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MGTKTVAALALDGVITYDLACAVQMFRRGPGRTGQPDGFDLVTCGHRPGSVWTPDGFHLDVEHGVDTLEA ADIVVVPARAPHDHPPPDDVLNALRGAHQRGAVVLSICLGAFVLAAAGLLDGRPATTHWEYCDDMRRLYP RVELRPDALYVDDGDILTSAGLSAGMDLCLHVVRRELGAAAASDLARWNVMAPHRDGGQAQFIPPVRTAL GAGGLGPTLSWAAERLAEIDDVSALARHAHLSLRTFNRRFAEEVGTTPKRWLDVQRATRARELLENTDMT VESIAAQCGFGSVAAMRTHLRRVTATTPSAYRRAFRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2445 | - | - | 100% (317) | AraC family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0557 | - | 2e-72 | 44.41% (313) | AraC family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2899c | - | 4e-65 | 45.19% (312) | AraC family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1966c | - | 6e-17 | 31.37% (271) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_1437 | - | 1e-69 | 41.46% (316) | AraC family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1931c | - | 6e-17 | 31.37% (271) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2855 | - | 2e-36 | 34.51% (284) | transcriptional regulatory protein |
| M. avium 104 | MAV_4981 | - | 5e-40 | 35.31% (320) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_5193 | - | 8e-69 | 45.48% (321) | transcriptional regulator, AraC family protein |
| M. thermoresistible (build 8) | TH_3120 | - | 1e-72 | 45.98% (311) | PUTATIVE transcriptional regulator, AraC family with |
| M. ulcerans Agy99 | MUL_2902 | - | 2e-35 | 34.51% (284) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5349 | - | 3e-70 | 42.72% (316) | AraC family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1437|M.gilvum_PYR-GCK -----MAIKAVSTLVLDGLAVFEFGVVCEVFGIDRSADGVPN-FDFKVCG
Mvan_5349|M.vanbaalenii_PYR-1 -----MAIRSVSALVLDNLAMFEFGVICEVFGIDRSADGVPN-FDFKVCG
TH_3120|M.thermoresistible__bu ----------VAALVLDGLAIFEFGVICEVFGVDRTDDGVPP-VDFTVCG
MSMEG_5193|M.smegmatis_MC2_155 -------MHRVAVLLIPPVIAFDATIAPMLFGYATDADGNPL-YEVVTCG
MAB_2445|M.abscessus_ATCC_1997 -----MGTKTVAALALDGVITYDLACAVQMFRRGPGRTGQPDGFDLVTCG
Mb1966c|M.bovis_AF2122/97 ----------MVIVGFPG--------------------------------
Rv1931c|M.tuberculosis_H37Rv ----------MVIVGFPG--------------------------------
MMAR_2855|M.marinum_M ------MARKVVIVGFPGVQPLDVVGPFEVFAGASLLSEGGY---DVALA
MUL_2902|M.ulcerans_Agy99 ------MARKVVTVGFPGVQPLDVVGPFEVFAGASLLSEGGY---DVALA
MAV_4981|M.avium_104 MADSSATPRVVVIVVFDDVTMLDVAGAGEVFAEANRFG-ADY---LLKIA
: : :
Mflv_1437|M.gilvum_PYR-GCK PEPGEPLRTSVGATITPDHGLDDLVGADLVAIP----AIASRQGTYLPEA
Mvan_5349|M.vanbaalenii_PYR-1 PEAGSPLRTSVGATIIPDHGLDHLVGADLVAIP----AIGGSD--YLPEA
TH_3120|M.thermoresistible__bu PRAGQPVRTSFGATLTPDSGLDGLAGADLVAIP----AIRQDD--YLPEA
MSMEG_5193|M.smegmatis_MC2_155 VD-GEPVHSTNGFAIVPAAGPEALASADTVVVPGTTYAAARQDG-VLEED
MAB_2445|M.abscessus_ATCC_1997 HRPGS-VWTPDGFHLDVEHGVDTLEAADIVVVP----ARAPHDHPPPDDV
Mb1966c|M.bovis_AF2122/97 ------------------------DPVDTVILPG---GAGVDAARSEPAL
Rv1931c|M.tuberculosis_H37Rv ------------------------DPVDTVILPG---GAGVDAARSEPAL
MMAR_2855|M.marinum_M SIDERPVATGIGLEFMTTRLPDPSAPVDTVVLPG---GGGVDAARDNVAL
MUL_2902|M.ulcerans_Agy99 SIDERPVATGIGLEFMTTRLPDPSAPVDTVVLPG---GGGVDAARDNVAL
MAV_4981|M.avium_104 SVDGRDVTTSIGTRLGVTDAVSSIESADTVLVAG---SDNLPRRPIDPEL
.* * :. .
Mflv_1437|M.gilvum_PYR-GCK LDAIRRAAESGSIILTVCSGAFVAGAAGLLDGRPCTTHWMHADALAEMYP
Mvan_5349|M.vanbaalenii_PYR-1 LDAVRRAAESGSIILTVCSGAFVAGAAGLLDGRPCTTHWMHADELARMYP
TH_3120|M.thermoresistible__bu LDAVRAAADAGAIILTVCSGAFLAGAAGLLDGRPCTTHWGLTEELARRYP
MSMEG_5193|M.smegmatis_MC2_155 VSAALARIPAGTRLVSICTGAFVLAAAGLLDGRPATTHWRWADELRRLHP
MAB_2445|M.abscessus_ATCC_1997 LNALRGAHQRGAVVLSICLGAFVLAAAGLLDGRPATTHWEYCDDMRRLYP
Mb1966c|M.bovis_AF2122/97 IDWVKAVSGTARRVVTVCTGAFLAAEAGLLG--RTPSDDALG--LCRTFR
Rv1931c|M.tuberculosis_H37Rv IDWVKAVSGTARRVVTVCTGAFLAAEAGLLG--RTPSDDALG--LCRTFR
MMAR_2855|M.marinum_M MDWVKAAAGTARRVVTVCTGTFLAAEAGLLDGCRATTHWAFADRLAREFP
MUL_2902|M.ulcerans_Agy99 MDWVKAAAGTARRVVTVCTGTFLAAEAGLLDGCRATTHWAFADRLAREFP
MAV_4981|M.avium_104 VEAVKSVADRTRRLASICTGSFILGQAGLLDGRRATTHWHDVRLFARAFP
:. : ::* *:*: . ****. .:. : . .
Mflv_1437|M.gilvum_PYR-GCK TAKVDRNVLFVDDG-NLITSAGTAAGIDACLHLVRREMGSEVTNKIARRM
Mvan_5349|M.vanbaalenii_PYR-1 TAKVDRNVLFVDDG-NLITSAGTAAGIDACLHLVRRELGSEVTNKIARRM
TH_3120|M.thermoresistible__bu TARVDRNVLYVDDG-DLITSAGTAAGIDACLHLVRRELGSEVTNTIARHM
MSMEG_5193|M.smegmatis_MC2_155 KIAVDENVLFVDDG-DLLTSAGLAAGIDLCLHIIRTDHGAGVANAVARYC
MAB_2445|M.abscessus_ATCC_1997 RVELRPDALYVDDG-DILTSAGLSAGMDLCLHVVRRELGAAAASDLARWN
Mb1966c|M.bovis_AF2122/97 PR-ISGRSGRCRPDLHAQFAEGVDRGWSHRRHRPRAGTGRRRPRHRDCPD
Rv1931c|M.tuberculosis_H37Rv PR-ISGRSGRCRPDLHAQFAEGVDRGWSHRRHRPRAGTGRRRPRHRDCPD
MMAR_2855|M.marinum_M AVDVDPDPIFIRSSPKVWTAAGVTAGIDLALALVEGDHGTEIAQTVARWL
MUL_2902|M.ulcerans_Agy99 AVDVDPDPIFIRSSPKVWTAAGVTAGIDLALALVEGDHGTEIAQTVARWL
MAV_4981|M.avium_104 EITVEPDALFVCDG-DVFTSAGISSGIDLALALVEMDYGTELVRAVARWL
: . . : * * . . *
Mflv_1437|M.gilvum_PYR-GCK VVPPQRDGGQ----RQYIDQ--PIPVKCSERFAPQLDWILANLDKPHTVT
Mvan_5349|M.vanbaalenii_PYR-1 VVPPQRDGGQ----RQYIDQ--PIPVKCSERFAPHLDWILANLDKPHTVT
TH_3120|M.thermoresistible__bu VVPPQRDGGQ----RQFIDQ--PIPVRHSEGFAPHLDWILSNLDKTHTVA
MSMEG_5193|M.smegmatis_MC2_155 VVPPWREGGQ----AQFIDRRLPEPEQATTSTAGTREWALDRLHEELTVE
MAB_2445|M.abscessus_ATCC_1997 VMAPHRDGGQ----AQFIPP--VRTALGAGGLGPTLSWAAERLAEIDDVS
Mb1966c|M.bovis_AF2122/97 GCPLARPVSAPTRWADPVRGSGVDATRQTDLDPPGAGGHRGRAGGAHRIG
Rv1931c|M.tuberculosis_H37Rv GCPLARPVSAPTRWADPVRGSGVDATRQTDLDPPGAGGHRGRAGGAHRIG
MMAR_2855|M.marinum_M VLYLRRPGGQ-TQFAAPVWMP--RAKRPSIRDVQEA--IEAQPGGPHSIE
MUL_2902|M.ulcerans_Agy99 VLYLRRPCGQ-TQFAAPVWMP--RAKRPSIRDVQEA--IEAQPGGPHSIE
MAV_4981|M.avium_104 VVYLKRAGGQ-SQFSALVEAE--PPPRSPLRKVTAA--ISADPAADHSVK
* . : . . :
Mflv_1437|M.gilvum_PYR-GCK SLSRRAHMSGRTFARRFVEETGRTPMQWITDQRVLYARRMLEETTLDIDR
Mvan_5349|M.vanbaalenii_PYR-1 TLARRAHMSGRTFARRFVEETGRTPMQWVTDQRVLFARRMLEETNLDIDR
TH_3120|M.thermoresistible__bu SLARRANMSPRTFARRFVEETGRTPMQWVTDQRVLYARRLLEETDLDIHR
MSMEG_5193|M.smegmatis_MC2_155 RLARHAHMSARTFSRRFAEETGQSPGTWIRNRRIDYARELLESHDLPIDE
MAB_2445|M.abscessus_ATCC_1997 ALARHAHLSLRTFNRRFAEEVGTTPKRWLDVQRATRARELLENTDMTVES
Mb1966c|M.bovis_AF2122/97 ELAQRAAMSPRHFTRVFSDEVGEAPGRYVERIRTEAARRQLEETHDTVVA
Rv1931c|M.tuberculosis_H37Rv ELAQRAAMSPRHFTRVFSDEVGEAPGRYVERIRTEAARRQLEETHDTVVA
MMAR_2855|M.marinum_M ELAHRAAMSPRHFTRVFTGEVGEAPRQYVERVRTEAARRQLEETEDTVVA
MUL_2902|M.ulcerans_Agy99 ELAHRAAMSPRHFTRVFTGEVGEAPGRYVERVRTEAARRQLEETEDTVVA
MAV_4981|M.avium_104 SLSARASLSTRQLTRLFQSELGTTPARYVEMVRIDAARAALDAGR-SVAE
*: :* :* * : * * * * :* :: * ** *: :
Mflv_1437|M.gilvum_PYR-GCK IAEQSGFGTATLLRHHFRRLIGVTPSDYRKRFN-----AHAP-EVAEIA-
Mvan_5349|M.vanbaalenii_PYR-1 IAEQSGFGTATLLRHHFRRIIGVTPSDYRRRFN-----STASQDVAVIA-
TH_3120|M.thermoresistible__bu IAARCGFGSTTLLRHHFRRVIGVTPSDYRRRFACGSTTSGSTESGAEVTD
MSMEG_5193|M.smegmatis_MC2_155 VARLSGLGTAGNLRHHLRRGLGMSPSSYRKVYQ-------GT--------
MAB_2445|M.abscessus_ATCC_1997 IAAQCGFGSVAAMRTHLRRVTATTPSAYRRAFRR----------------
Mb1966c|M.bovis_AF2122/97 IAARCGFGTAETMRRSFIRRVGISPDQYRKAFA-----------------
Rv1931c|M.tuberculosis_H37Rv IAARCGFGTAETMRRSFIRRVGISPDQYRKAFA-----------------
MMAR_2855|M.marinum_M IAARCGFGTAETMRRNFIRRVGISPDQYRKAFA-----------------
MUL_2902|M.ulcerans_Agy99 IAARCGFGTAETMRRNFIRRVGISPDQYRKAFA-----------------
MAV_4981|M.avium_104 SARLAGFGSAETLRRVFVEHLGLSPKAYRDRFRTAARG------------
* .*:*:. :* : . . :*. ** :