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VSQPKDLPRTVGELRASGHRERGVKAEIRENLLAALAERRDVWPGILGFEDTVIPQLERALIAGHDVVLL GERGQGKTRLLRALTGLLDEWTPVIAGSELGEHPYSPITPESIRRAADSGDDLPVEWRHRSERYTEKLAT PDTSVADLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAERIQVAMLNVMEERDIQVR GYTLRLPLDVLVVASANPEDYTNRGRIITPLKDRFGAEIRTHYPLELEAEVGVIRQEAELAAEVPEYLLA VLARFARNLRESNSIDQRSGVSARFAIAAAETVAASARHRAAILGEDDPVARVVDLGTVIDVLRGKLEFE TGEEGREQAVLEHLLRRATADTAQRLLGGIDVGPLVAAIEEGSPVTTGERVSAKDVVAALPDLPAIDAIA HRLNAVSVGQRAAAIELALEALYLAKRIDKVSGEGETVYG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5512 | - | - | 100% (461) | magnesium chelatase |
| M. smegmatis MC2 155 | MSMEG_6612 | moxR | 2e-05 | 30.11% (93) | ATPase, MoxR family protein |
| M. smegmatis MC2 155 | MSMEG_3867 | - | 3e-05 | 26.28% (137) | ATPase family protein associated with various cellular |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0983 | - | 0.0 | 86.87% (457) | magnesium chelatase |
| M. gilvum PYR-GCK | Mflv_1877 | - | 0.0 | 86.83% (463) | putative magnesium chelatase |
| M. tuberculosis H37Rv | Rv0958 | - | 0.0 | 86.65% (457) | magnesium chelatase |
| M. leprae Br4923 | MLBr_01810 | moxR | 2e-05 | 24.06% (187) | MoxR homolog |
| M. abscessus ATCC 19977 | MAB_2726c | - | 5e-07 | 26.33% (281) | hypothetical protein MAB_2726c |
| M. marinum M | MMAR_4541 | - | 0.0 | 86.39% (463) | magnesium chelatase |
| M. avium 104 | MAV_3299 | - | 3e-06 | 26.60% (188) | MoxR protein |
| M. thermoresistible (build 8) | TH_1334 | - | 0.0 | 92.61% (460) | POSSIBLE MAGNESIUM CHELATASE |
| M. ulcerans Agy99 | MUL_4711 | - | 0.0 | 86.64% (464) | magnesium chelatase |
| M. vanbaalenii PYR-1 | Mvan_4854 | - | 0.0 | 88.34% (463) | putative magnesium chelatase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5512|M.smegmatis_MC2_155 MVSQPKDLPRTVGELRASGHRERGVKAEIRENLLAALAERR---DVWPGI
TH_1334|M.thermoresistible__bu -VTQPNDLPRTVGELRASGHRERGVKQEIRENLLAALAGGR---DVWPGI
Mflv_1877|M.gilvum_PYR-GCK -MTSPNDLPRTVGELRASGHRERTVKAEIRENLLAALASGAPVDEVWPGI
Mvan_4854|M.vanbaalenii_PYR-1 -MTSPNDLPRTVGELRASGHQERSIKAEIRENLLSALASGAGADAVWPGI
Mb0983|M.bovis_AF2122/97 --MSPSNLPRTVGELRAAGHRERGVKQEIRENLLTALADGDN---VWPGI
Rv0958|M.tuberculosis_H37Rv --MSPSNLPRTVGELRAAGHRERGVKQEIRENLLTALADGDN---VWPGI
MMAR_4541|M.marinum_M -MTSPSNLPRTVGELRASGHRERGVKQEIRENLLTALADGPDNAAVWPGI
MUL_4711|M.ulcerans_Agy99 MVTSPSNLPRTVGELRASGHRERGVKQEIRENLLTALADGPDNAAVWPGI
MLBr_01810|M.leprae_Br4923 -MTSAGGLPVGADGCSGPGGQSGPRAHEAPP--------------GGA--
MAV_3299|M.avium_104 -MTAAGGPPPGAGGYSGPGGQSGPGAHEAPT--------------GGAGA
MAB_2726c|M.abscessus_ATCC_199 -MSSPG-QPGGGAGYTGGSAGSAPHAPQGAT--------------SPA--
. * . . . : .
MSMEG_5512|M.smegmatis_MC2_155 LGFEDTVIPQLERALIAGHDVVLLGERGQGKTRLLRALTGLLDEWTPVIA
TH_1334|M.thermoresistible__bu LGFEDTVIPQLERALIAGHDVVLLGERGQGKTRLLRALIGLLDEWTPVIA
Mflv_1877|M.gilvum_PYR-GCK LGFEDTVLPQLERALIAGHDIVLLGERGQGKTRLLRGLTGMLDEWTPVIA
Mvan_4854|M.vanbaalenii_PYR-1 LGFEDTVIPQLERALIAGHDVVLLGERGQGKTRLLRALTNLLDEWTPVIA
Mb0983|M.bovis_AF2122/97 LGFDDTVIPQVERALIAGHDFVLLGERGQGKTRLLRALAGLLDEWTPVIA
Rv0958|M.tuberculosis_H37Rv LGFDDTVIPQVERALIAGHDFVLLGERGQGKTRLLRALAGLLDEWTPVIA
MMAR_4541|M.marinum_M VGFDDTVIPQLERALIAGHDFVLLGERGQGKTRLLRALTGLLDEWTPVIA
MUL_4711|M.ulcerans_Agy99 VGFDDTVIPQLERALIAGHDFVLLGERGQGKTRLLRALTGLLDEWTPVIA
MLBr_01810|M.leprae_Br4923 -DGLVAEVHTLERAIFEVKRVIVGQDQ-----LVERMLVGLLSKGHVLLE
MAV_3299|M.avium_104 GNGLAAEVQTLERAIFEVKRIIVGQDQ-----LVERMLVGLLSKGHVLLE
MAB_2726c|M.abscessus_ATCC_199 ---LAAEVQNLERAIFEVKRIIVGQDR-----LVERILVGLLAKGHVLLE
: : :***:: : .:: :: : * * .:* : ::
MSMEG_5512|M.smegmatis_MC2_155 GSELGEHPYSPITPESIRRAADSGDDLPVEWRHRSERYTEKLATPDTSVA
TH_1334|M.thermoresistible__bu GSELGEHPYSPITPESIRRAADSGDDLPITWRHRSERYTEKLATPDTSVA
Mflv_1877|M.gilvum_PYR-GCK GAELGEHPYSPITPESIRRAADFGDDLPIAWRHRSERYTEKLATPDTSVA
Mvan_4854|M.vanbaalenii_PYR-1 GAELGEHPYSPITPESIRRAADSGDDLPITWRHRSERYTEKLATPDTSVA
Mb0983|M.bovis_AF2122/97 GAELGEHPYTPITPESIRRAAQLGDDLPVAWKHRSERYTEKLATPDTSVA
Rv0958|M.tuberculosis_H37Rv GAELGEHPYTPITPESIRRAAQLGDDLPVAWKHRSERYTEKLATPDTSVA
MMAR_4541|M.marinum_M GAELPEHPYRPITPESIRRAAQLKDDLPVAWKHRSERYTEKLATPDTSVA
MUL_4711|M.ulcerans_Agy99 GAELPEHPYRPITPESIRRAAQLKDDLPVAWKHRSERYTEKLATPDTSVA
MLBr_01810|M.leprae_Br4923 GVPG---VAKTLAVETFARVVG-------------GTFARIQFTPDLVPT
MAV_3299|M.avium_104 GVPG---VAKTLAVETFAKVVG-------------GTFARIQFTPDLVPT
MAB_2726c|M.abscessus_ATCC_199 GVPG---VAKTLAVETFAKVVG-------------GTFSRIQFTPDLVPT
* .:: *:: :.. ::. *** :
MSMEG_5512|M.smegmatis_MC2_155 DLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAERIQV
TH_1334|M.thermoresistible__bu DLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAERIQV
Mflv_1877|M.gilvum_PYR-GCK DLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAERIQV
Mvan_4854|M.vanbaalenii_PYR-1 DLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAERIQV
Mb0983|M.bovis_AF2122/97 DLVGDVDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAERIQV
Rv0958|M.tuberculosis_H37Rv DLVGDVDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAERIQV
MMAR_4541|M.marinum_M DLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAERIQV
MUL_4711|M.ulcerans_Agy99 DLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAERIQV
MLBr_01810|M.leprae_Br4923 DIIG---TRIYRQGK-----EEFDTELGPVVVN-FLLADEINRAPAKVQS
MAV_3299|M.avium_104 DIIG---TRIYRQGK-----EEFDTELGPVVVN-FLLADEINRAPAKVQS
MAB_2726c|M.abscessus_ATCC_199 DIIG---TRIYRQGR-----EEFDTELGPVVAN-FLLADEINRAPAKVQS
*::* . :*: * : * * . . :: .:*: . ::*
MSMEG_5512|M.smegmatis_MC2_155 AMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLKDRFG
TH_1334|M.thermoresistible__bu AMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLKDRFG
Mflv_1877|M.gilvum_PYR-GCK AMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLKDRFG
Mvan_4854|M.vanbaalenii_PYR-1 AMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLKDRFG
Mb0983|M.bovis_AF2122/97 SMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPIKDRFG
Rv0958|M.tuberculosis_H37Rv SMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPIKDRFG
MMAR_4541|M.marinum_M SMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLKDRFG
MUL_4711|M.ulcerans_Agy99 SMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLKDRFG
MLBr_01810|M.leprae_Br4923 ALLEVMQERHVSIGGKTFPLPNPFLVMATQNPIEHEGVYLLPEAQRDRFL
MAV_3299|M.avium_104 ALLEVMQERHVSIGGKTFPLPNPFLVMATQNPIEHEGVYPLPEAQRDRFL
MAB_2726c|M.abscessus_ATCC_199 ALLEVMAERKISIGGKDYHLPKPFLVMATQNPIENEGVYPLPEAQRDRFL
::*:** **.:.: * ** .**:*: ** : . : . :***
MSMEG_5512|M.smegmatis_MC2_155 AEIRTHYPLELEAEVGVIRQEAELAAEVPEYLLAVLARFARNLRESNSID
TH_1334|M.thermoresistible__bu AEIRTHYPQQLEAEVGVITQEAHLAAEVPEYLLHILARFTRNLRESPSID
Mflv_1877|M.gilvum_PYR-GCK AEIRTHYPLELDAEVGVIVQEAHMAAEVPDYLLQILARFARALRESSSVD
Mvan_4854|M.vanbaalenii_PYR-1 AEIRTHYPPELDAEVGVITQEAHLAAEVPDYLLQILARFARSLRESSSID
Mb0983|M.bovis_AF2122/97 AEIRTHYPLELEAEMGVIVQEAHLSAQVPDYLMQVLARFARYLRESRSID
Rv0958|M.tuberculosis_H37Rv AEIRTHYPLELEAEMGVIVQEAHLSAQVSDYLMQVLARFARYLRESRSID
MMAR_4541|M.marinum_M AEIRTHYPLELEAEMGVIAQEAHLSAQVPEYLLQVIARFARYLRESSSVD
MUL_4711|M.ulcerans_Agy99 AEIRTHYPLELEAEMGVIAQEAHLSAQVPDYLLQVIARFARYLRESSSVD
MLBr_01810|M.leprae_Br4923 FKINVGYPSPEEERE--IIYRMGVTPPVPKQILNAGDLLRLQEISANNFV
MAV_3299|M.avium_104 FKINVGYPSPEEERE--IIYRMGVRPPEPKQILNTGDLVRLQDIAANVFV
MAB_2726c|M.abscessus_ATCC_199 FKINVDYPTVEEERE--IIYRMGVTPPEPKQILSSEALLRLQDLAANNFV
:*.. ** : . * . : . .. :: . : .
MSMEG_5512|M.smegmatis_MC2_155 QRSGVSARFAIAAAETVAASARHRAAILGEDDPVARVVDLGTVIDVLRGK
TH_1334|M.thermoresistible__bu QRSGVSARFAIAAAETVAASARHRSAILGEDDPVARVVDLGTVIEVLRGK
Mflv_1877|M.gilvum_PYR-GCK QRSGVSARFAIAAAETVAASARHRAAVLNEQEPVARVVDLASILDVLRGK
Mvan_4854|M.vanbaalenii_PYR-1 QRSGVSARFAIAAAETVAASARHRAALLGEQDPVARVVDLQNVIDVLRGK
Mb0983|M.bovis_AF2122/97 QRSGVSARFAIAAAETVAAAARHRGAVLGETDPVARVVDLGTVIDVLRGK
Rv0958|M.tuberculosis_H37Rv QRSGVSARFAIAAAETVAAAARHRGAVLGETDPVARVVDLGTVIDVLRGK
MMAR_4541|M.marinum_M QRSGVSARFAIAAAETVAAAARHRGAVLGETDPVARVVDLSTVIDVLRGK
MUL_4711|M.ulcerans_Agy99 QRSGVSARFAIAAAETVAAAARHRGAVLGETDPVARVVDLGTVIDVLRGK
MLBr_01810|M.leprae_Br4923 HHALVDYVVRVVTATRHPEQLGMNDVKTWISFGASPRASLG-IIKASR-S
MAV_3299|M.avium_104 HHALVDYVVRVVTATRHPEQLGMNDVKTWISFGASPRASLG-IIAGAR-S
MAB_2726c|M.abscessus_ATCC_199 HHALVDYVVRVIAATRNPAQFGLGDVANWISYGASPRASLG-IIASAR-A
::: *. . : :* . . .: ..* :: *
MSMEG_5512|M.smegmatis_MC2_155 LEFETGEEGREQAVLEHLLRRATADTAQRLLGGIDVGPLVAAIEEGSPVT
TH_1334|M.thermoresistible__bu LEFESGEEGRELAILEHLLRRATADTAQRLLGGIDVGPLVAAVEEGSPVT
Mflv_1877|M.gilvum_PYR-GCK LEFESGEEGREQAILEHLLRRATAETAQRLLGGIDVGPIVTAVEGGSPVT
Mvan_4854|M.vanbaalenii_PYR-1 LEFESGEEGREQAVLEHLLRRATAETAQRLLGGIDVGPIVTAVENGSPVT
Mb0983|M.bovis_AF2122/97 LEFESGEEGREQAVLEHLLRRATADTASRVLGGIDVGSLVTAVEGGSAVT
Rv0958|M.tuberculosis_H37Rv LEFESGEEGREQAVLEHLLRRATADTASRVLGGIDVGSLVTAVEGGSAVT
MMAR_4541|M.marinum_M LEFESGEEGREQAVLEHLLRRATADTASRALGGIDVGTLVSAVEGGSAVT
MUL_4711|M.ulcerans_Agy99 LEFESGEEGREQAVLEHLLRRATADTASRALGGIDVGTLVSAVEGGSAVT
MLBr_01810|M.leprae_Br4923 LALVRGRD--------YVIPQDVIEVIPDVLRHRLVLTYNALADEISPEI
MAV_3299|M.avium_104 LALVRGRD--------YVIPQDVVDVIPDVLRHRLVLTYDALADEISPEI
MAB_2726c|M.abscessus_ATCC_199 LALVRGRD--------YVIPQDVIEVIPDVLRHRLVMSYDALADEVSADT
* : *.: ::: : . :. * * . : : *.
MSMEG_5512|M.smegmatis_MC2_155 TGERVSAKDVVAALPDLPAIDAIAHRLNAVSVGQRAAAIELALEALYLAK
TH_1334|M.thermoresistible__bu TGERVSAKDVLAALPDLPVIDTITTRLGAQSIGQRAAAVELALEALYLAK
Mflv_1877|M.gilvum_PYR-GCK TGDRVSARDVLAALPEVSAVAEIQQRLGAQTDGQRAAAIELALEALYLAK
Mvan_4854|M.vanbaalenii_PYR-1 TGERVSAREVLAAVPEVSAVAEIQQRLGATSEGQRAAAMELALEALYLAK
Mb0983|M.bovis_AF2122/97 TGERVSAKDVLAAVPGLPVVDRIARKLGAESEGERAAALELALEALYLAK
Rv0958|M.tuberculosis_H37Rv TGERVSAKDVLAAVPGLPVVDRIARKLGAESEGERAAALELALEALYLAK
MMAR_4541|M.marinum_M TGERVSAKDVLAAVPGLPVVETIARKLDAESEGERAAALELALEALYLAK
MUL_4711|M.ulcerans_Agy99 TGERVSAKDVLAAVPGLPVVETIARKLNAESEGERAAALELALEALYLAK
MLBr_01810|M.leprae_Br4923 VINRVLQTVALPQVNSFPQQGHSVPSVTQ-------AAAAASGR------
MAV_3299|M.avium_104 VINRVLQTVALPQVNAVPQQGHSVPPVMQ-------PAGAASGR------
MAB_2726c|M.abscessus_ATCC_199 AINRILQTVGLPQVNAVPQQGNSVPPAMVGTNNPVPAAHNAAPR------
. :*: :. : .. .* : .
MSMEG_5512|M.smegmatis_MC2_155 RIDKVSGEGETVYG
TH_1334|M.thermoresistible__bu RIDKQTGEGETIYG
Mflv_1877|M.gilvum_PYR-GCK RIDKVSDQGETVYG
Mvan_4854|M.vanbaalenii_PYR-1 RIDKVSDEGETVYG
Mb0983|M.bovis_AF2122/97 RVDKVCGEGQTVYG
Rv0958|M.tuberculosis_H37Rv RVDKVCGEGQTVYG
MMAR_4541|M.marinum_M RVDKVSGEGQTVYG
MUL_4711|M.ulcerans_Agy99 RVDKVSGEGQTVYG
MLBr_01810|M.leprae_Br4923 --------------
MAV_3299|M.avium_104 --------------
MAB_2726c|M.abscessus_ATCC_199 --------------