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VIFVVDARAPIALWRSLRAMTEFRRLLELRAVSQFGDGLFQAGLAGAILFNVERAAGPWQIAGSFAVLFL PYSALGPFAGALLDRWDRRLVMIGANLGRLLLVVLVGVLLALGAGDLEILCCALIINGFTRFVSSGLSAA LPDVVPRGQVVAMNSVATATGAAAAFLGANFMLLPRWLFGAGDAGASVVIFIVLIPVALALWLSVRFGPH VLGPHESKRAIHGSVAYAVSTGWLHGARTVASVRTVAATLGGLAAHRAAFGINTLIVLVLVRHTDTPTQV AGVGLGTAVVFVGATGAGTFLATLVMPAVVARFGRYATANGALAFAALVQAVALSLHLPVMLVCGFLLGA AGQFVKLCADSAMQIDVDDALRGHVFTVQDALFWMSFVCAIAVAALVIAPDGHSPGLVAAGSVIYLAGLG LHAFVASPRRA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_6922 | - | - | 100% (431) | transporter, major facilitator family protein |
M. smegmatis MC2 155 | MSMEG_6390 | - | 3e-09 | 22.28% (386) | transporter, major facilitator family protein |
M. smegmatis MC2 155 | MSMEG_5674 | - | 5e-09 | 27.98% (386) | membrane transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0038c | - | 1e-157 | 66.11% (419) | integral membrane protein |
M. gilvum PYR-GCK | Mflv_0849 | - | 1e-164 | 69.05% (420) | major facilitator transporter |
M. tuberculosis H37Rv | Rv0037c | - | 1e-157 | 66.11% (419) | integral membrane protein |
M. leprae Br4923 | MLBr_02143 | - | 6e-05 | 21.45% (387) | hypothetical protein MLBr_02143 |
M. abscessus ATCC 19977 | MAB_4929 | - | 1e-130 | 57.73% (414) | hypothetical protein MAB_4929 |
M. marinum M | MMAR_0052 | - | 1e-154 | 64.44% (419) | integral membrane protein |
M. avium 104 | MAV_0051 | - | 1e-153 | 63.18% (421) | transporter, major facilitator family protein |
M. thermoresistible (build 8) | TH_1066 | - | 7e-06 | 21.24% (372) | POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN |
M. ulcerans Agy99 | MUL_0051 | - | 1e-153 | 63.96% (419) | integral membrane protein |
M. vanbaalenii PYR-1 | Mvan_6058 | - | 1e-170 | 70.85% (422) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_0849|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6058|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_6922|M.smegmatis_MC2_155 -------------------------------------------------- Mb0038c|M.bovis_AF2122/97 -------------------------------------------------- Rv0037c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0052|M.marinum_M -------------------------------------------------- MUL_0051|M.ulcerans_Agy99 -------------------------------------------------- MAV_0051|M.avium_104 -------------------------------------------------- MAB_4929|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02143|M.leprae_Br4923 MSGRRRNHPGRLASIPGLRTRTGSRNQHPGIANYPADSSDFRPAQQRRAL TH_1066|M.thermoresistible__bu ------------------------------MANYPSDDPAPRRPGRPKAP Mflv_0849|M.gilvum_PYR-GCK ---------------------------------------MANERSPVAYL Mvan_6058|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_6922|M.smegmatis_MC2_155 -------------------------------------------------- Mb0038c|M.bovis_AF2122/97 -------------------------------------------------- Rv0037c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0052|M.marinum_M -------------------------------------------------- MUL_0051|M.ulcerans_Agy99 -------------------------------------------------- MAV_0051|M.avium_104 -------------------------------------------------- MAB_4929|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02143|M.leprae_Br4923 EQREQQAGQLDPARRSPSMPSANRYLPPLGQQQSEPQHNSAPPCGPYPGE TH_1066|M.thermoresistible__bu PSANRWLPPLDEDR--PTFDRGAGEPPPRGYRSTG---------RPRSDE Mflv_0849|M.gilvum_PYR-GCK YCGSGSARPHPPQDVTPVPDDRAPRTSWRAVQALPQFRRLLELRAVSQFA Mvan_6058|M.vanbaalenii_PYR-1 -----------------MPDDRAPRTLWRSVRALPEFRRLLELRAVSQFG MSMEG_6922|M.smegmatis_MC2_155 --------------MIFVVDARAPIALWRSLRAMTEFRRLLELRAVSQFG Mb0038c|M.bovis_AF2122/97 -----MPRVEVGLVIHSRMHARAPVDVWRSVRSLPDFWRLLQVRVASQFG Rv0037c|M.tuberculosis_H37Rv -----MPRVEVGLVIHSRMHARAPVDVWRSVRSLPDFWRLLQVRVASQFG MMAR_0052|M.marinum_M ------------------MHASAPVELWRSVRSLPDFWRLLQVRIASQFG MUL_0051|M.ulcerans_Agy99 ------------------MHASAPVELWRSVRSLPDFWRLLQVRIASQFG MAV_0051|M.avium_104 -------------MIPTRMQSSAPVEIWRSVRALPDFWRLLQVRVASQFG MAB_4929|M.abscessus_ATCC_1997 -----------------MTARHSPLSLWRAIHDLPDFGRLVWVRLLTQFS MLBr_02143|M.leprae_Br4923 RIKVTRAAAQRSREMGYRMYWMVQRAATADGADKSGLTALTWPVVTNFAV TH_1066|M.thermoresistible__bu RITVTRAAAQRSREMGSRMYGLVHRAATADGADKSGLTALTWPVVANFAV . : * . Mflv_0849|M.gilvum_PYR-GCK EGLFQAGIAGALLFNPEREADPWAIAGAFAALFLPYSLLGPFAGALLDRW Mvan_6058|M.vanbaalenii_PYR-1 DGLFQAGIAGAILFNPEREAEPWAIAAAFAVLFLPYSLLGPFAGALLDRW MSMEG_6922|M.smegmatis_MC2_155 DGLFQAGLAGAILFNVERAAGPWQIAGSFAVLFLPYSALGPFAGALLDRW Mb0038c|M.bovis_AF2122/97 DGLFQAGLAGALLFNPDRAADPMAIAGAFAVLFLPYSLLGPFAGALMDRW Rv0037c|M.tuberculosis_H37Rv DGLFQAGLAGALLFNPDRAADPMAIAGAFAVLFLPYSLLGPFAGALMDRW MMAR_0052|M.marinum_M DGLFQAGLAGALLFNPDRAADPMAIARAFAVLFLPYSLLGPFAGALMDRW MUL_0051|M.ulcerans_Agy99 DGLFQAGLAGALLFNPDRAADPMAIARAFAVLFLPYSLLGPFAGALMDRW MAV_0051|M.avium_104 DGLFQAALAGALLFNPDRAADPLAIARAFTVLFLPYSLLGPFAGALMDRW MAB_4929|M.abscessus_ATCC_1997 DGLFQAGLAGALLFNPEREAEPWAIAGAFAVLFLPYSAIGPFAGALLDRW MLBr_02143|M.leprae_Br4923 DSAMAVALANTLFFAAASGESKSKVALYLLITIAPFAVIAPLIGPALDRL TH_1066|M.thermoresistible__bu DAAMAVALANTLFFAAATGESKARVALYLLITIAPFAVIAPLIGPALDRL :. : ..:*.:::* :* : : *:: :.*: *. :** Mflv_0849|M.gilvum_PYR-GCK DR--RLVLIGANTGRVAIVLLVGVLLAAGAG---DIPILLSALVANGFTR Mvan_6058|M.vanbaalenii_PYR-1 DR--RLVLIGANCGRLVVILVVGALLSAGLS---DIPILLSALLANGFTR MSMEG_6922|M.smegmatis_MC2_155 DR--RLVMIGANLGRLLLVVLVGVLLALGAG---DLEILCCALIINGFTR Mb0038c|M.bovis_AF2122/97 DR--RWVLVGANTGRLALIAGVGTILAVGAG---DVPLLVGALVANGLAR Rv0037c|M.tuberculosis_H37Rv DR--RWVLVGANTGRLALIAGVGTILAVGAG---DVPLLVGALVANGLAR MMAR_0052|M.marinum_M DR--RLVIVGANIGRLILIAGIGTILAFEAG---DLLLLFVALLANGLAR MUL_0051|M.ulcerans_Agy99 DR--RLVIVGANIGRLILIAGIGTILAFEAG---DLLLLFVALLANGLAR MAV_0051|M.avium_104 DR--RLVLVGANVGRLVLIAAIGTILAVRAG---DLSLLLGALFANGLAR MAB_4929|M.abscessus_ATCC_1997 DR--RAVLICANLIRVLLVALVGFELAFSAD---DVVLLLGALIVNGVTR MLBr_02143|M.leprae_Br4923 QHGRRVALATSFVLRTGLATLLIMNYDGATGSYPSMVLYPCALAMMVLSK TH_1066|M.thermoresistible__bu QHGRRVALATSFGLRTALVVVLIANYDGATGSFPSWVLYPCALAMMVLSK :: * .: : * : : . . : ** .:: Mflv_0849|M.gilvum_PYR-GCK FVSSGLSAALPHVVP-REQVIPMNSVANLISSIGAFAGAVFMLGPRWLFG Mvan_6058|M.vanbaalenii_PYR-1 FVSSGLSAALPHVVP-RDQVIAMNSVATATTSIAAFAGAIFMLLPRWLFG MSMEG_6922|M.smegmatis_MC2_155 FVSSGLSAALPDVVP-RGQVVAMNSVATATGAAAAFLGANFMLLPRWLFG Mb0038c|M.bovis_AF2122/97 FVASGLSAALPHVVP-REQVVTMNSVAIASGAVSAFLGANFMLLPRWLLG Rv0037c|M.tuberculosis_H37Rv FVASGLSAALPHVVP-REQVVTMNSVAIASGAVSAFLGANFMLLPRWLLG MMAR_0052|M.marinum_M FVASGLSASLPHVVP-REQVVTMNSVATASGAVAAFVGANFMLLPRWLAG MUL_0051|M.ulcerans_Agy99 FVASGLSASLPHVVP-REQVVTMNSVATASGAVAAFVGANFMLLPRWLAG MAV_0051|M.avium_104 FVGSGLSASLPHVVP-REQVVTMNAVATAAGAVAAFLGANFMLVPRFLFG MAB_4929|M.abscessus_ATCC_1997 FVTSGLSAALPHVVP-RDQVATMNSVATAVGATATFIGANFMLMLRAAFG MLBr_02143|M.leprae_Br4923 SFSVLRSAVTPRVMPPSIDLVRVNSRLTVFGLLGGTIAGGAIAAGVEFVC TH_1066|M.thermoresistible__bu SFSVLRSAMTPRVLPPTIDLVRVNSRLTMFGLLGGTMLGGAVAAAAEYVF . ** * *:* :: :*: . . : Mflv_0849|M.gilvum_PYR-GCK AGDSGASITILMVTVPVGLALWLSMRFPPRLLGPDDSKRAVHGS-----V Mvan_6058|M.vanbaalenii_PYR-1 AGDSGASVIIFMVAVPVSVALWLSMRFPPRLLGPDDSARAVHGS-----V MSMEG_6922|M.smegmatis_MC2_155 AGDAGASVVIFIVLIPVALALWLSVRFGPHVLGPHESKRAIHGS-----V Mb0038c|M.bovis_AF2122/97 SGDEGASAIVFLVAIPVSIALLWSLRFGPRVLGPDDTERAIHGS-----A Rv0037c|M.tuberculosis_H37Rv SGDEGASAIVFLVAIPVSIALLWSLRFGPRVLGPDDTERAIHGS-----A MMAR_0052|M.marinum_M GGDHGAAAVIFTAMIPVAISLLLALRFAPRVLGPDDTKRAIHGS-----A MUL_0051|M.ulcerans_Agy99 GGDHGAAAVIFTAMIPVAISLLLALRFAPRVLGPDDTKRAIHGS-----A MAV_0051|M.avium_104 AGDRGAAAIVFLTVVPVSIALLLSWRFAPRALGPDDTWRAIHGP-----V MAB_4929|M.abscessus_ATCC_1997 AGDLGSATVIFLVIVPTTAAAWVASGFPGDRLGPDDSVRAVHGS-----A MLBr_02143|M.leprae_Br4923 AHLFKLPGALFVVAAITISGALLSMRIPRWVEVTAGEIPATLSYRLHRKP TH_1066|M.thermoresistible__bu N-LFELPGALYVIVAVSLAGAVLSMRIPRWVEVTEGEVPATLTY---HGD . : . : : . * Mflv_0849|M.gilvum_PYR-GCK MYAVATGWLYGARTVLAVPTAASTLAGLAAHRMVFGINTLLMLVIVRHTE Mvan_6058|M.vanbaalenii_PYR-1 LYAVATGWLHGARTVLAVPSVSSTLSGLAAHRMVFGVNTLLVLVMVRHTE MSMEG_6922|M.smegmatis_MC2_155 AYAVSTGWLHGARTVASVRTVAATLGGLAAHRAAFGINTLIVLVLVRHTD Mb0038c|M.bovis_AF2122/97 VYAVVTGWLHGARTVVQLPTVAAGLSGLAAHRMVVGINSLLILLLVRHVT Rv0037c|M.tuberculosis_H37Rv VYAVVTGWLHGARTVVQLPTVAAGLSGLAAHRMVVGINSLLILLLVRHVT MMAR_0052|M.marinum_M VYAVITGWMHGVRTVVQLPTVAAALSGLAAHRMVVGVNSLLILLLVHHMR MUL_0051|M.ulcerans_Agy99 VYAVITGWMHGVRTVVQIPTVAAALSGLAAHRMVVGVNSLLILLLVHHMR MAV_0051|M.avium_104 LYAVITGWLHGARTVAQRPTVAATLSGLAAHRMVVGINSLLVLLLVHHLP MAB_4929|M.abscessus_ATCC_1997 FYAVATGWLHGARTIVGTPSVFDALIGLAAHRMVFGVNTLLVLVLVRSNE MLBr_02143|M.leprae_Br4923 LRQSWPEEVKKVSGRLRQPLGRNIITSLWGNCTIKVMVGFLFLYPAFVAK TH_1066|M.thermoresistible__bu LRR--HPDQRRHSGAARQPMGRNTITALWGNCTIKLMVGFLFLYPAFVAK : .* .: : ::.* . Mflv_0849|M.gilvum_PYR-GCK TATVAG---FGTTVLFVIAGGAGQFVATIATPALVTRWGRYAAPNGALAL Mvan_6058|M.vanbaalenii_PYR-1 AATVAG---FGTTVLFVSAGGAGQFLATVVTPTLVKKWGRYATPNGALAF MSMEG_6922|M.smegmatis_MC2_155 TPTQVAGVGLGTAVVFVGATGAGTFLATLVMPAVVARFGRYATANGALAF Mb0038c|M.bovis_AF2122/97 ARAVGG---LGTALLFFAATGLGAFLANVLTPTAIRRWGRYATANGALAA Rv0037c|M.tuberculosis_H37Rv ARAVGG---LGTALLFFAATGLGAFLANVLTPTAIRRWGRYATANGALAA MMAR_0052|M.marinum_M DVDVEG---LGTALLFFAATGLGAFLANVLTPGLIRRWGRYATTNGALAA MUL_0051|M.ulcerans_Agy99 DVDVEG---LGTALLFFAATGLGAFLANVLTPGLIRRWGRYATTNGALAA MAV_0051|M.avium_104 GLEGGG---FGTALLFFGAAGLGAFLANVLTPPAIRRWGRYATANGALAA MAB_4929|M.abscessus_ATCC_1997 S-VFAG---IGAAALFLACTGIGSFLGTVSTPALLRRFGRGRTLGMALGG MLBr_02143|M.leprae_Br4923 EHQANGWVQLGMLGLIGTAAAIGNFAGNFTSARLQLGRPAVLVVRCTIAV TH_1066|M.thermoresistible__bu SHEATGLEQLMILGLIGAAAAVGNFIGNFTAARLELGHPAQLVVRAAIAV . : :: . . * * ... . . ::. Mflv_0849|M.gilvum_PYR-GCK AAVVQVCAATLQLPVMIVCGFVLGAAGQVVKLCADSAMQIDVDDALRGHM Mvan_6058|M.vanbaalenii_PYR-1 AAAVQLCGATLNLPVMIVCGFLLGAAGQVVKLCADTAMQIDVEDALRGHL MSMEG_6922|M.smegmatis_MC2_155 AALVQAVALSLHLPVMLVCGFLLGAAGQFVKLCADSAMQIDVDDALRGHV Mb0038c|M.bovis_AF2122/97 AATIQVAAAGLLVPVMVVCGFLLGVAGQVVKLCADSAMQMDVDDALRGHV Rv0037c|M.tuberculosis_H37Rv AATIQVAAAGLLVPVMVVCGFLLGVAGQVVKLCADSAMQMDVDDALRGHV MMAR_0052|M.marinum_M AAVIQLAGAGLLLPVMVVCGFLLGVAGQVVKLCADSAMQIDVDDALRGHV MUL_0051|M.ulcerans_Agy99 AAVTQLAGAGLLLPVMVVCGFLLGVAGQVVKLCADSAMQIDVDGALRGHV MAV_0051|M.avium_104 SAIIEVAGAELLLPVMVVCGFLLGVTGQMVKLCADSAMQMDVDDALRGHV MAB_4929|M.abscessus_ATCC_1997 AVVLQLIASGLYIPILLASAFGLGMAGQVIKLCADVGMQTDVDDALRGHV MLBr_02143|M.leprae_Br4923 TVLALAASVAGNLLMTTIATLITSGSSAIAKASLDASLQNDLPEESRASG TH_1066|M.thermoresistible__bu TIGALATAVTGELLVAALATLITSGASAIAKASLDASLQDDLPEQSRASA : . : : . : . :. . * . * .:* *: *. Mflv_0849|M.gilvum_PYR-GCK FAVQDSLFWVAFIVAITGAAAVIPADGHSPALAVAGTGLYLAGLAAHAV- Mvan_6058|M.vanbaalenii_PYR-1 FAVQDALFWLAFIVAISAAAFVIPPDGRSVGLAVAGVGTYLAGLAVHAT- MSMEG_6922|M.smegmatis_MC2_155 FTVQDALFWMSFVCAIAVAALVIAPDGHSPGLVAAGSVIYLAGLGLHAF- Mb0038c|M.bovis_AF2122/97 FAVQDALFWVSYILSITVAAALIPEHGHAPVFVLFGSAIYLAGLVVHTI- Rv0037c|M.tuberculosis_H37Rv FAVQDALFWVSYILSITVAAALIPEHGHAPVFVLFGSAIYLAGLVVHTI- MMAR_0052|M.marinum_M FAVQDALFWVSYIVSVTVAAALIPDDGRAPVFVLVGSVIYLIGLCVHSI- MUL_0051|M.ulcerans_Agy99 FAVQDALFWVSYIVSVTVAAALIPDDGRAPVFVLVGSLIYLLGLCVHSI- MAV_0051|M.avium_104 FAVQDALFWVAFIVAITVAGMVIPDDGHAPVFALFGSVLYLVGLAVHGI- MAB_4929|M.abscessus_ATCC_1997 FAVQDSLFWVTFTGAMAVGAAFIT---HAHWLAFSGAMIYLAGLIVHMTR MLBr_02143|M.leprae_Br4923 FGRSESTLQLAWVLGGALGVMVYTDLWVGFTAVSALLILGLAQTVVSFRG TH_1066|M.thermoresistible__bu FGRSESLLQLAWVAGGATGVLVYTELWIGFTTISAILILGLAQTIVSYRG * .:: : ::: . : . . . . * Mflv_0849|M.gilvum_PYR-GCK -----------------MGRRGR-RG------------- Mvan_6058|M.vanbaalenii_PYR-1 -----------------VGRRGRPRG------------- MSMEG_6922|M.smegmatis_MC2_155 -----------------VASPRRA--------------- Mb0038c|M.bovis_AF2122/97 -----------------VGRR--GQPVIGR--------- Rv0037c|M.tuberculosis_H37Rv -----------------VGRR--GQPVIGR--------- MMAR_0052|M.marinum_M -----------------VGRRSSAANVEGG--------- MUL_0051|M.ulcerans_Agy99 -----------------VGRRSSASNVEGC--------- MAV_0051|M.avium_104 -----------------VGRR--GE-------------- MAB_4929|M.abscessus_ATCC_1997 TLWPSTLDTGSLPTQPNAGSLPTQPNPEGQARDLDR--- MLBr_02143|M.leprae_Br4923 DSLIPG----------LGGNRPVMIEQESMRRAAAVSPQ TH_1066|M.thermoresistible__bu DSLIPG----------FGGNRPVLAEPEGRNDHPAFTPR .