      FYAVATGWLHGARTIVGTPSVFDALIGLAAHRMVFGVNTLLVLVLVRSNE
MLBr_02143|M.leprae_Br4923          LRQSWPEEVKKVSGRLRQPLGRNIITSLWGNCTIKVMVGFLFLYPAFVAK
TH_1066|M.thermoresistible__bu      LRR--HPDQRRHSGAARQPMGRNTITALWGNCTIKLMVGFLFLYPAFVAK
                                                            : .* .:     :  ::.*  .    

Mflv_0849|M.gilvum_PYR-GCK          TATVAG---FGTTVLFVIAGGAGQFVATIATPALVTRWGRYAAPNGALAL
Mvan_6058|M.vanbaalenii_PYR-1       AATVAG---FGTTVLFVSAGGAGQFLATVVTPTLVKKWGRYATPNGALAF
MSMEG_6922|M.smegmatis_MC2_155      TPTQVAGVGLGTAVVFVGATGAGTFLATLVMPAVVARFGRYATANGALAF
Mb0038c|M.bovis_AF2122/97           ARAVGG---LGTALLFFAATGLGAFLANVLTPTAIRRWGRYATANGALAA
Rv0037c|M.tuberculosis_H37Rv        ARAVGG---LGTALLFFAATGLGAFLANVLTPTAIRRWGRYATANGALAA
MMAR_0052|M.marinum_M               DVDVEG---LGTALLFFAATGLGAFLANVLTPGLIRRWGRYATTNGALAA
MUL_0051|M.ulcerans_Agy99           DVDVEG---LGTALLFFAATGLGAFLANVLTPGLIRRWGRYATTNGALAA
MAV_0051|M.avium_104                GLEGGG---FGTALLFFGAAGLGAFLANVLTPPAIRRWGRYATANGALAA
MAB_4929|M.abscessus_ATCC_1997      S-VFAG---IGAAALFLACTGIGSFLGTVSTPALLRRFGRGRTLGMALGG
MLBr_02143|M.leprae_Br4923          EHQANGWVQLGMLGLIGTAAAIGNFAGNFTSARLQLGRPAVLVVRCTIAV
TH_1066|M.thermoresistible__bu      SHEATGLEQLMILGLIGAAAAVGNFIGNFTAARLELGHPAQLVVRAAIAV
                                         .   :    ::  . . * * ...  .          .   ::. 

Mflv_0849|M.gilvum_PYR-GCK          AAVVQVCAATLQLPVMIVCGFVLGAAGQVVKLCADSAMQIDVDDALRGHM
Mvan_6058|M.vanbaalenii_PYR-1       AAAVQLCGATLNLPVMIVCGFLLGAAGQVVKLCADTAMQIDVEDALRGHL
MSMEG_6922|M.smegmatis_MC2_155      AALVQAVALSLHLPVMLVCGFLLGAAGQFVKLCADSAMQIDVDDALRGHV
Mb0038c|M.bovis_AF2122/97           AATIQVAAAGLLVPVMVVCGFLLGVAGQVVKLCADSAMQMDVDDALRGHV
Rv0037c|M.tuberculosis_H37Rv        AATIQVAAAGLLVPVMVVCGFLLGVAGQVVKLCADSAMQMDVDDALRGHV
MMAR_0052|M.marinum_M               AAVIQLAGAGLLLPVMVVCGFLLGVAGQVVKLCADSAMQIDVDDALRGHV
MUL_0051|M.ulcerans_Agy99           AAVTQLAGAGLLLPVMVVCGFLLGVAGQVVKLCADSAMQIDVDGALRGHV
MAV_0051|M.avium_104                SAIIEVAGAELLLPVMVVCGFLLGVTGQMVKLCADSAMQMDVDDALRGHV
MAB_4929|M.abscessus_ATCC_1997      AVVLQLIASGLYIPILLASAFGLGMAGQVIKLCADVGMQTDVDDALRGHV
MLBr_02143|M.leprae_Br4923          TVLALAASVAGNLLMTTIATLITSGSSAIAKASLDASLQNDLPEESRASG
TH_1066|M.thermoresistible__bu      TIGALATAVTGELLVAALATLITSGASAIAKASLDASLQDDLPEQSRASA
                                    :      .    : :   . :  . :. . * . * .:* *:    *.  

Mflv_0849|M.gilvum_PYR-GCK          FAVQDSLFWVAFIVAITGAAAVIPADGHSPALAVAGTGLYLAGLAAHAV-
Mvan_6058|M.vanbaalenii_PYR-1       FAVQDALFWLAFIVAISAAAFVIPPDGRSVGLAVAGVGTYLAGLAVHAT-
MSMEG_6922|M.smegmatis_MC2_155      FTVQDALFWMSFVCAIAVAALVIAPDGHSPGLVAAGSVIYLAGLGLHAF-
Mb0038c|M.bovis_AF2122/97           FAVQDALFWVSYILSITVAAALIPEHGHAPVFVLFGSAIYLAGLVVHTI-
Rv0037c|M.tuberculosis_H37Rv        FAVQDALFWVSYILSITVAAALIPEHGHAPVFVLFGSAIYLAGLVVHTI-
MMAR_0052|M.marinum_M               FAVQDALFWVSYIVSVTVAAALIPDDGRAPVFVLVGSVIYLIGLCVHSI-
MUL_0051|M.ulcerans_Agy99           FAVQDALFWVSYIVSVTVAAALIPDDGRAPVFVLVGSLIYLLGLCVHSI-
MAV_0051|M.avium_104                FAVQDALFWVAFIVAITVAGMVIPDDGHAPVFALFGSVLYLVGLAVHGI-
MAB_4929|M.abscessus_ATCC_1997      FAVQDSLFWVTFTGAMAVGAAFIT---HAHWLAFSGAMIYLAGLIVHMTR
MLBr_02143|M.leprae_Br4923          FGRSESTLQLAWVLGGALGVMVYTDLWVGFTAVSALLILGLAQTVVSFRG
TH_1066|M.thermoresistible__bu      FGRSESLLQLAWVAGGATGVLVYTELWIGFTTISAILILGLAQTIVSYRG
                                    *  .:: : :::  . : .  . .    .           *         

Mflv_0849|M.gilvum_PYR-GCK          -----------------MGRRGR-RG-------------
Mvan_6058|M.vanbaalenii_PYR-1       -----------------VGRRGRPRG-------------
MSMEG_6922|M.smegmatis_MC2_155      -----------------VASPRRA---------------
Mb0038c|M.bovis_AF2122/97           -----------------VGRR--GQPVIGR---------
Rv0037c|M.tuberculosis_H37Rv        -----------------VGRR--GQPVIGR---------
MMAR_0052|M.marinum_M               -----------------VGRRSSAANVEGG---------
MUL_0051|M.ulcerans_Agy99           -----------------VGRRSSASNVEGC---------
MAV_0051|M.avium_104                -----------------VGRR--GE--------------
MAB_4929|M.abscessus_ATCC_1997      TLWPSTLDTGSLPTQPNAGSLPTQPNPEGQARDLDR---
MLBr_02143|M.leprae_Br4923          DSLIPG----------LGGNRPVMIEQESMRRAAAVSPQ
TH_1066|M.thermoresistible__bu      DSLIPG----------FGGNRPVLAEPEGRNDHPAFTPR
                                                      .