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HRVVVLVRDGMIPLEVGIPHRLFGQARSTSGERLYDVVTATLTPGPVRTDTDFTINVANGPDVLAQADTV VIPASDEDYAPPTQGRLSPELATALSHIKPGTRMASICTGSFVLAAAGLLDERRATTHWRSAGDFRRLFP HIELDPNVLFTDCDDVLTSAGVAAGLDLCLHMIRSDFGAAVANEVARGTVTPPHREGGQAQYIQRLVPEP TTAATGAARAWAAERLDEAITLDDMAAVSAMSKRTFTRRFRAETGLSPMQWLTEQRLHRACELLEQTDFP VERVAAESGLGSGTAMRQLFQSAMGVTPSAYRATFRGRELSSGDG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5563 | - | - | 100% (326) | AraC-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5193 | - | 1e-81 | 50.47% (321) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_6839 | - | 6e-64 | 42.20% (327) | transcriptional regulator, AraC family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1966c | - | 1e-11 | 27.86% (262) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_1693 | - | 5e-69 | 45.06% (324) | AraC family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1931c | - | 1e-11 | 27.86% (262) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2445 | - | 4e-66 | 44.44% (315) | AraC family transcriptional regulator |
| M. marinum M | MMAR_2855 | - | 2e-39 | 33.86% (316) | transcriptional regulatory protein |
| M. avium 104 | MAV_4981 | - | 2e-41 | 34.07% (317) | transcriptional regulator, AraC family protein |
| M. thermoresistible (build 8) | TH_3120 | - | 2e-60 | 40.25% (323) | PUTATIVE transcriptional regulator, AraC family with |
| M. ulcerans Agy99 | MUL_2902 | - | 1e-37 | 33.23% (316) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5349 | - | 4e-60 | 40.32% (315) | AraC family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5563|M.smegmatis_MC2_155 -------MHRVVVLVRDGMIPLEVGIPHRLFGQAR-----STSGERLYDV
Mflv_1693|M.gilvum_PYR-GCK -------MHTVAILAYDGMSGFESGLAAEIFGMTELSERFSAGLTRPWYT
TH_3120|M.thermoresistible__bu ----------VAALVLDGLAIFEFGVICEVFGVDRT----DDGVPP-VDF
Mvan_5349|M.vanbaalenii_PYR-1 -----MAIRSVSALVLDNLAMFEFGVICEVFGIDRS----ADGVPN-FDF
MAB_2445|M.abscessus_ATCC_1997 -----MGTKTVAALALDGVITYDLACAVQMFRRGPG----RTGQPDGFDL
Mb1966c|M.bovis_AF2122/97 ----------MVIVGFPG--------------------------------
Rv1931c|M.tuberculosis_H37Rv ----------MVIVGFPG--------------------------------
MMAR_2855|M.marinum_M ------MARKVVIVGFPGVQPLDVVGPFEVFAGASL-------LSEGGYD
MUL_2902|M.ulcerans_Agy99 ------MARKVVTVGFPGVQPLDVVGPFEVFAGASL-------LSEGGYD
MAV_4981|M.avium_104 MADSSATPRVVVIVVFDDVTMLDVAGAGEVFAEANR-------FG-ADYL
: : .
MSMEG_5563|M.smegmatis_MC2_155 VTATLTPGP-VRTDTDFTINVANGPDVLAQADTVVIPASDEDYAPPTQGR
Mflv_1693|M.gilvum_PYR-GCK VKLCSESAE-LRLLGGATVRTAYDLSDLAEADTVVIPSVR-DIGDPVSSE
TH_3120|M.thermoresistible__bu TVCGPRAGQPVRTSFGATLTPDSGLDGLAGADLVAIPAIRQDDYLP---E
Mvan_5349|M.vanbaalenii_PYR-1 KVCGPEAGSPLRTSVGATIIPDHGLDHLVGADLVAIPAIGGSDYLP---E
MAB_2445|M.abscessus_ATCC_1997 VTCGHRPGS-VWTPDGFHLDVEHGVDTLEAADIVVVPARAPHDHPPPD-D
Mb1966c|M.bovis_AF2122/97 ----------------------------DPVDTVILPGGAGVDAARSEPA
Rv1931c|M.tuberculosis_H37Rv ----------------------------DPVDTVILPGGAGVDAARSEPA
MMAR_2855|M.marinum_M VALASIDERPVATGIGLEFMTTRLPDPSAPVDTVVLPGGGGVDAARDNVA
MUL_2902|M.ulcerans_Agy99 VALASIDERPVATGIGLEFMTTRLPDPSAPVDTVVLPGGGGVDAARDNVA
MAV_4981|M.avium_104 LKIASVDGRDVTTSIGTRLGVTDAVSSIESADTVLVAGSDNLPRRPIDPE
.* * :..
MSMEG_5563|M.smegmatis_MC2_155 LSPELATALSHIKPGTRMASICTGSFVLAAAGLLDERRATTHWRSAGDFR
Mflv_1693|M.gilvum_PYR-GCK LVDAIKTADAR---GARLVSICSGAFALAAAGVLDGHKATTHWIYTDELR
TH_3120|M.thermoresistible__bu ALDAVRAAADA---GAIILTVCSGAFLAGAAGLLDGRPCTTHWGLTEELA
Mvan_5349|M.vanbaalenii_PYR-1 ALDAVRRAAES---GSIILTVCSGAFVAGAAGLLDGRPCTTHWMHADELA
MAB_2445|M.abscessus_ATCC_1997 VLNALRGAHQR---GAVVLSICLGAFVLAAAGLLDGRPATTHWEYCDDMR
Mb1966c|M.bovis_AF2122/97 LIDWVKAVSGT---ARRVVTVCTGAFLAAEAGLLG--RTPSDDALG--LC
Rv1931c|M.tuberculosis_H37Rv LIDWVKAVSGT---ARRVVTVCTGAFLAAEAGLLG--RTPSDDALG--LC
MMAR_2855|M.marinum_M LMDWVKAAAGT---ARRVVTVCTGTFLAAEAGLLDGCRATTHWAFADRLA
MUL_2902|M.ulcerans_Agy99 LMDWVKAAAGT---ARRVVTVCTGTFLAAEAGLLDGCRATTHWAFADRLA
MAV_4981|M.avium_104 LVEAVKSVADR---TRRLASICTGSFILGQAGLLDGRRATTHWHDVRLFA
: . : ::* *:* . **:*. .:. :
MSMEG_5563|M.smegmatis_MC2_155 RLFPHIELDPNVLFTDCD-DVLTSAGVAAGLDLCLHMIRSDFGAAVANEV
Mflv_1693|M.gilvum_PYR-GCK ETYPGIDIDPNPLYVDNG-RVLTSAGCAAGLDLCLHIVRTDHGVRVANDV
TH_3120|M.thermoresistible__bu RRYPTARVDRNVLYVDDG-DLITSAGTAAGIDACLHLVRRELGSEVTNTI
Mvan_5349|M.vanbaalenii_PYR-1 RMYPTAKVDRNVLFVDDG-NLITSAGTAAGIDACLHLVRRELGSEVTNKI
MAB_2445|M.abscessus_ATCC_1997 RLYPRVELRPDALYVDDG-DILTSAGLSAGMDLCLHVVRRELGAAAASDL
Mb1966c|M.bovis_AF2122/97 RTFRPR-ISGRSGRCRPDLHAQFAEGVDRGWSHRRHRPRAGTGRRRPRHR
Rv1931c|M.tuberculosis_H37Rv RTFRPR-ISGRSGRCRPDLHAQFAEGVDRGWSHRRHRPRAGTGRRRPRHR
MMAR_2855|M.marinum_M REFPAVDVDPDPIFIRSSPKVWTAAGVTAGIDLALALVEGDHGTEIAQTV
MUL_2902|M.ulcerans_Agy99 REFPAVDVDPDPIFIRSSPKVWTAAGVTAGIDLALALVEGDHGTEIAQTV
MAV_4981|M.avium_104 RAFPEITVEPDALFVCDG-DVFTSAGISSGIDLALALVEMDYGTELVRAV
. : : . : * * . . *
MSMEG_5563|M.smegmatis_MC2_155 ARGTVTPPHREGGQAQYIQRLVPEPT-TAATGAARAWAAER-----LDEA
Mflv_1693|M.gilvum_PYR-GCK ARRLVISPHRAGGQAQYIETPVPEPTEDGRIAAGMAWALEH-----LDET
TH_3120|M.thermoresistible__bu ARHMVVPPQRDGGQRQFIDQPIPVRH-SEGFAPHLDWILSN-----LDKT
Mvan_5349|M.vanbaalenii_PYR-1 ARRMVVPPQRDGGQRQYIDQPIPVKC-SERFAPHLDWILAN-----LDKP
MAB_2445|M.abscessus_ATCC_1997 ARWNVMAPHRDGGQAQFIPPVRTALG-AGGLGPTLSWAAER-----LAEI
Mb1966c|M.bovis_AF2122/97 DCPDGCPLARPVSAPTRWADPVRGSGVDATRQTDLDPPGAGGHRGRAGGA
Rv1931c|M.tuberculosis_H37Rv DCPDGCPLARPVSAPTRWADPVRGSGVDATRQTDLDPPGAGGHRGRAGGA
MMAR_2855|M.marinum_M ARWLVLYLRRPGGQ-TQFAAPVWMP--RAKRPSIRDVQEA--IEAQPGGP
MUL_2902|M.ulcerans_Agy99 ARWLVLYLRRPCGQ-TQFAAPVWMP--RAKRPSIRDVQEA--IEAQPGGP
MAV_4981|M.avium_104 ARWLVVYLKRAGGQ-SQFSALVEAE--PPPRSPLRKVTAA--ISADPAAD
* . .
MSMEG_5563|M.smegmatis_MC2_155 ITLDDMAAVSAMSKRTFTRRFRAETGLSPMQWLTEQRLHRACELLEQTDF
Mflv_1693|M.gilvum_PYR-GCK ITLDELAARSAMSRRSYLRQFAKATGTTPIRWLIEQRIQASLALLESSDH
TH_3120|M.thermoresistible__bu HTVASLARRANMSPRTFARRFVEETGRTPMQWVTDQRVLYARRLLEETDL
Mvan_5349|M.vanbaalenii_PYR-1 HTVTTLARRAHMSGRTFARRFVEETGRTPMQWVTDQRVLFARRMLEETNL
MAB_2445|M.abscessus_ATCC_1997 DDVSALARHAHLSLRTFNRRFAEEVGTTPKRWLDVQRATRARELLENTDM
Mb1966c|M.bovis_AF2122/97 HRIGELAQRAAMSPRHFTRVFSDEVGEAPGRYVERIRTEAARRQLEETHD
Rv1931c|M.tuberculosis_H37Rv HRIGELAQRAAMSPRHFTRVFSDEVGEAPGRYVERIRTEAARRQLEETHD
MMAR_2855|M.marinum_M HSIEELAHRAAMSPRHFTRVFTGEVGEAPRQYVERVRTEAARRQLEETED
MUL_2902|M.ulcerans_Agy99 HSIEELAHRAAMSPRHFTRVFTGEVGEAPGRYVERVRTEAARRQLEETED
MAV_4981|M.avium_104 HSVKSLSARASLSTRQLTRLFQSELGTTPARYVEMVRIDAARAALDAGR-
: :: : :* * * * * :* ::: * : *:
MSMEG_5563|M.smegmatis_MC2_155 PVERVAAESGLGSGTAMRQLFQSAMGVTPSAYRATFRGRELSSGDG----
Mflv_1693|M.gilvum_PYR-GCK SIDQIAARVGFESTATFRHHFVRQMHTTPSDYRSAFTGS-----------
TH_3120|M.thermoresistible__bu DIHRIAARCGFGSTTLLRHHFRRVIGVTPSDYRRRFACGSTTSGSTESGA
Mvan_5349|M.vanbaalenii_PYR-1 DIDRIAEQSGFGTATLLRHHFRRIIGVTPSDYRRRFN--STASQDVAVIA
MAB_2445|M.abscessus_ATCC_1997 TVESIAAQCGFGSVAAMRTHLRRVTATTPSAYRRAFRR------------
Mb1966c|M.bovis_AF2122/97 TVVAIAARCGFGTAETMRRSFIRRVGISPDQYRKAFA-------------
Rv1931c|M.tuberculosis_H37Rv TVVAIAARCGFGTAETMRRSFIRRVGISPDQYRKAFA-------------
MMAR_2855|M.marinum_M TVVAIAARCGFGTAETMRRNFIRRVGISPDQYRKAFA-------------
MUL_2902|M.ulcerans_Agy99 TVVAIAARCGFGTAETMRRNFIRRVGISPDQYRKAFA-------------
MAV_4981|M.avium_104 SVAESARLAGFGSAETLRRVFVEHLGLSPKAYRDRFRTAARG--------
: * *: : :* : :*. ** *
MSMEG_5563|M.smegmatis_MC2_155 ----
Mflv_1693|M.gilvum_PYR-GCK ----
TH_3120|M.thermoresistible__bu EVTD
Mvan_5349|M.vanbaalenii_PYR-1 ----
MAB_2445|M.abscessus_ATCC_1997 ----
Mb1966c|M.bovis_AF2122/97 ----
Rv1931c|M.tuberculosis_H37Rv ----
MMAR_2855|M.marinum_M ----
MUL_2902|M.ulcerans_Agy99 ----
MAV_4981|M.avium_104 ----