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MPAPDAVSLTATNIHLAFGPNKVLRGVDLDVPAGTTTAVIGPSGSGKSTLLRTLNRLYEPDEGDVLLDGR SVLRDNPDQLRQRIGMVFQQFNLFPHRSVLDNVTLGPRRLKGLGADDARELGLAQLDRVGLRHKADVRPG TLSGGQQQRVAIARALAMAPQVMFFDEATSALDPELVKGILSLMADLAADGMTIVAVTHEMGFARSTANT VVFMDQGRVVESGEPDQLFEAAETDRLRRFLSQVL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6911 | - | - | 100% (245) | ABC transporter, ATP-binding protein GluA |
| M. smegmatis MC2 155 | MSMEG_2728 | - | 1e-64 | 51.04% (241) | glutamate transport ATP-binding protein GluA |
| M. smegmatis MC2 155 | MSMEG_6593 | - | 1e-63 | 52.21% (249) | ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3784c | proV | 5e-35 | 42.47% (219) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. gilvum PYR-GCK | Mflv_0857 | - | 1e-111 | 83.33% (240) | ABC transporter related |
| M. tuberculosis H37Rv | Rv0933 | pstB | 2e-37 | 38.06% (247) | phosphate ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_01892 | - | 2e-30 | 30.45% (243) | ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_3050 | - | 7e-61 | 46.12% (245) | putative glutamate ABC transporter, ATP-binding protein |
| M. marinum M | MMAR_0060 | - | 1e-103 | 77.82% (239) | glutamine ABC transporter, ATP-binding protein |
| M. avium 104 | MAV_0058 | - | 1e-104 | 77.50% (240) | ABC transporter, ATP-binding protein |
| M. thermoresistible (build 8) | TH_0514 | - | 1e-115 | 84.90% (245) | ABC transporter, ATP-binding protein GluA |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 8e-35 | 39.04% (228) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_6048 | - | 1e-111 | 83.33% (240) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3784c|M.bovis_AF2122/97 --------------------MICFDDVSKVYAHGATAVDRLTLEVPNGML
MUL_3658|M.ulcerans_Agy99 -----------MTGPGTGGHAIVVRDAFKQYGD-FVALDHVDFVVPAGSL
MSMEG_6911|M.smegmatis_MC2_155 -------------MPAPDAVSLTATNIHLAFGP-NKVLRGVDLDVPAGTT
TH_0514|M.thermoresistible__bu -------------MTQPKAVSLAATDIHLAFGP-NKVLRGVDLEVPAGTT
Mflv_0857|M.gilvum_PYR-GCK -------------MTS--AVSLAATDIHLSFGT-TAVLRGVDLDVAAGSS
Mvan_6048|M.vanbaalenii_PYR-1 -------------MTT--AVSLTAKDIHLSFGK-SAVLRGVDLDVAAGSS
MMAR_0060|M.marinum_M ---------MTRQDAGRQPVCLAARSIHQTLGG-SVVLRGVDLEVPAGTT
MAV_0058|M.avium_104 ---------MS-NPASRASVSLACKDIHQTLNG-NAVLRGVDLDTPAGST
MAB_3050|M.abscessus_ATCC_1997 MPVSTDTSTSGESSSAPSVPMIALEHVNKHFGD-LHVLKDITLEIPRGQV
Rv0933|M.tuberculosis_H37Rv MACERLGGQSGAADVDAAAPAMAAVNLTLGFAG-KTVLDQVSMGFPARAV
MLBr_01892|M.leprae_Br4923 ---------------MPMGVAIEVKGLTKSFGS-SRIWEDVTLDIPAGEV
: : : .
Mb3784c|M.bovis_AF2122/97 TVFVGPSGCGKTTALRMINRMVDPTS-----GTITVDGTDVSTVNA---V
MUL_3658|M.ulcerans_Agy99 TALLGPSGSGKSTLLRTIAGLDQPDS-----GNITINGRDVTRVPP---Q
MSMEG_6911|M.smegmatis_MC2_155 TAVIGPSGSGKSTLLRTLNRLYEPDE-----GDVLLDGRSVLRDNP---D
TH_0514|M.thermoresistible__bu AAVIGPSGSGKSTLLRTLNRLYEPDR-----GDILLDGRSVLRDNP---D
Mflv_0857|M.gilvum_PYR-GCK TAVIGPSGSGKSTLLRTLNRLYEPDR-----GDILLDGRSVLRDDP---N
Mvan_6048|M.vanbaalenii_PYR-1 TAVIGPSGSGKSTLLRTLNRLYEPDR-----GDILLDGRSVLGDNP---D
MMAR_0060|M.marinum_M AAVIGPSGSGKSTLLRTLNRLHEPDS-----GDILLDGRSVLRDNP---N
MAV_0058|M.avium_104 VAVIGPSGSGKSTLLRTLNRLYEPDR-----GDILLDGRSVLHDDP---D
MAB_3050|M.abscessus_ATCC_1997 VVILGPSGSGKSTLCRTINRLEPIDG-----GTIRIDG-AILPEEGRALA
Rv0933|M.tuberculosis_H37Rv TSLMGPTGSGKTTFLRTLNRMNDKVSGYRYSGDVLLGGRSIFNYRD--VL
MLBr_01892|M.leprae_Br4923 SVLLGPSGTGKSVFLKSLIGLLRPER-----GSILIDGTDIIECSAKELY
.:**:* **:. : : : * : :.* :
Mb3784c|M.bovis_AF2122/97 KLRLGIGYVIQNAGLMPHQRVIDNVATVP-VLKGQPRRAARKAGYEVLER
MUL_3658|M.ulcerans_Agy99 RR--GIGFVFQHYAAFKHLTVRDNVAYGL-KIRKRPKAEIRDKVDNLLEV
MSMEG_6911|M.smegmatis_MC2_155 QLRQRIGMVFQQFNLFPHRSVLDNVTLGPRRLKGLGADDARELGLAQLDR
TH_0514|M.thermoresistible__bu QLRQRIGMVFQHFNLFPHRTVLDNVTLAPRKLKRLSRDEARELGLRQLER
Mflv_0857|M.gilvum_PYR-GCK ALRQRIGMVFQQFQLFPHKSVLDNVTLGPRKLKKMSADAARELGMAQLDR
Mvan_6048|M.vanbaalenii_PYR-1 QLRQRIGMVFQHFQLFPHRTVLDNVTLAPRKLKRLSGDEARELGMAQLDR
MMAR_0060|M.marinum_M DLRQRIGMVFQHFNLFPHRNVVDNVTLAPRKLRGLSNEEARMLALDQLDR
MAV_0058|M.avium_104 QLRQRIGMVFQHFNLFPHRTVLDNVALAPRKLRRLPAEAARELALTQLDR
MAB_3050|M.abscessus_ATCC_1997 SLRAEVGMVFQSFNLFSHKTILDNVTLAPIKVRKHNKETARKRAIELLER
Rv0933|M.tuberculosis_H37Rv EFRRRVGMLFQRPNPFP-MSIMDNVLAGVRAHKLVPRKEFRGVAQARLTE
MLBr_01892|M.leprae_Br4923 EIRTLFGVLFQDGALFGSMNLYDNTAFPLREHTKKKESEIRDIVMEKLQL
.* ::* : : **. * *
Mb3784c|M.bovis_AF2122/97 VGLDPKVATRY---PAQLSGGEQQRVGVARALAADPPILLMDEPFSAVDP
MUL_3658|M.ulcerans_Agy99 VGLS-GFHGRY---PDQLSGGQRQRMALARALAVDPEVLLLDEPFGALDA
MSMEG_6911|M.smegmatis_MC2_155 VGLR-HKADVR---PGTLSGGQQQRVAIARALAMAPQVMFFDEATSALDP
TH_0514|M.thermoresistible__bu VGLR-HKAEVR---PTTLSGGQQQRVAIARALAMDPQVMFFDEATSALDP
Mflv_0857|M.gilvum_PYR-GCK VGLR-NKADVR---PSTLSGGQQQRVAIARALAMSPQVMFFDEATSALDP
Mvan_6048|M.vanbaalenii_PYR-1 VGLR-NKADAR---PATLSGGQQQRVAIARALAMSPQVMFFDEATSALDP
MMAR_0060|M.marinum_M VGLK-HKANAR---PDMLSGGQQQRVAIARALAMAPQVMFFDEATSALDP
MAV_0058|M.avium_104 VGLK-HKAGAR---PATLSGGQQQRVAIARALAMSPQVMFFDEATSALDP
MAB_3050|M.abscessus_ATCC_1997 VGIA-SQKDKY---PAQLSGGQQQRVAIARSLAMGPKVMLFDEPTSALDP
Rv0933|M.tuberculosis_H37Rv VGLWDAVKDRLSDSPFRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDP
MLBr_01892|M.leprae_Br4923 VGLG-GDEKKF---PGEISGGMRKRAGLARALVLDPQIILCDEPDSGLDP
**: * :*** :: :**:*. * ::: **. ..:*.
Mb3784c|M.bovis_AF2122/97 VVRHELQNEILRLQAELHKTIVFVTHDIDEALKLADLVAVFAPGGALAQY
MUL_3658|M.ulcerans_Agy99 KVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNSG-RIEQV
MSMEG_6911|M.smegmatis_MC2_155 ELVKGILSLMADLAADG-MTIVAVTHEMGFARSTANTVVFMDQG-RVVES
TH_0514|M.thermoresistible__bu ELVKGILALIADLAESG-MTMVVVTHEMGFARSTADTVVFMDHG-QVVES
Mflv_0857|M.gilvum_PYR-GCK ELVKGVLALIAELASDG-MTMVVVTHEMGFARSTADQLVFMDHG-QVVET
Mvan_6048|M.vanbaalenii_PYR-1 ELVKGVLELIADLGAEG-MTMVVVTHEMGFARSSADTVVFMDHG-QVVET
MMAR_0060|M.marinum_M EMVKGILALIADLGADG-MTMVVVTHEMGFARSTSDAVVFMDHG-TVVEA
MAV_0058|M.avium_104 EMVKGILQLIADLGAEG-MTMVVVTHEMGFARSASDAVIFMDHG-KVVES
MAB_3050|M.abscessus_ATCC_1997 EMVNEVLDVMVSLAKEG-MTMLVVTHEMGFARKAADRIIFMADG-AIVED
Rv0933|M.tuberculosis_H37Rv TTTEKIEEFIRSLADRL--TVIIVTHNLAQAARISDRAALFFDG-RLVEE
MLBr_01892|M.leprae_Br4923 VRTAYLSQLIMDINAQIDATILIVTHNVNIARTVPDNMGMLFRK-HLVMF
: : : * : ***: * .: .: :
Mb3784c|M.bovis_AF2122/97 DETARLLSSPANDFVSKFIGLGRGYRWLQLFDAAGLPVRDIEQVSVNGLS
MUL_3658|M.ulcerans_Agy99 GSPTEVYDAPTNAFVMSFLGAVSALNG-ALVRPHDIRVGRTPEMAVAAAD
MSMEG_6911|M.smegmatis_MC2_155 GEPDQLFEAAETDRLRRFLSQVL---------------------------
TH_0514|M.thermoresistible__bu GPPQQIFESAATERLRRFLSQVL---------------------------
Mflv_0857|M.gilvum_PYR-GCK GPPEQLFEAAETDRLRRFLSQVL---------------------------
Mvan_6048|M.vanbaalenii_PYR-1 GPPEQLFEAAETDRLRRFLSQVL---------------------------
MMAR_0060|M.marinum_M GPPEQLFEAARTERLQRFLAQVL---------------------------
MAV_0058|M.avium_104 GPPEQIFEAAETERLQRFLSQVL---------------------------
MAB_3050|M.abscessus_ATCC_1997 SDPESFFTNPKSERAKDFLGKILGH-------------------------
Rv0933|M.tuberculosis_H37Rv GPTEQLFSSPKHAETARYVAGLSGDVKDAKRGN-----------------
MLBr_01892|M.leprae_Br4923 GPREVLLTSDEPVVRQFLNGRRIGPIGMSEEKDESTMAEEAALLEAGHYA
. . .
Mb3784c|M.bovis_AF2122/97 DARDRQVRDGWVLVVDGAGAPLGWIDADGRRRHRGGAALSDAMTVGGSVF
MUL_3658|M.ulcerans_Agy99 GTGES---TGVTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAEA
MSMEG_6911|M.smegmatis_MC2_155 --------------------------------------------------
TH_0514|M.thermoresistible__bu --------------------------------------------------
Mflv_0857|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_6048|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
MAB_3050|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0933|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01892|M.leprae_Br4923 GGAEEVEGVPPQITVTPG---MPKRKAVARRQARVRAMLPTLPKGAQAAI
Mb3784c|M.bovis_AF2122/97 RPNGNLSQALDAALSSPSGVGVAVDGGGKVIGGILAADVLAEFQKGKKAG
MUL_3658|M.ulcerans_Agy99 LALQEGDTVYVRATRVPPIAGAAP---------AVPDDGAGSTPRAAQIG
MSMEG_6911|M.smegmatis_MC2_155 --------------------------------------------------
TH_0514|M.thermoresistible__bu --------------------------------------------------
Mflv_0857|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_6048|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
MAB_3050|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0933|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01892|M.leprae_Br4923 LDDLEGAHNYQAHEFGD---------------------------------
Mb3784c|M.bovis_AF2122/97 GGAKPCTT
MUL_3658|M.ulcerans_Agy99 VGGQ----
MSMEG_6911|M.smegmatis_MC2_155 --------
TH_0514|M.thermoresistible__bu --------
Mflv_0857|M.gilvum_PYR-GCK --------
Mvan_6048|M.vanbaalenii_PYR-1 --------
MMAR_0060|M.marinum_M --------
MAV_0058|M.avium_104 --------
MAB_3050|M.abscessus_ATCC_1997 --------
Rv0933|M.tuberculosis_H37Rv --------
MLBr_01892|M.leprae_Br4923 --------