For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_6612 (moxR)

annotation: ATPase, MoxR family protein
coordinates: 6664363 - 6665364
length: 333

TAPRLQLDQRDVAEAQQIVGAVTSAFSAKVVGQDHLRESMLVALLSGGHLLLESVPGLAKTTAARVIAES
IDGSFHRIQCTPDLLPSDIIGTQVYEAATHSFTTQLGPVHANIVLLDEINRSSAKTQSAMLEAMEERQTT
IAGVEYPIPEPFLVIATQNPVDQEGTYPLSEAQTDRFMLKEIVRYPSVADEVEMIARMDAGLYERGRHGT
PVVGIDDVRRVQRIAESVHLDRALVEYAGRLVGVTREPDSFLPTNLARLVEYGASPRATIALCRTARALA
LLRGRDHVVPDDIARLAHRVLRHRLILGFEAASARITPDVVIDAVLAAVRVP*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_6612moxR-100% (333)ATPase, MoxR family protein
M. smegmatis MC2 155MSMEG_3147moxR9e-7646.86% (303) ATPase, MoxR family protein
M. smegmatis MC2 155MSMEG_6219-6e-6441.49% (323) ATPase family protein associated with various cellular

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1515moxR12e-7848.84% (303) transcriptional regulatory protein MOXR1
M. gilvum PYR-GCKMflv_0039-1e-14275.68% (333) ATPase
M. tuberculosis H37RvRv1479moxR12e-7848.84% (303) transcriptional regulatory protein MOXR1
M. leprae Br4923MLBr_01810moxR2e-7646.04% (328) MoxR homolog
M. abscessus ATCC 19977MAB_0653-1e-12063.75% (331) MoxR-like ATPase
M. marinum MMMAR_2286moxR12e-7848.84% (303) transcriptional regulatory protein, MoxR1
M. avium 104MAV_3299-7e-7947.83% (322) MoxR protein
M. thermoresistible (build 8)TH_0628moxR1e-13772.97% (333) ATPase, MoxR family protein
M. ulcerans Agy99MUL_1488moxR11e-7848.84% (303) transcriptional regulatory protein, MoxR1
M. vanbaalenii PYR-1Mvan_0879-1e-14177.33% (322) ATPase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_2286|M.marinum_M               MTSAGG------GYSGPGGHSAPPAHEAPSGGP---DGLAAEVHTLERAI
MUL_1488|M.ulcerans_Agy99           MTSAGG------GYSGPGGHSAPPAHEAPSGGP---DGLAAEVHTLERAI
Mb1515|M.bovis_AF2122/97            MTSAGGFPAGAGGYQTPGGHSASPAHEAPPGGA---EGLAAEVHTLERAI
Rv1479|M.tuberculosis_H37Rv         MTSAGGFPAGAGGYQTPGGHSASPAHEAPPGGA---EGLAAEVHTLERAI
MLBr_01810|M.leprae_Br4923          MTSAGGLPVGADGCSGPGGQSGPRAHEAPPGGA---DGLVAEVHTLERAI
MAV_3299|M.avium_104                MTAAGGPPPGAGGYSGPGGQSGPGAHEAPTGGAGAGNGLAAEVQTLERAI
Mflv_0039|M.gilvum_PYR-GCK          MTAAPMP-----------RES-DDAREAQ------------RVVAALSEA
Mvan_0879|M.vanbaalenii_PYR-1       MNAAPLP-----------RDSTDDAREAQ------------RVVAALADA
MSMEG_6612|M.smegmatis_MC2_155      MTAPRLQ-----------LDQ-RDVAEAQ------------QIVGAVTSA
TH_0628|M.thermoresistible__bu      MTAARLQ-----------LNR-EDLEEAR------------RIVDAVSAA
MAB_0653|M.abscessus_ATCC_1997      MTAATQT-----------QPSRQELDQAR------------AVIQAVARA
                                    *.:.                      :*              :       

MMAR_2286|M.marinum_M               FEVKRIIVGQDQLVERMLVGLLAKGHVLLEGVPGVAKTLAVETFARVVGG
MUL_1488|M.ulcerans_Agy99           FEVKRIIVGQDQLVERMLVGLLAKGHVLLEGVPGVAKTLAVETFARVVGG
Mb1515|M.bovis_AF2122/97            FEVKRIIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLAVETFARVVGG
Rv1479|M.tuberculosis_H37Rv         FEVKRIIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLAVETFARVVGG
MLBr_01810|M.leprae_Br4923          FEVKRVIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLAVETFARVVGG
MAV_3299|M.avium_104                FEVKRIIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLAVETFAKVVGG
Mflv_0039|M.gilvum_PYR-GCK          FSAK--VVGQEHLRETLLIGLLTGGHILLESVPGLAKTTAARVIAESIDG
Mvan_0879|M.vanbaalenii_PYR-1       FSAK--VVGQEHLRETLLIGLLTGGHILLESVPGLAKTTAARVVAEAIDG
MSMEG_6612|M.smegmatis_MC2_155      FSAK--VVGQDHLRESMLVALLSGGHLLLESVPGLAKTTAARVIAESIDG
TH_0628|M.thermoresistible__bu      FSQK--VVGQHDLRESLLISLLAGGHILLESVPGLAKTTAARVIADTIHG
MAB_0653|M.abscessus_ATCC_1997      FSVK--VVGQSGLQQSLLIGLLTGGHVLLESVPGLAKTTAARAIADAIQA
                                    *. *  :***  * : :*:.**: **:***.***:*** *....*  : .

MMAR_2286|M.marinum_M               SFARIQFTPDLVPTDIVGTRIYRQGKEEFDTELGPVVANFLLADEINRAP
MUL_1488|M.ulcerans_Agy99           SFARIQFTPDLVPTDIVGTRIYRQGKEEFDTELGPVVANFLLADEINRAP
Mb1515|M.bovis_AF2122/97            TFSRIQFTPDLVPTDIIGTRIYRQGREEFDTELGPVVANFLLADEINRAP
Rv1479|M.tuberculosis_H37Rv         TFSRIQFTPDLVPTDIIGTRIYRQGREEFDTELGPVVANFLLADEINRAP
MLBr_01810|M.leprae_Br4923          TFARIQFTPDLVPTDIIGTRIYRQGKEEFDTELGPVVVNFLLADEINRAP
MAV_3299|M.avium_104                TFARIQFTPDLVPTDIIGTRIYRQGKEEFDTELGPVVVNFLLADEINRAP
Mflv_0039|M.gilvum_PYR-GCK          EFRRIQCTPDLLPSDIIGTQVYDATTTAFVTQLGPVHANVVLLDEINRSS
Mvan_0879|M.vanbaalenii_PYR-1       QFRRIQCTPDLLPSDIIGTQVYDAATTSFVTQLGPVHANVVLLDEINRSS
MSMEG_6612|M.smegmatis_MC2_155      SFHRIQCTPDLLPSDIIGTQVYEAATHSFTTQLGPVHANIVLLDEINRSS
TH_0628|M.thermoresistible__bu      GFQRIQCTPDLLPSDIIGTQVYDAATNAFVTRLGPVHTNIVLLDEINRSS
MAB_0653|M.abscessus_ATCC_1997      QFRRIQCTPDLLPSDIIGTQIFDASKGTFKTQLGPVHANIVLLDEINRSS
                                     * *** ****:*:**:**:::      * *.**** .*.:* *****:.

MMAR_2286|M.marinum_M               AKVQSALLEVMAERHVSIGGKTFPMPNPFLVMATQNPIEQEGVYPLPEAQ
MUL_1488|M.ulcerans_Agy99           AKVQSALLEVMAERHVSIGGKTFPMPNPFLVMATQNPIEQEGVYPLPEAQ
Mb1515|M.bovis_AF2122/97            AKVQSALLEVMQERHVSIGGRTFPMPSPFLVMATQNPIEHEGVYPLPEAQ
Rv1479|M.tuberculosis_H37Rv         AKVQSALLEVMQERHVSIGGRTFPMPSPFLVMATQNPIEHEGVYPLPEAQ
MLBr_01810|M.leprae_Br4923          AKVQSALLEVMQERHVSIGGKTFPLPNPFLVMATQNPIEHEGVYLLPEAQ
MAV_3299|M.avium_104                AKVQSALLEVMQERHVSIGGKTFPLPNPFLVMATQNPIEHEGVYPLPEAQ
Mflv_0039|M.gilvum_PYR-GCK          AKTQSAMLEAMEERQTTIAGTVYPIPEPFLVIATQNPVDQEGTYALSEAQ
Mvan_0879|M.vanbaalenii_PYR-1       AKTQSAMLEAMEERQTTIAGVVYPIPEPFLVIATQNPVDQEGTYALSEAQ
MSMEG_6612|M.smegmatis_MC2_155      AKTQSAMLEAMEERQTTIAGVEYPIPEPFLVIATQNPVDQEGTYPLSEAQ
TH_0628|M.thermoresistible__bu      AKTQSAMLEAMEERQTTIAGTVYPIPEPFLVIATQNPVDQEGTYPLSEAQ
MAB_0653|M.abscessus_ATCC_1997      AKTQSAMLEAMEERQTSIAGEIYKIPEPFLVLATQNPVDQEGTYPLPEAQ
                                    **.***:**.* **:.:*.*  : :*.****:*****:::**.* *.***

MMAR_2286|M.marinum_M               RDRFLFKINVGYPTPEEEREIIYRMGV----TPPQPKQILGTGDLLRLQD
MUL_1488|M.ulcerans_Agy99           RDRFLFKINVGYPTPEEEREIIYRMGV----TPPQPKQILGTGDLLRLQD
Mb1515|M.bovis_AF2122/97            RDRFLFKINVGYPSPEEEREIIYRMGV----TPPQAKQILSTGDLLRLQE
Rv1479|M.tuberculosis_H37Rv         RDRFLFKINVGYPSPEEEREIIYRMGV----TPPQAKQILSTGDLLRLQE
MLBr_01810|M.leprae_Br4923          RDRFLFKINVGYPSPEEEREIIYRMGV----TPPVPKQILNAGDLLRLQE
MAV_3299|M.avium_104                RDRFLFKINVGYPSPEEEREIIYRMGV----RPPEPKQILNTGDLVRLQD
Mflv_0039|M.gilvum_PYR-GCK          TDRFLLKEIVRYPSPEQEVDMMSRRDAGLYDKDHRSSPVVGLDDVRRLQR
Mvan_0879|M.vanbaalenii_PYR-1       TDRFLLKEIVRYPSPEQEVEVLARLDAGLFDKAHPVRPVATLDDIRRLQR
MSMEG_6612|M.smegmatis_MC2_155      TDRFMLKEIVRYPSVADEVEMIARMDAGLYERGRHGTPVVGIDDVRRVQR
TH_0628|M.thermoresistible__bu      TDRFMLKDILDYPSPQQEAEVIFRMDAGVYNRNQPTPPVVGLEDMRRLQE
MAB_0653|M.abscessus_ATCC_1997      MDRFMFKEILTYPNPAEEAEVVFRIDAGVYTN-HQGAPVASIQDILYIQD
                                     ***::*  : **.  :* ::: * ..           :    *:  :* 

MMAR_2286|M.marinum_M               IAANNFVHHALVDYVVRVVMATRQPEQLGMNDVKTWIAFGASPRASLGII
MUL_1488|M.ulcerans_Agy99           IAANNFVHHALVDYVVRVVMATRQPEQLGMNDVKTWIAFGASPRASLGII
Mb1515|M.bovis_AF2122/97            IAANNFVHHALVDYVVRVVFATRKPEQLGMNDVKSWVAFGASPRASLGII
Rv1479|M.tuberculosis_H37Rv         IAANNFVHHALVDYVVRVVFATRKPEQLGMNDVKSWVAFGASPRASLGII
MLBr_01810|M.leprae_Br4923          ISANNFVHHALVDYVVRVVTATRHPEQLGMNDVKTWISFGASPRASLGII
MAV_3299|M.avium_104                IAANVFVHHALVDYVVRVVTATRHPEQLGMNDVKTWISFGASPRASLGII
Mflv_0039|M.gilvum_PYR-GCK          ITRDVYMSRDLMLYASRLVGVTREPGNHLPSQLARMVEYGASPRATIALC
Mvan_0879|M.vanbaalenii_PYR-1       VTRDVYMSRDLMLYASRLVGVTREPGNYLPGQVARLIEYGASPRATIALC
MSMEG_6612|M.smegmatis_MC2_155      IAESVHLDRALVEYAGRLVGVTREPDSFLPTNLARLVEYGASPRATIALC
TH_0628|M.thermoresistible__bu      LVGRIHLDPVLVHYVTQLVHVTRNPQQYLPQQLARLVQYGASPRATIAFC
MAB_0653|M.abscessus_ATCC_1997      VVRRIYVDPAIVHYVTQIVNVTRNPKQYLPPNLARLIEYGASPRATIAFC
                                    :    .:   :: *. ::* .**.* .    ::   : :******::.: 

MMAR_2286|M.marinum_M               AASRALALVRGRDYVIPQDIIEVVPDVLRHRLVLTYDALADEISPEIVIN
MUL_1488|M.ulcerans_Agy99           AASRALALVRGRDYVIPQDIIEVVPDVLRHRLVLTYDALADEISPEIVIN
Mb1515|M.bovis_AF2122/97            AAARSLALVRGRDYVIPQDVIEVIPDVLRHRLVLTYDALADEISPEIVIN
Rv1479|M.tuberculosis_H37Rv         AAARSLALVRGRDYVIPQDVIEVIPDVLRHRLVLTYDALADEISPEIVIN
MLBr_01810|M.leprae_Br4923          KASRSLALVRGRDYVIPQDVIEVIPDVLRHRLVLTYNALADEISPEIVIN
MAV_3299|M.avium_104                AGARSLALVRGRDYVIPQDVVDVIPDVLRHRLVLTYDALADEISPEIVIN
Mflv_0039|M.gilvum_PYR-GCK          TAARALAVLSGRDHVIPSDIADLAHRVLQHRLILGFEAASAGVTPNRVID
Mvan_0879|M.vanbaalenii_PYR-1       TAARALALLSGRNHVVPGDIADLAHRVLQHRLILGFEAASAGITPDVVVD
MSMEG_6612|M.smegmatis_MC2_155      RTARALALLRGRDHVVPDDIARLAHRVLRHRLILGFEAASARITPDVVID
TH_0628|M.thermoresistible__bu      RSARAVALLQGRNHVLPDDIQRVAHRVLRHRLILGFEAMRLNVTPEMVID
MAB_0653|M.abscessus_ATCC_1997      KAARALALLADRNHVLPDDIKALAHRILRHRLILGFEAVAENVTAEVLID
                                      :*::*:: .*::*:* *:  :   :*:***:* ::*    ::.: :::

MMAR_2286|M.marinum_M               RVLQTVALPQVNAVPQQGHSVPPVMQAAAAAGGR
MUL_1488|M.ulcerans_Agy99           RVLQTVALPQVNAVPQQGHSVPPVMQAAAAAGGR
Mb1515|M.bovis_AF2122/97            RVLQTVALPQVNAVPQQGHSVPPVMQAAAAASGR
Rv1479|M.tuberculosis_H37Rv         RVLQTVALPQVNAVPQQGHSVPPVMQAAAAASGR
MLBr_01810|M.leprae_Br4923          RVLQTVALPQVNSFPQQGHSVPSVTQAAAAASGR
MAV_3299|M.avium_104                RVLQTVALPQVNAVPQQGHSVPPVMQPAGAASGR
Mflv_0039|M.gilvum_PYR-GCK          AVLHAVRVP-------------------------
Mvan_0879|M.vanbaalenii_PYR-1       AVLRAVRVP-------------------------
MSMEG_6612|M.smegmatis_MC2_155      AVLAAVRVP-------------------------
TH_0628|M.thermoresistible__bu      AVLQSVRVP-------------------------
MAB_0653|M.abscessus_ATCC_1997      NIIQAVRTP-------------------------
                                     :: :*  *