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MHTVAILAYDGMSGFESGLAAEIFGMTELSERFSAGLTRPWYTVKLCSESAELRLLGGATVRTAYDLSDL AEADTVVIPSVRDIGDPVSSELVDAIKTADARGARLVSICSGAFALAAAGVLDGHKATTHWIYTDELRET YPGIDIDPNPLYVDNGRVLTSAGCAAGLDLCLHIVRTDHGVRVANDVARRLVISPHRAGGQAQYIETPVP EPTEDGRIAAGMAWALEHLDETITLDELAARSAMSRRSYLRQFAKATGTTPIRWLIEQRIQASLALLESS DHSIDQIAARVGFESTATFRHHFVRQMHTTPSDYRSAFTGS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1693 | - | - | 100% (321) | AraC family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1437 | - | 2e-67 | 41.96% (317) | AraC family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1008 | - | 5e-40 | 36.00% (250) | Fis family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1966c | - | 1e-10 | 38.10% (84) | transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv1931c | - | 1e-10 | 38.10% (84) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0557 | - | 7e-70 | 42.50% (320) | AraC family transcriptional regulator |
| M. marinum M | MMAR_2855 | - | 4e-41 | 37.94% (253) | transcriptional regulatory protein |
| M. avium 104 | MAV_4981 | - | 1e-40 | 33.54% (322) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_5563 | - | 6e-69 | 45.06% (324) | AraC-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3120 | - | 8e-68 | 43.81% (315) | PUTATIVE transcriptional regulator, AraC family with |
| M. ulcerans Agy99 | MUL_2902 | - | 1e-40 | 37.94% (253) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5349 | - | 5e-66 | 40.56% (323) | AraC family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1693|M.gilvum_PYR-GCK -------MHTVAILAYDGMSGFESGLAAEIFGMTELSERFSAGLTRPWYT
MSMEG_5563|M.smegmatis_MC2_155 -------MHRVVVLVRDGMIPLEVGIPHRLFGQAR-----STSGERLYDV
TH_3120|M.thermoresistible__bu ----------VAALVLDGLAIFEFGVICEVFGVDR----TDDGVPPVDFT
Mvan_5349|M.vanbaalenii_PYR-1 -----MAIRSVSALVLDNLAMFEFGVICEVFGIDR----SADGVPNFDFK
MAB_0557|M.abscessus_ATCC_1997 ------MLRSVAALVLDRVAVFEFGVICEVFGIDR----ARDGVPNFDFR
Mb1966c|M.bovis_AF2122/97 ----------MVIVGFPG--------------------------------
Rv1931c|M.tuberculosis_H37Rv ----------MVIVGFPG--------------------------------
MMAR_2855|M.marinum_M ------MARKVVIVGFPGVQPLDVVGPFEVFAGAS------LLSEGGYDV
MUL_2902|M.ulcerans_Agy99 ------MARKVVTVGFPGVQPLDVVGPFEVFAGAS------LLSEGGYDV
MAV_4981|M.avium_104 MADSSATPRVVVIVVFDDVTMLDVAGAGEVFAEAN------RFG-ADYLL
: :
Mflv_1693|M.gilvum_PYR-GCK VKLCSESAELRLLGGATVRTAYDLSDLAEADTVVIPSVR-DIGDPVSSEL
MSMEG_5563|M.smegmatis_MC2_155 VTATLTPGPVRTDTDFTINVANGPDVLAQADTVVIPASDEDYAPPTQGRL
TH_3120|M.thermoresistible__bu VCGPRAGQPVRTSFGATLTPDSGLDGLAGADLVAIPAIR--QDD-YLPEA
Mvan_5349|M.vanbaalenii_PYR-1 VCGPEAGSPLRTSVGATIIPDHGLDHLVGADLVAIPAIG--GSD-YLPEA
MAB_0557|M.abscessus_ATCC_1997 VCGVEPGVPLRTTVGASLIPDHGLEGLADADLVALPARP--FTEGYPQEA
Mb1966c|M.bovis_AF2122/97 ---------------------------DPVDTVILPGGAGVDAARSEPAL
Rv1931c|M.tuberculosis_H37Rv ---------------------------DPVDTVILPGGAGVDAARSEPAL
MMAR_2855|M.marinum_M ALASIDERPVATGIGLEFMTTRLPDPSAPVDTVVLPGGGGVDAARDNVAL
MUL_2902|M.ulcerans_Agy99 ALASIDERPVATGIGLEFMTTRLPDPSAPVDTVVLPGGGGVDAARDNVAL
MAV_4981|M.avium_104 KIASVDGRDVTTSIGTRLGVTDAVSSIESADTVLVAGSDNLPRRPIDPEL
.* * :..
Mflv_1693|M.gilvum_PYR-GCK VDAIKTADAR---GARLVSICSGAFALAAAGVLDGHKATTHWIYTDELRE
MSMEG_5563|M.smegmatis_MC2_155 SPELATALSHIKPGTRMASICTGSFVLAAAGLLDERRATTHWRSAGDFRR
TH_3120|M.thermoresistible__bu LDAVRAAADA---GAIILTVCSGAFLAGAAGLLDGRPCTTHWGLTEELAR
Mvan_5349|M.vanbaalenii_PYR-1 LDAVRRAAES---GSIILTVCSGAFVAGAAGLLDGRPCTTHWMHADELAR
MAB_0557|M.abscessus_ATCC_1997 LDAVRAASER---GATILTVCSGAFIAGAAGLLDGRRCTTHWMYTDTLAR
Mb1966c|M.bovis_AF2122/97 IDWVKAVSGT---ARRVVTVCTGAFLAAEAGLLG--RTPSDDALG--LCR
Rv1931c|M.tuberculosis_H37Rv IDWVKAVSGT---ARRVVTVCTGAFLAAEAGLLG--RTPSDDALG--LCR
MMAR_2855|M.marinum_M MDWVKAAAGT---ARRVVTVCTGTFLAAEAGLLDGCRATTHWAFADRLAR
MUL_2902|M.ulcerans_Agy99 MDWVKAAAGT---ARRVVTVCTGTFLAAEAGLLDGCRATTHWAFADRLAR
MAV_4981|M.avium_104 VEAVKSVADR---TRRLASICTGSFILGQAGLLDGRRATTHWHDVRLFAR
: . : ::*:*:* . **:*. .:. : .
Mflv_1693|M.gilvum_PYR-GCK TYPGIDIDPNPLYVDNG-RVLTSAGCAAGLDLCLHIVRTDHGVRVANDVA
MSMEG_5563|M.smegmatis_MC2_155 LFPHIELDPNVLFTDCD-DVLTSAGVAAGLDLCLHMIRSDFGAAVANEVA
TH_3120|M.thermoresistible__bu RYPTARVDRNVLYVDDG-DLITSAGTAAGIDACLHLVRRELGSEVTNTIA
Mvan_5349|M.vanbaalenii_PYR-1 MYPTAKVDRNVLFVDDG-NLITSAGTAAGIDACLHLVRRELGSEVTNKIA
MAB_0557|M.abscessus_ATCC_1997 QYPTATVDRDVLFVDDG-DLITSAGTAAGIDACLHLVRRELGSEITNRIA
Mb1966c|M.bovis_AF2122/97 TFRPR-ISGRSGRCRPDLHAQFAEGVDRGWSHRRHRPRAGTGRRRPRHRD
Rv1931c|M.tuberculosis_H37Rv TFRPR-ISGRSGRCRPDLHAQFAEGVDRGWSHRRHRPRAGTGRRRPRHRD
MMAR_2855|M.marinum_M EFPAVDVDPDPIFIRSSPKVWTAAGVTAGIDLALALVEGDHGTEIAQTVA
MUL_2902|M.ulcerans_Agy99 EFPAVDVDPDPIFIRSSPKVWTAAGVTAGIDLALALVEGDHGTEIAQTVA
MAV_4981|M.avium_104 AFPEITVEPDALFVCDG-DVFTSAGISSGIDLALALVEMDYGTELVRAVA
: :. . : * * . . * .
Mflv_1693|M.gilvum_PYR-GCK RRLVISPHRAGGQAQYIETPVPEPTEDGRIAAGMAWALEH-----LDETI
MSMEG_5563|M.smegmatis_MC2_155 RGTVTPPHREGGQAQYIQRLVPEPT-TAATGAARAWAAER-----LDEAI
TH_3120|M.thermoresistible__bu RHMVVPPQRDGGQRQFIDQPIPVRH-SEGFAPHLDWILSN-----LDKTH
Mvan_5349|M.vanbaalenii_PYR-1 RRMVVPPQRDGGQRQYIDQPIPVKC-SERFAPHLDWILAN-----LDKPH
MAB_0557|M.abscessus_ATCC_1997 RRMVVPPQRAGGQRQFIPQPVPDMV-ADGFGELCDWLIEN-----IDQSH
Mb1966c|M.bovis_AF2122/97 CPDGCPLARPVSAPTRWADPVRGSGVDATRQTDLDPPGAGGHRGRAGGAH
Rv1931c|M.tuberculosis_H37Rv CPDGCPLARPVSAPTRWADPVRGSGVDATRQTDLDPPGAGGHRGRAGGAH
MMAR_2855|M.marinum_M RWLVLYLRRPGGQ-TQFAAPVWMP--RAKRPSIRDVQEA--IEAQPGGPH
MUL_2902|M.ulcerans_Agy99 RWLVLYLRRPCGQ-TQFAAPVWMP--RAKRPSIRDVQEA--IEAQPGGPH
MAV_4981|M.avium_104 RWLVVYLKRAGGQ-SQFSALVEAE--PPPRSPLRKVTAA--ISADPAADH
* . :
Mflv_1693|M.gilvum_PYR-GCK TLDELAARSAMSRRSYLRQFAKATGTTPIRWLIEQRIQASLALLESSDHS
MSMEG_5563|M.smegmatis_MC2_155 TLDDMAAVSAMSKRTFTRRFRAETGLSPMQWLTEQRLHRACELLEQTDFP
TH_3120|M.thermoresistible__bu TVASLARRANMSPRTFARRFVEETGRTPMQWVTDQRVLYARRLLEETDLD
Mvan_5349|M.vanbaalenii_PYR-1 TVTTLARRAHMSGRTFARRFVEETGRTPMQWVTDQRVLFARRMLEETNLD
MAB_0557|M.abscessus_ATCC_1997 TVAELAARVHMSTRTFARKFTDQTGVTPMRWIIDQRVLRARRLLEETGLD
Mb1966c|M.bovis_AF2122/97 RIGELAQRAAMSPRHFTRVFSDEVGEAPGRYVERIRTEAARRQLEETHDT
Rv1931c|M.tuberculosis_H37Rv RIGELAQRAAMSPRHFTRVFSDEVGEAPGRYVERIRTEAARRQLEETHDT
MMAR_2855|M.marinum_M SIEELAHRAAMSPRHFTRVFTGEVGEAPRQYVERVRTEAARRQLEETEDT
MUL_2902|M.ulcerans_Agy99 SIEELAHRAAMSPRHFTRVFTGEVGEAPGRYVERVRTEAARRQLEETEDT
MAV_4981|M.avium_104 SVKSLSARASLSTRQLTRLFQSELGTTPARYVEMVRIDAARAALDAGR-S
: :: :* * * * * :* ::: * : *:
Mflv_1693|M.gilvum_PYR-GCK IDQIAARVGFESTATFRHHFVRQMHTTPSDYRSAFTGS------------
MSMEG_5563|M.smegmatis_MC2_155 VERVAAESGLGSGTAMRQLFQSAMGVTPSAYRATFRGRELSSGDG-----
TH_3120|M.thermoresistible__bu IHRIAARCGFGSTTLLRHHFRRVIGVTPSDYRRRFACGSTTSGSTESGAE
Mvan_5349|M.vanbaalenii_PYR-1 IDRIAEQSGFGTATLLRHHFRRIIGVTPSDYRRRFN--STASQDVAVIA-
MAB_0557|M.abscessus_ATCC_1997 IDTVAARSGFGTAILLRHHFRRGVGITPTDYRKAFAVAAR----------
Mb1966c|M.bovis_AF2122/97 VVAIAARCGFGTAETMRRSFIRRVGISPDQYRKAFA--------------
Rv1931c|M.tuberculosis_H37Rv VVAIAARCGFGTAETMRRSFIRRVGISPDQYRKAFA--------------
MMAR_2855|M.marinum_M VVAIAARCGFGTAETMRRNFIRRVGISPDQYRKAFA--------------
MUL_2902|M.ulcerans_Agy99 VVAIAARCGFGTAETMRRNFIRRVGISPDQYRKAFA--------------
MAV_4981|M.avium_104 VAESARLAGFGSAETLRRVFVEHLGLSPKAYRDRFRTAARG---------
: * *: : :*: * : :* ** *
Mflv_1693|M.gilvum_PYR-GCK ---
MSMEG_5563|M.smegmatis_MC2_155 ---
TH_3120|M.thermoresistible__bu VTD
Mvan_5349|M.vanbaalenii_PYR-1 ---
MAB_0557|M.abscessus_ATCC_1997 ---
Mb1966c|M.bovis_AF2122/97 ---
Rv1931c|M.tuberculosis_H37Rv ---
MMAR_2855|M.marinum_M ---
MUL_2902|M.ulcerans_Agy99 ---
MAV_4981|M.avium_104 ---