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VTSPSNLPRTVGELRASGHRERGVKQEIRENLLTALADGPDNAAVWPGIVGFDDTVIPQLERALIAGHDF VLLGERGQGKTRLLRALTGLLDEWTPVIAGAELPEHPYRPITPESIRRAAQLKDDLPVAWKHRSERYTEK LATPDTSVADLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAERIQVSMLNVMEERDI QVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLKDRFGAEIRTHYPLELEAEMGVIAQEAHLSAQVPDY LLQVIARFARYLRESSSVDQRSGVSARFAIAAAETVAAAARHRGAVLGETDPVARVVDLGTVIDVLRGKL EFESGEEGREQAVLEHLLRRATADTASRALGGIDVGTLVSAVEGGSAVTTGERVSAKDVLAAVPGLPVVE TIARKLNAESEGERAAALELALEALYLAKRVDKVSGEGQTVYG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4711 | - | - | 100% (464) | magnesium chelatase |
| M. ulcerans Agy99 | MUL_4275 | moxR2 | 2e-05 | 26.97% (89) | methanol dehydrogenase transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0983 | - | 0.0 | 94.79% (461) | magnesium chelatase |
| M. gilvum PYR-GCK | Mflv_1877 | - | 0.0 | 84.23% (463) | putative magnesium chelatase |
| M. tuberculosis H37Rv | Rv0958 | - | 0.0 | 94.58% (461) | magnesium chelatase |
| M. leprae Br4923 | MLBr_01810 | moxR | 2e-05 | 23.53% (187) | MoxR homolog |
| M. abscessus ATCC 19977 | MAB_2726c | - | 4e-05 | 26.72% (232) | hypothetical protein MAB_2726c |
| M. marinum M | MMAR_4541 | - | 0.0 | 99.35% (463) | magnesium chelatase |
| M. avium 104 | MAV_0412 | - | 3e-06 | 25.95% (131) | ATPase family protein associated with various cellular |
| M. smegmatis MC2 155 | MSMEG_5512 | - | 0.0 | 86.64% (464) | magnesium chelatase |
| M. thermoresistible (build 8) | TH_1334 | - | 0.0 | 85.53% (463) | POSSIBLE MAGNESIUM CHELATASE |
| M. vanbaalenii PYR-1 | Mvan_4854 | - | 0.0 | 85.53% (463) | putative magnesium chelatase |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4711|M.ulcerans_Agy99 MVTSPSNLPRTVGELRAS----GHRERGVKQEIRENLLTALADGPDNAAV
MMAR_4541|M.marinum_M -MTSPSNLPRTVGELRAS----GHRERGVKQEIRENLLTALADGPDNAAV
Mb0983|M.bovis_AF2122/97 --MSPSNLPRTVGELRAA----GHRERGVKQEIRENLLTALADGDN---V
Rv0958|M.tuberculosis_H37Rv --MSPSNLPRTVGELRAA----GHRERGVKQEIRENLLTALADGDN---V
MSMEG_5512|M.smegmatis_MC2_155 MVSQPKDLPRTVGELRAS----GHRERGVKAEIRENLLAALAERR---DV
TH_1334|M.thermoresistible__bu -VTQPNDLPRTVGELRAS----GHRERGVKQEIRENLLAALAGGR---DV
Mflv_1877|M.gilvum_PYR-GCK -MTSPNDLPRTVGELRAS----GHRERTVKAEIRENLLAALASGAPVDEV
Mvan_4854|M.vanbaalenii_PYR-1 -MTSPNDLPRTVGELRAS----GHQERSIKAEIRENLLSALASGAGADAV
MLBr_01810|M.leprae_Br4923 -MTSAGGLPVGADGCSGPGGQSGPRAHEAPPGGADGLVAEVHTLERAIFE
MAB_2726c|M.abscessus_ATCC_199 -MSSPG-QPGGGAGYTG--GSAGSAPHAPQGATSPALAAEVQNLERAIFE
MAV_0412|M.avium_104 -MTQPT-QPVTAS----------PTAESAR-----------EALLALRAE
.. * .
MUL_4711|M.ulcerans_Agy99 WPGIVGFDDTVIPQLERALIAGHDFVLLGERGQGKTRLLRALTGLLDEWT
MMAR_4541|M.marinum_M WPGIVGFDDTVIPQLERALIAGHDFVLLGERGQGKTRLLRALTGLLDEWT
Mb0983|M.bovis_AF2122/97 WPGILGFDDTVIPQVERALIAGHDFVLLGERGQGKTRLLRALAGLLDEWT
Rv0958|M.tuberculosis_H37Rv WPGILGFDDTVIPQVERALIAGHDFVLLGERGQGKTRLLRALAGLLDEWT
MSMEG_5512|M.smegmatis_MC2_155 WPGILGFEDTVIPQLERALIAGHDVVLLGERGQGKTRLLRALTGLLDEWT
TH_1334|M.thermoresistible__bu WPGILGFEDTVIPQLERALIAGHDVVLLGERGQGKTRLLRALIGLLDEWT
Mflv_1877|M.gilvum_PYR-GCK WPGILGFEDTVLPQLERALIAGHDIVLLGERGQGKTRLLRGLTGMLDEWT
Mvan_4854|M.vanbaalenii_PYR-1 WPGILGFEDTVIPQLERALIAGHDVVLLGERGQGKTRLLRALTNLLDEWT
MLBr_01810|M.leprae_Br4923 VKRVIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLAVETFARVVG---
MAB_2726c|M.abscessus_ATCC_199 VKRIIVGQDRLVERILVGLLAKGHVLLEGVPGVAKTLAVETFAKVVG---
MAV_0412|M.avium_104 LAKAVVGQEGVVSGLVIALLCRGHVLLEGVPGVAKTLLVRALAAALQ---
: :: :: : .*:. ..:* * * .** :. : :
MUL_4711|M.ulcerans_Agy99 PVIAGAELPEHPYRPITPESIRRAAQLKDDLPVAWKHRSERYTEKLATPD
MMAR_4541|M.marinum_M PVIAGAELPEHPYRPITPESIRRAAQLKDDLPVAWKHRSERYTEKLATPD
Mb0983|M.bovis_AF2122/97 PVIAGAELGEHPYTPITPESIRRAAQLGDDLPVAWKHRSERYTEKLATPD
Rv0958|M.tuberculosis_H37Rv PVIAGAELGEHPYTPITPESIRRAAQLGDDLPVAWKHRSERYTEKLATPD
MSMEG_5512|M.smegmatis_MC2_155 PVIAGSELGEHPYSPITPESIRRAADSGDDLPVEWRHRSERYTEKLATPD
TH_1334|M.thermoresistible__bu PVIAGSELGEHPYSPITPESIRRAADSGDDLPITWRHRSERYTEKLATPD
Mflv_1877|M.gilvum_PYR-GCK PVIAGAELGEHPYSPITPESIRRAADFGDDLPIAWRHRSERYTEKLATPD
Mvan_4854|M.vanbaalenii_PYR-1 PVIAGAELGEHPYSPITPESIRRAADSGDDLPITWRHRSERYTEKLATPD
MLBr_01810|M.leprae_Br4923 --------GTFARIQFTPDLVPTDIIG----TRIYRQGKEEFDTELGP--
MAB_2726c|M.abscessus_ATCC_199 --------GTFSRIQFTPDLVPTDIIG----TRIYRQGREEFDTELGP--
MAV_0412|M.avium_104 --------LEFKRVQFTPDLMPGDVTG----SLVYDARTAAFVFRPGP--
. :**: : . : : . ..
MUL_4711|M.ulcerans_Agy99 TSVADLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
MMAR_4541|M.marinum_M TSVADLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
Mb0983|M.bovis_AF2122/97 TSVADLVGDVDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
Rv0958|M.tuberculosis_H37Rv TSVADLVGDVDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
MSMEG_5512|M.smegmatis_MC2_155 TSVADLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
TH_1334|M.thermoresistible__bu TSVADLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
Mflv_1877|M.gilvum_PYR-GCK TSVADLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
Mvan_4854|M.vanbaalenii_PYR-1 TSVADLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
MLBr_01810|M.leprae_Br4923 ----------------------------------VVVNFLLADEINRAPA
MAB_2726c|M.abscessus_ATCC_199 ----------------------------------VVANFLLADEINRAPA
MAV_0412|M.avium_104 ----------------------------------VFTNLLLADEINRTPP
. .:: .:*: .
MUL_4711|M.ulcerans_Agy99 RIQVSMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLK
MMAR_4541|M.marinum_M RIQVSMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLK
Mb0983|M.bovis_AF2122/97 RIQVSMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPIK
Rv0958|M.tuberculosis_H37Rv RIQVSMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPIK
MSMEG_5512|M.smegmatis_MC2_155 RIQVAMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLK
TH_1334|M.thermoresistible__bu RIQVAMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLK
Mflv_1877|M.gilvum_PYR-GCK RIQVAMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLK
Mvan_4854|M.vanbaalenii_PYR-1 RIQVAMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLK
MLBr_01810|M.leprae_Br4923 KVQSALLEVMQERHVSIGGKTFPLPNPFLVMATQNPIEHEGVYLLPEAQR
MAB_2726c|M.abscessus_ATCC_199 KVQSALLEVMAERKISIGGKDYHLPKPFLVMATQNPIENEGVYPLPEAQR
MAV_0412|M.avium_104 KTQAALLEAMEERQVSVEGEAQPLPEPFIVAATQNPVEYEGTYQLPEAQL
: * ::*:.* **.:.: * ** .:* *: ** : . : .
MUL_4711|M.ulcerans_Agy99 DRFGAEIRTHYPLELEAEMGVIAQEAHLSAQVPDYLLQVIARFARYLRES
MMAR_4541|M.marinum_M DRFGAEIRTHYPLELEAEMGVIAQEAHLSAQVPEYLLQVIARFARYLRES
Mb0983|M.bovis_AF2122/97 DRFGAEIRTHYPLELEAEMGVIVQEAHLSAQVPDYLMQVLARFARYLRES
Rv0958|M.tuberculosis_H37Rv DRFGAEIRTHYPLELEAEMGVIVQEAHLSAQVSDYLMQVLARFARYLRES
MSMEG_5512|M.smegmatis_MC2_155 DRFGAEIRTHYPLELEAEVGVIRQEAELAAEVPEYLLAVLARFARNLRES
TH_1334|M.thermoresistible__bu DRFGAEIRTHYPQQLEAEVGVITQEAHLAAEVPEYLLHILARFTRNLRES
Mflv_1877|M.gilvum_PYR-GCK DRFGAEIRTHYPLELDAEVGVIVQEAHMAAEVPDYLLQILARFARALRES
Mvan_4854|M.vanbaalenii_PYR-1 DRFGAEIRTHYPPELDAEVGVITQEAHLAAEVPDYLLQILARFARSLRES
MLBr_01810|M.leprae_Br4923 DRFLFKINVGYP-SPEEEREIIYR--MGVTP---PVPKQILNAGDLLRLQ
MAB_2726c|M.abscessus_ATCC_199 DRFLFKINVDYP-TVEEEREIIYR--MGVTP---PEPKQILSSEALLRLQ
MAV_0412|M.avium_104 DRFLLKLNVTLP-PREAEIAILHRHAHGFDPRDLSVVQPVAGPADLAAGR
*** ::.. * : * :: : :
MUL_4711|M.ulcerans_Agy99 SSVDQRSGVSARFAIAAAETVAAAARHRGAVLGETDPVARVVDLGTVIDV
MMAR_4541|M.marinum_M SSVDQRSGVSARFAIAAAETVAAAARHRGAVLGETDPVARVVDLSTVIDV
Mb0983|M.bovis_AF2122/97 RSIDQRSGVSARFAIAAAETVAAAARHRGAVLGETDPVARVVDLGTVIDV
Rv0958|M.tuberculosis_H37Rv RSIDQRSGVSARFAIAAAETVAAAARHRGAVLGETDPVARVVDLGTVIDV
MSMEG_5512|M.smegmatis_MC2_155 NSIDQRSGVSARFAIAAAETVAASARHRAAILGEDDPVARVVDLGTVIDV
TH_1334|M.thermoresistible__bu PSIDQRSGVSARFAIAAAETVAASARHRSAILGEDDPVARVVDLGTVIEV
Mflv_1877|M.gilvum_PYR-GCK SSVDQRSGVSARFAIAAAETVAASARHRAAVLNEQEPVARVVDLASILDV
Mvan_4854|M.vanbaalenii_PYR-1 SSIDQRSGVSARFAIAAAETVAASARHRAALLGEQDPVARVVDLQNVIDV
MLBr_01810|M.leprae_Br4923 EISANNFVHHALVDYVVRVVTATRHPEQLGMNDVKTWISFGASPRASLGI
MAB_2726c|M.abscessus_ATCC_199 DLAANNFVHHALVDYVVRVIAATRNPAQFGLGDVANWISYGASPRASLGI
MAV_0412|M.avium_104 DAVQQVRVADEVLGYIVDIVGATRSSPALQL---------GVSPRGATAL
: . . *: : .. :
MUL_4711|M.ulcerans_Agy99 LRGKLEFESGEEGREQAVLEHLLRRATADTASRALGGIDVGTLVSAVEGG
MMAR_4541|M.marinum_M LRGKLEFESGEEGREQAVLEHLLRRATADTASRALGGIDVGTLVSAVEGG
Mb0983|M.bovis_AF2122/97 LRGKLEFESGEEGREQAVLEHLLRRATADTASRVLGGIDVGSLVTAVEGG
Rv0958|M.tuberculosis_H37Rv LRGKLEFESGEEGREQAVLEHLLRRATADTASRVLGGIDVGSLVTAVEGG
MSMEG_5512|M.smegmatis_MC2_155 LRGKLEFETGEEGREQAVLEHLLRRATADTAQRLLGGIDVGPLVAAIEEG
TH_1334|M.thermoresistible__bu LRGKLEFESGEEGRELAILEHLLRRATADTAQRLLGGIDVGPLVAAVEEG
Mflv_1877|M.gilvum_PYR-GCK LRGKLEFESGEEGREQAILEHLLRRATAETAQRLLGGIDVGPIVTAVEGG
Mvan_4854|M.vanbaalenii_PYR-1 LRGKLEFESGEEGREQAVLEHLLRRATAETAQRLLGGIDVGPIVTAVENG
MLBr_01810|M.leprae_Br4923 IKASRSLALVR-GRDYVIPQDVIEVIPDVLRHRLVLTYNA-----LADEI
MAB_2726c|M.abscessus_ATCC_199 IASARALALVR-GRDYVIPQDVIEVIPDVLRHRLVMSYDA-----LADEV
MAV_0412|M.avium_104 LATARSWSWLS-GRNYVTPDDVKAMARPTLRHRVMLRPEA-----ELEGA
: **: . :.: * : :. :
MUL_4711|M.ulcerans_Agy99 SAVTTGERVSAKDVLAAVPGLPVVETIARKLNAESEGERAAALELALEAL
MMAR_4541|M.marinum_M SAVTTGERVSAKDVLAAVPGLPVVETIARKLDAESEGERAAALELALEAL
Mb0983|M.bovis_AF2122/97 SAVTTGERVSAKDVLAAVPGLPVVDRIARKLGAESEGERAAALELALEAL
Rv0958|M.tuberculosis_H37Rv SAVTTGERVSAKDVLAAVPGLPVVDRIARKLGAESEGERAAALELALEAL
MSMEG_5512|M.smegmatis_MC2_155 SPVTTGERVSAKDVVAALPDLPAIDAIAHRLNAVSVGQRAAAIELALEAL
TH_1334|M.thermoresistible__bu SPVTTGERVSAKDVLAALPDLPVIDTITTRLGAQSIGQRAAAVELALEAL
Mflv_1877|M.gilvum_PYR-GCK SPVTTGDRVSARDVLAALPEVSAVAEIQQRLGAQTDGQRAAAIELALEAL
Mvan_4854|M.vanbaalenii_PYR-1 SPVTTGERVSAREVLAAVPEVSAVAEIQQRLGATSEGQRAAAMELALEAL
MLBr_01810|M.leprae_Br4923 SPEIVINRVLQTVALPQVNSFPQQGHSVP-------SVTQAAAAASGR--
MAB_2726c|M.abscessus_ATCC_199 SADTAINRILQTVGLPQVNAVPQQGNSVPPAMVGTNNPVPAAHNAAPR--
MAV_0412|M.avium_104 TCDGVLDGILASVPVPR---------------------------------
: . : : :.
MUL_4711|M.ulcerans_Agy99 YLAKRVDKVSGEGQTVYG
MMAR_4541|M.marinum_M YLAKRVDKVSGEGQTVYG
Mb0983|M.bovis_AF2122/97 YLAKRVDKVCGEGQTVYG
Rv0958|M.tuberculosis_H37Rv YLAKRVDKVCGEGQTVYG
MSMEG_5512|M.smegmatis_MC2_155 YLAKRIDKVSGEGETVYG
TH_1334|M.thermoresistible__bu YLAKRIDKQTGEGETIYG
Mflv_1877|M.gilvum_PYR-GCK YLAKRIDKVSDQGETVYG
Mvan_4854|M.vanbaalenii_PYR-1 YLAKRIDKVSDEGETVYG
MLBr_01810|M.leprae_Br4923 ------------------
MAB_2726c|M.abscessus_ATCC_199 ------------------
MAV_0412|M.avium_104 ------------------