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MGEPFIGSEALAAGTLTRHQLRSRFIAVYQDIYVEKGTLPTAILRAKACWLRSRRRGVLAGYSAAALHGA RWIDPGLPAYILDTNRRPARGVVVWSDAIEDDEICLIGDMRVTTPVRTALDLACKFPEDVAVPAIDSLAR AAKLKVADIELAAEHHAARRGIRQARTIIALVDPGAESPRETWLRLVVVRAGYPPPQTQYAVLNEYGALI GEVDMAWPELKIALEYEGQHHTDPVTLRKDIQRADEMMENGWIVIRVTARDGEATVLKRVAKAWASRS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5643 | - | - | 100% (278) | hypothetical protein MSMEG_5643 |
| M. smegmatis MC2 155 | MSMEG_5917 | - | 4e-85 | 55.04% (278) | hypothetical protein MSMEG_5917 |
| M. smegmatis MC2 155 | MSMEG_0785 | - | 5e-66 | 46.40% (278) | hypothetical protein MSMEG_0785 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1518c | - | 6e-88 | 57.14% (280) | hypothetical protein Mb1518c |
| M. gilvum PYR-GCK | Mflv_4708 | - | 2e-83 | 55.40% (278) | hypothetical protein Mflv_4708 |
| M. tuberculosis H37Rv | Rv1482c | - | 6e-88 | 57.14% (280) | hypothetical protein Rv1482c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1570 | - | 4e-72 | 47.48% (278) | hypothetical protein MAB_1570 |
| M. marinum M | MMAR_5026 | - | 2e-66 | 46.59% (279) | hypothetical protein MMAR_5026 |
| M. avium 104 | MAV_0642 | - | 2e-84 | 56.27% (279) | hypothetical protein MAV_0642 |
| M. thermoresistible (build 8) | TH_1775 | - | 6e-95 | 58.76% (274) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2811 | - | 4e-60 | 44.00% (275) | hypothetical protein MUL_2811 |
| M. vanbaalenii PYR-1 | Mvan_5044 | - | 6e-54 | 41.54% (272) | hypothetical protein Mvan_5044 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1518c|M.bovis_AF2122/97 ----MTDPFLGSEALAAGVLTPYELRSRYVALHKDVYVPQGVELTAQLRA
Rv1482c|M.tuberculosis_H37Rv ----MTDPFLGSEALAAGVLTPYELRSRYVALHKDVYVPQGVELTAQLRA
MSMEG_5643|M.smegmatis_MC2_155 ----MGEPFIGSEALAAGTLTRHQLRSRFIAVYQDIYVEKGTLPTAILRA
TH_1775|M.thermoresistible__bu MAAPFSEPFLGSEALTSGALTRHQLRTRYRAIHRDVYIANDAELDAVLRA
Mflv_4708|M.gilvum_PYR-GCK ----MGEPFIGSEALRAGRLTRHQLRTAHIAVYPDVYVPVATTLTAVAKA
MAV_0642|M.avium_104 ----MAEPFIGSEAVASGLVTPYALRSRFVRVHPDVYVPAGTALSAGLRA
MAB_1570|M.abscessus_ATCC_1997 ----MGEPFVGSEAVRSGRLTAYALRTRYVAIHPDVYLPRGAQLTPLVRA
MMAR_5026|M.marinum_M ----MAVPFLGSEAVASGEVRKSALRTRYHRLFPDVYIRCDAELSPQARA
MUL_2811|M.ulcerans_Agy99 -MCDLRAPFIGSKALACGAVTRHQLRTRYRPVLPNVYLSAGVHPCLQSRI
Mvan_5044|M.vanbaalenii_PYR-1 -----MDPFLGTEALAAGSLTRYRLKTRFELVHRNVYALNREQLTPVQKA
**:*::*: .* : *:: . : ::* :
Mb1518c|M.bovis_AF2122/97 KALWLRSRRRGVLAGYSASAFHGAKWIDADLPAAIIDTNRRRAPGLQVWE
Rv1482c|M.tuberculosis_H37Rv KALWLRSRRRGVLAGYSASAFHGAKWIDADLPAAIIDTNRRRAPGLQVWE
MSMEG_5643|M.smegmatis_MC2_155 KACWLRSRRRGVLAGYSAAALHGARWIDPGLPAYILDTNRRPARGVVVWS
TH_1775|M.thermoresistible__bu KACWLRSRGHGVLAGFSASALHGAKYVDPRRPATVIDTNRRRTPGILTWG
Mflv_4708|M.gilvum_PYR-GCK KAASLWTGREGIIAGQSAAAIHGARWVDARRPAEVLWHNRRAPRGVLVWS
MAV_0642|M.avium_104 RSAWLWSRRRGVVAGRSAAALYGTKWIDDRAPAQLLYPYRRPPDGIQTWS
MAB_1570|M.abscessus_ATCC_1997 QASWLWTGRRGILAGHSASALHGARWIDAARNAEIVHDNRHRQPGITVWS
MMAR_5026|M.marinum_M RAGWLWSRRRGIVAGLAASALHGARWVDPDAPLDILHVNRNPRPGIRARG
MUL_2811|M.ulcerans_Agy99 AAAWLWSRGSATVGGAAAAALHGAKWIPEDVPVELICARSSPPRGVLTRR
Mvan_5044|M.vanbaalenii_PYR-1 RAAWLWSGRRGTLVGLSAAAVLGSRWIDARLPAELNQRSQHKTPGIVLRA
: * : . : * :*:*. *:::: : *:
Mb1518c|M.bovis_AF2122/97 ERIEPDEICVIEGMRVTTPERTALDLTSRFPLDPAVAAVDALIQATDLKV
Rv1482c|M.tuberculosis_H37Rv ERIEPDEICVIEGMRVTTPERTALDLTSRFPLDPAVAAVDALIQATDLKV
MSMEG_5643|M.smegmatis_MC2_155 DAIEDDEICLIGDMRVTTPVRTALDLACKFPEDVAVPAIDSLARAAKLKV
TH_1775|M.thermoresistible__bu HTLDEDEICEIDGMRLTTPARTAVDLACRYPVGTSVAAIDALARAARLKV
Mflv_4708|M.gilvum_PYR-GCK DRVADDEVTTVRGVRVTTPERTALDIACRYPQRRAVAAIDALARAAHMKL
MAV_0642|M.avium_104 DRLVGDEIQTIGGMPVTTPARTALDIACRSPVDKAVAAIDALARATELKV
MAB_1570|M.abscessus_ATCC_1997 GEIAPDEICVVRGMRATTAARTALDLACRCPRGRAVAAIDALCRATELQI
MMAR_5026|M.marinum_M DRIATDEVMQIGGIPVTTPARTALDLGCWYPTGEAVAAIDSLMRAADVGR
MUL_2811|M.ulcerans_Agy99 DVLIDGETQFLGGYSVTTAERTAFDIGRRGAMRSAVVRLDALARATGFTV
Mvan_5044|M.vanbaalenii_PYR-1 DTLGPDEIVTARGMPVTSPARTAFDLGRRRGLTLAVIRMDALMRTTGATT
: .* . *:. ***.*: :* :*:* :::
Mb1518c|M.bovis_AF2122/97 ADVEPLIERYRGRRGMKAARAALDLVDGGAQSPKETWLRLLLIRAGFPRP
Rv1482c|M.tuberculosis_H37Rv ADVEPLIERYRGRRGMKAARAALDLVDGGAQSPKETWLRLLLIRAGFPRP
MSMEG_5643|M.smegmatis_MC2_155 ADIELAAEHHAARRGIRQARTIIALVDPGAESPRETWLRLVVVRAGYPPP
TH_1775|M.thermoresistible__bu ADIEAAAQRHPGRHGLRRAREAIALVDPGAESPRETALRLLIVRAGYPPP
Mflv_4708|M.gilvum_PYR-GCK ADVELLVDRHTGRRGIRAARAALNLVDPGAESPQETYLRLTVIGNHFPPP
MAV_0642|M.avium_104 LEIELLADRYRGRRGITRARNVLPLVDAGAESPRETWLRLLLLRAGFPRP
MAB_1570|M.abscessus_ATCC_1997 SEALELASRHAGMRGIRRARTAFELVDAGAQSPKETWLRLLLRDAGLPPV
MMAR_5026|M.marinum_M AQIETLLHRYPTRRWIRRARRAVERADPGAQSPKETWLRLLLLDDGLPRP
MUL_2811|M.ulcerans_Agy99 ADVLQVARNHRGTRGLRQLETALELVDPGAQSPRESYLRLFLIDAGLPRP
Mvan_5044|M.vanbaalenii_PYR-1 SDIATLLTRHKGARGLVQLRRALELVDPASESPQESRTRLLLVKAGLPPE
: .: : : . . .* .::**:*: ** : *
Mb1518c|M.bovis_AF2122/97 QTQIAVRNEWGWAEAHLDMGWQDIKVAAEYDGDHHLTSRYHYRKDILRHE
Rv1482c|M.tuberculosis_H37Rv QTQIAVRNEWGWAEAHLDMGWQDIKVAAEYDGDHHLTSRYHYRKDILRHE
MSMEG_5643|M.smegmatis_MC2_155 QTQYAVLNEYGALIGEVDMAWPELKIALEYEGQHH-TDPVTLRKDIQRAD
TH_1775|M.thermoresistible__bu ETQLPIHNEFGVLIGVVDMGWRDRRIAVEYEGRHHFTSRRAINRDIRRHD
Mflv_4708|M.gilvum_PYR-GCK QTQIPVW-DCGALVAELDMGWEHMMIGLDYEGDHHRTTREAFNKGIRRHD
MAV_0642|M.avium_104 RTQLPVR-QYGALIACLDMGWEDIKLAVEYDGDQHRTDRRQFTKDIRRAE
MAB_1570|M.abscessus_ATCC_1997 STQILVHNGDFVALAYIDMGWEDVMVGIEYDGDQHRSDRRQYLKDIRRLE
MMAR_5026|M.marinum_M QTQIRVADEWGELVAYLDMGWEELMVAVEYDGEQHRNDRRQYSWDIRRKE
MUL_2811|M.ulcerans_Agy99 QTQLPVLGVNGMPVAYLDMGWERYMVAVEYDGDHHRSDRQQYVKDIRRGE
Mvan_5044|M.vanbaalenii_PYR-1 RSQIDVFDRDGYHVGRVDMGWETWKVGVEYEGEQHWTNPEQYAHDIDRQA
:* : . :**.* :. :*:* :* . .* *
Mb1518c|M.bovis_AF2122/97 KVQHRYGWIVVRVVAE---DHPADIIRRVGEARAFRA-------------
Rv1482c|M.tuberculosis_H37Rv KVQHRYGWIVVRVVAE---DHPADIIRRVGEARAFRA-------------
MSMEG_5643|M.smegmatis_MC2_155 EMME-NGWIVIRVTAR---DGEATVLKRVAKAWAS---------------
TH_1775|M.thermoresistible__bu DMLE-MGWTVLRVTAA---DTDGGFLRRLETAWSRPAEHS---PAQHSPA
Mflv_4708|M.gilvum_PYR-GCK AVTE-LGWTDIRVTCN---DTEGAIIARLTTAWRQRLCALGENPDAGPPW
MAV_0642|M.avium_104 VLAE-LGWTVVRVTAE---DTPAGIIARVPTAWTRRACTG----------
MAB_1570|M.abscessus_ATCC_1997 MLEG-MGWLIVRVVAE---DHPHDIIRRVREALARRV-------------
MMAR_5026|M.marinum_M ILER-LGWTVIRVLAG---DRPTDILRRVRAALVRRASR-----------
MUL_2811|M.ulcerans_Agy99 MLER-MGWIVIRVVAE---DRRVDILRRVTAALAERRSAVP---------
Mvan_5044|M.vanbaalenii_PYR-1 ALEA-EGWRIIRVSAEILRDRPTTIVSRVWLALRAAGAPVQPPNLNL---
: ** :** . * .: *: *
Mb1518c|M.bovis_AF2122/97 ----------
Rv1482c|M.tuberculosis_H37Rv ----------
MSMEG_5643|M.smegmatis_MC2_155 -RS-------
TH_1775|M.thermoresistible__bu QRSPAQRS--
Mflv_4708|M.gilvum_PYR-GCK THVRRQRPGQ
MAV_0642|M.avium_104 SEKPARNSR-
MAB_1570|M.abscessus_ATCC_1997 ----------
MMAR_5026|M.marinum_M ----------
MUL_2811|M.ulcerans_Agy99 ----------
Mvan_5044|M.vanbaalenii_PYR-1 ----------